1,798 results on '"Lussi, A."'
Search Results
2. Trends over the past 15 years in long-term care in Switzerland: a comparison with Germany, Italy, Norway, and the United Kingdom
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Clara Lussi, Jerome Bickenbach, Rune Halvorsen, and Carla Sabariego
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Long-term care ,Public policy ,Comparative study ,Switzerland ,Nursing services ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background The demographic changes affecting Switzerland and other European countries, including population ageing, will continue to challenge policymakers in building accessible, affordable, comprehensive and high-quality long-term care (LTC) systems. The purpose of this paper is to investigate how Switzerland’s LTC system compares to other European countries, in order to inform how to respond to the increasing need for LTC. We carried out a descriptive study using secondary data from key national and international organizations. Methods By comparing the financing, workforce, service delivery and need for LTC in Switzerland, Germany, Italy, Norway and the United Kingdom, we described similarities and differences in these five European countries between 2005-2019. Thirty-three indicators within five domains were analysed: (1) Population statistics and health expenditure, (2) Need for LTC, (3) LTC financing, (4) LTC service delivery, and (5) LTC workforce. Results Switzerland has the highest life expectancy in comparison to the other four high-income countries. However, similarly to other countries, the years lived with disability are increasing in Switzerland. Switzerland’s public expenditure on LTC as a share of GDP is lower than that of Norway and Germany, yet out-of-pocket expenditure on LTC is highest in Switzerland. Switzerland has the highest proportion of persons receiving formal LTC both in institutions and at home. Switzerland has had the most pronounced increase in the proportion of over 65-year-olds receiving LTC at home. Even though more than fourfold more persons receive care at home, Switzerland still has more workforce in LTC institutions than in home-care. In comparison to Germany and the UK, Switzerland has a lower number of informal carers as a proportion of 50-year-olds and over, as well as fewer nationally available services for informal carers compared to Germany, Italy, Norway and the UK. Conclusions Our comparative study corroborates the importance of improving the affordability of LTC, continuing to support the movement towards home care services, improving the support given to both the professional workforce and informal carers, and improving the amount and quality of LTC data. It also provides a valuable contrast to other European countries to support evidence-informed policymaking.
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- 2024
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- View/download PDF
3. Governing the Automated Welfare State: Translations between AI Ethics and Anti-discrimination Regulation
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Ellinor Blom Lussi, Stefan Larsson, Charlotte Högberg, and Anne Kaun
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Automated Decision-Making ,public-sector governance ,AI ethics ,discrimination ,fairness ,Social pathology. Social and public welfare. Criminology ,HV1-9960 - Abstract
There is an increasing demand to utilize technological possibilities in the Nordic public sector. Automated decision-making (ADM) has been deployed in some areas towards that end. While ADM is associated with a range of benefits, research shows that its use, with elements of AI, also implicates risks of discrimination and unfair treatment, which has stimulated a flurry of normative guidelines. This article seeks to explore how a sample of these international high-level principled ideas on fairness translate into the specific governance of ADM in national public-sector authorities in Sweden. It does so by answering the question of how ideas about AI ethics and fairness are considered in relation to regulation on anti-discrimination in Swedish public-sector governance. By using a Scandinavian institutionalist approach to translation theory, we trace how ideas about AI governance and public-sector governance translate into state-authority practice; specifically, regarding the definition of ADM, how AI has impacted it as both discourse and technology, and the ideas of ‘ethicsʼ and ‘discriminationʼ. The results indicate that there is a variance in how different organizations understand and translate ideas about AI ethics and discrimination. These tensions need to be addressed in order to develop AI governance practices.
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- 2024
- Full Text
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4. Erosive Tooth Wear and Associated Risk Indicators in Schoolchildren from Rural and Urban Areas of the State of Mexico: A Cross-Sectional Study
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José Cuauhtémoc Jiménez-Núñez, Álvaro Edgar González-Aragón Pineda, Teresa Villanueva-Gutiérrez, Rodrigo Leopoldo Longinos-Huerta, Luis Pablo Cruz-Hervert, Adrian Lussi, and Socorro Aída Borges-Yáñez
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erosive tooth wear ,dental erosion ,prevalence ,risk indicators ,rural area ,urban area ,Pediatrics ,RJ1-570 - Abstract
Background and Objective: Limited access to health services and low educational levels are factors in the rural population that are associated with the development of oral pathologies. However, the specific risk indicators contributing to erosive tooth wear (ETW) in these populations remain unclear. The objective of this study was to identify risk indicators associated with the prevalence of erosive tooth wear (ETW) in schoolchildren aged 8–12 years from rural and urban areas in the State of Mexico. Methods: A cross-sectional study was carried out in public schools in rural and urban areas. The prevalence of ETW was evaluated using the Basic Erosive Wear Examination (BEWE). The risk indicators studied were gastroesophageal reflux, vomiting, vitamin C, food, beverages, dental hygiene, bruxism, and hyposalivation. Logistic regression models were used to calculate odds ratios (OR) and 95% confidence intervals (CI). Results: The prevalence of ETW was higher in the rural area (77.3%) compared to the urban area (51.2%) (p = 0.001). The odds of presenting ETW were more than twice in schoolchildren from rural areas compared to those from urban areas (OR: 2.25, 95% CI: 1.11–3.98). Risk indicators varied between rural and urban populations, with different factors such as the consumption of fresh tomato sauce, orange, tangerine, atole (artisanal corn-based drink), and teeth grinding in the rural area, and lemon, soft drink, fruit juice consumption, and the simplified oral hygiene index in the urban area (p < 0.05). Conclusions: To prevent ETW, strategies offering tailored dietary and hygiene advice should be proposed, considering the specific conditions of each geographic area.
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- 2024
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5. Plant extracts have dual mechanism on the protection against dentine erosion: action on the dentine substrate and modification of the salivary pellicle
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Niemeyer, Samira Helena, Baumann, Tommy, Lussi, Adrian, Scaramucci, Tais, and Carvalho, Thiago Saads
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- 2023
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6. Autonomous Magnetic Navigation in Endoscopic Image Mosaics
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Michelle Mattille, Quentin Boehler, Jonas Lussi, Nicole Ochsenbein, Ueli Moehrlen, and Bradley J. Nelson
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autonomous navigation ,fetal surgery ,magnetic navigation ,medical robotics ,mosaicking ,Science - Abstract
Abstract Endoscopes navigate within the human body to observe anatomical structures with minimal invasiveness. A major shortcoming of their use is their narrow field‐of‐view during navigation in large, hollow anatomical regions. Mosaics of endoscopic images can provide surgeons with a map of the tool's environment. This would facilitate procedures, improve their efficiency, and potentially generate better patient outcomes. The emergence of magnetically steered endoscopes opens the way to safer procedures and creates an opportunity to provide robotic assistance both in the generation of the mosaic map and in navigation within this map. This paper proposes methods to autonomously navigate magnetic endoscopes to 1) generate endoscopic image mosaics and 2) use these mosaics as user interfaces to navigate throughout the explored area. These are the first strategies, which allow autonomous magnetic navigation in large, hollow organs during minimally invasive surgeries. The feasibility of these methods is demonstrated experimentally both in vitro and ex vivo in the context of the treatment of twin‐to‐twin transfusion syndrome. This minimally invasive procedure is performed in utero and necessitates coagulating shared vessels of twin fetuses on the placenta. A mosaic of the vasculature in combination with autonomous navigation has the potential to significantly facilitate this challenging surgery.
