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3. Clinical presentation, disease course, and outcome of COVID-19 in hospitalized patients with and without pre-existing cardiac disease: a cohort study across 18 countries

Author

Linschoten, M., Uijl, A., Schut, A., Jakob, C. E. M., Romao, L. R., Bell, R. M., McFarlane, E., Stecher, M., Zondag, A. G. M., van Iperen, E. P. A., Hermans-van Ast, J. F., Lea, N. C., Schaap, J., Jewbali, L. S., Smits, P. C., Patel, R. S., Aujayeb, A., van Smeden, M., Siebelink, H. J., Williams, S., Pilgram, L., Tieleman, R. G., Williams, B., Asselbergs, F. W., Al-Ali, A. K., Al-Muhanna, F. A., Al-Rubaish, A. M., Al-Windy, N. Y. Y., Alkhalil, M., Almubarak, Y. A., Al Nafie, A. N., Al Shahrani, M., Al Shehri, A. M., Anning, C., Anthonio, R. L., Badings, E. A., Ball, C., Van Beek, E. A., Ten Berg, J. M., Von Bergwelt-Baildon, M., Bianco, M., Blagova, O., V, Bleijendaal, H., Bor, W. L., Borgmann, S., van Boxem, A. J. M., van den Brink, F. S., Bucciarelli-Ducci, C., Van Bussel, B. C. T., Byrom-Goulthorp, R., Captur, G., Caputo, M., Charlotte, N., vom Dahl, J., Dark, P., De Sutter, J., Degenhardt, C., Delsing, C. E., Dolff, S., Dorman, H. G. R., Drost, J. T., Eberwein, L., Emans, M. E., Er, A. G., Ferreira, J. B., Forner, M. J., Friedrichs, A., Gabriel, L., Groenemeijer, B. E., Groenendijk, A. L., Gruener, B., Guggemos, W., Haerkens-Arends, H. E., Hanses, F., Hedayat, B., Heigener, D., van der Heijden, D. J., Hellou, E., Hellwig, K., Henkens, M. T. H. M., Hermanides, R. S., Hermans, W. R. M., van Hessen, M. W. J., Heymans, S. R. B., Hilt, A. D., van der Horst, I. C. C., Hower, M., van Ierssel, S. H., Isberner, N., Jensen, B., Kearney, M. T., Kielstein, J. T., Kietselaer, B. L. J. H., Kochanek, M., Kolk, M. Z. H., Koning, A. M. H., Kopylov, P. Y., Kuijper, A. F. M., Kwakkel-van, E. R. P. J. M., Lanznaster, J., van der Linden, M. M. J. M., van der Lingen, A. C. J., Linssen, G. C. M., Lomas, D., Maarse, M., Magdelijns, F. J. H., Magro, M., Markart, P., Martens, F. M. A. C., Mazzilli, S. G., McCann, G. P., van der Meer, P., Meijs, M. F. L., Merle, U., Messiaen, P., Milovanovic, M., Monraats, P. S., Montagna, L., Moriarty, A., Moss, A. J., Mosterd, A., Nadalin, S., Nattermann, J., Neufang, M., Nierop, P. R., Offerhaus, J. A., Van Ofwegen-Hanekamp, C. E. E., Parker, E., Persoon, A. M., Piepel, C., Pinto, Y. M., Poorhosseini, H., Prasad, S., Raafs, A. G., Raichle, C., Rauschning, D., Redon, J., Reidinga, A. C., Ribeiro, M. I. A., Riedel, C., Rieg, S., Ripley, D. P., Rommele, C., Rothfuss, K., Ruddel, J., Ruthrich, M. M., Salah, R., Saneei, E., Saxena, M., Schellings, D. A. A. M., Scholte, N. T. B., Schubert, J., Seelig, J., Shafiee, A., Shore, A. C., Spinner, C., Stieglitz, S., Strauss, R., Sturkenboom, N. H., Tessitore, E., Thomson, R. J., Timmermans, P. J. R., Tio, R. A., Tjong, F. V. Y., Tometten, L., Trauth, J., Van Craenenbroeck, E. M., van Veen, H. P. A. A., den Uil, C. A., Vehreschild, M. J. G. T., Veldhuis, L., I, Veneman, T., Verschure, D. O., Voigt, I, Walter, L., vande