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8. 2021 Interim Guidance to Health Care Providers for Basic and Advanced Cardiac Life Support in Adults, Children, and Neonates With Suspected or Confirmed COVID-19

Author

Hsu, Antony, Sasson, Comilla, Kudenchuk, Peter J., Atkins, Dianne L., Aziz, Khalid, Becker, Lance B., Berg, Robert A., Bhanji, Farhan, Bradley, Steven M., Brooks, Steven C., Chan, Melissa, Chan, Paul S., Cheng, Adam, Clemency, Brian M., de Caen, Allan, Duff, Jonathan P., Edelson, Dana P., Flores, Gustavo E., Fuchs, Susan, Girotra, Saket, Hinkson, Carl, Joyner, Benny L., Jr, Kamath-Rayne, Beena D., Kleinman, Monica, Lasa, Javier J., Lavonas, Eric J., Lee, Henry C., Lehotzky, Rebecca E., Levy, Arielle, Mancini, Mary E., McBride, Mary E., Meckler, Garth, Merchant, Raina M., Moitra, Vivek K., Morgan, Ryan W., Nadkarni, Vinay, Panchal, Ashish R., Peberdy, Mary Ann, Raymond, Tia, Roberts, Kathryn, Sayre, Michael R., Schexnayder, Stephen M., Sutton, Robert M., Terry, Mark, Walsh, Brian, Wang, David S., Zelop, Carolyn M., and Topjian, Alexis

Published
2021
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9. Trends in Survival After In-Hospital Cardiac Arrest During Nights and Weekends

Author

Abella, Benjamin, Anderson, Monique L., Bradley, Steven M., Chan, Paul S., Edelson, Dana P., Churpek, Matthew M., Geocadin, Romergryko, Goldberger, Zachary D., Howard, Patricia K., Kurz, Michael C., Mosesso, Vincent N., Jr., Nassar, Boulos, Ornato, Joseph P., Peberdy, Mary Ann, Perman, Sarah M., Ofoma, Uchenna R., Basnet, Suresh, Berger, Andrea, Kirchner, H. Lester, and Girotra, Saket

Published
2018
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10. Part 7: Systems of Care: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care

Author

Berg, Katherine M., Cheng, Adam, Panchal, Ashish R., Topjian, Alexis A., Aziz, Khalid, Bhanji, Farhan, Bigham, Blair L., Hirsch, Karen G., Hoover, Amber V., Kurz, Michael C., Levy, Arielle, Lin, Yiqun, Magid, David J., Mahgoub, Melissa, Peberdy, Mary Ann, Rodriguez, Amber J., Sasson, Comilla, and Lavonas, Eric J.

Published
2020
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11. Part 3: Adult Basic and Advanced Life Support: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care

Author

Panchal, Ashish R., Bartos, Jason A., Cabañas, José G., Donnino, Michael W., Drennan, Ian R., Hirsch, Karen G., Kudenchuk, Peter J., Kurz, Michael C., Lavonas, Eric J., Morley, Peter T., O’Neil, Brian J., Peberdy, Mary Ann, Rittenberger, Jon C., Rodriguez, Amber J., Sawyer, Kelly N., and Berg, Katherine M.

Published
2020
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12. Interim Guidance for Basic and Advanced Life Support in Adults, Children, and Neonates With Suspected or Confirmed COVID-19: From the Emergency Cardiovascular Care Committee and Get With The Guidelines-Resuscitation Adult and Pediatric Task Forces of the American Heart Association

Author

Edelson, Dana P., Sasson, Comilla, Chan, Paul S., Atkins, Dianne L., Aziz, Khalid, Becker, Lance B., Berg, Robert A., Bradley, Steven M., Brooks, Steven C., Cheng, Adam, Escobedo, Marilyn, Flores, Gustavo E., Girotra, Saket, Hsu, Antony, Kamath-Rayne, Beena D., Lee, Henry C., Lehotsky, Rebecca E., Mancini, Mary E., Merchant, Raina M., Nadkarni, Vinay M., Panchal, Ashish R., Peberdy, Mary Ann R., Raymond, Tia T., Walsh, Brian, Wang, David S., Zelop, Carolyn M., and Topjian, Alexis A.

