12,166 results on '"Nell, A."'
Search Results
2. Mantis Shrimp: Exploring Photometric Band Utilization in Computer Vision Networks for Photometric Redshift Estimation
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Engel, Andrew, Byler, Nell, Tsou, Adam, Narayan, Gautham, Bonilla, Emmanuel, and Smith, Ian
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Astrophysics - Instrumentation and Methods for Astrophysics ,Computer Science - Artificial Intelligence - Abstract
We present Mantis Shrimp, a multi-survey deep learning model for photometric redshift estimation that fuses ultra-violet (GALEX), optical (PanSTARRS), and infrared (UnWISE) imagery. Machine learning is now an established approach for photometric redshift estimation, with generally acknowledged higher performance in areas with a high density of spectroscopically identified galaxies over template-based methods. Multiple works have shown that image-based convolutional neural networks can outperform tabular-based color/magnitude models. In comparison to tabular models, image models have additional design complexities: it is largely unknown how to fuse inputs from different instruments which have different resolutions or noise properties. The Mantis Shrimp model estimates the conditional density estimate of redshift using cutout images. The density estimates are well calibrated and the point estimates perform well in the distribution of available spectroscopically confirmed galaxies with (bias = 1e-2), scatter (NMAD = 2.44e-2) and catastrophic outlier rate ($\eta$=17.53$\%$). We find that early fusion approaches (e.g., resampling and stacking images from different instruments) match the performance of late fusion approaches (e.g., concatenating latent space representations), so that the design choice ultimately is left to the user. Finally, we study how the models learn to use information across bands, finding evidence that our models successfully incorporates information from all surveys. The applicability of our model to the analysis of large populations of galaxies is limited by the speed of downloading cutouts from external servers; however, our model could be useful in smaller studies such as generating priors over redshift for stellar population synthesis.
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- 2025
3. Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancer.
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Link, Jason, Eng, Jennifer, Pelz, Carl, MacPherson-Hawthorne, Kevin, Worth, Patrick, Sivagnanam, Shamaline, Keith, Dove, Owen, Sydney, Langer, Ellen, Grossblatt-Wait, Alison, Salgado-Garza, Gustavo, Creason, Allison, Protzek, Sara, Egger, Julian, Holly, Hannah, Heskett, Michael, Chin, Koei, Kirchberger, Nell, Betre, Konjit, Bucher, Elmar, Kilburn, David, Hu, Zhi, Munks, Michael, English, Isabel, Tsuda, Motoyuki, Goecks, Jeremy, Demir, Emek, Adey, Andrew, Kardosh, Adel, Lopez, Charles, Sheppard, Brett, Guimaraes, Alex, Brinkerhoff, Brian, Morgan, Terry, Mills, Gordon, Coussens, Lisa, Brody, Jonathan, and Sears, Rosalie
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Humans ,Lung Neoplasms ,Pancreatic Neoplasms ,Liver Neoplasms ,T-Lymphocytes ,Neoplasm Recurrence ,Local ,Carcinoma ,Pancreatic Ductal ,Male ,Female ,Prognosis - Abstract
Patients with metastatic pancreatic ductal adenocarcinoma survive longer if disease spreads to the lung but not the liver. Here we generated overlapping, multi-omic datasets to identify molecular and cellular features that distinguish patients whose disease develops liver metastasis (liver cohort) from those whose disease develops lung metastasis without liver metastases (lung cohort). Lung cohort patients survived longer than liver cohort patients, despite sharing the same tumor subtype. We developed a primary organotropism (pORG) gene set enriched in liver cohort versus lung cohort primary tumors. We identified ongoing replication stress response pathways in high pORG/liver cohort tumors, whereas low pORG/lung cohort tumors had greater densities of lymphocytes and shared T cell clonal responses. Our study demonstrates that liver-avid pancreatic ductal adenocarcinoma is associated with tolerance to ongoing replication stress, limited tumor immunity and less-favorable outcomes, whereas low replication stress, lung-avid/liver-averse tumors are associated with active tumor immunity that may account for favorable outcomes.
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- 2025
4. Effect of dynamical electron correlations on the tunnelling magnetoresistance of Fe/MgO/Fe(001) junctions
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Nell, Declan, Sanvito, Stefano, Rungger, Ivan, and Droghetti, Andrea
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Condensed Matter - Strongly Correlated Electrons ,Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Materials Science - Abstract
We employ dynamical mean-field theory (DMFT) combined with density functional theory (DFT) and the non-equilibrium Green's function technique to investigate the steady-state transport properties of an Fe/MgO/Fe magnetic tunnel junction (MTJ), focusing on the impact of dynamical electron correlations on the Fe $3d$ orbitals. By applying the rigid shift approximation, we extend the calculations from zero- to finite-bias in a simple and computationally efficient manner, obtaining the bias-dependent electronic structure and current-versus-voltage characteristic curve in both the parallel and antiparallel configurations. In particular, we find that dynamical electron correlation manifests as a reduction in the spin splitting of the Fe $3d_{z^2}$ state compared to DFT predictions and introduces a finite relaxation time. The impact of these effects on the transport properties, however, varies significantly between magnetic configurations. In the parallel configuration, the characteristic curves obtained with DFT and DMFT are similar, as the transport is mostly due to the coherent transmission of spin-up electrons through the MgO barrier. Conversely, in the antiparallel configuration, correlation effects become more significant, with DMFT predicting a sharp current increase due to bias-driven inelastic electron-electron scattering. As a consequence, DMFT gives a lower bias threshold for the suppression of the tunneling magnetoresistance ratio compared to DFT, matching experimental data more closely.
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- 2024
5. The assembly, characterization, and performance of SISTINE
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Nell, Nicholas, France, Kevin, Kruczek, Nicholas, Fleming, Brian, Ulrich, Stefan, Behr, Patrick, Quijada, Manuel A., Del Hoyo, Javier, and Hennessy, John
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Earth and Planetary Astrophysics - Abstract
The Suborbital Imaging Spectrograph for Transition region Irradiance from Nearby Exoplanet host stars (SISTINE) is a rocket-borne ultraviolet (UV) imaging spectrograph designed to probe the radiation environment of nearby stars. SISTINE operates over a bandpass of 98 -- 127 and 130 -- 158 nm, capturing a broad suite of emission lines tracing the full 10$^4$ -- 10$^5$ K formation temperature range critical for reconstructing the full UV radiation field incident on planets orbiting solar-type stars. SISTINE serves as a platform for key technology developments for future ultraviolet observatories. SISTINE operates at moderate resolving power ($R\sim$1500) while providing spectral imaging over an angular extent of $\sim$6', with $\sim$2" resolution at the slit center. The instrument is composed of an f/14 Cassegrain telescope that feeds a 2.1x magnifying spectrograph, utilizing a blazed holographically ruled diffraction grating and a powered fold mirror. Spectra are captured on a large format microchannel plate (MCP) detector consisting of two 113 x 42 mm segments each read out by a cross delay-line anode. Several novel technologies are employed in SISTINE to advance their technical maturity in support of future NASA UV/optical astronomy missions. These include enhanced aluminum lithium fluoride coatings (eLiF), atomic layer deposition (ALD) protective optical coatings, and ALD processed large format MCPs. SISTINE was launched a total of three times with two of the three launches successfully observing targets Procyon A and $\alpha$ Centauri A and B.
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- 2024
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6. A compatible finite element discretisation for moist shallow water equations
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Hartney, Nell, Bendall, Thomas M., and Shipton, Jemma
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Mathematics - Numerical Analysis ,Physics - Fluid Dynamics - Abstract
The moist shallow water equations offer a promising route for advancing understanding of the coupling of physical parametrisations and dynamics in numerical atmospheric models, an issue known as 'physics-dynamics coupling'. Without moist physics, the traditional shallow water equations are a simplified form of the atmospheric equations of motion and so are computationally cheap, but retain many relevant dynamical features of the atmosphere. Introducing physics into the shallow water model in the form of moisture provides a tool to experiment with numerical techniques for physics-dynamics coupling in a simple dynamical model. In this paper, we compare some of the different moist shallow water models by writing them in a general formulation. The general formulation encompasses three existing forms of the moist shallow water equations and also a fourth, previously unexplored formulation. The equations are coupled to a three-state moist physics scheme that interacts with the resolved flow through source terms and produces two-way physics-dynamics feedback. We present a new compatible finite element discretisation of the equations and apply it to the different formulations of the moist shallow water equations in three test cases. The results show that the models capture generation of cloud and rain and physics-dynamics interactions, and demonstrate some differences between moist shallow water formulations and the implications of these different modelling choices.
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- 2024
7. Long-Range Biometric Identification in Real World Scenarios: A Comprehensive Evaluation Framework Based on Missions
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Aykac, Deniz, Brogan, Joel, Barber, Nell, Shivers, Ryan, Zhang, Bob, Sacca, Dallas, Tipton, Ryan, Jager, Gavin, Garret, Austin, Love, Matthew, Goddard, Jim, Cornett III, David, and Bolme, David S.
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Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
The considerable body of data available for evaluating biometric recognition systems in Research and Development (R\&D) environments has contributed to the increasingly common problem of target performance mismatch. Biometric algorithms are frequently tested against data that may not reflect the real world applications they target. From a Testing and Evaluation (T\&E) standpoint, this domain mismatch causes difficulty assessing when improvements in State-of-the-Art (SOTA) research actually translate to improved applied outcomes. This problem can be addressed with thoughtful preparation of data and experimental methods to reflect specific use-cases and scenarios. To that end, this paper evaluates research solutions for identifying individuals at ranges and altitudes, which could support various application areas such as counterterrorism, protection of critical infrastructure facilities, military force protection, and border security. We address challenges including image quality issues and reliance on face recognition as the sole biometric modality. By fusing face and body features, we propose developing robust biometric systems for effective long-range identification from both the ground and steep pitch angles. Preliminary results show promising progress in whole-body recognition. This paper presents these early findings and discusses potential future directions for advancing long-range biometric identification systems based on mission-driven metrics.
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- 2024
8. From Data to Insights: A Covariate Analysis of the IARPA BRIAR Dataset for Multimodal Biometric Recognition Algorithms at Altitude and Range
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Bolme, David S., Aykac, Deniz, Shivers, Ryan, Brogan, Joel, Barber, Nell, Zhang, Bob, Davies, Laura, and Cornett III, David
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Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
This paper examines covariate effects on fused whole body biometrics performance in the IARPA BRIAR dataset, specifically focusing on UAV platforms, elevated positions, and distances up to 1000 meters. The dataset includes outdoor videos compared with indoor images and controlled gait recordings. Normalized raw fusion scores relate directly to predicted false accept rates (FAR), offering an intuitive means for interpreting model results. A linear model is developed to predict biometric algorithm scores, analyzing their performance to identify the most influential covariates on accuracy at altitude and range. Weather factors like temperature, wind speed, solar loading, and turbulence are also investigated in this analysis. The study found that resolution and camera distance best predicted accuracy and findings can guide future research and development efforts in long-range/elevated/UAV biometrics and support the creation of more reliable and robust systems for national security and other critical domains.
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- 2024
9. Colorado Ultraviolet Transit Experiment Near-Ultraviolet Transmission Spectroscopy of the Ultra-hot Jupiter KELT-9b
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Egan, Arika, France, Kevin, Sreejith, Aickara Gopinathan, Fossati, Luca, Koskinen, Tommi, Fleming, Brian, Nell, Nicholas, Suresh, Ambily, Cauley, P. Wilson, Desert, Jean-Michele, Petit, Pascal, and Vidotto, Aline A.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
We present new near-ultraviolet (NUV, $\lambda$ = 2479 $-$ 3306 $\r{A}$) transmission spectroscopy of KELT-9b, the hottest known exoplanet, obtained with the Colorado Ultraviolet Transit Experiment ($CUTE$) CubeSat. Two transits were observed on September 28th and September 29th 2022, referred to as Visits 1 and 2 respectively. Using a combined transit and systematics model for each visit, the best-fit broadband NUV light curves are R$_{\text{p}}$/R$_{\star}$ $=$ 0.136$_{0.0146}^{0.0125}$ for Visit 1 and R$_{\text{p}}$/R$_{\star}$ $=$ 0.111$_{0.0190}^{0.0162}$ for Visit 2, appearing an average of 1.54$\times$ larger in the NUV than at optical wavelengths. While the systematics between the two visits vary considerably, the two broadband NUV light curves are consistent with each other. A transmission spectrum with 25 $\r{A}$ bins suggests a general trend of excess absorption in the NUV, consistent with expectations for ultra-hot Jupiters. Although we see an extended atmosphere in the NUV, the reduced data lack the sensitivity to probe individual spectral lines.
