8 results on '"Principato S"'
Search Results
2. Holocene Sediment Magnetic Properties along a Transect From Ísafjardardjúp to Djúpáll, Northwest Iceland
- Author
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Andrews, J. T., primary, Hardardóttir, J., additional, Stoner, J. S., additional, and Principato, S. M., additional
- Published
- 2008
- Full Text
- View/download PDF
3. Body mass index and bioelectrical vector distribution in 8-year-old children
- Author
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Nunzia Ruggiero Perrino, Silvestre Principato, Pierluigi Pecoraro, Roberta Laccetti, Bruna Guida, Claudio Falconi, Angelo Pietrobelli, Rossella Trio, Guida, Bruna, Pietrobelli, A, Trio, Rossella, Laccetti, Roberta, Falconi, Claudio, Perrino, Nr, Principato, S, and Pecoraro, P.
- Subjects
Male ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,Body water ,Population ,Medicine (miscellaneous) ,Overweight ,Body Mass Index ,Body Water ,Reference Values ,BIA ,Internal medicine ,medicine ,Electric Impedance ,Body Fat Distribution ,Humans ,Body Weights and Measures ,Obesity ,body water ,lean mass tissue ,fat mass ,education ,Child ,Children ,education.field_of_study ,Nutrition and Dietetics ,business.industry ,Weight change ,Phase angle ,Reproducibility of Results ,Water-Electrolyte Balance ,medicine.disease ,Surgery ,Fat-free mass ,Skinfold Thickness ,Italy ,Bioelectrical impedance vector analysi ,Cardiology ,Body Composition ,Female ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Body mass index ,Bioelectrical impedance analysis - Abstract
OBJECTIVE: To describe bioelectrical impedance vector distribution in relation to BMI (body mass index; body weight/stature(2)) in a population of healthy children in order to detect possible changes in body composition status. DESIGN: Observational study involving 464 healthy 8-year-old children. The subjects were divided into three groups based on their BMI: 218 normal weight (NW) children with BMI/=21.6. Skinfold thickness was measured at the triceps using a Holtain caliper. Bioelectrical impedance analysis (BIA) measurements were performed. Total body water (TBW), fat-mass (FM), fat-free mass (FFM), body cell mass (BCM) and extra-cellular water (ECW) were estimated using conventional BIA regression equations. The resistance-reactance graph (RXc graph) method was used for vector BIA using as reference population the set of 353 children with BMI 14.0-21.5kg/m(2). RESULTS: Mean vector displacement followed a definite pattern, with progressive vector shortening in groups with increasing BMI class, and along a fixed phase angle. This pattern indicates an increase in TBW due to an increase in soft tissue mass with an average, normal hydration. In NW children, vectors out of the right and upper half of the 75% tolerance ellipse indicating leanness, and vectors falling out of the right and lower half of the tolerance ellipse indicating undernutrition, show a significantly reduced value of BCM but no significant differences in FM or triceps skinfold thickness (TST), respectively, compared to vectors falling within the 75% tolerance ellipse. CONCLUSIONS: Although BMI is a reliable measure to grade overweight, it cannot differentiate whether weight change is due to variation of FM, FFM or water. In our study a different impedance vector pattern has been associated with normal weight to obesity, and we have established the trajectory followed by the impedance vector of standardized age, healthy children grouped by BMI. This BIVA may be useful for clinical purposes due to ability to detect changes in hydration or body composition in children.
- Published
- 2006
4. Body mass index and skinfold thickness versus bioimpedance analysis: fat mass prediction in children
- Author
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S Principato, Claudio Falconi, Angelo Pietrobelli, Marco Caroli, Rossella Trio, Bruna Guida, Pierluigi Pecoraro, Pecoraro, P, Guida, Bruna, Caroli, M, Trio, R, Falconi, Claudio, Principato, S, and Pietrobelli, A.
- Subjects
Male ,medicine.medical_specialty ,Pediatrics ,Endocrinology, Diabetes and Metabolism ,Body adiposity index ,Body composition ,Childhood obesity ,Body Mass Index ,Cohort Studies ,Endocrinology ,Classification of obesity ,Internal medicine ,Linear regression ,Internal Medicine ,medicine ,Electric Impedance ,Humans ,Obesity ,Child ,Pediatric ,Body volume index ,business.industry ,Reproducibility of Results ,General Medicine ,medicine.disease ,Skinfold thickne ,Skinfold Thickness ,Adipose Tissue ,Female ,Italy ,Bioimpedance analysi ,business ,Body mass index ,Cohort study - Abstract
Childhood obesity increases the risk of morbidity whether or not obesity persists into adulthood. Measurement of body fat content using bioimpedance analysis (BIA) is a useful tool in epidemiologic studies. Both tricep skinfold thickness (TST, mm) and body mass index (BMI, kg/m(2)) are indirect, simple methods and easy to perform for assessing body composition. These methods are generally accepted as good clinical measures for defining childhood obesity. The aim of our study was to evaluate fat mass (FM, kg and %) measurements using TST and BIA (50 kHz) in a cohort of 6-year-old Italian children. A total of 228 southern Italian children (121 boys, 107 girls), randomly selected in nine local primary schools, were included in the study. The correlation between methods for measuring FM was calculated. Linear regression analysis showed a significant positive correlation between FM measured with BIA and BMI ( r=0.92, p