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- 2024
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7. Juventudes, uberização e informalidade
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Marina Batista Chaves Azevedo de Souza and Isabela Aparecida de Oliveira Lussi
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Juventude ,Trabalho ,Trabalho Informal ,Uberização do Trabalho ,Trabalho e Educação ,Labor. Work. Working class ,HD4801-8943 ,Social sciences (General) ,H1-99 - Abstract
Documentos oficiais e pesquisas científicas explicitam que a juventude brasileira pobre se insere em trabalhos informais e uberizados por necessidade, e não por desejo. Este estudo etnográfico proporcionou encontros em profundidade com jovens entregadores de comida na Paraíba/Brasil, durante os anos de 2019 e 2020, utilizando cadernos de campo, questionário socioeconômico e dados audiovisuais. Realizou-se análises de dados descritivas e teóricas, com enquadramento teórico de base materialista histórica. Identificou-se problemáticas sociais e de trabalho, assim como repercussões negativas do trabalho informal/uberizado na educação de jovens. Aponta-se que os serviços responsáveis (ligados aos jovens, à educação e ao trabalho) devem elaborar estratégias intersetoriais de inserção/permanência de jovens na educação e no mercado de trabalho, sempre compreendendo as especificidades das juventudes, a importância da educação e da inserção em trabalhos dignos, seguros e próximos dos desejos dos envolvidos.
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- 2023
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8. Plant extracts have dual mechanism on the protection against dentine erosion: action on the dentine substrate and modification of the salivary pellicle
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Samira Helena Niemeyer, Tommy Baumann, Adrian Lussi, Tais Scaramucci, and Thiago Saads Carvalho
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Medicine ,Science - Abstract
Abstract To investigate the effect of some polyphenol-rich plant extracts on the protection of dentine against demineralization, both acting on the dentine and on the salivary pellicle. Dentine specimens (n = 180) were randomly distributed into 6 experimental groups (n = 30/group): Control (deionized water), Açaí extract, Blueberry extract, Green tea extract, Grape seed extract, and Sn2+/F− (mouthrinse containing stannous and fluoride). Each group was further divided into two subgroups (n = 15), according to the site of action of the substance: on the dentine surface (D) or on the salivary pellicle (P). The specimens were submitted to 10 cycles: 30 min incubation in human saliva (P) or only in humid chamber (D), 2 min immersion in experimental substances, 60 min of incubation in saliva (P) or not (D), and 1 min erosive challenge. Dentine surface loss (DSL), amount of degraded collagen (dColl) and total calcium release were analyzed. Green tea, Grape seed and Sn2+/F− showed significant protection, with least DSL and dColl. The Sn2+/F− showed better protection on D than on P, whereas Green tea and Grape seed showed a dual mode of action, with good results on D, and even better on P. Sn2+/F− showed the lowest values of calcium release, not differing only from Grape seed. Sn2+/F− is more effective when acting directly on the dentine surface, while Green tea and Grape seed have a dual mode of action: with a positive effect on the dentine surface itself, but an improved efficacy in the presence of the salivary pellicle. We further elucidate the mechanism of action of different active ingredients on dentine erosion, where Sn2+/F− acts better on the dentine surface, but plant extracts have a dual mode of action, acting on the dentine itself as well as on the salivary pellicle, improving the protection against acid demineralization.
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- 2023
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9. Association of salivary parameters and erosive tooth wear in preschool children
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Mayra Manoella PEREZ, Ana Clara Magalhães LUS, Priscila Hernandez CAMPOS, Stella Ferreira do AMARAL, Adrian LUSSI, Michele Baffi DINIZ, and Renata Oliveira GUARÉ
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Saliva ,Child ,Tooth Erosion ,Tooth, Deciduous ,Dentistry ,RK1-715 - Abstract
Abstract The aims of this study were to 1) assess the association between erosive tooth wear (ETW) according to the BEWE (Basic Erosive Wear Examination) scoring system and salivary parameters and 2) compare salivary parameters according to ETW severity in the subgroup of children with ETW. This cross-sectional study included 52 preschool children aged 5 years paired by sex. A calibrated examiner assessed ETW using BEWE criteria, and stimulated saliva was collected to determine salivary flow, osmolality, pH, and buffering capacity. The children were divided into two groups: without ETW (n=26; BEWE score 0) and with ETW (n=26; BEWE scores 1 and 2). Logistic regression analysis was used to determine the magnitude of the association between ETW and salivary parameters and estimates of odds ratios (OR). In the unadjusted analysis, the ETW group was more likely to have lower salivary flow (OR = 0.079; 95%CI = 0.013–0.469; p = 0.005) and lower osmolality (OR = 0.993; 95%CI = 0.985–1.000; p = 0.049). In the adjusted analysis, salivary flow remained significantly associated with ETW (OR = 0.087; 95%CI = 0.014–0.533; p = 0.008). Lower salivary osmolality values were observed in ETW, especially in preschool children with more severe ETW (BEWE score 2). Receiver operating characteristic (ROC) determined a salivary osmolality cutoff point of < 201 for the presence of ETW. In conclusion, salivary flow rate was significantly associated with ETW prevalence. Lower values of salivary osmolality were observed in preschool children with distinct erosive lesions with significant loss of tooth structure (BEWE 2).
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- 2023
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10. Acquired enamel pellicle protects gastroesophageal reflux disease patients against erosive tooth wear
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Tatiana MARTINI, Daniela RIOS, Aline DIONIZIO, Luiza de Paula Silva CASSIANO, Cíntia Maria de Souza e SILVA, Even Akemi TAIRA, Talita Mendes Oliveira VENTURA, João Victor Frazão CÂMARA, Tamara Teodoro Araujo, Ana Carolina MAGALHÃES, Thiago Saads CARVALHO, Tommy BAUMANN, Adrian LUSSI, Ricardo Brandt de OLIVEIRA, Regina Guenka PALMA-DIBB, and Marília Afonso Rabelo BUZALAF
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Tooth Erosion ,Dental Pellicle ,Proteomics ,Dentistry ,RK1-715 - Abstract
Abstract The objective of this study was to compare the protein profile of the acquired enamel pellicle (AEP) formed in vivo in patients with or without gastroesophageal reflux disease (GERD), and with or without erosive tooth wear (ETW). Twenty-four volunteers were divided into 3 groups: 1) GERD and ETW; 2) GERD without ETW; and 3) control (without GERD). The AEP formed 120 min after prophylaxis was collected from the lingual/palatal surfaces. The samples were subjected to mass spectrometry (nLC-ESI-MS/MS) and label-free quantification by Protein Lynx Global Service software. A total of 213 proteins were identified, or 119, 92 and 106 from each group, respectively. Group 2 showed a high number of phosphorylated and calcium-binding proteins. Twenty-three proteins were found in all the groups, including 14-3-3 protein zeta/delta and 1-phosphatidylinositol. Several intracellular proteins that join saliva after the exfoliation of oral mucosa cells might have the potential to bind hydroxyapatite, or participate in forming supramolecular aggregates that bind to precursor proteins in the AEP. Proteins might play a central role in protecting the dental surface against acid dissolution.
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- 2023
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11. Linguistics Pattern on Acehnese Reduplicative System: Classifications and Meanings
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Ika Apriani Fata, Bukhari Daud, Lussi Maunira, and Eka Wahjuningsih
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linguistics pattern ,meaning ,reduplication ,acehnese language ,Language and Literature - Abstract
The significance of reduplication in language studies was to construct a linguistics pattern. However, linguists tend to disregard the functions of individual creativity and the core language meaning-making approach at the discourse level. Therefore, we should investigate this intriguing topic more to describe the repetition of words. Many studies analyzed classification reduplication in Acehnese through documentation techniques, in contrast, this current study investigated classifications and meanings of reduplication in Acehnese through observation and interview. Sulaiman's paradigm as the framework stated that reduplication had three parts: complete, affix, and ablaut reduplication. In addition, the researchers used the Ali et al. framework, which suggested eight meanings of reduplication, mainly grammatical meanings. The findings revealed that full reduplication was the most common among the 100 data of utterances. Furthermore, the meanings of reduplications are to convey the collective and distributive meaning, to express resemblance, and to express simultaneously and continuously were not discovered. The current study looked at how people could use morphological perspectives on reduplication in community discussions. Acehnese reduplication may vanish.