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- 2024
10. The Solar eruptioN Integral Field Spectrograph
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Herde, Vicki L., Chamberlin, Phillip C., Schmit, Don, Daw, Adrian, Milligan, Ryan O., Polito, Vanessa, Bose, Souvik, Boyajian, Spencer, Buedel, Paris, Edgar, Will, Gebben, Alex, Gong, Qian, Jacobsen, Ross, Nell, Nicholas, Schwab, Bennet, Sims, Alan, Summers, David, Turner, Zachary, Valade, Trace, and Wallace, Joseph
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Instrumentation and Methods for Astrophysics ,Physics - Instrumentation and Detectors ,Physics - Space Physics - Abstract
The Solar eruptioN Integral Field Spectrograph (SNIFS) is a solar-gazing spectrograph scheduled to fly in the summer of 2025 on a NASA sounding rocket. Its goal is to view the solar chromosphere and transition region at a high cadence (1s) both spatially (0.5") and spectrally (33 m{\AA}) viewing wavelengths around Lyman Alpha (1216 {\AA}), Si iii (1206 {\AA}) and O v (1218 {\AA}) to observe spicules, nanoflares, and possibly a solar flare. This time cadence will provide yet-unobserved detail about fast-changing features of the Sun. The instrument is comprised of a Gregorian-style reflecting telescope combined with a spectrograph via a specialized mirrorlet array that focuses the light from each spatial location in the image so that it may be spectrally dispersed without overlap from neighboring locations. This paper discusses the driving science, detailed instrument and subsystem design, and pre-integration testing of the SNIFS instrument., Comment: 22 pages (not including references), 7 figures, submitting to Solar Physics
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- 2024
11. PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections
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Shepard, Ryan M, Ghebremedhin, Anghesom, Pratumchai, Isaraphorn, Robinson, Sally R, Betts, Courtney, Hu, Jingjing, Sasik, Roman, Fisch, Kathleen M, Zak, Jaroslav, Chen, Hui, Paradise, Marc, Rivera, Jason, Amjad, Mohammad, Uchiyama, Satoshi, Seo, Hideya, Campos, Alejandro D, Dayao, Denise Ann, Tzipori, Saul, Piedra-Mora, Cesar, Das, Soumita, Hasteh, Farnaz, Russo, Hana, Sun, Xin, Xu, Le, Crotty Alexander, Laura E, Duran, Jason M, Odish, Mazen, Pretorius, Victor, Kirchberger, Nell C, Chin, Shao-Ming, Von Schalscha, Tami, Cheresh, David, Morrey, John D, Alargova, Rossitza, O'Connell, Brenda, Martinot, Theodore A, Patel, Sandip P, Nizet, Victor, Martinot, Amanda J, Coussens, Lisa M, Teijaro, John R, and Varner, Judith A
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Biomedical and Clinical Sciences ,Clinical Sciences ,Infectious Diseases ,Lung ,Biodefense ,Coronaviruses ,Emerging Infectious Diseases ,2.1 Biological and endogenous factors ,Infection ,Good Health and Well Being ,Animals ,Humans ,Mice ,Capillary Permeability ,Class Ib Phosphatidylinositol 3-Kinase ,COVID-19 ,COVID-19 Drug Treatment ,Cytokine Release Syndrome ,Inflammation ,Methicillin-Resistant Staphylococcus aureus ,Mice ,Inbred C57BL ,Phosphoinositide-3 Kinase Inhibitors ,SARS-CoV-2 ,Staphylococcal Infections ,Biological Sciences ,Medical and Health Sciences ,Medical biotechnology ,Biomedical engineering - Abstract
Virulent infectious agents such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and methicillin-resistant Staphylococcus aureus (MRSA) induce tissue damage that recruits neutrophils, monocyte, and macrophages, leading to T cell exhaustion, fibrosis, vascular leak, epithelial cell depletion, and fatal organ damage. Neutrophils, monocytes, and macrophages recruited to pathogen-infected lungs, including SARS-CoV-2-infected lungs, express phosphatidylinositol 3-kinase gamma (PI3Kγ), a signaling protein that coordinates both granulocyte and monocyte trafficking to diseased tissues and immune-suppressive, profibrotic transcription in myeloid cells. PI3Kγ deletion and inhibition with the clinical PI3Kγ inhibitor eganelisib promoted survival in models of infectious diseases, including SARS-CoV-2 and MRSA, by suppressing inflammation, vascular leak, organ damage, and cytokine storm. These results demonstrate essential roles for PI3Kγ in inflammatory lung disease and support the potential use of PI3Kγ inhibitors to suppress inflammation in severe infectious diseases.
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- 2024
12. Half-metallic transport and spin-polarized tunneling through the van der Waals ferromagnet Fe${_4}$GeTe$_{2}$
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Halder, Anita, Nell, Declan, Sihi, Antik, Bajaj, Akash, Sanvito, Stefano, and Droghetti, Andrea
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Condensed Matter - Materials Science - Abstract
The recent emergence of van der Waals (vdW) ferromagnets has opened new opportunities for designing spintronic devices. We theoretically investigate the coherent spin-dependent transport properties of the vdW ferromagnet Fe$_4$GeTe$_2$, by using density functional theory combined with the non-equilibrium Green's functions method. We find that the conductance in the direction perpendicular to the layers is half-metallic, namely it is entirely spin-polarized, as a result of the material's electronic structure. This characteristic persists from bulk to single layer, even under significant bias voltages, and it is little affected by spin-orbit coupling and electron correlation. Motivated by this observation, we then investigate the tunnel magnetoresistance (TMR) effect in an magnetic tunnel junction, which comprises two Fe$_4$GeTe$_2$ layers separated by the vdW gap acting as insulating barrier. We predict a TMR ratio of almost 500\%, which can be further boosted by increasing the number of Fe$_4$GeTe$_2$ layers in the junction., Comment: 16 pages, 15 figures and 4 tables
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- 2024
13. Preliminary Report on Mantis Shrimp: a Multi-Survey Computer Vision Photometric Redshift Model
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Engel, Andrew, Narayan, Gautham, and Byler, Nell
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Astrophysics - Instrumentation and Methods for Astrophysics ,Computer Science - Artificial Intelligence - Abstract
The availability of large, public, multi-modal astronomical datasets presents an opportunity to execute novel research that straddles the line between science of AI and science of astronomy. Photometric redshift estimation is a well-established subfield of astronomy. Prior works show that computer vision models typically outperform catalog-based models, but these models face additional complexities when incorporating images from more than one instrument or sensor. In this report, we detail our progress creating Mantis Shrimp, a multi-survey computer vision model for photometric redshift estimation that fuses ultra-violet (GALEX), optical (PanSTARRS), and infrared (UnWISE) imagery. We use deep learning interpretability diagnostics to measure how the model leverages information from the different inputs. We reason about the behavior of the CNNs from the interpretability metrics, specifically framing the result in terms of physically-grounded knowledge of galaxy properties., Comment: 4 pages, 1 figure, 1 table. Submitted to AI4Differential Equations in Science Workshop at ICLR24. Public repository unavailable while under institutional review
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- 2024
14. FLUID: A rocket-borne pathfinder instrument for high efficiency UV band selection imaging
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Nell, Nicholas, Kruczek, Nicholas, France, Kevin, Ulrich, Stefan, Behr, Patrick, and Farr, Emily
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The Far- and Lyman-Ultraviolet Imaging Demonstrator (FLUID) is a rocket-borne arcsecond-level ultraviolet (UV) imaging instrument covering four bands between 92 -- 193 nm. FLUID will observe nearby galaxies to find and characterize the most massive stars that are the primary drivers of the chemical and dynamical evolution of galaxies, and the co-evolution of the surrounding galactic environment. The FLUID short wave channel is designed to suppress efficiency at Lyman-$\alpha$ (121.6 nm), while enhancing the reflectivity of shorter wavelengths. Utilizing this technology, FLUID will take the first ever images of local galaxies isolated in the Lyman ultraviolet (90 -- 120 nm). As a pathfinder instrument, FLUID will employ and increase the TRL of band-selecting UV coatings, and solar-blind UV detector technologies including microchannel plate and solid state detectors; technologies prioritized in the 2022 NASA Astrophysical Biennial Technology Report. These technologies enable high throughput and high sensitivity observations in the four co-aligned UV imaging bands that make up the FLUID instrument. We present the design of FLUID, status on the technology development, and results from initial assembly and calibration of the FLUID instrument., Comment: Accepted to JATIS, March 18, 2024
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- 2024
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15. Preserved bevacizumab (Avastin®) eye drops for application in multidose containers – an in-vitro characterisation
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Ulrike Lessiak, Tania Brandstoetter, Barbara Nell, Klara Klein, Georg Mlynek, Lukas Wimmer, Lisa Scheiblecker, Alexander Tichy, and Andrea Hoelbl-Kovacic
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Anti-VEGF ,Protein aggregation ,Cornea ,Angiogenesis ,Veterinary medicine ,SF600-1100 - Abstract
Abstract Purpose Monoclonal antibodies have made an immense contribution to the treatment of various human diseases. We aimed at investigating an affordable treatment option for veterinary patients with corneal neovascularization by adding the preservative benzalkonium chloride (BAC) to bevacizumab (Avastin®) for usage in multidose containers. A comprehensive analytical similarity assessment of preserved and unpreserved bevacizumab after dilution and storage was carried out. Methods Diluted and preserved bevacizumab was analysed at different time points for a 4-week period and compared with unpreserved bevacizumab at the same concentrations at each time point. Native-PAGE, immunoblotting and HP-SEC were used to observe aggregation and degradation. DLS provided information about particle size and dispersity. Bevacizumab quantified by ELISA was conducted to determine its biological activity. Dose response curves and cell migration assays were performed to detect possible toxic effects and determine biological activity and efficacy of the drug using HUVECs. Results Native-PAGE, immunoblotting and HP-SEC analysis did not show any changes or degradation products in the presence of BAC and after storage compared to unpreserved bevacizumab. The overlapping intensity-based particle size distribution obtained from DLS showed similarity in all tested groups and homogeneity was maintained. ELISA accurately detected bevacizumab at different concentrations. HUVECs incubated with preserved or unpreserved bevacizumab showed a comparable effect on cell migration. No decrease in cell viability was detected. Conclusion Equivalence tests demonstrated that bevacizumab is stable after dilution, storage and preservation with BAC. Our study shows that preserved bevacizumab applied in mutidose containers can be considered as a cost-effective alternative to the otherwise single-dose treatments.
