197 results on '"Lameness in dogs"'
Search Results
2. Spontaneous Osteoarthritis in Dogs - Clinical Effects of Single and Multiple Intra-articular Injections of Hyaluronic Acid.
- Author
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Lee, Eunbee, Mun-Ik Lee, Sehoon Kim, and Byung-Jae Kang
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OSTEOARTHRITIS in dogs , *HYALURONIC acid , *SYNOVIAL fluid , *DISEASE progression , *LAMENESS in dogs - Abstract
Background: The treatments of osteoarthritis (OA) are commonly conservative and multimodal to relieve pain and improve movement. Intra-articular injection of hyaluronic acid (IAHA) has been studied as a treatment option for OA in dogs. IAHA helps restore the viscoelasticity of the synovial fluid and relieves the clinical symptoms of OA. However, the efficacy of IAHA in dogs is still a controversial subject. This study aims to confirm the IAHA effect in dogs with spontaneous OA and to compare the effectiveness depending on the number of injections. Materials, Methods & Results: Thirty dogs with spontaneous OA were assigned to a single injection group (n=17) and a 3-weekly injections group (n=13). Dogs weighing less than 10 kg were injected 1 mL of HA to the OA joint, and more than 10 kg dogs were injected 2 mL of HA. In the case of the 3-weekly injections group, the same amount was administered 3 times at 1-week intervals. After the injection, physical and orthopedic examinations were performed to check for complications. Radiographic OA score was evaluated before and 3 months after the injection to confirm and to evaluate the progression of OA. Clinical symptom evaluations were performed on pre-injection, 1-, 2-, and 3-months post-injection. They consisted of the clinical lameness score by veterinarians and Canine Brief Pain Inventory (CBPI) by owners. Results were compared with unpaired t-test, repeated-measures ANOVA with Tukey's or Sidak's multiple comparison test, or Wilcoxon test, with P < 0.05. Patients had a median age of 9 years (range 3 to 16 years) and a bodyweight of 4.8 kg (range 2 to 48 kg). No systemic side effects or major complications were detected during the trial period. IAHA produced temporary pain and discomfort in 6 cases. There was no change in the radiographic OA score before and 3 months after injections in both groups, and the difference between groups was not confirmed. In both groups, the clinical lameness score significantly decreased at 1, 2, 3 months after injection compared with pre-injection. The score was lower at 3 months after the injection than at 1 month. The clinical lameness score had no significant difference between the groups. Similarly, CBPI was all decreased in the single injection group and 3-weekly injections group compared to pre-injection, and the score at 3 months post-injection was lower than at 1 month. No significant differences between the groups were found in CBPI. Discussion: Most studies on the efficacy of IAHA in canine OA have been conducted using an experimental model, so studies on spontaneous canine OA are insufficient. This study confirmed that IAHA improves clinical symptoms such as pain relief and movement improvement in spontaneous OA dogs using CBPI and clinical lameness score. In order to confirm the optimal IAHA protocol, a single IAHA and 3-weekly IAHA were compared. The result shows that clinical symptoms improved in both single and 3-weekly injections groups, but no significant difference was confirmed during the 3-month study period. These findings may suggest that a single IAHA may have a similar effect to multiple IAHA, and repeated injections are unnecessary. In humans and canine OA models, it is reported that the effect of IAHA was maintained for 6 months. This study showed that the effect of IAHA was maintained for 3 months study period and that clinical symptoms improved at 3 months than at 1 month. In conclusion, these findings suggested that IAHA improves clinical symptoms in dogs with spontaneous OA, and a single IAHA showed a similar effect to 3 weekly IAHA. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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3. Comparison between Novice and Experienced Surgeons Performing Corrective Osteotomy with Patient-Specific Guides in Dogs Based on Resulting Position Accuracy.
- Author
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Yoon Ho Rho, Cheong Woon Cho, Chang Hun Ryu, Je Hun Lee, Seong Mok Jeong, and Hae Beom Lee
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OSTEOTOMY ,LAMENESS in dogs ,COMPUTER-aided design ,THREE-dimensional printing ,ARTHRODESIS - Abstract
Corrective osteotomy has been applied to realign and stabilize the bones of dogs with lameness. However, corrective osteotomy for angular deformities requires substantial surgical experience for planning and performing accurate osteotomy. Three-dimensional printed patient-specific guides (3D-PSGs) were developed to overcome perioperative difficulties. In addition, novices can easily use these guides for performing accurate corrective osteotomy. We compared the postoperative results of corrective osteotomy accuracy when using 3D-PSGs in dogs between novice and experienced surgeons. We included eight dogs who underwent corrective osteotomy: three angular deformities of the radius and ulna, three distal femoral osteotomies, one center of rotational angle-based leveling osteotomy, and one corrective osteotomy with stifle arthrodesis. All processes, including 3D bone modeling, production of PSGs, and rehearsal surgery were carried out with computer-aided design software and a 3D-printed bone model. Pre- and postoperative positions following 3D reconstruction were evaluated by radiographs using the 2D/3D registration technique. All patients showed clinical improvement with satisfactory alignment and position. Postoperative accuracy evaluation revealed no significant difference between novice and experienced surgeons. PSGs are thought to be useful for novice surgeons to accurately perform corrective osteotomy in dogs without complications. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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4. Evaluation of a genicular axial pattern flap to repair large cutaneous tibial defects in two dogs.
- Author
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Ober, Ciprian, Taulescu, Marian, Pestean, Cosmin, Melega, Iulia, Oana, Liviu, Milgram, Joshua, and McCartney, William
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DIAGNOSIS of dog diseases , *TIBIA physiology , *LAMENESS in dogs , *LABRADOR retriever , *FIBROSARCOMA - Abstract
Background: Clinical outcome after cutaneous reconstruction using genicular artery flaps has not been reported. Major cutaneous defects of the pelvic limb between the stifle and hock are frequent in dogs and closure is difficult due to lack of available skin from immediately adjacent areas. Case presentation: Here we report the first two clinical cases successfully managed by genicular axial pattern flap closure. A 2-year-old 38 kg (83.77-lb) intact male Labrador Retriever and a 14-year-old 42 kg (92.59-lb) spayed mixed breed female dog were admitted for the management of large skin defects in the lateral tibiotarsal joint. One defect was the result of a fibrosarcoma removal in the Labrador dog and the other defect was a chronic large wound caused by a car accident in the mixed breed female dog. Both defects were reconstructed by using genicular flaps. The bed of the wound in mixed breed dog was surgically debrided and underwent open wound management until a proper granulation tissue bed was formed before reconstruction. The skin defect in the Labrador dog was covered immediately after tumor removal. After surgery both dogs were bearing weight on the limbs normally. Small area of dehiscence occurred in both dogs 2 weeks after surgery. At follow-up examination one month after surgery, the surgical wound of the Labrador retriever still had a small area of dehiscence. Two months after surgery, the wound of the mixed breed dog was completely healed, covered with hair and no lameness was observed. Conclusion: Findings suggested that genicular axial pattern flap is a good option for reconstruction of large cutaneous defects of the lateral aspects of the tibia in dogs. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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5. Single-day and multiday repeatability of stance analysis results for dogs with hind limb lameness.
- Author
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Wilson, Megan L., Roush, James K., and Renberg, Walter C.
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LAMENESS in dogs , *BODY weight , *VETERINARY medicine , *LOCOMOTOR control , *HIP surgery - Abstract
OBJECTIVE To assess single-day and multiday repeatability of weight distribution (stance) data obtained with a commercial analyzer for dogs with naturally occurring hind limb lameness. ANIMALS 46 dogs (15 and 31 for single-day and multiday trials, respectively). PROCEDURES For single-day trials, 5 to 10 measurements/trial were collected to determine body weight (BW), weight distribution on each limb, and forelimb and hind limb symmetry indices (Sis). The dog was removed from the room and returned immediately; 5 trials were performed. For multiday trials, measurements were performed in the same manner on 2 sequential days. Data were compared among trials (single-day measurements) and between days (multiday measurements). Repeatability (correlation coefficients and Lin concordance correlation coefficients [LCCCs]) and variability (coefficients of variation [CVs]) were assessed. RESULTS In single-day trials, B W (r = 0.999), weight distribution on the lame hind limb (r = 0.915) and contralateral hind limb (r = 0.948), and hind limb SI (r = 0.964) were each significantly correlated among trials. In multiday trials, BW results were similar; weight distribution on the lame hind limb and contralateral hind limb and hind limb SI were each less closely but still significantly correlated between days. The LCCCs were highest for BW, weight distribution on the contralateral hind limb, and hind limb SI in single-day trials and for B W and weight bearing on the contralateral and lame hind limbs in multiday trials. The CVs were lowest for B W and highest for forelimb SI in both trial types. CONCLUSIONS AND CLINICALRELEVANCE The analyzer used allowed repeatable measurement of B W and weight distribution on the hind limbs of dogs with hind limb lameness. Measurement of forelimb stance variables was not repeatable in this group of dogs. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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6. Simultaneous fluoroscopic-guided tibial plateau leveling and fracture reduction for the concurrent treatment of chronic cranial cruciate ligament tear and comminuted diaphyseal fracture of the tibia and fibula in a dog.