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- 2022
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12. Rinsing solutions containing natural extracts and fluoride prevent enamel erosion in vitro
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Tommy BAUMANN, Samira Helena NIEMEYER, Adrian LUSSI, Taís SCARAMUCCI, and Thiago Saads CARVALHO
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Dental pellicle ,Dental erosion ,Enamel ,Polyphenols ,Mouth rinse ,Dentistry ,RK1-715 - Abstract
Abstract Polyphenols interact with salivary proteins and thus can improve the pellicle’s erosion protective properties. This effect could be exploited to create rinsing solutions with polyphenols as active ingredients for erosion prevention. Different from the current gold standard for erosion protective rinsing solutions, these rinses would not rely on stannous ions. This would offer alternatives for patients with concerns regarding the composition of rinsing solutions and preferring bio-products. Objective To develop an erosion-preventive rinsing solution containing natural polyphenol-rich extracts. Methodology Solutions were prepared with polyphenols from either grapeseed extract or cranberry extract, 500 ppm fluoride added, and additionally flavors and sweeteners. Controls were deionized water, 500 ppm fluoride solution, and the gold standard rinse in the field (Sn2+/F-). In total, 135 enamel specimens (n=15/group) were subjected to five cycles of salivary pellicle formation (30 min, 37°C), modification with the solutions (2 min, 25°C), further salivary pellicle formation (60 min, 37°C), and erosive challenge (1 min, 1% citric acid, pH 3.6). Relative surface microhardness (rSMH), surface reflection intensity (rSRI), and amount of calcium release (CaR) were investigated. Data were analyzed with Kruskal-Wallis and Wilcoxon rank sum tests (α=0.05). Results The polyphenol solutions containing fluoride, as well as additional flavors, protected enamel better than fluoride alone, and similar to the Sn2+/F- solution, when investigating both rSMH and CaR. When measuring rSRI, Sn2+/F- showed the best protection, while the polyphenol solutions were similar to fluoride. Conclusion For two of the three assessed parameters (rSMH and CaR), both developed polyphenol-rich rinsing solutions were able to protect enamel from erosion, improving/potentializing the effect of fluoride and matching the protection offered by the current gold standard rinsing solution.
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- 2023
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13. Conhecimento produzido sobre saúde mental e economia solidária: uma revisão de escopo/Conocimiento producido sobre salud mental y economía solidaria: una revisión documental/Knowledge produced about mental health and solidarity economy: a scope review
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Mazaro, Lisabelle Manente, Camargo, Mariane de Góes, and Lussi, Isabela Aparecida de Oliveira
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- 2022
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14. Differences in susceptibility of deciduous and permanent teeth to erosion exist, albeit depending on protocol design and method of assessment
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Carvalho, Thiago Saads, Lussi, Adrian, Schlueter, Nadine, and Baumann, Tommy
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- 2022
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15. Differences in susceptibility of deciduous and permanent teeth to erosion exist, albeit depending on protocol design and method of assessment
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Thiago Saads Carvalho, Adrian Lussi, Nadine Schlueter, and Tommy Baumann
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Medicine ,Science - Abstract
Abstract Controversial results showing that deciduous teeth are more susceptible to erosion than permanent teeth might be related to study designs. We investigated how different conditions (pH: 3.0, 4.0, 5.0; acid agitation: gentle or vigorous; acid exposure times: 1–5 min) affect the susceptibility of both teeth to erosion. Enamel specimens (90 deciduous, 90 permanent) were distributed into groups (n = 15 permanent, n = 15 deciduous) according to acid pH (pH 5, 4 or 3) and agitation (gentle or vigorous) during erosive challenge. Both milder (less incubation time, gentle agitation, and higher pH) and more severe (longer incubation times, vigorous shaking, and lower pH) conditions were used. Demineralization was measured by relative surface microhardness (rSMH) and calcium released to the acid. Demineralization increased gradually for both teeth with increasing incubation time, agitation (gentle or vigorous), and with decreasing acid pH. The differences between deciduous and permanent teeth depended on the protocol design and assessment method. Under milder conditions, demineralization was better detectable with rSMH. Under more severe conditions, differences were more perceptible with calcium analyses. Differences exist in the susceptibility to erosion between deciduous and permanent teeth, but they are only distinguishable when the appropriate assessment method is used for the specific erosive condition.
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- 2022
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16. Erosive Tooth Wear and Associated Risk Indicators in Schoolchildren from Rural and Urban Areas of the State of Mexico: A Cross-Sectional Study.
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Jiménez-Núñez, José Cuauhtémoc, González-Aragón Pineda, Álvaro Edgar, Villanueva-Gutiérrez, Teresa, Longinos-Huerta, Rodrigo Leopoldo, Cruz-Hervert, Luis Pablo, Lussi, Adrian, and Borges-Yáñez, Socorro Aída
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TOOTH erosion -- Risk factors ,TOOTH erosion ,CLINICAL medicine ,CROSS-sectional method ,RESEARCH funding ,CRONBACH'S alpha ,RECEIVER operating characteristic curves ,KEY performance indicators (Management) ,LOGISTIC regression analysis ,STATISTICAL sampling ,QUESTIONNAIRES ,AGE distribution ,DESCRIPTIVE statistics ,CHI-squared test ,MANN Whitney U Test ,MULTIVARIATE analysis ,STUDENTS ,ODDS ratio ,RURAL population ,INTRACLASS correlation ,MEDICAL records ,ACQUISITION of data ,STATISTICS ,FOOD habits ,CONFIDENCE intervals ,DATA analysis software ,SCHOOL health services ,CHILDREN - Abstract
Background and Objective: Limited access to health services and low educational levels are factors in the rural population that are associated with the development of oral pathologies. However, the specific risk indicators contributing to erosive tooth wear (ETW) in these populations remain unclear. The objective of this study was to identify risk indicators associated with the prevalence of erosive tooth wear (ETW) in schoolchildren aged 8–12 years from rural and urban areas in the State of Mexico. Methods: A cross-sectional study was carried out in public schools in rural and urban areas. The prevalence of ETW was evaluated using the Basic Erosive Wear Examination (BEWE). The risk indicators studied were gastroesophageal reflux, vomiting, vitamin C, food, beverages, dental hygiene, bruxism, and hyposalivation. Logistic regression models were used to calculate odds ratios (OR) and 95% confidence intervals (CI). Results: The prevalence of ETW was higher in the rural area (77.3%) compared to the urban area (51.2%) (p = 0.001). The odds of presenting ETW were more than twice in schoolchildren from rural areas compared to those from urban areas (OR: 2.25, 95% CI: 1.11–3.98). Risk indicators varied between rural and urban populations, with different factors such as the consumption of fresh tomato sauce, orange, tangerine, atole (artisanal corn-based drink), and teeth grinding in the rural area, and lemon, soft drink, fruit juice consumption, and the simplified oral hygiene index in the urban area (p < 0.05). Conclusions: To prevent ETW, strategies offering tailored dietary and hygiene advice should be proposed, considering the specific conditions of each geographic area. [ABSTRACT FROM AUTHOR]
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- 2024
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17. Risk analysis Erosive Tooth Wear (ETW): checklist for a quick assessment of the risk factors for ETW in the dental practice
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Niemeyer, Samira H, primary, Jaeggi, Thomas, additional, Ramseyer, Simon, additional, Tennert, Christian, additional, Imfeld, Carola, additional, Lussi, Adrian, additional, and Abou-Ayash, Bedram, additional
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- 2024
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18. Autonomous Magnetic Navigation in Endoscopic Image Mosaics
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Mattille, Michelle, primary, Boehler, Quentin, additional, Lussi, Jonas, additional, Ochsenbein, Nicole, additional, Moehrlen, Ueli, additional, and Nelson, Bradley J., additional
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- 2024
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19. Magnetically Guided Laser Surgery for the Treatment of Twin‐to‐Twin Transfusion Syndrome
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Jonas Lussi, Simone Gervasoni, Michelle Mattille, Roland Dreyfus, Quentin Boehler, Michael Reinehr, Nicole Ochsenbein, Bradley J Nelson, and Ueli Moehrlen
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fetal surgery ,laser surgery ,magnetic navigation systems ,medical robotics ,twin-to-twin transfusion syndrome ,Computer engineering. Computer hardware ,TK7885-7895 ,Control engineering systems. Automatic machinery (General) ,TJ212-225 - Abstract
Twin‐to‐twin transfusion syndrome (TTTS) is a severe disorder that often leads to the death of monochorionic twin fetuses, if left untreated. Current prenatal interventions to treat the condition involve the use of rigid fetoscopes for targeted laser coagulation of the vascular anastomoses. These tools are limited in their area of operation, making treatment challenging, especially in cases with anterior placentation. Herein, a robotic platform to perform this task using remote magnetic navigation is proposed. In contrast to rigid tools, the presented custom magnetic fetoscope is highly flexible, dexterous, and has considerable advantages, including safety and precision. A visual servoing algorithm that allows the surgeon to navigate in the uterus with submillimeter precision is introduced. The system has been validated on ex vivo human placentas in a setting that mimics the real intraoperative conditions.
