Search

Your search keyword '"Saleem, Sarah"' showing total 653 results
Start Over Author "Saleem, Sarah" Search Limiters Available in Library Collection
653 results on '"Saleem, Sarah"'

1. Effect of 5-Minute Movies Shown via a Mobile Phone App on Risk Factors and Mortality After Stroke in a Low- to Middle-Income Country: Randomized Controlled Trial for the Stroke Caregiver Dyad Education Intervention (Movies4Stroke)

Author

Kamal, Ayeesha, Khoja, Adeel, Usmani, Bushra, Magsi, Shahvaiz, Malani, Aresha, Peera, Zahra, Sattar, Saadia, Ahmed Akram, Masood, Shahnawaz, Sumaira, Zulfiqar, Maryam, Muqeet, Abdul, Zaidi, Fabiha, Sayani, Saleem, Artani, Azmina, Azam, Iqbal, and Saleem, Sarah

Subjects
Information technology, T58.5-58.64, Public aspects of medicine, RA1-1270
Abstract

BackgroundPakistan is the sixth most populous nation in the world and has an estimated 4 million stroke survivors. Most survivors are taken care of by community-based caregivers, and there are no inpatient rehabilitation facilities. ObjectiveThe objective of this study was to evaluate the effectiveness and safety of locally designed 5-min movies rolled out in order of relevance that are thematically delivered in a 3-month program to deliver poststroke education to stroke survivor and caregiver dyads returning to the community. MethodsThis study was a randomized controlled, outcome assessor–blinded, parallel group, single-center superiority trial in which participants (stroke survivor-caregiver dyads) with first-ever stroke (both ischemic and hemorrhagic) incidence were randomized within 48 hours of their stroke into either the video-based education intervention group or the control group. The video-based education intervention group had health education delivered through short videos that were shown to the participants and their caregivers at the time of admission, before discharge, and the first and third months of follow-up after discharge. The control group had standardized care including predischarge education and counseling according to defined protocols. All participants enrolled in the video education intervention and control groups were followed for 12 months after discharge for outcome assessment in the outpatient stroke clinics. The primary outcome measures were the proportion of participants achieving control of blood pressure, blood sugar, and blood cholesterol in the video intervention versus the control group. Several predefined secondary outcomes were included in this study, of which we report the mortality and functional disability in this paper. Analysis was by performed using the intention-to-treat principle. ResultsA total of 310 stroke survivors and their caregiver dyads (participant dyads) were recruited over a duration of 6 months. In total, 155 participant dyads were randomized into the intervention and control groups, each. The primary outcome of control of three major risk factors revealed that at 12 months, there was a greater percentage of participants with a systolic BP

Published
2020
Full Text
View/download PDF

3. Diagnostic accuracy of ASQ for screening of neurodevelopmental delays in low resource countries.

Author

Manasyan, Albert, Salas, Ariel, Nolen, Tracy, Chomba, Elwyn, Mazariegos, Manolo, Tshefu Kitoto, Antoinette, Saleem, Sarah, Naqvi, Farnaz, Hambidge, K, Goco, Norman, McClure, Elizabeth, Biasini, Fred, Goldenberg, Robert, Bose, Carl, Koso-Thomas, Marion, Krebs, Nancy, Carlo, Waldemar, and Wallander, Jan

Subjects
community child health, developmental neurology & neurodisability, paediatric neurology, Child, Infant, Humans, Child, Preschool, Communication, Guatemala, Health Personnel, Income, Neurodevelopmental Disorders
Abstract

OBJECTIVE: The Bayley Scales of Infant Development (BSID) is the most used diagnostic tool to identify neurodevelopmental disorders in children under age 3 but is challenging to use in low-resource countries. The Ages and Stages Questionnaire (ASQ) is an easy-to-use, low-cost clinical tool completed by parents/caregivers that screens children for developmental delay. The objective was to determine the performance of ASQ as a screening tool for neurodevelopmental impairment when compared with BSID second edition (BSID-II) for the diagnosis of moderate-to-severe neurodevelopmental impairment among infants at 12 and 18 months of age in low-resource countries. METHODS: Study participants were recruited as part of the First Bites Complementary Feeding trial from the Democratic Republic of Congo, Zambia, Guatemala and Pakistan between October 2008 and January 2011. Study participants underwent neurodevelopmental assessment by trained personnel using the ASQ and BSID-II at 12 and 18 months of age. RESULTS: Data on both ASQ and BSID-II assessments of 1034 infants were analysed. Four of five ASQ domains had specificities greater than 90% for severe neurodevelopmental delay at 18 months of age. Sensitivities ranged from 23% to 62%. The correlations between ASQ communications subscale and BSID-II Mental Development Index (MDI) (r=0.38) and between ASQ gross motor subscale and BSID-II Psychomotor Development Index (PDI) (r=0.33) were the strongest correlations found. CONCLUSION: At 18 months, ASQ had high specificity but moderate-to-low sensitivity for BSID-II MDI and/or PDI

Published
2023

4. Maternal and perinatal outcomes of women with vaginal birth after cesarean section compared to repeat cesarean birth in select South Asian and Latin American settings of the global network for women’s and children’s health research

Author

Figueroa, Lester, Harrison, Margo, Mazariegos, Manolo, Goudar, Shivaprasad, Kavi, Avinash, Derman, Richard, Patel, Archana, Das, Prabir, Hibberd, Patricia L., Saleem, Sarah, Naqvi, Farnaz, Goldenberg, Robert L., Haque, Rashidul, Billah, Sk Masum, Petri, Jr., William A., McClure, Elizabeth M., Tan, Sylvia, and Krebs, Nancy F.

