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2. Radioprotection by pressor amidines.

Author

ROTHE WE, GRENAN MM, and WILSON SM

Subjects
Animals, Mice, Amidines, Amines, Guanidines, Pyridines, Radiation Protection, Radiation-Protective Agents
Abstract

In the mouse, radioprotection is not always associated with the effect of hypertensive amidines and related amines. The protection resulting from this group of agents follows the pharmacological reduction of intercellular oxygen tension. oxygen tension of radiosensitive tissues.

Published
1963
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3. Radioprotection by mitotic inhibitors and mercaptoethylamine.

Author

ROTHE WE and GRENAN MM

Subjects
Animals, Mice, X-Rays, Bone Marrow, Cell Division pharmacology, Cysteamine, Mercaptoethylamines pharmacology, Radiation Protection
Abstract

In the mouse, chemical interference with cellular proliferation alters the radiosensitivity of the bone marrow, and this results in protection from otherwise lethal x-irradiation. When intestinal damage is minimized by appropriate timing and dosage, many mitotic inhibitors increase radioresistance and enhance the protective effects of mercaptoethylamine.

Published
1961
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