40 results on '"Mukta Kulkarni"'
Search Results
2. Disability inclusion in Indian workplaces: Mapping the research landscape and exploring new terrains
- Author
-
Devi Vijay, Mukta Kulkarni, K.V. Gopakumar, and Michele Friedner
- Subjects
Disability ,Inclusion ,India ,Business ,HF5001-6182 - Abstract
In this commentary, we reflect upon twenty years of disability research in the Indian workplace and identify possibilities for new conversations and terrains of inquiry. We trace the key frames, theories, and methodological tendencies that demarcate this scholarship. We suggest that researchers can open new terrains of inquiry by situating disability in context, exploring heterogeneous forms of organising and workplace arrangements, and connecting workplace relations and interactions with wider institutional and sociopolitical discourses. We conclude with reflections on disability and inclusion otherwise.
- Published
- 2024
- Full Text
- View/download PDF
3. Titanium Dioxide Nanotube Arrays for Cardiovascular Stent Applications
- Author
-
Ita Junkar, Mukta Kulkarni, Metka Benčina, Janez Kovač, Katjuša Mrak-Poljšak, Katja Lakota, Snežna Sodin-Šemrl, Miran Mozetič, and Aleš Iglič
- Subjects
Chemistry ,QD1-999 - Published
- 2020
- Full Text
- View/download PDF
4. Digital accessibility: Challenges and opportunities
- Author
-
Mukta Kulkarni
- Subjects
Business ,HF5001-6182 - Abstract
This round table is focussed on outlining barriers to digital accessibility, solutions, and possible next steps to ensuring digital accessibility. In setting the context of the round table discussion, the article first outlines what accessibility involves, accessibility standards and guidelines, and spells out barriers to accessibility, including the limitations posed by the institutional context and the technology context. It also discusses the status of digital accessibility in India. The article then reports on a panel discussion in which diverse stakeholders discussed several of the issues outlined above. Keywords: Digital accessibility, Inclusion, Best practices, Barriers to accessibility, Disability, India
- Published
- 2019
- Full Text
- View/download PDF
5. Discursive work within weak field mandate events: The case of a conference on assistive technologies for persons with disabilities
- Author
-
Mukta Kulkarni
- Subjects
Business ,HF5001-6182 - Abstract
The present study outlines discursive work in a weak field mandate event. The case is a conference focussed on assistive technologies that may help persons with disabilities gain better access to educational and employment spaces in India. Findings highlight three mechanisms which underpinned event-specific discursive work – discursive clarity, alignment, and coordination. In outlining such discursive work, the present study indicates how actors, who congregate as a group without high symbolic or resource support from powerful institutional elites, attempt to influence broader processes of institutionalisation. Keywords: Discourse, Field-level events, Disability, Assistive technologies
- Published
- 2018
- Full Text
- View/download PDF
6. Institutional discourses and ascribed disability identities
- Author
-
Mukta Kulkarni, K.V. Gopakumar, and Devi Vijay
- Subjects
Discourse ,Ascribed identity ,Disability ,India ,Business ,HF5001-6182 - Abstract
In the present study we asked: how do institutional discourses, as represented in mass media such as newspapers, confer identities upon a traditionally marginalised collective such as those with a disability? To answer our question, we examined Indian newspaper discourse from 2001 to 2010, the time period between two census counts. We observed that disability identities—that of a welfare recipient, a collective with human rights, a collective that is vulnerable, and that engages in miscreancy—were ascribed through selective highlighting of certain aspects of the collective, thereby socially positioning the collective, and through the associated signalling of institutional subject positions. Present observations indicate that identities of a collective can be governed by institutional discourse, that those “labelled” can themselves reinforce institutionally ascribed identities, and that as institutional discourses confer identities onto the marginalised, they simultaneously also signal who the relatively more powerful institutional actors are.
- Published
- 2017
- Full Text
- View/download PDF
7. Interaction between Dipolar Lipid Headgroups and Charged Nanoparticles Mediated by Water Dipoles and Ions
- Author
-
Aleš Iglič, Nataša Poklar Ulrih, Kristina Eleršič, Šarka Perutkova, Veronika Kralj-Iglič, Mukta Kulkarni, Aljaž Velikonja, Ekaterina Gongadze, and Poornima Budime Santhosh
- Subjects
charged nanoparticles ,lipids ,osmotic pressure ,dipolar zwitterionicheadgroups ,relative permittivity of water ,orientational ordering ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
In this work, a theoretical model describing the interaction between a positivelyor negatively charged nanoparticle and neutral zwitterionic lipid bilayers is presented. It isshown that in the close vicinity of the positively charged nanoparticle, the zwitterionic lipidheadgroups are less extended in the direction perpendicular to the membrane surface, whilein the vicinity of the negatively charged nanoparticle, the headgroups are more extended.This result coincides with the calculated increase in the osmotic pressure between the zwitterionic lipid surface and positively charged nanoparticle and the decrease of osmoticpressure between the zwitterionic lipid surface and the negatively charged nanoparticle.Our theoretical predictions agree well with the experimentally determined fluidity of alipid bilayer membrane in contact with positively or negatively charged nanoparticles. Theprospective significance of the present work is mainly to contribute to better understandingof the interactions of charged nanoparticles with a zwitterionic lipid bilayer, which may beimportant in the efficient design of the lipid/nanoparticle nanostructures (like liposomes withencapsulated nanoparticles), which have diverse biomedical applications, including targetedtherapy (drug delivery) and imaging of cancer cells.
- Published
- 2013
- Full Text
- View/download PDF
8. Don’t ask, don’t tell: Two views on human resource practices for people with disabilities
- Author
-
Mukta Kulkarni and Reimara Valk
- Subjects
People with disabilities ,Human resource practices ,Business ,HF5001-6182 - Abstract
In the present paper we explore how employees with physical disabilities and their human resource managers perceive practices aimed at entry, integration, and development of disabled employees. The results indicate that both sets of respondents want to treat people with disabilities as ‘regular’ employees and take attention away from disability. The results also indicate that employees would like to get additional help, but are afraid to ask. Employers do not offer additional support unless asked, not wanting to highlight the disability given fears of stigmatisation. Given this reluctance from both employees and employers, it is possible that people with disabilities remain an underutilised resource.
