16 results on '"Magarotto, M."'
Search Results
2. Numerical suite for cathodeless plasma thrusters
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Magarotto, M., Di Fede, S., Souhair, N., Andrews, S., and Ponti, F.
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- 2022
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3. REGULUS: A propulsion platform to boost small satellite missions
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Manente, M., Trezzolani, F., Magarotto, M., Fantino, E., Selmo, A., Bellomo, N., Toson, E., and Pavarin, D.
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- 2019
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4. Plasma-Based Reflecting and Transmitting Surfaces
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Magarotto, M., primary, Schenato, L., additional, Santagiustina, M., additional, Galtarossa, A., additional, and Capobianco, A.-D., additional
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- 2023
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5. Systemic Catheter-Related Venous Thromboembolism in Children: Data From the Italian Registry of Pediatric Thrombosis
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Lasagni, D., Nosadini, M., Molinari, A. C., Saracco, P., Pelizza, M. F., Piersigilli, F., Putti, M. C., Gaffuri, M., Giordano, P., Lorenzoni, G., Francavilla, A., Trapani, S., Luciani, M., Suppiej, A., Tufano, A., Tormene, D., Martinato, M., Gregori, D., Sartori, S., Simioni, P., Agostini, M., Bassi, B., Bertoni, E., Casani, A., Farinasso, D., Gallo, E., Gentilomo, C., Grassi, M., Lunetta, F., Magarotto, M., Maschio, F., Palmieri, A., Pettenazzo, A., Sangermani, R., Laverda, A., Lasagni, D, Nosadini, M, Molinari, Ac, Saracco, P, Pelizza, Mf, Piersigilli, F, Putti, Mc, Gaffuri, M, Giordano, P, Lorenzoni, G, Francavilla, A, Trapani, S, Luciani, M, Suppiej, A, Tufano, A, Tormene, D, Martinato, M, Gregori, D, Sartori, S, Simioni, P, Systemic Thromboses Working Group of the Italian Registry of Pediatric Thrombosis (RITI Registro Italiano Trombosi, Infantili)., UCL - SSS/IREC/SLUC - Pôle St.-Luc, and UCL - (SLuc) Service de néonatologie
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central venous catheter (CVC) ,pediatric ,children ,Pediatrics, Perinatology and Child Health ,catheter-complications ,heparin ,registry ,thrombosis ,Socio-culturale ,equipment and supplies - Abstract
BackgroundCentral venous catheters (CVCs) represent one of the main risk factors for venous thrombotic events (VTEs) in children.MethodsWe studied the Italian Registry of Pediatric Thrombosis (RITI) with regard to systemic radiologically confirmed CVC-related VTEs (CVC-VTEs) occurred during 6.5 years in children aged 29 days to 18 years.ResultsA total of 78 CVC-VTEs were included, which occurred in 76 patients (40/76, 53% males). CVC-VTEs comprised 67 non-cardiac VTEs (86%) and 11 intracardiac thrombotic events (ICTEs) (14%); the median age at onset was 19 and 17 months, respectively. The most frequent reason for CVC insertion was supportive therapy. The catheters were placed percutaneously in 85% of cases (56/66) and surgically in the remaining 15% (10/66). Peripherally inserted central catheters (PICCs) were used in 47% (31/66) cases, partially implanted catheters in 42% (28/66), non-implantable catheters in 7% (5/66), and totally implanted catheters (Port) in 2% (1/66). CVC-VTEs were symptomatic in 77% of cases (60/78), while in the remaining 23%, they were incidentally detected on the imaging performed for the underlying condition. The median time between CVC insertion and the onset of symptoms was 10 days in non-cardiac VTEs and 39 days in ICTEs. Doppler ultrasound was the diagnostic technique most frequently used. The venous compartment most frequently affected was the veins of the lower extremities (52%, 43/73). Anti-thrombotic treatment was administered in 96% of CVC-VTEs (75/78). About 2.6% (2/76) of patients experienced a second thrombotic event. At discharge, post-thrombotic syndrome was reported in 13.5% (5/37) events with available data, CVC replacement in 10.8% (4/47), and ischemic necrosis with toe finger amputation in 2.7% (1/37). Three patients died due to an underlying condition; no CVC-VTE-related deaths were reported.ConclusionsWe have carried out a registry-based study on CVC-VTEs in the children in Italy, providing the data that may help improve the detection and management of this CVC-related complication.