Published
2023
Full Text
View/download PDF

5. Building a predictive model of low birth weight in low- and middle-income countries: a prospective cohort study

Author

Patterson, Jackie K., Thorsten, Vanessa R., Eggleston, Barry, Nolen, Tracy, Lokangaka, Adrien, Tshefu, Antoinette, Goudar, Shivaprasad S., Derman, Richard J., Chomba, Elwyn, Carlo, Waldemar A., Mazariegos, Manolo, Krebs, Nancy F., Saleem, Sarah, Goldenberg, Robert L., Patel, Archana, Hibberd, Patricia L., Esamai, Fabian, Liechty, Edward A., Haque, Rashidul, Petri, Bill, Koso-Thomas, Marion, McClure, Elizabeth M., Bose, Carl L., and Bauserman, Melissa

Published
2023
Full Text
View/download PDF

6. B-Vitamins and Choline in Human Milk Are Not Impacted by a Preconception Lipid-Based Nutrient Supplement, but Differ Among Three Low-to-Middle Income Settings—Findings From the Women First Trial

Author

Young, Bridget E, Westcott, Jamie, Kemp, Jennifer, Allen, Lindsay, Hampel, Daniela, Garcés, Ana L, Figueroa, Lester, Goudar, Shivaprasad S, Dhaded, Sangappa M, Somannavar, Manjunath, Saleem, Sarah, Ali, Sumera Aziz, Hambidge, K Michael, Krebs, Nancy F, Group, The Women First Working, Herekar, Veena, Vernekar, Sunil S, Yogeshkumar, S, Khan, Umber, Abrejo, Farina, Goldenberg, Robert K, Derman, Richard J, and McClure, Beth

Subjects
Nutrition, Clinical Trials and Supportive Activities, Clinical Research, Prevention, Pediatric, 3.3 Nutrition and chemoprevention, Prevention of disease and conditions, and promotion of well-being, Reproductive health and childbirth, Zero Hunger, lipid nutrient supplement, human milk, B vitamins, thiamin, vitamin B12, nutrition intervention, infant growth, Women First Working Group, Agricultural Biotechnology, Nutrition and Dietetics
Abstract

Introduction: Optimal human milk (HM) B-vitamin concentrations remain undefined, especially in areas where undernutrition is prevalent. The impact of supplementation pre-conception through pregnancy on HM B-vitamin composition remains unknown. Methods: Human milk (HM) was collected at 2-weeks postpartum from 200 women in Guatemala, India, and Pakistan (the Women First Trial). The women were randomized to start a lipid-based nutrient supplement before conception, at end of the first trimester, or not at all; intervention continued until delivery. HM concentrations of eight B-vitamins and choline were assessed via ultra-performance liquid chromatography-tandem mass spectrometry. Maternal diet was assessed in early pregnancy, and infant growth followed through 6 months post-delivery. Results: Despite supplement exposure averaging 15.7 (pre-conception arm) and 6.0 months (prenatal arm), HM B-vitamins did not differ between arms, but site differences were evident. Guatemala had higher HM concentrations of vitamin B3 than Pakistan and India. Pakistan had higher HM concentrations of thiamin and vitamin B6 than India and Guatemala. Cohort average HM vitamin B2 (162 ± 79 μg/L) and B6 (31.8 ± 24.6 μg/L) fell below values defined as deficient in 81.5 and 85.5% of samples, potentially reflecting sampling procedures and timing. Maternal dietary intakes of only vitamin B6 and choline were associated with the corresponding concentrations in HM (p < 0.005). No HM B-vitamin concentrations were associated with infant growth. Conclusion: Prenatal supplementation for at least 6 months had no impact on HM B-vitamin concentrations at 2-weeks postpartum. Results suggest that the adequacy of HM composition was generally maintained, with potential exceptions of vitamin B2 and B6.