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Petazzoni, Massimo and Buiatti, Michela
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LAMENESS in dogs , *FLUOROSCOPY , *PERIODIC health examinations , *TIBIAL plateau fractures ,FIBULA injuries - Abstract
CASE DESCRIPTION A 12-year-old obese spayed female American Staffordshire Terrier was admitted for evaluation of acute non-weight-bearing lameness of the right pelvic limb attributed to motor vehicle-related trauma that occurred 2 hours previously. The owners reported a chronic, progressive weight-bearing lameness of the right pelvic limb secondary to a complete cranial cruciate ligament (CrCL) rupture that was diagnosed 6 months previously. They had declined surgery for CrCL repair because of the advanced age of the dog. CLINICAL FINDINGS Physical examination revealed a 2-cm skin wound on the craniomedial aspect of the midtibial region. The dog had non-weight-bearing lameness of the right pelvic limb with associated muscle atrophy and signs of pain on palpation of the right tibia. Radiography was performed, and tibial and fibular fractures were diagnosed. The fractures were classified as second-degree open, severely comminuted, complex nonreconstructible diaphyseal fractures. TREATMENT AND OUTCOME The tibial fracture and CrCL rupture were treated by closed reduction and simultaneous tibial plateau leveling by indirect fluoroscopic-guided alignment, plus stabilization with a monoplanar external fixator. The 2 main tibial fragments were manipulated via the frame clamps to restore limb length and alignment and tibial plateau slope. Both the tibial and fibular fractures healed within 16 weeks after surgery. At the 2-month recheck examination after implant removal, the dog was walking normally. CLINICAL RELEVANCE Simultaneous treatment of tibial fracture and CrCL rupture with unilateral external fixation was successful in this dog and may be helpful in similar cases. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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7. Comparison of three walkway cover types for use during objective canine gait analysis with a pressure-sensitive walkway.
- Author
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Kieves, Nina R., Hart, Juliette L., Evans, Richard B., and Duerr, Felix M.
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LAMENESS in dogs , *CANIDAE , *CANINE hip dysplasia , *POLYVINYL chloride , *MUSCULOSKELETAL system diseases - Abstract
OBJECTIVE To compare the effects of 3 walkway cover types on temporospatial and ground reaction force measurements of dogs during gait analysis with a pressure-sensitive walkway (PSW). ANIMALS 35 client- and staff-owned dogs (25 nonlame and 10 lame). PROCEDURES In a crossover study design, all dogs were evaluated at a comfortable walk on a PSW to which 3 cover types (a 0.32-cm-thick corrugated vinyl mat or a 0.32- o r 0.64-cm-thick polyvinyl chloride yoga mat) were applied in random order. Temporospatial and ground reaction force measurements were obtained and compared among cover types within the nonlame and lame dog groups. RESULTS Several variables, including maximum peak pressure, maximum force (absolute and normalized as a percentage of body weight), and vertical impulse (absolute and normalized) differed significantly in most comparisons among cover types for both nonlame and lame dogs. There was no significant difference in maximum force values between the 0.32-cm-thick corrugated vinyl and 0.64-cm-thick polyvinyl chloride cover types fo r both nonlame and lame dogs. CONCLUSIONS AND CLINICAL RELEVANCE To the authors' knowledge, the cover type used during data collection with a PSW is rarely provided in published reports on this topic. The findings in this study suggested that to ensure that PSW data for dogs are collected in a standardized manner, the same cover type should be used during followup visits to evaluate clinical outcomes, fo r the duration of research studies, and at all locations for multi-institutional studies. The cover type should be specified in future PSW studies to allow direct comparisons of findings between studies. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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8. Occurrence of canine hip dysplasia, cranial cruciate ligament rupture and patellar luxation in dogs in a retrospective study of 100 orthopedic cases.
- Author
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Maciel, Mônica, de Oliveira Reusing, Mhayara Samile, Villanova Junior, José Ademar, Iobe Tasqueti, Ubirajara, and Henrique Weber, Saulo
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CANINE hip dysplasia ,CRUCIATE ligament injuries ,PATELLA dislocation ,ORTHOPEDICS ,LAMENESS in dogs - Abstract
Copyright of Revista Acadêmica: Ciência Animal is the property of Revista Academica: Ciencia Animal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
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9. Biphasic malignant melanoma adenocarcinoma in the digit of a dog.
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Needle, David B., Iglikova, Olga, and Miller, Andrew D.
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MELANOMA ,CANCER in dogs ,LAMENESS in dogs - Abstract
A 7-y-old Black Russian Terrier dog was evaluated for chronic lameness of the right forelimb and concurrent weight loss. Clinical examination revealed a pigmented mass arising from digit 4 of the right forelimb; the digit was amputated and submitted for histologic evaluation. Histologically, the neoplasm was composed of ill-defined streams, sheets, and clusters of melanocytes admixed with a distinct population of malignant epithelial cells forming glands and nests. The diagnosis was a biphasic malignant melanoma adenocarcinoma, a rarely reported neoplasm in human medicine that has not been described in veterinary medicine, to our knowledge. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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10. Influence of trial repetition on lameness during force platform gait analysis in a heterogeneous population of clinically lame dogs each trotting at its preferred velocity.
- Author
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Mickelson, Megan A., Thao Vo, Piazza, Alexander M., Nemke, Brett W., Muir, Peter, and Volstad, Nicola J.
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LAMENESS in dogs , *GAIT disorders , *GROUND reaction forces (Biomechanics) , *AGILITY trials for dogs , *DOG diseases - Abstract
OBJECTIVE To determine variance effects influencing ground reaction forces (GRFs) in a heterogeneous population of lame dogs during trotting. ANIMALS 30 client-owned dogs with thoracic limb lameness and 31 dogs with pelvic limb lameness. PROCEDURES GRFs, velocity, height at the dorsal aspect of the scapulae (ie, withers), and shoulder height were obtained. Each dog was trotted across a force platform at its preferred velocity. Variance effects for 12 velocity and associated relative velocity (V*) ranges were examined. RESULTS Individual dog, velocity, V*, and limb significantly influenced GRFs. Withers height V* ranges were associated with small variance in GRFs, but all absolute and V* ranges were associated with significant effects for all 4 limbs and both types of lameness. Significant changes in lame limb GRFs and velocity in ipsilateral trials in dogs with thoracic limb and pelvic limb lameness were evident with trial repetition. Withers height V* range of 0.55 to 0.93 captured a large proportion of trials (> 90%) in dogs with thoracic limb or pelvic limb lameness, with limited effects on peak vertical force and vertical impulse. CONCLUSIONS AND CLINICAL RELEVANCE Trial repetition caused alterations to GRFs and subject velocity that may have confounded assessment of lameness, which supported the concept that a priori selection of a velocity or V* range for force platform gait analysis should use a range that captures valid trials efficiently while minimizing GRF variance. These ranges typically would span the preferred velocity of subject dogs, such as withers height V* of 0.55 to 0.93. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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11. Medical infrared imaging and orthostatic analysis to determine lameness in the pelvic limbs of dogs.
- Author
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Garcia, Erika Fernanda V., Loughin, Catherine A., Marino, Dominic J., Sackman, Joseph, Umbaugh, Scott E., Jiyuan Fu, Subedi, Samrut, Lesser, Martin L., Akerman, Meredith, and Schossler, João Eduardo W.
