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2. Postremission Consolidation by Autologous Hematopoietic Cell Transplantation (HCT) for Acute Myeloid Leukemia in First Complete Remission (CR) and Negative Implications for Subsequent Allogeneic HCT in Second CR: A Study by the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT)

Author

Passweg, J.R., Labopin, M., Christopeit, M., Cornelissen, J., Pabst, T., Socié, G., Russel, N., Yakoub-Agha, I., Blaise, D., Gedde-Dahl, T., Labussière-Wallet, H., Malladi, R., Forcade, E., Maury, S., Polge, E., Lanza, F., Gorin, N.C., Mohty, M., and Nagler, A.

Published
2020
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3. Long-term fatigue and quality of life among epithelial ovarian cancer survivors: a GINECO case/control VIVROVAIRE I study

Author

Joly, F., Ahmed-Lecheheb, D., Kalbacher, E., Heutte, N., Clarisse, B., Grellard, J.M., Gernier, F., Berton-Rigaud, D., Tredan, O., Fabbro, M., Savoye, A.M., Kurtz, J.E., Alexandre, J., Follana, P., Delecroix, V., Dohollou, N., Roemer-Becuwe, C., De Rauglaudre, G., Lortholary, A., Prulhiere, K., Lesoin, A., Zannetti, A., N’Guyen, S., Trager-Maury, S., Chauvenet, L., Abadie Lacourtoisie, S., Gompel, A., Lhommé, C., Floquet, A., and Pautier, P.

Published
2019
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5. Integrating biological HLA-DPB1 mismatch models to predict survival after unrelated hematopoietic cell transplantation

Author

Ruggeri, A, de Wreede, L, Muller, C, Crivello, P, Bonneville, E, Petersdorf, E, Socie, G, Dubois, V, Niittyvuopio, R, Perasaari, J, Yakoub-Agha, I, Cornelissen, J, Wieten, L, Gedde-Dahl, T, Forcade, E, Crawley, C, Marsh, S, Gandemer, V, Tholouli, E, Bulabois, C, Huynh, A, Choi, G, Deconinck, E, Itala-Remes, M, Lenhoff, S, Bengtsson, M, Johansson, J, van Gorkom, G, Hoogenboom, J, Vago, L, Rocha, V, Bonini, C, Chabannon, C, Fleischhauer, K, Clausen, J, Holter, W, Kalhs, P, Beguin, Y, Bron, D, Deeren, D, Lung, W, Kerre, T, Poire, X, Selleslag, D, Schroyens, W, Jindra, P, Mayer, J, Vydra, J, Zak, P, Nielsen, B, Sengeloev, H, Kaare, A, Partanen, A, Bay, J, Bertrand, Y, Blaise, D, Bourhis, J, Chevallier, P, Cluzeau, T, Damaj, G, Fegueux, N, Guyotat, D, Hunault-Berger, M, Labussiere-Wallet, H, Leleu, X, Lioure, B, Maury, S, Michel, G, Mohty, M, Rubio, M, Tilly, H, Turlure, P, Bethge, W, Casper, J, Einsele, H, Ganser, A, Kroger, N, Martin, S, Platzbecker, U, Reinhardt, C, Schafer-Eckart, K, Thurner, L, Valerius, T, Wulf, G, Karakasis, D, Spyridonidis, A, Hauser, P, Remenyi, P, Reykdal, S, Mousavi, A, Angelucci, E, Arcese, W, Benedetti, F, Bernasconi, P, Biondi, A, Bonifazi, F, Carella, A, Carluccio, P, Casini, M, Cavanna, L, Ciceri, F, Cimino, G, Corradini, P, Fanin, R, Galieni, P, Grillo, G, Iori, A, La Nasa, G, Locatelli, F, Marotta, G, Martino, M, Mazza, P, Mordini, N, Musso, M, Olivieri, A, Pavone, V, Pane, F, Petrini, M, Pioltelli, P, Rambaldi, A, Ruggeri, M, Saccardi, R, Santarone, S, Scime, R, Sica, S, Tarella, C, Velardi, A, Visani, G, Zecca, M, Tanase, A, Kulagin, A, Savchenko, V, Lopez, C, Amor, A, Lopez, J, Caballero, D, Duarte, R, Cascon, M, Porras, R, Perez-Simon, J, Rovira, M, Sanz, J, Carrete, J, Cammenga, J, Isaksson, C, Mielke, S, Chalandon, Y, Passweg, J, Schanz, U, Meijer, E, Kuball, J, Veelken, J, Apperley, J, Bloor, A, Byrne, J, Carpenter, B, Clark, A, Collin, M, Craddock, C, Gibson, B, Khan, A, Martin, M, Medd, P, Nicholson, E, Orchard, K, Patel, A, Peniket, A, Potter, V, Snowden, J, Wilson, K, Ruggeri A., de Wreede L. C., Muller C. R., Crivello P., Bonneville E. F., Petersdorf E. W., Socie G., Dubois V., Niittyvuopio R., Perasaari J., Yakoub-Agha I., Cornelissen J. J., Wieten L., Gedde-Dahl T., Forcade E., Crawley C. R., Marsh S. G. E., Gandemer V., Tholouli E., Bulabois C. -E., Huynh A., Choi G., Deconinck E., Itala-Remes M., Lenhoff S., Bengtsson M., Johansson J. -E., van Gorkom G., Hoogenboom J. D., Vago L., Rocha V., Bonini C., Chabannon C., Fleischhauer K., Clausen J., Holter W., Kalhs P., Beguin Y., Bron D., Deeren D., Lung W. K., Kerre T., Poire X., Selleslag D., Schroyens W., Jindra P., Mayer J., Vydra J., Zak P., Nielsen B., Sengeloev H., Kaare A., Partanen A., Bay J., Bertrand Y., Blaise D., Bourhis J. H., Chevallier P., Cluzeau T., Damaj G., Fegueux N., Guyotat D., Hunault-Berger M., Labussiere-Wallet H., Leleu X., Lioure B., Maury S., Michel G., Mohty M., Rubio M. T., Tilly H., Turlure P., Bethge W., Casper J., Einsele H., Ganser A., Kroger N., Martin S., Platzbecker U., Reinhardt C., Schafer-Eckart K., Thurner L., Valerius T., Wulf G. G., Karakasis D., Spyridonidis A., Hauser P., Remenyi P., Reykdal S., Mousavi A., Angelucci E., Arcese W., Benedetti F., Bernasconi P., Biondi A., Bonifazi F., Carella A. M., Carluccio P., Casini M., Cavanna L., Ciceri F., Cimino G., Corradini P., Fanin R., Galieni P., Grillo G., Iori A. P., La Nasa G., Locatelli F., Marotta G., Martino M., Mazza P., Mordini N., Musso M., Olivieri A., Pavone V., Pane F., Petrini M., Pioltelli P., Rambaldi A., Ruggeri M., Saccardi R., Santarone S., Scime R., Sica S., Tarella C., Velardi A., Visani G., Zecca M., Tanase A., Kulagin A., Savchenko V., Lopez C. A., Amor A. A., Lopez J. L. B., Caballero D., Duarte R., Cascon M. J. P., Porras R. P., Perez-Simon J. A., Rovira M., Sanz J., Carrete J. P. T., Cammenga J., Isaksson C., Mielke S., Chalandon Y., Passweg J., Schanz U., Meijer E., Kuball J., Veelken J. H., Apperley J., Bloor A., Byrne J., Carpenter B., Clark A., Collin M., Craddock C., Gibson B. E., Khan A., Martin M., Medd P., Nicholson E., Orchard K., Patel A., Peniket A., Potter V., Snowden J., Wilson K. M. O., Ruggeri, A, de Wreede, L, Muller, C, Crivello, P, Bonneville, E, Petersdorf, E, Socie, G, Dubois, V, Niittyvuopio, R, Perasaari, J, Yakoub-Agha, I, Cornelissen, J, Wieten, L, Gedde-Dahl, T, Forcade, E, Crawley, C, Marsh, S, Gandemer, V, Tholouli, E, Bulabois, C, Huynh, A, Choi, G, Deconinck, E, Itala-Remes, M, Lenhoff, S, Bengtsson, M, Johansson, J, van Gorkom, G, Hoogenboom, J, Vago, L, Rocha, V, Bonini, C, Chabannon, C, Fleischhauer, K, Clausen, J, Holter, W, Kalhs, P, Beguin, Y, Bron, D, Deeren, D, Lung, W, Kerre, T, Poire, X, Selleslag, D, Schroyens, W, Jindra, P, Mayer, J, Vydra, J, Zak, P, Nielsen, B, Sengeloev, H, Kaare, A, Partanen, A, Bay, J, Bertrand, Y, Blaise, D, Bourhis, J, Chevallier, P, Cluzeau, T, Damaj, G, Fegueux, N, Guyotat, D, Hunault-Berger, M, Labussiere-Wallet, H, Leleu, X, Lioure, B, Maury, S, Michel, G, Mohty, M, Rubio, M, Tilly, H, Turlure, P, Bethge, W, Casper, J, Einsele, H, Ganser, A, Kroger, N, Martin, S, Platzbecker, U, Reinhardt, C, Schafer-Eckart, K, Thurner, L, Valerius, T, Wulf, G, Karakasis, D, Spyridonidis, A, Hauser, P, Remenyi, P, Reykdal, S, Mousavi, A, Angelucci, E, Arcese, W, Benedetti, F, Bernasconi, P, Biondi, A, Bonifazi, F, Carella, A, Carluccio, P, Casini, M, Cavanna, L, Ciceri, F, Cimino, G, Corradini, P, Fanin, R, Galieni, P, Grillo, G, Iori, A, La Nasa, G, Locatelli, F, Marotta, G, Martino, M, Mazza, P, Mordini, N, Musso, M, Olivieri, A, Pavone, V, Pane, F, Petrini, M, Pioltelli, P, Rambaldi, A, Ruggeri, M, Saccardi, R, Santarone, S, Scime, R, Sica, S, Tarella, C, Velardi, A, Visani, G, Zecca, M, Tanase, A, Kulagin, A, Savchenko, V, Lopez, C, Amor, A, Lopez, J, Caballero, D, Duarte, R, Cascon, M, Porras, R, Perez-Simon, J, Rovira, M, Sanz, J, Carrete, J, Cammenga, J, Isaksson, C, Mielke, S, Chalandon, Y, Passweg, J, Schanz, U, Meijer, E, Kuball, J, Veelken, J, Apperley, J, Bloor, A, Byrne, J, Carpenter, B, Clark, A, Collin, M, Craddock, C, Gibson, B, Khan, A, Martin, M, Medd, P, Nicholson, E, Orchard, K, Patel, A, Peniket, A, Potter, V, Snowden, J, Wilson, K, Ruggeri A., de Wreede L. C., Muller C. R., Crivello P., Bonneville E. F., Petersdorf E. W., Socie G., Dubois V., Niittyvuopio R., Perasaari J., Yakoub-Agha I., Cornelissen J. J., Wieten L., Gedde-Dahl T., Forcade E., Crawley C. R., Marsh S. G. E., Gandemer V., Tholouli E., Bulabois C. -E., Huynh A., Choi G., Deconinck E., Itala-Remes M., Lenhoff S., Bengtsson M., Johansson J. -E., van Gorkom G., Hoogenboom J. D., Vago L., Rocha V., Bonini C., Chabannon C., Fleischhauer K., Clausen J., Holter W., Kalhs P., Beguin Y., Bron D., Deeren D., Lung W. K., Kerre T., Poire X., Selleslag D., Schroyens W., Jindra P., Mayer J., Vydra J., Zak P., Nielsen B., Sengeloev H., Kaare A., Partanen A., Bay J., Bertrand Y., Blaise D., Bourhis J. H., Chevallier P., Cluzeau T., Damaj G., Fegueux N., Guyotat D., Hunault-Berger M., Labussiere-Wallet H., Leleu X., Lioure B., Maury S., Michel G., Mohty M., Rubio M. T., Tilly H., Turlure P., Bethge W., Casper J., Einsele H., Ganser A., Kroger N., Martin S., Platzbecker U., Reinhardt C., Schafer-Eckart K., Thurner L., Valerius T., Wulf G. G., Karakasis D., Spyridonidis A., Hauser P., Remenyi P., Reykdal S., Mousavi A., Angelucci E., Arcese W., Benedetti F., Bernasconi P., Biondi A., Bonifazi F., Carella A. M., Carluccio P., Casini M., Cavanna L., Ciceri F., Cimino G., Corradini P., Fanin R., Galieni P., Grillo G., Iori A. P., La Nasa G., Locatelli F., Marotta G., Martino M., Mazza P., Mordini N., Musso M., Olivieri A., Pavone V., Pane F., Petrini M., Pioltelli P., Rambaldi A., Ruggeri M., Saccardi R., Santarone S., Scime R., Sica S., Tarella C., Velardi A., Visani G., Zecca M., Tanase A., Kulagin A., Savchenko V., Lopez C. A., Amor A. A., Lopez J. L. B., Caballero D., Duarte R., Cascon M. J. P., Porras R. P., Perez-Simon J. A., Rovira M., Sanz J., Carrete J. P. T., Cammenga J., Isaksson C., Mielke S., Chalandon Y., Passweg J., Schanz U., Meijer E., Kuball J., Veelken J. H., Apperley J., Bloor A., Byrne J., Carpenter B., Clark A., Collin M., Craddock C., Gibson B. E., Khan A., Martin M., Medd P., Nicholson E., Orchard K., Patel A., Peniket A., Potter V., Snowden J., and Wilson K. M. O.