Published
2021

7. Cost-effectiveness of low-dose aspirin for the prevention of preterm birth: a prospective study of the Global Network for Women's and Children's Health Research

Author

Patterson, Jackie K, Neuwahl, Simon, Goco, Norman, Moore, Janet, Goudar, Shivaprasad S, Derman, Richard J, Hoffman, Matthew, Metgud, Mrityunjay, Somannavar, Manjunath, Kavi, Avinash, Okitawutshu, Jean, Lokangaka, Adrien, Tshefu, Antoinette, Bose, Carl L, Mwapule, Abigail, Mwenechanya, Musaku, Chomba, Elwyn, Carlo, Waldemar A, Chicuy, Javier, Figueroa, Lester, Krebs, Nancy F, Jessani, Saleem, Saleem, Sarah, Goldenberg, Robert L, Kurhe, Kunal, Das, Prabir, Patel, Archana, Hibberd, Patricia L, Achieng, Emmah, Nyongesa, Paul, Esamai, Fabian, Bucher, Sherri, Liechty, Edward A, Bresnahan, Brian W, Koso-Thomas, Marion, and McClure, Elizabeth M

Published
2023
Full Text
View/download PDF

8. The causes of preterm neonatal deaths in India and Pakistan (PURPOSe): a prospective cohort study

Author

Goudar, Shivaprasad, Dhaded, Sangappa M, Nagmoti, Mahantesh B, Somannavar, Manjunath S, Yogeshkumar, S, Harakuni, Sheetal, Guruprasad, Gowdar, Aradhya, Gayathri H, Nadig, Naveen, Kusgur, Varun, Raghoji, Chaitali R, Sarvamangala, B, Prakash, Veena, Joish, Upendra Kumar, Mangala, G K, Rajashekhar, K S, Sunilkumar, K Byranahalli, Kulkarni, Vardendra, Siddartha, ES, Patil, Lingaraja Gowda C, Pujar, Sneharoopa, Dhananjaya, Shobha, Nagaraj, TS, Jeevika, MU, Harikiran, Reddy R, Saleem, Sarah, Tikmani, Shiyam Sunder, Zafar, Afia, Ahmed, Imran, Uddin, Zeeshan, Ghanchi, Najia, Roujani, Sana, Ariff, Shabina, Sheikh, Lumaan, Mirza, Waseem, Yasmin, Haleema, Raza, Jamal, Prakash, Jai, Haider, Furqan, Aceituno, Anna, Parlberg, Lindsay, Moore, Janet L, Hwang, Kay, Parepelli, Suchita, Kim, Jean, Bann, Carla, McClure, Elizabeth, Goldenberg, Robert, Silver, Robert, Goudar, Shivaprasad S, Kusagur, Varun B, Reza, Sayyeda, Moore, Janet, Bann, Carla M, Silver, Robert M, Goldenberg, Robert L, and McClure, Elizabeth M

Published
2022
Full Text
View/download PDF

9. The causes of stillbirths in south Asia: results from a prospective study in India and Pakistan (PURPOSe)

Author

Goudar, Shivaprasad, Dhaded, Sangappa M, Nagmoti, Mahantesh B, Somannavar, Manjunath S, Yogeshkumar, S, Guruprasad, Gowdar, Aradhya, Gayathri H, Nadig, Naveen, Kusgur, Varun, Raghoji, Chaitali R, Sarvamangala, B, Prakash, Veena, Joish, Upendra Kumar, Mangala, G K, Rajashekhar, K S, Kumar, Sunil, Kulkarni, Vardendra, Saleem, Sarah, Tikmani, Shiyam Sunder, Zafar, Afia, Ahmed, Imran, Uddin, Zeeshan, Ghanchi, Najia, Ariff, Shabina, Sheikh, Lumaan, Mirza, Waseem, Yasmin, Haleema, Raza, Jamal, Prakash, Jai, Haider, Furqan, Aceituno, Anna, Parlberg, Lindsay, Moore, Janet L, Hwang, Kay, Parepelli, Suchita, Kim, Jean, Bann, Carla, McClure, Elizabeth, Goldenberg, Robert, McClure, Elizabeth M, Goudar, Shivaprasad S, Shobha, Dhananjaya, Roujani, Sana, Reza, Sayyeda, Bann, Carla M, Silver, Robert M, and Goldenberg, Robert L

Published
2022
Full Text
View/download PDF

14. The efficacy of low-dose aspirin in pregnancy among women in malaria-endemic countries

Author

Bauserman, Melissa, Leuba, Sequoia I., Hemingway-Foday, Jennifer, Nolen, Tracy L., Moore, Janet, McClure, Elizabeth M., Lokangaka, Adrien, Tsehfu, Antoinette, Patterson, Jackie, Liechty, Edward A., Esamai, Fabian, Carlo, Waldemar A., Chomba, Elwyn, Goldenberg, Robert L., Saleem, Sarah, Jessani, Saleem, Koso-Thomas, Marion, Hoffman, Matthew, Derman, Richard J., Meshnick, Steven R., and Bose, Carl L.