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- 2022
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20. Relationship between intrinsic and extrinsic factors with Erosive Tooth Wear in adults: a cross-sectional study
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Valeria RAMIREZ, Adrian LUSSI, María Loreto MARRÓ FREITTE, Pamela VASQUEZ, and Vicente ARÁNGUIZ
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Tooth Wear ,Tooth Erosion ,Risk Factors ,Oral Health ,Dentistry ,RK1-715 - Abstract
Abstract The objective of this study was to explore the relationship between intrinsic and extrinsic factors and a high cumulative score of the Basic Erosive Wear Examination (BEWE) in a Chilean adult group. A cross-sectional study was performed with the Ethics Committee’s approval from the Universidad de los Andes. A consecutive adult (18 to 46 years old) sampling (n = 553) from the Health Center in San Bernardo-Chile, was selected from September 2016 to January 2017. Dental exams were performed by two trained and calibrated examiners, according to the BEWE index. In order to search for potentially related factors, a hetero-applied questionnaire previously developed and evaluated was applied. Our interest was individuals with severe erosion tooth wear (BEWE ≥ 14). Logistic regression models reporting crude odds ratio (OR) and adjusted OR by age, 95% confidence interval (95%CI), and p-values were estimated. Variables, odds ratios and 95% CI related with BEWE ≥ 14 were: age (OR 1.1 [1.07–1.14]); currently drinking alcohol (OR 1.59 [1.06-2.39]); esophagitis (OR 8.22 [1.60–42.22]); difficulty to swallow (OR 2.45 [1.10–5.44]); chest pain (OR 2.07 [1.18–3.64]); anorexia (OR 3.82 [1.07–13.68]); vitamin C intake (OR 1.92 [1.08–3.43]). Age, alcohol consumption, self-reported esophagitis, history of gastric symptoms, anorexia, and vitamin C intake were related as risk factors to high BEWE scores in this sample of Chilean adults in San Bernardo, Chile.
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- 2022
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21. Práticas emancipatórias em Saúde Mental
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Isabela Aparecida de Oliveira Lussi, Adriana Leão, and Tatiana Dimov
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Saúde Mental ,Emancipação social ,Reforma psiquiátrica ,Rede de atenção psicossocial ,Public aspects of medicine ,RA1-1270 - Abstract
Este artigo visa refletir sobre a potência de ações e serviços no campo da Saúde Mental no sistema de saúde pública brasileira, com o intuito de fomentar práticas emancipatórias, sobretudo no contexto de retrocessos vivenciados com a atual Nova Política Nacional de Saúde Mental, que se contrapõe aos preceitos da Reforma Psiquiátrica. Ancoradas em elementos teóricos acerca da emancipação, da sociologia das ausências e da sociologia das emergências, discutimos os grupos de ajuda e suporte mútuos, os grupos de ouvidores de vozes, os centros de convivência e as iniciativas de Economia Solidária, os quais visam à superação da lógica da monocultura do saber, valorizando o conhecimento dos usuários e adotando práticas horizontalizadas e autogestionárias. Tais experiências precisam ser sistematizadas, vivenciadas e multiplicadas para que seja possível o desenvolvimento de redes de cuidado com potencial emancipatório.
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- 2022
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22. Governing the Automated Welfare State : Translations between AI Ethics and Anti-discrimination Regulation
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Lussi, Ellinor Blom, Larsson, Stefan, Högberg, Charlotte, Kaun, Anne, Lussi, Ellinor Blom, Larsson, Stefan, Högberg, Charlotte, and Kaun, Anne
- Abstract
There is an increasing demand to utilize technological possibilities in the Nordic public sector. Automated decision-making (ADM) has been deployed in some areas towards that end. While ADM is associated with a range of benefits, research shows that its use, with elements of AI, also implicates risks of discrimination and unfair treatment, which has stimulated a flurry of normative guidelines. This article seeks to explore how a sample of these international high-level principled ideas on fairness translate into the specific governance of ADM in national public-sector authorities in Sweden. It does so by answering the question of how ideas about AI ethics and fairness are considered in relation to regulation on anti-discrimination in Swedish public-sector governance. By using a Scandinavian institutionalist approach to translation theory, we trace how ideas about AI governance and public-sector governance translate into state-authority practice; specifically, regarding the definition of ADM, how AI has impacted it as both discourse and technology, and the ideas of ‘ethicsʼ and ‘discriminationʼ. The results indicate that there is a variance in how different organizations understand and translate ideas about AI ethics and discrimination. These tensions need to be addressed in order to develop AI governance practices.
- Published
- 2024
- Full Text
- View/download PDF
23. Clinical validation of near-infrared light transillumination for early proximal caries detection using a composite reference standard
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Stratigaki, Eirini, Jost, Fabian N., Kühnisch, Jan, Litzenburger, Friederike, Lussi, Adrian, and Neuhaus, Klaus W.
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- 2020
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24. Enamel pearls
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Schaffner, Markus, primary, Stich, Herrmann, additional, and Lussi, Adrian, additional
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- 2024
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25. Denticles: dental pulp calculi
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Schaffner, Markus, primary, Stich, Herrmann, additional, and Lussi, Adrian, additional
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- 2024
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26. Riflessioni su percorsi spirituali ed ecclesiali di brasiliani immigrati in Italia
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Carmem Lussi
- Subjects
Colonies and colonization. Emigration and immigration. International migration ,JV1-9480 - Published
- 2020
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27. Inverser la classe : quelles expériences ? Analyse de l’activité des élèves
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Valérie Lussi Borer, Alain Muller, and Stéphanie Rubi
- Subjects
pedagogy: methods and tools ,change and innovation ,educational research ,autonomy and socialization ,ICT and digital ,professionalization ,Education - Abstract
This contribution is part of a multidisciplinary collective research project on the transformation of the activity of teachers and students in the context of the "flipped classroom". Based on semi-directive interviews and self-confrontations conducted with teachers and their students, data from student interviews were analyzed using the learning registers proposed by Elisabeth Bautier and Patrick Rayou crossed with Charles Sanders Peirce’s semiotics. The first results show differences between the registers that the students mobilize according to the nature of the interview, as well as in the articulation of the registers. The combination of semi-directive interviews and self-confrontations opens up promising methodological perspectives, allowing both students to express their activity in a richer way and researchers to better apprehend the experience lived by the students.
- Published
- 2022
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28. Thermoset Shape Memory Polymer Variable Stiffness 4D Robotic Catheters
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Michael Mattmann, Carmela De Marco, Francesco Briatico, Stefano Tagliabue, Aron Colusso, Xiang‐Zhong Chen, Jonas Lussi, Christophe Chautems, Salvador Pané, and Bradley Nelson
- Subjects
catheters ,composite materials ,shape memory polymers ,thermoset polymers ,variable stiffness ,Science - Abstract
Abstract Variable stiffness catheters are typically composed of an encapsulated core. The core is usually composed of a low melting point alloy (LMPA) or a thermoplastic polymer (TP). In both cases, there is a need to encapsulate the core with an elastic material. This imposes a limit to the volume of variable stiffness (VS) material and limits miniaturization. This paper proposes a new approach that relies on the use of thermosetting materials. The variable stiffness catheter (VSC) proposed in this work eliminates the necessity for an encapsulation layer and is made of a unique biocompatible thermoset polymer with an embedded heating system. This significantly reduces the final diameter, improves manufacturability, and increases safety in the event of complications. The device can be scaled to sub‐millimeter dimensions, while maintaining a high stiffness change. In addition, integration into a magnetic actuation system allows for precise actuation of one or multiple tools.