Watering, D. J., de Vries, J. K., vande Wal, R. M. A., Westendorp, I. C. D., Westendorp, P. H. M., Westhoff, T., Weytjens, C., Wierda, E., Wille, K., de With, K., Worm, M., Woudstra, P., Wu, K. W., Zaal, R., Zaman, A. G., van der Zee, P. M., Zijlstra, L. E., Alling, T. E., Ahmed, R., Bayraktar-Verver, E. C. E., van Aken, K., Jimenes, Bermudez F. J., Biole, C. A., Den Boer-Penning, P., Bontje, M., Bos, M., Bosch, L., Broekman, M., Broeyer, F. J. F., de Bruijn, E. A. W., Bruinsma, S., Cardoso, N. M., Cosyns, B., Len, van Da D. H., Dekimpe, E., Domange, J., van Doorn, J. L., van DOorn, P., Dormal, F., Drost, I. M. J., Dunnink, A., van Eck, J. W. M., Elshinawy, K., Gevers, R. M. M., Gognieva, D. G., van der Graaf, M., Grangeon, S., Guclu, A., Habib, A., Haenen, N. A., Hamilton, K., Handgraaf, S., Heidbuchel, H., Hendriks-van Woerden, M., Hessels-Linnemeijer, B. M., Hosseini, K., Huisman, J., Jacobs, T. C., Jansen, S. E., Janssen, A., Jourdan, K., ten Kate, G. L., van Kempen, M. J., Kievit, C. M., Kleikers, P., Knufman, N., van der Kooi, S. E., Koole, B. A. S., Koole, M. A. C., Kui, K. K., Kuipers-Elferink, L., Lemoine, I, Lensink, E., van Marrewijk, V, Meijer, E. J., Melein, A. J., Mesitskaya, D. F., van Nes, C. P. M., Paris, F. M. A., Perrelli, M. G., Pieterse-Rots, A., Pisters, R., Polkerman, B. C., van Poppel, A., Reinders, S., Reitsma, M. J., Ruiter, A. H., Selder, J. L., van der Sluis, A., Sousa, A. I. C., Tajdini, M., Sanchez, Tercedor L., Van de Heyning, C. M., Vial, H., Vlieghe, E., Vonkeman, H. E., Vreugdenhil, P., de Vries, T. A. C., Willems, A. M., Wils, A. M., Zoet-Nugteren, S. K., Linschoten, M., Uijl, A., Schut, A., Jakob, C. E. M., Romao, L. R., Bell, R. M., McFarlane, E., Stecher, M., Zondag, A. G. M., van Iperen, E. P. A., Hermans-van Ast, J. F., Lea, N. C., Schaap, J., Jewbali, L. S., Smits, P. C., Patel, R. S., Aujayeb, A., van Smeden, M., Siebelink, H. J., Williams, S., Pilgram, L., Tieleman, R. G., Williams, B., Asselbergs, F. W., Al-Ali, A. K., Al-Muhanna, F. A., Al-Rubaish, A. M., Al-Windy, N. Y. Y., Alkhalil, M., Almubarak, Y. A., Al Nafie, A. N., Al Shahrani, M., Al Shehri, A. M., Anning, C., Anthonio, R. L., Badings, E. A., Ball, C., Van Beek, E. A., Ten Berg, J. M., Von Bergwelt-Baildon, M., Bianco, M., Blagova, O., V, Bleijendaal, H., Bor, W. L., Borgmann, S., van Boxem, A. J. M., van den Brink, F. S., Bucciarelli-Ducci, C., Van Bussel, B. C. T., Byrom-Goulthorp, R., Captur, G., Caputo, M., Charlotte, N., vom Dahl, J., Dark, P., De Sutter, J., Degenhardt, C., Delsing, C. E., Dolff, S., Dorman, H. G. R., Drost, J. T., Eberwein, L., Emans, M. E., Er, A. G., Ferreira, J. B., Forner, M. J., Friedrichs, A., Gabriel, L., Groenemeijer, B. E., Groenendijk, A. L., Gruener, B., Guggemos, W., Haerkens-Arends, H. E., Hanses, F., Hedayat, B., Heigener, D., van der Heijden, D. J., Hellou, E., Hellwig, K., Henkens, M. T. H. M., Hermanides, R. S., Hermans, W. R. M., van Hessen, M. W. J., Heymans, S. R. B., Hilt, A. D., van der Horst, I. C. C., Hower, M., van