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7. SupporTive Care At Home Research (STAHR) for patients with advanced cancer: Protocol for a cluster non-randomized controlled trial

Author

Lee, Dong-Wook, primary, Lee, Sun Young, additional, Yoo, Shin Hye, additional, Kim, Kyae Hyung, additional, Kim, Min-Sun, additional, Shin, Jeongmi, additional, Hwang, In-Young, additional, Hwang, In Gyu, additional, Baek, Sun Kyung, additional, Kim, Do yeun, additional, Kim, Yu Jung, additional, Kang, Beodeul, additional, Lee, Joongyub, additional, and Cho, Belong, additional

Published
2024
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8. The COVID-19 Vaccine Safety Research Center: a cornerstone for strengthening safety evidence for COVID-19 vaccination in the Republic of Korea

Author

Jeong, Na-Young, primary, Park, Hyesook, additional, Oh, Sanghoon, additional, Jung, Seung Eun, additional, Kim, Dong-Hyun, additional, Shin, Hyoung-Shik, additional, Han, Hee Chul, additional, Lee, Jong-Koo, additional, Woo, Jun Hee, additional, Jung, Jaehun, additional, Lee, Joongyub, additional, Shin, Ju-Young, additional, Jung, Sun-Young, additional, Park, Byung-Joo, additional, and Choi, Nam-Kyong, additional

Published
2024
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10. Developing a national surveillance system for stroke and acute myocardial infarction using claims data in the Republic of Korea: a retrospective study

Author

Kim, Tae Jung, primary, Lee, Hak Seung, additional, Kim, Seong-Eun, additional, Park, Jinju, additional, Kim, Jun Yup, additional, Lee, Jiyoon, additional, Song, Ji Eun, additional, Hong, Jin-Hyuk, additional, Lee, Joongyub, additional, Chung, Joong-Hwa, additional, Kim, Hyeon Chang, additional, Shin, Dong-Ho, additional, Lee, Hae-Young, additional, Kim, Bum Joon, additional, Seo, Woo-Keun, additional, Park, Jong-Moo, additional, Lee, Soo Joo, additional, Jung, Keun-Hwa, additional, Kwon, Sun U., additional, Hong, Yun-Chul, additional, Kim, Hyo-Soo, additional, Kang, Hyun-Jae, additional, Lee, Juneyoung, additional, and Bae, Hee-Joon, additional

Published
2024
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11. Coronary Artery Calcification Score and the Progression of Chronic Kidney Disease

Author

Yun, Hae-Ryong, Joo, Young Su, Kim, Hyung Woo, Park, Jung Tak, Chang, Tae Ik, Son, Nak-Hoon, Yoo, Tae-Hyun, Kang, Shin-Wook, Sung, Suah, Lee, Kyu-Beck, Lee, Joongyub, Oh, Kook-Hwan, Han, Seung Hyeok, Ahn, Curie, Oh, Kook-Hwan, Han, Seung Seok, Lee, Hajeong, Koh, Young Ok, So, Jeongok, Ko, Seonui, Lee, Aram, Chae, Dong Wan, Jeong, Jong Cheol, Cho, Hyun Jin, Oh, Jung Eun, Lee, Kyu Jin, Yoo, Tae-Hyun, Choi, Kyu Hun, Han, Seung Hyeok, Park, Jung Tak, Hong, Hui Kyung, You, Ji Young, Lee, Kyu-Beck, Hyun, Young Youl, Kim, Hyun Jung, Kim, Yong-Soo, Kim, Yaeni, Kim, Sol Ji, Chung, Wookyung, Jung, Ji Yong, Jin, Kwon Eun, Sung, Suah, Min, Hyang Ki, Ku, Ja Yung, Kim, Soo Wan, Kwon, Seong, Bae, Eun Hui, Kim, Chang Seong, Kim, Ha Yeon, Oh, Tae Ryom, Choi, Hong Sang, Kim, Minah, Myeong, Chana, Lee, Jeong Ho, Lee, Ji Seon, Kim, Yeong Hoon, Kang, Sun Woo, Kim, Tae Hee, Kim, Yunmi, Oh, Young Eun, Koo, Ja Ryong, Seo, Jang Won, Baek, Seon Ha, Kim, Myung Sun, Chang, Tae Ik, Park, Kyoung Sook, Choi, Aei Kyung, Oh, Yun Kyu, Lee, Jung Pyo, Lee, Jeong Hwan, Park, Jeong Mi, Seong, Eun Young, Heon, Song Sang, Rhee, Harin, Kim, Hyo Jin, Woon, Kim Da, Ji, Seung Hee, Kim, Young Taek, Na, Ki Ryang, Choi, Dae Eun, Ham, Young Rok, Lee, Eu Jin, and Cha, Yoon Jung