Published
2022
Full Text
View/download PDF

16. Exploring gestational age, and birth weight assessment in Thatta district, Sindh, Pakistan: Healthcare providers’ knowledge, practices, perceived barriers, and the potential of a mobile app for identifying preterm and low birth weight

Author

Tikmani, Shiyam Sunder, primary, Mårtensson, Thomas, additional, Roujani, Sana, additional, Feroz, Anam Shahil, additional, Seyfulayeva, Ayshe, additional, Mårtensson, Andreas, additional, Brown, Nick, additional, and Saleem, Sarah, additional

Published
2024
Full Text
View/download PDF

17. Impact of Drain Placement on Postoperative Complications after Thyroidectomy for Substernal Goiter

Author

Waqar, Usama, additional, Hameed, Ayesha Nasir, additional, Angez, Meher, additional, Kumar, Sudhesh, additional, Arshad, Hajra, additional, Siddiqui, Marium Tariq, additional, Khan, Hira, additional, Viquar, Werdah, additional, Abbas, Aiza, additional, Javid, Arsalan, additional, Iftikhar, Haissan, additional, Abbas, Syed Akbar, additional, Naz, Huma, additional, and Saleem, Sarah, additional

Published
2024
Full Text
View/download PDF

18. Assessing the diagnostic accuracy of postnatal clinical scoring methods and foot length measurement for estimating gestational age and birthweight of newborns in low- and middle-income countries : a systematic review and meta-analysis

Author

Tikmani Sunder, Shiyam, Mårtensson, Thomas, Khalid, Sumaira, Uzair, Muhammad, Ali, Qammerulanissa, Rahim, Anum, Mårtensson, Andreas, Saleem, Sarah, Brown, Nick, Tikmani Sunder, Shiyam, Mårtensson, Thomas, Khalid, Sumaira, Uzair, Muhammad, Ali, Qammerulanissa, Rahim, Anum, Mårtensson, Andreas, Saleem, Sarah, and Brown, Nick

Abstract

Background This study aimed to update systematic reviews and meta-analyses on the diagnostic accuracy of postnatal clinical scoring (PCS) methods and foot length (FL) measurement for assessing gestational age (GA) and birth weight in low-income and middle-income countries (LMICs). In addition, the quality of reference standards, including antenatal ultrasound (A-US), last menstrual period (LMP), PCS and newborn weighing scales, was also evaluated. Methods Studies from LMICs published between January 2000 and February 2024 were searched, using databases such as PubMed, Web of Science, Cochrane Library, CINAHL and Scopus. Studies that compared PCS and/or FL with LMP and/or A-US to estimate GA or used calibrated newborn weighing scales for birthweight estimation were included. The risk of bias was assessed using the Quality Assessment of Diagnostic Accuracy Studies-II tool and evaluated the quality of the reference standards. When sufficient data were available, pooled estimates were calculated using random-effects models. Results A total of 50 studies were included. A-US was a reasonable tool for GA assessment if conducted by physicians using fetal biometry and the Hadlock method for GA estimation. LMP was reasonable when women had regular cycles, knew their LMP, were not using contraceptives and LMP data were collected by healthcare providers. When A-US was used as the reference standard, PCS methods estimated GA with a precision of +/- 2.8 to +/- 3.2 weeks. FL measurement <7.5 cm showed a pooled sensitivity of 76.2% and specificity of 36.6% for identifying preterm birth. FL measurement <= 7.6 cm had a pooled sensitivity of 78.6% and specificity of 65.7% for identifying low birth weight (LBW). High heterogeneity across studies was observed. Conclusion This systematic review and meta-analysis highlights significant variability and methodological inconsistencies in using PCS methods and FL measurement for estimating GA and LBW in LMICs. The observed high heteroge

Published
2024
Full Text
View/download PDF

19. Diagnostic accuracy of foot length measurement for identification of preterm newborn in rural Sindh, Pakistan

Author

Sundar Tikmani, Shiyam, Brown, Nick, Inayat, Alijaan, Mårtensson, Andreas, Saleem, Sarah, Mårtensson, Thomas, Sundar Tikmani, Shiyam, Brown, Nick, Inayat, Alijaan, Mårtensson, Andreas, Saleem, Sarah, and Mårtensson, Thomas

Abstract

Introduction Assessing gestational age accurately is crucial for saving preterm newborns. In low and middle-income countries, such as Pakistan, where access to antenatal ultrasonography (A-USG) is limited, alternative methods are needed. This study evaluated the diagnostic accuracy of foot length (FL) measurement for identifying preterm newborns in rural Pakistan using A-USG as the reference standard. Methods A test validation study was conducted between January and June 2023 in rural Sindh, Pakistan, within the catchment area of the Global Network for Maternal Newborn Health Registry, Thatta. Singleton newborns whose mothers had an A-USG before 20 weeks of gestation were enrolled. A research assistant measured FL three times using a rigid transparent plastic ruler within 48 hours of birth and the average FL was reported. Sensitivity, specificity, positive and negative predictive values (PPV, NPV) and likelihood ratios were calculated. The optimal FL cut-off for the identification of preterm newborns was determined using the Youden Index. Results A total of 336 newborns were included in the final analysis, of whom 75 (22.3%) were born before 37 weeks of gestation. The median gestational age of the newborns was 38.2 weeks, and the median FL was 7.9 cm. The area under the curve was 97.6%. The optimal FL cut-off for identifying preterm newborns was considered as ≤7.6 cm with a sensitivity of 90.8%, specificity of 96.0%, PPV of 86.7% and NPV of 97.3%. A lower cut-off of ≤7.5 cm had a sensitivity of 95.4%, specificity of 84.0%, PPV of 63.1% and NPV of 98.5%. Conclusion In conclusion, this study highlights the utility of FL measurement for identifying preterm newborns in rural settings where A-USG is unavailable before 20 weeks of gestation. Optimal cut-offs of ≤7.6 and ≤7.5 cm provide a simple, cost-effective and reliable tool for clinicians and frontline healthcare providers in rural areas, respectively.