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LAMENESS in dogs , *PELVIC diseases , *PELVIC radiography , *ORTHOSTATIC intolerance , *DIAGNOSTIC imaging , *DIAGNOSIS - Abstract
Subtle lameness makes it difficult to ascertain which is the affected limb. A study was conducted to investigate a change in the thermal pattern and temperature of the thermal image of the paw print in a lame pelvic limb compared to a non-lame pelvic limb of dogs confirmed by orthostatic analysis. Fourteen client owned dogs with a unilateral pelvic limb lameness and 14 healthy employee dogs were examined and the pelvic limbs radiographed. Thermal images of the paw print were taken after each dog was kept in a static position on a foam mat for 30 seconds. Average temperatures and thermographic patterns were analyzed. Analysis was performed in a static position. The asymmetry index for each stance variable and optimal cutoff point for the peak vertical force and thermal image temperatures were calculated. Image pattern analysis revealed 88% success in differentiating the lame group, and 100% in identifying the same thermal pattern in the healthy group. The mean of the peak vertical force revealed a 10.0% difference between the left and right pelvic limb in healthy dogs and a 72.4% between the lame and non-lame limb in the lame dog group. Asymmetry index analysis revealed 5% in the healthy group and 36.2% in the lame group. The optimal cutoff point for the peak vertical force to determine lameness was 41.77% (AUC = 0.93) and for MII 0.943% (AUC = 0.72). The results of this study highlight the change in the thermal pattern of the paw print in the lame pelvic limb compared to a non-lame pelvic limb in the lame group and the healthy group. Medical infrared imaging of the paw prints can be utilized to screen for the lame limb in dogs. [ABSTRACT FROM AUTHOR]
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- 2017
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12. Atypical radiographic features of multiple myeloma in a dog: a case report.
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SUNG, S., LIM, S., OH, H., KIM, K., CHOI, Y., and LEE, K.
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CANCER in dogs , *MULTIPLE myeloma diagnosis , *VETERINARY radiography , *LAMENESS in dogs , *CASTRATION - Abstract
A 12-year-old castrated male miniature pinscher dog presented with right forelimb lameness. An expansile osteolytic lesion of the right humerus was conspicuous on right forelimb radiographs. Thoracic and abdominal radiographs showed multiple lytic bone lesions on the right scapula, ribs, vertebrae, femurs and pelvis. Additionally, an expansile osteolytic lesion was observed in two thoracic vertebrae and two ribs. Many plasma cells were identified on fine-needle aspiration of the right humerus expansile osteolytic lesion, and monoclonal gammopathy consistent with multiple myeloma was confirmed on serum protein electrophoresis. The expansile osteolytic lesion, an extraordinary radiographic feature of multiple myeloma in dogs, should be considered as a possible radiographic finding of multiple myeloma. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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13. Single oblique osteotomy for correction of antebrachial angular and torsional deformities in a dog.
- Author
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Sun-Young Kim, Snowdon, Kyle A., and DeCamp, Charles E.
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LAMENESS in dogs , *OSTEOTOMY , *ORTHOPEDIC surgery , *VETERINARY surgery , *FORELIMB abnormalities - Abstract
CASE DESCRIPTION A 9-month-old 4.6-kg (10.1-lb) spayed female Shih Tzu was examined for a 4-week history of left forelimb lameness. CLINICAL FINDINGS Moderate left forelimb lameness was present when weight bearing, accompanied by buckling of the left carpal joint and moderate signs of pain with hyperextension of the elbow joint. A 32° angular deformity of the left radius in a 45° craniomedial oblique plane (equivalent to 23° valgus and 23° procurvatum) and a 55° external torsional deformity were measured on 3-D reconstructed CT images. Humeroulnar incongruity of the left elbow joint was also evident. Single oblique osteotomy (SOO) and dynamic proximal ulnar osteotomy were recommended. TREATMENT AND OUTCOME Creation of a 3-D printed bone model from reconstructed CT images aided surgical planning. The SOO was located 45° medial to the sagittal plane of the left radius at the level of the center of rotation of angulation. The SOO was oriented 32° distolaterally from the transverse plane of the radius and traversed the left ulna. The bones were rotated along the osteotomy into grossly proper alignment and stabilized with a plate and bone screws. Dynamic proximal ulnar osteotomy was then performed. Six months after surgery, radiographs showed remodeling at the SOO site and the lameness had resolved. The owners expressed satisfaction with the outcome. CLINICAL RELEVANCEIn dogs with angular and torsional long bone deformities, SOO may be a viable alternative to wedge osteotomies. The SOO simultaneously addressed angular and torsional deformities without bone loss and provided rigid internal fixation. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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14. INCOMPLETE OSSIFICATION OF THE HUMERAL CONDYLE (IOHC) IN A THREE-YEAR-OLD GERMAN SHEPHERD.
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Marko, MITROVIĆ, Yves, SAMOY, Mirjana, LAZAREVIĆ MACANOVIĆ, Henri, van BREE, and Ingrid, GIELEN
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COMPUTED tomography ,DOG diseases ,LAMENESS in dogs ,OSSIFICATION ,BONES ,ORTHOPEDICS - Abstract
Copyright of Veterinarski Glasnik is the property of Veterinarski Glasnik and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2017
- Full Text
- View/download PDF
15. SYSTEMIC LUPUS ERYTHEMATOSUS - DIAGNOSTIC AND TREATMENT CHALLENGES.
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Mirna, BRKLJAČIĆ, Filip, KAJIN, Marin, TORTI, Ines, JOVIĆ, Ivana, KIŠ, Iva, ŠMIT, Martina, CRNOGAJ, and Vesna, MATIJATKO
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DOG diseases ,LAMENESS in dogs ,VETERINARY medicine ,AUTOIMMUNE diseases ,IMMUNOGLOBULINS - Abstract
Copyright of Veterinarski Glasnik is the property of Veterinarski Glasnik and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2017
- Full Text
- View/download PDF
16. Surgical management of pivot-shift phenomenon in a dog.
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Knight, Rebekah C., Thomson, David G., and Danielski, Alan
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DOG diseases , *LAMENESS in dogs , *OSTEOTOMY , *RADIOGRAPHY , *GAIT disorders - Abstract
CASE DESCRIPTION A 6.8-year-old neutered male Labrador Retriever-Poodle mix was evaluated because of continued left pelvic limb lameness unresponsive to conservative management I year after undergoing tibial plateau leveling osteotomy (TPLO). CLINICAL FINDINGS A jerking lateral movement of the left stifle joint was detected during walking. Orthopedic examination revealed a pivot-shift phenomenon (PSP). Palpation elicited no signs of discomfort over the TPLO plate or caudomedial aspect of the stifle joint. Radiography revealed complete bone fusion at the osteotomy site and only mild joint effusion. TREATMENT AND OUTCOME Arthrotomy was performed at the medial aspect of the stifle joint, revealing no meniscal tears. The previously applied plate was removed, and an extracapsular, synthetic, ligament-like biomaterial was placed to counteract internal tibial rotation, thereby eliminating the PSP. Six weeks later, lameness had improved considerably with no evidence of PSP; 8 weeks after surgery, the dog was assessed for sudden-onset lameness in the right pelvic limb. Cranial cruciate ligament rupture was suspected, and TPLO was performed. The PSP was identified intraoperatively, so an extracapsular implant was placed. Six weeks later, the dog had only mild lameness and no evidence of PSP in either pelvic limb. In a follow-up telephone conversation I year later, the owner reported no obvious lameness or gait abnormalities. CLINICAL RELEVANCE Use of an extracapsular implant effectively eliminated the PSP following TPLO in the dog of this report and can be considered as an intra- or postoperative option for dogs with PSP that responds poorly to conservative management. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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17. What Is Your Neurologic Diagnosis?
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BORDER collie , *FORELIMB , *LAMENESS in dogs , *CARPAL joints , *HEPATOMEGALY - Abstract
The article presents a case study of a 8-year-old spayed female Border Collie who was taken to the hospital due to progressive left thoracic limb lameness. It mentions that Border Collie was diagnosed with degenerative disease of the carpal joint and was treated with NSAID. It also mentions that physical examination reveals the presence of moderate abdominal distension and mild hepatomegaly in abdominal palpation.
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- 2017
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18. What Is Your Diagnosis?
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BACTERIAL diseases in animals , *DOG diseases , *OSTEOMYELITIS , *ANOREXIA nervosa , *LAMENESS in dogs , *CO-trimoxazole , *BACTERIAL disease treatment - Abstract
The article describes the case of a 4-month-old sexually intact female mixed-breed dog with history of anorexia combined with lameness of the left forelimb and fever. Diagnostic imaging findings and interpretation include moth-eaten pattern of bone lysis in the distal metaphysis of each radius and ulna, hematogenous osteomyelitis and hypertrophic osteodystrophy. The dog was treated with levofloxacin and trimethoprim-sulfamethoxazole following the identification of Chryseobacterium.
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- 2019
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19. GaitKeeper: A System for Measuring Canine Gait.