Published
2022
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19. Abstract WP40: Development Of The System For National Statistics Of Stroke And Acute Myocardial Infarction Using Claims-based Algorithms In Korea

Author

Kim, Tae Jung, primary, Oh, Hyun-kyung, additional, Lee, Hak Seung, additional, Kim, Seong-eun, additional, Park, Jinju, additional, Kim, Jun Y, additional, Lee, Jiyoon, additional, Song, Jieun, additional, Hong, Jin-Hyuk, additional, Seo, Soon-young, additional, Ahn, Eunmi, additional, Lee, Seon Kui, additional, Lee, Joongyub, additional, Chung, Joong-Wha, additional, Kim, Hyeon Chang, additional, Shin, Dong-ho, additional, Lee, Hae-Young, additional, Kim, Bum Joon, additional, Seo, Woo-Keun, additional, Park, Jong-moo, additional, Lee, Soo Joo J, additional, Jung, Keun-hwa, additional, Kwon, Sun U, additional, Hong, Yun-Chul, additional, Kim, Hyo S, additional, Kang, Hyun-Jae, additional, LEE, JUNEYOUNG, additional, and BAE, Hee-joon, additional

Published
2023
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28. Mayo imaging classification is a good predictor of rapid progress among Korean patients with autosomal dominant polycystic kidney disease: results from the KNOW-CKD study

Author

Park, Hayne Cho, primary, Hong, Yeji, additional, Yeon, Jeong-Heum, additional, Ryu, Hyunjin, additional, Kim, Yong-Chul, additional, Lee, Joongyub, additional, Kim, Yeong Hoon, additional, Chae, Dong-Wan, additional, Chung, WooKyung, additional, Ahn, Curie, additional, Oh, Kook-Hwan, additional, and Oh, Yun Kyu, additional

Published
2022
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30. Intrarenal Renin-Angiotensin System Activation Alters Relationship Between Systolic Blood Pressure and Progression of Chronic Kidney Disease.

Author

Park, Cheol Ho, Kim, Hyung Woo, Park, Jung Tak, Chang, Tae Ik, Yoo, Tae-Hyun, Lee, Joongyub, Sung, Suah, Jung, Ji Yong, Hyun, Young Youl, Oh, Kook-Hwan, Kang, Shin-Wook, and Han, Seung Hyeok

Abstract

Background: Elevated blood pressure and intrarenal renin-angiotensin system activity are closely related to chronic kidney disease (CKD) progression. However, interrelationship between blood pressure and intrarenal renin-angiotensin system activity on the risk of CKD progression is unknown. Methods: We analyzed 2076 participants from the Korean Cohort Study for Outcomes in Patients With CKD. The main exposure was systolic blood pressure (SBP). The urinary angiotensinogen-to-creatinine ratio was stratified according to the median value (3.65 μg/gCr). The primary outcome was a composite kidney outcome of a ≥50% decline in estimated glomerular filtration rate from baseline measurement or initiation of kidney replacement therapy. Results: During 10 550 person-years of follow-up (median, 5.2 years), the composite outcome occurred in 800 (38.5%) participants. In the multivariable cause-specific hazard model, higher SBP was associated with an increased risk of CKD progression. There was a significant interaction between SBP and urinary angiotensinogen-to-creatinine ratio on the risk of the primary outcome (P value for interaction=0.019). In patients with urinary angiotensinogen-to-creatinine <3.65 μg/gCr, the hazard ratios (95% CIs) for SBP 120 to 129, 130 to 139, and ≥140 mmHg were 1.46 (1.07–1.99), 1.71 (1.25–2.35), and 2.40 (1.73–3.32), respectively, compared with SBP <120 mmHg. However, these associations were not observed in patients with urinary angiotensinogen-to-creatinine ≥3.65 μg/gCr. Conclusions: In this prospective CKD cohort, higher SBP was associated with CKD progression when urinary angiotensinogen levels were low, while this association was not seen when urinary angiotensinogen levels were high. This finding suggests that intrarenal renin-angiotensin system activity may modify the relationship between SBP and adverse kidney outcome. [ABSTRACT FROM AUTHOR]

Published
2023
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36. Association of coronary artery calcium with adverse cardiovascular outcomes and death in patients with chronic kidney disease: results from the KNOW-CKD

Author

Jung, Chan-Young, primary, Yun, Hae-Ryong, additional, Park, Jung Tak, additional, Joo, Young Su, additional, Kim, Hyung Woo, additional, Yoo, Tae-Hyun, additional, Kang, Shin-Wook, additional, Lee, Joongyub, additional, Chae, Dong-Wan, additional, Chung, Wookyung, additional, Kim, Yong-Soo, additional, Oh, Kook-Hwan, additional, and Han, Seung Hyeok, additional