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- 2025
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16. Systems immunology integrates the complex endotypes of recessive dystrophic epidermolysis bullosa
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Nell Hirt, Enzo Manchon, Qian Chen, Clara Delaroque, Aurelien Corneau, Patrice Hemon, Safaa Saker-Delye, Pauline Bataille, Jean-David Bouaziz, Emmanuelle Bourrat, Alain Hovnanian, Helene Le Buanec, Fawzi Aoudjit, Hicham El Costa, Nabila Jabrane-Ferrat, and Reem Al-Daccak
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Science - Abstract
Abstract Endotypes are characterized by the immunological, inflammatory, metabolic, and remodelling pathways that explain the mechanisms underlying the clinical presentation (phenotype) of a disease. Recessive dystrophic epidermolysis bullosa (RDEB) is a severe blistering disease caused by COL7A1 pathogenic variants. Although underscored by animal studies, the endotypes of human RDEB are poorly understood. To fill this gap, we apply systems immunology approaches using single-cell high-dimensional techniques to capture the signature of peripheral immune cells and the diversity of metabolic profiles in RDEB adults, sampled outside of any opportunistic infection and active cancer. Our study, demonstrates the particular inflammation and immunity characteristics of RDEB adults, with activated / effector T and dysfunctional natural killer cell signatures, concomitant with an overall pro-inflammatory lipid signature. Artificial intelligence prediction models and principal component analysis stress that RDEB is not solely confined to cutaneous issues but has complex systemic endotypes marked by immune dysregulation and hyperinflammation. By characterising the phenotype-endotype association in RDEB adults, our study lays the groundwork for translational interventions that could by lessening inflammation, alleviate the everlasting suffering of RDEB patients, while awaiting curative genetic therapies.
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- 2025
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17. A Cascaded Neural Network System For Rating Student Performance In Surgical Knot Tying Simulation
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Xue, Yunzhe, Eletta, Olanrewaju, Ady, Justin W., Patel, Nell M., Bongu, Advaith, and Roshan, Usman
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Computer Science - Computer Vision and Pattern Recognition ,Electrical Engineering and Systems Science - Image and Video Processing - Abstract
As part of their training all medical students and residents have to pass basic surgical tasks such as knot tying, needle-passing, and suturing. Their assessment is typically performed in the operating room by surgical faculty where mistakes and failure by the student increases the operation time and cost. This evaluation is quantitative and has a low margin of error. Simulation has emerged as a cost effective option but it lacks assessment or requires additional expensive hardware for evaluation. Apps that provide training videos on surgical knot trying are available to students but none have evaluation. We propose a cascaded neural network architecture that evaluates a student's performance just from a video of themselves simulating a surgical knot tying task. Our model converts video frame images into feature vectors with a pre-trained deep convolutional network and then models the sequence of frames with a temporal network. We obtained videos of medical students and residents from the Robert Wood Johnson Hospital performing knot tying on a standardized simulation kit. We manually annotated each video and proceeded to do a five-fold cross-validation study on them. Our model achieves a median precision, recall, and F1-score of 0.71, 0.66, and 0.65 respectively in determining the level of knot related tasks of tying and pushing the knot. Our mean precision score averaged across different probability thresholds is 0.8. Both our F1-score and mean precision score are 8% and 30% higher than that of a recently published study for the same problem. We expect the accuracy of our model to further increase as we add more training videos to the model thus making it a practical solution that students can use to evaluate themselves., Comment: To appear in proceedings of 11th IEEE International Conference on Healthcare Informatics (ICHI) 2023
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- 2023
18. Language use predicts symptoms of fragile X-associated tremor/ataxia syndrome in men and women with the FMR1 premutation
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Maltman, Nell, Sterling, Audra, Santos, Ellery, and Hagerman, Randi
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Biological Psychology ,Cognitive and Computational Psychology ,Psychology ,Clinical Research ,Neurodegenerative ,Women's Health ,Fragile X Syndrome ,Rare Diseases ,Neurosciences ,Intellectual and Developmental Disabilities (IDD) ,Brain Disorders ,Humans ,Male ,Fragile X Mental Retardation Protein ,Female ,Tremor ,Aged ,Middle Aged ,Ataxia ,Aged ,80 and over ,Language ,Cross-Sectional Studies ,Cognition ,FMR1 ,Fragile X-associated tremor/ataxia syndrome ,Executive function - Abstract
Fragile X-associated tremor/ataxia syndrome (FXTAS) is an age-related neurodegenerative disorder caused by a premutation of the FMR1 gene on the X chromosome. Despite the pervasive physical and cognitive effects of FXTAS, no studies have examined language in symptomatic males and females, limiting utility as an outcome measure in clinical trials of FXTAS. The goal of this work is to determine (a) the extent to which male and female FMR1 premutation carriers with FXTAS symptoms differ in their language use and (b) whether language production predicts FXTAS symptoms. Thirty-one individuals with the FMR1 premutation (21M, 10F), ages 58-85 years with some symptoms of FXTAS, were recruited from a larger cross-sectional study. Participants completed a five-minute monologic language sample. Language transcripts were assessed for rate of dysfluencies, lexical-semantics, syntax, and speech rate. Multivariable linear and ordinal regressions were used to predict FXTAS-associated symptoms, cognitive functioning, and executive functioning. Males and females did not differ in their language use. Language production predicted FXTAS symptom severity, cognitive functioning, and executive functioning. Language production difficulties may co-occur with FXTAS-associated symptoms and may be a viable outcome measure in future clinical trials, with future research needed.
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- 2024
19. Five Guiding Principles for Effective Voluntary Agreements: A Case Study on VAs for Water and Habitat in California’s Bay-Delta Watershed
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Marcus, Felicia, Green Nylen, Nell, Owen, Dave, and Kiparsky, Michael
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Bay-Delta ,Bay-Delta watershed ,instream flow ,voluntary agreements ,Water Quality Control Plan - Abstract
California has increasingly emphasized efforts to develop voluntary agreements (VAs) with water users as a means of achieving regulatory goals in certain watersheds. In theory, a VA can combine the protectiveness of a regulatory backstop with the creativity and flexibility of a negotiated deal to produce outcomes as good as, or better than, those achievable through strict application of regulatory requirements alone. However, reality has not always measured up to this ideal. This policy paper uses the Bay-Delta watershed as a case study to inform five principles to guide the appropriate use and evaluation of VAs.
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- 2024
20. The Past, Present, and Future of the Brain Imaging Data Structure (BIDS)
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Poldrack, Russell A., Markiewicz, Christopher J., Appelhoff, Stefan, Ashar, Yoni K., Auer, Tibor, Baillet, Sylvain, Bansal, Shashank, Beltrachini, Leandro, Benar, Christian G., Bertazzoli, Giacomo, Bhogawar, Suyash, Blair, Ross W., Bortoletto, Marta, Boudreau, Mathieu, Brooks, Teon L., Calhoun, Vince D., Castelli, Filippo Maria, Clement, Patricia, Cohen, Alexander L, Cohen-Adad, Julien, D'Ambrosio, Sasha, de Hollander, Gilles, de la iglesia-Vayá, María, de la Vega, Alejandro, Delorme, Arnaud, Devinsky, Orrin, Draschkow, Dejan, Duff, Eugene Paul, DuPre, Elizabeth, Earl, Eric, Esteban, Oscar, Feingold, Franklin W., Flandin, Guillaume, galassi, anthony, Gallitto, Giuseppe, Ganz, Melanie, Gau, Rémi, Gholam, James, Ghosh, Satrajit S., Giacomel, Alessio, Gillman, Ashley G, Gleeson, Padraig, Gramfort, Alexandre, Guay, Samuel, Guidali, Giacomo, Halchenko, Yaroslav O., Handwerker, Daniel A., Hardcastle, Nell, Herholz, Peer, Hermes, Dora, Honey, Christopher J., Innis, Robert B., Ioanas, Horea-Ioan, Jahn, Andrew, Karakuzu, Agah, Keator, David B., Kiar, Gregory, Kincses, Balint, Laird, Angela R., Lau, Jonathan C., Lazari, Alberto, Legarreta, Jon Haitz, Li, Adam, Li, Xiangrui, Love, Bradley C., Lu, Hanzhang, Maumet, Camille, Mazzamuto, Giacomo, Meisler, Steven L., Mikkelsen, Mark, Mutsaerts, Henk, Nichols, Thomas E., Nikolaidis, Aki, Nilsonne, Gustav, Niso, Guiomar, Norgaard, Martin, Okell, Thomas W, Oostenveld, Robert, Ort, Eduard, Park, Patrick J., Pawlik, Mateusz, Pernet, Cyril R., Pestilli, Franco, Petr, Jan, Phillips, Christophe, Poline, Jean-Baptiste, Pollonini, Luca, Raamana, Pradeep Reddy, Ritter, Petra, Rizzo, Gaia, Robbins, Kay A., Rockhill, Alexander P., Rogers, Christine, Rokem, Ariel, Rorden, Chris, Routier, Alexandre, Saborit-Torres, Jose Manuel, Salo, Taylor, Schirner, Michael, Smith, Robert E., Spisak, Tamas, Sprenger, Julia, Swann, Nicole C., Szinte, Martin, Takerkart, Sylvain, Thirion, Bertrand, Thomas, Adam G., Torabian, Sajjad, Varoquaux, Gael, Voytek, Bradley, Welzel, Julius, Wilson, Martin, Yarkoni, Tal, and Gorgolewski, Krzysztof J.
- Subjects
Quantitative Biology - Other Quantitative Biology - Abstract
The Brain Imaging Data Structure (BIDS) is a community-driven standard for the organization of data and metadata from a growing range of neuroscience modalities. This paper is meant as a history of how the standard has developed and grown over time. We outline the principles behind the project, the mechanisms by which it has been extended, and some of the challenges being addressed as it evolves. We also discuss the lessons learned through the project, with the aim of enabling researchers in other domains to learn from the success of BIDS.
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- 2023
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21. Clark measures on polydiscs associated to product functions and multiplicative embeddings
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Jacobsson, Nell
- Subjects
Mathematics - Complex Variables ,28A25, 28A35, 32A10, 30J05 - Abstract
We study Clark measures on the unit polydisc, giving an overview of recent research and investigating the Clark measures of some new examples of multivariate inner functions. In particular, we study the relationship between Clark measures and multiplication; first by introducing compositions of inner functions and multiplicative embeddings, and then by studying products of one-variable inner functions., Comment: 21 pages, 5 figures
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- 2023
22. CUTE reveals escaping metals in the upper atmosphere of the ultra-hot Jupiter WASP-189b
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Sreejith, A. G., France, Kevin, Fossati, Luca, Koskinen, Tommi T., Egan, Arika, Cauley, P. Wilson, Cubillos, Patricio. E., Ambily, S., Huang, Chenliang, Lavvas, 5 Panayotis, Fleming, Brian T., Desert, Jean-Michel, Nell, Nicholas, Petit, Pascal, and Vidotto, Aline
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
Ultraviolet observations of Ultra-hot Jupiters (UHJs), exoplanets with temperatures over 2000\,K, provide us with an opportunity to investigate if and how atmospheric escape shapes their upper atmosphere. Near-ultraviolet transit spectroscopy offers a unique tool to study this process owing to the presence of strong metal lines and a bright photospheric continuum as the light source against which the absorbing gas is observed. WASP-189b is one of the hottest planets discovered to date, with a day-side temperature of about 3400\,K orbiting a bright A-type star. We present the first near-ultraviolet observations of WASP-189b, acquired with the Colorado Ultraviolet Transit Experiment ($CUTE$). $CUTE$ is a 6U NASA-funded ultraviolet spectroscopy mission, dedicated to monitoring short-period transiting planets. WASP-189b was one of the $CUTE$ early science targets and was observed during three consecutive transits in March 2022. We present an analysis of the $CUTE$ observations and results demonstrating near-ultraviolet (2500--3300~\AA) broadband transit depth ($1.08^{+0.08}_{-0.08}\%$) of about twice the visual transit depth indicating that the planet has an extended, hot upper atmosphere with a temperature of about 15000\,K and a moderate mass loss rate of about \SI{4e8}{\kg\per\second}. We observe absorption by Mg{\sc ii} lines ($R_p/R_s$ of $0.212^{+0.038}_{-0.061}$) beyond the Roche lobe at $>$4$\sigma$ significance in the transmission spectrum at a resolution of 10~\AA, while at lower resolution (100~\AA), we observe a quasi-continuous absorption signal consistent with a "forest" of low-ionization metal absorption dominated by Fe{\sc ii}. The results suggest an upper atmospheric temperature ($\sim15000$\,K), higher than that predicted by current state-of-the-art hydrodynamic models., Comment: Accepted for publication in The Astrophysical Journal Letters
- Published
- 2023
23. The Radiation Environments of Middle-Aged F-Type Stars
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Aguirre, F. Cruz, France, K., Nell, N., Kruczek, N., Fleming, B., Hinton, P. C., Ulrich, S., and Behr, P. R.
