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1. Logistica e Supply Chain per non addetti ai lavori

Author

Palumbo, Michele, Belvedere, Valeria, Di Pietro, M., Palumbo M., Belvedere V. (ORCID:0000-0002-7748-5152), Palumbo, Michele, Belvedere, Valeria, Di Pietro, M., Palumbo M., and Belvedere V. (ORCID:0000-0002-7748-5152)

Abstract

Il testo si propone come manuale utile a studenti e manager per le tematiche relative alla gestione della logistica, delle operations e della supply

Published
2024

2. Gestione in Service dei Flussi Logistici in Ospedale: perché e a quali condizioni?

Author

Belvedere, Valeria, Cervi, L., D’Agnese, G., Damele, A., Palumbo, Michele, Pellegrino, Rossella, Polimeni, J., Russo, A., Villa, Stefano, Belvedere V. (ORCID:0000-0002-7748-5152), Palumbo M., Pellegrino R. (ORCID:0009-0002-9277-4937), Villa S. (ORCID:0000-0001-8111-3098), Belvedere, Valeria, Cervi, L., D’Agnese, G., Damele, A., Palumbo, Michele, Pellegrino, Rossella, Polimeni, J., Russo, A., Villa, Stefano, Belvedere V. (ORCID:0000-0002-7748-5152), Palumbo M., Pellegrino R. (ORCID:0009-0002-9277-4937), and Villa S. (ORCID:0000-0001-8111-3098)

Abstract

Il presente studio, utilizzando differenti metodi d’indagine (survey, interviste semi-strutturate e studio osservazionale), analizza le condizioni organizzative e l'impatto sulla performance del modello di gestione in service dei flussi logistici.

Published
2023

4. Lenalidomide-based triplet regimens in first relapsed multiple myeloma patients: real-world evidence from a propensity score matched analysis

Author

Mangiacavalli, Silvia, primary, Cartia, Claudio Salvatore, additional, Galli, Monica, additional, Pezzatti, Sara, additional, Belotti, Angelo, additional, Fazio, Francesca, additional, Mina, Roberto, additional, Marcatti, Magda, additional, Cafro, Anna, additional, Zambello, Renato, additional, Paris, Laura, additional, Barilà, Gregorio, additional, Olivares, Cecilia, additional, Pompa, Alessandra, additional, Mazza, Rita, additional, Farina, Francesca, additional, Soldarini, Martina, additional, Benvenuti, Pietro, additional, Pagani, Giuseppina, additional, Palumbo, Michele, additional, Masoni, Valeria, additional, Ferretti, Virginia Valeria, additional, Klersy, Catherine, additional, Arcaini, Luca, additional, and Petrucci, Maria Teresa, additional

Published
2022
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5. Cómo el fenómeno de la corrupción afecta a nuestra sociedad: análisis, medición, ideas y teorías

Author

Palumbo, Michele, Hernández Cánovas, Ginés, Mol Gómez-Vázquez, Ana, and Economía, Contabilidad y Finanzas

Subjects
Corruption, Contemporary society, Desarrollo económico y social, Economía Financiera y Contabilidad, Economic and social development, Sociedad contemporánea, Economic sociology, Corrupción, Sociología económica, 5303 Contabilidad Económica
Abstract

A través este trabajo, se intenta describir un fenómeno social que afecta a nuestra sociedad bajo varios puntos de vista, extendiéndose heterogéneamente por todo el mundo. Se va a explicar como el fenómeno de la corrupción se articula en los países del mundo, demostrando que explota sobre todo diferentes situaciones y dinámicas sociales, pero también políticas y económicas para activarse y realizarse. El fenómeno corroe la sociedad en diferentes niveles de la economía tanto macroeconómicos como microeconómicos. En primer lugar, la corrupción es muy difícil de interpretar y evaluar efectivamente y la presencia (o la ausencia) de unos efectos económico-sociales, elecciones políticas e inversiones puedan cambiar considerablemente la posibilidad de desarrollo de este fenómeno. Luego, ha sido útil explicar y medir, a través gráficos oportunos, algunas relaciones entre el IPC de Trasparencia Internacional, es decir el Índice de Percepción de Corrupción o Corruption Percepetion Index en inglés, y varios parámetros macroeconómicos y también si el fenómeno afecte al crecimiento de un País. Los datos analizados sobre el IPC se refieran al año 2018. El apartado final analiza la rara “interpretación benéfica” de como la suministración de sobornos pueda ser leída en un contexto social y empresarial. El trabajo se concluye con la actualización de los últimos datos de Trasparencia Internacional sobre Italia e España y con una rápida consideración de los últimos eventos de actualidad en función de la pandemia de Covid-19 y sus posibles consecuencias. Facultad de Ciencias de la Empresa Universidad Politécnica de Cartagena