Published
2024
Full Text
View/download PDF

20. Exploring gestational age, and birth weight assessment in Thatta district, Sindh, Pakistan : Healthcare providers' knowledge, practices, perceived barriers, and the potential of a mobile app for identifying preterm and low birth weight

Author

Sunder Tikmani, Shiyam, Mårtensson, Thomas, Roujani, Sana, Feroz, Anam Shahil, Seyfulayeva, Ayshe, Mårtensson, Andreas, Brown, Nick, Saleem, Sarah, Sunder Tikmani, Shiyam, Mårtensson, Thomas, Roujani, Sana, Feroz, Anam Shahil, Seyfulayeva, Ayshe, Mårtensson, Andreas, Brown, Nick, and Saleem, Sarah

Abstract

Introduction Reliable methods for identifying prematurity and low birth weight (LBW) are crucial to ending preventable deaths in newborns. This study explored healthcare providers’ (HCPs) knowledge, practice, perceived barriers in assessing gestational age and birth weight and their referral methods for preterm and LBW infants. The study additionally assessed the potential of using a mobile app for the identification and referral decision of preterm and LBW. Methods This qualitative descriptive study was conducted in Thatta District, Sindh, Pakistan. Participants, including doctors, nurses, lady health visitors, and midwives, were purposefully selected from a district headquarter hospital, and private providers in the catchment area of Global Network’s Maternal and Newborn Health Registry (MNHR). Interviews were conducted using an interview guide after obtaining written informed consent. Audio recordings of the interviews were transcribed and analyzed using NVIVO® software with an inductive approach. Results The HCPs had extensive knowledge about antenatal and postnatal methods for assessing gestational age. They expressed a preference for antenatal ultrasound due to the perceived accuracy, though accept practical barriers including workload, machine malfunctions, and cost. Postnatal assessment using the Ballard score was only undertaken sparingly due to insufficient training and subjectivity. All HCPs preferred electronic weighing scales for birth weight Barriers encountered included weighing scale calibration and battery issues. There was variation in the definition of prematurity and LBW, leading to delays in referral. Limited resources, inadequate education, and negative parent past experiences were barriers to referral. Foot length measurements were not currently being used. While mobile apps are felt to have potential, unreliable electricity supply and internet connectivity are barriers. Conclusion The HCPs in this study were knowledgeable in terms of potentia, De två första författarna delar förstaförfattarskapetDe två sista författarna delar sistaförfattarskapet

Published
2024
Full Text
View/download PDF

21. Longitudinal Changes of One-Carbon Metabolites and Amino Acid Concentrations during Pregnancy in the Women First Maternal Nutrition Trial

Author

Gilley, Stephanie P, Weaver, Nicholas E, Sticca, Evan L, Jambal, Purevsuren, Palacios, Alexandra, Kerns, Mattie E, Anand, Pratibha, Kemp, Jennifer F, Westcott, Jamie E, Figueroa, Lester, Garcés, Ana Lucía, Ali, Sumera A, Pasha, Omrana, Saleem, Sarah, Hambidge, K Michael, Hendricks, Audrey E, Krebs, Nancy F, and Borengasser, Sarah J

Published
2020
Full Text
View/download PDF

23. Predictors of Preterm Neonatal Mortality in India and Pakistan: A Secondary Analysis of Data from PURPOSe Study

Author

Tikmani, Shiyam Sunder, primary, Saleem, Sarah, additional, Sadia, Afreen, additional, M. Bann, Carla, additional, Bozdar, Muhammad Hayat, additional, Raza, Jamal, additional, Dhaded, Sangappa M., additional, Goudar, Shivaprasad S., additional, Gowdar, Guruparasad, additional, Yasmin, Haleema, additional, McClure, Elizabeth M., additional, and Goldenberg, Robert L., additional

Published
2024
Full Text
View/download PDF

27. Role of fingolimod in acute respiratory distress syndrome.

Author

Jahan, Sarwat, Khan, Manzoor, Zahir, Salman, Khan, Khansa, and Saleem, Sarah

Subjects
ADULT respiratory distress syndrome, SPHINGOSINE-1-phosphate, RESPIRATORY distress syndrome, LITERATURE reviews, CLINICAL medicine
Abstract

