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Your search keyword '"Moyna, Niall M."' showing total 315 results
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315 results on '"Moyna, Niall M."'

2. The impact of gas transfer on responses to exercise training in patients with pulmonary hypertension.

Author

McCormack, Ciara, Kehoe, Brona, McCullagh, Brian, Gaine, Sean, Moyna, Niall M., and Quadery, Syed Rehan

Subjects
EXERCISE therapy, PHYSICAL mobility, PULMONARY hypertension, PHYSICAL activity, LUNG volume measurements
Abstract

Exercise training is recommended for pulmonary hypertension (PH). Post hoc analysis of the PH and Home‐Based (PHAHB) trial stratified patients into two groups based on median diffusing capacity of the lungs for carbon monoxide (DLCO). Patients with higher DLCO had a greater improvement in physical activity performance in response to exercise training, compared to those with lower DLCO. DLCO may be an important consideration in prescribing exercise in PH. [ABSTRACT FROM AUTHOR]

Published
2024
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3. A dry immersion model of microgravity modulates platelet phenotype, miRNA signature, and circulating plasma protein biomarker profile

Author

Twomey, Laura, Navasiolava, Nastassia, Robin, Adrien, Bareille, Marie-Pierre, Gauquelin-Koch, Guillemette, Beck, Arnaud, Larcher, Françoise, Meade-Murphy, Gerardene, Sheridan, Sinead, Maguire, Patricia B., Harrison, Michael, Degryse, Bernard, Moyna, Niall M., Gharib, Claude, Custaud, Marc-Antoine, and Murphy, Ronan P.

Published
2021
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7. A polymorphism near IGF1 is associated with body composition and muscle function in women from the Health, Aging, and Body Composition Study

Author

Kostek, Matthew C., Devaney, Joseph M., Gordish-Dressman, Heather, Harris, Tamara B., Thompson, Paul D., Clarkson, Priscilla M., Angelopoulos, Theodore J., Gordon, Paul M., Moyna, Niall M., Pescatello, Linda S., Visich, Paul S., Zoeller, Robert F., Seip, Richard L., Garcia, Melissa, Li, Rongling, Zmuda, Joseph M., Delmonico, Matthew J., Kanaya, Alka, and Hoffman, Eric P.

Subjects
Biomedicine, Sports Medicine, Occupational Medicine/Industrial Medicine, Human Physiology, IGF1, Muscle, Body composition, Bone mineral density, Elderly, SNP
Abstract

Previous studies have reported associations of polymorphisms in the IGF1 gene with phenotypes of body composition (BC). The purpose of this study was to identify phenotypes of BC and physical function that were associated with the IGF1 promoter polymorphism (rs35767, −C1245T). Subjects from the Health, Aging, and Body Composition Study, white males and females (n = 925/836) and black males and females (533/705) aged 70–79 years were genotyped for the polymorphism. Phenotypes of muscle size and function, bone mineral density, and BC were analyzed for associations with this polymorphism. To validate and compare these findings, a cohort of young (mean age = 24.6, SD = 5.9) white men and women (n = 173/296) with similar phenotypic measurements were genotyped. An association with BC was identified in elderly females when significant covariates (physical activity, age, smoking status, body mass index) were included. White women with C/C genotype had 3% more trunk fat and 2% more total fat than those with C/T (P

Published
2010

28. AKT1 polymorphisms are associated with risk for metabolic syndrome

Author

Devaney, Joseph M., Gordish-Dressman, Heather, Harmon, Brennan T., Bradbury, Margaret K., Devaney, Stephanie A., Harris, Tamara B., Thompson, Paul D., Clarkson, Priscilla M., Price, Thomas B., Angelopoulos, Theodore J., Gordon, Paul M., Moyna, Niall M., Pescatello, Linda S., Visich, Paul S., Zoeller, Robert F., Seip, Richard L., Seo, Jinwook, Kim, Bo Hyoung, Tosi, Laura L., Garcia, Melissa, Li, Rongling, Zmuda, Joseph M., Delmonico, Matthew J., Lindsay, Robert S., Howard, Barbara V., Kraus, William E., and Hoffman, Eric P.

Published
2011
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30. SLC30A8 nonsynonymous variant is associated with recovery following exercise and skeletal muscle size and strength

Author

Sprouse, Courtney, Gordish-Dressman, Heather, Orkunoglu-Suer, E. Funda, Lipof, Jason S., Moeckel-Cole, Stephanie, Patel, Ronak R., Adham, Kasra, Larkin, Justin S., Hubal, Monica J., Kearns, Amy K., Clarkson, Priscilla M., Thompson, Paul D., Angelopoulos, Theodore J., Gordon, Paul M., Moyna, Niall M., Pescatello, Linda S., Visich, Paul S., Zoeller, Robert F., Hoffman, Eric P., Tosi, Laura L., and Devaney, Joseph M.