Published
2023

8. A phase III trial of exemestane plus bevacizumab maintenance therapy in patients with metastatic breast cancer after first-line taxane and bevacizumab: a GINECO group study

Author

Trédan, O., Follana, P., Moullet, I., Cropet, C., Trager-Maury, S., Dauba, J., Lavau-Denes, S., Diéras, V., Béal-Ardisson, D., Gouttebel, M., Orfeuvre, H., Stefani, L., Jouannaud, C., Bürki, F., Petit, T., Guardiola, E., Becuwe, C., Blot, E., Pujade-Lauraine, E., and Bachelot, T.

Published
2016
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9. Global Climate

Author

Robert J. H. Dunn, Freya Aldred, Nadine Gobron, John B. Miller, Kate M. Willett, Melanie Ades, Robert Adler, R. P. Allan, John Anderson, Orlane Anneville, Yasuyuki Aono, Anthony Argüez, Carlo Arosio, John A. Augustine, Cesar Azorin-Molina, Jonathan Barichivich, Aman Basu, Hylke E. Beck, Nicolas Bellouin, Angela Benedetti, Kevin Blagrave, Stephen Blenkinsop, Olivier Bock, Xavier Bodin, Michael G. Bosilovich, Olivier Boucher, Gerald Bove, Dennis Buechler, Stefan A. Buehler, Laura Carrea, Kai-Lan Chang, Hanne H. Christiansen, John R. Christy, Eui-Seok Chung, Laura M. Ciasto, Melanie Coldewey-Egbers, Owen R. Cooper, Richard C. Cornes, Curt Covey, Thomas Cropper, Molly Crotwell, Diego Cusicanqui, Sean M. Davis, Richard A. M. de Jeu, Doug Degenstein, Reynald Delaloye, Markus G. Donat, Wouter A. Dorigo, Imke Durre, Geoff S. Dutton, Gregory Duveiller, James W. Elkins, Thomas W. Estilow, Nava Fedaeff, David Fereday, Vitali E. Fioletov, Johannes Flemming, Michael J. Foster, Stacey M. Frith, Lucien Froidevaux, Martin Füllekrug, Judith Garforth, Jay Garg, Matthew Gentry, Steven Goodman, Qiqi Gou, Nikolay Granin, Mauro Guglielmin, Sebastian Hahn, Leopold Haimberger, Brad D. Hall, Ian Harris, Debbie L. Hemming, Martin Hirschi, Shu-pen (Ben) Ho, Robert Holzworth, Filip Hrbáček, Daan Hubert, Petra Hulsman, Dale F. Hurst, Antje Inness, Ketil Isaksen, Viju O. John, Philip D. Jones, Robert Junod, Andreas Kääb, Johannes W. Kaiser, Viktor Kaufmann, Andreas Kellerer-Pirklbauer, Elizabeth C. Kent, Richard Kidd, Hyungiun Kim, Zak Kipling, Akash Koppa, Jan Henning L’Abée-Lund, Xin Lan, Kathleen O. Lantz, David Lavers, Norman G. Loeb, Diego Loyola, Remi Madelon, Hilmar J. Malmquist, Wlodzimierz Marszelewski, Michael Mayer, Matthew F. McCabe, Tim R. McVicar, Carl A. Mears, Annette Menzel, Christopher J. Merchant, Diego G. Miralles, Stephen A. Montzka, Colin Morice, Leander Mösinger, Jens Mühle, Julien P. Nicolas, Jeannette Noetzli, Tiina Nõges, Ben Noll, John O’Keefe, Tim J. Osborn, Taejin Park, Cecile Pellet, Maury S. Pelto, Sarah E. Perkins-Kirkpatrick, Coda Phillips, Stephen Po-Chedley, Lorenzo Polvani, Wolfgang Preimesberger, Colin Price, Merja Pulkkanen, Dominik G. Rains, William J. Randel, Samuel Rémy, Lucrezia Ricciardulli, Andrew D. Richardson, David A. Robinson, Matthew Rodell, Nemesio J. Rodríguez-Fernández, Karen H. Rosenlof, Chris Roth, Alexei Rozanov, This Rutishäuser, Ahira Sánchez-Lugo, Parnchai Sawaengphokhai, Verena Schenzinger, Robert W. Schlegel, Udo Schneider, Sapna Sharma, Lei Shi, Adrian J. Simmons, Carolina Siso, Sharon L. Smith, Brian J. Soden, Viktoria Sofieva, Tim H. Sparks, Paul W. Stackhouse, Ryan Stauffer, Wolfgang Steinbrecht, Andrea K. Steiner, Kenton Stewart, Pietro Stradiotti, Dimitri A. Streletskiy, Hagen Telg, Stephen J. Thackeray, Emmanuel Thibert, Michael Todt, Daisuke Tokuda, Kleareti Tourpali, Mari R. Tye, Ronald van der A, Robin van der Schalie, Gerard van der Schrier, Mendy van der Vliet, Guido R. van der Werf, Arnold. van Vliet, Jean-Paul Vernier, Isaac J. Vimont, Katrina Virts, Sebastiàn Vivero, Holger Vömel, Russell S. Vose, Ray H. J. Wang, Markus Weber, David Wiese, Jeanette D. Wild, Earle Williams, Takmeng Wong, R. I. Woolway, Xungang Yin, Ye Yuan, Lin Zhao, Xinjia Zhou, Jerry R. Ziemke, Markus Ziese, Ruxandra M. Zotta, Natural Environment Research Council (UK), European Commission, Department of Energy (US)an), Estonian Research Council, National Research Foundation of Korea, European Research Council, King Abdullah University of Science and Technology, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Fundación BBVA, Royal Society (UK), and NASA Astrobiology Institute (US)

Subjects
Atmospheric Science
Abstract

© Copyright 2022. Sociedad Meteorológica Estadounidense (AMS). Para obtener permiso para reutilizar cualquier parte de este Trabajo, comuníquese con permisos@ametsoc. org . Cualquier uso del material en este Trabajo que se determine como "uso justo" según la Sección 107 de la Ley de derechos de autor de EE. UU. (17 Código de EE. UU. § 107) o que cumpla las condiciones especificadas en la Sección 108 de la Ley de derechos de autor de EE. ) no requiere el permiso de la AMS. La republicación, la reproducción sistemática, la publicación en forma electrónica, como en un sitio web o en una base de datos de búsqueda, u otros usos de este material, excepto los exentos de la declaración anterior, requieren un permiso por escrito o una licencia de la AMS. Todas las publicaciones periódicas y monográficas de AMS están registradas en el Centro de Autorización de Derechos de Autor (https://www.copyright.com ). Se proporcionan detalles adicionales en la declaración de política de derechos de autor de AMS, disponible en el sitio web de AMS ( https://www.ametsoc.org/PUBSCopyrightPolicy ) ., In 2021, both social and economic activities began to return towards the levels preceding the COVID-19 pandemic for some parts of the globe, with others still experiencing restrictions. Meanwhile, the climate has continued to respond to the ongoing increase in greenhouse gases and resulting warming. La Niña, a phenomenon which tends to depress global temperatures while changing rainfall patterns in many regions, prevailed for all but two months of the year. Despite this, 2021 was one of the six-warmest years on record as measured by global mean surface temperature with an anomaly of between +0.21° and +0.28°C above the 1991–2020 climatology., Lake surface water temperatures from satellite data have been generated within the GloboLakes project funded by the UK National Environment Research Council (NE/J023345/2), with extensions funded by the EU Copernicus Climate Change Service (C3S) programme...

Published
2022
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10. Integrating biological HLA-DPB1 mismatch models to predict survival after unrelated hematopoietic cell transplantation

Author

Ruggeri, A., de Wreede, L. C., Muller, C. R., Crivello, P., Bonneville, E. F., Petersdorf, E. W., Socie, G., Dubois, V., Niittyvuopio, R., Perasaari, J., Yakoub-Agha, I., Cornelissen, J. J., Wieten, L., Gedde-Dahl, T., Forcade, E., Crawley, C. R., Marsh, S. G. E., Gandemer, V., Tholouli, E., Bulabois, C. -E., Huynh, A., Choi, G., Deconinck, E., Itala-Remes, M., Lenhoff, S., Bengtsson, M., Johansson, J. -E., van Gorkom, G., Hoogenboom, J. D., Vago, L., Rocha, V., Bonini, C., Chabannon, C., Fleischhauer, K., Clausen, J., Holter, W., Kalhs, P., Beguin, Y., Bron, D., Deeren, D., Lung, W. K., Kerre, T., Poire, X., Selleslag, D., Schroyens, W., Jindra, P., Mayer, J., Vydra, J., Zak, P., Nielsen, B., Sengeloev, H., Kaare, A., Partanen, A., Bay, J., Bertrand, Y., Blaise, D., Bourhis, J. H., Chevallier, P., Cluzeau, T., Damaj, G., Fegueux, N., Guyotat, D., Hunault-Berger, M., Labussiere-Wallet, H., Leleu, X., Lioure, B., Maury, S., Michel, G., Mohty, M., Rubio, M. T., Tilly, H., Turlure, P., Bethge, W., Casper, J., Einsele, H., Ganser, A., Kroger, N., Martin, S., Platzbecker, U., Reinhardt, C., Schafer-Eckart, K., Thurner, L., Valerius, T., Wulf, G. G., Karakasis, D., Spyridonidis, A., Hauser, P., Remenyi, P., Reykdal, S., Mousavi, A., Angelucci, E., Arcese, W., Benedetti, F., Bernasconi, P., Biondi, A., Bonifazi, F., Carella, A. M., Carluccio, P., Casini, M., Cavanna, L., Ciceri, F., Cimino, G., Corradini, P., Fanin, R., Galieni, P., Grillo, G., Iori, A. P., La Nasa, G., Locatelli, Franco, Marotta, G., Martino, M., Mazza, P., Mordini, N., Musso, M., Olivieri, A., Pavone, V., Pane, F., Petrini, M., Pioltelli, P., Rambaldi, A., Ruggeri, M., Saccardi, R., Santarone, S., Scime, R., Sica, S., Tarella, C., Velardi, A., Visani, G., Zecca, M., Tanase, A., Kulagin, A., Savchenko, V., Lopez, C. A., Amor, A. A., Lopez, J. L. B., Caballero, D., Duarte, R., Cascon, M. J. P., Porras, R. P., Perez-Simon, J. A., Rovira, M., Sanz, J., Carrete, J. P. T., Cammenga, J., Isaksson, C., Mielke, S., Chalandon, Y., Passweg, J., Schanz, U., Meijer, E., Kuball, J., Veelken, J. H., Apperley, J., Bloor, A., Byrne, J., Carpenter, B., Clark, A., Collin, M., Craddock, C., Gibson, B. E., Khan, A., Martin, M., Medd, P., Nicholson, E., Orchard, K., Patel, A., Peniket, A., Potter, V., Snowden, J., Wilson, K. M. O., Locatelli F. (ORCID:0000-0002-7976-3654), Ruggeri, A., de Wreede, L. C., Muller, C. R., Crivello, P., Bonneville, E. F., Petersdorf, E. W., Socie, G., Dubois, V., Niittyvuopio, R., Perasaari, J., Yakoub-Agha, I., Cornelissen, J. J., Wieten, L., Gedde-Dahl, T., Forcade, E., Crawley, C. R., Marsh, S. G. E., Gandemer, V., Tholouli, E., Bulabois, C. -E., Huynh, A., Choi, G., Deconinck, E., Itala-Remes, M., Lenhoff, S., Bengtsson, M., Johansson, J. -E., van Gorkom, G., Hoogenboom, J. D., Vago, L., Rocha, V., Bonini, C., Chabannon, C., Fleischhauer, K., Clausen, J., Holter, W., Kalhs, P., Beguin, Y., Bron, D., Deeren, D., Lung, W. K., Kerre, T., Poire, X., Selleslag, D., Schroyens, W., Jindra, P., Mayer, J., Vydra, J., Zak, P., Nielsen, B., Sengeloev, H., Kaare, A., Partanen, A., Bay, J., Bertrand, Y., Blaise, D., Bourhis, J. H., Chevallier, P., Cluzeau, T., Damaj, G., Fegueux, N., Guyotat, D., Hunault-Berger, M., Labussiere-Wallet, H., Leleu, X., Lioure, B., Maury, S., Michel, G., Mohty, M., Rubio, M. T., Tilly, H., Turlure, P., Bethge, W., Casper, J., Einsele, H., Ganser, A., Kroger, N., Martin, S., Platzbecker, U., Reinhardt, C., Schafer-Eckart, K., Thurner, L., Valerius, T., Wulf, G. G., Karakasis, D., Spyridonidis, A., Hauser, P., Remenyi, P., Reykdal, S., Mousavi, A., Angelucci, E., Arcese, W., Benedetti, F., Bernasconi, P., Biondi, A., Bonifazi, F., Carella, A. M., Carluccio, P., Casini, M., Cavanna, L., Ciceri, F., Cimino, G., Corradini, P., Fanin, R., Galieni, P., Grillo, G., Iori, A. P., La Nasa, G., Locatelli, Franco, Marotta, G., Martino, M., Mazza, P., Mordini, N., Musso, M., Olivieri, A., Pavone, V., Pane, F., Petrini, M., Pioltelli, P., Rambaldi, A., Ruggeri, M., Saccardi, R., Santarone, S., Scime, R., Sica, S., Tarella, C., Velardi, A., Visani, G., Zecca, M., Tanase, A., Kulagin, A., Savchenko, V., Lopez, C. A., Amor, A. A., Lopez, J. L. B., Caballero, D., Duarte, R., Cascon, M. J. P., Porras, R. P., Perez-Simon, J. A., Rovira, M., Sanz, J., Carrete, J. P. T., Cammenga, J., Isaksson, C., Mielke, S., Chalandon, Y., Passweg, J., Schanz, U., Meijer, E., Kuball, J., Veelken, J. H., Apperley, J., Bloor, A., Byrne, J., Carpenter, B., Clark, A., Collin, M., Craddock, C., Gibson, B. E., Khan, A., Martin, M., Medd, P., Nicholson, E., Orchard, K., Patel, A., Peniket, A., Potter, V., Snowden, J., Wilson, K. M. O., and Locatelli F. (ORCID:0000-0002-7976-3654)