Published
2022
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37. Association Between Left Ventricular Geometry and Renal Outcomes in Patients With Chronic Kidney Disease: Findings From Korean Cohort Study for Outcomes in Patients With Chronic Kidney Disease Study

Author

Suh, Sang Heon, primary, Oh, Tae Ryom, additional, Choi, Hong Sang, additional, Kim, Chang Seong, additional, Bae, Eun Hui, additional, Oh, Kook-Hwan, additional, Lee, Joongyub, additional, Jung, Ji Yong, additional, Lee, Kyu-Beck, additional, Ma, Seong Kwon, additional, and Kim, Soo Wan, additional

Published
2022
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38. Additional file 1 of Treatment patterns and cost of exacerbations in patients with chronic obstructive pulmonary disease using multiple inhaler triple therapy in South Korea

Author

Lee, Chang-Hoon, Kim, Mi-Sook, Yeo, See-Hwee, Rhee, Chin-Kook, Park, Heung-Woo, Yang, Bo-Ram, Lee, Joongyub, Cho, Eun-Yeong, Xu, Xiaomeng, Navarro Rojas, Aldo Amador, Shantakumar, Sumitra, Milea, Dominique, and Choi, Nam-Kyong

Abstract

Additional file 1. Table S1. ICD-10-CM codes for Charlson Comorbidities Index-related comorbidities. Table S2. ICD-10 codes for Elixhauser comorbidities. Fig. S1. Illustration of PDC calculation and sensitivity analysis. Fig. S2. Adherence to and persistence with MITT of patients with COPD.

Published
2022
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39. Association of coronary artery calcium with adverse cardiovascular outcomes and death in patients with chronic kidney disease: results from the KNOW-CKD.

Author

Jung, Chan-Young, Yun, Hae-Ryong, Park, Jung Tak, Joo, Young Su, Kim, Hyung Woo, Yoo, Tae-Hyun, Kang, Shin-Wook, Lee, Joongyub, Chae, Dong-Wan, Chung, Wookyung, Kim, Yong-Soo, Oh, Kook-Hwan, and Han, Seung Hyeok

Subjects
CORONARY artery calcification, CHRONIC kidney failure, CARDIOVASCULAR disease related mortality, CHRONICALLY ill, MAJOR adverse cardiovascular events
Abstract

Background In East Asian countries, patients with chronic kidney disease (CKD) have lower cardiovascular risk profiles and experience fewer cardiovascular events (CVEs) than those in Western countries. Thus the clinical predictive performance of well-known risk factors warrants further testing in this population. Methods The KoreaN cohort study for Outcome in patients With Chronic Kidney Disease (KNOW-CKD) is a multicenter, prospective observational study. We included 1579 participants with CKD G1–G5 without kidney replacement therapy between 2011 and 2016. The main predictor was the coronary artery calcium score (CACS). The primary outcome was a composite of nonfatal CVEs or all-cause mortality. Secondary outcomes included 3-point major adverse cardiovascular events (MACEs; the composite of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke), all CVEs and all-cause mortality. Results During a median follow-up of 5.1 years, a total of 123 primary outcome events occurred (incidence rate 1.6/100 person-years). In the multivariable Cox model, a 1-standard deviation log increase in the CACS was associated with a 1.67-fold [95% confidence interval (CI), 1.37–2.04] higher risk of the primary outcome. Compared with a CACS of 0, the hazard ratio associated with a CACS >400 was 4.89 (95% CI 2.68–8.93) for the primary outcome. This association was consistent for secondary outcomes. Moreover, inclusion of the CACS led to modest improvements in prediction indices of the primary outcome compared with well-known conventional risk factors. Conclusions In Korean patients with CKD, the CACS was independently associated with adverse cardiovascular outcomes and all-cause death. The CACS also showed modest improvements in prediction performance over conventional cardiovascular risk factors. [ABSTRACT FROM AUTHOR]

Published
2023
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40. Association of High Serum Adiponectin Level With Adverse Cardiovascular Outcomes and Progression of Coronary Artery Calcification in Patients With Pre-dialysis Chronic Kidney Disease

Author

Suh, Sang Heon, primary, Oh, Tae Ryom, additional, Choi, Hong Sang, additional, Kim, Chang Seong, additional, Lee, Joongyub, additional, Oh, Yun Kyu, additional, Jung, Ji Yong, additional, Lee, Kyu-Beck, additional, Oh, Kook-Hwan, additional, Ma, Seong Kwon, additional, Bae, Eun Hui, additional, and Kim, Soo Wan, additional

Published
2022
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41. Real-world Treatment Patterns, Outcomes, and Healthcare Resource Utilization in Newly Treated Korean Patients With Asthma: A Retrospective Cohort Study