Objective: Sphingosine 1 Phosphate (S1P) is a key regulator of inflammation, angiogenesis, vessel permeability, and immune processes, acting through S1P receptors. Fingolimod (FTY720), an S1P receptor analog Fingolimod, was initially approved for multiple sclerosis treatment and has shown potential for application in infectious and inflammatory disorders, including COVID-19. Study Design: Comprehensive Literature Review. Setting: Northwest School of Medicine. Period: 1st March 2023 to 3rd July 2023. Methods: Examining S1P pathways, S1P receptor analogs, and their potential in treating inflammatory and infectious disorders, particularly COVID-19, utilizing Fingolimod. Results: S1P analogs have demonstrated therapeutic benefits in autoimmune diseases. In COVID-19, these analogs modulate the inflammatory response, reduce tissue damage, and promote viral clearance. Fingolimod, in particular, affects S1PR1, S1PR4, and S1PR5, blunting the inflammatory response and mitigating lung tissue injury. Early administration may prevent excessive inflammation without interfering with viral clearance. Potential risks include disturbance of cytokine homeostasis and delayed administration. Limited human studies and concerns about off-target effects need addressing. Conclusion: Fingolimod shows promise in treating COVID-19 by reducing inflammation and lung damage. Further research is needed to address limitations and ensure safety for clinical application. Sphingosine 1 Phosphate (S1P) plays a key role in regulating inflammation and immune responses, with Fingolimod being a potential treatment option. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

28. Maternal age extremes and adverse pregnancy outcomes in low-resourced settings

Author

Nyongesa, Paul, primary, Ekhaguere, Osayame A., additional, Marete, Irene, additional, Tenge, Constance, additional, Kemoi, Milsort, additional, Bann, Carla M., additional, Bucher, Sherri L., additional, Patel, Archana B., additional, Hibberd, Patricia L., additional, Naqvi, Farnaz, additional, Saleem, Sarah, additional, Goldenberg, Robert L., additional, Goudar, Shivaprasad S., additional, Derman, Richard J., additional, Krebs, Nancy F., additional, Garces, Ana, additional, Chomba, Elwyn, additional, Carlo, Waldemar A., additional, Mwenechanya, Musaku, additional, Lokangaka, Adrien, additional, Tshefu, Antoinette K., additional, Bauserman, Melissa, additional, Koso-Thomas, Marion, additional, Moore, Janet L., additional, McClure, Elizabeth M., additional, Liechty, Edward A., additional, and Esamai, Fabian, additional

Published
2023
Full Text
View/download PDF

33. Can the date of last menstrual period be trusted in the first trimester? Comparisons of gestational age measures from a prospective cohort study in six low-income to middle-income countries

Author

Patel, Archana, primary, Bann, Carla M, additional, Thorsten, Vanessa R, additional, Rao, Sowmya R, additional, Lokangaka, Adrien, additional, Tshefu Kitoto, Antoinette, additional, Bauserman, Melissa, additional, Figueroa, Lester, additional, Krebs, Nancy F, additional, Esamai, Fabian, additional, Bucher, Sherri, additional, Saleem, Sarah, additional, Goldenberg, Robert L, additional, Chomba, Elwyn, additional, Carlo, Waldemar A, additional, Goudar, Shivaprasad, additional, Derman, Richard, additional, Koso-Thomas, Marion, additional, McClure, Elizabeth, additional, and Hibberd, Patricia L, additional

Published
2023
Full Text
View/download PDF

34. An approach to identify a minimum and rational proportion of caesarean sections in resource-poor settings: a global network study

Author

Belizán, José M, Minckas, Nicole, McClure, Elizabeth M, Saleem, Sarah, Moore, Janet L, Goudar, Shivaprasad S, Esamai, Fabian, Patel, Archana, Chomba, Elwyn, Garces, Ana L, Althabe, Fernando, Harrison, Margo S, Krebs, Nancy F, Derman, Richard J, Carlo, Waldemar A, Liechty, Edward A, Hibberd, Patricia L, Buekens, Pierre M, and Goldenberg, Robert L

Published
2018
Full Text
View/download PDF

36. Institutional deliveries and stillbirth and neonatal mortality in the Global Network's Maternal and Newborn Health Registry

Author

Goudar, Shivaprasad S., Goco, Norman, Somannavar, Manjunath S., Kavi, Avinash, Vernekar, Sunil S., Tshefu, Antoinette, Chomba, Elwyn, Garces, Ana L., Saleem, Sarah, Naqvi, Farnaz, Patel, Archana, Esamai, Fabian, Bose, Carl L., Carlo, Waldemar A., Krebs, Nancy F., Hibberd, Patricia L., Liechty, Edward A., Koso-Thomas, Marion, Nolen, Tracy L., Moore, Janet, Iyer, Pooja, McClure, Elizabeth M., Goldenberg, Robert L., and Derman, Richard J.