- Published
- 2010
- Full Text
- View/download PDF
9. Fluorodeoxyglucose PET/CT and Tc99m-Sestamibi scan, dual tracer imaging in evaluation of osteonecrosis of jaw
- Author
-
Prathamesh Joshi, Mukta Kulkarni, and Hrishikesh Joshi
- Subjects
Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 ,Diseases of the digestive system. Gastroenterology ,RC799-869 - Published
- 2012
- Full Text
- View/download PDF
10. Overqualification, mismatched qualification, and hiring decisions : Perceptions of employers
- Author
-
Mukta Kulkarni, Mark L. Lengnick-Hall, and Patricia G. Martinez
- Published
- 2015
- Full Text
- View/download PDF
11. Strangers at the Bedside: Solidarity-making to address institutionalized infrastructural inequalities
- Author
-
Devi Vijay, Philippe Monin, and Mukta Kulkarni
- Subjects
Organizational Behavior and Human Resource Management ,Management of Technology and Innovation ,Strategy and Management - Abstract
This study explores how heterogeneous actors produce solidarities to address institutionalized infrastructural inequalities. We trace fifteen years over which diverse actors constructed community palliative care infrastructure in Kerala, India. We analyse how actors engaged in solidarity processes of recognizing interdependences, reconfiguring spaces and re-imagining accountability to challenge exclusionary institutions and construct inclusive infrastructure at different scales. We foreground solidarity-making as an indispensable yet under-theorized aspect of institutional research on inequalities. We inform solidarity studies by illustrating how solidarity-making pulsates infrastructures with diverse webs of relations and spatial configurations. Overall, we advance a generative engagement with heterogeneity in institutional analyses and discuss the implications of solidarity-making to address infrastructural inequalities.
- Published
- 2023
12. Mechanical properties of anodic titanium dioxide nanostructures
- Author
-
Matej Daniel, Chandrashekhar V. Rode, Mukta Kulkarni, Josef Sepitka, Metka Benčina, Patrik Schmuki, Aleš Iglič, Suresh Gokhale, Niharika Rawat, Ita Junkar, and Anca Mazare
- Subjects
Nanostructure ,Materials science ,Polymers and Plastics ,Scanning electron microscope ,Metals and Alloys ,symbols.namesake ,chemistry.chemical_compound ,chemistry ,Titanium dioxide ,Vickers hardness test ,symbols ,Composite material ,Raman spectroscopy ,Spectroscopy ,Elastic modulus ,FOIL method - Abstract
Highly ordered and uniform titanium dioxide (TiO2) nanotubes (NTs) with different morphologies (15 nm, 50 nm and 100 nm in diameter) were prepared by the electrochemical anodization of Ti substrates. The TiO2 NTs’ surface properties were characterized by X-ray diffraction (XRD) spectroscopy, Raman spectroscopy, scanning electron microscopy (SEM) and atomic force microscopy (AFM). The elastic modulus (E) and the Vickers hardness (HV) of the Ti foil and of the different-morphology TiO2 NTs were evaluated with the nano-indentation technique. E and HV increase with the decreasing length/diameter of the NTs, meaning that NTs with smaller diameters are more resistant to mechanical wear. The elastic modulus of the TiO2 NTs with 15-nm and 50-nm diameters is similar to that of the human bone.
- Published
- 2021
13. Titanium Dioxide Nanotube Arrays for Cardiovascular Stent Applications
- Author
-
Katja Lakota, Mukta Kulkarni, Miran Mozetič, Katjuša Mrak-Poljšak, Janez Kovač, Aleš Iglič, Metka Benčina, S. Sodin-Šemrl, and Ita Junkar
- Subjects
Neointimal hyperplasia ,Materials science ,General Chemical Engineering ,medicine.medical_treatment ,chemistry.chemical_element ,Stent ,General Chemistry ,medicine.disease ,Article ,Titanium oxide ,Contact angle ,chemistry.chemical_compound ,Chemistry ,chemistry ,Restenosis ,Titanium dioxide ,medicine ,Cell adhesion ,QD1-999 ,Titanium ,Biomedical engineering - Abstract
Efficient stent implantation among others depends on avoiding the aggregation of platelets in the blood vessels and appropriate proliferation of endothelial cells and controlled proliferation of smooth muscle cells, which reduces the development of pathology, such as neointimal hyperplasia, thrombosis, and restenosis. The current article provides an elegant solution for prevention of platelet and smooth muscle cell adhesion and activation on stent surfaces while obtaining surface conditions to support the growth of human coronary artery endothelial cells. This was achieved by surface nanostructuring and chemical activation of the surface. Specific nanotopographies of titanium were obtained by electrochemical anodization, while appropriate chemical properties were attained by treatment of titanium oxide nanotubes by highly reactive oxygen plasma. Surface properties were studied by scanning electron microscopy, atomic force microscopy, and X-ray photoelectron spectroscopy. Wettability was evaluated by measuring the water contact angle. The influence of nanostructured morphology and plasma modification on in vitro biological response with human coronary artery endothelia and smooth muscle cells as well as whole blood was studied. Our results show that a combination of nanostructuring and plasma modification of the surfaces is an effective way to achieve desired biological responses necessary for implantable materials such as stents.
- Published
- 2020
14. The Role of Moral Anger in Social Change Efforts
- Author
-
Mukta Kulkarni
- Subjects
Organizational Behavior and Human Resource Management ,Management of Technology and Innovation ,Strategy and Management - Abstract
Drawing upon the functional account of emotions—the view that emotions can facilitate adaptive responses—I analyze how Javed Abidi harnessed moral anger to promote inclusion of persons with disabilities in India. The data comprise articles obtained from digital archives covering the period from 1993, when Abidi began his work, to 2018, when he passed away. Findings suggest that harnessing moral anger can facilitate social change through two mechanisms: disciplined collectivization wherein aggregated stakeholders can appraise injustice; and enabling collective enactment wherein they can redress injustice by choosing if, when, and how to effect change. Despite ongoing propriety breaches, moral anger can remain functional when stakeholders can balance their immersion across initiatives and can perceive change as a beneficial proxy for or an expansion of existing values. As such, the study contributes by drawing attention to the theoretical significance that a functional account has for expanding the literature on moral anger as it applies within the context of social change.