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- 2022
6. Analysis of the plasma transport in numerical simulations of helicon plasma thrusters
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Souhair, N., primary, Magarotto, M., additional, Ponti, F., additional, and Pavarin, D., additional
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- 2021
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7. 86 Protein C Concentrate for Sepsis-Induced Coagulopathy in Newborn
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Decembrino, L, primary, Stronati, M, additional, Manzato, F, additional, Magarotto, M, additional, De Lazzari, A, additional, Solinas, A, additional, and Compagnoni, G, additional
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- 2005
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8. PROTEIN C CONCENTRATE FOR SEPSIS-INDUCED COAGULOPATHY IN NEWBORN
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DECEMBRINO, L, STRONATI, M, MANZATO, F, MAGAROTTO, M, DE LAZZARI, A, SOLINAS, A, and COMPAGNONI, G
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- 2005
9. Development of a Global Model for the Analysis of Plasma in an Atmosphere-Breathing Cathode-Less Thruster
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Simone Dalle Fabbriche, Nabil Souhair, Mirko Magarotto, Raoul Andriulli, Enrico Corti, Fabrizio Ponti, Dalle Fabbriche S., Souhair N., Magarotto M., Andriulli R., Corti E., and Ponti F.
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global model ,aerospace propulsion ,numerical modeling ,plasma chemistry model ,Aerospace Engineering ,plasma thruster ,atmosphere breathing electric propulsion - Abstract
This study investigates the preliminary propulsive performances of a cathode-less plasma thruster with air as its propellant. The analysis is carried out through a global model and simulates a thruster over a power range of 0 to 50 W. The developed code considers a set of 177 chemical reactions involving 8 different species and includes empirical equations to account for electronegative effects. The analysis presents the steady-state values of species densities at 10 W, 30 W, and 50 W to gain insights into the key characteristics of plasma dynamics. Moreover, the study estimates the thrust and specific impulse and compares the results to data from models that employ xenon and iodine, aiming to understand the performances of air in low-power thrusters. Lastly, the study examines the effects of varying air inflow concentration on the chemistry, analyzing three different orbit altitudes (i.e., 200, 300, and 400 km).
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- 2023
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10. Design and In-orbit Demonstration of REGULUS, an Iodine electric propulsion system
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Lorenzo Cappellini, Alessandro Barbato, Marco Manente, Nabil Souhair, Riccardo Mantellato, Mirko Magarotto, Marco Minute, Alessandro Schiavon, Fabio Trezzolani, Davide Scalzi, Elena Toson, Nicolas Bellomo, A. Selmo, Matteo Duzzi, Francesco Barato, Paola De Carlo, Fabiana Milza, Simone Di Fede, Devis Paulon, Daniele Pavarin, Bellomo N., Magarotto M., Manente M., Trezzolani F., Mantellato R., Cappellini L., Paulon D., Selmo A., Scalzi D., Minute M., Duzzi M., Barbato A., Schiavon A., Di Fede S., Souhair N., De Carlo P., Barato F., Milza F., Toson E., and Pavarin D.
