Search

Your search keyword '"Martin-Pelaez S"' showing total 5 results
Start Over Author "Martin-Pelaez S" Search Limiters Available in Library Collection
5 results on '"Martin-Pelaez S"'

1. Intensive Weight-Loss Lifestyle Intervention Using Mediterranean Diet and COVID-19 Risk in Older Adults: Secondary Analysis of PREDIMED-Plus Trial

Author

Shyam, Sangeetha, García-Gavilán, J. F., Paz-Graniel, I., Gaforio, J. J., Martínez-González, M. Á., Corella, D., Martínez, J. A., Alonso-Gómez, Á. M., Wärnberg, J., Vioque, J., Romaguera, D., López-Miranda, J., Estruch, R., Tinahones, F. J., Lapetra, J., Serra-Majem, J. L., Bueno-Cavanillas, A., Tur, J. A., Sánchez, V. Martín, Pintó, X., Matía-Martín, P., Vidal, J., del Mar Alcarria, M., Daimiel, L., Ros, E., Fernandez-Aranda, F., Nishi, S. K., García-Regata, Ó., Araluce, R. Perez, Asensio, E. M., Castañer, O., Garcia-Rios, A., Oncina-Cánovas, A., Bouzas, C., Zulet, M. A., Rayó, E., Casas, R., Martin-Pelaez, S., Tojal-Sierra, L., Bernal-López, M. R., Carlos, S., Sorlí, J. V., Goday, A., Peña-Orihuela, P. J., Pastor-Morel, A., Eguaras, S., Zomeño, M. D., Delgado-Rodríguez, M., Babio, N., Fitó, M., and Salas-Salvadó, Jordi

Published
2023
Full Text
View/download PDF

2. Association of adiposity and its changes over time with COVID-19 risk in older adults with overweight/obesity and metabolic syndrome: a longitudinal evaluation in the PREDIMED-Plus cohort

Author

Universitat Rovira i Virgili, Shyam, S; Garcia-Gavilan, JF; Paz-Graniel, I; Gaforio, JJ; Martinez-Gonzalez, MA; Corella, D; Martinez, JA; Alonso-Gomez, AM; Waernberg, J; Vioque, J; Romaguera, D; Lopez-Miranda, J; Estruch, R; Tinahones, FJ; Lapetra, J; Serra-Majem, JL; Bueno-Cavanillas, A; Tur, JA; Sanchez, VM; Pinto, X; Matia-Martin, P; Vidal, J; Vazquez, C; Daimiel, L; Ros, E; Fernandez-Aranda, F; Nishi, SK; Garcia-Regata, O; Toledo, E; Asensio, EM; Castaner, O; Garcia-Rios, A; Torres-Collado, L; Gomez-Gracia, E; Zulet, MA; Ruiz, NG; Casas, R; Cano-Ibanez, N; Tojal-Sierra, L; Gomez-Perez, AM; Sorli, JV; Cinza-Sanjurjo, S; Martin-Pelaez, S; Pena-Orihuela, PJ; Oncina-Canovas, A; Perez-Araluce, R; Zomeno, MD; Chaplin, A; Delgado-Rodriguez, M; Babio, N; Fito, M; Salas-Salvado, J, Universitat Rovira i Virgili, and Shyam, S; Garcia-Gavilan, JF; Paz-Graniel, I; Gaforio, JJ; Martinez-Gonzalez, MA; Corella, D; Martinez, JA; Alonso-Gomez, AM; Waernberg, J; Vioque, J; Romaguera, D; Lopez-Miranda, J; Estruch, R; Tinahones, FJ; Lapetra, J; Serra-Majem, JL; Bueno-Cavanillas, A; Tur, JA; Sanchez, VM; Pinto, X; Matia-Martin, P; Vidal, J; Vazquez, C; Daimiel, L; Ros, E; Fernandez-Aranda, F; Nishi, SK; Garcia-Regata, O; Toledo, E; Asensio, EM; Castaner, O; Garcia-Rios, A; Torres-Collado, L; Gomez-Gracia, E; Zulet, MA; Ruiz, NG; Casas, R; Cano-Ibanez, N; Tojal-Sierra, L; Gomez-Perez, AM; Sorli, JV; Cinza-Sanjurjo, S; Martin-Pelaez, S; Pena-Orihuela, PJ; Oncina-Canovas, A; Perez-Araluce, R; Zomeno, MD; Chaplin, A; Delgado-Rodriguez, M; Babio, N; Fito, M; Salas-Salvado, J