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Ladha, Cassim, O'Sullivan, Jack, Belshaw, Zoe, and Asher, Lucy
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NEURODEGENERATION , *GAIT in animals , *DISEASE progression , *LAMENESS in dogs , *HUMAN mechanics - Abstract
It is understood gait has the potential to be used as a window into neurodegenerative disorders, identify markers of subclinical pathology, inform diagnostic algorithms of disease progression and measure the efficacy of interventions. Dogs' gaits are frequently assessed in a veterinary setting to detect signs of lameness. Despite this, a reliable, affordable and objective method to assess lameness in dogs is lacking. Most described canine lameness assessments are subjective, unvalidated and at high risk of bias. This means reliable, early detection of canine gait abnormalities is challenging, which may have detrimental implications for dogs' welfare. In this paper, we draw from approaches and technologies used in human movement science and describe a system for objectively measuring temporal gait characteristics in dogs (step-time, swing-time, stance-time). Asymmetries and variabilities in these characteristics are of known clinical significance when assessing lameness but presently may only be assessed on coarse scales or under highly instrumented environments. The system consists an inertial measurement unit, containing a 3-axis accelerometer and gyroscope coupled with a standardized walking course. The measurement unit is attached to each leg of the dog under assessment before it is walked around the course. The data by the measurement unit is then processed to identify steps and subsequently, micro-gait characteristics. This method has been tested on a cohort of 19 healthy dogs of various breeds ranging in height from 34.2 cm to 84.9 cm. We report the system as capable of making precise step delineations with detections of initial and final contact times of foot-to-floor to a mean precision of 0.011 s and 0.048 s, respectively. Results are based on analysis of 12,678 foot falls and we report a sensitivity, positive predictive value and F-score of 0.81, 0.83 and 0.82 respectively. To investigate the effect of gait on system performance, the approach was tested in both walking and trotting with no significant performance deviation with 7249 steps reported for a walking gait and 4977 for a trotting gait. The number of steps reported for each leg were approximately equal and this consistency was true in both walking and trotting gaits. In the walking gait 1965, 1790, 1726 and 1768 steps were reported for the front left, front right, hind left and hind right legs respectively. 1361, 1250, 1176 and 1190 steps were reported for each of the four legs in the trotting gait. The proposed system is a pragmatic and precise solution for obtaining objective measurements of canine gait. With further development, it promises potential for a wide range of applications in both research and clinical practice. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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20. Static Posturography: A New Perspective in the Assessment of Lameness in a Canine Model.
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Manera, Maria E., Carrillo, José M., Batista, Miguel, Rubio, Monica, Sopena, Joaquin, Santana, Angelo, and Vilar, José M.
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LAMENESS in dogs , *OSTEOARTHRITIS in dogs , *GROWTH factors , *ELBOW diseases , *CONTROL groups - Abstract
The aim of this study was to assess the static posturography in dogs as a useful tool for diagnosis of lameness by means of the use of a pressure platform. For this purpose, a series of different parameters (pressure distribution, area of support, mean pressure, maximum pressure and statokinesiograms) were obtained from five lame dogs with unilateral elbow osteoarthritis treated with plasma rich in growth factors. Data were obtained before and 3 months after treatment, and results were compared with a control group of sound dogs of similar conformation. Significant differences were found in the above mentioned parameters between sound and lame limbs. Improvement after 3 months of treatment was also detected, demonstrating that this multi-parametric technique is an effective and reliable method for the assessment of lameness in dogs. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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21. Normal patellofemoral kinematic patterns during daily activities in dogs.
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Moore, Erica J., Kim, Stanley E., Banks, Scott A., Pozzi, Antonio, Coggeshall, Jason D., and Jones, Stephen C.
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PATELLOFEMORAL joint physiology , *MAMMAL kinematics , *LAMENESS in dogs , *PAIN in animals , *BIOMECHANICS - Abstract
Background: Patellar abnormalities are a common cause of pain and lameness in dogs; however, in vivo the relative motion between the femur and patella in dogs is not well described. The objective of this study was to define normal in vivo sagittal plane patellofemoral kinematics in three axes of motion using non-invasive methods. We hypothesized patellofemoral alignment in the sagittal plane would tightly correlate with the femorotibial flexion angle. Six healthy dogs without orthopedic disease underwent computed tomography (CT) of their hind limbs to create 3-D models of the patella and femur. Normal stifle joint motion was captured via flat-panel imaging while each dog performed a series of routine activities, including sitting, walking, and trotting. The 3-D models of the patella and femur were digitally superimposed over the radiographic images with shape-matching software and the precise movement of the patella relative to the femur was calculated. Results: As the femorotibial joint flexed, the patellofemoral joint also flexed and the patella moved caudally and distally within the femoral trochlea during each activity. Patellar flexion and distal translation during walk and sit were linearly coupled with the femorotibial flexion angle. Offset was evident while trotting, where patella poses were significantly different between early and late swing phase (p = 0.003). Patellar flexion ranged from 51 to 6° while trotting. The largest flexion angle (92°) occurred during sit. The patella traversed the entire proximodistal length of the femoral trochlea during these daily activities. Conclusions: Using single-plane flat-panel imaging, we demonstrated normal in vivo patellofemoral kinematics is tightly coupled with femorotibial kinematics; however, trot kinematic patterns did not follow the path defined by walking and stand-to-sit motions. Our normal data can be used in future studies to help define patellofemoral joint kinematics in dogs with stifle abnormalities. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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22. Effects of denervation of the hip joint on results of clinical observations and instrumented gait analysis in dogs with sodium urate crystal-induced synovitis.
- Author
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Hassan, Elham A., Lambrechts, Nicolaas E., Hsin-Yi Weng, Snyder, Paul W., and Breur, Gert J.
- Subjects
- *
CANINE hip dysplasia , *GAIT in animals , *HIP surgery , *SYNOVITIS , *LAMENESS in dogs , *DENERVATION , *THERAPEUTICS - Abstract
OBJECTIVE: To evaluate the effects of selective hip joint denervation on gait abnormalities and signs of hip joint pain in dogs. ANIMALS: 6 healthy adult hound-type dogs. PROCEDURES: Minimally invasive denervation was performed on the right hip joint of each dog. Two weeks later, sodium urate was injected into the right hip joint to induce synovitis. Dogs were evaluated clinically and by use of instrumented gait analysis before and 2 weeks after minimally invasive denervation and 4,8,and 24 hours after induction of synovitis. Dogs were euthanized, and necropsy and histologic examination were performed. RESULTS: No kinetic or kinematic gait modifications were detected 2 weeks after minimally invasive denervation. Denervation did not eliminate signs of pain and lameness associated with sodium urate-induced synovitis. Results of histologic examination confirmed that denervation was an effective method for transecting the innervation of the craniolateral and caudolateral aspects of the hip joint capsule. CONCLUSIONS AND CLINICAL RELEVANCE: In this study, minimally invasive denervation did not result in gait modifications in dogs. Denervation did not abolish the signs of pain and lameness associated with generalized induced synovitis of the hip joint. Further studies are required before conclusions can be drawn regarding the clinical usefulness of hip joint denervation for dogs with hip dysplasia. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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23. Effects of administration of adipose-derived stromal vascular fraction and platelet-rich plasma to dogs with osteoarthritis of the hip joints.
- Author
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Upchurch, David A., Renberg, Walter C., Roush, James K., Milliken, George A., and Weiss, Mark L.
- Subjects
- *
OSTEOARTHRITIS , *LAMENESS in dogs , *ARTIFICIAL hip joints , *CONTROL groups , *GONIOMETRY (Anatomy) - Abstract
OBJECTIVE To evaluate effects of simultaneous intra-articular and IV injection of autologous adipose-derived stromal vascular fraction (SVF) and platelet-rich plasma (PRP) to dogs with osteoarthritis of the hip joints. ANIMALS 22 client-owned dogs (12 placebo-treated [control] dogs and 10 treated dogs). PROCEDURES Dogs with osteoarthritis of the hip joints that caused signs of lameness or discomfort were characterized on the basis of results of orthopedic examination, goniometry, lameness score, the Canine Brief Pain Inventory (CBPI), a visual analogue scale, and results obtained by use of a pressuresensing walkway at week 0 (baseline). Dogs received a simultaneous intraarticular and IV injection of SVF and PRP or a placebo. Dogs were examined again 4, 8, 12, and 24 weeks after injection. RESULTS CBPI scores were significantly lower for the treatment group at week 24, compared with scores for the control group. Mean visual analogue scale score for the treatment group was significantly higher at week 0 than at weeks 4, 8, or 24. Dogs with baseline peak vertical force (PVF) in the lowest 25th percentile were compared, and the treatment group had a significantly higher PVF than did the control group. After the SVF-PRP injection, fewer dogs in the treated group than in the control group had lameness confirmed during examination. CONCLUSIONS A ND CLINICAL RELEVANCE For dogs with osteoarthritis of the hip joints treated with SVF and PRP, improvements in CBPI and PVF were evident at some time points, compared with results for the control group. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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24. Outcomes and complications following surgical correction of grade IV medial patellar luxation in dogs: 24 cases (2008-2014).