- Published
- 2022
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29. In Vitro Study on Green Propolis as a Potential Ingredient of Oral Health Care Products
- Author
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Achille Coluccia, Fabienne Matti, Xilei Zhu, Adrian Lussi, Alexandra Stähli, Anton Sculean, and Sigrun Eick
- Subjects
Brazilian green propolis ,monocytic cells ,biofilm ,toothpaste ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Propolis is increasingly being discussed as an alternative to commonly used antiseptics. This in vitro study focused on the ethanolic extract of green Brazilian propolis (EEPg) as an additive in an oral health care product. We investigated (i) a potential inflammation-modulation activity of EEPg when a periodontal or Candida biofilm was exposed to monocytic (MONO-MAC-6) cells, (ii) the adhesion of oral pathogens to gingival keratinocytes and (iii) the antimicrobial and antibiofilm effect of different toothpaste formulations. EEPg decreased the levels of interleukin (IL)-1β and increased IL-10 in MONO-MAC cells challenged with a periodontal biofilm. In contact with TIGK cells, EEPg reduced the numbers of adherent Porphyromonas gingivalis to 0.5% but did not affect the adhesion of Candida albicans. The frequent brushing of a cariogenic biofilm with a toothpaste supplemented with EEPg reduced the surface microhardness loss of enamel specimens. Mixing an experimental erythritol toothpaste with 25 and 50 mg/mL of EEPg confirmed the antibacterial activity of EEPg against oral bacteria and particularly inhibited periodontal biofilm formation. The suggested toothpaste formulations seem to have potential in the prevention of caries, gingivitis and periodontitis and should be evaluated in further in vitro research and in clinical trials.
- Published
- 2022
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30. ArDM: first results from underground commissioning
- Author
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Badertscher, A., Bay, F., Bourgeois, N., Cantini, C., Curioni, A., Daniel, M., Degunda, U., Di Luise, S., Epprecht, L., Gendotti, A., Horikawa, S., Knecht, L., Lussi, D., Maire, G., Montes, B., Murphy, S., Natterer, G., Nikolics, K., Nguyen, K., Periale, L., Ravat, S., Resnati, F., Romero, L., Rubbia, A., Santorelli, R., Sergiampietri, F., Sgalaberna, D., Viant, T., and Wu, S.
- Subjects
Physics - Instrumentation and Detectors - Abstract
The Argon Dark Matter experiment is a ton-scale double phase argon Time Projection Chamber designed for direct Dark Matter searches. It combines the detection of scintillation light together with the ionisation charge in order to discriminate the background (electron recoils) from the WIMP signals (nuclear recoils). After a successful operation on surface at CERN, the detector was recently installed in the underground Laboratorio Subterr\'aneo de Canfranc, and the commissioning phase is ongoing. We describe the status of the installation and present first results from data collected underground with the detector filled with gas argon at room temperature., Comment: 6 pages, 3 figures, Light Detection In Noble Elements (LIDINE 2013)
- Published
- 2013
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31. Status of the ArDM Experiment: First results from gaseous argon operation in deep underground environment
- Author
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ArDM Collaboration, Badertscher, A., Bay, F., Bourgeois, N., Cantini, C., Daniel, M., Degunda, U., DiLuise, S., Epprecht, L., Gendotti, A., Horikawa, S., Knecht, L., Lussi, D., Maire, G., Montes, B., Murphy, S., Natterer, G., Nikolics, K., Nguyen, K., Periale, L., Ravat, S., Resnati, F., Romero, L., Rubbia, A., Santorelli, R., Sergiampietri, F., Sgalaberna, D., Viant, T., and Wu, S.
- Subjects
Physics - Instrumentation and Detectors - Abstract
The Argon Dark Matter (ArDM-1t) experiment is a ton-scale liquid argon (LAr) double-phase time projection chamber designed for direct Dark Matter searches. Such a device allows to explore the low energy frontier in LAr. After successful operation on surface at CERN, the detector has been deployed underground and is presently commissioned at the Canfranc Underground Laboratory (LSC). In this paper, we describe the status of the installation and present first results on data collected in gas phase., Comment: 21 pages, 20 figures
- Published
- 2013
32. First operation and performance of a 200 lt double phase LAr LEM-TPC with a 40x76 cm^2 readout
- Author
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Badertscher, A., Curioni, A., Degunda, U., Epprecht, L., Gendotti, A., Horikawa, S., Knecht, L., Natterer, D. Lussi G., Nguyen, K., Resnati, F., Rubbia, A., and Viant, T.
- Subjects
Physics - Instrumentation and Detectors ,High Energy Physics - Experiment - Abstract
In this paper we describe the design, construction, and operation of a first large area double-phase liquid argon Large Electron Multiplier Time Projection Chamber (LAr LEM-TPC). The detector has a maximum drift length of 60 cm and the readout consists of a $40\times 76$ cm$^2$ LEM and 2D projective anode to multiply and collect drifting charges. Scintillation light is detected by means of cryogenic PMTs positioned below the cathode. To record both charge and light signals, we have developed a compact acquisition system, which is scalable up to ton-scale detectors with thousands of charge readout channels. The acquisition system, as well as the design and the performance of custom-made charge sensitive preamplifiers, are described. The complete experimental setup has been operated for a first time during a period of four weeks at CERN in the cryostat of the ArDM experiment, which was equipped with liquid and gas argon purification systems. The detector, exposed to cosmic rays, recorded events with a single-channel signal-to-noise ratio in excess of 30 for minimum ionising particles. Cosmic muon tracks and their $\delta$-rays were used to assess the performance of the detector, and to estimate the liquid argon purity and the gain at different amplification fields., Comment: 23 pages, 21 figures
- Published
- 2013
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33. Uma Formação Profissional Universitária para todos os Professores: o exemplo da Suíça no século XX
- Author
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Rita Hofstetter, Bernard Schneuwly, and Valérie Lussi Borer
- Subjects
professor primário. professor secundário. formação profissional universitária. saber de referência. ciências da educação. ,Education ,Education (General) ,L7-991 - Abstract
Este artigo reconstitui e compara a história da formação profissional universitária de professores do ensino primário e secundário durante o século XX na Suíça, cotejando os desenvolvimentos nas áreas culturais germanófonas e francófonas. Ele apresenta e discute três tensões inerentes ao processo de universitarização: 1) entre as diferentes instâncias envolvidas na definição dos cursos de formação; 2) em torno da natureza dos saberes de referência que sustentam a profissão docente; 3) em relação à divisão interna da profissão entre os níveis de ensino primário e secundário.
- Published
- 2021
34. A Submillimeter Continuous Variable Stiffness Catheter for Compliance Control
- Author
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Jonas Lussi, Michael Mattmann, Semih Sevim, Fabian Grigis, Carmela De Marco, Christophe Chautems, Salvador Pané, Josep Puigmartí‐Luis, Quentin Boehler, and Bradley J. Nelson
- Subjects
magnetic actuation ,medical robotics ,soft robotics ,variable stiffness ,Science - Abstract
Abstract Minimally invasive robotic surgery often requires functional tools that can change their compliance to adapt to the environment and surgical needs. This paper proposes a submillimeter continuous variable stiffness catheter equipped with a phase‐change alloy that has a high stiffness variation in its different states, allowing for rapid compliance control. Variable stiffness is achieved through a variable phase boundary in the alloy due to a controlled radial temperature gradient. This catheter can be safely navigated in its soft state and rigidified to the required stiffness during operation to apply a desired force at the tip. The maximal contact force that the catheter applies to tissue can be continuously modified by a factor of 400 (≈20 mN–8 N). The catheter is equipped with a magnet and a micro‐gripper to perform a fully robotic ophthalmic minimally invasive surgery on an eye phantom by means of an electromagnetic navigation system.