Published
2020

6. Impact of the Addition of Daratumumab to the Standard Bortezomib-Thalidomide-Dexamethasone Regimen on Hematopoietic Stem Cell Mobilization and Collection, Post-Transplant Engraftment and Infectious Complications: A Case-Control Multicentre Real-Life Analysis

Author

Cavallaro, Gianluca, Galli, Monica, Paris, Laura, Stefanoni, Paola, Pavoni, Chiara, Mangiacavalli, Silvia, Masoni, Valeria, Palumbo, Michele, Pompa, Alessandra, Cafro, Anna Maria, Pezzatti, Sara, Crippa, Stefano, and Rambaldi, Alessandro

Published
2023
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7. When Does the Cytokine Storm Begin in COVID-19 Patients? A Quick Score to Recognize It

Author

Cappanera, Stefano, primary, Palumbo, Michele, additional, Kwan, Sherman H., additional, Priante, Giulia, additional, Martella, Lucia Assunta, additional, Saraca, Lavinia Maria, additional, Sicari, Francesco, additional, Vernelli, Carlo, additional, Di Giuli, Cinzia, additional, Andreani, Paolo, additional, Mariottini, Alessandro, additional, Francucci, Marsilio, additional, Sensi, Emanuela, additional, Costantini, Monya, additional, Bruzzone, Paolo, additional, D’Andrea, Vito, additional, Gioia, Sara, additional, Cirocchi, Roberto, additional, and Tiri, Beatrice, additional

Published
2021
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8. Prevalence of acquired resistance mutations in a large cohort of perinatally infected HIV-1 patients

Author

Giacometti, Andrea, Butini, Luca, del Gobbo, Romana, Bagnarelli, Patrizia, Tacconi, Danilo, Corbelli, Giovanni, Zanussi, Stefania, Monno, Laura, Punzi, Grazia, Maggiolo, Franco, Calza, Leonardo, Carla Re, Maria, Pristera, Raffaele, Turconi, Paola, Mandas, Antonella, Tini, Sauro, Zoncada, Alessia, Paolini, Elisabetta, Amadio, Giorgio, Sighinolfi, Laura, Corsi, Paola, Galli, Luisa, Di Pietro, Massimo, Colao, Grazia, Tosti, Andrea, Setti, Maurizio, Bruzzone, Bianca, Di Biagio, Antonio, Cenderello, Giovanni, Trezzi, Michele, Orani, Anna, Arcidiacono, Irene, Degiuli, Alberto, De Gennaro, Michele, Chiodera, Alessandro, Scalzini, Alfredo, Palvarini, Loredana, Todaro, Giovanni, Rusconi, Stefano, Gismondo, Maria Rita, Micheli, Valeria, Biondi, Maria Luisa, Capetti, Amedeo, Meraviglia, Paola, Boeri, Enzo, Mussini, Cristina, Pecorari, Monica, Soria, Alessandro, Vecchi, Laura, Santirocchi, Maurizio, Brustia, Diego, Ravanini, Paolo, Dal Bello, Federico, Romano, Nino, Mancuso, Salvatrice, Calzetti, Carlo, Maserati, Renato, Filice, Gaetano, Baldanti, Fausto, Francisci, Daniela, Parruti, Giustino, Polilli, Ennio, Sacchini, Daria, Martinelli, Chiara, Consolini, Rita, Vatteroni, Linda, Vivarelli, Angela, Nerli, Alessandro, Lenzi, Lucia, Magnani, Giacomo, Ortolani, Patrizia, Andreoni, Massimo, Fimiani, Caterina, Palmisano, Lucia, Di Giambenedetto, Simona, Vullo, Vincenzo, Turriziani, Ombretta, Montano, Marco, Antinori, Andrea, Zaccarelli, Mauro, Dentone, Chiara, Gonnelli, Angela, De Luca, Andrea, Palumbo, Michele, Ghisetti, Valeria, Bonora, Stefano, Delle Foglie, Palma, Rossi, Cristina, Mondino, Vincenzo, Malena, Marina, Grossi, Paolo, Seminari, Elena, Poletti, Federica, Ungaro, R., Taramasso, L., Bruzzone, B., Vicenti, I., Galli, L., Borghi, V., Francisci, D., Pecorari, M., Zoncada, A., Callegaro, A.P., Paolini, E., Monno, L., Bonora, S., and Di Biagio, A.