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010302 applied physics ,Propellant ,Physics ,Iodine propellant ,business.industry ,Plume analysis ,Aerospace Engineering ,Thrust ,Propulsion ,01 natural sciences ,010305 fluids & plasmas ,Plume analysi ,Regulus ,Electrically powered spacecraft propulsion ,Space and Planetary Science ,In-orbit Demonstration ,0103 physical sciences ,CubeSat ,Specific impulse ,Electronics ,Aerospace engineering ,CubeSat propulsion ,REGULUS ,business - Abstract
REGULUS is an Iodine-based electric propulsion system. It has been designed and manufactured at the Italian company Technology for Propulsion and Innovation SpA (T4i). REGULUS integrates the Magnetically Enhanced Plasma Thruster (MEPT) and its subsystems, namely electronics, fluidic, and thermo-structural in a volume of 1.5 U. The mass envelope is 2.5 kg, including propellant. REGULUS targets CubeSat platforms larger than 6 U and CubeSat carriers. A thrust T = 0.60 mN and a specific impulse Isp = 600 s are achieved with an input power of P = 50 W; the nominal total impulse is Itot = 3000 Ns. REGULUS has been integrated on-board of the UniSat-7 satellite and its In-orbit Demonstration (IoD) is currently ongoing. The principal topics addressed in this work are: (i) design of REGULUS, (ii) comparison of the propulsive performance obtained operating the MEPT with different propellants, namely Xenon and Iodine, (iii) qualification and acceptance tests, (iv) plume analysis, (v) the IoD.
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- 2022
11. Analysis of the plasma transport in numerical simulations of helicon plasma thrusters
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Fabrizio Ponti, Nabil Souhair, Daniele Pavarin, Mirko Magarotto, Souhair N., Magarotto M., Ponti F., and Pavarin D.
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Physics ,Electron density ,QC1-999 ,General Physics and Astronomy ,Thrust ,Plasma ,Mechanics ,Plasma modeling, Helicon Plasma Thrusters, Electric Propulsion ,Helicon ,Physics::Plasma Physics ,Plasma chemistry ,Energy equation ,Physics::Space Physics ,Diffusion (business) ,Plasma density - Abstract
The accurate simulation of the plasma transport in helicon sources is a key aspect to improve the design of Helicon Plasma Thrusters (HPTs). Specifically, the 3D-VIRTUS code was proven to provide satisfactory estimations of the propulsive performance of realistic HPTs (difference between measures and numerical estimations of the thrust
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- 2021
12. Corrigendum: The new Italian registry of infantile thrombosis (RITI): a reflection on its journey, challenges and pitfalls.
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Pelizza MF, Martinato M, Rosati A, Nosadini M, Saracco P, Giordano P, Luciani M, Ilardi L, Lasagni D, Molinari AC, Bagna R, Palmieri A, Ramenghi LA, Grassi M, Magarotto M, Magnetti F, Francavilla A, Indolfi G, Suppiej A, Gentilomo C, Restelli R, Tufano A, Tormene D, Pin JN, Tona C, Meneghesso D, Rota L, Conti M, Russo G, Lorenzoni G, Gregori D, Sartori S, and Simioni P
- Abstract
[This corrects the article DOI: 10.3389/fped.2023.1094246.]., (© 2024 Pelizza, Martinato, Rosati, Nosadini, Saracco, Giordano, Luciani, Ilardi, Lasagni, Molinari, Bagna, Palmieri, Ramenghi, Grassi, Magarotto, Magnetti, Francavilla, Indolfi, Suppiej, Gentilomo, Restelli, Tufano, Tormene, Pin, Tona, Meneghesso, Rota, Conti, Russo, Lorenzoni, Gregori, Sartori, Simioni and Collaborators of the R.I.T.I. (Italian and Registry of Infantile Thrombosis).)
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- 2024
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13. Products, reactive species and mechanisms of PFOA degradation in a self-pulsing discharge (SPD) plasma reactor.
