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2. Codesigning a supportive online resource for Australian cancer carers: a thematic analysis of informal carers’ and healthcare professionals’ perspectives about carers’ responsibilities and content needs

Author

Perera, Sharnel Miriam, primary, O’Callaghan, Clare, additional, Ugalde, Anna, additional, Santin, Olinda, additional, Beer, Cassandra, additional, Prue, G, additional, Lane, Katherine, additional, Hanna, Gerard G, additional, and Schofield, Penelope, additional

Published
2021
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3. A Comparison of Adolescent versus Young Adult Outpatients with First-Presentation Borderline Personality Disorder: Findings from the MOBY Randomized Controlled Trial

Author

Chanen, Andrew M., primary, Betts, Jennifer K., additional, Jackson, Henry, additional, Cotton, Sue M., additional, Gleeson, John, additional, Davey, Christopher G., additional, Thompson, Katherine, additional, Perera, Sharnel, additional, Rayner, Victoria, additional, Chong, Sinn Yuin, additional, and McCutcheon, Louise, additional

Published
2021
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4. A Comparison of Adolescent versus Young Adult Outpatients with First-Presentation Borderline Personality Disorder: Findings from the MOBY Randomized Controlled Trial.

Author

Chanen, Andrew M., Betts, Jennifer K., Jackson, Henry, Cotton, Sue M., Gleeson, John, Davey, Christopher G., Thompson, Katherine, Perera, Sharnel, Rayner, Victoria, Chong, Sinn Yuin, and McCutcheon, Louise

Subjects
BORDERLINE personality disorder, PERSONALITY disorders, TEENAGERS, YOUNG adults, CLINICAL trials
Abstract

Copyright of Canadian Journal of Psychiatry is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022
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5. Comorbid externalising behaviour in AD/HD: Evidence for a distinct pathological entity in adolescence

Author

Perera, Sharnel, Crewther, David, Croft, Rodney, Keage, Hannah, Hermens, Daniel, Clark, C Richard, Perera, Sharnel, Crewther, David, Croft, Rodney, Keage, Hannah, Hermens, Daniel, and Clark, C Richard

Abstract

While the profiling of subtypes of Attention Deficit Hyperactivity Disorder (AD/HD) have been the subject of considerable scrutiny, both psychometrically and psychophysiologically, little attention has been paid to the effect of diagnoses comorbid with AD/HD on such profiles. This is despite the greater than 80% prevalence of comorbidity under the DSM-IV-TR diagnostic definitions. Here we investigate the event related potential (ERP) and psychometric profiles of Controls, AD/HD, and comorbid AD/HD (particularly AD/HD+ODD/CD) groups on six neurocognitive tasks thought to probe the constructs of selective and sustained attention, response inhibition and executive function. Data from 29 parameters extracted from a child group (age range 6 to 12; 52 Controls and 64 AD/HD) and from an adolescent group (age range 13 to 17; 79 Controls and 88 AD/HD) were reduced via a Principal Components Analysis, the 6 significant eigenvectors then used as determinants of cluster membership via a Two-Step Cluster Analysis. Two clusters were found in the analysis of the adolescent age group - a cluster dominated by Control and AD/HD participants without comorbidity, while the second cluster was dominated by AD/HD participants with externalising comorbidity (largely oppositional defiant/conduct disorder ODD/CD). A similar segregation within the child age group was not found. Further analysis of these objectively determined clusters in terms of their clinical diagnoses indicates a significant effect of ODD/CD comorbidity on a concurrent AD/HD diagnosis. We conclude that comorbid externalising behaviour in AD/HD constitutes a distinct pathological entity in adolescence.

Published
2012

7. Comorbid externalising behaviour in AD/HD : evidence for a distinct pathological entity in adolescence

Author

Daniel F. Hermens, Sharnel Perera, Hannah A.D. Keage, C. Richard Clark, Rodney J. Croft, David P. Crewther, Perera, Sharnel, Crewther, David, Croft, Rodney, Keage, Hannah, Hermens, Daniel, and Clark, C Richard

Subjects
Male, Anatomy and Physiology, age distribution, Psychometrics, Child Behavior, Comorbidity, Social and Behavioral Sciences, preschool child, Cognition, Cluster Analysis, Psychology, Child, Evoked Potentials, Psychiatry, Principal Component Analysis, child, Multidisciplinary, article, behavior disorder, Anxiety Disorders, Electrophysiology, Mental Health, Conduct disorder, Attention Deficit and Disruptive Behavior Disorders, Medicine, Research Article, Conduct Disorder, medicine.medical_specialty, Adolescent, Science, Cognitive Neuroscience, attention deficit disorder, Neuropsychiatric Disorders, Biology, Adolescent age, Personality Disorders, male, mental disorders, medicine, Attention deficit hyperactivity disorder, Humans, Pathological, Behavior, Case-control study, Australia, Cognitive Psychology, medicine.disease, major clinical study, Adolescent Behavior, Attention Deficit Disorder with Hyperactivity, Case-Control Studies, adolescent, adolescence, Attention (Behavior), Neurocognitive, Neuroscience, cluster analysis
Abstract

While the profiling of subtypes of Attention Deficit Hyperactivity Disorder (AD/HD) have been the subject of considerable scrutiny, both psychometrically and psychophysiologically, little attention has been paid to the effect of diagnoses comorbid with AD/HD on such profiles. This is despite the greater than 80% prevalence of comorbidity under the DSM-IV-TR diagnostic definitions. Here we investigate the event related potential (ERP) and psychometric profiles of Controls, AD/HD, and comorbid AD/HD (particularly AD/HD+ODD/CD) groups on six neurocognitive tasks thought to probe the constructs of selective and sustained attention, response inhibition and executive function. Data from 29 parameters extracted from a child group (age range 6 to 12; 52 Controls and 64 AD/HD) and from an adolescent group (age range 13 to 17; 79 Controls and 88 AD/HD) were reduced via a Principal Components Analysis, the 6 significant eigenvectors then used as determinants of cluster membership via a Two-Step Cluster Analysis. Two clusters were found in the analysis of the adolescent age group - a cluster dominated by Control and AD/HD participants without comorbidity, while the second cluster was dominated by AD/HD participants with externalising comorbidity (largely oppositional defiant/conduct disorder ODD/CD). A similar segregation within the child age group was not found. Further analysis of these objectively determined clusters in terms of their clinical diagnoses indicates a significant effect of ODD/CD comorbidity on a concurrent AD/HD diagnosis. We conclude that comorbid externalising behaviour in AD/HD constitutes a distinct pathological entity in adolescence. Refereed/Peer-reviewed

Published
2012

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