- Published
- 2023
15. AuntMinnie fluorodeoxyglucose positron emission tomography-computed tomography leads to diagnosis of immunoglobulin G4-related disease
- Author
-
PrathameshVijay Joshi, AnandMaruti Nikalje, Mukta Kulkarni, and NehaDeepak Borde
- Subjects
Radiology, Nuclear Medicine and imaging - Published
- 2022
16. How effective are disability sensitization workshops?
- Author
-
Shivani Patel, K.V. Gopakumar, and Mukta Kulkarni
- Subjects
Organizational Behavior and Human Resource Management ,Medical education ,business.industry ,05 social sciences ,050209 industrial relations ,Psychological intervention ,Organizational culture ,medicine.anatomical_structure ,Turnover ,0502 economics and business ,Industrial relations ,medicine ,Isolation (psychology) ,Human resources ,business ,Psychology ,Social psychology ,050203 business & management ,Sensitization ,Organizational level - Abstract
PurposeOrganizations are increasingly investing in disability-specific sensitization workshops. Yet, there is limited understanding about their hoped outcomes, that is, increased knowledge about disability-related issues and behavioral changes with respect to those with a disability. The purpose of this paper is to examine the effectiveness and boundaries of disability-specific sensitization training in organizations.Design/methodology/approachThis is an interview-based study where 33 employees from five industries across India were interviewed over the span of a year.FindingsThe findings suggest that sensitization workshops are successful with regard to awareness generation. Paradoxically, the same awareness also reinforced group boundaries through “othering.” Further, workshops resonated more so with individuals who already had some prior experience with disability, implying that voluntary sensitization is likely attracting those who have the least need of such sensitization. The findings also suggest that non-mandated interventions may not necessarily influence organizational level outcomes, especially if workshops are conducted in isolation from a broader organizational culture of inclusion.Originality/valueThe present study helps outline effects of sensitization training initiatives and enhances our understanding about how negative attitudes toward persons with a disability can be overcome. The study also indicates how such training initiatives may inadvertently lead to “othering.” Finally, this study offers suggestions to human resource managers for designing impactful disability sensitization workshops.
- Published
- 2018
17. Institutional discourses and ascribed disability identities
- Author
-
Devi Vijay, K.V. Gopakumar, and Mukta Kulkarni
- Subjects
Economics and Econometrics ,media_common.quotation_subject ,Subject (philosophy) ,India ,Ascribed identity ,Discourse ,lcsh:Business ,Newspaper ,03 medical and health sciences ,030502 gerontology ,0502 economics and business ,Sociology ,Socioeconomics ,Mass media ,media_common ,Disability ,Human rights ,business.industry ,05 social sciences ,Gender studies ,General Medicine ,General Business, Management and Accounting ,Welfare recipient ,0305 other medical science ,business ,lcsh:HF5001-6182 ,050203 business & management ,Period (music) - Abstract
In the present study we asked: how do institutional discourses, as represented in mass media such as newspapers, confer identities upon a traditionally marginalised collective such as those with a disability? To answer our question, we examined Indian newspaper discourse from 2001 to 2010, the time period between two census counts. We observed that disability identities—that of a welfare recipient, a collective with human rights, a collective that is vulnerable, and that engages in miscreancy—were ascribed through selective highlighting of certain aspects of the collective, thereby socially positioning the collective, and through the associated signalling of institutional subject positions. Present observations indicate that identities of a collective can be governed by institutional discourse, that those “labelled” can themselves reinforce institutionally ascribed identities, and that as institutional discourses confer identities onto the marginalised, they simultaneously also signal who the relatively more powerful institutional actors are.
- Published
- 2017
18. Disability, Gender and Race: Does Educational Attainment Reduce Earning Disparity for All or Just Some?
- Author
-
Mukta Kulkarni, David C. Baldridge, Beatrix Eugster, and Richard Dirmyer
- Subjects
Race (biology) ,lcsh:Personnel management. Employment management ,lcsh:HF5549-5549.5 ,lcsh:Industrial psychology ,Demographic economics ,Psychology ,Educational attainment ,lcsh:HF5548.7-5548.85 - Published
- 2019
19. Protein interactions with layers of TiO2 nanotube and nanopore arrays: Morphology and surface charge influence
- Author
-
Mukta Kulkarni, Anca Mazare, Slavko Kralj, Ekaterina Gongadze, Patrik Schmuki, Jung Park, Manuela S. Killian, Aleš Iglič, and Klaus von der Mark
- Subjects
Nanotube ,Materials science ,Biomedical Engineering ,Charge density ,Nanotechnology ,02 engineering and technology ,General Medicine ,Adhesion ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Biochemistry ,Electric charge ,0104 chemical sciences ,Biomaterials ,Nanopore ,Surface area ,Chemical engineering ,Surface charge ,0210 nano-technology ,Molecular Biology ,Biotechnology ,Protein adsorption - Abstract
In the present work we investigate the key factors involved in the interaction of small-sized charged proteins with TiO 2 nanostructures, i.e. albumin (negatively charged), histone (positively charged). We examine anodic nanotubes with specific morphology (simultaneous control over diameter and length, e.g. diameter – 15, 50 or 100 nm, length – 250 nm up to 10 μm) and nanopores. The nanostructures surface area has a direct influence on the amount of bound protein, nonetheless the protein physical properties as electric charge and size (in relation to nanotopography and biomaterial’s electric charge) are crucial too. The highest quantity of adsorbed protein is registered for histone, for 100 nm diameter nanotubes (10 μm length) while higher values are registered for 15 nm diameter nanotubes when normalizing protein adsorption to nanostructures’ surface unit area (evaluated from dye desorption measurements) – consistent with theoretical considerations. The proteins presence on the nanostructures is evaluated by XPS and ToF-SIMS; additionally, we qualitatively assess their presence along the nanostructures length by ToF-SIMS depth profiles, with decreasing concentration towards the bottom. Statement of Significance Surface nanostructuring of titanium biomedical devices with TiO 2 nanotubes was shown to significantly influence the adhesion, proliferation and differentiation of mesenchymal stem cells (and other cells too). A high level of control over the nanoscale topography and over the surface area of such 1D nanostructures enables a direct influence on protein adhesion. Herein, we investigate and show how the nanostructure morphology (nanotube diameter and length) influences the interactions with small-sized charged proteins, using as model proteins bovine serum albumin (negatively charged) and histone (positively charged). We show that the protein charge strongly influences their adhesion to the TiO 2 nanostructures. Protein adhesion is quantified by ELISA measurements and determination of the nanostructures’ total surface area. We use a quantitative surface charge model to describe charge interactions and obtain an increased magnitude of the surface charge density at the top edges of the nanotubes. In addition, we track the proteins presence on and inside the nanostructures. We believe that these aspects are crucial for applications where the incorporation of active molecules such as proteins, drugs, growth factors, etc., into nanotubes is desired.
