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15 results on '"Leonard Philippe"'

1. Genetic diversity of Echinococcus multilocularis specimens isolated from Belgian patients with alveolar echinococcosis using EmsB microsatellites analysis

Author

Sacheli, Rosalie, Knapp, Jenny, Pholien, Caroline, Egrek, Sabrina, Léonard, Philippe, Giot, Jean-Baptiste, Delaere, Bénédicte, Blétard, Noella, Gofflot, Stéphanie, Nollevaux, Marie-Cécile, Meunier, Paul, Lovinfosse, Pierre, Pirotte, Benoit, Truyens, Carine, Millon, Laurence, Detry, Olivier, and Hayette, Marie-Pierre

Published
2023
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2. Downregulation of CD94/NKG2A inhibitory receptors on CD8+ T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts

Author

Vaira Dolores, Schaaf-Lafontaine Nicole, Leonard Philippe, Frippiat Frédéric, Jacobs Nathalie, Vandamme Arnaud, Rahmouni Souad, Zeddou Mustapha, Boniver Jacques, and Moutschen Michel

Subjects
Immunologic diseases. Allergy, RC581-607
Abstract

Abstract The CD94/NKG2A heterodimer is a natural killer receptor (NKR), which inhibits cell-mediated cytotoxicity upon interaction with MHC class I gene products. It is expressed by NK cells and by a small fraction of activated CD8+ T lymphocytes. Abnormal upregulation of the CD94/NKG2A inhibitory NKR on cytotoxic T cells (CTLs) could be responsible for a failure of immunosurveillance in cancer or HIV infection. In this study, CD94/NKG2A receptor expression on CD8+ T lymphocytes and NK cells was assessed in 46 HIV-1-infected patients (24 viraemic, 22 aviraemic) and 10 healthy volunteers. The percentage of CD8+ T lymphocytes expressing the CD94/NKG2A inhibitory heterodimer was very significantly decreased in HIV-1-infected patients in comparison with non-infected controls. Within the HIV infected patients, the proportion of CD8+ T lymphocytes and NK cells expressing CD94/NKG2A was higher in subjects with undetectable viral loads in comparison with their viraemic counterparts. No significant difference was detected in the proportion of CD8+ T lymphocytes expressing the activatory CD94/NKG2C heterodimer between the HIV-1 infected patients and the healthy donors, nor between the vireamic and avireamic HIV-1 infected patients. In conclusion, chronic stimulation with HIV antigens in viraemic patients leads to a decreased rather than increased CD94/NKG2A expression on CD8+ T lymphocytes and NK cells.

Published
2007
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6. A patient with HIV infection, cough, asthenia, and fever

Author

Mayasi, Nadine, Chandrikakumari, Kavitha, Mukeba, Didier, Giot, Jean Baptiste, Leonard, Philippe, Hayette, Marie Pierre, Moutschen, Michel, and Frippiat, Frederic

Subjects
Fungi -- Identification and classification, Amphotericin B -- Dosage and administration, HIV patients -- Case studies, Mycoses -- Diagnosis, Mycoses -- Case studies, Health, Health care industry
Published
2007

7. Performance

Author

Leonard, Philippe

Abstract

Philippe Leonard, Performance at the screening The Gamblers: The Zama Zama Miners of Southern Africa, ICI Berlin, 7 January 2019, video recording, mp4, 03:30

Published
2019

8. The Gamblers:The Zama Zama Miners of Southern Africa

Author

Morris, Rosalind, Leonard, Philippe, Collins, Y. Ariadne, Deuber-Mankowsky, Astrid, Berlin, American Academy in, ICI Berlin, Morris, Rosalind, Leonard, Philippe, Collins, Y. Ariadne, Deuber-Mankowsky, Astrid, Berlin, American Academy in, and ICI Berlin

Abstract

Cinematography by Ebrahim Hajee, with underground camera work by Bhekani Mumpande, Prosper Ncube, and Darren Munenge ‘The Gamblers’ is an immersive work that aims to take audience members on a Dantesque journey across the threshold of borders — political as well as geopolitical — into a world beneath the surface of the earth and across the landscape of postindustrial labor in the ruins of South Africa’s gold mines. Made on location and in collaboration with South African cinematographer Ebrahim Hajee and southern African migrant miners Bhekani Mumpande, Prosper Ncube, and Darren Munenge, ‘The Gamblers’ is part of a series of related works, which include the feature-length documentary ‘We are Zama Zama’, produced and directed by Rosalind Morris. This multi-screen work and live edit of high resolution video and 16 mm film, will be followed by a conversation between the work’s director, Rosalind Morris, its video editor and 16 mm film artist, Philippe Leonard, as well as Yolanda Ariadne Collins and Astrid Deuber-Mankowsky. Rosalind Morris is Professor of Anthropology at Columbia University and Andrew W. Mellon Fellow in the Humanities. Her work addresses questions of the relationships between value and violence; aesthetics and the political; the sexualisation of power and desire; and the history of anthropological thought and social theory. Her books include The Returns of Fetishism: Charles de Brosses’s The Worship of Fetish Gods and its Legacies, with Daniel Leonard (Chicago 2017); Accounts and Drawings from Underground: East Rand Proprietary Mines, 1906, with William Kentridge (Chicago and Kolkata 2014); That Which is Not Drawn: William Kentridge in Conversation with Rosalind Morris (Chicago and Kolkata 2013). She is currently fellow at the American Academy in Berlin. Philippe Leonard lives and works in Montreal. His artistic practice focuses on still and moving images, through film, photography, performance, and installations. His theoretical and aesthetic reflect, The Gamblers: The Zama Zama Miners of Southern Africa, screening, ICI Berlin, 7 January 2019