- Published
- 2021
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35. Performance of a 250L liquid Argon TPC for sub-GeV charged particle identification
- Author
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collaboration, J-PARC T32, Araoka, O., Badertscher, A., Curioni, A., Di Luise, S., Degunda, U., Epprecht, L., Esposito, L., Gendotti, A., Hasegawa, T., Horikawa, S., Kasami, K., Kimura, N., Knecht, L., Kobayashi, T., Lazzaro, C., Lussi, D., Maki, M., Marchionni, A., Maruyama, T., Meregaglia, A., Mitani, T., Nagasaka, Y., Naganoma, J., Naito, H., Narita, S., Natterer, G., Nguyen, K., Nishikawa, K., Okamoto, A., Okamoto, H., Petrolo, F., Resnati, F., Rossi, B., Rubbia, A., Strabel, C., Tanaka, M., Viant, T., Yamanoi, Y., Yorita, K., and Yoshioka, M.
- Subjects
Physics - Instrumentation and Detectors ,High Energy Physics - Experiment - Abstract
We have constructed a liquid Argon TPC detector with fiducial mass of 150 kg as a part of the R&D program of the next generation neutrino and nucleon decay detector. This paper describes a study of particle identification performance of the detector using well-defined charged particles (pions, kaons, and protons) with momentum of ~800 MeV/$c$ obtained at J-PARC K1.1BR beamline., Comment: his paper has been withdrawn by the author due to a crucial problem on the result section
- Published
- 2012
36. First operation and drift field performance of a large area double phase LAr Electron Multiplier Time Projection Chamber with an immersed Greinacher high-voltage multiplier
- Author
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Badertscher, A., Curioni, A., Degunda, U., Epprecht, L., Gendotti, A., Horikawa, S., Knecht, L., Lussi, D., Marchionni, A., Natterer, G., Nguyen, K., Resnati, F., Rubbia, A., and Viant, T.
- Subjects
Physics - Instrumentation and Detectors - Abstract
We have operated a liquid-argon large-electron-multiplier time-projection chamber (LAr LEM-TPC) with a large active area of 76 $\times$ 40 cm$^2$ and a drift length of 60 cm. This setup represents the largest chamber ever achieved with this novel detector concept. The chamber is equipped with an immersed built-in cryogenic Greinacher multi-stage high-voltage (HV) multiplier, which, when subjected to an external AC HV of $\sim$1 kV$_{\mathrm{pp}}$, statically charges up to a voltage a factor of $\sim$30 higher inside the LAr vessel, creating a uniform drift field of $\sim$0.5 kV/cm over the full drift length. This large LAr LEM-TPC was brought into successful operation in the double-phase (liquid-vapor) operation mode and tested during a period of $\sim$1 month, recording impressive three-dimensional images of very high-quality from cosmic particles traversing or interacting in the sensitive volume. The double phase readout and HV systems achieved stable operation in cryogenic conditions demonstrating their good characteristics, which particularly suit applications for next-generation giant-scale LAr-TPCs., Comment: 26 pages, 19 figures
- Published
- 2012
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37. A tagged low-momentum kaon test-beam exposure with a 250L LAr TPC (J-PARC T32)
- Author
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Araoka, O., Badertscher, A., Curioni, A., DiLuise, S., Degunda, U., Epprecht, L., Esposito, L., Gendotti, A., Hasegawa, T., Horikawa, S., Kasami, K., Kimura, N., Knecht, L., Kobayashi, T., Lazzaro, C., Lussi, D., Maki, M., Marchionni, A., Maruyama, T., Meregaglia, A., Mitani, T., Nagasaka, Y., Naganoma, J., Naito, H., Narita, S., Natterer, G., Nishikawa, K., Okamoto, A., Okamoto, H., Petrolo, F., Resnati, F., Rubbia, A., Strabel, C., Tanaka, M., Viant, T., Yamanoi, Y., Yorita, K., and Yoshioka, M.
- Subjects
Physics - Instrumentation and Detectors - Abstract
At the beginning of 2010, we presented at the J-PARC PAC an R$&$D program towards large (100 kton scale) liquid argon TPCs, suitable to investigate, in conjunction with the J-PARC neutrino beam, the possibility of CP violation in the neutrino sector and to search for nucleon decay. As a first step we proposed a test experiment to identify and measure charged kaons, including their decays, in liquid argon. The detector, a 250L LAr TPC, is exposed to charged kaons, in a momentum range of 540-800 MeV/c, in the K1.1BR beamline of the J-PARC slow extraction facility. This is especially important to estimate efficiency and background for nucleon decay searches in the charged kaon mode ($p \rightarrow \bar{\nu} K^+$, etc.), where the kaon momentum is expected to be in the few hundred MeV/c range. A prototype setup has been exposed in the K1.1BR beamline in the fall of 2010. This paper describes the capabilities of the beamline, the construction and setting up of the detector prototype, along with some preliminary results., Comment: 14 pages, 14 figures, to appear in Proc. of 1st International Workshop towards the Giant Liquid Argon Charge Imaging Experiment (GLA2010), Tsukuba (Japan), March 2010
- Published
- 2011
38. ArDM: a ton-scale LAr detector for direct Dark Matter searches
- Author
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ArDM Collaboration, Marchionni, A., Amsler, C., Badertscher, A., Boccone, V., Bueno, A., Carmona-Benitez, M. C., Coleman, J., Creus, W., Curioni, A., Daniel, M., Dawe, E. J., Degunda, U., Gendotti, A., Epprecht, L., Horikawa, S., Kaufmann, L., Knecht, L., Laffranchi, M., Lazzaro, C., Lightfoot, P. K., Lussi, D., Lozano, J., Mavrokoridis, K., Melgarejo, A., Mijakowski, P., Natterer, G., Navas-Concha, S., Otyugova, P., de Prado, M., Przewlocki, P., Regenfus, C., Resnati, F., Robinson, M., Rochet, J., Romero, L., Rondio, E., Rubbia, A., Scotto-Lavina, L., Spooner, N. J. C., Strauss, T., Touramanis, C., Ulbricht, J., and Viant, T.
- Subjects
Physics - Instrumentation and Detectors - Abstract
The Argon Dark Matter (ArDM-1t) experiment is a ton-scale liquid argon (LAr) double-phase time projection chamber designed for direct Dark Matter searches. Such a device allows to explore the low energy frontier in LAr with a charge imaging detector. The ionization charge is extracted from the liquid into the gas phase and there amplified by the use of a Large Electron Multiplier in order to reduce the detection threshold. Direct detection of the ionization charge with fine spatial granularity, combined with a measurement of the amplitude and time evolution of the associated primary scintillation light, provide powerful tools for the identification of WIMP interactions against the background due to electrons, photons and possibly neutrons if scattering more than once. A one ton LAr detector is presently installed on surface at CERN to fully test all functionalities and it will be soon moved to an underground location. We will emphasize here the lessons learned from such a device for the design of a large LAr TPC for neutrino oscillation, proton decay and astrophysical neutrinos searches., Comment: To appear in Proceedings 1st International Workshop towards the Giant Liquid Argon Charge Imaging Experiment (GLA2010), Tsukuba, March 2010
- Published
- 2010
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39. First operation of a double phase LAr Large Electron Multiplier Time Projection Chamber with a two-dimensional projective readout anode
- Author
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Badertscher, A., Curioni, A., Knecht, L., Lussi, D., Marchionni, A., Natterer, G., Resnati, F., Rubbia, A., and Viant, T.
- Subjects
Physics - Instrumentation and Detectors - Abstract
We have previously reported on the construction and successful operation of the novel double phase Liquid Argon Large Electron Multiplier Time Projection Chamber (LAr LEM-TPC). This detector concept provides a 3D-tracking and calorimetric device capable of adjustable charge amplification, a promising readout technology for next-generation neutrino detectors and direct Dark Matter searches. In this paper, we report on the first operation of a LAr LEM-TPC prototype - with an active area of 10$\times$10 cm$^2$ and 21 cm drift length - equipped with a single 1 mm thick LEM amplifying stage and a two dimensional projective readout anode. Cosmic muon events were collected, fully reconstructed and used to characterize the performance of the chamber. The obtained signals provide images of very high quality and the energy loss distributions of minimum ionizing tracks give a direct estimate of the amplification. We find that a stable gain of 27 can be achieved with this detector configuration corresponding to a signal-over-noise ratio larger than 200 for minimum ionizing tracks. The decoupling of the amplification stage and the use of the 2D readout anode offer several advantages which are described in the text., Comment: 25 pages, 17 figures
- Published
- 2010
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40. Stable operation with gain of a double phase Liquid Argon LEM-TPC with a 1 mm thick segmented LEM
- Author
-
Badertscher, A., Curioni, A., Horikawa, S., Knecht, L., Lussi, D., Marchionni, A., Natterer, G., Resnati, F., Rubbia, A., and Viant, T.