Abstract

NO ABSTRACT

Published
2023

13. Global Climate

Author

Robert J. H. Dunn, F. Aldred, Nadine Gobron, John B. Miller, Kate M. Willett, M. Ades, Robert Adler, Richard, P. Allan, Rob Allan, J. Anderson, Anthony Argüez, C. Arosio, John A. Augustine, C. Azorin-Molina, J. Barichivich, H. E. Beck, Andreas Becker, Nicolas Bellouin, Angela Benedetti, David I. Berry, Stephen Blenkinsop, Olivier Bock, X. Bodin, Michael G. Bosilovich, Olivier Boucher, S. A. Buehler, B. Calmettes, Laura Carrea, Laura Castia, Hanne H. Christiansen, John R. Christy, E.-S. Chung, Melanie Coldewey-Egbers, Owen R. Cooper, Richard C. Cornes, Curt Covey, J.-F. Cretaux, M. Crotwell, Sean M. Davis, Richard A. M. de Jeu, Doug Degenstein, R. Delaloye, Larry Di Girolamo, Markus G. Donat, Wouter A. Dorigo, Imke Durre, Geoff S. Dutton, Gregory Duveiller, James W. Elkins, Vitali E. Fioletov, Johannes Flemming, Michael J. Foster, Stacey M. Frith, Lucien Froidevaux, J. Garforth, Matthew Gentry, S. K. Gupta, S. Hahn, Leopold Haimberger, Brad D. Hall, Ian Harris, D. L. Hemming, M. Hirschi, Shu-pen (Ben) Ho, F. Hrbacek, Daan Hubert, Dale F. Hurst, Antje Inness, K. Isaksen, Viju O. John, Philip D. Jones, Robert Junod, J. W. Kaiser, V. Kaufmann, A. Kellerer-Pirklbauer, Elizabeth C. Kent, R. Kidd, Hyungjun Kim, Z. Kipling, A. Koppa, B. M. Kraemer, D. P. Kratz, Xin Lan, Kathleen O. Lantz, D. Lavers, Norman G. Loeb, Diego Loyola, R. Madelon, Michael Mayer, M. F. McCabe, Tim R. McVicar, Carl A. Mears, Christopher J. Merchant, Diego G. Miralles, L. Moesinger, Stephen A. Montzka, Colin Morice, L. Mösinger, Jens Mühle, Julien P. Nicolas, Jeannette Noetzli, Ben Noll, J. O’Keefe, Tim J. Osborn, T. Park, A. J. Pasik, C. Pellet, Maury S. Pelto, S. E. Perkins-Kirkpatrick, G. Petron, Coda Phillips, S. Po-Chedley, L. Polvani, W. Preimesberger, D. G. Rains, W. J. Randel, Nick A. Rayner, Samuel Rémy, L. Ricciardulli, A. D. Richardson, David A. Robinson, Matthew Rodell, N. J. Rodríguez-Fernández, K.H. Rosenlof, C. Roth, A. Rozanov, T. Rutishäuser, Ahira Sánchez-Lugo, P. Sawaengphokhai, T. Scanlon, Verena Schenzinger, R. W. Schlegel, S. Sharma, Lei Shi, Adrian J. Simmons, Carolina Siso, Sharon L. Smith, B. J. Soden, Viktoria Sofieva, T. H. Sparks, Paul W. Stackhouse, Wolfgang Steinbrecht, Martin Stengel, Dimitri A. Streletskiy, Sunny Sun-Mack, P. Tans, S. J. Thackeray, E. Thibert, D. Tokuda, Kleareti Tourpali, Mari R. Tye, Ronald van der A, Robin van der Schalie, Gerard van der Schrier, M. van der Vliet, Guido R. van der Werf, A. Vance, Jean-Paul Vernier, Isaac J. Vimont, Holger Vömel, Russell S. Vose, Ray Wang, Markus Weber, David Wiese, Anne C. Wilber, Jeanette D. Wild, Takmeng Wong, R. Iestyn Woolway, Xinjia Zhou, Xungang Yin, Guangyu Zhao, Lin Zhao, Jerry R. Ziemke, Markus Ziese, and R. M. Zotta

Subjects
Atmospheric Science, Index (economics), 010504 meteorology & atmospheric sciences, Global climate, 0207 environmental engineering, 02 engineering and technology, Annual report, State (functional analysis), 01 natural sciences, 13. Climate action, Climatology, Environmental monitoring, Environmental science, 020701 environmental engineering, 0105 earth and related environmental sciences
Abstract

Global Climate is one chapter from the State of the Climate in 2019 annual report and is avail- able from https://doi.org/10.1175/BAMS-D-20-0104.1 Compiled by NOAA’s National Centers for Environmental Information, State of the Climate in 2019 is based on contributions from scien- tists from around the world. It provides a detailed update on global climate indicators, notable weather events, and other data collected by environmental monitoring stations and instru- ments located on land, water, ice, and in space. The full report is available from https://doi.org/10.1175/2020BAMSStateoftheClimate.1.

Published
2021
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16. Global Climate:STATE OF THE CLIMATE IN 2021

Author

Ades, Melanie, Adler, Robert, Aldred, Freya, Allan, R. P., Anderson, John, Anneville, Orlane, Aono, Yasuyuki, Argüez, Anthony, Arosio, Carlo, Augustine, John A., Azorin-Molina, Cesar, Barichivich, Jonathan, Basu, Aman, Beck, Hylke E., Bellouin, Nicolas, Benedetti, Angela, Blagrave, Kevin, Blenkinsop, Stephen, Bock, Olivier, Bodin, Xavier, Bosilovich, Michael G., Boucher, Olivier, Bove, Gerald, Buechler, Dennis, Buehler, Stefan A., Carrea, Laura, Chang, Kai Lan, Christiansen, Hanne H., Christy, John R., Chung, Eui Seok, Ciasto, Laura M., Coldewey-Egbers, Melanie, Cooper, Owen R., Cornes, Richard C., Covey, Curt, Cropper, Thomas, Crotwell, Molly, Cusicanqui, Diego, Davis, Sean M., de Jeu, Richard A.M., Degenstein, Doug, Delaloye, Reynald, Donat, Markus G., Dorigo, Wouter A., Dunn, Robert J.H., Durre, Imke, Dutton, Geoff S., Duveiller, Gregory, Elkins, James W., Estilow, Thomas W., Fedaeff, Nava, Fereday, David, Fioletov, Vitali E., Flemming, Johannes, Foster, Michael J., Frith, Stacey M., Froidevaux, Lucien, Füllekrug, Martin, Garforth, Judith, Garg, Jay, Gentry, Matthew, Gobron, Nadine, Goodman, Steven, Gou, Qiqi, Granin, Nikolay, Guglielmin, Mauro, Hahn, Sebastian, Haimberger, Leopold, Hall, Brad D., Harris, Ian, Hemming, Debbie L., Hirschi, Martin, Ho, Shu Pen, Holzworth, Robert, Hrbáček, Filip, Hubert, Daan, Hulsman, Petra, Hurst, Dale F., Inness, Antje, Isaksen, Ketil, John, Viju O., Jones, Philip D., Junod, Robert, Kääb, Andreas, Kaiser, Johannes W., Kaufmann, Viktor, Kellerer-Pirklbauer, Andreas, Kent, Elizabeth C., Kidd, Richard, Kim, Hyungiun, Kipling, Zak, Koppa, Akash, L'Abée-Lund, Jan Henning, Lan, Xin, Lantz, Kathleen O., Lavers, David, Loeb, Norman G., Loyola, Diego, Madelon, Remi, Malmquist, Hilmar J., Marszelewski, Wlodzimierz, Mayer, Michael, McCabe, Matthew F., McVicar, Tim R., Mears, Carl A., Menzel, Annette, Merchant, Christopher J., Miller, John B., Miralles, Diego G., Montzka, Stephen A., Morice, Colin, Mösinger, Leander, Mühle, Jens, Nicolas, Julien P., Noetzli, Jeannette, Nõges, Tiina, Noll, Ben, O'Keefe, John, Osborn, Tim J., Park, Taejin, Pellet, Cecile, Pelto, Maury S., Perkins-Kirkpatrick, Sarah E., Phillips, Coda, Po-Chedley, Stephen, Polvani, Lorenzo, Preimesberger, Wolfgang, Price, Colin, Pulkkanen, Merja, Rains, Dominik G., Randel, William J., Rémy, Samuel, Ricciardulli, Lucrezia, Richardson, Andrew D., Robinson, David A., Rodell, Matthew, Rodríguez-Fernández, Nemesio J., Rosenlof, Karen H., Roth, Chris, Rozanov, Alexei, Rutishäuser, This, Sánchez-Lugo, Ahira, Sawaengphokhai, Parnchai, Schenzinger, Verena, Schlegel, Robert W., Schneider, Udo, Sharma, Sapna, Shi, Lei, Simmons, Adrian J., Siso, Carolina, Smith, Sharon L., Soden, Brian J., Sofieva, Viktoria, Sparks, Tim H., Stackhouse, Paul W., Stauffer, Ryan, Steinbrecht, Wolfgang, Steiner, Andrea K., Stewart, Kenton, Stradiotti, Pietro, Streletskiy, Dimitri A., Telg, Hagen, Thackeray, Stephen J., Thibert, Emmanuel, Todt, Michael, Tokuda, Daisuke, Tourpali, Kleareti, Tye, Mari R., Van Der, A. Ronald, van der Schalie, Robin, van der Schrier, Gerard, van der Vliet, Mendy, van der Werf, Guido R., van Vliet, Arnold, Vernier, Jean Paul, Vimont, Isaac J., Virts, Katrina, Vivero, Sebastiàn, Vömel, Holger, Vose, Russell S., Wang, Ray H.J., Weber, Markus, Wiese, David, Wild, Jeanette D., Willett, Kate M., Williams, Earle, Wong, Takmeng, Woolway, R. I., Yin, Xungang, Yuan, Ye, Zhao, Lin, Zhou, Xinjia, Ziemke, Jerry R., Ziese, Markus, Zotta, Ruxandra M., Allen, Jessicca, Camper, Amy, Hammer, Gregory, Love-Brotak, S. Elizabeth, Misch, Deborah J., Ohlmann, Laura, Riddle, Deborah B., Veasey, Sara W., Earth and Climate, Earth Sciences, and Amsterdam Sustainability Institute

Published
2022
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17. Global Climate