Subjects
Muscle strength -- Physiological aspects -- Health aspects -- Genetic aspects, Medical genetics -- Research, Isometric exercise -- Physiological aspects -- Health aspects -- Genetic aspects, Single nucleotide polymorphisms -- Health aspects, Type 2 diabetes -- Genetic aspects -- Risk factors, Allelomorphism -- Health aspects, Muscles -- Physiological aspects -- Health aspects -- Genetic aspects, Health
Abstract

Genome-wide association studies have identified thousands of variants that are associated with numerous phenotypes. One such variant, rs13266634, a nonsynonymous single nucleotide polymorphism in the solute carrier family 30 (zinc transporter) member eight gene, is associated with a 53% increase in the risk of developing type 2 diabetes (T2D). We hypothesized that individuals with the protective allele against T2D would show a positive response to short-term and long-term resistance exercise. Two cohorts of young adults--the Eccentric Muscle Damage (EMD; n = 156) cohort and the Functional Single Nucleotide Polymorphisms Associated with Muscle Size and Strength Study (FAMuSS; n = 874)--were tested for association of the rs13266634 variant with measures of skeletal muscle response to resistance exercise. Our results were sexually dimorphic in both cohorts. Men in the EMD study with two copies of the protective allele showed less post-exercise bout strength loss, less soreness, and lower creatine kinase values. In addition, men in the FAMuSS, homozygous for the protective allele, showed higher pre-exercise strength and larger arm skeletal muscle volume, but did not show a significant difference in skeletal muscle hypertrophy or strength with resistance training. Diabetes 2014;63:363-368 | DOI: 10.2337/db13-1150, Genome-wide association studies (GWASs) are extensively used as a tool to discover common single nucleotide polymorphisms (SNPs) associated with complex disease phenotypes such as type 2 diabetes (T2D), dyslipidemia, and [...]

Published
2014
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31. Response to Comment on Sprouse et al. SLC30A8 Nonsynonymous Variant Is Associated With Recovery Following Exercise and Skeletal Muscle Size and Strength. Diabetes 2014;63: 363–368

Author

Sprouse, Courtney, Gordish-Dressman, Heather, Orkunoglu-Suer, E. Funda, Lipof, Jason S., Moeckel-Cole, Stephanie, Patel, Ronak R., Adham, Kasra, Larkin, Justin S., Hubal, Monica J., Kearns, Amy K., Clarkson, Priscilla M., Thompson, Paul D., Angelopoulos, Theodore J., Gordon, Paul M., Moyna, Niall M., Pescatello, Linda S., Visich, Paul S., Zoeller, Robert F., Hoffman, Eric P., Tosi, Laura L., and Devaney, Joseph M.

Published
2014
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33. Feasibility, acceptability, and clinical effectiveness of a technology-enabled cardiac rehabilitation platform (Physical Activity Toward Health-I): randomized controlled trial

Author

ERC, Claes, Jomme, Cornelissen, Veronique A., McDermott, Clare, Moyna, Niall M., Pattyn, Nele, Cornelis, Nils, Gallagher, Anne, McCormack, Ciara, Newton, Helen, Gillain, Alexandra, Budts, Werner, Goetschalckx, Kaatje, Woods, Catherine B., Moran, Kieran A., Buys, Roselien, ERC, Claes, Jomme, Cornelissen, Veronique A., McDermott, Clare, Moyna, Niall M., Pattyn, Nele, Cornelis, Nils, Gallagher, Anne, McCormack, Ciara, Newton, Helen, Gillain, Alexandra, Budts, Werner, Goetschalckx, Kaatje, Woods, Catherine B., Moran, Kieran A., and Buys, Roselien

Abstract

peer-reviewed, BACKGROUND: Cardiac rehabilitation (CR) is highly effective as secondary prevention for cardiovascular diseases (CVDs). Uptake of CR remains suboptimal (30% of eligible patients), and long-term adherence to a physically active lifestyle is even lower. Innovative strategies are needed to counteract this phenomenon. OBJECTIVE: The Physical Activity Toward Health (PATHway) system was developed to provide a comprehensive, remotely monitored, home-based CR program for CVD patients. The PATHway-I study aimed to investigate its feasibility and clinical efficacy during phase III CR. METHODS: Participants were randomized on a 1:1 basis to the PATHway (PW) intervention group or usual care (UC) control group in a single-blind, multicenter, randomized controlled pilot trial. Outcomes were assessed at completion of phase II CR and 6-month follow-up. The primary outcome was physical activity (PA; Actigraph GT9X link). Secondary outcomes included measures of physical fitness, modifiable cardiovascular risk factors, endothelial function, intima-media thickness of the common carotid artery, and quality of life. System usability and patients' experiences were evaluated only in PW. A mixed-model analysis of variance with Bonferroni adjustment was used to analyze between-group effects over time. Missing values were handled by means of an intention-to-treat analysis. Statistical significance was set at a 2-sided alpha level of .05. Data are reported as mean (SD). RESULTS: A convenience sample of 120 CVD patients (mean 61.4 years, SD 13.5 years; 22 women) was included. The PATHway system was deployed in the homes of 60 participants. System use decreased over time and system usability was average with a score of 65.7 (SD 19.7; range 5-100). Moderate-to-vigorous intensity PA increased in PW (PW: 127 [SD 58] min to 141 [SD 69] min, UC: 146 [SD 66] min to 143 [SD 71] min; Pinteraction=.04; effect size of 0.42), while diastolic blood pressure (PW: 79 [SD 11] mmHg to 79 [SD 10] mmHg, UC: 78 [S, PUBLISHED, peer-reviewed

Published
2020

37. Leptin and Leptin Receptor Genetic Variants Associate with Habitual Physical Activity and Body Composition Changes in Response to Resistance Training: 993: June 3 1:30 PM - 1:45 PM

Author

Walsh, Sean, Haddad, Cedric J., Angelopoulos, Theodore J., Clarkson, Priscilla M., Gordon, Paul M., Moyna, Niall M., Visich, Paul S., Zoeller, Robert F., Bilbie, Steve, Seip, Richard L., Thompson, Paul D., Devaney, Joseph M., Gordish-Dressman, Heather, Hoffman, Eric P., Price, Thomas B., and Pescatello, Linda S.

Published
2011
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