- Published
- 2003
5. Impact of Protein Nanoparticle Shape on the Immunogenicity of Antimicrobial Glycoconjugate Vaccines.
- Author
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Dolce M, Proietti D, Principato S, Giusti F, Adamo GM, Favaron S, Ferri E, Margarit I, Romano MR, Scarselli M, and Carboni F
- Subjects
- Animals, Mice, Glycoconjugates, Ferritins, Oligosaccharides, Anti-Infective Agents, Nanoparticles
- Abstract
Protein self-assembling nanoparticles (NPs) can be used as carriers for antigen delivery to increase vaccine immunogenicity. NPs mimic the majority of invading pathogens, inducing a robust adaptive immune response and long-lasting protective immunity. In this context, we investigated the potential of NPs of different sizes and shapes-ring-, rod-like, and spherical particles-as carriers for bacterial oligosaccharides by evaluating in murine models the role of these parameters on the immune response. Oligosaccharides from Neisseria meningitidis type W capsular polysaccharide were conjugated to ring-shape or nanotubes of engineered Pseudomonas aeruginosa Hemolysin-corregulated protein 1 (Hcp1cc) and to spherical Helicobacter pylori ferritin. Glycoconjugated NPs were characterized using advanced technologies such as High-Performance Liquid Chromatography (HPLC), Asymmetric Flow-Field Flow fractionation (AF4), and Transmission electron microscopy (TEM) to verify their correct assembly, dimensions, and glycosylation degrees. Our results showed that spherical ferritin was able to induce the highest immune response in mice against the saccharide antigen compared to the other glycoconjugate NPs, with increased bactericidal activity compared to benchmark MenW-CRM
197 . We conclude that shape is a key attribute over size to be considered for glycoconjugate vaccine development.- Published
- 2024
- Full Text
- View/download PDF
6. Effects of Chemical Insecticide Residues and Household Surface Type on a Beauveria bassiana- Based Biopesticide (Aprehend ® ) for Bed Bug Management.
- Author
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Shikano I, Bellicanta GS, Principato S, and Jenkins NE
- Abstract
The biopesticide Aprehend, containing spores of the entomopathogenic fungus Beauveria bassiana , is a biological control agent for the management of the common bed bug ( Cimex lectularius L.) (Hemiptera: Cimicidae). The spores are applied in strategically placed barriers, which bed bugs walk across as they search for a bloodmeal. Application of chemical insecticides by the general public and professional pest managers is common, which means that Aprehend may be sprayed on existing insecticide residues. We evaluated the effect of chemical residues, of 22 different chemical insecticides on different household surface types. We found that residues from 12 chemical pesticides significantly reduced spore viability measured 5 weeks after application in comparison to the control. However, efficacy of Aprehend, as measured by bed bug mortality and mean survival time after exposure to sprayed surfaces, seven weeks after application was not impacted detrimentally. Furthermore, in some cases, efficacy of old chemical residues was enhanced by the combination of chemical and Aprehend seven weeks after application. Surface type also played a role in the relative efficacy of all products and combinations, particularly as the residues aged.
- Published
- 2021
- Full Text
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7. Synergistic Activity of Colistin in Combination With Resveratrol Against Colistin-Resistant Gram-Negative Pathogens.
- Author
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Cannatelli A, Principato S, Colavecchio OL, Pallecchi L, and Rossolini GM
- Abstract
Objectives: In this study, we investigated the antimicrobial activity of resveratrol in combination with colistin, a last-resort agent for the treatment of severe infections caused by multidrug resistant Gram-negative pathogens. Methods: The synergistic activity and the bactericidal activity of colistin in combination with resveratrol was investigated by checkerboard assays and time-kill assays, respectively. A total of 21 strains were investigated, including 16 strains of different species ( Klebsiella pneumoniae, n = 6, Escherichia coli, n = 6; Citrobacter braakii, n = 1; Stenotrophomonas malthophilia, n = 1; Enterobacter cloaceae, n = 1 ; Acinetobacter baumannii, n = 1) with acquired colistin resistance, three colistin-susceptible K. pneumoniae precursors, and two strains of intrinsically colistin-resistant species ( Serratia marcescens, n = 1; Proteus mirabilis, n = 1). Mechanisms of acquired colistin resistance included chromosomal mutations (i.e., mgrB, pmrAB ) and plasmid genes ( mcr-1, mcr-1 .2). Results: Resveratrol did not show any significant intrinsic antimicrobial activity. Overall, a relevant synergistic antimicrobial activity of resveratrol in combination with colistin was observed with all tested strains, except for the three colistin-susceptible K. pneumoniae strains, and for two mcr-1 -positive E. coli strains. In time-kill assays, performed with 15 selected strains, the combination of colistin 2 mg/L plus resveratrol 128 mg/L was bactericidal with 11 strains, and bacteriostatic for the remaining ones. Conclusions: Resveratrol was found to potentiate colistin activity against a wide panel of colistin-resistant strains, regardless of species and resistance mechanisms, which would deserve further investigation for potential clinical applications.
- Published
- 2018
- Full Text
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8. Alistag TM , a new coating agent for aging cheese and hams.
- Author
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Principato MA, Cascone S, Goga BTC, Moretta I, and Principato S
- Abstract
Aging rooms of dry-cured ham and cheese are subject to the development of mold and arthropods, above all mites, which cause the erosion of the external part of these food products, reducing their surface to dust and determining their progressive degradation. This work is meant to give the results of an experiment carried out to test the level of protection supplied by Alistag
TM , a coating agent based on Gluconodeltalactone, on a typical Sicilian cheese cosacavaddu ibleo . AlistagTM was applied by nebulization and by immersion. The two parameters took in consideration to evaluate their efficacy were the presence/absence of cracks and the level of dustiness on the surface of the cheese. AlistagTM turned out to be very efficient in protecting cheese both from the development of dust and from cracks; between the two kinds of application tested, immersion resulted to be the best one, for the protecting action lasts longer., Competing Interests: Conflict of interest: the authors declare no potential conflict of interest.- Published
- 2018
- Full Text
- View/download PDF
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