Author

Dunn, Robert J. H., primary, Aldred, Freya, additional, Gobron, Nadine, additional, Miller, John B., additional, Willett, Kate M., additional, Ades, Melanie, additional, Adler, Robert, additional, Allan, R. P., additional, Anderson, John, additional, Anneville, Orlane, additional, Aono, Yasuyuki, additional, Argüez, Anthony, additional, Arosio, Carlo, additional, Augustine, John A., additional, Azorin-Molina, Cesar, additional, Barichivich, Jonathan, additional, Basu, Aman, additional, Beck, Hylke E., additional, Bellouin, Nicolas, additional, Benedetti, Angela, additional, Blagrave, Kevin, additional, Blenkinsop, Stephen, additional, Bock, Olivier, additional, Bodin, Xavier, additional, Bosilovich, Michael G., additional, Boucher, Olivier, additional, Bove, Gerald, additional, Buechler, Dennis, additional, Buehler, Stefan A., additional, Carrea, Laura, additional, Chang, Kai-Lan, additional, Christiansen, Hanne H., additional, Christy, John R., additional, Chung, Eui-Seok, additional, Ciasto, Laura M., additional, Coldewey-Egbers, Melanie, additional, Cooper, Owen R., additional, Cornes, Richard C., additional, Covey, Curt, additional, Cropper, Thomas, additional, Crotwell, Molly, additional, Cusicanqui, Diego, additional, Davis, Sean M., additional, de Jeu, Richard A. M., additional, Degenstein, Doug, additional, Delaloye, Reynald, additional, Donat, Markus G., additional, Dorigo, Wouter A., additional, Durre, Imke, additional, Dutton, Geoff S., additional, Duveiller, Gregory, additional, Elkins, James W., additional, Estilow, Thomas W., additional, Fedaeff, Nava, additional, Fereday, David, additional, Fioletov, Vitali E., additional, Flemming, Johannes, additional, Foster, Michael J., additional, Frith, Stacey M., additional, Froidevaux, Lucien, additional, Füllekrug, Martin, additional, Garforth, Judith, additional, Garg, Jay, additional, Gentry, Matthew, additional, Goodman, Steven, additional, Gou, Qiqi, additional, Granin, Nikolay, additional, Guglielmin, Mauro, additional, Hahn, Sebastian, additional, Haimberger, Leopold, additional, Hall, Brad D., additional, Harris, Ian, additional, Hemming, Debbie L., additional, Hirschi, Martin, additional, Ho, Shu-pen (Ben), additional, Holzworth, Robert, additional, Hrbáček, Filip, additional, Hubert, Daan, additional, Hulsman, Petra, additional, Hurst, Dale F., additional, Inness, Antje, additional, Isaksen, Ketil, additional, John, Viju O., additional, Jones, Philip D., additional, Junod, Robert, additional, Kääb, Andreas, additional, Kaiser, Johannes W., additional, Kaufmann, Viktor, additional, Kellerer-Pirklbauer, Andreas, additional, Kent, Elizabeth C., additional, Kidd, Richard, additional, Kim, Hyungiun, additional, Kipling, Zak, additional, Koppa, Akash, additional, L’Abée-Lund, Jan Henning, additional, Lan, Xin, additional, Lantz, Kathleen O., additional, Lavers, David, additional, Loeb, Norman G., additional, Loyola, Diego, additional, Madelon, Remi, additional, Malmquist, Hilmar J., additional, Marszelewski, Wlodzimierz, additional, Mayer, Michael, additional, McCabe, Matthew F., additional, McVicar, Tim R., additional, Mears, Carl A., additional, Menzel, Annette, additional, Merchant, Christopher J., additional, Miralles, Diego G., additional, Montzka, Stephen A., additional, Morice, Colin, additional, Mösinger, Leander, additional, Mühle, Jens, additional, Nicolas, Julien P., additional, Noetzli, Jeannette, additional, Nõges, Tiina, additional, Noll, Ben, additional, O’Keefe, John, additional, Osborn, Tim J., additional, Park, Taejin, additional, Pellet, Cecile, additional, Pelto, Maury S., additional, Perkins-Kirkpatrick, Sarah E., additional, Phillips, Coda, additional, Po-Chedley, Stephen, additional, Polvani, Lorenzo, additional, Preimesberger, Wolfgang, additional, Price, Colin, additional, Pulkkanen, Merja, additional, Rains, Dominik G., additional, Randel, William J., additional, Rémy, Samuel, additional, Ricciardulli, Lucrezia, additional, Richardson, Andrew D., additional, Robinson, David A., additional, Rodell, Matthew, additional, Rodríguez-Fernández, Nemesio J., additional, Rosenlof, Karen H., additional, Roth, Chris, additional, Rozanov, Alexei, additional, Rutishäuser, This, additional, Sánchez-Lugo, Ahira, additional, Sawaengphokhai, Parnchai, additional, Schenzinger, Verena, additional, Schlegel, Robert W., additional, Schneider, Udo, additional, Sharma, Sapna, additional, Shi, Lei, additional, Simmons, Adrian J., additional, Siso, Carolina, additional, Smith, Sharon L., additional, Soden, Brian J., additional, Sofieva, Viktoria, additional, Sparks, Tim H., additional, Stackhouse, Paul W., additional, Stauffer, Ryan, additional, Steinbrecht, Wolfgang, additional, Steiner, Andrea K., additional, Stewart, Kenton, additional, Stradiotti, Pietro, additional, Streletskiy, Dimitri A., additional, Telg, Hagen, additional, Thackeray, Stephen J., additional, Thibert, Emmanuel, additional, Todt, Michael, additional, Tokuda, Daisuke, additional, Tourpali, Kleareti, additional, Tye, Mari R., additional, van der A, Ronald, additional, van der Schalie, Robin, additional, van der Schrier, Gerard, additional, van der Vliet, Mendy, additional, van der Werf, Guido R., additional, van Vliet, Arnold., additional, Vernier, Jean-Paul, additional, Vimont, Isaac J., additional, Virts, Katrina, additional, Vivero, Sebastiàn, additional, Vömel, Holger, additional, Vose, Russell S., additional, Wang, Ray H. J., additional, Weber, Markus, additional, Wiese, David, additional, Wild, Jeanette D., additional, Williams, Earle, additional, Wong, Takmeng, additional, Woolway, R. I., additional, Yin, Xungang, additional, Yuan, Ye, additional, Zhao, Lin, additional, Zhou, Xinjia, additional, Ziemke, Jerry R., additional, Ziese, Markus, additional, and Zotta, Ruxandra M., additional

Published
2022
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18. PB2115: TRIAL IN PROGRESS: A RANDOMIZED PHASE II STUDY OF MB-CART2019.1 COMPARED TO STANDARD OF CARE THERAPY IN PATIENTS WITH RELAPSED/REFRACTORY DLBCL INELIGIBLE FOR AUTOLOGOUS STEM CELL TRANSPLANTATION

Author

Borchmann, P., primary, Vandenberghe, P., additional, Urbano, A., additional, Haioun, C., additional, Lemonnier, F., additional, Griškevicius, L., additional, Maury, S., additional, Holtkamp, S., additional, Friedrichs, B., additional, Zadoyan, G., additional, Hanssens, L., additional, Brillant, C., additional, Bethke, U., additional, Assenmacher, M., additional, Bürger, I., additional, Philippe, B., additional, Overstijns, T., additional, Jäger, U., additional, and Kersten, M. J., additional

Published
2022
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19. Épigénétique

Author

Jammes, Hélène, Boudry, Pierre, and Maury, Stéphane

Subjects
genetic improvement, aquaculture, bacteria, biology, molecular biology, biotechnology, breeding, epigenetics, genetics, history, nutrition, GMO, plant pathology, philosophy, fish, research, reproduction, health, technology, virus, Genetics (non-medical)
Abstract

In this book, epigenetics is understood as the science of molecules and mechanisms involved in controlling gene activity without altering their sequence, and which thus contribute to cellular functions. It enables us to decipher the development and differentiation processes of cells in a complex organism, which perform different functions despite sharing the same nuclear genetic information. This science also supports cellular memory and responses to the environment. The book introduces the history and evolution of the concept of "epigenetics" and explains the molecular mechanisms that govern the development of mammals, fish or plants. Knowledge of the diversity of these mechanisms, and our understanding of their importance in biology, is probably just getting started. Some processes, such as X chromosome inactivation, are specific to mammals, while others, such as parental imprinting, are surprisingly common to both mammals and plants with sexual reproduction. Their importance in responses to the biotic or abiotic environment is highlighted to show possible applications in medicine or agronomy. This book is intended for students, teachers in higher education and researchers in the field of biology.

Published
2024
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20. Global Climate

Author

Natural Environment Research Council (UK), European Commission, Department of Energy (US)an), Estonian Research Council, National Research Foundation of Korea, European Research Council, King Abdullah University of Science and Technology, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Fundación BBVA, Royal Society (UK), NASA Astrobiology Institute (US), Dunn, Robert J. H., Aldred, Freya, Gobron, Nadine, Miller, John B., Willett, Kate M., Ades, Melanie, Adler, Robert, Allan, R. P., Anderson, John, Anneville, Orlane, Aono, Yasuyuki, Argüez, Anthony, Arosio, Carlo, Augustine, John A., Azorín-Molina, César, Barichivich, Jonathan, Basu, Aman, Beck, Hylke E., Bellouin, Nicolas, Benedetti, Angela, Blagrave, Kevin, Blenkinsop, Stephen, Bock, Olivier, Bodin, Xavier, Bosilovich, Michael G., Boucher, Olivier, Bove, Gerald, Buechler, Dennis, Buehler, Stefan A., Carrea, Laura, Chang, Kai-Lan, Christiansen, Hanne H., Christy, John R., Chung, Eui-Seok, Ciasto, Laura M., Coldewey-Egbers, Melanie, Cooper, Owen R., Cornes, Richard C., Covey, Curt, Cropper, Thomas, Crotwell, Molly, Cusicanqui, Diego, Davis, Sean M., Jeu, Richard A. M. de, Degenstein, Doug, Delaloye, Reynald, Donat, Markus G., Dorigo, Wouter A., Durre, Imke, Dutton, Geoff S., Duveiller, Gregory, Elkins, James W., Estilow, Thomas W., Fedaeff, Nava, Fereday, David, Fioletov, Vitali E., Flemming, Johannes, Foster, Michael J., Frith, Stacey M., Froidevaux, Lucien, Füllekrug, Martin, Garforth, Judith, Garg, Jay, Gentry, Matthew, Goodman, Steven, Gou, Qiqi, Granin, Nikolay, Guglielmin, Mauro, Hahn, Sebastian, Haimberger, Leopold, Hall, Brad D., Harris, Ian, Hemming, Debbie L., Hirschi, Martin, Ho, Shu-pen (Ben), Holzworth, Robert, Hrbáček, Filip, Hubert, Daan, Hulsman, Petra, Hurst, Dale F., Inness, Antje, Isaksen, Ketil, John, Viju O., Jones, Philip D., Junod, Robert, Kääb, Andreas, Kaiser, Johannes W., Kaufmann, Viktor, Kellerer-Pirklbauer, Andreas, Kent, Elizabeth C., Kidd, Richard, Kim, Hyungiun, Kipling, Zak, Koppa, Akash, Henning L’Abée-Lund, Jan, Lan, Xin, Lantz, Kathleen O., Lavers, David, Loeb, Norman G., Loyola, Diego, Madelon, Remi, Malmquist, Hilmar J., Marszelewski, Wlodzimierz, Mayer, Michael, McCabe, Matthew F., McVicar, Tim R., Mears, Carl A., Menzel, Annette, Merchant, Christopher J., Miralles, Diego G., Montzka, Stephen A., Morice, Colin, Mösinger, Leander, Mühle, Jens, Nicolas, Julien P., Noetzli, Jeannette, Nõges, Tiina, Noll, Ben, O’Keefe, John, Osborn, Tim J., Park, Taejin, Pellet, Cecile, Pelto, Maury S., Perkins-Kirkpatrick, Sarah E., Phillips, Coda, Po-Chedley, Stephen, Polvani, Lorenzo, Preimesberger, Wolfgang, Price, Colin, Pulkkanen, Merja, Rains, Dominik G., Randel, William J., Rémy, Samuel, Ricciardulli, Lucrezia, Richardson, Andrew D., Robinson, David A., Rodell, Matthew, Rodríguez-Fernández, Nemesio J., Rosenlof, Karen H., Roth, Chris, Rozanov, Alexei, Rutishäuser, This, Sánchez-Lugo, Ahira, Sawaengphokhai, Parnchai, Schenzinger, Verena, Schlegel, Robert W., Schneider, Udo, Sharma, Sapna, Shi, Lei, Simmons, Adrian J., Siso, Carolina, Smith, Sharon L., Soden, Brian J., Sofieva, Viktoria, Sparks, Tim H., Stackhouse Jr., Paul W., Stauffer, Ryan, Steinbrecht, Wolfgang, Steiner, Andrea K., Stewart, Kenton, Stradiotti, Pietro, Streletskiy, Dimitri A., Telg, Hagen, Thackeray, Stephen J., Thibert, Emmanuel, Todt, Michael, Tokuda, Daisuke, Tourpali, Kleareti, Tye, Mari R., Van der A, Ronald, Schalie, Robin van der, Schrier, Gerard van der, Vliet, Mendy van der, Werf, Guido R. van der, Vliet, Arnold. van, Vernier, Jean-Paul, Vimont, Isaac J., Virts, Katrina, Vivero, Sebastiàn, Vömel, Holger, Vose, Russell S., Wang, Ray H. J., Weber, Markus, Wiese, David, Wild, Jeanette D., Williams, Earle, Wong, Takmeng, Woolway, R. Iestyn, Yin, Xungang, Yuan, Ye, Zhao, Lin, Zhou, Xinjia, Ziemke, Jerry R., Ziese, Markus, Zotta, Ruxandra M., Natural Environment Research Council (UK), European Commission, Department of Energy (US)an), Estonian Research Council, National Research Foundation of Korea, European Research Council, King Abdullah University of Science and Technology, Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Fundación BBVA, Royal Society (UK), NASA Astrobiology Institute (US), Dunn, Robert J. H., Aldred, Freya, Gobron, Nadine, Miller, John B., Willett, Kate M., Ades, Melanie, Adler, Robert, Allan, R. P., Anderson, John, Anneville, Orlane, Aono, Yasuyuki, Argüez, Anthony, Arosio, Carlo, Augustine, John A., Azorín-Molina, César, Barichivich, Jonathan, Basu, Aman, Beck, Hylke E., Bellouin, Nicolas, Benedetti, Angela, Blagrave, Kevin, Blenkinsop, Stephen, Bock, Olivier, Bodin, Xavier, Bosilovich, Michael G., Boucher, Olivier, Bove, Gerald, Buechler, Dennis, Buehler, Stefan A., Carrea, Laura, Chang, Kai-Lan, Christiansen, Hanne H., Christy, John R., Chung, Eui-Seok, Ciasto, Laura M., Coldewey-Egbers, Melanie, Cooper, Owen R., Cornes, Richard C., Covey, Curt, Cropper, Thomas, Crotwell, Molly, Cusicanqui, Diego, Davis, Sean M., Jeu, Richard A. M. de, Degenstein, Doug, Delaloye, Reynald, Donat, Markus G., Dorigo, Wouter A., Durre, Imke, Dutton, Geoff S., Duveiller, Gregory, Elkins, James W., Estilow, Thomas W., Fedaeff, Nava, Fereday, David, Fioletov, Vitali E., Flemming, Johannes, Foster, Michael J., Frith, Stacey M., Froidevaux, Lucien, Füllekrug, Martin, Garforth, Judith, Garg, Jay, Gentry, Matthew, Goodman, Steven, Gou, Qiqi, Granin, Nikolay, Guglielmin, Mauro, Hahn, Sebastian, Haimberger, Leopold, Hall, Brad D., Harris, Ian, Hemming, Debbie L., Hirschi, Martin, Ho, Shu-pen (Ben), Holzworth, Robert, Hrbáček, Filip, Hubert, Daan, Hulsman, Petra, Hurst, Dale F., Inness, Antje, Isaksen, Ketil, John, Viju O., Jones, Philip D., Junod, Robert, Kääb, Andreas, Kaiser, Johannes W., Kaufmann, Viktor, Kellerer-Pirklbauer, Andreas, Kent, Elizabeth C., Kidd, Richard, Kim, Hyungiun, Kipling, Zak, Koppa, Akash, Henning L’Abée-Lund, Jan, Lan, Xin, Lantz, Kathleen O., Lavers, David, Loeb, Norman G., Loyola, Diego, Madelon, Remi, Malmquist, Hilmar J., Marszelewski, Wlodzimierz, Mayer, Michael, McCabe, Matthew F., McVicar, Tim R., Mears, Carl A., Menzel, Annette, Merchant, Christopher J., Miralles, Diego G., Montzka, Stephen A., Morice, Colin, Mösinger, Leander, Mühle, Jens, Nicolas, Julien P., Noetzli, Jeannette, Nõges, Tiina, Noll, Ben, O’Keefe, John, Osborn, Tim J., Park, Taejin, Pellet, Cecile, Pelto, Maury S., Perkins-Kirkpatrick, Sarah E., Phillips, Coda, Po-Chedley, Stephen, Polvani, Lorenzo, Preimesberger, Wolfgang, Price, Colin, Pulkkanen, Merja, Rains, Dominik G., Randel, William J., Rémy, Samuel, Ricciardulli, Lucrezia, Richardson, Andrew D., Robinson, David A., Rodell, Matthew, Rodríguez-Fernández, Nemesio J., Rosenlof, Karen H., Roth, Chris, Rozanov, Alexei, Rutishäuser, This, Sánchez-Lugo, Ahira, Sawaengphokhai, Parnchai, Schenzinger, Verena, Schlegel, Robert W., Schneider, Udo, Sharma, Sapna, Shi, Lei, Simmons, Adrian J., Siso, Carolina, Smith, Sharon L., Soden, Brian J., Sofieva, Viktoria, Sparks, Tim H., Stackhouse Jr., Paul W., Stauffer, Ryan, Steinbrecht, Wolfgang, Steiner, Andrea K., Stewart, Kenton, Stradiotti, Pietro, Streletskiy, Dimitri A., Telg, Hagen, Thackeray, Stephen J., Thibert, Emmanuel, Todt, Michael, Tokuda, Daisuke, Tourpali, Kleareti, Tye, Mari R., Van der A, Ronald, Schalie, Robin van der, Schrier, Gerard van der, Vliet, Mendy van der, Werf, Guido R. van der, Vliet, Arnold. van, Vernier, Jean-Paul, Vimont, Isaac J., Virts, Katrina, Vivero, Sebastiàn, Vömel, Holger, Vose, Russell S., Wang, Ray H. J., Weber, Markus, Wiese, David, Wild, Jeanette D., Williams, Earle, Wong, Takmeng, Woolway, R. Iestyn, Yin, Xungang, Yuan, Ye, Zhao, Lin, Zhou, Xinjia, Ziemke, Jerry R., Ziese, Markus, and Zotta, Ruxandra M.