Ierssel, S. H., Isberner, N., Jensen, B., Kearney, M. T., Kielstein, J. T., Kietselaer, B. L. J. H., Kochanek, M., Kolk, M. Z. H., Koning, A. M. H., Kopylov, P. Y., Kuijper, A. F. M., Kwakkel-van, E. R. P. J. M., Lanznaster, J., van der Linden, M. M. J. M., van der Lingen, A. C. J., Linssen, G. C. M., Lomas, D., Maarse, M., Magdelijns, F. J. H., Magro, M., Markart, P., Martens, F. M. A. C., Mazzilli, S. G., McCann, G. P., van der Meer, P., Meijs, M. F. L., Merle, U., Messiaen, P., Milovanovic, M., Monraats, P. S., Montagna, L., Moriarty, A., Moss, A. J., Mosterd, A., Nadalin, S., Nattermann, J., Neufang, M., Nierop, P. R., Offerhaus, J. A., Van Ofwegen-Hanekamp, C. E. E., Parker, E., Persoon, A. M., Piepel, C., Pinto, Y. M., Poorhosseini, H., Prasad, S., Raafs, A. G., Raichle, C., Rauschning, D., Redon, J., Reidinga, A. C., Ribeiro, M. I. A., Riedel, C., Rieg, S., Ripley, D. P., Rommele, C., Rothfuss, K., Ruddel, J., Ruthrich, M. M., Salah, R., Saneei, E., Saxena, M., Schellings, D. A. A. M., Scholte, N. T. B., Schubert, J., Seelig, J., Shafiee, A., Shore, A. C., Spinner, C., Stieglitz, S., Strauss, R., Sturkenboom, N. H., Tessitore, E., Thomson, R. J., Timmermans, P. J. R., Tio, R. A., Tjong, F. V. Y., Tometten, L., Trauth, J., Van Craenenbroeck, E. M., van Veen, H. P. A. A., den Uil, C. A., Vehreschild, M. J. G. T., Veldhuis, L., I, Veneman, T., Verschure, D. O., Voigt, I, Walter, L., vande Watering, D. J., de Vries, J. K., vande Wal, R. M. A., Westendorp, I. C. D., Westendorp, P. H. M., Westhoff, T., Weytjens, C., Wierda, E., Wille, K., de With, K., Worm, M., Woudstra, P., Wu, K. W., Zaal, R., Zaman, A. G., van der Zee, P. M., Zijlstra, L. E., Alling, T. E., Ahmed, R., Bayraktar-Verver, E. C. E., van Aken, K., Jimenes, Bermudez F. J., Biole, C. A., Den Boer-Penning, P., Bontje, M., Bos, M., Bosch, L., Broekman, M., Broeyer, F. J. F., de Bruijn, E. A. W., Bruinsma, S., Cardoso, N. M., Cosyns, B., Len, van Da D. H., Dekimpe, E., Domange, J., van Doorn, J. L., van DOorn, P., Dormal, F., Drost, I. M. J., Dunnink, A., van Eck, J. W. M., Elshinawy, K., Gevers, R. M. M., Gognieva, D. G., van der Graaf, M., Grangeon, S., Guclu, A., Habib, A., Haenen, N. A., Hamilton, K., Handgraaf, S., Heidbuchel, H., Hendriks-van Woerden, M., Hessels-Linnemeijer, B. M., Hosseini, K., Huisman, J., Jacobs, T. C., Jansen, S. E., Janssen, A., Jourdan, K., ten Kate, G. L., van Kempen, M. J., Kievit, C. M., Kleikers, P., Knufman, N., van der Kooi, S. E., Koole, B. A. S., Koole, M. A. C., Kui, K. K., Kuipers-Elferink, L., Lemoine, I, Lensink, E., van Marrewijk, V, Meijer, E. J., Melein, A. J., Mesitskaya, D. F., van Nes, C. P. M., Paris, F. M. A., Perrelli, M. G., Pieterse-Rots, A., Pisters, R., Polkerman, B. C., van Poppel, A., Reinders, S., Reitsma, M. J., Ruiter, A. H., Selder, J. L., van der Sluis, A., Sousa, A. I. C., Tajdini, M., Sanchez, Tercedor L., Van de Heyning, C. M., Vial, H., Vlieghe, E., Vonkeman, H. E., Vreugdenhil, P., de Vries, T. A. C., Willems, A. M., Wils, A. M., and Zoet-Nugteren, S. K.