Published
2020
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27. Effects of Methylprednisolone on Myocardial Function and Microcirculation in Post-resuscitation: A Rat Model

Author

Wang, Changsheng, primary, Bischof, Evelyne, additional, Xu, Jing, additional, Guo, Qinyue, additional, Zheng, Guanghui, additional, Ge, Weiwei, additional, Hu, Juntao, additional, Georgescu Margarint, Elena Laura, additional, Bradley, Jennifer L., additional, Peberdy, Mary Ann, additional, Ornato, Joseph P., additional, Zhu, Changqing, additional, and Tang, Wanchun, additional

Published
2022
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30. UAMC-3203 or/and Deferoxamine Improve Post-Resuscitation Myocardial Dysfunction Through Suppressing Ferroptosis in a Rat Model of Cardiac Arrest

Author

Jin, Tao, primary, He, Qing, additional, Cheng, Cheng, additional, Li, Hui, additional, Liang, Lian, additional, Zhang, Guozhen, additional, Su, Chenglei, additional, Xiao, Yan, additional, Bradley, Jennifer, additional, Peberdy, Mary Ann, additional, Ornato, Joseph P., additional, and Tang, Wanchun, additional

Published
2021
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31. Age-dependent trends in survival after adult in-hospital cardiac arrest

Author

Wiberg, Sebastian, Holmberg, Mathias J., Donnino, Michael W., Kjaergaard, Jesper, Hassager, Christian, Witten, Lise, Berg, Katherine M., Moskowitz, Ari, Andersen, Lars W., Grossestreuer, Anne, Edelson, Dana, Ornato, Joseph, Peberdy, Mary Ann, Churpek, Matthew, Kurz, Michael, Starks, Monique Anderson, Chan, Paul, Girotra, Saket, Perman, Sarah, Goldberger, Zachary, Wiberg, Sebastian, Holmberg, Mathias J., Donnino, Michael W., Kjaergaard, Jesper, Hassager, Christian, Witten, Lise, Berg, Katherine M., Moskowitz, Ari, Andersen, Lars W., Grossestreuer, Anne, Edelson, Dana, Ornato, Joseph, Peberdy, Mary Ann, Churpek, Matthew, Kurz, Michael, Starks, Monique Anderson, Chan, Paul, Girotra, Saket, Perman, Sarah, and Goldberger, Zachary

Abstract

Background: While survival after in-hospital cardiac arrest (IHCA) has improved in recent years, it remains unknown whether this trend primarily applies to younger IHCA victims. The aim of this study was to assess trends in survival to hospital discharge after adult IHCA across age groups from 2000 to 2016. Methods: This is an observational study of IHCA patients included in the Get With The Guidelines®-Resuscitation registry between 2000 and 2016. The primary outcome was survival to hospital discharge. Patients were stratified into five age groups: <50 years, 50–59 years, 60–69 years, 70–79 years, and ≥80 years. Generalized linear regression was used to obtain absolute survival rates over time. Results: A total of 234,767 IHCA patients were included. The absolute increase in survival per calendar year was 0.8% (95% CI 0.7–1.0%, p < 0.001) for patients younger than 50 years, 0.6% (95% CI 0.4–0.7%, p < 0.001) for patients between 50 and 59 years, 0.5% (95% CI 0.4–0.6%, p < 0.001) for patients between 60 and 69 years, 0.5% (95% CI 0.4–0.6%, p < 0.001) for patients between 70 and 79 years, and 0.5% (95% CI 0.4–0.6%, p < 0.001) for patients older than 80 years. We observed a significant interaction between calendar year and age group (p < 0.001), indicating that the rate of improvement in survival over time was significantly different between age groups. Conclusions: For patients with IHCA, rates of survival to discharge have improved significantly from 2000 to 2016 across all age groups.