Abstract

In 2021, both social and economic activities began to return towards the levels preceding the COVID-19 pandemic for some parts of the globe, with others still experiencing restrictions. Meanwhile, the climate has continued to respond to the ongoing increase in greenhouse gases and resulting warming. La Niña, a phenomenon which tends to depress global temperatures while changing rainfall patterns in many regions, prevailed for all but two months of the year. Despite this, 2021 was one of the six-warmest years on record as measured by global mean surface temperature with an anomaly of between +0.21° and +0.28°C above the 1991–2020 climatology.

Published
2022

21. Global Climate: STATE OF THE CLIMATE IN 2021

Author

Ades, Melanie, Adler, Robert, Aldred, Freya, Allan, R. P., Anderson, John, Anneville, Orlane, Aono, Yasuyuki, Argüez, Anthony, Arosio, Carlo, Augustine, John A., Azorin-Molina, Cesar, Barichivich, Jonathan, Basu, Aman, Beck, Hylke E., Bellouin, Nicolas, Benedetti, Angela, Blagrave, Kevin, Blenkinsop, Stephen, Bock, Olivier, Bodin, Xavier, Bosilovich, Michael G., Boucher, Olivier, Bove, Gerald, Buechler, Dennis, Buehler, Stefan A., Carrea, Laura, Chang, Kai Lan, Christiansen, Hanne H., Christy, John R., Chung, Eui Seok, Ciasto, Laura M., Coldewey-Egbers, Melanie, Cooper, Owen R., Cornes, Richard C., Covey, Curt, Cropper, Thomas, Crotwell, Molly, Cusicanqui, Diego, Davis, Sean M., de Jeu, Richard A.M., Degenstein, Doug, Delaloye, Reynald, Donat, Markus G., Dorigo, Wouter A., Dunn, Robert J.H., Durre, Imke, Dutton, Geoff S., Duveiller, Gregory, Elkins, James W., Estilow, Thomas W., Fedaeff, Nava, Fereday, David, Fioletov, Vitali E., Flemming, Johannes, Foster, Michael J., Frith, Stacey M., Froidevaux, Lucien, Füllekrug, Martin, Garforth, Judith, Garg, Jay, Gentry, Matthew, Gobron, Nadine, Goodman, Steven, Gou, Qiqi, Granin, Nikolay, Guglielmin, Mauro, Hahn, Sebastian, Haimberger, Leopold, Hall, Brad D., Harris, Ian, Hemming, Debbie L., Hirschi, Martin, Ho, Shu Pen, Holzworth, Robert, Hrbáček, Filip, Hubert, Daan, Hulsman, Petra, Hurst, Dale F., Inness, Antje, Isaksen, Ketil, John, Viju O., Jones, Philip D., Junod, Robert, Kääb, Andreas, Kaiser, Johannes W., Kaufmann, Viktor, Kellerer-Pirklbauer, Andreas, Kent, Elizabeth C., Kidd, Richard, Kim, Hyungiun, Kipling, Zak, Koppa, Akash, L'Abée-Lund, Jan Henning, Lan, Xin, Lantz, Kathleen O., Lavers, David, Loeb, Norman G., Loyola, Diego, Madelon, Remi, Malmquist, Hilmar J., Marszelewski, Wlodzimierz, Mayer, Michael, McCabe, Matthew F., McVicar, Tim R., Mears, Carl A., Menzel, Annette, Merchant, Christopher J., Miller, John B., Miralles, Diego G., Montzka, Stephen A., Morice, Colin, Mösinger, Leander, Mühle, Jens, Nicolas, Julien P., Noetzli, Jeannette, Nõges, Tiina, Noll, Ben, O'Keefe, John, Osborn, Tim J., Park, Taejin, Pellet, Cecile, Pelto, Maury S., Perkins-Kirkpatrick, Sarah E., Phillips, Coda, Po-Chedley, Stephen, Polvani, Lorenzo, Preimesberger, Wolfgang, Price, Colin, Pulkkanen, Merja, Rains, Dominik G., Randel, William J., Rémy, Samuel, Ricciardulli, Lucrezia, Richardson, Andrew D., Robinson, David A., Rodell, Matthew, Rodríguez-Fernández, Nemesio J., Rosenlof, Karen H., Roth, Chris, Rozanov, Alexei, Rutishäuser, This, Sánchez-Lugo, Ahira, Sawaengphokhai, Parnchai, Schenzinger, Verena, Schlegel, Robert W., Schneider, Udo, Sharma, Sapna, Shi, Lei, Simmons, Adrian J., Siso, Carolina, Smith, Sharon L., Soden, Brian J., Sofieva, Viktoria, Sparks, Tim H., Stackhouse, Paul W., Stauffer, Ryan, Steinbrecht, Wolfgang, Steiner, Andrea K., Stewart, Kenton, Stradiotti, Pietro, Streletskiy, Dimitri A., Telg, Hagen, Thackeray, Stephen J., Thibert, Emmanuel, Todt, Michael, Tokuda, Daisuke, Tourpali, Kleareti, Tye, Mari R., Van Der, A. Ronald, van der Schalie, Robin, van der Schrier, Gerard, van der Vliet, Mendy, van der Werf, Guido R., van Vliet, Arnold, Vernier, Jean Paul, Vimont, Isaac J., Virts, Katrina, Vivero, Sebastiàn, Vömel, Holger, Vose, Russell S., Wang, Ray H.J., Weber, Markus, Wiese, David, Wild, Jeanette D., Willett, Kate M., Williams, Earle, Wong, Takmeng, Woolway, R. I., Yin, Xungang, Yuan, Ye, Zhao, Lin, Zhou, Xinjia, Ziemke, Jerry R., Ziese, Markus, Zotta, Ruxandra M., Allen, Jessicca, Camper, Amy, Hammer, Gregory, Love-Brotak, S. Elizabeth, Misch, Deborah J., Ohlmann, Laura, Riddle, Deborah B., Veasey, Sara W., Ades, Melanie, Adler, Robert, Aldred, Freya, Allan, R. P., Anderson, John, Anneville, Orlane, Aono, Yasuyuki, Argüez, Anthony, Arosio, Carlo, Augustine, John A., Azorin-Molina, Cesar, Barichivich, Jonathan, Basu, Aman, Beck, Hylke E., Bellouin, Nicolas, Benedetti, Angela, Blagrave, Kevin, Blenkinsop, Stephen, Bock, Olivier, Bodin, Xavier, Bosilovich, Michael G., Boucher, Olivier, Bove, Gerald, Buechler, Dennis, Buehler, Stefan A., Carrea, Laura, Chang, Kai Lan, Christiansen, Hanne H., Christy, John R., Chung, Eui Seok, Ciasto, Laura M., Coldewey-Egbers, Melanie, Cooper, Owen R., Cornes, Richard C., Covey, Curt, Cropper, Thomas, Crotwell, Molly, Cusicanqui, Diego, Davis, Sean M., de Jeu, Richard A.M., Degenstein, Doug, Delaloye, Reynald, Donat, Markus G., Dorigo, Wouter A., Dunn, Robert J.H., Durre, Imke, Dutton, Geoff S., Duveiller, Gregory, Elkins, James W., Estilow, Thomas W., Fedaeff, Nava, Fereday, David, Fioletov, Vitali E., Flemming, Johannes, Foster, Michael J., Frith, Stacey M., Froidevaux, Lucien, Füllekrug, Martin, Garforth, Judith, Garg, Jay, Gentry, Matthew, Gobron, Nadine, Goodman, Steven, Gou, Qiqi, Granin, Nikolay, Guglielmin, Mauro, Hahn, Sebastian, Haimberger, Leopold, Hall, Brad D., Harris, Ian, Hemming, Debbie L., Hirschi, Martin, Ho, Shu Pen, Holzworth, Robert, Hrbáček, Filip, Hubert, Daan, Hulsman, Petra, Hurst, Dale F., Inness, Antje, Isaksen, Ketil, John, Viju O., Jones, Philip D., Junod, Robert, Kääb, Andreas, Kaiser, Johannes W., Kaufmann, Viktor, Kellerer-Pirklbauer, Andreas, Kent, Elizabeth C., Kidd, Richard, Kim, Hyungiun, Kipling, Zak, Koppa, Akash, L'Abée-Lund, Jan Henning, Lan, Xin, Lantz, Kathleen O., Lavers, David, Loeb, Norman G., Loyola, Diego, Madelon, Remi, Malmquist, Hilmar J., Marszelewski, Wlodzimierz, Mayer, Michael, McCabe, Matthew F., McVicar, Tim R., Mears, Carl A., Menzel, Annette, Merchant, Christopher J., Miller, John B., Miralles, Diego G., Montzka, Stephen A., Morice, Colin, Mösinger, Leander, Mühle, Jens, Nicolas, Julien P., Noetzli, Jeannette, Nõges, Tiina, Noll, Ben, O'Keefe, John, Osborn, Tim J., Park, Taejin, Pellet, Cecile, Pelto, Maury S., Perkins-Kirkpatrick, Sarah E., Phillips, Coda, Po-Chedley, Stephen, Polvani, Lorenzo, Preimesberger, Wolfgang, Price, Colin, Pulkkanen, Merja, Rains, Dominik G., Randel, William J., Rémy, Samuel, Ricciardulli, Lucrezia, Richardson, Andrew D., Robinson, David A., Rodell, Matthew, Rodríguez-Fernández, Nemesio J., Rosenlof, Karen H., Roth, Chris, Rozanov, Alexei, Rutishäuser, This, Sánchez-Lugo, Ahira, Sawaengphokhai, Parnchai, Schenzinger, Verena, Schlegel, Robert W., Schneider, Udo, Sharma, Sapna, Shi, Lei, Simmons, Adrian J., Siso, Carolina, Smith, Sharon L., Soden, Brian J., Sofieva, Viktoria, Sparks, Tim H., Stackhouse, Paul W., Stauffer, Ryan, Steinbrecht, Wolfgang, Steiner, Andrea K., Stewart, Kenton, Stradiotti, Pietro, Streletskiy, Dimitri A., Telg, Hagen, Thackeray, Stephen J., Thibert, Emmanuel, Todt, Michael, Tokuda, Daisuke, Tourpali, Kleareti, Tye, Mari R., Van Der, A. Ronald, van der Schalie, Robin, van der Schrier, Gerard, van der Vliet, Mendy, van der Werf, Guido R., van Vliet, Arnold, Vernier, Jean Paul, Vimont, Isaac J., Virts, Katrina, Vivero, Sebastiàn, Vömel, Holger, Vose, Russell S., Wang, Ray H.J., Weber, Markus, Wiese, David, Wild, Jeanette D., Willett, Kate M., Williams, Earle, Wong, Takmeng, Woolway, R. I., Yin, Xungang, Yuan, Ye, Zhao, Lin, Zhou, Xinjia, Ziemke, Jerry R., Ziese, Markus, Zotta, Ruxandra M., Allen, Jessicca, Camper, Amy, Hammer, Gregory, Love-Brotak, S. Elizabeth, Misch, Deborah J., Ohlmann, Laura, Riddle, Deborah B., and Veasey, Sara W.