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Far ultraviolet (FUV) emission lines from dwarf stars are important driving sources of photochemistry in planetary atmospheres. Properly interpreting spectral features of planetary atmospheres critically depends on the emission of its host star. While the spectral energy distributions (SEDs) of K- and M-type stars have been extensively characterized by previous observational programs, the full X-ray to infrared SED of F-type stars has not been assembled to support atmospheric modeling. On the second flight of the Suborbital Imaging Spectrograph for Transition-region Irradiance from Nearby Exoplanet host stars (SISTINE-2) rocket-borne spectrograph, we successfully captured the FUV spectrum of Procyon A (F5 IV-V) and made the first simultaneous observation of several emission features across the FUV bandpass (1010 - 1270 and 1300 - 1565 \r{A}) of any cool star. We combine flight data with stellar models and archival observations to develop the first SED of a mid-F star. We model the response of a modern Earth-like exoplanet's upper atmosphere to the heightened X-ray and extreme ultraviolet radiation within the habitable zone of Procyon A. These models indicate that this planet would not experience significant atmospheric escape. We simulate observations of the Ly$\alpha$ transit signal of this exoplanet with the Hubble Space Telescope (HST) and the Habitable Worlds Observatory (HWO). While marginally detectable with HST, we find that H I Ly$\alpha$ transits of potentially habitable exoplanets orbiting high radial velocity F-type stars could be observed with HWO for targets up to 150 pc away., Comment: 22 Pages, 13 Figures, 3 Tables, to be published in ApJ
- Published
- 2023
24. The Uncontrollability of Preaching: Some Elements of Mystery in the Christmas Sermons of Thabo Makgoba
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Ian Nell
- Subjects
preaching ,mystery ,uncontrollability ,thabo makgoba ,christmas sermons ,hartmut rosa ,john de gruchy ,Practical Theology ,BV1-5099 - Abstract
When you preach, you know from experience that what happens in the preaching event is uncontrollable and, therefore, full of mystery. The liturgy and the sermon are part of it and are related to something that happens, but we know this ‘something’ is uncontrollable. Investigation and reflection on resonance in preaching are on the trail of the mystery of the sermon as an event. We know that something mysterious happens when we preach that cannot be controlled by the preachers or listeners. In this article, I discuss the concept of uncontrollability in Hartmut Rosa’s scholarly contributions and mystery in the work of John de Gruchy. I then discuss four Christmas sermons of the Archbishop of Cape Town, Thabo Makgoba, in search of the mystery of uncontrollability. In trying to understand preaching that resonates, I ask: How does the preaching event reflect the aspects of uncontrollability and transcendence in Archbishop Makgoba’s sermons? Archbishop Makgoba is known for his thought-provoking sermons that often delve into complex issues. The mystery in his sermons lies in his ability to explore profound spiritual concepts and connect them to everyday life. He uses metaphorical language to convey deeper meanings, leaving room for interpretation and contemplation. The mystery in his sermons also stems from his engagement with the unknown aspects of faith and the divine, encouraging his audience to grapple with the mysteries of existence.
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- 2024
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25. Synthesis and crystal structure of sodium (ethane-1,2-diyl)bis[(3-methoxypropyl)phosphinodithiolate] octahydrate
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Bryan P. Nell, David R. Tyler, Lev N. Zakharov, and Dean H. Johnston
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dithiophosphinate ,phosphinodithiolate ,crystal structure ,Crystallography ,QD901-999 - Abstract
The title compound, catena-poly[[triaquasodium]-di-μ-aqua-[triaquasodium]-μ-(ethane-1,2-diyl)bis[(3-methoxypropyl)phosphinodithiolato]], [Na2(C10H22O2P2S4)(H2O)8]n, crystallizes in the triclinic space group P1. The dianionic [CH3O(CH2)3P(=S)(S—)CH2CH2P(=S)(S—)(CH2)3OCH3]2− ligand fragments are joined by a dicationic [Na2(H2O)8]2+ cluster that includes the oxygen of the methoxypropyl unit of the ligand to form infinite chains.
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- 2024
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26. How women living with HIV in the UK manage infant-feeding decisions and vertical transmission risk – a qualitative study
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Kasadha, Bakita, Hinton, Lisa, Tariq, Shema, Nyatsanza, Farai, Namiba, Angelina, Freeman-Romilly, Nell, and Rai, Tanvi
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- 2024
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27. Persistent enrichment of multidrug-resistant Klebsiella in oral and nasal communities during long-term starvation
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Liu, Jett, Spencer, Nell, Utter, Daniel R., Grossman, Alex S., Lei, Lei, dos Santos, Nídia Castro, Shi, Wenyuan, Baker, Jonathon L., Hasturk, Hatice, He, Xuesong, and Bor, Batbileg
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- 2024
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28. Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling
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Saunders, Nell, Monel, Blandine, Cayet, Nadège, Archetti, Lorenzo, Moreno, Hugo, Jeanne, Alexandre, Marguier, Agathe, Buchrieser, Julian, Wai, Timothy, Schwartz, Olivier, and Fréchin, Mathieu
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- 2024
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29. Mixed-method evaluation study of a targeted mass drug administration of long-acting anti-malarials among children aged 3 months to 15 years in the Bossangoa sub-prefecture, Ouham, Central African Republic, during the COVID-19 pandemic
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Robinson, Eve, Ouabo, Adelaide, Rose, Letitia, van Braak, Felipe, Vyncke, Jorieke, Wright, Roberto, Gray, Nell, Sakama, Narcisse Simon, Aboukar, Emmanuel Joao, Fierte, Methode Mberyo, Woinzoukou, Daniel, Ewers, Linn, Serpande, Christian, Stein, Susanne, Van Boetzelaer, Elburg, Kpahina, Odilon Auguste, Sabe, Sosthene Constant, Rao, Bhargavi, and Kuehne, Anna
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- 2024
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30. “We decided together”: a qualitative study about women with HIV navigating infant-feeding decisions with the father of their children
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Kasadha, Bakita, Tariq, Shema, Freeman-Romilly, Nell, Pope, Catherine, Namiba, Angelina, Nyatsanza, Farai, Hinton, Lisa, and Rai, Tanvi
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- 2024
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31. The nature of heterogeneity in the context of distributed health-care information systems
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Nell, J. G.
- Published
- 2003
32. Internet commerce for manufacturing data staging
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Nell, J. G.
- Published
- 2000
33. H Is for Home: Supporting Foundational Literacy Skills
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Duke, Nell K.
- Abstract
Teachable moments--opportunities to help children learn foundational reading skills--happen every day within homes and communities. These moments can be used to complement the systematic instruction children should be receiving at school (preschool and early elementary school). This article discusses ways to take advantage of teachable moments.
- Published
- 2023
34. The Colorado Ultraviolet Transit Experiment (CUTE) Mission Overview
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France, Kevin, Fleming, Brian, Egan, Arika, Desert, Jean-Michel, Fossati, Luca, Koskinen, Tommi T., Nell, Nicholas, Petit, Pascal, Vidotto, Aline A., Beasley, Matthew, DeCicco, Nicholas, Sreejith, Aickara Gopinathan, Suresh, Ambily, Baumert, Jared, Cauley, P. Wilson, DAngelo, Carolina Villarreal, Hoadley, Keri, Kane, Robert, Kohnert, Richard, Lambert, Julian, and Ulrich, Stefan
- Subjects
Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Earth and Planetary Astrophysics - Abstract
Atmospheric escape is a fundamental process that affects the structure, composition, and evolution of many planets. The signatures of escape are detectable on close-in, gaseous exoplanets orbiting bright stars, owing to the high levels of extreme-ultraviolet irradiation from their parent stars. The Colorado Ultraviolet Transit Experiment (CUTE) is a CubeSat mission designed to take advantage of the near-ultraviolet stellar brightness distribution to conduct a survey of the extended atmospheres of nearby close-in planets. The CUTE payload is a magnifying NUV (2479~--~3306 Ang) spectrograph fed by a rectangular Cassegrain telescope (206mm x 84mm); the spectrogram is recorded on a back-illuminated, UV-enhanced CCD. The science payload is integrated into a 6U Blue Canyon Technology XB1 bus. CUTE was launched into a polar, low-Earth orbit on 27 September 2021 and has been conducting this transit spectroscopy survey following an on-orbit commissioning period. This paper presents the mission motivation, development path, and demonstrates the potential for small satellites to conduct this type of science by presenting initial on-orbit science observations. The primary science mission is being conducted in 2022~--~2023, with a publicly available data archive coming on line in 2023., Comment: 12 pages, 5 figures, AJ - accepted
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- 2023
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35. The on-orbit performance of the Colorado Ultraviolet Transit Experiment (CUTE) Mission
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Egan, Arika, Nell, Nicholas, Suresh, Ambily, France, Kevin, Fleming, Brian, Sreejith, A. G., Lambert, Julian, and DeCicco, Nicholas
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Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
We present the on-orbit performance of the Colorado Ultraviolet Transit Experiment ($CUTE$). $CUTE$ is a 6U CubeSat that launched on September 27th, 2021 and is obtaining near-ultraviolet (NUV, 2480 A -- 3306 A) transit spectroscopy of short-period exoplanets. The instrument comprises a 20 cm $\times$ 8 cm rectangular Cassegrain telescope, an NUV spectrograph with a holographically ruled aberration-correcting diffraction grating, and a passively cooled, back-illuminated NUV-optimized CCD detector. The telescope feeds the spectrograph through an 18$'$ $\times$ 60$''$ slit. The spacecraft bus is a Blue Canyon Technologies XB1, which has demonstrated $\leq$ 6$''$ jitter in 56% of $CUTE$ science exposures. Following spacecraft commissioning, an on-orbit calibration program was executed to characterize the $CUTE$ instrument's on-orbit performance. The results of this calibration indicate that the effective area of $CUTE$ is $\approx$ 19.0 -- 27.5 cm$^{2}$ and that the average intrinsic resolution element is 2.9 A across the bandpass. This paper describes the measurement of the science instrument performance parameters as well as the thermal and pointing characteristics of the observatory.
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- 2023
- Full Text
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36. One Year Later, Campuses Ban Pro-Palestine Protests 'In All But Name': Quietly rolled out over the summer, college and university policies target the student movement for Palestine
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Srinath, Nell
- Subjects
Israel-Arab conflicts -- Demonstrations and protests ,Student movements -- Laws, regulations and rules ,Universities and colleges -- Laws, regulations and rules -- United States ,Government regulation ,Political science - Abstract
For students at the University of Michigan in Ann Arbor, a die-in is nothing new. In November 2023, one month into Israel's siege and bombardment of the Gaza Strip, a [...]