- Author
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Dunlap, Anna E., Kim, Stanley E., Lewis, Daniel D., Christopher, Scott A., and Pozzi, Antonio
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- *
DOG surgery , *PATELLA , *PAIN in animals , *LAMENESS in dogs , *SURGERY ,VETERINARY surgery complications - Abstract
OBJECTIVE To determine short- and long-term outcomes and complications of dogs undergoing surgical correction of grade IV medial patellar luxation (MPL). DESIGN Retrospective case series. ANIMALS 24 dogs (29 stifle joints) that underwent surgical correction of grade IV MPL between March 2008 and April 2014. PROCEDURES Medical records of all dogs were reviewed. When available, long-term follow-up information was obtained for each dog via the orthopedic surgeon (results of orthopedic examination and radiographic interpretation) and the dog's owner (responses to a questionnaire regarding postsurgical outcomes).Types of postsurgical complications and intervals to follow-up data collection were recorded. Recurrence of MPL was recorded separately. Successful outcome was defined as one without catastrophic complication, with owner-reported full or acceptable return to function and a surgeon- and owner-assigned pain or lameness score < 3. RESULTS 24% (7/29) of stifle joints had major complications, and 21% (6) of joints required surgical revision. Grade II to IV recurrence of MPL was identified in 21% (6) of stifle joints. One dog had a catastrophic complication requiring limb amputation. For all other dogs, owner-reported return to function was full or acceptable. Surgeon-assigned pain and lameness scores for all dogs at the final follow-up evaluation were < 2/5 (0 = pain or lameness free). Surgical correction of grade IV MPL had an overall success rate of 93% (27/29). CONCLUSIONS AND CLINICAL RELEVANCE Surgical correction of grade IV MPL in dogs had a favorable overall success rate; however, owners should be counseled regarding the high rate of complications associated with surgery. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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25. Chronic desmitis and enthesiophytosis of the radio-ulnar interosseous ligament in a dog.
- Author
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Deffontaines, Jean-Baptiste, Lussier, Bertrand, Bolliger, Christian, Bédard, Agathe, Doré, Monique, and Blevins, William E.
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LAMENESS in dogs ,GOLDEN retriever ,LIGAMENT diseases ,ULNA ,DOG surgery ,DISEASES - Abstract
Copyright of Canadian Veterinary Journal / Revue Vétérinaire Canadienne is the property of Canadian Veterinary Medical Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2016
26. Effectiveness of combined acupuncture and manual therapy relative to no treatment for canine musculoskeletal pain.
- Author
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Lane, David M. and Hill, Sarah A.
- Subjects
LAMENESS in dogs ,ACUPUNCTURE ,MUSCULOSKELETAL system abnormalities ,CANIDAE ,PAIN management ,VETERINARY therapeutics ,DISEASES - Abstract
Despite the rise in popularity of both acupuncture and manual therapy in veterinary medicine, and the increasing number of Canadian veterinarians practising these techniques, there is little research demonstrating their effectiveness. In this repeated measures, therapeutic trial, 47 client-owned dogs with naturally occurring lameness were assessed for clinical response to treatment. Owners were blinded to the treatment schedule and completed questionnaires to assess their dogs' comfort and mobility. Comparison between pre- and post-treatment results demonstrated that combined acupuncture and manual therapy provides immediate short-term improvement in comfort and mobility, as demonstrated by owner observed changes in play behavior (P = 0.015), walking (P < 0.001), trotting (P = 0.002), jumping (P < 0.001), descending stairs (P = 0.003), rising from a lying position (P < 0.001), and reduced stiffness after rest (P < 0.001) or following exercise (P < 0.001). Mood and attitude also improved, but did not attain statistical significance. Malgré la croissance de la popularité de l'acupuncture et de la thérapie manuelle en médecine vétérinaire et le nombre grandissant de vétérinaires canadiens qui pratiquent ces techniques, il existe peu de recherche démontrant leur efficacité. Dans cet essai thérapeutique à mesures répétées, 47 chiens appartenant à des clients atteints de boiterie naturelle ont été évalués pour leur réponse clinique au traitement. Les propriétaires n'ont pas été informés du calendrier de traitement et ils ont rempli des questionnaires afin d'évaluer le confort et la mobilité de leurs chiens. La comparaison entre les résultats avant et après le traitement ont démontré que l'acupuncture et la thérapie manuelle combinées offraient une amélioration immédiate à court terme pour le confort et la mobilité, comme le démontrent les observations faites par les propriétaires pour le comportement de jeu (P = 0,015), la marche (P < 0,001), le galop {P = 0,002), le saut (P < 0,001), la descente d'escaliers (P = 0,003), le lever d'une position couchée (P < 0,001) et une raideur réduite après le repos (P < 0,001) ou après de l'exercice (P < 0,001). L'humeur et l'attitude se sont aussi améliorées, mais sans atteindre une importance statistique. [ABSTRACT FROM AUTHOR]
- Published
- 2016
27. Pathology in Practice.
- Subjects
- *
ABNORMALITIES in dogs , *EDEMA , *LAMENESS in dogs , *PAIN , *ULTRASONIC imaging - Abstract
The article presents a case study of a 9-year-old 27-kg (59-lb) neutered male Dalmatian evaluated with the issues of swelling in the right pelvic limb's proximal portion and lameness. Physical examination, ultrasonography and serum biochemical analyse was conducted on the dog and which revealed the signs of pain. The pain was the reason of mass of mixed echogenicity in the thigh which was treated through therapeutics.
- Published
- 2018
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28. Practitioners' Corner.
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Bedos, Leila, Dennis, Ruth, and Aertsens, Adrien
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LAMENESS in dogs ,NONSTEROIDAL anti-inflammatory agents - Published
- 2018
29. What Is Your Diagnosis?
- Subjects
- *
LAMENESS in dogs , *IMAGE quality in radiography , *DIAGNOSIS - Abstract
The article presents a quiz, requesting readers to give a diagnostic decision, to treat a male English Setter dog with acute lameness of the right forelimb. It also provides radiographic images, interpretations and findings.
- Published
- 2018
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30. Pathology in Practice.
- Subjects
- *
DOG diseases , *CANCER in dogs , *THYROID diseases , *CYTOPLASMIC granules , *LAMENESS in dogs , *THYROID cancer - Abstract
The article discusses a case study of a 13-year-old neutered, male English Pointer dog, who was evaluated for one-week history of bilateral hind limb stiffness, right forelimb lameness and signs of pain in the caudal cervical region. A nodule on left lobe of thyroid gland was seen on physical examinations and microscopic fine-needle aspirate specimen examination revealed intracytoplasmic black granules on thyroid gland It discusses thyroid carcinoma and black pigmentation of the thyroid gland.
- Published
- 2018
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31. ECG of the Month.
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- *
DIAGNOSIS of dog diseases , *LAMENESS in dogs , *ELECTROCARDIOGRAPHY , *LONG QT syndrome , *TREATMENT of fractures - Abstract
The article discusses a case study of a 4-month-old spayed female Toy Poodle, who was evaluated for sudden-onset non-weight-bearing lameness of the left forelimb. It states that the dog was diagnosed with and treated for transverse distal diaphyseal fractures of the left radius and was administered hydromorphone hydrochloride for pain management. ECG recording revealed a normal mean electrical axis and prolonged QT intervals, stating long QT syndrome (LQTS).
- Published
- 2018
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32. Development of a model to induce transient synovitis and lameness in the hip joint of dogs.
- Author
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Hassan, Elham A., Lambrechts, Nicolaas E., Moore, George E., Hsin-Yi Weng, Hock Gan Heng, and Breur, Gert J.