Published
2019

11. Downregulation of CD94/NKG2A inhibitory receptors on CD8+T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts

Author

Zeddou, Mustapha, primary, Rahmouni, Souad, additional, Vandamme, Arnaud, additional, Jacobs, Nathalie, additional, Frippiat, Frédéric, additional, Leonard, Philippe, additional, Schaaf-Lafontaine, Nicole, additional, Vaira, Dolores, additional, Boniver, Jacques, additional, and Moutschen, Michel, additional

Published
2007
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13. FEI, French Institute sponsor joint event

Author

Leonard, Philippe

Subjects
Financial services industry -- Conferences, meetings and seminars, Financial services industry, Banking, finance and accounting industries, Business, Financial Executives International -- Conferences, meetings and seminars
Abstract

FEI and DFCG, the French FEI Institute, hosted a conference in Paris on May 14 titled: 'Old and New World: Working Together.' The objective was to bring together global financial [...]

Published
2004

14. Downregulation of CD94/NKG2A inhibitory receptors on CD8+ T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts.

Author

Zeddou, Mustapha, Rahmouni, Souad, Vandamme, Arnaud, Jacobs, Nathalie, Frippiat, Frédéric, Leonard, Philippe, Schaaf-Lafontaine, Nicole, Vaira, Dolores, Boniver, Jacques, and Moutschen, Michel

Subjects
T cells, HIV infections, CELL-mediated cytotoxicity, KILLER cells, MAJOR histocompatibility complex, DIMERS
Abstract

The CD94/NKG2A heterodimer is a natural killer receptor (NKR), which inhibits cell-mediated cytotoxicity upon interaction with MHC class I gene products. It is expressed by NK cells and by a small fraction of activated CD8+ T lymphocytes. Abnormal upregulation of the CD94/NKG2A inhibitory NKR on cytotoxic T cells (CTLs) could be responsible for a failure of immunosurveillance in cancer or HIV infection. In this study, CD94/NKG2A receptor expression on CD8+ T lymphocytes and NK cells was assessed in 46 HIV-1-infected patients (24 viraemic, 22 aviraemic) and 10 healthy volunteers. The percentage of CD8+ T lymphocytes expressing the CD94/NKG2A inhibitory heterodimer was very significantly decreased in HIV-1-infected patients in comparison with non-infected controls. Within the HIV infected patients, the proportion of CD8+ T lymphocytes and NK cells expressing CD94/NKG2A was higher in subjects with undetectable viral loads in comparison with their viraemic counterparts. No significant difference was detected in the proportion of CD8+ T lymphocytes expressing the activatory CD94/NKG2C heterodimer between the HIV-1 infected patients and the healthy donors, nor between the vireamic and avireamic HIV-1 infected patients. In conclusion, chronic stimulation with HIV antigens in viraemic patients leads to a decreased rather than increased CD94/NKG2A expression on CD8+ T lymphocytes and NK cells. [ABSTRACT FROM AUTHOR]

Published
2007
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15. Downregulation of CD94/NKG2A inhibitory receptors on CD8+ T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts.

Author

Zeddou M, Rahmouni S, Vandamme A, Jacobs N, Frippiat F, Leonard P, Schaaf-Lafontaine N, Vaira D, Boniver J, and Moutschen M

Subjects
Chronic Disease, Down-Regulation, HIV Infections virology, Humans, Killer Cells, Natural metabolism, NK Cell Lectin-Like Receptor Subfamily C, Receptors, Natural Killer Cell, Viral Load, CD8-Positive T-Lymphocytes metabolism, HIV Infections immunology, HIV-1, NK Cell Lectin-Like Receptor Subfamily D metabolism, Receptors, Immunologic metabolism
Abstract

The CD94/NKG2A heterodimer is a natural killer receptor (NKR), which inhibits cell-mediated cytotoxicity upon interaction with MHC class I gene products. It is expressed by NK cells and by a small fraction of activated CD8+ T lymphocytes. Abnormal upregulation of the CD94/NKG2A inhibitory NKR on cytotoxic T cells (CTLs) could be responsible for a failure of immunosurveillance in cancer or HIV infection. In this study, CD94/NKG2A receptor expression on CD8+ T lymphocytes and NK cells was assessed in 46 HIV-1-infected patients (24 viraemic, 22 aviraemic) and 10 healthy volunteers. The percentage of CD8+ T lymphocytes expressing the CD94/NKG2A inhibitory heterodimer was very significantly decreased in HIV-1-infected patients in comparison with non-infected controls. Within the HIV infected patients, the proportion of CD8+ T lymphocytes and NK cells expressing CD94/NKG2A was higher in subjects with undetectable viral loads in comparison with their viraemic counterparts. No significant difference was detected in the proportion of CD8+ T lymphocytes expressing the activatory CD94/NKG2C heterodimer between the HIV-1 infected patients and the healthy donors, nor between the vireamic and avireamic HIV-1 infected patients. In conclusion, chronic stimulation with HIV antigens in viraemic patients leads to a decreased rather than increased CD94/NKG2A expression on CD8+ T lymphocytes and NK cells.

Published
2007
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