Published
2020

32. Epinephrine before defibrillation in patients with shockable in-hospital cardiac arrest: propensity matched analysis

Author

Evans, Erin, Swanson, Morgan B, Mohr, Nicholas, Boulos, Nassar, Vaughan-Sarrazin, Mary, Chan, Paul S, Girotra, Saket, Grossestreuer, Anne, Moskowitz, Ari, Edelson, Dana, Ornato, Joseph, Peberdy, Mary Ann, Churpek, Matthew, Kurz, Michael, Anderson Starks, Monique, Perman, Sarah, and Goldberger, Zachary

Subjects
Adult, Male, Resuscitation, medicine.medical_specialty, Time Factors, Epinephrine, Defibrillation, medicine.medical_treatment, Electric Countershock, Return of spontaneous circulation, Internal medicine, medicine, Humans, Registries, Myocardial infarction, Propensity Score, Mechanical ventilation, business.industry, Research, Arrhythmias, Cardiac, General Medicine, medicine.disease, Patient Discharge, Heart Arrest, Treatment Outcome, Heart failure, Propensity score matching, Cardiology, Female, business, medicine.drug
Abstract

ObjectiveTo determine the use of epinephrine (adrenaline) before defibrillation for treatment of in-hospital cardiac arrest due to a ventricular arrhythmia and examine its association with patient survival.DesignPropensity matched analysis.Setting2000-18 data from 497 hospitals participating in the American Heart Association’s Get With The Guidelines-Resuscitation registry.ParticipantsAdults aged 18 and older with an index in-hospital cardiac arrest due to an initial shockable rhythm treated with defibrillation.InterventionsAdministration of epinephrine before first defibrillation.Main outcome measuresSurvival to discharge; favorable neurological survival, defined as survival to discharge with none, mild, or moderate neurological disability measured using cerebral performance category scores; and survival after acute resuscitation (that is, return of spontaneous circulation for >20 minutes). A time dependent, propensity matched analysis was performed to adjust for confounding due to indication and evaluate the independent association of epinephrine before defibrillation with study outcomes.ResultsAmong 34 820 patients with an initial shockable rhythm, 7054 (20.3%) were treated with epinephrine before defibrillation, contrary to current guidelines. In comparison with participants treated with defibrillation first, participants receiving epinephrine first were less likely to have a history of myocardial infarction or heart failure, but more likely to have renal failure, sepsis, respiratory insufficiency, and receive mechanical ventilation before in-hospital cardiac arrest (standardized differences >10% for all). Treatment with epinephrine before defibrillation was strongly associated with delayed defibrillation (median 4 minutesv0 minutes). In propensity matched analysis (6569 matched pairs), epinephrine before defibrillation was associated with lower odds of survival to discharge (22.4%v29.7%; adjusted odds ratio 0.69; 95% confidence interval 0.64 to 0.74; Pv21.6%; 0.68; 0.61 to 0.76; Pv69.5%; 0.73; 0.67 to 0.79; PConclusionsContrary to current guidelines that prioritize immediate defibrillation for in-hospital cardiac arrest due to a shockable rhythm, one in five patients are treated with epinephrine before defibrillation. Use of epinephrine before defibrillation was associated with worse survival outcomes.

Published
2021

34. Abstract 142: Combined Therapy with Polyethylene Glycol-20k and MCC950 Preserves Post-resuscitation Myocardial Mitochondrial Function in a Rat Model of Cardiac Arrest and Cardiopulmonary Resuscitation

Author

Liang, Lian, primary, Zhang, Guozhen, additional, Li, Hui, additional, Cheng, Cheng, additional, Jin, Tao, additional, Su, Chengli, additional, xiao, yan, additional, Bradley, Jennifer, additional, Fyffe-Freil, Ria, additional, Peberdy, Mary Ann A, additional, Ornato, Joseph P, additional, Mangino, Martin, additional, and Tang, Wanchun, additional

Published
2020
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36. Abstract 140: Effects of ω-3 Polyunsaturated Fatty Acids on Systemic Inflammation and Post-resuscitation Myocardial Function in a Rat Model of Cardiac Arrest and Cardiopulmonary Resuscitation

Author

Cheng, Cheng, primary, Li, Hui, additional, Jin, Tao, additional, Liang, Lian, additional, Zhang, Guozhen, additional, Bradley, Jennifer, additional, Peberdy, Mary Ann A, additional, Ornato, Joseph P, additional, Wijesinghe, Dayanjan, additional, and Tang, Wanchun, additional