- Published
- 2016
20. Influence Of Anodization Parameters On Morphology Of TiO2 Nanostructured Surfaces
- Author
-
Anca Mazare, Aleš Iglič, Mukta Kulkarni, and Patrik Schmuki
- Subjects
Materials science ,Morphology (linguistics) ,Anodizing ,General Materials Science ,Nanotechnology ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,0210 nano-technology ,Smart material ,01 natural sciences ,Electrochemical anodization ,0104 chemical sciences - Published
- 2016
21. 'Face mask sign' on Tc-99m methylene diphosphonate bone scan
- Author
-
Prathamesh Joshi, Kritik Kumar, and Mukta Kulkarni
- Subjects
Prostate biopsy ,medicine.diagnostic_test ,business.industry ,Chronic sinusitis ,Prostate carcinoma ,medicine.disease ,medicine.anatomical_structure ,Prostate ,otorhinolaryngologic diseases ,Medicine ,Adenocarcinoma ,business ,Nuclear medicine ,Sinusitis ,Nose ,Sinus (anatomy) - Abstract
Although bone scan is a sensitive imaging modality, it is nonspecific, and there are multiple potential causes of abnormal isotope uptake that can mimic metastatic disease. A 67-year-old male, a known case of prostate carcinoma, underwent bone scan for skeletal evaluation. His prostate biopsy had revealed adenocarcinoma of the prostate. His serum prostate-specific antigen level was 11.8 ng/ml. The scan showed increased tracer uptake in bilateral maxillary sinuses mimicking shape of the face mask. To characterize the abnormal tracer uptake in the bilateral maxillary sinuses and rule out the metastatic lesion, single-photon emission computed tomography–computed tomography (SPECT-CT) correlation was obtained. The SPECT-CT revealed mucosal thickening obliterating sinus space in the bilateral maxillary sinuses, suggesting the uptake secondary to maxillary sinusitis. On questioning, the patient admitted of having chronic history of pain along the sides of the nose and yellowish nasal mucus discharge. We concluded the uptake to be result of the bilateral maxillary sinusitis. We propose that such uptake pattern can be designated as 'face mask sign' on bone scan.
- Published
- 2020
22. Overqualification, mismatched qualification, and hiring decisions
- Author
-
Mark L. Lengnick-Hall, Mukta Kulkarni, and Patricia G. Martinez
- Subjects
Typology ,Organizational Behavior and Human Resource Management ,Actuarial science ,business.industry ,media_common.quotation_subject ,Qualitative interviews ,Public sector ,Overqualification ,Work experience ,Underemployment ,Perception ,Marketing ,Human resources ,business ,Applied Psychology ,media_common - Abstract
Purpose – The purpose of this paper is to examine how employers define overqualification and mismatched qualification and whether they are willing to hire applicants whose educational and work experience credentials do not match job requirements. Design/methodology/approach – This paper draws from qualitative interview data from 24 hiring managers across a wide range of US public sector and private industries. Data were analyzed and coded to identify themes related to managers’ perceptions of overqualification, matched, and mismatched qualification, and how these were related to selection decisions. A typology is proposed for categorizing applicant qualification levels and their potential human resource outcomes such as hiring decisions. Findings – Hiring managers report that they are willing to interview and hire individuals whose education or experience exceed a job’s requirements as well as applicants with less than required education, but only if they possess sufficient compensatory experience. Research limitations/implications – Findings may not apply to industries where minimum educational levels are essential or to small organizations with few opportunities for career advancement. Social implications – Given current unemployment and underemployment levels, the findings can inform the job search strategies of job seekers. Overqualified applicants should not refrain from applying to job openings, particularly in organizations with opportunities for advancement and where education is considered an asset. Additionally, applicants should reveal their motivations for pursing positions that are intentional mismatches. Originality/value – In contrast to previous studies conducted during periods of lower unemployment and underemployment, these data include managers’ perceptions of overqualification in a recession and post-recession job market context and thus are especially relevant to today’s employment context. The proposed typology distinguishes between categorizations of qualified, overqualified, and underqualified, and helps refine studies aimed at selection decisions.
- Published
- 2015
23. Overqualified? A conceptual model of managers’ perceptions of overqualification in selection decisions
- Author
-
Mukta Kulkarni, Patricia G. Martinez, and Mark L. Lengnick-Hall
- Subjects
Organizational Behavior and Human Resource Management ,business.industry ,media_common.quotation_subject ,Applied psychology ,Cognition ,Overqualification ,Underemployment ,Categorization ,Social cognition ,Conceptual model ,Job satisfaction ,Human resources ,business ,Psychology ,Social psychology ,Applied Psychology ,media_common - Abstract
Purpose – The purpose of this paper is to present a conceptual model for conducting research on how human resource and hiring managers form impressions of overqualified individuals and how these impressions affect their treatment of overqualified individuals during selection decisions. Design/methodology/approach – Given the central role of psychological processes within the proposed model, this conceptual paper builds on a social cognition approach. Findings – The proposed model consists of seven primary factors that can help propel research that is dynamic and contextually driven: attributes of the overqualified individual; job attributes; observers’ cognitive overqualification schemas; observers’ attitudes; observers’ categorization processes; the organizational context; and individual factors, all of which influence the observers’ treatment of overqualified individuals. Originality/value – Most research has focussed on individual-level outcomes of overqualification such as job satisfaction, turnover intentions, and physical and psychological health, while overlooking how organizational decision makers perceive overqualification and how this subsequently affects the likelihood of individuals being selected for an interview. Given the global growth in the number of overqualified workers, understanding antecedents and correlates of overqualification and how these affect organizational selection decisions is a pressing need. The proposed model outlines several factors that can help us better understand the phenomenon of overqualification.