- Published
- 2024
37. Extragonadal immature teratoma of the uterus
- Author
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Katherine Jane C. Chua, Maryam Ali, Alice Barr, Rebecca Brooks, and Nell V. Suby
- Subjects
Extragonadal malignant immature teratoma ,Minimally invasive primary debulking ,Chemosensitive germ cell tumor ,Gynecology and obstetrics ,RG1-991 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Background: With fewer than 20 cases of extragonadal teratomas since 1929, treatment guidelines remain unclear. Case Presentation: A 27-year-old nulliparous female presented with vaginal bleeding and malodorous discharge. Transvaginal ultrasound and pelvic MRI revealed a 4 cm prolapsing echogenic cervical mass that was FDG avid on PET CT. Biopsy confirmed a grade 1 polypoid immature teratoma arising from either the uterus or cervix. She underwent a total laparoscopic hysterectomy, bilateral salpingectomy, omentectomy, and primary optimal tumor debulking to R0. Bilaterally ovaries appeared grossly normal and were preserved. On final pathology, the patient was staged using FIGO ovarian cancer criteria as Stage IIIA2 grade 2 immature teratoma of the uterus. The patient received three cycles of bleomycin, etoposide, and cisplatin. The patient is 11 months post-surgery and currently undergoing surveillance. Conclusion: Given the rarity of uterine immature teratomas, management of this case was extrapolated from existing recommendations for immature ovarian teratomas. Unlike in prior case reports where surgical approach was via an exploratory laparotomy, our patient underwent optimal debulking via minimally invasive surgery with ovarian preservation and adjuvant chemotherapy. Given the chemosensitive nature of germ cell tumors, further fertility sparing options for extragonadal immature teratoma may be further explored.
- Published
- 2025
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38. The Autonomous Data Reduction Pipeline for the CUTE Mission
- Author
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Sreejith, A. G., Fossati, Luca, Ambily, S., Egan, Arika, Nell, Nicholas, France, Kevin, Fleming, Brian T., Haas, Stephanie, Chambliss, Michael, DeCicco, Nicholas, and Steller, Manfred
- Subjects
Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The Colorado Ultraviolet Transit Experiment (CUTE) is a 6U NASA CubeSat carrying on-board a low-resolution, near-ultraviolet (2479-3306 A) spectrograph. It has a Cassegrain telescope with a rectangular primary to maximize the collecting area, given the shape of the satellite bus, and an aberration correcting grating to improve the image quality, and thus spectral resolution. CUTE, launched on the 27th of September 2021 to a Low Earth Orbit, is designed to monitor transiting extra-solar planets orbiting bright, nearby stars to improve our understanding of planet atmospheric escape and star-planet interaction processes. We present here the CUTE autONomous daTa ReductiOn pipeLine (CONTROL), developed for reducing CUTE data. The pipeline has been structured with a modular approach, which also considers scalability and adaptability to other missions carrying on-board a long-slit spectrograph. The CUTE data simulator has been used to generate synthetic observations used for developing and testing the pipeline functionalities. The pipeline has been tested and updated employing ight data obtained during commissioning and initial science operations of the mission., Comment: Accepted for publication in the Publications of the Astronomical Society of the Pacific
- Published
- 2022
- Full Text
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39. Expanding Accurate Person Recognition to New Altitudes and Ranges: The BRIAR Dataset
- Author
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Cornett III, David, Brogan, Joel, Barber, Nell, Aykac, Deniz, Baird, Seth, Burchfield, Nick, Dukes, Carl, Duncan, Andrew, Ferrell, Regina, Goddard, Jim, Jager, Gavin, Larson, Matt, Murphy, Bart, Johnson, Christi, Shelley, Ian, Srinivas, Nisha, Stockwell, Brandon, Thompson, Leanne, Yohe, Matt, Zhang, Robert, Dolvin, Scott, Santos-Villalobos, Hector J., and Bolme, David S.
- Subjects
Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
Face recognition technology has advanced significantly in recent years due largely to the availability of large and increasingly complex training datasets for use in deep learning models. These datasets, however, typically comprise images scraped from news sites or social media platforms and, therefore, have limited utility in more advanced security, forensics, and military applications. These applications require lower resolution, longer ranges, and elevated viewpoints. To meet these critical needs, we collected and curated the first and second subsets of a large multi-modal biometric dataset designed for use in the research and development (R&D) of biometric recognition technologies under extremely challenging conditions. Thus far, the dataset includes more than 350,000 still images and over 1,300 hours of video footage of approximately 1,000 subjects. To collect this data, we used Nikon DSLR cameras, a variety of commercial surveillance cameras, specialized long-rage R&D cameras, and Group 1 and Group 2 UAV platforms. The goal is to support the development of algorithms capable of accurately recognizing people at ranges up to 1,000 m and from high angles of elevation. These advances will include improvements to the state of the art in face recognition and will support new research in the area of whole-body recognition using methods based on gait and anthropometry. This paper describes methods used to collect and curate the dataset, and the dataset's characteristics at the current stage.
- Published
- 2022
40. Managing Water Scarcity: A Framework for Fair and Effective Water Right Curtailment in California
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Green Nylen, Nell, Owen, Dave, Harder, Jennifer, Kiparsky, Michael, and Hanemann, Michael
- Subjects
California drought ,California State Water Resources Control Board ,curtailment ,drought ,emergency regulations ,enforcement ,water rights - Abstract
Droughts are becoming more frequent and intense in California. Many California watersheds experience seasonal water scarcity nearly every year. To protect water rights, human health and safety, and the environment from serious harm, California’s State Water Resources Control Board (SWRCB) needs to be able to routinely curtail unlawful water uses. But it has struggled to carry out this basic function, running into resource constraints and technical, legal, and political barriers. This report describes the legal context for and history of curtailments in California. It also recommends actions the SWRCB and State Legislature can take to build a framework for fair and effective curtailment in California.
- Published
- 2023
41. Elektrische Maschinen
- Author
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Hameyer, Kay, Butterweck, Daniel, Driendl, Niklas, Franck, Marius, Groschup, Benedikt, Jansen, Kevin, Leuning, Nora, Mönninghoff, Sebastian, Nell, Martin, Schröder, Michael, Kampker, Achim, editor, and Heimes, Heiner Hans, editor
- Published
- 2024
- Full Text
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42. Contribution of autosomal rare and de novo variants to sex differences in autism
- Author
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Aleksic, Branko, Artomov, Mykyta, Barbosa, Mafalda, Benetti, Elisa, Betancur, Catalina, Biscaldi-Schafer, Monica, Børglum, Anders D., Brand, Harrison, Brusco, Alfredo, Buxbaum, Joseph D., Campos, Gabriele, Cardaropoli, Simona, Carli, Diana, Carracedo, Angel, Chan, Marcus C.Y., Chiocchetti, Andreas G., Chung, Brian H.Y., Collins, Brett, Collins, Ryan L., Cook, Edwin H., Coon, Hilary, Costa, Claudia I.S., Cuccaro, Michael L., Cutler, David J., Daly, Mark J., De Rubeis, Silvia, Devlin, Bernie, Doan, Ryan N., Domenici, Enrico, Dong, Shan, Fallerini, Chiara, Fernández-Prieto, Montserrat, Ferrero, Giovanni Battista, Freitag, Christine M., Fu, Jack M., Gargus, J. Jay, Gerges, Sherif, Giorgio, Elisa, Girardi, Ana Cristina, Guter, Stephen, Hansen-Kiss, Emily, Herman, Gail E., Hertz-Picciotto, Irva, Hougaard, David M., Hultman, Christina M., Jacob, Suma, Kaartinen, Miia, Klei, Lambertus, Kolevzon, Alexander, Kushima, Itaru, Lee, So Lun, Lehtimäki, Terho, Liang, Lindsay, Lintas, Carla, Ljungdahl, Alicia, Lo Rizzo, Caterina, Ludena, Yunin, Maciel, Patricia, Mahjani, Behrang, Maltman, Nell, Manara, Marianna, Manoach, Dara S., Meiri, Gal, Menashe, Idan, Miller, Judith, Minshew, Nancy, Mosconi, Matthew, Nguyen, Rachel, Ozaki, Norio, Palotie, Aarno, Parellada, Mara, Passos-Bueno, Maria Rita, Pavinato, Lisa, Peng, Minshi, Pericak-Vance, Margaret, Persico, Antonio M., Pessah, Isaac N., Puura, Kaija, Reichenberg, Abraham, Renieri, Alessandra, Roeder, Kathryn, Sanders, Stephan J., Sandin, Sven, Satterstrom, F. Kyle, Scherer, Stephen W., Schlitt, Sabine, Schmidt, Rebecca J., Schmitt, Lauren, Schneider-Momm, Katja, Siper, Paige M., Sloofman, Laura, Smith, Moyra, Stevens, Christine R., Suren, Pål, Sutcliffe, James S., Sweeney, John A., Talkowski, Michael E., Tassone, Flora, Teufel, Karoline, Trabetti, Elisabetta, Trajkova, Slavica, Trelles, Maria del Pilar, Wamsley, Brie, Wang, Jaqueline Y.T., Weiss, Lauren A., Yu, Mullin H.C., Yuen, Ryan, Adhya, Deep, Allison, Carrie, Ayeung, Bonnie, Bamford, Rosie, Baron-Cohen, Simon, Bethlehem, Richard, Biron-Shental, Tal, Burton, Graham, Cowell, Wendy, Davies, Jonathan, Floris, Dori, Franklin, Alice, Gabis, Lidia, Geschwind, Daniel, Greenberg, David M., Gu, Yuanjun, Havdahl, Alexandra, Heazell, Alexander, Holt, Rosemary, Hurles, Matthew, Khan, Yumnah, Lai, Meng-Chuan, Lancaster, Madeline, Lombardo, Michael, Martin, Hilary, Martinez, Jose Gonzalez, Mill, Jonathan, Koko, Mahmoud, Niakan, Kathy, Pavlinek, Adam, Polit, Lucia Dutan, Radecki, Marcin, Rowitch, David, Sichlinger, Laura, Srivastava, Deepak, Tsompanidis, Alexandros, Uzefovsky, Florina, Warrier, Varun, Weir, Elizabeth, and Zhang, Xinhe
- Published
- 2025
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43. PFMG2025–integrating genomic medicine into the national healthcare system in France
- Author