Author

Choi, Nam-Kyong, primary, Shantakumar, Sumitra, additional, Kim, Mi-Sook, additional, Lee, Chang-Hoon, additional, Cheng, Wendy Y, additional, Bobbili, Priyanka, additional, Yang, Bo Ram, additional, Lee, Joongyub, additional, Hinds, David, additional, Duh, Mei Sheng, additional, Korves, Caroline, additional, and Park, Heung-Woo, additional

Published
2022
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42. Quality of life in patients with diabetic nephropathy: findings from the KNOW-CKD (Korean Cohort Study for Outcomes in Patients with Chronic Kidney Disease) cohort

Author

Kim, Hyunsuk, primary, Lee, Joongyub, additional, Choi, Gwang Ho, additional, Jeong, Hae Min, additional, Kim, Seok hyung, additional, Gu, Jae Eon, additional, Yoo, Jeong-Ju, additional, Han, Miyeun, additional, Kim, Hyo-Jin, additional, Sung, Su-Ah, additional, Han, Seung Hyeok, additional, Kim, Yeong Hoon, additional, Yoon, Jong-Woo, additional, Heo, Jongho, additional, and Oh, Kook-Hwan, additional

Published
2021
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44. Development of predictive score for post-transplant survival based on pre-transplant recipient characteristics

Author

Yang Jaeseok, Lee Joongyub, and Koo Tai Yeon

Subjects
medicine.medical_specialty, business.industry, Internal medicine, Transplant recipient, Medicine, business, medicine.disease, Kidney transplantation
Abstract

The new kidney allocation system in the United States has introduced longevity matching, which gives priority to allocating the best quality organs to wait-listed candidates with the longest predicted survival for the efficient utilization of organs that are of limited availability. The estimated post-transplant survival (EPTS) score was developed in the United States to risk-stratify all wait-listed patients. However, prognostic indices used in Western countries were derived from data that may be different for Korea and do not necessarily reflect prognostic values for Korean deceased donor kidney transplantation. Prognostic indices for Korean wait-listed candidates therefore need to be developed from Korean data.We analyzed 6,731 adult solitary kidney transplant patients for candidate risk prediction using the national data from the Korean Network for Organ Sharing (KONOS) and National Health Insurance Data Sharing Service (NHISS). Cox regression analysis was used to model the risk of patient death.The Korean EPTS (K-EPTS) score was developed based on four recipient parameters (age, diabetes mellitus, hepatitis C virus, and duration of dialysis) that showed a significant association with post-transplant survival. K-EPTS scores showed good discrimination (C-statistics 0.690; 95% confidence interval, 0.666-0.715). Moreover, the ability of the K-EPTS score to discriminate patient survival was better than that of the EPTS according to the criteria of the United Network for Organ Sharing (US-EPTS) score (P0.001).The K-EPTS score, which was developed based on Korean national data, is expected to contribute to the assessment of recipient prognosis and efficient utilization of deceased donor kidneys.

Published
2021

46. Effects of blood urea nitrogen independent of the estimated glomerular filtration rate on the development of anemia in non-dialysis chronic kidney disease: The results of the KNOW-CKD study

Author

Kim, Hyo Jin, primary, Kim, Tae Eun, additional, Han, Miyeun, additional, Yi, Yongin, additional, Jeong, Jong Cheol, additional, Chin, Ho Jun, additional, Song, Sang Heon, additional, Lee, Joongyub, additional, Lee, Kyu-Beck, additional, Sung, Suah, additional, Han, Seung Hyeok, additional, Seong, Eun Young, additional, Ahn, Curie, additional, Oh, Kook-Hwan, additional, and Chae, Dong-Wan, additional

Published
2021
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48. Metabolic Acidosis Is an Independent Risk Factor of Renal Progression in Korean Chronic Kidney Disease Patients: The KNOW-CKD Study Results

Author

Kim, Hyo Jin, primary, Ryu, Hyunjin, additional, Kang, Eunjeong, additional, Kang, Minjung, additional, Han, Miyeun, additional, Song, Sang Heon, additional, Lee, Joongyub, additional, Jung, Ji Yong, additional, Lee, Kyu-Beck, additional, Sung, Suah, additional, Seong, Eun Young, additional, Ahn, Curie, additional, and Oh, Kook-Hwan, additional

Published
2021
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49. Low bone mineral density is associated with coronary arterial calcification progression and incident cardiovascular events in patients with chronic kidney disease

Author

Kim, Hyoungnae, primary, Lee, Joongyub, additional, Lee, Kyu-Beck, additional, Kim, Yeong-Hoon, additional, Hong, Namki, additional, Park, Jung Tak, additional, Han, Seung Hyeok, additional, Kang, Shin-Wook, additional, Choi, Kyu Hun, additional, Oh, Kook-Hwan, additional, and Yoo, Tae-Hyun, additional

Published
2021
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