- Subjects
- *
LAMENESS in dogs , *HIP joint diseases , *SYNOVITIS , *URATES , *ANALGESICS , *THERAPEUTICS - Abstract
OBJECTIVE To develop a model of hip joint synovitis on the basis of intra-articular injection of a sodium urate suspension in dogs and to characterize associated gait changes. ANIMALS 6 healthy adult dogs. PROCEDURES Each dog was sedated, and synovitis was induced by injection of 1 mL of a sodium urate suspension (20 mg/mL) into the right hip joint under ultrasonographic guidance. Observational and instrumented gait analyses to determine temporospatial, kinetic, and kinematic variables were performed prior to and 4,8, and 24 hours after sedation and synovitis induction. RESULTS Injection of a sodium urate suspension into the hip joint of healthy dogs resulted in lameness of the ipsilateral pelvic limb as determined by observational and instrumented gait analyses. For all dogs, lameness was clinically detectable within 1.5 to 2 hours after injection, reached its maximum intensity at 4 hours after injection, and had subsided by 24 hours after injection. CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that injection of a sodium urate suspension into the hip joint of healthy dogs reliably induced synovitis and signs of pain and lameness in the ipsilateral pelvic limb that lasted 24 hours. This model can be used in conjunction with instrumented gait analysis to provide information on gait changes associated with hip joint disease and might be useful for evaluating the efficacy of analgesics or other interventions for the treatment of hip joint disease in dogs. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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33. What Is Your Diagnosis?
- Subjects
- *
VOMITING in animals , *ABDOMINAL pain , *LAMENESS in dogs , *MEDICAL radiography , *PHYSIOLOGIC salines , *FENTANYL , *NEPHRECTOMY , *THERAPEUTICS - Abstract
The article offers two case studies first seven-month-old sexually intact female Shih Tzu with acute vomiting and abdominal pain and second a 3.5-year-old male bernese mountain dog with weight loss, inappetence, and periodic shifting forelimb lameness (FL). In first case abdominal radiography revealed diseases as gastric dilation and treated with medicines as lactated ringer solution. In the second case physical examination revealed mild bilateral FL and receive fentanyl and nephrectomy.
- Published
- 2015
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34. Single ultrasound-guided platelet-rich plasma injection for treatment of supraspinatus tendinopathy in dogs.
- Author
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Ho, Louisa K., Baltzer, Wendy I., Nemanic, Sarah, and Stieger-Vanegas, Susanne M.
- Subjects
PLATELET-rich plasma ,TENDON diseases ,LAMENESS in dogs ,SUPRASPINATUS muscles ,DOG diseases ,VETERINARY therapeutics ,DISEASES ,THERAPEUTICS - Abstract
The article cites a study which examined the efficacy of single platelet-rich plasma injection in the treatment of supraspinatus tendinopathy in dogs. Topics discussed include improvement in lameness and function in dogs noticed by their owners, detection of improvement in heterogeneity and echogenicity in tendons, and the persistence of ultrasonographic lesions in all dogs.
- Published
- 2015
35. Osteomyelitis associated with Nocardiopsis composta in a dog.
- Author
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Salas, Elisa N., Royal, Debra, Kurz, Lance, and Loy, J. Dustin
- Subjects
LAMENESS in dogs ,OSTEOMYELITIS treatment ,BONE diseases ,CLINDAMYCIN ,VETERINARY medicine ,ANTI-infective agents ,THERAPEUTICS - Abstract
The article presents a case study of a 1-year-old neutered male miniature Australian shepherd dog presented to a primary care veterinarian with a 6-week history of right hind limb weight-bearing lameness. The radiographic examination of the dog revealed osteolytic lesion in the mid-diaphysis of the limb. Empirical antimicrobial treatment was initiated in the dog with clindamycin for five months. Nocardiopsis composta in association with osteomyelitis was observed in further examination.
- Published
- 2015
36. Total hip replacement in two dogs with unsuccessful femoral head ostectomy.
- Author
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Su-Young Heo, Jae-Won Seol, and Hae-Beom Lee
- Subjects
TOTAL hip replacement ,FEMUR head ,DOG surgery ,FOLLOW-up studies (Medicine) ,LAMENESS in dogs ,SURGERY - Abstract
An English setter (case 1) and a Tibetan mastiff (case 2) presented with intermittent weight-bearing lameness on the right hind limb when trotting. The dogs had a history of femoral head and neck ostectomy (FHNO). Orthopedic examination revealed pain and crepitus on the right hip joint. The dogs underwent total hip replacement (THR). At the 2-year (case 1) and 1-year (case 2) follow-up, both dogs had resumed normal activity without lameness. The muscle mass and range of motion were significantly improved in the affected hind limb. In conclusion, FHNO with poor functional outcomes can be successfully ameliorated with THR. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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37. What Is Your Diagnosis?
- Subjects
- *
GREAT Pyrenees , *LAMENESS in dogs , *OSTEOARTHRITIS , *SYNOVITIS , *RADIOGRAPHY , *DISEASES - Abstract
The article presents a case study of a four-year-old male Great Pyrenees suffering from pelvic limb lameness. It mentions that the dog underwent orthopedic examination and radiography wherein degenerative joint disease secondary to cranial cruciate ligament injury was identified. It also notes the changes to the distal part of its femur was induced by concurrent proliferative villonodular synovitis.
- Published
- 2017
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38. Tethered Cord Syndrome Associated with a Thickened Filum Terminale in a Dog.
- Author
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De Decker, S., Gregori, T., Kenny, P.J., Hoy, C., Erles, K., and Volk, H.A.
- Subjects
- *
SPINAL cord diseases , *LAMENESS in dogs , *PARAPARESIS , *TISSUES , *COCKER spaniels , *DISEASES , *SURGERY - Abstract
The article presents a case study of a one-year-old female Cocker Spaniel with lameness in right pelvic limb. Several examinations were performed such as neurological examination revealed paraparesis and proprioceptive deficits and differential diagnosed thickening of the filum terminale that caused tethered cord syndrome (TCS) which results in dysfunction of the lumbosacral spinal cord segments. It emphasize she recovered completely after surgical transection of the filum terminale.
- Published
- 2015
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39. Radiographic Risk Factors for Contralateral Rupture in Dogs with Unilateral Cranial Cruciate Ligament Rupture.
- Author
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Chuang, Connie, Ramaker, Megan A., Kaur, Sirjaut, Csomos, Rebecca A., Kroner, Kevin T., Bleedorn, Jason A., Schaefer, Susan L., and Muir, Peter
- Subjects
- *
CRUCIATE ligament injuries , *LAMENESS in dogs , *SOFT tissue injuries , *OSTEOARTHRITIS in dogs , *STIFLE joint , *OSTEORADIOGRAPHY - Abstract
Background: Complete cranial cruciate ligament rupture (CR) is a common cause of pelvic limb lameness in dogs. Dogs with unilateral CR often develop contralateral CR over time. Although radiographic signs of contralateral stifle joint osteoarthritis (OA) influence risk of subsequent contralateral CR, this risk has not been studied in detail. Methodology/Principal Findings: We conducted a retrospective longitudinal cohort study of client-owned dogs with unilateral CR to determine how severity of radiographic stifle synovial effusion and osteophytosis influence risk of contralateral CR over time. Detailed survival analysis was performed for a cohort of 85 dogs after case filtering of an initial sample population of 513 dogs. This population was stratified based on radiographic severity of synovial effusion (graded on a scale of 0, 1, and 2) and severity of osteophytosis (graded on a scale of 0, 1, 2, and 3) of both index and contralateral stifle joints using a reproducible scoring method. Severity of osteophytosis in the index and contralateral stifles was significantly correlated. Rupture of the contralateral cranial cruciate ligament was significantly influenced by radiographic OA in both the index and contralateral stifles at diagnosis. Odds ratio for development of contralateral CR in dogs with severe contralateral radiographic stifle effusion was 13.4 at one year after diagnosis and 11.4 at two years. Odds ratio for development of contralateral CR in dogs with severe contralateral osteophytosis was 9.9 at one year after diagnosis. These odds ratios were associated with decreased time to contralateral CR. Breed, age, body weight, gender, and tibial plateau angle did not significantly influence time to contralateral CR. Conclusion: Subsequent contralateral CR is significantly influenced by severity of radiographic stifle effusion and osteophytosis in the contralateral stifle, suggesting that synovitis and arthritic joint degeneration are significant factors in the disease mechanism underlying the arthropathy. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
40. Serum Biomarkers of Clinical and Cytologic Response in Dogs with Idiopathic Immune-Mediated Polyarthropathy.
- Author
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Foster, J.D., Sample, S., Kohler, R., Watson, K., Muir, P., and Trepanier, L.A.