Published
2020
Full Text
View/download PDF

37. Cesarean birth in the Global Network for Women’s and Children’s Health Research: trends in utilization, risk factors, and subgroups with high cesarean birth rates

Author

Harrison, Margo S., Garces, Ana L., Goudar, Shivaprasad S., Saleem, Sarah, Moore, Janet L., Esamai, Fabian, Patel, Archana B., Chomba, Elwyn, Bose, Carl L., Liechty, Edward A., Krebs, Nancy F., Derman, Richard J., Hibberd, Patricia L., Carlo, Waldemar A., Tshefu, Antoinette, Koso-Thomas, Marion, McClure, Elizabeth M., and Goldenberg, Robert L.

Published
2020
Full Text
View/download PDF

38. Association of parity with birthweight and neonatal death in five sites: The Global Network’s Maternal Newborn Health Registry study

Author

Garces, Ana, Perez, Wilton, Harrison, Margo S., Hwang, Kay S., Nolen, Tracy L., Goldenberg, Robert L., Patel, Archana B., Hibberd, Patricia L., Lokangaka, Adrien, Tshefu, Antoinette, Saleem, Sarah, Goudar, Shivaprasad S., Derman, Richard J., Patterson, Jacquelyn, Koso-Thomas, Marion, McClure, Elizabeth M., Krebs, Nancy F., and Hambidge, K. Michael

Published
2020
Full Text
View/download PDF

39. Why are the Pakistani maternal, fetal and newborn outcomes so poor compared to other low and middle-income countries?

Author

Aziz, Aleha, Saleem, Sarah, Nolen, Tracy L., Pradhan, Nousheen Akber, McClure, Elizabeth M., Jessani, Saleem, Garces, Ana L., Hibberd, Patricia L., Moore, Janet L., Goudar, Shivaprasad S., Dhaded, Sangappa M., Esamai, Fabian, Tenge, Constance, Patel, Archana B., Chomba, Elwyn, Mwenechanya, Musaku, Bose, Carl L., Liechty, Edward A., Krebs, Nancy F., Derman, Richard J., Carlo, Waldemar A., Tshefu, Antoinette, Koso-Thomas, Marion, Siddiqi, Sameen, and Goldenberg, Robert L.

Published
2020
Full Text
View/download PDF

40. Maternal mortality in six low and lower-middle income countries from 2010 to 2018: risk factors and trends

Author

Bauserman, Melissa, Thorsten, Vanessa R., Nolen, Tracy L., Patterson, Jackie, Lokangaka, Adrien, Tshefu, Antoinette, Patel, Archana B., Hibberd, Patricia L., Garces, Ana L., Figueroa, Lester, Krebs, Nancy F., Esamai, Fabian, Nyongesa, Paul, Liechty, Edward A., Carlo, Waldemar A., Chomba, Elwyn, Goudar, Shivaprasad S., Kavi, Avinash, Derman, Richard J., Saleem, Sarah, Jessani, Saleem, Billah, Sk Masum, Koso-Thomas, Marion, McClure, Elizabeth M., Goldenberg, Robert L., and Bose, Carl

Published
2020
Full Text
View/download PDF

41. Regional trends in birth weight in low- and middle-income countries 2013–2018

Author

Marete, Irene, Ekhaguere, Osayame, Bann, Carla M., Bucher, Sherri L., Nyongesa, Paul, Patel, Archana B., Hibberd, Patricia L., Saleem, Sarah, Goldenberg, Robert L., Goudar, Shivaprasad S., Derman, Richard J., Garces, Ana L., Krebs, Nancy F., Chomba, Elwyn, Carlo, Waldemar A., Lokangaka, Adrien, Bauserman, Melissa, Koso-Thomas, Marion, Moore, Janet L., McClure, Elizabeth M., and Esamai, Fabian

Published
2020
Full Text
View/download PDF

42. Development of the Global Network for Women’s and Children’s Health Research’s socioeconomic status index for use in the network’s sites in low and lower middle-income countries

Author

Patel, Archana B., Bann, Carla M., Garces, Ana L., Krebs, Nancy F., Lokangaka, Adrien, Tshefu, Antoinette, Bose, Carl L., Saleem, Sarah, Goldenberg, Robert L., Goudar, Shivaprasad S., Derman, Richard J., Chomba, Elwyn, Carlo, Waldemar A., Esamai, Fabian, Liechty, Edward A., Koso-Thomas, Marion, McClure, Elizabeth M., and Hibberd, Patricia L.

Published
2020
Full Text
View/download PDF

43. Rates and risk factors for preterm birth and low birthweight in the global network sites in six low- and low middle-income countries

Author

Pusdekar, Yamini V., Patel, Archana B., Kurhe, Kunal G., Bhargav, Savita R., Thorsten, Vanessa, Garces, Ana, Goldenberg, Robert L., Goudar, Shivaprasad S., Saleem, Sarah, Esamai, Fabian, Chomba, Elwyn, Bauserman, Melissa, Bose, Carl L., Liechty, Edward A., Krebs, Nancy F., Derman, Richard J., Carlo, Waldemar A., Koso-Thomas, Marion, Nolen, Tracy L., McClure, Elizabeth M., and Hibberd, Patricia L.