Published
2019
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9. Cómo el fenómeno de la corrupción afecta a nuestra sociedad: análisis, medición, ideas y teorías.

Author

Hernández Cánovas, Ginés, Mol Gómez-Vázquez, Ana, Economía, Contabilidad y Finanzas, Palumbo, Michele, Hernández Cánovas, Ginés, Mol Gómez-Vázquez, Ana, Economía, Contabilidad y Finanzas, and Palumbo, Michele

Abstract

A través este trabajo, se intenta describir un fenómeno social que afecta a nuestra sociedad bajo varios puntos de vista, extendiéndose heterogéneamente por todo el mundo. Se va a explicar como el fenómeno de la corrupción se articula en los países del mundo, demostrando que explota sobre todo diferentes situaciones y dinámicas sociales, pero también políticas y económicas para activarse y realizarse. El fenómeno corroe la sociedad en diferentes niveles de la economía tanto macroeconómicos como microeconómicos. En primer lugar, la corrupción es muy difícil de interpretar y evaluar efectivamente y la presencia (o la ausencia) de unos efectos económico-sociales, elecciones políticas e inversiones puedan cambiar considerablemente la posibilidad de desarrollo de este fenómeno. Luego, ha sido útil explicar y medir, a través gráficos oportunos, algunas relaciones entre el IPC de Trasparencia Internacional, es decir el Índice de Percepción de Corrupción o Corruption Percepetion Index en inglés, y varios parámetros macroeconómicos y también si el fenómeno afecte al crecimiento de un País. Los datos analizados sobre el IPC se refieran al año 2018. El apartado final analiza la rara “interpretación benéfica” de como la suministración de sobornos pueda ser leída en un contexto social y empresarial. El trabajo se concluye con la actualización de los últimos datos de Trasparencia Internacional sobre Italia e España y con una rápida consideración de los últimos eventos de actualidad en función de la pandemia de Covid-19 y sus posibles consecuencias.

Published
2020

10. Prevalence of acquired resistance mutations in a large cohort of perinatally infected HIV-1 patients

Author

Ungaro, R., primary, Taramasso, L., additional, Bruzzone, B., additional, Vicenti, I., additional, Galli, L., additional, Borghi, V., additional, Francisci, D., additional, Pecorari, M., additional, Zoncada, A., additional, Callegaro, A.P., additional, Paolini, E., additional, Monno, L., additional, Bonora, S., additional, Di Biagio, A., additional, Giacometti, Andrea, additional, Butini, Luca, additional, del Gobbo, Romana, additional, Bagnarelli, Patrizia, additional, Tacconi, Danilo, additional, Corbelli, Giovanni, additional, Zanussi, Stefania, additional, Monno, Laura, additional, Punzi, Grazia, additional, Maggiolo, Franco, additional, Calza, Leonardo, additional, Carla Re, Maria, additional, Pristera, Raffaele, additional, Turconi, Paola, additional, Mandas, Antonella, additional, Tini, Sauro, additional, Zoncada, Alessia, additional, Paolini, Elisabetta, additional, Amadio, Giorgio, additional, Sighinolfi, Laura, additional, Corsi, Paola, additional, Galli, Luisa, additional, Di Pietro, Massimo, additional, Colao, Grazia, additional, Tosti, Andrea, additional, Setti, Maurizio, additional, Bruzzone, Bianca, additional, Di Biagio, Antonio, additional, Cenderello, Giovanni, additional, Trezzi, Michele, additional, Orani, Anna, additional, Arcidiacono, Irene, additional, Degiuli, Alberto, additional, De Gennaro, Michele, additional, Chiodera, Alessandro, additional, Scalzini, Alfredo, additional, Palvarini, Loredana, additional, Todaro, Giovanni, additional, Rusconi, Stefano, additional, Gismondo, Maria Rita, additional, Micheli, Valeria, additional, Biondi, Maria Luisa, additional, Capetti, Amedeo, additional, Meraviglia, Paola, additional, Boeri, Enzo, additional, Mussini, Cristina, additional, Pecorari, Monica, additional, Soria, Alessandro, additional, Vecchi, Laura, additional, Santirocchi, Maurizio, additional, Brustia, Diego, additional, Ravanini, Paolo, additional, Dal Bello, Federico, additional, Romano, Nino, additional, Mancuso, Salvatrice, additional, Calzetti, Carlo, additional, Maserati, Renato, additional, Filice, Gaetano, additional, Baldanti, Fausto, additional, Francisci, Daniela, additional, Parruti, Giustino, additional, Polilli, Ennio, additional, Sacchini, Daria, additional, Martinelli, Chiara, additional, Consolini, Rita, additional, Vatteroni, Linda, additional, Vivarelli, Angela, additional, Nerli, Alessandro, additional, Lenzi, Lucia, additional, Magnani, Giacomo, additional, Ortolani, Patrizia, additional, Andreoni, Massimo, additional, Fimiani, Caterina, additional, Palmisano, Lucia, additional, Di Giambenedetto, Simona, additional, Vullo, Vincenzo, additional, Turriziani, Ombretta, additional, Montano, Marco, additional, Antinori, Andrea, additional, Zaccarelli, Mauro, additional, Dentone, Chiara, additional, Gonnelli, Angela, additional, De Luca, Andrea, additional, Palumbo, Michele, additional, Ghisetti, Valeria, additional, Bonora, Stefano, additional, Delle Foglie, Palma, additional, Rossi, Cristina, additional, Mondino, Vincenzo, additional, Malena, Marina, additional, Grossi, Paolo, additional, Seminari, Elena, additional, and Poletti, Federica, additional