- Published
- 2014
24. Fabrication of TiO2 nanotubes for bioapplications
- Author
-
Mukta Kulkarni, Katjuša Mrak-Poljšak, and Ajda Flašker
- Subjects
Polymers and Plastics ,Metals and Alloys - Published
- 2015
25. Interaction between Dipolar Lipid Headgroups and Charged Nanoparticles Mediated by Water Dipoles and Ions
- Author
-
Nataša Poklar Ulrih, Mukta Kulkarni, Ekaterina Gongadze, Poornima Budime Santhosh, Kristina Eleršič, Veronika Kralj-Iglič, Aleš Iglič, Šárka Perutková, and Aljaž Velikonja
- Subjects
Membrane Fluidity ,Lipid Bilayers ,Static Electricity ,dipolar zwitterionicheadgroups ,Nanoparticle ,charged nanoparticles ,lipids ,osmotic pressure ,relative permittivity of water ,orientational ordering ,biološke membrane ,Article ,Catalysis ,Ion ,lcsh:Chemistry ,Quantitative Biology::Subcellular Processes ,Inorganic Chemistry ,udc:577.352:576.314 ,biofizika membrane ,dipolar zwitterionic headgroups ,Osmotic pressure ,Organic chemistry ,lipidi ,Lipid bilayer phase behavior ,Physical and Theoretical Chemistry ,Membrane surface ,Lipid bilayer ,lcsh:QH301-705.5 ,Molecular Biology ,Spectroscopy ,Ions ,nanodelci ,Physics::Biological Physics ,Chemistry ,Organic Chemistry ,Water ,General Medicine ,Models, Theoretical ,Computer Science Applications ,Condensed Matter::Soft Condensed Matter ,Dipole ,lcsh:Biology (General) ,lcsh:QD1-999 ,Chemical physics ,elektrostatske interakcije ,Nanoparticles ,lipids (amino acids, peptides, and proteins) - Abstract
In this work, a theoretical model describing the interaction between a positively or negatively charged nanoparticle and neutral zwitterionic lipid bilayers is presented. It is shown that in the close vicinity of the positively charged nanoparticle, the zwitterionic lipid headgroups are less extended in the direction perpendicular to the membrane surface, while in the vicinity of the negatively charged nanoparticle, the headgroups are more extended. This result coincides with the calculated increase in the osmotic pressure between the zwitterionic lipid surface and positively charged nanoparticle and the decrease of osmotic pressure between the zwitterionic lipid surface and the negatively charged nanoparticle. Our theoretical predictions agree well with the experimentally determined fluidity of a lipid bilayer membrane in contact with positively or negatively charged nanoparticles. The prospective significance of the present work is mainly to contribute to better understanding of the interactions of charged nanoparticles with a zwitterionic lipid bilayer, which may be important in the efficient design of the lipid/nanoparticle nanostructures (like liposomes with encapsulated nanoparticles), which have diverse biomedical applications, including targeted therapy (drug delivery) and imaging of cancer cells.
- Published
- 2013
26. Social influence and job choice decisions
- Author
-
Siddharth Nithyanand and Mukta Kulkarni
- Subjects
Social comparison theory ,Organizational Behavior and Human Resource Management ,Job shadow ,ComputingMilieux_THECOMPUTINGPROFESSION ,Job performance ,Industrial relations ,Job analysis ,Job design ,Job satisfaction ,Job attitude ,Psychology ,Social psychology ,Social influence - Abstract
PurposePast research has largely portrayed job choice as a relatively rational and goal‐directed behavior where applicants make decisions contingent on organizational recruitment activities, or evaluations of job and organizational attributes. Research now informs us that job choice decisions may also be based on social comparisons and social influence. The purpose of this paper is to add to this body of knowledge by examining reasons why social influence is a key factor in job choice decisions of relatively young job seekers.Design/methodology/approachThe study is based on in‐depth interview data from graduating seniors at an elite business school in India.FindingsRespondents did not see themselves as acting based on social influence as much as they perceived others around them to be. Reasons they noted for others’ socially influenced job choice decisions were: peers and seniors are seen as more accessible and trustworthy than organizations; organizations do not share all and/or objective data, driving job seekers to other sources; job seekers are clueless and hence follow a “smart” herd; and job seekers make decisions for social status signaling. Respondents pointed to socially influenced job choices as being rational behaviors under certain conditions.Research limitations/implicationsGeneralizability of findings may be limited to young job seekers or to the Indian context, and the authors encourage replication. The authors also acknowledge the importance of individual difference variables in job choice decisions, a factor not considered in the present research.Practical implicationsGiven that job seekers rally around others’ notion of an attractive job or an organization, the paper outlines several implications for managerial practice.Originality/valueThis study, in a yet unexamined cultural context, points to the simultaneous and combined importance of normative and informational social determinants of job choice, bias blind spots in one's own job choice perceptions and decisions, gender specific socialization influences on job choices, and the notion of job fit in terms of fitment with expectations of important reference groups.
- Published
- 2012
27. Wettability Switch of Anodic Titanium Dioxide Nanotubes with Various Diameters
- Author
-
Harinarayanan Puliyalil, Aleš Iglič, Mukta Kulkarni, and Ita Junkar
- Subjects
Materials science ,Anodizing ,Biophysics ,Nanotechnology ,02 engineering and technology ,Electrolyte ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Anode ,Contact angle ,chemistry.chemical_compound ,Hydrofluoric acid ,chemistry ,Chemical engineering ,Titanium dioxide ,Wetting ,0210 nano-technology ,Ethylene glycol - Abstract
Surface topography and physicochemical properties such as adhesion, cohesion and wettability is presumed to alter/facilitate the protein binding, cell adhesion and proliferation, thereby reducing post-operative complications with increased lifespan of biomedical implants.1 Current study examines the ageing behaviour of titanium dioxide (TiO2) nanotubes with various diameters and their switch in wettability by gaseous plasma treatment.Self-organized TiO2 nanotube layers were fabricated according to the electrochemical anodization method published earlier.2 The ethylene glycol based electrolytes were used for growing the nanostructures which contains specific amount of water and specific concentration of hydrofluoric acid. Anodization parameters such as applied voltage as well as experimental time were optimized to get desired diameters (15nm, 50nm and 100nm) of TiO2 nanotubes. As-anodized surfaces are hydrophilic and tend to age with time to more hydrophobic. Water contact angle measurements were performed during seven weeks period to study ageing behaviour as well as switch in wettability after gaseous plasma treatment. All the contact angle measurements were performed with demineralized water. The contact angle was measured by fitting the water drop on the surface. Surface wettability indeed switched after plasma treatment as the surface became hydrophilic. Changes in wettability after ageing were explained by organic contamination from ambient atmosphere, while hydrophilic character was obtained after plasma treatment due to removal of these contaminants. Moreover storing the samples in sealed container also influenced on their ageing profile.This current work provides solution and guidelines by which switch in wettability of TiO2 nanotubes can be achieved and can be employed in medical applications where hydrophilic character is desired for specific application, such as orthopedic implants.References:1. M. Ventre, F. Causa, P.A. Netti, J. R. Soc. Interface 9 (2012) 2017.2. Kulkarni M. et al. Int. J. Nanomed. 10 (2015)1359.
- Published
- 2016
- Full Text
- View/download PDF
28. Don’t ask, don’t tell: Two views on human resource practices for people with disabilities
- Author
-
Reimara Valk and Mukta Kulkarni
- Subjects
Economics and Econometrics ,People with disabilities ,Actuarial science ,business.industry ,Business, Management and Accounting(all) ,Human resource practices ,lcsh:Business ,Public relations ,General Business, Management and Accounting ,Resource (project management) ,Ask price ,ComputingMilieux_COMPUTERSANDSOCIETY ,lcsh:HF5001-6182 ,Human resources ,business ,Psychology ,ComputingMilieux_MISCELLANEOUS - Abstract
In the present paper we explore how employees with physical disabilities and their human resource managers perceive practices aimed at entry, integration, and development of disabled employees. The results indicate that both sets of respondents want to treat people with disabilities as ‘regular’ employees and take attention away from disability. The results also indicate that employees would like to get additional help, but are afraid to ask. Employers do not offer additional support unless asked, not wanting to highlight the disability given fears of stigmatisation. Given this reluctance from both employees and employers, it is possible that people with disabilities remain an underutilised resource.