Abstract

Cross-sectionally, older age and obesity are associated with increased coronavirus disease-2019 (COVID-19) risk. We assessed the longitudinal associations of baseline and changes in adiposity parameters with COVID-19 incidence in older adults at high cardiovascular risk.This analysis included 6874 men and women (aged 55-75 years) with overweight/obesity and metabolic syndrome in the PREDIMED-Plus lifestyle intervention trial for cardiovascular risk reduction. Body weight, body-mass-index (BMI), waist circumference, waist-to-height ratio (WHtR), and a body shape index (ABSI) were measured at baseline and annual follow-up visits. COVID-19 was ascertained by an independent Event Committee until 31 December 2021. Cox regression models were fitted to evaluate the risk of COVID-19 incidence based on baseline adiposity parameters measured 5-6 years before the pandemic and their changes at the visit prior to censoring.At the time of censoring, 653 incident COVID-19 cases occurred. Higher baseline body weight, BMI, waist circumference, and WHtR were associated with increased COVID-19 risk. During the follow-up, every unit increase in body weight (HRadj (95%CI): 1.01 (1.00, 1.03)) and BMI (HRadj: 1.04 (1.003, 1.08)) was associated with increased COVID-19 risk.In older adults with overweight/obesity, clinically significant weight loss may protect against COVID-19.This study is registered at the International Standard Randomized Controlled Trial (ISRCT; http://www.isrctn.com/ISRCTN89898870 ).© 2023. BioMed Central Ltd., part of Springer Nature.

Published
2023

3. Dietary folate intake and metabolic syndrome in participants of PREDIMED-Plus study: a cross-sectional study (Aug, 10.1007/s00394-020-02364-4, 2020)

Author

Navarrete-Munoz E, Vioque J, Toledo E, Oncina-Canovas A, Martinez-Gonzalez M, Salas-Salvado J, Corella D, Fito M, Romaguera D, Alonso-Gomez A, Warnberg J, Martinez J, Serra-Majem L, Estruch R, Tinahones F, Lapetra J, Pinto X, Tur J, Lopez-Miranda J, Bueno-Cavanillas A, Matia-Martin P, Daimiel L, Sanchez V, Vidal J, Blanco A, Ros E, Diez-Espino J, Babio N, Fernandez-Carrion R, Castaner O, Colom A, Compan-Gabucio L, Lete I, Crespo-Oliva E, Abete I, Tomaino L, Casas R, Fernandez-Garcia J, Santos-Lozano J, Sarasa I, Gamez J, Garcia-Rios J, Martin-Pelaez S, Ruiz-Canela M, Diaz-Lopez A, Martinez-Lacruz R, Zomeno M, Rayo E, Selles C, Canudas S, Goday A, and Garcia-de-la-Hera M

Published
2021

5. Transcriptome Signature of Immature and In Vitro-Matured Equine Cumulus-Oocytes Complex.

Author

de la Fuente A, Scoggin C, Bradecamp E, Martin-Pelaez S, van Heule M, Troedsson M, Daels P, Meyers S, and Dini P

Subjects
Animals, Horses, Female, Ovarian Follicle, Gene Expression Profiling, Cumulus Cells, Transcriptome, Oocytes
Abstract

Maturation is a critical step in the development of an oocyte, and it is during this time that the oocyte advances to metaphase II (MII) of the meiotic cycle and acquires developmental competence to be fertilized and become an embryo. However, in vitro maturation (IVM) remains one of the limiting steps in the in vitro production of embryos (IVP), with a variable percentage of oocytes reaching the MII stage and unpredictable levels of developmental competence. Understanding the dynamics of oocyte maturation is essential for the optimization of IVM culture conditions and subsequent IVP outcomes. Thus, the aim of this study was to elucidate the transcriptome dynamics of oocyte maturation by comparing transcriptomic changes during in vitro maturation in both oocytes and their surrounding cumulus cells. Cumulus-oocyte complexes were obtained from antral follicles and divided into two groups: immature and in vitro-matured (MII). RNA was extracted separately from oocytes (OC) and cumulus cells (CC), followed by library preparation and RNA sequencing. A total of 13,918 gene transcripts were identified in OC, with 538 differentially expressed genes (DEG) between immature OC and in vitro-matured OC. In CC, 13,104 genes were expressed with 871 DEG. Gene ontology (GO) analysis showed an association between the DEGs and pathways relating to nuclear maturation in OC and GTPase activity, extracellular matrix organization, and collagen trimers in CC. Additionally, the follicle-stimulating hormone receptor gene ( FSHR ) and luteinizing hormone/choriogonadotropin receptor gene ( LHCGR ) showed differential expressions between CC-MII and immature CC samples. Overall, these results serve as a foundation to further investigate the biological pathways relevant to oocyte maturation in horses and pave the road to improve the IVP outcomes and the overall clinical management of equine assisted reproductive technologies (ART).

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results