Published
2020
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37. Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial

Author

Maggioni, Aldo P., Greene, Stephen J., Fonarow, Gregg C., Böhm, Michael, Zannad, Faiez, Solomon, Scott D., Lewis, Eldrin F., Baschiera, Fabio, Hua, Tsushung A., Gimpelewicz, Claudio R., Lesogor, Anastasia, Gheorghiade, Mihai, Ramos, Silvina, Luna, Alejandra, Miriuka, Santiago, Diez, Mirta, Perna, Eduardo, Luquez, Hugo, Pinna, Jorge Garcia, Castagnino, Jorge, Alvarenga, Pablo, Ibañez, Julio, Blumberg, Eduardo Salmon, Dizeo, Claudio, Guerrero, Rodolfo Ahuad, Schygiel, Pablo, Milesi, Rodolfo, Sosa, Carlos, Hominal, Miguel, Marquez, Lilia Lobo, Poy, Carlos, Hasbani, Eduardo, Vico, Marisa, Fernandez, Alberto, Vita, Nestor, Vanhaecke, Johan, De Keulenaer, Gilles, Striekwold, Harry, Vervoort, Geert, Vrolix, Mathias, Henry, Philippe, Dendale, Paul, Smolders, Walter, Marechal, Patrick, Vandekerckhove, Hans, Oliveira, Mucio, Jr., Neuenschwande, Fernando, Reis, Gilmar, Saraiva, Jose, Bodanese, Luiz, Canesin, Manoel, Greco, Oswaldo, Bassan, Roberto, Marino, Roberto Luis, Giannetti, Nadia, Moe, Gordon, Sussex, Bruce, Sheppard, Richard, Huynh, Thao, Stewart, Robert, Haddad, Haissam, Echeverria, Luis, Quintero, Adalberto, Torres, Adriana, Jaramillo, Mónica, Lopez, Mónica, Mendoza, Fernan, Florez, Noel, Cotes, Carlos, Garcia, Magali, Belohlavek, Jan, Hradec, Jaromir, Peterka, Martin, Gregor, Pavel, Monhart, Zdenek, Jansky, Petr, Kettner, Jiri, Reichert, Petr, Spinar, Jindrich, Brabec, Tomas, Hutyra, Martin, Solar, Miroslav, Pietilä, Mikko, Nyman, Kai, Pajari, Risto, Cohen, Ariel, Galinier, Michel, Gosse, Philippe, Livarek, Bernard, Neuder, Yannick, Jourdain, Patrick, Picard, François, Isnard, Richard, Hoppe, Uta, Kaeaeb, Stefan, Rosocha, Stefan, Prondzinsky, Roland, Felix, Stephan, Duengen, Hans-Dirk, Figulla, Hans-Reiner, Fischer, Sven, Behrens, Steffen, Stawowy, Philipp, Kruells-Muench, Juergen, Knebel, Fabian, Nienaber, Christoph, Werner, Dierk, Aron, Wilma, Remppis, Bjoern, Hambrecht, Rainer, Kisters, Klaus, Werner, Nikos, Hoffmann, Stefan, Rossol, Siegbert, Geiss, Ernst, Graf, Kristof, Hamann, Frank, von Scheidt, Wolfgang, Schwinger, Robert, Tebbe, Ulrich, Costard-Jaeckle, Angelika, Lueders, Stephan, Heitzer, Thomas, Leutermann-Oei, Marie-Louise, Braun-Dullaeus, Ruediger, Roehnisch, Jens-Uwe, Muth, Gerhard, Goette, Andreas, Rotter, Achim, Ebelt, Henning, Olbrich, Hans-Georg, Mitrovic, Veselin, Hengstenberg, Christian, Schellong, Sebastian, Zamolyi, Karoly, Vertes, Andras, Matoltsy, Andras, Palinkas, Attila, Herczeg, Bela, Apro, Dezso, Lupkovics, Geza, Tomcsanyi, Janos, Toth, Kalman, Mathur, Atul, Banker, Darshan, Bharani, Anil, Arneja, Jaspal, Khan, Aziz, Gadkari, Milind, Hiremath, Jagdish, Patki, Nitin, Kumbla, Makund, Santosh, M.J., Ravikishore, A.G., Abhaichand, Rajpal, Maniyal, Vijayakukmar, Nanjappa, Manjunath, Reddy, P. Naveen, Chockalingam, Kulasekaran, Premchand, Rajendra, Mahajan, Vijay, Lewis, Basil, Wexler, Dov, Shochat, Michael, Keren, Andre, Omary, Muhamad, Katz, Amos, Marmor, Alon, Lembo, Giuseppe, Di