- Published
- 2010
29. The role of leadership in emergent, self-organization
- Author
-
Mukta Kulkarni, Tammy E. Beck, Deandra Villarreal Travis, Donde Ashmos Plowman, LaKami T. Baker, and Stephanie T. Solansky
- Subjects
Organizational Behavior and Human Resource Management ,Knowledge management ,Sociology and Political Science ,business.industry ,Control (management) ,Novelty ,Public relations ,Shared leadership ,Empirical research ,Transactional leadership ,Leadership style ,Sociology ,Business and International Management ,Set (psychology) ,business ,Applied Psychology ,Qualitative research - Abstract
As complex systems, organizations exist far from equilibrium where the ongoing interaction of system components leads to emergent and self-organizing behavior. What, then, is the role of leadership in systems where change often emerges in unexpected ways? In this paper, we build on the work of Marion and Uhl-Bien who suggest that in complex systems leaders enable rather than control the future. While traditional views of leadership focus on the leader's responsibility for determining and directing the future through heavy reliance on control mechanisms, we offer empirical support for a different view of leadership based on a complexity perspective of organizations. Our findings show that as enablers, leaders disrupt existing patterns of behavior, encourage novelty, and make sense of emerging events for others. The results of our qualitative study include a set of research propositions as well as a discussion of the implications for managers and researchers.
- Published
- 2007
30. Radical Change Accidentally: The Emergence and Amplification of Small Change
- Author
-
Stephanie T. Solansky, Deandra Villarreal Travis, Donde Ashmos Plowman, Tammy E. Beck, LaKami T. Baker, and Mukta Kulkarni
- Subjects
Management of Technology and Innovation ,Strategy and Management ,Organizational change ,Political economy ,Religious organization ,Sociology ,Theory of change ,Business and International Management ,General Business, Management and Accounting ,Management - Abstract
A decision to offer breakfast to homeless people led to radical change in a church and its environment. Existing theories of change do not fully explain observations from our qualitative study; however, complexity theory constructs suggest how and why such change emerged. We offer four key findings. First, the radical change was unintended, emergent, and slow. Second, destabilizing conditions helped small changes to emerge and become radical. Third, subsequent actions amplified an initial small change and, though not intended to do so, promoted radical change. Finally, the dynamic interaction of amplifying actions, contextual conditions, and small changes led to continuous radical change.
- Published
- 2007
31. Influence of various sterilization procedures on TiO2 nanotubes used for biomedical devices
- Author
-
Ita Junkar, Anca Mazare, Miran Mozetič, Damjana Drobne, Petr Humpolíček, Patrik Schmuki, Ajda Flašker, Aleš Iglič, Barbara Drasler, Matic Resnik, Mukta Kulkarni, and Neža Rugelj
- Subjects
Nanotube ,Materials science ,Plasma Gases ,Cell Survival ,Surface Properties ,Ultraviolet Rays ,Biophysics ,chemistry.chemical_element ,Nanotechnology ,Biocompatible Materials ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,Autoclave ,Cell Line ,Materials Testing ,Electrochemistry ,Humans ,Plasma sterilization ,Physical and Theoretical Chemistry ,Titanium ,Nanotubes ,Osteoblasts ,Gaseous oxygen ,Sterilization ,General Medicine ,Equipment Design ,Hydrogen Peroxide ,Sterilization (microbiology) ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Oxygen ,Key factors ,chemistry ,Treatment procedure ,0210 nano-technology - Abstract
Sterilization is the final surface treatment procedure of all implantable devices and is one of the key factors which have to be considered before implementation. Since different sterilization procedures for all implantable devices influence mechanical properties as well as biological response, the influence of different sterilization techniques on titanium nanotubes was studied. Commonly used sterilization techniques such as autoclaving, ultra-violet light sterilization, hydrogen peroxide plasma sterilization as well as the not so frequently used gaseous oxygen plasma sterilization were used. Three different nanotube diameters; 15 nm, 50 nm and 100 nm were employed to study the effects of various sterilization techniques. It was observed that autoclave sterilization resulted in destruction of nanotubular features on all three studied nanotube diameters, while UV-light and both kinds of plasma sterilization did not cause any significant morphological changes on the surfaces. Differences between the sterilization techniques employed influenced cytocompatibility, especially in the case of nanotubes with 100 nm diameter.
- Published
- 2015
32. Wettability studies of topologically distinct titanium surfaces
- Author
-
Yogita Patil-Sen, Martina Lorenzetti, Chandrashekhar Vishwanath Kulkarni, Ita Junkar, Mukta Kulkarni, Aleš Iglič, and Patil-Sen, Yogita
- Subjects
Nanostructure ,Materials science ,Surface Properties ,F100 ,Evaporation ,chemistry.chemical_element ,Nanotechnology ,Surface finish ,Microscopy, Atomic Force ,Contact angle ,chemistry.chemical_compound ,Colloid and Surface Chemistry ,Materials Testing ,Physical and Theoretical Chemistry ,Titanium ,technology, industry, and agriculture ,Surfaces and Interfaces ,General Medicine ,Nanostructures ,chemistry ,Chemical engineering ,Titanium dioxide ,Microscopy, Electron, Scanning ,Wettability ,Wetting ,Contact area ,Hydrophobic and Hydrophilic Interactions ,Biotechnology - Abstract
Biomedical implants made of titanium-based materials are expected to have certain essential features including high bone-to-implant contact and optimum osteointegration, which are often influenced by the surface topography and physicochemical properties of titanium surfaces. The surface structure in the nanoscale regime is presumed to alter/facilitate the protein binding, cell adhesion and proliferation, thereby reducing post-operative complications with increased lifespan of biomedical implants. The novelty of our TiO2 nanostructures lies mainly in the high level control over their morphology and roughness by mere compositional change and optimisation of the experimental parameters. The present work focuses on the wetting behaviour of various nanostructured titanium surfaces towards water. Kinetics of contact area of water droplet on macroscopically flat, nanoporous and nanotubular titanium surface topologies was monitored under similar evaporation conditions. The contact area of the water droplet on hydrophobic titanium planar surface (foil) was found to decrease during evaporation, whereas the contact area of the droplet on hydrophobic nanorough titanium surfaces practically remained unaffected until the complete evaporation. This demonstrates that the surface morphology and roughness at the nanoscale level substantially affect the titanium dioxide surface–water droplet interaction, opposing to previous observations for microscale structured surfaces. The difference in surface topographic nanofeatures of nanostructured titanium surfaces could be correlated not only with the time-dependency of the contact area, but also with time-dependency of the contact angle and electrochemical properties of these surfaces.