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Abadie, Caroline, Abderrahmane, Aldja, Abdous, Ouarda, Abel, Carine, Ackermann, Oanez, Acquaviva, Cécile, Ader, Flavie, Adham, Salma, Adjaoud, Dalila, Afenjar, Alexandra, Aladjidi, Nathalie, Alary, Anne-Sophie, Albarel, Frédérique, Albert, Sabrina, Allard, Lise, Allix, Ingrid, Alunni, Violaine, Amado, Inês F., Amouroux, Cyril, André, Nicolas, Angelini, Chloé, Anheim, Mathieu, Sanfelliz, Ignacio Antolin, Aparicio, Thomas, Arfeuille, Chloé, Arlet, Jean-Benoît, Arnaud, Lionel, Arnaud, Pauline, Arnold, Guilhem, Attie-Bitach, Tania, Aubert-Mucca, Marion, Audo, Isabelle, Audrezet, Marie-Pierre, Auroux, Maxime, Auzanneau, Céline, Ayrignac, Xavier, Ba, Ibrahima, Bachelot, Anne, Bacq, Delphine, Bacrot, Séverine, Bader-Meunier, Brigitte, Baer, Sarah, Baert-Desurmont, Stéphanie, Bal-Theoleyre, Laurence, Balogoun, Ralyath, Baltzinger, Philippe, Banneau, Guillaume, Bar, Claire, Barbet, Audrey, Barcia, Giulia, Barjhoux, Laure, Barlier, Anne, Barlogis, Vincent, Barritault, Marc, Barth, Magalie, Barthod-Malat, Aurore, Baudouin-Cornu, Peggy, Baujat, Geneviève, Baurand, Amandine, Bay, Jacques-Olivier, Beau-Faller, Michèle, Beaudoin, Jean-Christophe, Bellance, Rémi, Bellanné-Chantelot, Christine, Bellera, Carine, Belot, Alexandre, Ben Abdeljelil, Raihane, Ben Sghaier, Rihab, Benadiba, Joy, Benard, Stéphanie, Beneteau, Claire, Benistan, Karelle, Benkerdou, Fouzia, Benkirane, Mehdi, Benoist, Jean-François, Benusiglio, Patrick R., Bergès, Camille, Bergougnoux, Anne, Bernadach, Maureen, Bernard, Emilien, Bernard, Valérie, Bernard, Virginie, Beroug, Dounia, Berrard, Aurélie, Bertherat, Jérôme, Berthet, Pascaline, Berthier, Clotilde, Bertholet-Thomas, Aurélia, Bertocchio, Jean-Philippe, Bertucci, François, Besse, Céline, Besse-Pinot, Elsa, Bessis, Didier, Beuvain, Pauline, Bezieau, Stéphane, Bidart, Marie, Bièche, Ivan, Biehler, Margaux, Bienvenu, Thierry, Bilan, Frédéric, Billon, Clarisse, Binquet, Christine, Bismuth, Elise, Bizaoui, Varoona, Blanc, Pierre, Blanché, Hélène, Blay, Jean-Yves, Bloch, Adrien, Bloch, Gilles, Bloch-Zupan, Agnes, Bocquet, Béatrice, Boedec, Morgane, Boileau, Catherine, Boissinot, Maureen, Boland, Anne, Bolze, Pierre-Adrien, Bonadona, Valérie, Bonastre, Julia, Bonello-Palot, Nathalie, Bonnard, Adeline-Alice, Borie, Raphaël, Botsen, Damien, Bouattour, Mohamed, Bouctot, Marion, Bouhours-Nouet, Natacha, Bouligand, Jérôme, Bouras, Ahmed, Bourgeron, Thomas, Bourges, Jean-Louis, Bourrat, Emmanuelle, Boursier, Guilaine, Bousquet, Guilhem, Bousquet, Philippe-Jean, Boussion, Simon, Boutaud, Lucile, Boutin, Julian, Bouvagnet, Patrice, Bouvattier, Claire, Boyault, Sandrine, Brac de la Perriere, Aude, Brahmi, Mehdi, Brard, Valentine, Brasseur, Mathilde, Brazzalotto, Nadège, Brémond-Gignac, Dominique, Briand-Suleau, Audrey, Briet, Claire, Bringuier, Pierre-Paul, Bris, Céline, Brischoux-Boucher, Elise, Brochard, Karine, Broly, Martin, Brosseau, Laura, Bruel, Ange-Line, Brunelle, Perrine, Bubien, Virginie, Buecher, Bruno, Buffet, Alexandre, Buisson, Adrien, Burglen, Lydie, Des Roziers, Cyril Burin, Burnichon, Nelly, Busa, Tiffany, Cabart, Mathilde, Cabet, Sara, Caille-Benigni, Charlotte, Caillot, Claire, Calvin, Christophe, Cambon-Thomsen, Anne, Cances, Claude, Cantan, Alexandre, Carausu, Liana, Carbasse, Aurélia, Carbonneil, Cédric, Cariou, Bertrand, Caron, Olivier, Carras, Sylvain, Cartalat, Stéphanie, Cassinari, Kévin, Castelle, Martin, Castéra, Laurent, Castinetti, Frédéric, Catteau, Julie, Caumes, Roseline, Caux, Aurélien, Cavaillé, Mathias, Cavé, Hélène, Caye-Eude, Aurélie, Cazeneuve, Cécile, Celse, Tristan, Celton, Noémie, Cenni, Camille, Cévost, Jasmin, Chaabna, Rania, Chabrol, Brigitte, Challet, Ilyas, Chalumeau, Clélia, Chambon, Pascal, Chansavang, Albain, Chanson, Jean-Baptiste, Chapelant, Sébastien, Charbit-Henrion, Fabienne, Charles, Perrine, Charrière, Sybil, Charron, Philippe, Chassaing, Nicolas, Chatron, Nicolas, Chaumette, Boris, Chaussain, Catherine, Chaussenot, Annabelle, Cheillan, David, Chenavier, Olivier, Chesneau, Bertrand, Chevalier, Louise-Marie, Chomienne, Christine, Chougnet, Cécile, Christin-Maitre, Sophie, Chuet, Marine, Clappier, Emmanuelle, Clet, Johanna, Cloteau, Mélanie, Cluzeau, Thomas, Cogan, Guillaume, Cogné, Benjamin, Cohen, Alicia, Cohen, Camille, Cohen-Haguenauer, Odile, Cohen-Solal, Martine, Colas, Chrystelle, Colin, Estelle, Collet, Corinne, Collin-Chavagnac, Delphine, Colliou, Eloïse, Collonge-Rame, Marie-Agnès, Colmard, Maxime, Coopman, Stéphanie, Coppin, Lucie, Coquan, Elodie, Cormier-Daire, Valérie, Corradini, Nadège, Corsini, Carole, Cossée, Mireille, Coste, Thibault, Cotteret, Sophie, Cottet, Rachel, Coubes, Christine, Coulet, Florence, Couque, Nathalie, Couratier, Philippe, Courbebaisse, Marie, Courbette, Olivier, Courdier, Cécile, Coursimault, Juliette, Courtin, Thomas, Courtois, Lucien, Coury, Fabienne, Coutos-Thévenot, Laure, Coutton, Charles, Creveaux, Isabelle, Crickx, Etienne, Crivelli, Louise, Cuggia, Marc, Cuisset, Laurence, Curcio, Hubert, Curie, Aurore, Cusin, Veronica, Da Costa, Noémie, Da Cruz, Lionel, Dahlen, Eric, Dardenne, Antoine, Dauriat, Benjamin, Dausse, Nell, De Becdelièvre, Alix, De Fraipont, Florence, De La Cruz, Elisa, De la Motte Rouge, Thibault, De Montgolfier, Sandrine, De Pauw, Antoine, De Reyniès, Aurélien, De Sainte Agathe, Jean-Madeleine, De Tayrac, Marie, Defachelles, Anne-Sophie, Degaud, Michaël, Deiller, Caroline, Delabesse, Eric, Delachaux, Leslie, Delahaye-Duriez, Andrée, Deleuze, Jean-François, Delhomelle, Hélène, Delmas, Christelle, Delnatte, Capucine, Delorme, Catherine, Delorme, Richard, Demeer, Bénédicte, Demilly, Caroline, Denizeau, Philippe, Denjoy, Isabelle, Denommé-Pichon, Anne-Sophie, Depienne, Christel, Derive, Nicolas, Dervillé, Flora, Portes, Vincent Des, Desguerre, Isabelle, Desnous, Béatrice, Desseignes, Camille, Devillard, Françoise, Deville, Manjula, Dewulf-Pasz, Nelly, Dhaenens, Claire-Marie, Dietrich, Klaus, Dieux, Anne, Diop, Mody, Disse, Emmanuel, Djaber, Samir, Cao, Christine Do, Dollfus, Hélène, Domenach, Louis, Donadieu, Jean, Donadille, Bruno, Dougé, Aurore, Dreyfus, Hélène, Drunat, Séverine, Dubois-Laforgue, Danièle, Dubourg, Christele, Dubucs, Charlotte, Dubus, Jean-Christophe, Duchmann, Matthieu, Ducray, François, Ducrotverdun, Marion, Duffaud, Florence, Duffourd, Yannis, Dufour, William, Duhil de Bénazé, Gwénaelle, Dulac, Yves, Dunand, Olivier, Dunoyer de Segonzac, Denis, Dupain, Célia, Duployez, Nicolas, Dupré, Anaïs, Dupré, Aurélien, Dupuis-Girod, Sophie, Duquet, Romain, Durand, Alice, Durand, Benjamin, Durand-Zaleski, Isabelle, Durando, Xavier, Durr, Alexandra, Eberst, Lauriane, Edery, Patrick, Egloff, Matthieu, El Chehadeh, Salima, El Khattabi, Laïla, Engel, Camille, Entresangle, Mathilde, Espérou, Hélène, Esselin, Florence, Etancelin, Pascaline, Evrevin, Clémence, Ewenczyk, Claire, Eychene, Alain, Eychenne, Thomas, Ezaru, Andra, Fabry, Vincent, Faivre, Laurence, Faoucher, Marie, Faure, Clémentine, Fauré, Julien, Fauret-Amsellem, Anne-Laure, Feigerlova, Eva, Feillet, François, Fenwarth, Laurène, Férec, Claude, Fergelot, Patricia, Ferrari, Anthony, Ferraro-Peyret, Carole, Feugeas, Jean-Paul, Fieschi, Claire, Fievet, Alice, Fila, Marc, Fillatre, Rémi, Filser, Mathilde, Fin, Bertrand, Fiore, Mathieu, Firmin, Nelly, Flandrin-Gresta, Pascale, Flechon, Aude, Fournier, Benjamin, Fragny, Cécile, Francois-Heude, Marie-Céline, Francou, Bruno, Frébourg, Thierry, Fressart, Véronique, Frétigny, Mathilde, Funalot, Benoit, Fusaro, Mathieu, Gaignard, Pauline, Gandjbakhch, Estelle, Ganne, Benjamin, Garde, Aurore, Gatinois, Vincent, Gaucher, Céline, Gaudillat, Léa, Gaulard, Philippe, Gauthier, Lucas, Gay-Bellile, Mathilde, Geneste, Damien, Geneviève, David, Genin, Emmanuelle, Genoux, Sandrine, Geoerger, Birgit, Geoffroy, Véronique, Georget, Mathieu, Gérard, Bénédicte, Gertych, Witold, Halem, Souad Gherbi, Ghorab, Karima, Gille, Romane, Gillet, Charlène, Gillibert-Yvert, Marion, Gilly, Olivier, Gimenez-Roqueplo, Anne-Paule, Giraud, Sophie, Girerd, Barbara, Girodon, François, Glazunova, Olga, Gobert, Delphine, Goizet, Cyril, Gokce-Samar, Zeynep, Golmard, Lisa, Gomez-Roca, Carlos, Gonzales, Emmanuel, Gorce, Magali, Gorenstein, Marie-Clémence, Gorrichon, Kévin, Gottrand, Frédéric, Gouas, Laetitia, Gourdon, Stéphanie, Gourdy, Pierre, Gouronc, Aurélie, Goursaud, Claire, Gousse, Gaëlle, Gouy, Evan, Goze-Martineau, Odile, Gozlan, Diane, Grabli, David, Gras, Margaux, Grelet, Maude, Gressin, Laetitia, Grivel, Nathalie, Grotto, Sarah, Grouthier, Virginie, Grunenwald, Solange, Grunewald, Olivier, Gueguen, Paul, Guérin, Cécile, Guerrot, Anne-Marie, Guey, Stéphanie, Guffon, Nathalie, Guichet, Agnès, Guièze, Romain, Guillaud-Bataille, Marine, Guillemin, Francis, Guillerm, Erell, Guillermin, Yann, Guillet-Pichon, Virginie, Guillou, Isabelle, Guimbaud, Rosine, Guimier, Anne, Guissart, Claire, Guittet, Eric, Guy, Nathalie, Hadchouel, Alice, Abdallah, Hamza Hadj, Hadj-Rabia, Smail, Hadjadj, Samy, Hage-Sleiman, Mehdi, Haioun, Corinne, Halawi, Sara, Hamza, Abderaouf, Hanau, Perrine, Hanna, Nadine, Harbuz, Radu, Hardy, Gaëlle, Hauspie, Carine, Hayette, Sandrine, Heard, Jean-Michel, Heiblig, Maël, Heide, Solveig, Heidet, Laurence, Henry, Marcia, Hentgen, Véronique, Héron, Bénédicte, Héron, Delphine, Hervé, Dominique, Herzig, Anthony, Hirsch, Pierre, Hommais, Antoine, Honnorat, Jérôme, Horta, Edgar, Houdayer, Claude, Houillier, Pascal, Huet, Sarah, Hugot, Jean-Pierre, Huguenin, Yoann, Humbert, Marc, Humbert-Asensio, Marie-Laure, Huot, Laure, Ifrah, Norbert, Illouz, Frédéric, Imbard, Apolline, Imbert-Bouteille, Marion, Isambert, Nicolas, Isidor, Bertrand, Italiano, Antoine, Itzykson, Raphaël, Jaillard, Sylvie, Jamilloux, Yvan, Janin, Alexandre, Januel, Louis, Javelot-Jacquelin, Cécile, Jeanne, Médéric, Jedraszak, Guillaume, Jéru, Isabelle, Jeunemaitre, Xavier, Jeziorski, Eric, Jobic, Florence, Joly, Philippe, Jonard, Laurence, Jondeau, Guillaume, Jones, Natalie, Jouannic, Jean-Marie, Jouinot, Anne, Jouk, Pierre-Simon, Jourdy, Yohann, Jousselin, Kévin, Jouvenceau, Anne, Jubert, Charlotte, Julia, Sophie, Jurquet, Anne-laure, Juven, Aurélien, Kamal, Maud, Kantapareddy, Pascal, Kaphan, Elsa, Karayan-Tapon, Lucie, Kasper, Edwige, Kerbellec, Lara, Keren, Boris, Khalifa, Emmanuel, Van Kien, Philippe