Published
2022
Full Text
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22. Global Climate

Author

Dunn, Robert J. H., Aldred, Freya, Gobron, Nadine, Miller, John B., Willett, Kate M., Ades, Melanie, Adler, Robert, Allan, R. P., Anderson, John, Anneville, Orlane, Aono, Yasuyuki, Argüez, Anthony, Arosio, Carlo, Augustine, John A., Azorin-Molina, Cesar, Barichivich, Jonathan, Basu, Aman, Beck, Hylke E., Bellouin, Nicolas, Benedetti, Angela, Blagrave, Kevin, Blenkinsop, Stephen, Bock, Olivier, Bodin, Xavier, Bosilovich, Michael G., Boucher, Olivier, Bove, Gerald, Buechler, Dennis, Buehler, Stefan A., Carrea, Laura, Chang, Kai-Lan, Christiansen, Hanne H., Christy, John R., Chung, Eui-Seok, Ciasto, Laura M., Coldewey-Egbers, Melanie, Cooper, Owen R., Cornes, Richard C., Covey, Curt, Cropper, Thomas, Crotwell, Molly, Cusicanqui, Diego, Davis, Sean M., de Jeu, Richard A. M., Degenstein, Doug, Delaloye, Reynald, Donat, Markus G., Dorigo, Wouter A., Durre, Imke, Dutton, Geoff S., Duveiller, Gregory, Elkins, James W., Estilow, Thomas W., Fedaeff, Nava, Fereday, David, Fioletov, Vitali E., Flemming, Johannes, Foster, Michael J., Frith, Stacey M., Froidevaux, Lucien, Füllekrug, Martin, Garforth, Judith, Garg, Jay, Gentry, Matthew, Goodman, Steven, Gou, Qiqi, Granin, Nikolay, Guglielmin, Mauro, Hahn, Sebastian, Haimberger, Leopold, Hall, Brad D., Harris, Ian, Hemming, Debbie L., Hirschi, Martin, Ho, Shu-pen (Ben), Holzworth, Robert, Hrbáček, Filip, Hubert, Daan, Hulsman, Petra, Hurst, Dale F., Inness, Antje, Isaksen, Ketil, John, Viju O., Jones, Philip D., Junod, Robert, Kääb, Andreas, Kaiser, Johannes W., Kaufmann, Viktor, Kellerer-Pirklbauer, Andreas, Kent, Elizabeth C., Kidd, Richard, Kim, Hyungiun, Kipling, Zak, Koppa, Akash, L’Abée-Lund, Jan Henning, Lan, Xin, Lantz, Kathleen O., Lavers, David, Loeb, Norman G., Loyola, Diego, Madelon, Remi, Malmquist, Hilmar J., Marszelewski, Wlodzimierz, Mayer, Michael, McCabe, Matthew F., McVicar, Tim R., Mears, Carl A., Menzel, Annette, Merchant, Christopher J., Miralles, Diego G., Montzka, Stephen A., Morice, Colin, Mösinger, Leander, Mühle, Jens, Nicolas, Julien P., Noetzli, Jeannette, Nõges, Tiina, Noll, Ben, O’Keefe, John, Osborn, Tim J., Park, Taejin, Pellet, Cecile, Pelto, Maury S., Perkins-Kirkpatrick, Sarah E., Phillips, Coda, Po-Chedley, Stephen, Polvani, Lorenzo, Preimesberger, Wolfgang, Price, Colin, Pulkkanen, Merja, Rains, Dominik G., Randel, William J., Rémy, Samuel, Ricciardulli, Lucrezia, Richardson, Andrew D., Robinson, David A., Rodell, Matthew, Rodríguez-Fernández, Nemesio J., Rosenlof, Karen H., Roth, Chris, Rozanov, Alexei, Rutishäuser, This, Sánchez-Lugo, Ahira, Sawaengphokhai, Parnchai, Schenzinger, Verena, Schlegel, Robert W., Schneider, Udo, Sharma, Sapna, Shi, Lei, Simmons, Adrian J., Siso, Carolina, Smith, Sharon L., Soden, Brian J., Sofieva, Viktoria, Sparks, Tim H., Stackhouse, Paul W., Stauffer, Ryan, Steinbrecht, Wolfgang, Steiner, Andrea K., Stewart, Kenton, Stradiotti, Pietro, Streletskiy, Dimitri A., Telg, Hagen, Thackeray, Stephen J., Thibert, Emmanuel, Todt, Michael, Tokuda, Daisuke, Tourpali, Kleareti, Tye, Mari R., van der A, Ronald, van der Schalie, Robin, van der Schrier, Gerard, van der Vliet, Mendy, van der Werf, Guido R., van Vliet, Arnold., Vernier, Jean-Paul, Vimont, Isaac J., Virts, Katrina, Vivero, Sebastiàn, Vömel, Holger, Vose, Russell S., Wang, Ray H. J., Weber, Markus, Wiese, David, Wild, Jeanette D., Williams, Earle, Wong, Takmeng, Woolway, R. I., Yin, Xungang, Yuan, Ye, Zhao, Lin, Zhou, Xinjia, Ziemke, Jerry R., Ziese, Markus, Zotta, Ruxandra M., Dunn, Robert J. H., Aldred, Freya, Gobron, Nadine, Miller, John B., Willett, Kate M., Ades, Melanie, Adler, Robert, Allan, R. P., Anderson, John, Anneville, Orlane, Aono, Yasuyuki, Argüez, Anthony, Arosio, Carlo, Augustine, John A., Azorin-Molina, Cesar, Barichivich, Jonathan, Basu, Aman, Beck, Hylke E., Bellouin, Nicolas, Benedetti, Angela, Blagrave, Kevin, Blenkinsop, Stephen, Bock, Olivier, Bodin, Xavier, Bosilovich, Michael G., Boucher, Olivier, Bove, Gerald, Buechler, Dennis, Buehler, Stefan A., Carrea, Laura, Chang, Kai-Lan, Christiansen, Hanne H., Christy, John R., Chung, Eui-Seok, Ciasto, Laura M., Coldewey-Egbers, Melanie, Cooper, Owen R., Cornes, Richard C., Covey, Curt, Cropper, Thomas, Crotwell, Molly, Cusicanqui, Diego, Davis, Sean M., de Jeu, Richard A. M., Degenstein, Doug, Delaloye, Reynald, Donat, Markus G., Dorigo, Wouter A., Durre, Imke, Dutton, Geoff S., Duveiller, Gregory, Elkins, James W., Estilow, Thomas W., Fedaeff, Nava, Fereday, David, Fioletov, Vitali E., Flemming, Johannes, Foster, Michael J., Frith, Stacey M., Froidevaux, Lucien, Füllekrug, Martin, Garforth, Judith, Garg, Jay, Gentry, Matthew, Goodman, Steven, Gou, Qiqi, Granin, Nikolay, Guglielmin, Mauro, Hahn, Sebastian, Haimberger, Leopold, Hall, Brad D., Harris, Ian, Hemming, Debbie L., Hirschi, Martin, Ho, Shu-pen (Ben), Holzworth, Robert, Hrbáček, Filip, Hubert, Daan, Hulsman, Petra, Hurst, Dale F., Inness, Antje, Isaksen, Ketil, John, Viju O., Jones, Philip D., Junod, Robert, Kääb, Andreas, Kaiser, Johannes W., Kaufmann, Viktor, Kellerer-Pirklbauer, Andreas, Kent, Elizabeth C., Kidd, Richard, Kim, Hyungiun, Kipling, Zak, Koppa, Akash, L’Abée-Lund, Jan Henning, Lan, Xin, Lantz, Kathleen O., Lavers, David, Loeb, Norman G., Loyola, Diego, Madelon, Remi, Malmquist, Hilmar J., Marszelewski, Wlodzimierz, Mayer, Michael, McCabe, Matthew F., McVicar, Tim R., Mears, Carl A., Menzel, Annette, Merchant, Christopher J., Miralles, Diego G., Montzka, Stephen A., Morice, Colin, Mösinger, Leander, Mühle, Jens, Nicolas, Julien P., Noetzli, Jeannette, Nõges, Tiina, Noll, Ben, O’Keefe, John, Osborn, Tim J., Park, Taejin, Pellet, Cecile, Pelto, Maury S., Perkins-Kirkpatrick, Sarah E., Phillips, Coda, Po-Chedley, Stephen, Polvani, Lorenzo, Preimesberger, Wolfgang, Price, Colin, Pulkkanen, Merja, Rains, Dominik G., Randel, William J., Rémy, Samuel, Ricciardulli, Lucrezia, Richardson, Andrew D., Robinson, David A., Rodell, Matthew, Rodríguez-Fernández, Nemesio J., Rosenlof, Karen H., Roth, Chris, Rozanov, Alexei, Rutishäuser, This, Sánchez-Lugo, Ahira, Sawaengphokhai, Parnchai, Schenzinger, Verena, Schlegel, Robert W., Schneider, Udo, Sharma, Sapna, Shi, Lei, Simmons, Adrian J., Siso, Carolina, Smith, Sharon L., Soden, Brian J., Sofieva, Viktoria, Sparks, Tim H., Stackhouse, Paul W., Stauffer, Ryan, Steinbrecht, Wolfgang, Steiner, Andrea K., Stewart, Kenton, Stradiotti, Pietro, Streletskiy, Dimitri A., Telg, Hagen, Thackeray, Stephen J., Thibert, Emmanuel, Todt, Michael, Tokuda, Daisuke, Tourpali, Kleareti, Tye, Mari R., van der A, Ronald, van der Schalie, Robin, van der Schrier, Gerard, van der Vliet, Mendy, van der Werf, Guido R., van Vliet, Arnold., Vernier, Jean-Paul, Vimont, Isaac J., Virts, Katrina, Vivero, Sebastiàn, Vömel, Holger, Vose, Russell S., Wang, Ray H. J., Weber, Markus, Wiese, David, Wild, Jeanette D., Williams, Earle, Wong, Takmeng, Woolway, R. I., Yin, Xungang, Yuan, Ye, Zhao, Lin, Zhou, Xinjia, Ziemke, Jerry R., Ziese, Markus, and Zotta, Ruxandra M.

Abstract

In 2021, both social and economic activities began to return towards the levels preceding the COVID-19 pandemic for some parts of the globe, with others still experiencing restrictions. Meanwhile, the climate has continued to respond to the ongoing increase in greenhouse gases and resulting warming. La Niña, a phenomenon which tends to depress global temperatures while changing rainfall patterns in many regions, prevailed for all but two months of the year. Despite this, 2021 was one of the six-warmest years on record as measured by global mean surface temperature with an anomaly of between +0.21° and +0.28°C above the 1991–2020 climatology. Lake surface temperatures were their highest on record during 2021. The number of warm days over land also reached a new record high. Exceptional heat waves struck the Pacific Coast of North America, leading to a new Canadian maximum temperature of 49.6°C at Lytton, British Columbia, on 29 June, breaking the previous national record by over 4°C. In Death Valley, California, the peak temperature reached 54.4°C on 9 July, equaling the temperature measured in 2020, and the highest temperature recorded anywhere on the globe since at least the 1930s. Over the Mediterranean, a provisional new European record of 48.8°C was set in Sicily on 11 August. In the atmosphere, the annual mean tropospheric temperature was among the 10 highest on record, while the stratosphere continued to cool. While La Niña was present except for June and July, likely influencing Australia’s coolest year since 2012 and wettest since 2016, other modes of variability played important roles. A negative Indian Ocean dipole event became established during July, associated with a warmer east and cooler west Indian Ocean. Northern Hemisphere winters were affected by a negative phase of the North Atlantic Oscillation at both the beginning and end of 2021. In the Southern Hemisphere, a very strong positive Southern Annular Mode (also known as the Antarctic Oscillation)

Published
2022

31. Diagram Processing Procedures.

Author

Maury, S.