- Subjects
- *
ARTHRITIS in animals , *C-reactive protein , *CYTOKINES , *INTERLEUKIN-6 , *LAMENESS in dogs , *DOG diseases - Abstract
Background Immune-mediated polyarthopathy ( IMPA) is common in dogs, and is monitored by serial arthrocenteses. Hypothesis/Objectives Plasma C-reactive protein ( CRP), interleukin-6 ( IL-6), and CXCL8 (interleukin-8) would serve as noninvasive markers of joint inflammation in IMPA. Animals Nine client-owned dogs with idiopathic IMPA; 6 healthy controls. Methods Prospective study. Plasma CRP, IL-6, and CXCL8 were measured by ELISA at baseline, 2, and 4 weeks during treatment with prednisone at 50 mg/m2/day. Arthrocenteses, the canine brief pain inventory ( CBPI), and accelerometry collars were used to assess joint inflammation, lameness, and mobility at all 3 time points. Results C-reactive protein concentrations were higher in IMPA dogs (median 91.1 μg/mL, range 76.7-195.0) compared with controls (median <6.3 μg/mL, <6.3-13.7; P = .0035), and were significantly lower at week 2 (10.6 μg/mL, <6.3-48.8) and week 4 (<6.3 μg/mL, <6.3-24.4; P < .001). C-reactive protein was correlated with median CBPI scores ( r = 0.68; P = .0004), joint cellularity ( r = 0.49, P = .011), and mobility by accelerometry ( r = −0.42, P = .048). Plasma IL-6 concentrations were also higher in IMPA dogs (median 45.9 pg/mL), compared with controls (median <15.7 pg/mL; P = .0008). IL-6 was lower in IMPA dogs by week 4 (<15.7 pg/mL; P = .0099), and was modestly correlated with CBPI scores ( r = 0.47, P = .023). CXCL8 did not differ significantly between IMPA and healthy dogs. Conclusions Plasma CRP and IL-6 might be useful surrogate markers of synovial inflammation and disease activity in dogs with IMPA. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
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41. Atherosclerosis associated with vasculopathic lesions in a golden retriever with hypercholesterolemia.
- Author
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Boynosky, Nicole A. and Stokking, Laura
- Subjects
LAMENESS in dogs ,ULCER diagnosis ,VASCULITIS ,HYPERCHOLESTEREMIA ,SEPSIS ,DISSEMINATED intravascular coagulation ,DIAGNOSIS - Abstract
The article presents a case study of a two-year-old neutered male golden retriever dog suffering from lameness secondary to ulcerations of multiple digital paw pads. Topics discussed include diagnosed with vasculitis and hypercholesterolemia, death of dog due to myocardial infarction as well as severe atherosclerosis and dermatologic lesions secondary to cholesterol embolism syndrome. It further discusses the diagnosis in sepsis and disseminated intravascular coagulation in the dog.
- Published
- 2014
42. Evaluation of application of a carpal brace as a treatment for carpal ligament instability in dogs: 14 cases (2008-2011).
- Author
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Tomlinson, Julia E. and Manfredi, Jane M.
- Subjects
- *
DOGS' injuries , *MEDICAL records , *LIGAMENT injury treatment , *ISOMETRIC exercise , *LAMENESS in dogs , *RETROSPECTIVE studies - Abstract
Objective--To determine whether carpal brace application is a viable treatment for dogs with unilateral carpal ligament instability. Design--Retrospective case series. Animals--14 client-owned athletic dogs. Procedures--Medical records were reviewed to identify dogs treated with a brace for uni-lateral carpal valgus or varus instability between August 2008 and August 2011. Treatment included passive motion and isometric strengthening exercises during brace application. Results--Of the 14 dogs, 11 were considered to have returned to normal function; 11 of 12 dogs returned to agility competition. Carpal measurements before treatment indicated the af-fected limb had significantly greater valgus measurements (median, 30°; range, 30° to 35°), significantly greater varus measurements (median, 15°; range, 15° to 25°), and significantly less flexion (median, 37.5°; range, 30° to 45°), compared with results for the contralateral carpus. Long-term monitoring revealed no differences in measurements between affected and contra-lateral limbs. Valgus measurements of the affected carpus at brace removal (median, 15°; range, 15° to 20°) and at the end of long-term monitoring (median, 15°; range, 15° to 20°) were signifi-cantly lower than measurements before treatment (median, 30°; range, 30° to 35°). Dogs had significantly lower lameness scores (assessed on a scale of 0 to 5) at brace removal (median, 0; range, 0) and at the end of monitoring (median, 0; range, 0 to 2), compared with scores before treatment (median, 3; range, 1 to 3). Conclusions and Clinical Relevance--Application of a carpal brace resulted in improved stability and resolution or reduction in lameness in dogs with carpal ligament instability. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
43. A randomized controlled trial of the efficacy of autologous platelet therapy for the treatment of osteoarthritis in dogs.
- Author
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Fahie, Maria A., Ortolano, Girolamo A., Guercio, Vincent, Schaffer, Jeffrey A., Johnston, Gary, Au, Jennifer, Hettlich, Bianca A., Phillips, Tom, Allen, Matthew J., and Bertone, Alicia L.
- Subjects
- *
OSTEOARTHRITIS in dogs , *DOG diseases , *OSTEOARTHRITIS treatment , *INTRA-articular injections , *BLOOD platelets , *LAMENESS in dogs - Abstract
Objective--To determine efficacy of a single intra-articular injection of an autologous platelet concentrate for treatment of osteoarthritis in dogs. Design--Randomized, controlled, 2-center clinical trial. Animals--20 client-owned dogs with osteoarthritis involving a single joint. Procedures--Dogs were randomly assigned to a treatment or control group. In all dogs, severity of lameness and pain was scored by owners with the Hudson visual analog scale and the University of Pennsylvania Canine Brief Pain Inventory, respectively, and peak vertical force (PVF) was determined with a force platform. Dogs in the treatment group were then sedated, and a blood sample (55 mL) was obtained. Platelets were recovered by means of a point-of-use filter and injected intra-articularly within 30 minutes. Control dogs were sedated and given an intra-articular injection of saline (0.9% NaCI) solution. Assessments were repeated 12 weeks after injection of platelets or saline solution. Results--Dogs weighed between 18.3 and 63.9 kg (40.3 and 140.6 lb) and ranged from 1.5 to 8 years old. For control dogs, lameness scores, pain scores, and PVF at week 12 were not significantly different from pretreatment values. In contrast, for dogs that received platelet injections, lameness scores (55% decrease in median score), pain scores (53% decrease in median score), and PVF (12% increase in mean PVF) were significantly improved after 12 weeks, compared with pretreatment values. Conclusions and Clinical Relevance--Results suggested that a single intra-articular injection of autologous platelets resulted in significant improvements at 12 weeks in dogs with osteoarthritis involving a single joint. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
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44. Comminuted fracture of the ulnar carpal bone in a Labrador retriever dog.
- Author
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Vedrine, Bertrand
- Subjects
LABRADOR retriever ,COMMINUTED fractures ,LAMENESS in dogs ,FORELIMB ,WOUNDS & injuries ,THERAPEUTICS - Abstract
The article presents a case study of a 4-year-old male Labrador retriever dog that was brought for evaluation of right forelimb lameness. The dog had a comminuted fracture of the ulnar carpal bone and was under acute pain. It informs that radiographs of the carpus revealed the necessity of removal of bone fragments.
- Published
- 2013
45. Treatment of Hip Dysplasia in a Dog after a Failed Triple Pelvic Osteotomy with a Zurich Cementless Total Hip Replacement.
- Author
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SY Heo and H. B. Lee
- Subjects
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CANINE hip dysplasia , *PELVIC bones , *OSTEOTOMY , *TOTAL hip replacement , *ALASKAN Malamute , *LAMENESS in dogs , *VETERINARY surgery , *SURGERY - Abstract
An Alaskan Malamute (2-year-old, castrated male, 41kg) was referred with bilateral hind limb lameness. The dog had a history of a bilateral triple pelvic osteotomy (TPO) to correct hip dysplasia one year previously, a surgery that was unsuccessful. On physical examination, pain and crepitus were noted in both hip joints. There was hip joint subluxation and mild degenerative changes bilaterally seen by radiograph. A Zurich cementless total hip replacement (ZCTHR) was planned for the right hind limb. After a craniolateral approach, an acetabular cup and a cementless femoral stem were implanted. The femoral head was placed in the femoral stem, and the prosthetic joint was then reduced. At a 9 month postoperative checkup, there was no pain on palpation or manipulation of the right pelvic limb, and the range of motion was within normal limits. On radiological examination, there was no implant loosening. The ZCTHR can thus be applied in a failed TPO patient as a revision surgery. [ABSTRACT FROM AUTHOR]
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- 2013
46. Long-Term Valuation of Oral Mavacoxib in Osteoarthrosic Dogs Using Force Platform Analysis.
- Author
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Vilar, J. M., Morales, M., Santana, A., Batista, M., Miró, F., and Spinella, G.