- Subjects
Physics - Instrumentation and Detectors - Abstract
In this paper we present results from a test of a small Liquid Argon Large Electron Multiplier Time Projection Chamber (LAr LEM-TPC). This detector concept provides a 3D-tracking and calorimetric device capable of charge amplification, suited for next-generation neutrino detectors and possibly direct Dark Matter searches. During a test of a 3~lt chamber equipped with a 10$\times$10~cm$^2$ readout, cosmic muon data was recorded during three weeks of data taking. A maximum gain of 6.5 was achieved and the liquid argon was kept pure enough to ensure 20~cm drift (O(ppb)~O$_2$ equivalent)., Comment: 7 pages, 6 figures, to appear in Proc. of 1st International Workshop towards the Giant Liquid Argon Charge Imaging Experiment (GLA2010), Tsukuba (Japan), March 2010
- Published
- 2010
- Full Text
- View/download PDF
41. Towards a liquid Argon TPC without evacuation: filling of a 6 m^3 vessel with argon gas from air to ppm impurities concentration through flushing
- Author
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Curioni, A., Epprecht, L., Gendotti, A., Knecht, L., Lussi, D., Marchionni, A., Natterer, G., Resnati, F., Rubbia, A., Coleman, J., Lewis, M., Mavrokoridis, K., McCormick, K., and Touramanis, C.
- Subjects
Physics - Instrumentation and Detectors - Abstract
In this paper we present a successful experimental test of filling a volume of 6 m$^3$ with argon gas, starting from normal ambient air and reducing the impurities content down to few parts per million (ppm) oxygen equivalent. This level of contamination was directly monitored measuring the slow component of the scintillation light of the Ar gas, which is sensitive to {\it all} sources of impurities affecting directly the argon scintillation., Comment: 9 pages, 6 figures, to appear in Proc. 1st International Workshop towards the Giant Liquid Argon Charge Imaging Experiment (GLA2010), Tsukuba, March 2010
- Published
- 2010
- Full Text
- View/download PDF
42. First results on light readout from the 1-ton ArDM liquid argon detector for dark matter searches
- Author
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Amsler, C., Badertscher, A., Boccone, V., Bueno, A., Carmona-Benitez, M. C., Creus, W., Curioni, A., Daniel, M., Dawe, E. J., Degunda, U., Gendotti, A., Epprecht, L., Horikawa, S., Kaufmann, L., Knecht, L., Laffranchi, M., Lazzaro, C., Lightfoot, P. K., Lussi, D., Lozano, J., Marchionni, A., Mavrokoridis, K., Melgarejo, A., Mijakowski, P., Natterer, G., Navas-Concha, S., Otyugova, P., dePrado, M., Przewlocki, P., Regenfus, C., Resnati, F., Robinson, M., Rochet, J., Romero, L., Rondio, E., Rubbia, A., Scotto-Lavina, L., Spooner, N. J. C., Strauss, T., Ulbricht, J., and Viant, T.
- Subjects
Physics - Instrumentation and Detectors - Abstract
ArDM-1t is the prototype for a next generation WIMP detector measuring both the scintillation light and the ionization charge from nuclear recoils in a 1-ton liquid argon target. The goal is to reach a minimum recoil energy of 30\,keVr to detect recoiling nuclei. In this paper we describe the experimental concept and present results on the light detection system, tested for the first time in ArDM on the surface at CERN. With a preliminary and incomplete set of PMTs, the light yield at zero electric field is found to be between 0.3-0.5 phe/keVee depending on the position within the detector volume, confirming our expectations based on smaller detector setups., Comment: 14 pages, 10 figures, v2 accepted for publication in JINST
- Published
- 2010
- Full Text
- View/download PDF
43. The ArDM experiment
- Author
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ArDM Collaboration, Amsler, C., Badertscher, A., Boccone, V., Bourgeois, N., Bueno, A., Carmona-Benitez, M. C., Chorowski, M., Creus, W., Curioni, A., Daw, E., Degunda, U., Dell'Antone, A., Droge, M., Epprecht, L., Haller, C., Haranczyk, M., Horikawa, S., Kaufmann, L., Kisiel, J., Knecht, L., Laffranchi, M., Lagoda, J., Lazzaro, C., Lightfoot, P., Lozano, J., Lussi, D., Maire, G., Mania, S., Marchionni, A., Mavrokoridis, K., Melgarejo, A., Mijakowski, P., Natterer, G., Navas-Concha, S., Otiougova, P., Piotrowska, A., Polinski, J., de Prado, M., Przewlocki, P., Ravat, S., Regenfus, C., Resnati, F., Robinson, M., Rochet, J., Romero, L., Rondio, E., Rubbia, A., Scotto-Lavina, L., Spooner, N., Viant, T., Trawinski, A., Ulbricht, J., and Zalewska, A.
- Subjects
Physics - Instrumentation and Detectors ,Astrophysics - Instrumentation and Methods for Astrophysics ,High Energy Physics - Experiment - Abstract
The aim of the ArDM project is the development and operation of a one ton double-phase liquid argon detector for direct Dark Matter searches. The detector measures both the scintillation light and the ionization charge from ionizing radiation using two independent readout systems. This paper briefly describes the detector concept and presents preliminary results from the ArDM R&D program, including a 3 l prototype developed to test the charge readout system., Comment: Proceedings of the Epiphany 2010 Conference, to be published in Acta Physica Polonica B
- Published
- 2010
44. Giant Liquid Argon Observatory for Proton Decay, Neutrino Astrophysics and CP-violation in the Lepton Sector (GLACIER)
- Author
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Badertscher, A., Curioni, A., Degunda, U., Epprecht, L., Horikawa, S., Knecht, L., Lazzaro, C., Lussi, D., Marchionni, A., Natterer, G., Otiougova, P., Resnati, F., Rubbia, A., Strabel, C., Ulbricht, J., and Viant, T.
- Subjects
Physics - Instrumentation and Detectors - Abstract
GLACIER (Giant Liquid Argon Charge Imaging ExpeRiment) is a large underground observatory for proton decay search, neutrino astrophysics and CP-violation studies in the lepton sector. Possible underground sites are studied within the FP7 LAGUNA project (Europe) and along the JPARC neutrino beam in collaboration with KEK (Japan). The concept is scalable to very large masses., Comment: 4 pages, 1 figure, Contribution to the Workshop "European Strategy for Future Neutrino Physics", CERN, Oct. 2009
- Published
- 2009
45. Operation of a double-phase pure argon Large Electron Multiplier Time Projection Chamber: comparison of single and double phase operation
- Author
-
Badertscher, A., Knecht, L., Laffranchi, M., Lussi, D., Marchionni, A., Natterer, G., Otiougova, P., Resnati, F., Rubbia, A., and Viant, T.