- Published
- 2015
33. Binding of plasma proteins to titanium dioxide nanotubes with different diameters
- Author
-
Aleš Iglič, Andrej Artenjak, Anca Mazare, Katjuša Mrak-Poljšak, Slavko Kralj, Ajda Flašker, Patrik Schmuki, Veronika Kralj-Iglič, Maruša Lokar, Aljaž Velikonja, Saša Čučnik, Mukta Kulkarni, and Snezna Sodin-Semrl
- Subjects
Materials science ,Biocompatibility ,Biophysics ,Pharmaceutical Science ,chemistry.chemical_element ,Bioengineering ,Nanotechnology ,protein binding ,Corrosion ,Biomaterials ,immunoglobulin G ,chemistry.chemical_compound ,International Journal of Nanomedicine ,Materials Testing ,Drug Discovery ,Zeta potential ,Bicinchoninic acid assay ,Particle Size ,Original Research ,Titanium ,Nanotubes ,β2-glycoprotein I ,Organic Chemistry ,Titanium alloy ,serum amyloid A ,Blood Proteins ,General Medicine ,respiratory system ,Blood proteins ,histone IIA ,chemistry ,Chemical engineering ,Titanium dioxide - Abstract
Mukta Kulkarni,1,* Ajda Flašker,1,* Maruša Lokar,1 Katjuša Mrak-Poljšak,2 Anca Mazare,3 Andrej Artenjak,4 Saša ÄuÄnik,2 Slavko Kralj,5 Aljaž Velikonja,1 Patrik Schmuki,3 Veronika Kralj-IgliÄ,6 Snezna Sodin-Semrl,2,7 Aleš IgliÄ11Laboratory of Biophysics, Faculty of Electrical Engineering, University of Ljubljana, Ljubljana, Slovenia; 2Department of Rheumatology, University Medical Centre Ljubljana,Ljubljana, Slovenia; 3Department of Materials Science and Engineering, University of Erlangen Nuremberg, Erlangen, Germany; 4Sandoz Biopharmaceuticals Mengeš, Lek Pharmaceuticals dd, Menges, Slovenia; 5Department for Materials Synthesis, Institute Jožef Stefan (IJS), Ljubljana, Slovenia; 6Faculty of Health Studies, University of Ljubljana, Ljubljana, Slovenia; 7Faculty of Mathematics, Natural Science and Information Technology, University of Primorska, Koper, Slovenia *These authors contributed equally to this workAbstract: Titanium and titanium alloys are considered to be one of the most applicable materials in medical devices because of their suitable properties, most importantly high corrosion resistance and the specific combination of strength with biocompatibility. In order to improve the biocompatibility of titanium surfaces, the current report initially focuses on specifying the topography of titanium dioxide (TiO2) nanotubes (NTs) by electrochemical anodization. The zeta potential (ζ-potential) of NTs showed a negative value and confirmed the agreement between the measured and theoretically predicted dependence of ζ-potential on salt concentration, whereby the absolute value of ζ-potential diminished with increasing salt concentrations. We investigated binding of various plasma proteins with different sizes and charges using the bicinchoninic acid assay and immunofluorescence microscopy. Results showed effective and comparatively higher protein binding to NTs with 100 nm diameters (compared to 50 or 15nm). We also showed a dose-dependent effect of serum amyloid A protein binding to NTs. These results and theoretical calculations of total available surface area for binding of proteins indicate that the largest surface area (also considering the NT lengths) is available for 100 nm NTs, with decreasing surface area for 50 and 15 nm NTs. These current investigations will have an impact on increasing the binding ability of biomedical devices in the body leading to increased durability of biomedical devices. Keywords: protein binding, serum amyloid A, β2-glycoprotein I, immunoglobulin G, histone IIA
- Published
- 2015
34. Biomolecules Altering the Lipid Molecular Shape in Model Non-Lamellar Membranes
- Author
-
Mukta Kulkarni, Aleš Iglič, Yogita Patil-Sen, and Chandrashekhar Vishwanath Kulkarni
- Subjects
chemistry.chemical_classification ,Liposome ,Chemistry ,Biomolecule ,Biophysics ,Biological membrane ,Nanotechnology ,Micelle ,Molecular geometry ,Membrane ,Lamellar structure ,lipids (amino acids, peptides, and proteins) ,Intracellular - Abstract
Intracellular membranes exhibit complex, highly dynamic and non-lamellar morphologies.1 Structural resemblance of such membranes with bicontinuous cubic and hexagonal lipid phases has been recognised in past two decades.2 However, principles behind their dynamic organization and structural roles in cellular processes still remain elusive. Model membrane systems like liposomes, planar lipid bilayers and micelles have been largely used to interact various biomolecules to determine structures and functions of biomembrane systems.
- Published
- 2015
- Full Text
- View/download PDF
35. Extraosseous accumulation of bone scan tracer 99mTc-methylene diphosphonate in a phlebolith
- Author
-
Archi Agrawal, Anand Zade, Nilendu Purandare, Venkatesh Rangarajan, Mukta Kulkarni, and Sneha Shah
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Methylene diphosphonate ,Computed tomography ,Case Report ,Bone scan ,Bone scans ,phlebolith ,Phlebolith ,Bone scintigraphy ,Photon emission ,SPECT-CT ,medicine ,Radiology, Nuclear Medicine and imaging ,Radiology ,business ,Nuclear medicine ,extraosseous uptake ,99mTc-methylene diphosphonate ,99mTc-Methylene Diphosphonate - Abstract
Uptake in non-osseous, non-urologic tissues is occasionally found in the performance of bone scintigraphy. These uptakes reflect an atypical interaction between the radiopharmaceutical and the patient. Knowledge of the rare extraskeletal uptakes and their clinical relevance helps in better interpretation of bone scans. We report an unusual occurrence of extraosseous accumulation of 99m Tc-methylene diphosphonate in a phlebolith in bone scan, confirmed with the aid of photon emission computed tomography and computed tomography.