Somma, Salvatore, Boccanelli, Alessandro, Barbiero, Mario, Pajes, Giuseppe, De Servi, Stefano, Greco, Dott Cosimo, De Santis, Fernando, Floresta, Agata, Visconti, Luigi Oltrona, Piovaccari, Giancarlo, Cavallini, Claudio, Di Biase, Matteo, Masini, Dott Franco, Vassanelli, Corrado, Viecca, Maurizio, Cangemi, Dott Francesco, Pirelli, Salvatore, Borghi, Claudio, Volpe, Massimo, Branzi, Angelo, Percoco, Dott Giovanni, Severi, Silvia, Santini, Alberto, De Lorenzi, Ettore, Metra, Marco, Zacà, Valerio, Mortara, Andrea, Tranquilino, Francisco P., Babilonia, Noe A., Ferrolino, Arthur M., Manlutac, Benjamin, Jr, Dluzniewski, Miroslaw, Dzielinska, Zofia, Nowalany-Kozie, Ewa, Mazurek, Walentyna, Wierzchowiecki, Jerzy, Wysokinski, Andrzej, Szachniewicz, Joanna, Romanowski, Witold, Krauze-Wielicka, Magdalena, Jankowski, Piotr, Berkowski, Piotr, Szelemej, Roman, Kleinrok, Andrzej, Kornacewicz-Jac, Zdzislawa, Vintila, Marius, Vladoianu, Mircea, Militaru, Constantin, Dan, Gheorghe, Dorobantu, Maria, Dragulescu, Stefan, Kostenko, Victor, Vishnevsky, Alexandr, Goloschekin, Boris, Tyrenko, Vadim, Gordienko, Alexander, Kislyak, Oxana, Martsevich, Sergey, Kuchmin, Alexey, Karpov, Yurii, Fomin, Igor, Shvarts, Yury, Orlikova, Olga, Ershova, Olga, Berkovich, Olga, Sitnikova, Maria, Pakhomova, Inna, Boldueva, Svetlana, Tyurina, Tatiana, Simanenkov, Vladimir, Boyarkin, Mikhail, Novikova, Nina, Tereschenko, Sergey, Zadionchenko, Vladimir, Shogenov, Zaur, Gordeev, Ivan, Moiseev, Valentin, Wong, Raymond, Ong, Hean Yee, Le Tan, Ju, Goncalvesova, Eva, Kovar, Frantisek, Skalina, Ivan, Kasperova, Viera, Hojerova, Silvia, Szentivanyi, Miroslav, Stancak, Branislav, Babcak, Marian, Kycina, Peter, Poliacik, Pavol, Toth, Peter, Sirotiakova, Jana, de Sa, Esteban Lopez, Bueno, Manuel Gomez, Selles, Manuel Martinez, Cabrera, Jose Angel, Freire, Ramon Bover, Gonzalez Juanatey, Jose Ramon, Comin, Josep, Soriano, FranciscoRidocci, Lopez, Alejandro, Vicho, Raul, Lama, Manuel Geraldia, Schaufelberger, Maria, Brunotte, Richard, Ullman, Bengt, Hagerman, Inger, Cizinsky, Stella, Cherng, Wen-Jin, Yu, Wen-Chung, Kuo, Chi-Tai, Chang, Kuan-Cheng, Lai, Wen-Ter, Kuo, Jen-Yuan, Ural, Dilek, Badak, Ozer, Akin, Mustafa, Yigit, Zerrin, Yokusoglu, Mehmet, Yilmaz, Mehmet, Abaci, Adnan, Ebinc, Haksun, Perlman, Richard, Parish, David, Bergin, James, Burnham, Kenneth, Brown, Christopher, Lundbye, Justin, Williams, Celeste, Eisen, Howard, Juneman, Elizabeth, Joseph, Susan, Peberdy, Mary Ann, Peura, Jennifer, Gupta, Vishal, Habet, Kalim, French, William, Mody, Freny, Graham, Susan, Hazelrigg, Monica, Chung, Eugene, Dunlap, Stephanie, Nikolaidis, Lazaros, Najjar, Samer, Katz, Richard, Murali, Srinivas, Izzo, Joseph L., Callister, Tracy, Phillips, Roland, Lippolis, Nicholas, Winterton, John, Meymandi, Sheba, Heilman, Karl, III, Oren, Ron, Zolty, Ronald, Brottman, Michael, Gunawardena, D.R., Adams, Kirkwood, Barnard, Denise, Klapholz, Marc, and Fulmer, James