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Biondo O, Tomei G, Saleem M, Sretenović GB, Magarotto M, Marotta E, and Paradisi C
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- Caprylates chemistry, Carboxylic Acids, Water, Fluorocarbons chemistry, Water Pollutants, Chemical chemistry
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Non-thermal plasma is a promising tool for novel technologies to treat water contaminated by recalcitrant pollutants. We report here on products, reactive species and mechanisms of the efficient degradation of perfluorooctanoic acid (PFOA) achieved with a self-pulsing discharge developed previously in our lab. Air or argon were used as plasma feed gas, ultrapure or tap water as aqueous medium. Identified organic intermediate products arise from chain-shortening and defluorination reactions, the latter achieving not only C-F to C-H exchange (hydro-de-fluorination), as reported in the literature, but also C-F to C-OH exchange (hydroxy-de-fluorination). In contrast with chain-shortening, yielding lower homologues of PFOA via selective cleavage of the C-C bond at the carboxylate group, defluorination occurs at various sites of the alkyl chain giving mixtures of different isomeric products. Plasma generated reactive species were investigated under all experimental conditions tested, using specific chemical probes and optical emission spectroscopy. Cross-analysis of the results revealed a striking direct correlation of energy efficiency for PFOA degradation and for production of plasma electrons. In contrast, no correlation was observed for emission bands of either Ar
+ or OH radical. These results indicate a prevalent role of plasma electrons in initiating PFOA degradation using self-pulsing discharge plasma above the liquid., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.)- Published
- 2023
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14. The new Italian registry of infantile thrombosis (RITI): A reflection on its journey, challenges and pitfalls.
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Pelizza MF, Martinato M, Rosati A, Nosadini M, Saracco P, Giordano P, Luciani M, Ilardi L, Lasagni D, Molinari AC, Bagna R, Palmieri A, Ramenghi LA, Grassi M, Magarotto M, Magnetti F, Francavilla A, Indolfi G, Suppiej A, Gentilomo C, Restelli R, Tufano A, Tormene D, Pin JN, Tona C, Meneghesso D, Rota L, Conti M, Russo G, Lorenzoni G, Gregori D, Sartori S, and Simioni P
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Introduction: Thrombotic events in neonates and children represent a rare although severe occurrence in view of the associated risk of mortality and sequelae. Quality evidence is limited in this field, and registry studies provide an essential base for research. The aim of this paper is to present the new Italian Registry of Infantile Thrombosis (RITI), set it into the scene of international thrombosis and stroke registries, and provide some insight on the challenges associated with registry management., Methods: We present the detailed structure and content of the new RITI registry, a brief overview of its main data, and a reflection on its features, pitfalls and the main challenges related to its management., Results: The RITI, initially started in 2007 and officially re-launched in 2017 after structural modifications, is a non-interventional retrospective and prospective registry study collecting data on neonatal and pediatric patients (0-18 years) who experienced a systemic or cerebral thrombotic event in Italy. The RITI is managed by a multidisciplinary team with expertise in pediatric thrombosis, and participation is open to all Italian physicians, on a voluntary basis. The overall aim of the registry is to acquire new evidence to better characterize the population of children with thrombotic events and improve their management and outcome. 48 Italian pediatric and intensive care units are actively involved in the RITI, including 85 medical doctors from 16 Italian regions. A total of 1,001 neonates and children affected by cerebral or systemic thrombosis have been enrolled., Discussion: The RITI is one of the largest available European registries of neonatal and pediatric thrombosis. National registries like the RITI represent a model for the study of rare conditions based on multidisciplinary and multicenter collaboration, aimed at overcoming the limitations due to small populations of patients, and creating a network of experts for patient referral and continuous education. Moreover, registry studies have a pivotal role in the research on pediatric thrombosis, due to the limited feasibility of high-quality studies. In our experience, the main critical stages, pitfalls and challenges in registry management include adequate registry designing, diffusion, data completeness and quality control., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (© 2023 Pelizza, Martinato, Rosati, Nosadini, Saracco, Giordano, Luciani, Ilardi, Lasagni, Molinari, Bagna, Palmieri, Ramenghi, Grassi, Magarotto, Magnetti, Francavilla, Indolfi, Suppiej, Gentilomo, Restelli, Tufano, Tormene, Pin, Tona, Meneghesso, Rota, Conti, Russo, Lorenzoni, Gregori, Sartori and Simioni.)
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- 2023
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15. Protein C concentrate as adjuvant treatment in neonates with sepsis-induced coagulopathy: a pilot study.