Khau, Kheddouci, Sihem, Kientz, Caroline, Kim, Rathana, Knapke, Antjie, Koenig, Michel, isabelle Kone, Konyukh, Marina, Kormann, Raphaël, Kossorotoff, Manoelle, Kuentz, Paul, Kyndt, Florence, L'Haridon, Anaïs, Labrune, Philippe, Lackmy, Marilyn, Lacombe, Didier, Lacroix, Ludovic, Laffargue, Fanny, Lahlou, Ghizlene, Laizet, Yec'han, Lambert, Laetitia, Lamoril, Jérôme, Lamouroux, Audrey, Landais, Emilie, Landman, Samuel, Landry, Elise, Lapillonne, Hélène, Lapointe, Anne-Sophie, Larcher, Lise, Lardeux, Pierre, Largeaud, Laetitia, Larger, Etienne, Larrouquere, Louis, Lasolle, Hélène, Lasseaux, Eulalie, Latypova, Xenia, Laurens, Tiphany, Laurent, Camille, Laurent-Puig, Pierre, Lautrette, Géraldine, Lauvray, Thomas, Lavallart, Benoît, Lavenu-Bombled, Cécile, Laverdure, Noémie, Le Bris, Yannick, Le Chalony, Catherine, Le Du, Nathalie, Le Folgoc, Gaëlle, Le Gac, Gerald, Le Gall, Jessica, Le Guillou, Edouard, Le Guillou, Xavier, Le Guyader, Gwenaël, Le Ray, Maryannick, Le Saux, Olivia, Le Tourneau, Christophe, Lebecque, Benjamin, Lebellec, Loïc, Lebigot, Elise, Leblond, Pierre, Leboulanger, Nicolas, Lebras, Laure, Lebre, Anne-Sophie, Lebreton, Louis, Lecoquierre, François, Lefebvre, Mathilde, Legendre, Marine, Leglise, Camille, Legrand, Clémentine, Lehalle, Daphné, Lejeune, Catherine, Lemaitre, Christine, Leman, Raphaël, Lepage, Mathis, Lermine, Alban, Leroy, Karen, Lesca, Gaëtan, Lesieur-Sebellin, Marion, Letexier, Mélanie, Lethimonnier, Franck, Levaillant, Lucie, Levy, Jonathan, Levy, Yves, Lévy, Pascale, Lhermitte, Ludovic, Linglart, Agnès, Lionnet, Clément, Livon, Doriane, Lode, Laurence, Lodin, Magalie, Lopez, Jonathan, Lopez, Maureen, Lortholary, Alain, Louha, Malek, Louvrier, Camille, Ludwig, Thomas E., Luvet, Auriane, Lyonnet, Stanislas, Makowski, Caroline, Malan, Valérie, Mallaret, Martial, Mallet, Delphine, Mallet, Stéphanie, Malphettes, Marion, Manaud, Nathalie, Mancini, Pierre, Manfredi, Sylvain, Manouvrier, Sylvie, Mansard, Luke, Mansard, Sandrine, Mansour-Hendili, Lamisse, Mansuy, Ludovic, Maquet, Julien, Marçais, Ambroise, Marceau-Renaut, Alice, Marec-Berard, Perrine, Marelli, Cécilia, Marenne, Gaëlle, Marey, Isabelle, Margier, Jennifer, Margot, Henri, Marie, Guillaume, Marin, Victor, Marisa, Laetitia, Marlin, Sandrine, Marquant, Emeline, Marquet, Valentine, Marsili, Luisa, Martin, Amaury, Martinerie, Laetitia, Maruani, Anna, Marzin, Pauline, Massard, Christophe, Masson, Emmanuelle, Mathieu, Flavie, Mathieu, Marion, Mathoulin-Pelissier, Simone, Matthieu, Flore, Mauras, Mathilde, Maureille, Aurélien, Mazel, Benoit, Mazeres, Mary, Leer, Anne Mc, Melki, Isabelle, Menassa, Rita, Méneret, Aurélie, Menjard, Julie, Mercier, Anne, Merieau, Elodie, Merlin, Marie-Sophie, Merlio, Jean-Philippe, Meslier, Cécile, Mesnard, Laurent, Mestre-Godin, Sandrine, Metay, Corinne, Meunier, Sandrine, Meyer, Pierre, Michaud, Vincent, Michel-Calemard, Laurence, Mignot, Cyril, Miguet, Marguerite, Millat, Gilles, Mirault, Tristan, Miron de l'Espinay, Albane, Molac, Clémence, Molin, Arnaud, Mondet, Julie, Monin, Faustine, Monin, Pauline, Monneur, Audrey, Monnot, Sophie, Montani, David, Morel, Elodie, Morel, Godelieve, Morel, Valérie, Moretta, Jessica, Morice-Picard, Fanny, Morillon, Lucie, Morin, Carole, Morin-Meschin, Marie-Emmanuelle, Morlat, Philippe, Moshous, Despina, Mouret-Fourme, Emmanuelle, Moussy, Alice, Moutton, Sébastien, Mouzat, Kévin, Muletier, Romane, Muller, Jean, Muller, Marie, Nadaj-Pakleza, Aleksandra, Nambot, Sophie, Nathan, Nadia, Nava, Caroline, Nectoux, Juliette, Netter, Jeanne, Neumann, Florent, Neveu, Julien, Nevière, Zoé, Nguyen, Laetitia, Niclass, Tanguy, Nicolas, Gaël, Nicolas, Laury, Ningarhari, Massih, Nogues, Catherine, Novello, Cécile, Nowak, Frédérique, Odent, Sylvie, Odou, Marie-Françoise, Olaso, Robert, Otmani, Sarah, Ovaert, Caroline, Pacot, Laurence, Pages, Mélanie, Paillard, Catherine, Palmyre, Aurélien, Panagiotakaki, Eleni, Pannard, Myriam, Paoletti, Anne, Papadopoulou, Maria T., Papathanasiou, Matthildi, Paquis, Véronique, Parfait, Béatrice, Paris, Camille, Paris, Clara, Paris, Françoise, Pasmant, Eric, Pasquet, Marlène, Passet, Marie, Pastoret, Cédric, Patat, Olivier, Patay, Léa, Paul, Antoine, Pebrel-Richard, Céline, Peduto, Cristina, Peffault de Latour, Regis, Pegat, Antoine, Pelletier, Annick, Pelletier, Valérie, Pellisson, Fanny, Pennamen, Perrine, Pereira, Victor, Pernin-Grandjean, Julie, Péron, Julien, Perrier, Alexandre, Perrier, Lionel, Perrin, Laurence, Perthus, Isabelle, Petit, Arnaud, Petit, Audrey, Petit, Florence, Petit, François, Petrov, Yuliya, Peyre, Hugo, Philippe, Christophe, Piard, Juliette, Pierre-Noël, Elise, Pierron, Gaëlle, Pimouguet, Clément, Pingault, Véronique, Pinson, Stéphane, Pion, Emmanuelle, Plaisancié, Julie, Planes, Marc, Planté-Bordeneuve, Pauline, Plas, William, Plutino, Morgane, Poignie, Ludivine, Poinsignon, Vianney, Poirée, Marilyne, Pons, Nicolas, Pontier, Bénédicte, Porquet-Bordes, Valérie, Porteret, Camille, Potier, Delphine, Potier, Louis, Pouessel, Damien, Poujade, Laura, Preau, Marie, Preudhomme, Claude, Prieur, Fabienne, Probst, Vincent, Procaccio, Vincent, Prot-Bertoye, Caroline, Prunier, Delphine, Puechberty, Jacques, Pujalte, Mathilde, Qebibo, Leila, Quemener-Redon, Sylvia, Quérée, Isabelle, Quijano-Roy, Susana, Quirin, Nicolas, Racine, Caroline, Raimbault, Sandra, Raimbourg, Judith, Rajaoba, Marine, Rambaud, Thomas, Ramirez, Carole, Ramond, Francis, Ranguin, Kara, Rausell, Antonio, Ravel, Jean-Marie, Ravelli, Claudia, Raverot, Gerald, Ray-Coquard, Isabelle, Raynal, Caroline, Réant, Patricia, Rebours, Vinciane, Redon, Richard, Réguerre, Yves, Reix, Philippe, Renard, Cécile, Renaud, Mathilde, Rendu, John, Renoux, Céline, Rey, Romain, Reynaud, Rachel, Rhinan, Lucie, Riant, Florence, Riccardi, Florence, Richard, Pascale, Ricou, Agathe, Rigalleau, Vincent, Rio, Marlène, Rivière, Axelle, Robelin, Patrick, Robert, Marion, Robert, Thomas, Rohmer, Barbara, Romanet, Pauline, Romoli, Arnaud, Rondeau, Sophie, Rooryck, Caroline, Roquelaure, Bertrand, Rosain, Jérémie, Rossi, Massimiliano, Rossignol, Sylvie, Rothenbuhler, Anya, Rouel, Nadège, Rouillon, Marine, Roux, Anne-Francoise, Roux-Buisson, Nathalie, Rouzier, Cécile, Roze, Emmanuel, Ruaud, Lyse, Ruault, Valentin, Ruysschaert, Claire, Saada, Esma, Saadi - Ait El Mkadem, Samira, Saandi, Thoueiba, Sabour, Niki, Sacconi, Sabrina, Saffroy, Raphaël, Safraou, Hana, Saillour, Virginie, Pierre, Aude Saint, Saint-Martin, Cécile, Saintigny, Pierre, Salaun, Gaëlle, Salgado, David, Salle, Laurence, Samuel, Didier, Sanlaville, Damien, Sapey-Triomphe, Laure, Sarnacki, Sabine, Sarrazin, Elisabeth, Sarret, Catherine, Satre, Véronique, Saugier-Veber, Pascale, Saultier, Paul, Saumet, Laure, Schaefer, Elise, Scheyer, Nicolas, Schiff, Isabelle, Schleiermacher, Gudrun, Schleinitz, Nicolas, Schluth-Bolard, Caroline, Schneider, Anouck, Schwartz, Bertrand, Sebaoun, Jean-Marc, Serey-Gaut, Margaux, Serrier, Hassan, Servais, Aude, Serveaux-Dancer, Marine, Sevenet, Nicolas, Seyve, Antoine, Sibony-Cohen, Alicia, Sicre de Fontbrune, Flore, Sigaudy, Sabine, Sigaux, François, Simaga, Fatoumata, Simmet, Victor, Simon, Pauline, Simon, Sophie, Sirveaux, François, Smol, Thomas, Solé, Guilhem, Soler, Gwendoline, Solignac, Pauline, Soriani, Marie-Hélène, Soubeyran, Isabelle, Soulier, Jean, Spelle, Laurent, Sperelakis-Beedham, Brian, Spinazzi, Marco, Spodenkiewicz, Marta, Spraul, Anne, Squiban, Barbara, Srikaran, Arunya, Steffann, Julie, Stetco, Anamaria, Stoeva, Radka, Stojkovic, Tanya, Stoppa-Lyonnet, Dominique, Suarez, Felipe, Sujobert, Pierre, Svahn, Juliette, Ta, Minh-Chau, Tabet, Anne-Claude, Tachon, Gaëlle, Tallegas, Matthias, Tallet, Anne, Tambourin, Pierre-Edmond, Tandonnet, Julie, Tardy, Véronique, Tavernier, Emmanuelle, Tchernitchko, Dimitri, Teillon-Berranger, Marie-Hélène, Tenenbaum, Julie, Teoli, Jordan, Tessarech, Marine, Tessoulin, Benoit, Tharreau, Mylène, Thauvin-Robinet, Christel, Theou-Anton, Nathalie, Thevenon, Julien, Thomas, Anne, Thomas, Laure, Thomas, Quentin, Thomas-Teinturier, Cécile, Tieulie, Nathalie, Tinat, Julie, Tlemsani, Camille, Tondeur, Sylvie, Tosca, Lucie, Tosi, Diego, Tougeron, David, Touraine, Phlippe, Tournier-Lasserve, Elisabeth, Toutain, Annick, Mau-Them, Frédéric Tran, Tranchant, Christine, Trédan, Olivier, Trimouille, Aurélien, Trochu, Jean-Noël, Tronel, Vincent, Trouba, Cécile, Truchetet, Marie-Elise, Truffaux, Nathalène, Tsalamlal, Amel, Turlotte, Edouard, Turon, Violette, Tusseau, Maud, Uhrhammer, Nancy, Vaché, Christel, Valence, Stéphanie, Valentin, Thibaud, Valero, René, Valleix, Sophie, Vallet, Marion, Vanacker, Hélène, Vande-Perre, Pierre, Vandenbrouck, Yves, Vanlerberghe, Clémence, Vargas-Poussou, Rosa, Vatier, Camille, Vauchel, Vincent, Vaur, Dominique, Velo-Suarez, Lourdes, Venat, Laurence, Vera, Gabriella, Verebi, Camille, Verley, Célia, Verlingue, Loïc, Verny, Christophe, Veronese, Lauren, Verotte, Nelly, Verret, Benjamin, Vial, Yoann, Vialard, Francois, Viari, Alain, Vidailhet, Marie, Vidaud, Dominique, Vidaud, Michel, Vignes, Stéphane, Vigouroux, Clothilde, Villard, Laurent, Villeneuve, Laurent, Villié, Patricia, Villy, Marie-Charlotte, Vinauger, Lara, Vinceneux, Armelle, Vincenot, Anne, Vinciguerra, Christine, Vitobello, Antonio, Vourc'h, Patrick, Vozy, Aurore, Vuillaume-Winter, Marie-Laure, Vuillaumier-Barrot, Sandrine, Wahbi, Karim, Wallet, Cédrick, Walter, Thomas, Walther-Louvier, Ulrike, Watson, Sarah, Waymel, Anne-Christine, Weinhard, Sara, Wicker, Camille, Willems, Marjolaine, Wourms, Justine, Wyrebski, Antoine, Yauy, Kévin, Zaidan, Mohamad, Zaloszyc, Ariane, Zattara, Hélène, Zawadzki, Christophe, and Ziegler, Alban
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- 2025
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44. The intersection of race and class: Neighborhood socio-economic status and fatal pedestrian and bicycle collisions by race/ethnicity
- Author
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Gibbons, Joseph, Appleyard, Bruce, Honey, Megan, and Ahangarfabrik, Nell
- Published
- 2025
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45. Examining message framing in a higher education crisis: A qualitative analysis of organizational perspectives and media portrayals
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Huang-Horowitz, Nell C. and Smith, Andrea M.