Published
2020
Full Text
View/download PDF

45. Prevention of maternal and neonatal death/infections with a single oral dose of azithromycin in women in labour in low-income and middle-income countries (A-PLUS): a study protocol for a multinational, randomised placebo-controlled clinical trial

Author

Hemingway-Foday, Jennifer, primary, Tita, Alan, additional, Chomba, Elwyn, additional, Mwenechanya, Musaku, additional, Mweemba, Trecious, additional, Nolen, Tracy, additional, Lokangaka, Adrien, additional, Tshefu Kitoto, Antoinette, additional, Lomendje, Gustave, additional, Hibberd, Patricia L, additional, Patel, Archana, additional, Das, Prabir Kumar, additional, Kurhe, Kunal, additional, Goudar, Shivaprasad S, additional, Kavi, Avinash, additional, Metgud, Mrityunjay, additional, Saleem, Sarah, additional, Tikmani, Shiyam S, additional, Esamai, Fabian, additional, Nyongesa, Paul, additional, Sagwe, Amos, additional, Figueroa, Lester, additional, Mazariegos, Manolo, additional, Billah, Sk Masum, additional, Haque, Rashidul, additional, Shahjahan Siraj, Md, additional, Goldenberg, Robert L, additional, Bauserman, Melissa, additional, Bose, Carl, additional, Liechty, Edward A, additional, Ekhaguere, Osayame A, additional, Krebs, Nancy F, additional, Derman, Richard, additional, Petri, William A, additional, Koso-Thomas, Marion, additional, McClure, Elizabeth, additional, and Carlo, Waldemar A, additional

Published
2023
Full Text
View/download PDF

46. P17-058-23 Seasonal and Ambient Temperature-Associated Changes in Human Milk Constituents Among Women in Rural Pakistan

Author

Shankar, Kartik, primary, Ali, Sumera, additional, Young, Bridget, additional, Jessani, Saleem, additional, Gilley, Stephanie, additional, Kemp, Jennifer, additional, Westcott, Jamie, additional, Bode, Lars, additional, Saleem, Sarah, additional, Goldenberg, Robert, additional, Hambidge, Michael, additional, and Krebs, Nancy, additional

Published
2023
Full Text
View/download PDF

47. Early recognition and management of maternal sepsis in Pakistan: a feasibility study of the implementation of FAST-M intervention

Author

Ahmed, Sheikh Irfan, primary, Rind, Ghulam Kubra, additional, Sikandar, Raheel, additional, Raza, Amir, additional, Khowaja, Bakhtawar M Hanif, additional, Parveen, Fahmida, additional, Khan, Sehrish, additional, Memon, Nazia, additional, Jahangir, Arshia, additional, Mirza, Daayl Naim, additional, Cheshire, James, additional, Dunlop, Catherine Louise, additional, Shakoor, Sadia, additional, Barolia, Rubina, additional, Sheikh, Lumaan, additional, Saleem, Sarah, additional, Coomarasamy, Arri, additional, and Lissauer, David, additional

Published
2023
Full Text
View/download PDF

49. Evaluating the effect of care around labor and delivery practices on early neonatal mortality in the Global Network’s Maternal and Newborn Health Registry

Author

Patel, Archana B., Simmons, Elizabeth M., Rao, Sowmya R., Moore, Janet, Nolen, Tracy L., Goldenberg, Robert L., Goudar, Shivaprasad S., Somannavar, Manjunath S., Esamai, Fabian, Nyongesa, Paul, Garces, Ana L., Chomba, Elwyn, Mwenechanya, Musaku, Saleem, Sarah, Naqvi, Farnaz, Bauserman, Melissa, Bucher, Sherri, Krebs, Nancy F., Derman, Richard J., Carlo, Waldemar A., Koso-ThomasMcClure, Marion Elizabeth M., and Hibberd, Patricia L.

Published
2020
Full Text
View/download PDF

50. The relationship between birth intervals and adverse maternal and neonatal outcomes in six low and lower-middle income countries

Author

Bauserman, Melissa, Nowak, Kayla, Nolen, Tracy L., Patterson, Jackie, Lokangaka, Adrien, Tshefu, Antoinette, Patel, Archana B., Hibberd, Patricia L., Garces, Ana L., Figueroa, Lester, Krebs, Nancy F., Esamai, Fabian, Liechty, Edward A., Carlo, Waldemar A., Chomba, Elwyn, Mwenechanya, Musaku, Goudar, Shivaprasad S., Ramadurg, Umesh, Derman, Richard J., Saleem, Sarah, Jessani, Saleem, Koso-Thomas, Marion, McClure, Elizabeth M., Goldenberg, Robert L., and Bose, Carl

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results