Abstract

Examines problem-solving techniques used by students in French schools by testing 370 children in grades 6-9. Finds a high degree of variability in procedure selection among those tested. Results show the ability to use a standard procedure is sufficient for solving test problems. Recommends stressing cognitive flexibility. (NL)

Published
1990

34. Global Climate

Author

Dunn, Robert J. H., primary, Aldred, F., additional, Gobron, Nadine, additional, Miller, John B., additional, Willett, Kate M., additional, Ades, M., additional, Adler, Robert, additional, Allan, Richard, P., additional, Allan, Rob, additional, Anderson, J., additional, Argüez, Anthony, additional, Arosio, C., additional, Augustine, John A., additional, Azorin-Molina, C., additional, Barichivich, J., additional, Beck, H. E., additional, Becker, Andreas, additional, Bellouin, Nicolas, additional, Benedetti, Angela, additional, Berry, David I., additional, Blenkinsop, Stephen, additional, Bock, Olivier, additional, Bodin, X., additional, Bosilovich, Michael G., additional, Boucher, Olivier, additional, Buehler, S. A., additional, Calmettes, B., additional, Carrea, Laura, additional, Castia, Laura, additional, Christiansen, Hanne H., additional, Christy, John R., additional, Chung, E.-S., additional, Coldewey-Egbers, Melanie, additional, Cooper, Owen R., additional, Cornes, Richard C., additional, Covey, Curt, additional, Cretaux, J.-F., additional, Crotwell, M., additional, Davis, Sean M., additional, de Jeu, Richard A. M., additional, Degenstein, Doug, additional, Delaloye, R., additional, Di Girolamo, Larry, additional, Donat, Markus G., additional, Dorigo, Wouter A., additional, Durre, Imke, additional, Dutton, Geoff S., additional, Duveiller, Gregory, additional, Elkins, James W., additional, Fioletov, Vitali E., additional, Flemming, Johannes, additional, Foster, Michael J., additional, Frith, Stacey M., additional, Froidevaux, Lucien, additional, Garforth, J., additional, Gentry, Matthew, additional, Gupta, S. K., additional, Hahn, S., additional, Haimberger, Leopold, additional, Hall, Brad D., additional, Harris, Ian, additional, Hemming, D. L., additional, Hirschi, M., additional, Ho, Shu-pen (Ben), additional, Hrbacek, F., additional, Hubert, Daan, additional, Hurst, Dale F., additional, Inness, Antje, additional, Isaksen, K., additional, John, Viju O., additional, Jones, Philip D., additional, Junod, Robert, additional, Kaiser, J. W., additional, Kaufmann, V., additional, Kellerer-Pirklbauer, A., additional, Kent, Elizabeth C., additional, Kidd, R., additional, Kim, Hyungjun, additional, Kipling, Z., additional, Koppa, A., additional, Kraemer, B. M., additional, Kratz, D. P., additional, Lan, Xin, additional, Lantz, Kathleen O., additional, Lavers, D., additional, Loeb, Norman G., additional, Loyola, Diego, additional, Madelon, R., additional, Mayer, Michael, additional, McCabe, M. F., additional, McVicar, Tim R., additional, Mears, Carl A., additional, Merchant, Christopher J., additional, Miralles, Diego G., additional, Moesinger, L., additional, Montzka, Stephen A., additional, Morice, Colin, additional, Mösinger, L., additional, Mühle, Jens, additional, Nicolas, Julien P., additional, Noetzli, Jeannette, additional, Noll, Ben, additional, O’Keefe, J., additional, Osborn, Tim J., additional, Park, T., additional, Pasik, A. J., additional, Pellet, C., additional, Pelto, Maury S., additional, Perkins-Kirkpatrick, S. E., additional, Petron, G., additional, Phillips, Coda, additional, Po-Chedley, S., additional, Polvani, L., additional, Preimesberger, W., additional, Rains, D. G., additional, Randel, W. J., additional, Rayner, Nick A., additional, Rémy, Samuel, additional, Ricciardulli, L., additional, Richardson, A. D., additional, Robinson, David A., additional, Rodell, Matthew, additional, Rodríguez-Fernández, N. J., additional, Rosenlof, K.H., additional, Roth, C., additional, Rozanov, A., additional, Rutishäuser, T., additional, Sánchez-Lugo, Ahira, additional, Sawaengphokhai, P., additional, Scanlon, T., additional, Schenzinger, Verena, additional, Schlegel, R. W., additional, Sharma, S., additional, Shi, Lei, additional, Simmons, Adrian J., additional, Siso, Carolina, additional, Smith, Sharon L., additional, Soden, B. J., additional, Sofieva, Viktoria, additional, Sparks, T. H., additional, Stackhouse, Paul W., additional, Steinbrecht, Wolfgang, additional, Stengel, Martin, additional, Streletskiy, Dimitri A., additional, Sun-Mack, Sunny, additional, Tans, P., additional, Thackeray, S. J., additional, Thibert, E., additional, Tokuda, D., additional, Tourpali, Kleareti, additional, Tye, Mari R., additional, van der A, Ronald, additional, van der Schalie, Robin, additional, van der Schrier, Gerard, additional, van der Vliet, M., additional, van der Werf, Guido R., additional, Vance, A., additional, Vernier, Jean-Paul, additional, Vimont, Isaac J., additional, Vömel, Holger, additional, Vose, Russell S., additional, Wang, Ray, additional, Weber, Markus, additional, Wiese, David, additional, Wilber, Anne C., additional, Wild, Jeanette D., additional, Wong, Takmeng, additional, Woolway, R. Iestyn, additional, Zhou, Xinjia, additional, Yin, Xungang, additional, Zhao, Guangyu, additional, Zhao, Lin, additional, Ziemke, Jerry R., additional, Ziese, Markus, additional, and Zotta, R. M., additional

Published
2021
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35. Development of the Fischer-Tropsch Process: From the Reaction Concept to the Process Book

Author

Boyer C., Gazarian J., Lecocq V., Maury S., Forret A., Schweitzer J.M., and Souchon V.

Subjects
Chemical technology, TP1-1185, Energy industries. Energy policy. Fuel trade, HD9502-9502.5
Abstract

The process development by IFP Energies nouvelles (IFPEN)/ENI/Axens of a Fischer-Tropsch process is described. This development is based on upstream process studies to choose the process scheme, reactor technology and operating conditions, and downstream to summarize all development work in a process guide. A large amount of work was devoted to the catalyst performances on one hand and the scale-up of the slurry bubble reactor with dedicated complementary tools on the other hand. Finally, an original approach was implemented to validate both the process and catalyst on an industrial scale by combining a 20 bpd unit in ENI’s Sannazzaro refinery, with cold mock-ups equivalent to 20 and 1 000 bpd at IFPEN and a special “Large Validation Tool” (LVT) which reproduces the combined effect of chemical reaction condition stress and mechanical stress equivalent to a 15 000 bpd industrial unit. Dedicated analytical techniques and a dedicated model were developed to simulate the whole process (reactor and separation train), integrating a high level of complexity and phenomena coupling to scale-up the process in a robust reliable base on an industrial scale.

Published
2016
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36. Electron Paramagnetic Resonance Study of the Fractions and Trapped Compounds in Asphaltenes of Merey Heavy Crude Oils and Its Vacuum Residue

Author

Maury S. Hernández and Pedro Silva

Subjects
Chemistry, General Chemical Engineering, Analytical chemistry, Asphaltenes, Energy Engineering and Power Technology, 02 engineering and technology, purl.org/becyt/ford/1.3 [https], Crude Oils, 021001 nanoscience & nanotechnology, Crude oil, law.invention, purl.org/becyt/ford/1 [https], Residue (chemistry), Fuel Technology, 020401 chemical engineering, law, purl.org/becyt/ford/1.4 [https], Fractions, EPR, 0204 chemical engineering, 0210 nano-technology, Electron paramagnetic resonance, Asphaltene, Trapped Compounds
Abstract

The electron paramagnetic resonance (EPR) technique was used to study the behavior of the asphaltenes from the Merey crude oil (ASCM), its vacuum residue (ARVM), its fractions, and trapped compounds (A1-ASCM, A2-ASCM, TC-ASCM, A1-ARVM, A2-ARVM, and TC-ARVM). Asphaltenes were precipitated from Merey heavy crude oil and its vacuum residue. The fractionation of our petroleum asphaltenes was carried out using the para-nitrophenol (PNP) method. Two fractions named A1 and A2 and trapped compounds were obtained. The temperature dependence of the EPR spectra was used to obtain a set of temperatures related to free radical (FR) generation and recombination. From the analysis of the EPR spectrum of the most intense signal of the vanadium, we obtain the temperature ranges of the anisotropic-to-isotropic domains, we found a nonlinear behavior of the B parameter in the temperature range studied, and we propose a functional relationship for this parameter as a function of the temperature. On the other hand, we found the temperatures for the slow-to-fast motion regime in these samples and correlated it with the mobility of the fractions. Fil: Hernandez Nuñez, Maury Sabrina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Industrias. Instituto de Tecnología de Alimentos y Procesos Químicos. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Tecnología de Alimentos y Procesos Químicos; Argentina Fil: Silva, Pedro J.. Instituto Venezolano de Investigaciones Científicas; Venezuela

Published
2020
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37. High-dose imatinib mesylate combined with vincristine and dexamethasone (DIV regimen) as induction therapy in patients with resistant Philadelphia-positive acute lymphoblastic leukemia and lymphoid blast crisis of chronic myeloid leukemia

Author

Rea, D, Legros, L, Raffoux, E, Thomas, X, Turlure, P, Maury, S, Dupriez, B, Pigneux, A, Choufi, B, Reman, O, Stéphane, D, Royer, B, Vigier, M, Ojeda-Uribe, M, Recher, C, Dombret, H, Huguet, F, and Rousselot, P

Published
2006
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42. Post remission consolidation by autologous HCT for AML in CR1, negative implications for subsequent allogeneic HCT in CR2. A Study by the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT)

Author

Passweg, J R, Labopin, M, Christopeit, M, Cornelissen, J, Pabst, Thomas, Socié, G, Russel, N, Yakoub-Agha, I, Blaise, D, Gedde-Dahl, T, Labussière-Wallet, H, Malladi, R, Forcade, E, Maury, S, Polge, E, Lanza, F, Gorin, N C, Mohty, M, and Nagler, A

Subjects
surgical procedures, operative, immune system diseases, hemic and lymphatic diseases, 610 Medicine & health
Abstract

After autologous hematopoetic cell transplantation, (HCT in 1st complete remission (CR1), patients with acute myeloid leukemia (AML) may relapse and undergo allogeneic HCT in CR2. The aim of this study was to analyze outcome of allogeneic HCT performed in CR2 comparing patients with prior consolidation by autologous HCT vs. patients with chemotherapy consolidation. Included were 2619 adults, with allogeneic HCT in CR2, in 2000-2017 with (n=417) or without (n=2202) prior autologous HCT. Patient groups were not entirely comparable; patients with prior autologous HCT were younger, had less often a favorable cytogenetic profile, had more commonly donors other than matched siblings and more often received reduced intensity conditioning (RIC) conditioning. In multivariate analysis non relapse mortality (NRM) risks in patients with prior autologous HCT were 1.34 (1.07-1.67), p=0.01 after adjustment for age, cytogenetic risk, transplant year, donor, conditioning intensity, sex matching, interval diagnosis-relapse and relapse-allogeneic HCT as compared to chemotherapy consolidation. Similarly, risks of events in leukemia free survival and graft versus host disease, relapse free survival were higher with prior autologous HCT, 1.17 (1.01-1.35), p=0.03 and 1.18 (1.03-1.35) p= 0.02, respectively. Risk of death was also higher 1.13 (0.97-1.32) p=0.1 but this was not significant. Post remission consolidation with autologous HCT for AML in CR1 increases toxicity of subsequent allogeneic HCT in CR2.