- Published
- 2012
36. Experimental data and theoretical modelling on the electrokinetics of porous TiO2-coatings for body implants
- Author
-
Martina, Lorenzetti, primary, Mukta, Kulkarni, additional, Ekaterina, Gongadze, additional, and Ale�, Iglic, additional
- Published
- 2016
- Full Text
- View/download PDF
37. Titanium nanostructures for biomedical applications
- Author
-
Anca Mazare, Ingrid Milošev, Miran Mozetič, Patrik Schmuki, Šárka Perutková, Mukta Kulkarni, Aleš Iglič, Veronika Kralj-Iglič, and Ekaterina Gongadze
- Subjects
Materials science ,Biocompatibility ,Surface Properties ,Technische Fakultät ,Biomedical Technology ,chemistry.chemical_element ,Biocompatible Materials ,Bioengineering ,Nanotechnology ,Osseointegration ,chemistry.chemical_compound ,Cell Adhesion ,Animals ,Humans ,General Materials Science ,Nanotopography ,Electrical and Electronic Engineering ,Cell adhesion ,Titanium ,Nanotubes ,Orthopedic Equipment ,Mechanical Engineering ,Titanium alloy ,Prostheses and Implants ,General Chemistry ,Adhesion ,Anti-Bacterial Agents ,chemistry ,Mechanics of Materials ,Titanium dioxide ,ddc:600 - Abstract
Titanium and titanium alloys exhibit a unique combination of strength and biocompatibility, which enables their use in medical applications and accounts for their extensive use as implant materials in the last 50 years. Currently, a large amount of research is being carried out in order to determine the optimal surface topography for use in bioapplications, and thus the emphasis is on nanotechnology for biomedical applications. It was recently shown that titanium implants with rough surface topography and free energy increase osteoblast adhesion, maturation and subsequent bone formation. Furthermore, the adhesion of different cell lines to the surface of titanium implants is influenced by the surface characteristics of titanium; namely topography, charge distribution and chemistry. The present review article focuses on the specific nanotopography of titanium, i.e. titanium dioxide (TiO2) nanotubes, using a simple electrochemical anodisation method of the metallic substrate and other processes such as the hydrothermal or sol-gel template. One key advantage of using TiO2 nanotubes in cell interactions is based on the fact that TiO2 nanotube morphology is correlated with cell adhesion, spreading, growth and differentiation of mesenchymal stem cells, which were shown to be maximally induced on smaller diameter nanotubes (15 nm), but hindered on larger diameter (100 nm) tubes, leading to cell death and apoptosis. Research has supported the significance of nanotopography (TiO2 nanotube diameter) in cell adhesion and cell growth, and suggests that the mechanics of focal adhesion formation are similar among different cell types. As such, the present review will focus on perhaps the most spectacular and surprising one-dimensional structures and their unique biomedical applications for increased osseointegration, protein interaction and antibacterial properties.
- Published
- 2015
38. Fluorodeoxyglucose PET/CT and Tc99m-Sestamibi scan, dual tracer imaging in evaluation of osteonecrosis of jaw
- Author
-
Hrishikesh Joshi, Prathamesh Joshi, and Mukta Kulkarni
- Subjects
lcsh:RC648-665 ,business.industry ,Endocrinology, Diabetes and Metabolism ,lcsh:Diseases of the endocrine glands. Clinical endocrinology ,Tc99m Sestamibi ,Fluorodeoxyglucose PET ,Endocrinology ,Text mining ,Dual tracer ,Medicine ,lcsh:Diseases of the digestive system. Gastroenterology ,lcsh:RC799-869 ,Letters to the Editor ,business ,Nuclear medicine - Published
- 2012
39. Electrokinetic Properties of TiO2 Nanotubular Surfaces
- Author
-
Martina Lorenzetti, Aleš Iglič, Mukta Kulkarni, Ita Junkar, and Ekaterina Gongadze
- Subjects
Materials science ,Nanotechnology ,02 engineering and technology ,Electrolyte ,engineering.material ,010402 general chemistry ,01 natural sciences ,Electrokinetic phenomena ,Coating ,Materials Science(all) ,Zeta potential ,TiO2 nanotubes ,General Materials Science ,Surface charge ,Porosity ,Nano Express ,Anodizing ,021001 nanoscience & nanotechnology ,TiO2 nanostructured surfaces ,Condensed Matter Physics ,0104 chemical sciences ,Chemical engineering ,engineering ,Wetting ,Anodization ,0210 nano-technology - Abstract
Surface charge is one of the most significant properties for the characterisation of a biomaterial, being a key parameter in the interaction of the body implant with the surrounding living tissues. The present study concerns the systematic assessment of the surface charge of electrochemically anodized TiO2 nanotubular surfaces, proposed as coating material for Ti body implants. Biologically relevant electrolytes (NaCl, PBS, cell medium) were chosen to simulate the physiological conditions. The measurements were accomplished as titration curves at low electrolytic concentration (10(-3) M) and as single points at fixed pH but at various electrolytic concentrations (up to 0.1 M). The results showed that all the surfaces were negatively charged at physiological pH. However, the zeta potential values were dependent on the electrolytic conditions (electrolyte ion concentration, multivalence of the electrolyte ions, etc.) and on the surface characteristics (nanotubes top diameter, average porosity, exposed surface area, wettability, affinity to specific ions, etc.). Accordingly, various explanations were proposed to support the different experimental data among the surfaces. Theoretical model of electric double layer which takes into account the asymmetric finite size of ions in electrolyte and orientational ordering of water dipoles was modified according to our specific system in order to interpret the experimental data. Experimental results were in agreement with the theoretical predictions. Overall, our results contribute to enrich the state-of-art on the characterisation of nanostructured implant surfaces at the bio-interface, especially in case of topographically porous and rough surfaces.
- Full Text
- View/download PDF
40. OBSTACLES TO SUCCESS IN THE WORKPLACE FOR PEOPLE WITH DISABILITIES: A REVIEW AND RESEARCH AGENDA
- Author
-
TINA M. Mukta Kulkarni and Mark L. Lengnick-Hall
- Subjects
Disability, Workplace obstacles, Review ,jel:J71 - Abstract
Our objectives in this paper were to summarize research relevant to obstacles that people with disabilities (PWD) face in the workplace and to identify directions for future research on the topic. We included review, theoretical, and empirical articles in mainstream management journals and those in psychology or rehabilitation journals if they had clear workplace implications. We argue that obstacles identified in prior research may only partially reflect organizational reality. This is because of the heavy reliance on laboratory studies, which we urge researchers to replicate in organizational settings. Better understanding of obstacles will lead to more evidence-based solutions where the payoff is a less exclusionary world in which more individuals are provided opportunities to use their talent for the benefit of all. .
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.