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- 2025
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46. Can foreign aid influence the level of industrialization in African countries?
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Rex Kweku Awuku Asiama and Kevin Nell
- Subjects
Foreign aid ,manufacturing ,industrialisation ,Africa ,C23 ,E60 ,Finance ,HG1-9999 ,Economic theory. Demography ,HB1-3840 - Abstract
AbstractCapital inflows, such as foreign aid, can serve as a means to enhance infrastructure development in developing countries. This suggests that foreign aid might have an impact on the level of industrialization in African nations. While existing studies indicate that foreign aid can affect the competitiveness of the manufacturing sector by appreciating the real exchange rate, the veracity of this claim relies on empirical evidence. This paper explores the influence of aid on manufacturing value added using time-series data spanning from 1990 to 2018 for 27 African countries. Employing a panel vector autoregression technique and generating associated impulse response functions, the study scrutinizes the interactions between foreign aid and manufacturing. The analysis is conducted on both the full dataset and subsamples disaggregated based on the income levels of countries. The results indicate that foreign aid acts as a stimulus for manufacturing, primarily through a sustained depreciation of the real exchange rate. This finding holds true for both the overall dataset and the subset of low-income countries. The study attributes this phenomenon to the strategic utilization of aid to enhance infrastructure, leading to a reduction in the price of non-tradables relative to tradables. Consequently, this enhances the profitability and output capacity of the manufacturing sector in African countries. In essence, the results suggest that foreign aid plays a role in influencing or stimulating industrialization in African countries. The study concludes with a discussion on the implications of these findings for industrial policy in African nations.
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- 2024
- Full Text
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47. Embodied and hybrid pedagogies
- Author
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I. Nell
- Subjects
Embodies pedagogies ,Glocal learning ,Ecumenical tours ,Experimental learning ,Christianity ,BR1-1725 ,Practical religion. The Christian life ,BV4485-5099 - Abstract
This article aims to explore ecumenical tours as one example of glocal learning and as a case in point. Making use of the central concepts of embodied and hybrid pedagogies as hermeneutical lenses, the main research question is: Does the exposure of students through ecumenical tours, as part of the Master of Divinity programme, foster embodied and hybrid pedagogies, and if so, in what ways? Factors at play in ecumenical exposure include the content of the programme, the diversity of the student population, as well as the reflective and participatory practices of teaching, learning, and assessing in lived faith contexts. The article especially emphasises a one-day pilgrimage among the lived faith practices.
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- 2024
- Full Text
- View/download PDF
48. Isolation-protocol, characterization, and in-vitro performance of equine umbilical vein endothelial cells
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Ulrike Lessiak, Maria Melchert, Ingrid Walter, Stefan Kummer, Barbara Nell, Waltraud Tschulenk, and Barbara Pratscher
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EqUVEC ,angiogenesis ,equine endothelial cells ,immunohistology ,TEM ,cell culture ,Veterinary medicine ,SF600-1100 - Abstract
Angiogenesis plays a crucial role in various physiological and pathological conditions. However, research in equine angiogenesis is relative limited, necessitating the development of suitable in-vitro models. To effectively analyze angiogenesis in-vitro, it is essential to target the specific cells responsible for this process, namely endothelial cells. Human umbilical vein endothelial cells (HUVECs) are one of the most used in vitro models for studying angiogenesis in humans. Serving as an equivalent to HUVECs, we present a comprehensive isolation protocol for equine umbilical vein endothelial cells (EqUVECs) with relatively minimal requirements, thereby enhancing accessibility for researchers. Umbilical cords obtained from five foals were used to isolate endothelial cells, followed by morphological and immunohistochemical identification. Performance of the cells in various assays commonly used in angiogenesis research was studied. Additionally, EqUVEC expression of vascular endothelial growth factor (VEGF) was assessed using ELISA. EqUVECs exhibited endothelial characteristics, forming a homogeneous monolayer with distinctive morphology. Immunohistochemical staining confirmed positive expression of key endothelial markers including von Willebrand factor (vWF), CD31, and vascular endothelial growth factor receptor-2 (VEGFR-2). Furthermore, performance assessments in in-vitro assays demonstrated the viability, proliferation, migration, tube formation and VEGF-expression capabilities of EqUVECs. The findings suggest that EqUVECs are a promising in-vitro model for studying equine angiogenesis, offering a foundation for further investigations into equine-specific vascular processes and therapeutic interventions.
- Published
- 2024
- Full Text
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49. ASC speck serum concentrations, a component of sterile cellular inflammation, are associated with individual cardiopulmonary capacity
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Alexander Kogel, Nell Voßhage, Amirhossein Behzadi, Ulrich Laufs, and Sven Fikenzer
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inflammasome ,CPET ,ASC specks ,oxygen pulse ,cardiopulmonary capacity ,Physiology ,QP1-981 - Abstract
AimsExercise-induced cellular stress and sterile inflammation are of increasing interest. ASC specks are a component of the intracellular NLRP3-inflammasome and can be released into the blood. For example, serum ASC specks are increased after marathon running. We therefore tested whether ASC specks are potentially associated with the individual response to physical training and cardiopulmonary capacity.MethodsWe performed a prospective study in 45 healthy athletes. Blood samples were taken before and after cardiopulmonary exercise testing (CPET). ASC speck concentrations were quantitated using flow cytometry.ResultsBaseline ASC speck levels correlated with clinical parameters of body composition (height, weight, BMI) and parameters of cardiopulmonary performance (peak VO2, peak oxygen pulse, heart rate after exercise). Athletes with lowest baseline ASC speck concentrations have a significantly lower BMI (22.0 ± 1.8 vs. 24.9 ± 1.6 kg/m2), higher heart rate at rest (72 ± 10 vs. 58 ± 10 beats/min), lower peak VO2 (2692 ± 629 vs. 3404 ± 747 mL/min) and lower peak oxygen pulse (15.6 ± 3.4 vs. 20.7 ± 3.5 mL/heart rate). Overall, ASC speck concentrations showed no significant change after CPET (7.0 ± 4.5 vs. 8.0 ± 5.4 ASC specks/µL, p = 0.3). However, subgroup analysis revealed a significant increase in circulating ASC specks in athletes with the lowest baseline values (2.37 ± 0.84 vs. 8.43 ± 7.52 ASC specks/µL, p < 0.05). Athletes with an increase in ASC speck concentrations in response to CPET had a lower peak oxygen pulse compared to those with a decrease (17.1 ± 4.2 vs. 19.8 ± 4.1, p < 0.05).ConclusionLow ASC speck baseline values as well as an increase in response to exercise are associated with lower peak oxygen pulse in healthy athletes.
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- 2024
- Full Text
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50. FaRO 2: an Open Source, Configurable Smart City Framework for Real-Time Distributed Vision and Biometric Systems
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Brogan, Joel, Barber, Nell, Cornett, David, and Bolme, David
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Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Artificial Intelligence ,Computer Science - Cryptography and Security ,Computer Science - Machine Learning - Abstract
Recent global growth in the interest of smart cities has led to trillions of dollars of investment toward research and development. These connected cities have the potential to create a symbiosis of technology and society and revolutionize the cost of living, safety, ecological sustainability, and quality of life of societies on a world-wide scale. Some key components of the smart city construct are connected smart grids, self-driving cars, federated learning systems, smart utilities, large-scale public transit, and proactive surveillance systems. While exciting in prospect, these technologies and their subsequent integration cannot be attempted without addressing the potential societal impacts of such a high degree of automation and data sharing. Additionally, the feasibility of coordinating so many disparate tasks will require a fast, extensible, unifying framework. To that end, we propose FaRO2, a completely reimagined successor to FaRO1, built from the ground up. FaRO2 affords all of the same functionality as its predecessor, serving as a unified biometric API harness that allows for seamless evaluation, deployment, and simple pipeline creation for heterogeneous biometric software. FaRO2 additionally provides a fully declarative capability for defining and coordinating custom machine learning and sensor pipelines, allowing the distribution of processes across otherwise incompatible hardware and networks. FaRO2 ultimately provides a way to quickly configure, hot-swap, and expand large coordinated or federated systems online without interruptions for maintenance. Because much of the data collected in a smart city contains Personally Identifying Information (PII), FaRO2 also provides built-in tools and layers to ensure secure and encrypted streaming, storage, and access of PII data across distributed systems.
- Published
- 2022
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