Published
2013
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38. ST-Segment Elevation Myocardial Infarction: Recommendations on Triage of Patients to Heart Attack Centers: Is it Time for a National Policy for the Treatment of ST-Segment Elevation Myocardial Infarction?

Author

Henry, Timothy D., Atkins, James M., Cunningham, Michael S., Francis, Gary S., Groh, William J., Hong, Robert A., Kern, Karl B., Larson, David M., Ohman, Erik Magnus, Ornato, Joseph P., Peberdy, Mary Ann, Rosenberg, Michael J., and Weaver, W. Douglas

Published
2006
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40. Do Sex Differences Exist in the Establishment of “Do Not Attempt Resuscitation” Orders and Survival in Patients Successfully Resuscitated From In‐Hospital Cardiac Arrest?

Author

Perman, Sarah M., primary, Beaty, Brenda L., additional, Daugherty, Stacie L., additional, Havranek, Edward P., additional, Haukoos, Jason S., additional, Juarez‐Colunga, Elizabeth, additional, Bradley, Steven M., additional, Fendler, Timothy J., additional, Chan, Paul S., additional, Grossestreuer, Anne V., additional, Moskowitz, Ari, additional, Edelson, Dana, additional, Ornato, Joseph, additional, Berg, Katherine, additional, Peberdy, Mary Ann, additional, Churpek, Matthew, additional, Kurz, Michael, additional, Starks, Monique Anderson, additional, Girotra, Saket, additional, and Goldberger, Zachary, additional

Published
2020
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43. Abstract 21: Effects of the Selective NLRP3-Inflammasome Inhibitor MCC950 on Post-Resuscitation Myocardial and Cerebral Function in a Rat Model of Cardiopulmonary Resuscitation

Author

Zheng, Guanghui, primary, Xu, Jing, additional, He, Fenglian, additional, Hu, Juntao, additional, Ge, Weiwei, additional, Ji, Xianfei, additional, Bradley, Jennifer, additional, Peberdy, Mary Ann A, additional, Ornato, Joseph P, additional, Jiang, Longyuan, additional, Wang, Tong, additional, Toldo, Stefano, additional, and Tang, Wanchun, additional

Published
2019
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44. Abstract 174: Effects of Melatonin (N-Acetyl-5-Methoxytryptamine) on Inflammation and Cerebral Microcirculation After Cardiopulmonary Resuscitation in a Rat Model of Cardiac Arrest

Author

Hu, Juntao, primary, Zheng, Guanghui, additional, He, Fenglian, additional, Ge, Weiwei, additional, Xu, Jing, additional, Ji, Xianfei, additional, Bradley, Jennifer, additional, Peberdy, Mary Ann A, additional, Ornato, Joseph P, additional, and Tang, Wanchun, additional

Published
2019
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47. Abstract 194: Effects of PEG-20k on Coronary Perfusion Pressure and Post-Resuscitation Myocardial and Cerebral Function in a Rat Model of Cardiac Arrest

Author

Ge, Weiwei, primary, Moore, Christine, additional, Zheng, Guanghui, additional, Ji, Xianfei, additional, He, Fenglian, additional, Hu, Juntao, additional, Bradley, Jennifer, additional, Peberdy, Mary Ann A, additional, Ornato, Joseph P, additional, Mangino, Martin, additional, and Tang, Wanchun, additional

Published
2019
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