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Decembrino L, D'Angelo A, Manzato F, Solinas A, Tumminelli F, De Silvestri A, De Lazzari S, Padovani E, Magarotto M, Chiandetti L, Saia SO, and Stronati M
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- Antithrombins metabolism, C-Reactive Protein metabolism, Disseminated Intravascular Coagulation metabolism, Female, Humans, Infant, Newborn, Male, Sepsis metabolism, Disseminated Intravascular Coagulation drug therapy, Disseminated Intravascular Coagulation etiology, Protein C therapeutic use, Sepsis complications, Sepsis drug therapy
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The objective of the study is to describe safety and effects of protein C concentrate (PCConc) administration in neonates with sepsis-induced coagulopathy. Eighteen neonates (12 preterm and 6 full term) aged between 1 and 28 days who have severe sepsis (n = 6) or septic shock (n = 12), with coagulopathy and acquired protein C (PC) deficiency received PCConc (i.v. bolus of 100 IU/kg, followed by 50 IU/kg every 6 h for 72 h). Platelet counts, prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen, D-dimer, C-reactive protein (CRP), antithrombin (AT), PC, CRP, and neonatal therapeutic intervention scoring system (NTISS) were assessed before and 24, 48, and 72 h after the study entry. According to Clinical Risk Index for Babies II score (CRIB II score), the expected mortality in preterms was 10%. After 24 h of treatment, PC activity levels increased from an average of 19% to 57%, and they were within normal limits before the last PCConc bolus. During the treatment period, a shortening of PT (P = 0.04) and activated partial thromboplastin time (P = 0.02), and an increase in antithrombin levels (P < 0.0001) were observed, along with a reduction in CRP (P = 0.005) and NTISS values (P = 0.003). No adverse events were observed. This pilot study shows that in neonatal severe sepsis, normalization of PC levels is safe and probably effective in modulating the inflammatory response and in controlling coagulopathy. However, for the potential beneficial effects of PCConc administration on morbidity and mortality, a placebo-controlled, double-blind study is required.
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- 2010
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16. Use of the paediatric bronchoscope, flexible and rigid, in 51 European centres.
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Barbato A, Magarotto M, Crivellaro M, Novello A Jr, Cracco A, de Blic J, Scheinmann P, Warner JO, and Zach M
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- Bronchoalveolar Lavage Fluid, Bronchoscopy adverse effects, Equipment Design, Europe, Fiber Optic Technology, Foreign Bodies pathology, Humans, Immunocompromised Host, Pneumonia pathology, Respiration Disorders pathology, Surveys and Questionnaires, Bronchoscopes, Bronchoscopy statistics & numerical data, Pediatrics instrumentation
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We have undertaken a survey to establish current practices and differences in the use of bronchoscopes in children in European centres. A questionnaire was sent to all 220 members of the Paediatric Assembly of the European Respiratory Society (ERS). The questions concerned the following points: indications for bronchoscopy; site of bronchoscopy; type of sedation; any oxygen supplementation during the procedure; number of procedures performed in the previous 12 months; number of procedures performed in the neonatal intensive care unit; number of bronchoalveolar lavages (BALs); side-effects during and after the procedures; and diagnostic yield. Fifty one European centres (40.8% of the European centres contacted) took part in the study. A total of 7,446 bronchoscopies had been performed in the last 12 months: 4,587 using the flexible bronchoscope and 2,859 using the rigid bronchoscope. At centres using only the fibreoptic bronchoscope, the most frequent indication was "recurrent/persistent pneumonia" (17%); at centres using only the rigid bronchoscope, it was "foreign body inhalation" (36.7%); at centres using both methods, the most frequent indication was "other indications" (23.9%). In 12 months, 2,231 BALs were performed: 1,419 in immunocompetent children and 812 in immunocompromised patients. In centres using only the fibreoptic bronchoscope, the highest yield was for "stridor" (81%); in centres using only the rigid bronchoscope, the highest yield was for "persistent atelectasis" (68%); and in centres using both instruments, it was for "foreign body inhalation" (93%). The results of the study suggest that bronchoscopy in children is now a well-established procedure at several European centres, while others are just beginning to use this technique.
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- 1997
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