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3. Creating a role model for “Academicians” Social Responsibility (ASR) synergizing with Swachh Bharat Abhiyaan: A campus hygiene initiative by PGIMER, Chandigarh

Author

Anand, Akshay, primary, Banik, Avijit, additional, Minhas, Gillipsie, additional, Bammidi, Sridhar, additional, Thakur, Keshav, additional, Sharma, Kaushal, additional, Tyagi, Rahul, additional, Modgil, Shweta, additional, Bali, Parul, additional, Sayal, Natasha, additional, Kaur, Paramvir, additional, Pal, Deepak Kumar, additional, Goyal, Atul Kumar, additional, Bhatt, Vinod, additional, Kaur, Navneet, additional, Kumar, Saurabh, additional, Saini, Jyoti, additional, Kaushal, Sushant, additional, Tiwari, Abha, additional, Ghani, Abdul, additional, Kaur, Gurkeerat, additional, Devi, Chandra, additional, Battu, Priya, additional, Khosla, Radhika, additional, Sharma, Kanupriya, additional, Sivapuram, Madhava Sai, additional, Podder, Vivek, additional, Singh, Amarjeet, additional, and Mehra, Priya, additional

Published
2019
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5. Chlorophyll rich biomolecular fraction of A. cadamba loaded into polymeric nanosystem coupled with Photothermal Therapy: A synergistic approach for cancer theranostics.

Author

Pemmaraju, Deepak, Appidi, Tejaswini, Minhas, Gillipsie, Singh, Surya Prakash, Khan, Nooruddin, Pal, Mahadeb, Srivastava, Rohit, Rengan, Aravind Kumar, Pemmaraju, Deepak, Appidi, Tejaswini, Minhas, Gillipsie, Singh, Surya Prakash, Khan, Nooruddin, Pal, Mahadeb, Srivastava, Rohit, and Rengan, Aravind Kumar

Abstract

Development of multifunctional biodegradable nanomaterials to encapsulate hydrophobic drugs and their triggered release in cancer theranostics is a challenge. In the current study, we report the encapsulation of potent anticancer − chlorophyll rich biomolecular fraction from the plant Anthocephalus cadamba into a polymeric nanosystem. The biomolecular fraction was combined with an NIR dye IR-780 to make it photo-thermally active. It was evaluated for its combinatorial (biomolecular extract and photothermal mediated) synergistic cytotoxicity in skin cancer cells. The inherent fluorescence of chlorophyll in the fraction was deployed to understand the cellular uptake and drug release. Cellular uptake of hydrophobic CFAc was enhanced with the aid of nanoformulation. It was observed that photo stability of IR-780 improved when incorporated with CFAc in polymeric nanosystem, which resulted in enhanced photothermal transduction efficiency. The combinational approach exhibited synergistic cytotoxicity which can be applied for skin cancer theranostics.

Published
2017

8. Allium cepaexerts neuroprotective effect on retinal ganglion cells of pterygopalatine artery (PPA) ligated mice

Author

Kumar, Saurabh, Modgil, Shweta, Bammidi, Sridhar, Minhas, Gillipsie, Shri, Richa, Kaushik, Sushmita, Singh, Varinder, and Anand, Akshay

Abstract

Repeated failure to rescue the damaged retinal ganglion cells (RGCs) by various drugs has warranted the need to screen common herbal compounds available in the form of various eye formulations for their efficacy.

Published
2020
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14. Neurosciences-2013

Author

Anand, Dr. Akshay, primary, Banik, Avijit, primary, Jindal, Neeru, primary, Minhas, Gillipsie, primary, Bammidi, Sridhar, primary, Tyagi, Rahul, primary, Sharma, Kaushal, primary, and Modgil, Shweta, primary

Published
2014
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18. Untitled.

Author

Minhas, Gillipsie and Anand, Akshay

Subjects
*ISCHEMIA, *BLOOD vessels
Abstract

Two images are presented which feature mouse retinal wholemounts showing vasculature in a retinal ischemia model.

Published
2015
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20. Association of ACL tears and single nucleotide polymorphisms in the collagen 12 A1 gene in the Indian population - a preliminary case-control study.

Author

John, Rakesh, Prabhakar, Sharad, Dhillon, Mandeep Singh, Anand, Akshay, and Minhas, Gillipsie

Subjects
*GENES, *GENETIC polymorphisms, *TEARS (Body fluid), *TENDON injuries, *CASE-control method, *GENOTYPES
Abstract

Background: Genetic predisposition to ACL tears has received tremendous interest in the past few years with many SNPs of different genes being linked to ACL tear. Study Objectives: To examine if specific sequence variants in COL12A1 gene are associated with ACL tears in Indian population. Study design: Case-control study. Materials and methods: 50 patients with surgically diagnosed ACL tear and 52 healthy, agematched controls without any ligament/tendon injuries were genotyped for rs970547 and rs240736 SNPs using real time PCR method. Results: The AG and GG genotypes were significantly under-represented in study group patients in rs970547 region (p=0.0361). However, there was no significant difference in genotype/allele frequencies in the rs240736 region. Conclusions: The COL12A1 rs970547 SNP is associated with ACL tears in the Indian population. However, these results need to be validated further so that predisposed individuals can be screened in the future for counselling and intervention. Level of evidence: III [ABSTRACT FROM AUTHOR]

Published
2016

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