Published
2020
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43. Temperature Dependence of the Electron Paramagnetic Resonance Spectrum of Asphaltenes from Venezuelan Crude Oils and Their Vacuum Residues

Author

Maury S. Hernández, Pedro Silva, and David Santiago Coll

Subjects
Materials science, General Chemical Engineering, Radical, Ciencias Físicas, Analytical chemistry, Asphaltenes, Energy Engineering and Power Technology, Vanadium, chemistry.chemical_element, 02 engineering and technology, Otras Ciencias Físicas, Spectral line, law.invention, purl.org/becyt/ford/1 [https], chemistry.chemical_compound, 020401 chemical engineering, Curie-Weiss like temperatures, law, purl.org/becyt/ford/1.4 [https], 0204 chemical engineering, Electron paramagnetic resonance, Multiplet, Conformational isomerism, Asphaltene, Otras Ciencias Químicas, Ciencias Químicas, purl.org/becyt/ford/1.3 [https], 021001 nanoscience & nanotechnology, Porphyrin, Electron Paramagnetic Resonance, Fuel Technology, chemistry, 0210 nano-technology, CIENCIAS NATURALES Y EXACTAS
Abstract

The electron paramagnetic resonance (EPR) technique is used to evaluate the temperature dependence of the aggregation processes in asphaltenes of heavy and extra-heavy crude oils and their vacuum residues from the Venezuelan Oil Belt. All of the EPR spectra of the samples studied show an intense central signal assigned to free radicals (FRs) and a multiplet as a result of the presence of a V+ 4 porphyrin. From the analyses of the inverse of the normalized area as a function of the temperature for the FR signal and the most intense peak in the vanadium multiplet, we obtain a set of temperatures related to the transition of fast-to-slow motion regions, the temperature of generation-recombination of FRs, and the cracking temperature in all of the samples. On the other hand, applying a Curie-Weiss law, we obtain the order-disorder temperatures and correlated them with the American Petroleum Institute grade of the samples. A computational simulation was performed to propose possible conformers based on the experimental data to confirm our results, which can be used as a probe of the structural and conformational changes in the asphaltene structure. Fil: Hernandez Nuñez, Maury Sabrina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentina Fil: Coll, David S.. Instituto Venezolano de Investigaciones Científicas; Venezuela Fil: Silva, Pedro J.. Instituto Venezolano de Investigaciones Científicas; Venezuela

Published
2019
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44. Judicial ethics and simulation based training.

Author

Simon, Stephen M. and Landsman, Maury S.

Subjects
University of Minnesota. Law School -- Curricula, Judicial ethics -- Study and teaching, Law schools -- Curricula, Simulation games in education -- Usage
Abstract

The Judicial Ethics Education Project at the University of Minnesota Law School is part of the Minnesota Judicial Trial Skills Training Program and uses case simulations to show ethical and management problems needing immediate attention during a trial. Although simulation is effective according to the literature and empirical data, using the technique to teach judicial ethics has some problems. A program using the technique to train judges on the ethical problems in ex parte communication, political activity, demeanor and bias is reported on. This program received much positive anecdotal response and could be redone to fit other jurisdictions.

Published
1995

45. Folivory elicits a strong defense reaction in Catharanthus roseus: metabolomic and transcriptomic analyses reveal distinct local and systemic responses

Author

de Bernonville, T., Carqueijeiro, I., Lanoue, A., Lafontaine, F., Bel, P., Liesecke, F., Musset, K., Oudin, A., Glevarec, G., Pichon, O., Besseau, S., Clastre, M., St-Pierre, B., Flors, V., Maury, S., Huguet, E., O'Connor, S., Courdavault, V., Biomolécules et biotechnologies végétales (BBV EA 2106), Université de Tours, Dept CAMN, Plant Physiol Sect, Metab Integrat & Cell Signaling Grp, Universitat Jaume I, Institut de recherche sur la biologie de l'insecte UMR7261 (IRBI), Université de Tours-Centre National de la Recherche Scientifique (CNRS), Université Francois Rabelais [Tours], Laboratoire de Biologie des Ligneux et des Grandes Cultures (LBLGC), Institut National de la Recherche Agronomique (INRA)-Université d'Orléans (UO), Centre National de la Recherche Scientifique (CNRS), Department of Biological Chemistry, Weizmann Institute of Science, Université de Tours (UT), Université de Tours (UT)-Centre National de la Recherche Scientifique (CNRS), and Weizmann Institute of Science [Rehovot, Israël]

Subjects
Transcription, Genetic, endocrine system diseases, periwinkle (plant), approche transcriptomique, Catharanthus, monoterpène, interaction plante insecte, Cyclopentanes, alcaloide indolique, Models, Biological, Article, Indole Alkaloids, catharanthus roseus, manduca sexta, Gene Expression Regulation, Plant, Manduca, Animals, Metabolomics, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, Herbivory, Oxylipins, RNA, Messenger, Photosynthesis, Plant Proteins, secondary metabolism, Vegetal Biology, Gene Expression Profiling, fungi, métabolisme secondaire, plant insect interaction, Biosynthetic Pathways, Plant Leaves, Larva, Monoterpenes, Secondary metabolism, Plant sciences, Biologie végétale
Abstract

Plants deploy distinct secondary metabolisms to cope with environment pressure and to face bio-aggressors notably through the production of biologically active alkaloids. This metabolism-type is particularly elaborated in Catharanthus roseus that synthesizes more than a hundred different monoterpene indole alkaloids (MIAs). While the characterization of their biosynthetic pathway now reaches completion, still little is known about the role of MIAs during biotic attacks. As a consequence, we developed a new plant/herbivore interaction system by challenging C. roseus leaves with Manduca sexta larvae. Transcriptomic and metabolic analyses demonstrated that C. roseus respond to folivory by both local and systemic processes relying on the activation of specific gene sets and biosynthesis of distinct MIAs following jasmonate production. While a huge local accumulation of strictosidine was monitored in attacked leaves that could repel caterpillars through its protein reticulation properties, newly developed leaves displayed an increased biosynthesis of the toxic strictosidine-derived MIAs, vindoline and catharanthine, produced by up-regulation of MIA biosynthetic genes. In this context, leaf consumption resulted in a rapid death of caterpillars that could be linked to the MIA dimerization observed in intestinal tracts. Furthermore, this study also highlights the overall transcriptomic control of the plant defense processes occurring during herbivory. We gratefully acknowledge the financial support from the “Région Centre” (France, ABISAL grant) and from the University of Tours.

Published
2017
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46. Unrelated alternative donor transplantation for severe acquired aplastic anemia: a study from the French Society of Bone Marrow Transplantation and Cell Therapies and the Severe Aplastic Anemia Working Party of EBMT

Author

Devillier, R., Dalle, J.-H., Kulasekararaj, A., D'Aveni, Maud, Daveni, M., Clement, L., Chybicka, A., Vigouroux, S., Chevallier, P., Koh, M., Bertrand, Y., Michallet, M., Zecca, M., Yakoub-Agha, I., Cahn, J.-Y., Ljungman, P., Bernard, M., Loiseau, P., Dubois, V., Maury, S., Socie, G., Dufour, C., de Latour, R., Hôpital Robert Debré Paris, Hôpital Robert Debré, Centre hospitalier universitaire de Nantes (CHU Nantes), Service d'hématologie [Hôpital Edouard Herriot - HCL], Hôpital Edouard Herriot [CHU - HCL], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), CHU Pontchaillou [Rennes], Milieux aquatiques, écologie et pollutions (UR MALY), Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), and Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Adult, Male, medicine.medical_specialty, Allogeneic transplantation, Transplantation Conditioning, Adolescent, Anemia, [SDV]Life Sciences [q-bio], Graft vs Host Disease, Severity of Illness Index, Lymphocyte Depletion, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Internal medicine, Severity of illness, Medicine, Humans, Transplantation, Homologous, Child, Survival analysis, ComputingMilieux_MISCELLANEOUS, Aged, Bone Marrow Transplantation, business.industry, Hazard ratio, Anemia, Aplastic, Infant, Hematology, Articles, Middle Aged, medicine.disease, Prognosis, Survival Analysis, 3. Good health, Surgery, Transplantation, Treatment Outcome, 030220 oncology & carcinogenesis, Child, Preschool, Cohort, Female, France, business, Unrelated Donors, 030215 immunology
Abstract

Unrelated allogeneic transplantation for severe aplastic anemia is a treatment option after immunosuppressive treatment failure in the absence of a matched sibling donor. Age, delay between disease diagnosis and transplantation, and HLA matching are the key factors in transplantation decisions, but their combined impact on patient outcomes remains unclear. Using the French Society of Bone Marrow Transplantation and Cell Therapies registry, we analyzed all consecutive patients (n=139) who underwent a first allogeneic transplantation for idiopathic severe aplastic anemia from an unrelated donor between 2000 and 2012. In an adjusted multivariate model, age over 30 years (Hazard Ratio=2.39; P=0.011), time from diagnosis to transplantation over 12 months (Hazard Ratio=2.18; P=0.027) and the use of a 9/10 mismatched unrelated donor (Hazard Ratio=2.14; P=0.036) were independent risk factors that significantly worsened overall survival. Accordingly, we built a predictive score using these three parameters, considering patients at low (zero or one risk factors, n=94) or high (two or three risk factors, n=45) risk. High-risk patients had significantly shorter survival (Hazard Ratio=3.04; P

Published
2016
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47. UTILIZACIÓN DE SUPLEMENTOS NUTRICIONALES PARA EL MANEJO DEL SOBREPESO Y OBESIDAD: UNA REVISIÓN DE LA EVIDENCIA

Author

Eduard Maury S, Erika Ochoa O, Martin Gotteland, and Alejandra Wiedeman M

Subjects
suplementos nutricionales, Nutrition and Dietetics, sobrepeso, obesidad, Food Science
Abstract

Paralelamente al rápido aumento de la prevalencia de sobrepeso y obesidad han surgido en el mercado múltiples productos que prometen estimular la pérdida de peso sin modificar la dieta y estilo de vida de los individuos. El objetivo de este trabajo es evaluar la evidencia científica que apoye el uso de tres productos disponibles en Chile para el control ponderal y la reducción de sobrepeso y obesidad: una emulsión lipídica que estimula el freno ileal, un inhibidor de proteasa y un inhibidor de amilasa. Los resultados indican que el inhibidor de amilasa y el inhibidor de proteasa, si bien parecen funcionar in vitro, no muestran ningún efecto sobre el control ponderal en los ensayos clínicos realizados tanto en sujetos normopeso como en obesos. El nivel de evidencia que apoya el uso de estos productos para el control ponderal es por lo tanto insuficiente. En caso de la emulsión lipídica, los resultados son conflictivos y más estudios son necesarios para confirmar su eventual efecto sobre el control del peso corporal.

Published
2011
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48. Forest tree genomics 10 achievements from the past 10 years and future prospects

Author

Plomion, C., Bastien, C., Bogeat-Triboulot, M. B., Bouffier, L., Déjardin, A., Duplessis, S., Fady, B., Heuertz, M., Le Gac, A. L., Le Provost, G., Legué, V., Lelu-Walter, M. A., Leplé, J. C., Maury, S., Morel, A., Oddou-Muratorio, S., Pilate, G., Sánchez, L., Scotti, I., Scotti-Saintagne, C., Segura, V., Trontin, J. F., and Vacher, C.

Subjects
Breeding and conservation, Foresttrees, Interactome, Developmental biology, Micro-evolution, Epigenetics, Genomics
Abstract

Key message This review highlights some of the discoveries and applications made possible by “omics” technologies over the last 10 years and provides perspectives for pioneering research to increase our understanding of tree biology. Context A decade after the first forest tree genome sequence was released into the public domain, the rapidly evolving genomics and bioinformatics toolbox has advanced our understanding of the structure, functioning, and evolution of forest tree genomes. Aims and methods This review highlights some of the discoveries and applications that “omics” technologies have made possible for forest trees over the past 10 years. Results In this review, we start by our current understanding of genome evolution and intricacies of gene regulation for reproduction, development, and responses to biotic and abiotic stresses. We then skim over advances in interactome analysis and epigenomics, the knowledge of the extent of genetic variation within and between species, revealing micro- and macro-evolutionary processes and species history, together with the complex architecture of quantitative traits. We finally end with applications in genetic resource conservation and breeding. Conclusion The knowledge gained through the use of these technologies has a huge potential impact for adapting forests to the main challenges they will have to face changing demand from ecosystem services with potentially conflicting strategies in terms of conservation and use, as well as climate changes and associated threats. Genomics will undoubtedly play a major role over the next decade and beyond, not only to further understand the mechanisms underlying adaptation and evolution but also to develop and implement innovative management and policy actions to preserve the adaptability of natural forests and intensively managed plantations. © 2015, INRA and Springer-Verlag France.

Published
2016

50. Effects of Land Use and Disturbance on Benthic Insects in Headwater Streams Draining Small Watersheds North of Charlotte, NC

Author

Aaron Spivak, Christopher J. Paradise, and Maury S. Gage

Subjects
geography, geography.geographical_feature_category, Land use, Habitat, Disturbance (ecology), Ecology, Aquatic ecosystem, Aquatic insect, Environmental science, STREAMS, Surface runoff, Ecology, Evolution, Behavior and Systematics, Riparian zone
Abstract

Increasing development north of Charlotte, NC, threatens aquatic life in streams by reducing riparian zones and increasing runoff. Runoff, sedi- mentation from erosion, and poor construction practices are principal sources of pollution. We asked how land use and disturbance affected benthic insects. We visited nine streams from May to October 2001, collected data on insect diver- sity, chemistry, and physical habitat. We used a Geographic Information System to delineate watersheds and land use patterns. Watersheds were categorized based on land use, abiotic variables, and disturbance. Insect communities were more diverse in streams draining low disturbance watersheds than in streams draining highly developed watersheds. Sensitive taxa were found in streams with extensively forested watersheds, but were nonexistent in extensively devel- oped watersheds. Disturbances occurring in streams caused declines in diver- sity, often eliminating sensitive taxa. Aquatic insect diversity is related to land use patterns and disturbances, and anthropogenic alteration of habitat has nega- tive consequences to that diversity.

Published
2004
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