Published
2019
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11. Feasibility of a Biomarker-Based Screening for Pre-Symptomatic AL Amyloidosis in Patients With Intermediate/High-Risk MGUS.

Author

Mangiacavalli S, Milani P, Cartia CS, Varettoni M, Palumbo M, Basset M, Masoni V, Nuvolone M, Foli A, Ferretti VV, Merlini G, Arcaini L, and Palladini G

Subjects
Humans, Male, Female, Middle Aged, Aged, Immunoglobulin Light-chain Amyloidosis diagnosis, Immunoglobulin Light-chain Amyloidosis blood, Biomarkers, Monoclonal Gammopathy of Undetermined Significance diagnosis, Monoclonal Gammopathy of Undetermined Significance complications, Monoclonal Gammopathy of Undetermined Significance blood, Feasibility Studies
Abstract

Biomarker-based screening enables early detection of AL amyloidosis in intermediate/high-risk MGUS patients. Our study shows that identifying pre-symptomatic AL through biomarker longitudinal monitoring allows early treatment, leading to significant organ function recovery., (© 2024 The Author(s). American Journal of Hematology published by Wiley Periodicals LLC.)

Published
2025
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12. Lenalidomide-based triplet regimens in first relapsed multiple myeloma patients: real-world evidence from a propensity score matched analysis.

Author

Mangiacavalli S, Cartia CS, Galli M, Pezzatti S, Belotti A, Fazio F, Mina R, Marcatti M, Cafro A, Zambello R, Paris L, Barilà G, Olivares C, Pompa A, Mazza R, Farina F, Soldarini M, Benvenuti P, Pagani G, Palumbo M, Masoni V, Ferretti VV, Klersy C, Arcaini L, and Petrucci MT

Subjects
Humans, Lenalidomide therapeutic use, Propensity Score, Neoplasm Recurrence, Local drug therapy, Dexamethasone therapeutic use, Antineoplastic Combined Chemotherapy Protocols adverse effects, Multiple Myeloma drug therapy
Abstract

Lenalidomide and dexamethasone (Rd)-based triplets, in particular carfilzomib-Rd (KRd) and daratumumab-Rd (DaraRd), represent a standard of care in lenalidomide-sensitive multiple myeloma (MM) patients in first relapse. Meta-analysis of randomized clinical trials (RCT), suggested better outcome with DaraRd. Trying to address this issue in clinical practice, we collected data of 430 consecutive MM patients addressed to Rd-based triplets in first relapse between January 2017 and March 2021. Overall, the most common used regimen was DaraRd, chosen in almost half of the cases (54.4%), followed by KRd (34.6%). Different triplets were used much less commonly. In an attempt to limit the imbalance of a retrospective analysis, we conducted a propensity score matching (PSM) comparison between DaraRd and KRd. After PSM, efficacy of DaraRd versus KRd was similar in terms of overall-response rate (ORR) (OR: 0.9, P=0.685) as well as of very good partial response (VGPR) or better (OR: 0.9, P=0.582). The median progression-free survival (PFS) was significantly longer for DaraRd (29.8 vs. 22.5 months; P=0.028). DaraRd was tolerated better, registering a lower rate of grade 3-4 non-hematological toxicity (OR: 0.4, P<0.001). With the limitations of any retrospective analysis, our real-life PSM comparison between DaraRd and KRd, in first-relapse MM patients, showed better tolerability and prolonged PFS of DaraRd, although with some gaps of performance, in particular of DaraRd, with respect to RCT. Carfilzomib-containing regimens, like KRd, still remain a valid second-line option in the emerging scenario of first-line daratumumab-based therapy.

Published
2023
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