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OSTEOARTHRITIS in dogs , *VETERINARY drugs , *ENZYME inhibitors , *VETERINARY therapeutics , *DOG diseases , *LAMENESS in dogs ,DOG anatomy - Abstract
The aim of this study was to assess the efficacy of mavacoxib, a cox-2 inhibitor, to improve the peak vertical force (PVF) and vertical impulse (VI) of lame clientowned dogs with severe coxofemoral osteoarthrosis (OA) by using a force platform. A group of ten canarian presa dogs with lameness and pain for a severe osteoarthrosis due to hip dysplasia were used for this study. Five additional sound dogs of the same breed were used as control groups. A single force platform used to register vertical forces was mounted in a 7 m runway. Mean (± SD) values for speed of dogs were 1.6±0.5 m/s. Data corresponding with 5 valid trials were recorded at walk at day 0, 7, 60 and 180 after starting treatment procedure. The dosing regimen consisted of a loading oral dose of 2 mg/kg to be repeated after 14 days, thereafter the dosing interval was 1 month. OA dogs showed a significant improvement of PVF after two months of about 7% bm in the force exerted by diseased limbs and a significant VI improvement after two months of about 1.6% bm in the VI exerted by diseased limbs. This study clearly showed that dogs treated with mavacoxib increased PVF over time, as soon as seven days after medical therapy, demonstrating a high potential for clinical use in the treatment of lameness associated with OA of hip joint. [ABSTRACT FROM AUTHOR]
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- 2013
47. Clinical assessment following tibial tuberosity advancement in 28 stifles at 6 months and 1 year after surgery.
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MacDonald, Tamara L., Allen, David A., and Monteith, Gabrielle J.
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ABNORMALITIES in dogs ,LAMENESS in dogs ,RANGE of motion of joints ,CRUCIATE ligament injuries ,SURGERY ,VETERINARY therapeutics - Abstract
The article presents a prospective study that analyzes the effect of tibial tuberosity advancement (TTA) on lameness, range of motion (ROM), and thigh circumference as well as radiographic osteoarthritis. The study is undertaken among dogs with cranial cruciate ligament (CrCL) deficiency wherein complications associated with TTA were also assessed. The results show that TTA treatment cause significant improvement in dogs that undergone surgery after a year.
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- 2013
48. In vitro synthesis of tensioned synoviocyte bioscaffolds for meniscal fibrocartilage tissue engineering.
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Warnock, Jennifer J., Baker, Lindsay, Ballard, George A., and Ott, Jesse
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DOG diseases , *MENISCUS injuries , *TISSUE engineering , *LAMENESS in dogs , *EXTRACELLULAR matrix - Abstract
Background Meniscal injury is a common cause of lameness in the dog. Tissue engineered bioscaffolds may be a treatment option for meniscal incompetency, and ideally would possess meniscuslike extracellular matrix (ECM) and withstand meniscal tensile hoop strains. Synovium may be a useful cell source for meniscal tissue engineering because of its natural role in meniscal deficiency and its in vitro chondrogenic potential. The objective of this study is to compare meniscal -like extracellular matrix content of hyperconfluent synoviocyte cell sheets ("HCS") and hyperconfluent synoviocyte sheets which have been tensioned over wire hoops (tensioned synoviocyte bioscaffolds, "TSB") and cultured for 1 month. Results Long term culture with tension resulted in higher GAG concentration, higher chondrogenic index, higher collagen concentration, and type II collagen immunoreactivity in TSB versus HCS. Both HCS and TSB were immunoreactive for type I collagen, however, HCS had mild, patchy intracellular immunoreactivity while TSB had diffuse moderate immunoreactivity over the entire bisocaffold. The tissue architecture was markedly different between TSB and HCS, with TSB containing collagen organized in bands and sheets. Both HCS and TSB expressed alpha smooth muscle actin and displayed active contractile behavior. Double stranded DNA content was not different between TSB and HCS, while cell viability decreased in TSB. Conclusions Long term culture of synoviocytes with tension improved meniscal- like extra cellular matrix components, specifically, the total collagen content, including type I and II collagen, and increased GAG content relative to HCS. Future research is warranted to investigate the potential of TSB for meniscal tissue engineering. [ABSTRACT FROM AUTHOR]
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- 2013
- Full Text
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49. Load redistribution in walking and trotting Beagles with induced forelimb lameness.
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Abdelhadi, Jalal, Wefstaedt, Patrick, Galindo-Zamora, Vladimir, Anders, Alexandra, Nolte, Ingo, and Schilling, Nadja
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LAMENESS in dogs , *FORELIMB , *BEAGLE (Dog breed) , *DOG diseases , *WALKING , *GAIT in animals , *ANIMAL locomotion , *DISEASES - Abstract
Objective--To evaluate the load redistribution mechanisms in walking and trotting dogs with induced forelimb lameness. Animals--7 healthy adult Beagles. Procedures--Dogs walked and trotted on an instrumented treadmill to determine control values for peak and mean vertical force as well as verticle impulse for all 4 limbs. A small sphere was attached to the ventral pad of the right forelimb paw to induce a reversible lameness, and recordings were repeated for both gaits. Additionally, footfall patterns were assessed to test for changes in temporal gait variables. Results--During walking and trotting, peak and mean vertical force as well as vertical impulse were decreased in the ipsilateral forelimb, increased in the contralateral hind limb, and remained unchanged in the ipsilateral hind limb after lameness was induced. All 3 variables were increased in the contralateral forelimb during trotting, whereas only mean vertical force and vertical impulse were increased during walking. Stance phase duration increased in the contralateral forelimb and hind limb during walking but not during trotting. Conclusions and Clinical Relevance--Analysis of the results suggested that compensatory load redistribution mechanisms in dogs depend on the gait. All 4 limbs should be evaluated in basic research and clinical studies to determine the effects of lameness on the entire body. Further studies are necessary to elucidate specific mechanisms for unloading of the affected limb and to determine the long-term effects of load changes in animals with chronic lameness. [ABSTRACT FROM AUTHOR]
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- 2013
- Full Text
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50. Comparison of Force Plate Gait Analysis and Owner Assessment of Pain Using the Canine Brief Pain Inventory in Dogs with Osteoarthritis.
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Brown, D.C., Boston, R.C., and Farrar, J.T.
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OSTEOARTHRITIS in dogs , *COMPARATIVE studies , *HEALTH outcome assessment , *CHRONIC pain , *PLACEBOS , *CARPROFEN , *BLIND experiment , *LAMENESS in dogs - Abstract
Background Lameness assessment using force plate gait analysis ( FPGA) and owner assessment of chronic pain using the Canine Brief Pain Inventory ( CBPI) are valid and reliable methods of evaluating canine osteoarthritis. There are no studies comparing these 2 outcome measures. Objective Evaluate the relationship between CBPI pain severity ( PS) and interference ( PI) scores with the vertical forces of FPGA as efficacy measures in canine osteoarthritis. Animals Sixty-eight client-owned dogs with osteoarthritis (50 hind limb and 18 forelimb). Methods Double-blind, randomized. Owners completed the CBPI, and dogs underwent FPGA on days 0 and 14. Dogs received carprofen or placebo on days 1 through 14. The change in PS and PI scores from day 0 to 14 were compared to the change in peak vertical force ( PVF) and vertical impulse ( VI). Results PS and PI scores significantly decreased in carprofen- compared with placebo-treated dogs ( P = .002 and P = .03, respectively). PVF and VI significantly increased in carprofen- compared with placebo-treated dogs ( P = .006 and P = .02, respectively). There was no correlation or concordance between the PS or PI score changes and change in PVF or VI. Conclusions and Clinical Importance In these dogs with hind limb or forelimb osteoarthritis, owner assessment of chronic pain using the CBPI and assessment of lameness using FPGA detected significant improvement in dogs treated with carprofen. The lack of correlation or concordance between the change in owner scores and vertical forces suggests that owners were focused on behaviors other than lameness when making efficacy evaluations in their dogs. [ABSTRACT FROM AUTHOR]
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- 2013
- Full Text
- View/download PDF
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