- Subjects
Physics - Instrumentation and Detectors - Abstract
We constructed and operated a double phase (liquid-vapour) pure argon Large Electron Multiplier Time Projection Chamber (LAr LEM-TPC) with a sensitive area of 10x10 cm$^2$ and up to 30 cm of drift length. The LEM is a macroscopic hole electron multiplier built with standard PCB techniques: drifting electrons are extracted from the liquid to the vapour phase and driven into the holes of the LEM where the multiplication occurs. Moving charges induce a signal on the anode and on the LEM electrodes. The orthogonally segmented upper face of the upper LEM and anode permit the reconstruction of X-Y spatial coordinates of ionizing events. The detector is equipped with a Photo Multiplier Tube immersed in liquid for triggering the ionizing events and an argon purification circuit to ensure long drift paths. Cosmic muon tracks have been recorded and further characterization of the detector is ongoing. We believe that this proof of principle represents an important milestone in the realization of very large, long drift (cost-effective) LAr detectors for next generation neutrino physics and proton decay experiments, as well as for direct search of Dark Matter with imaging devices., Comment: 4 pages, 5 figures, Based on a talk given at the 11th Pisa meeting on advanced detectors - Isola d'Elba 26 May 2009
- Published
- 2009
- Full Text
- View/download PDF
46. Development of wavelength shifter coated reflectors for the ArDM argon dark matter detector
- Author
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The ArDM Collaboration, Boccone, V., Lightfoot, P. K., Mavrokoridis, K., Regenfus, C., Amsler, C., Badertscher, A., Bueno, A., Cabrera, H., Carmona-Benitez, M. C., Daniel, M., Daw, E. J., Degunda, U., Dell'Antone, A., Gendotti, A., Epprecht, L., Horikawa, S., Kaufmann, L., Knecht, L., Laffranchi, M., Lazzaro, C., Lussi, D., Lozano, J., Marchionni, A., Melgarejo, A., Mijakowski, P., Natterer, G., Navas-Concha, S., Otyugova, P., de Prado, M., Przewlocki, P., Resnati, F., Robinson, M., Rochet, J., Romero, L., Rondio, E., Rubbia, A., Spooner, N. J. C., Strauss, T., Ulbricht, J., and Viant, T.
- Subjects
Physics - Instrumentation and Detectors - Abstract
To optimise the design of the light readout in the ArDM 1-ton liquid argon dark matter detector, a range of reflector and WLS coating combinations were investigated in several small setups, where argon scintillation light was generated by radioactive sources in gas at normal temperature and pressure and shifted into the blue region by tetraphenyl butadiene (TPB). Various thicknesses of TPB were deposited by spraying and vacuum evaporation onto specular 3M{\small\texttrademark}-foil and diffuse Tetratex{\small\textregistered} (TTX) substrates. Light yields of each reflector and TPB coating combination were compared. Reflection coefficients of TPB coated reflectors were independently measured using a spectroradiometer in a wavelength range between 200 and 650 nm. WLS coating on the PMT window was also studied. These measurements were used to define the parameters of the light reflectors of the ArDM experiment. Fifteen large $120\times 25$ cm$^2$ TTX sheets were coated and assembled in the detector. Measurements in argon gas are reported providing good evidence of fulfilling the light collection requirements of the experiment., Comment: 21 pages, 17 figures
- Published
- 2009
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47. Neutralization of Nogo-A Enhances Synaptic Plasticity in the Rodent Motor Cortex and Improves Motor Learning in Vivo
- Author
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Zemmar, Ajmal, Weinmann, Oliver, Kellner, Yves, Yu, Xinzhu, Vicente, Raul, Gullo, Miriam, Kasper, Hansjörg, Lussi, Karin, Ristic, Zorica, Luft, Andreas R, Rioult-Pedotti, Mengia, Zuo, Yi, Zagrebelsky, Marta, and Schwab, Martin E
- Subjects
Biomedical and Clinical Sciences ,Neurosciences ,Mental Health ,Behavioral and Social Science ,Basic Behavioral and Social Science ,Neurological ,Mental health ,Animals ,Learning ,Long-Term Potentiation ,Male ,Motor Cortex ,Motor Skills ,Myelin Proteins ,Nogo Proteins ,Rats ,Rats ,Sprague-Dawley ,Synapses ,two-photon ,in vivo ,LTP ,motor learning ,Nogo-A ,synaptic plasticity ,Medical and Health Sciences ,Psychology and Cognitive Sciences ,Neurology & Neurosurgery - Abstract
The membrane protein Nogo-A is known as an inhibitor of axonal outgrowth and regeneration in the CNS. However, its physiological functions in the normal adult CNS remain incompletely understood. Here, we investigated the role of Nogo-A in cortical synaptic plasticity and motor learning in the uninjured adult rodent motor cortex. Nogo-A and its receptor NgR1 are present at cortical synapses. Acute treatment of slices with function-blocking antibodies (Abs) against Nogo-A or against NgR1 increased long-term potentiation (LTP) induced by stimulation of layer 2/3 horizontal fibers. Furthermore, anti-Nogo-A Ab treatment increased LTP saturation levels, whereas long-term depression remained unchanged, thus leading to an enlarged synaptic modification range. In vivo, intrathecal application of Nogo-A-blocking Abs resulted in a higher dendritic spine density at cortical pyramidal neurons due to an increase in spine formation as revealed by in vivo two-photon microscopy. To investigate whether these changes in synaptic plasticity correlate with motor learning, we trained rats to learn a skilled forelimb-reaching task while receiving anti-Nogo-A Abs. Learning of this cortically controlled precision movement was improved upon anti-Nogo-A Ab treatment. Our results identify Nogo-A as an influential molecular modulator of synaptic plasticity and as a regulator for learning of skilled movements in the motor cortex.
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- 2014
48. ECONOMIA SOLIDÁRIA: UMA FORMA CONTRA-HEGEMÔNICA DE ORGANIZAÇÃO DO TRABALHO NO CAMPO DA SAÚDE MENTAL
- Author
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MAZARO, Lisabelle Manente, primary and LUSSI, Isabela Aparecida de Oliveira, additional
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- 2023
- Full Text
- View/download PDF
49. Analytical strategies for clinical studies on dental erosive wear
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K. R. Stenhagen, B. Holme, A. B. Tveit, A. Lussi, and T. S. Carvalho
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Erosive tooth wear ,Clinical studies ,Measurements ,Dentistry ,RK1-715 - Abstract
Abstract Background There is a need for analytical techniques for measuring Erosive Tooth Wear (ETW) on natural surfaces in clinical studies. The purpose was to investigate the use of two instruments aimed to assess initial to more advanced stages of ETW. Methods Human premolar enamel samples (2x3mm) (n = 24), were polished flat and mounted in resin cylinders (4 cylinders, 6 samples in each). Part 1: Baseline analyses by White Light Interferometer (WLI), Surface Reflection Intensity (SRI: TableTop and OptiPen) and Surface Hardness (SH). Erosion (1% citric acid (pH 3.6) for 1, 2, 4, 6, 8, 10 min. SRI and SH analyses after every erosion episode and by WLI after 10 min. New indentations were made and enamel loss; was measured by change in indentation depths from toothbrush abrasion (200 g, 60 strokes, 30 s). Another series of 2 × 5 min erosion (totally15 min and 20 min) was analysed with SH and SRI after each erosion, and by WLI (on samples and impressions of samples) after 20 min. Part 2 investigated WLI performance in the interface where initial erosion increases in severity and substance loss occurs. The samples were repolished. Baseline analyses by WLI, SRI (TableTop and OptiPen) and SH. Four cylinders were etched for 1, 2, 4, 8 min respectively and analysed by SRI, SH on samples, and WLI on samples and impressions). Results Part1: SRI decreased from baseline to ~ 6 min etch and increased slightly after abrasion, the two devices correlated well (ICC 0.98 p
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- 2019
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50. Estigmatização: consequências e possibilidades de enfrentamento em Centros de Convivência e Cooperativas
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Adriana Leão and Isabela Aparecida de Oliveira Lussi
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Estigma social ,Saúde pública ,Saúde mental ,Serviços de saúde ,Public aspects of medicine ,RA1-1270 - Abstract
Os efeitos negativos do estigma são um problema significativo em todo o mundo e, para tanto, busca-se aumentar a conscientização e a compreensão das estratégias mais eficazes para combater os estigmas. No âmbito das políticas públicas de saúde, a convivência que promove e intensifica o contato entre as pessoas, com ou sem vulnerabilidades específicas, é intencionalmente promovida pelos Centros de Convivência e Cooperativas (Ceccos). Objetivamos nesse artigo compreender as concepções acerca do processo de estigmatização por meio da visão de profissionais. A análise do discurso resultou em unidades de significação, entre as quais as compreensões em torno de tipos, consequências e possibilidades para o enfrentamento dos estigmas. Não obstante os problemas estruturais e macrossociais presentes, há persistência no trabalho cotidiano diante das possibilidades de transformações observadas no contexto do serviço.
- Published
- 2021
- Full Text
- View/download PDF
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