Abstract

Aims Patients with cardiac disease are considered high risk for poor outcomes following hospitalization with COVID-19. The primary aim of this study was to evaluate heterogeneity in associations between various heart disease subtypes and in-hospital mortality. Methods and results We used data from the CAPACITY-COVID registry and LEOSS study. Multivariable Poisson regression models were fitted to assess the association between different types of pre-existing heart disease and in-hospital mortality. A total of 16 511 patients with COVID-19 were included (21.1% aged 66-75 years; 40.2% female) and 31.5% had a history of heart disease. Patients with heart disease were older, predominantly male, and often had other comorbid conditions when compared with those without. Mortality was higher in patients with cardiac disease (29.7%; n= 1545 vs. 15.9%; n= 1797). However, following multivariable adjustment, this difference was not significant [adjusted risk ratio (aRR) 1.08, 95% confidence interval (CI) 1.02-1.15; P = 0.12 (corrected for multiple testing)]. Associations with in-hospital mortality by heart disease subtypes differed considerably, with the strongest association for heart failure (aRR 1.19, 95% CI 1.10-1.30; P <0.018) particularly for severe (New York Heart Association class III/IV) heart failure (aRR 1.41, 95% CI 1.20-1.64; P < 0.018). None of the other heart disease subtypes, including ischaemic heart disease, remained significant after multivariable adjustment. Serious cardiac complications were diagnosed in <1% of patients. Conclusion Considerable heterogeneity exists in the strength of association between heart disease subtypes and in-hospital mortality. Of all patients with heart disease, those with heart failure are at greatest risk of death when hospitalized with COVID-19. Serious cardiac complications are rare during hospitalization. [GRAPHICS] .

Published
2022

5. Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease

Author

Borghi, C, Agabiti-Rosei, E, Johnson, R, Kielstein, J, Lurbe, E, Mancia, G, Redon, J, Stack, A, Tsioufis, K, Borghi C., Agabiti-Rosei E., Johnson R. J., Kielstein J. T., Lurbe E., Mancia G., Redon J., Stack A. G., Tsioufis K. P., Borghi, C, Agabiti-Rosei, E, Johnson, R, Kielstein, J, Lurbe, E, Mancia, G, Redon, J, Stack, A, Tsioufis, K, Borghi C., Agabiti-Rosei E., Johnson R. J., Kielstein J. T., Lurbe E., Mancia G., Redon J., Stack A. G., and Tsioufis K. P.

Abstract

During the last century, there has been an increasing prevalence of hyperuricaemia noted in many populations. While uric acid is usually discussed in the context of gout, hyperuricaemia is also associated with hypertension, chronic kidney disease, hypertriglyceridaemia, obesity, atherosclerotic heart disease, metabolic syndrome, and type 2 diabetes. Here we review the connection between hyperuricaemia and cardiovascular, kidney and metabolic diseases. Contrary to the popular view that uric acid is an inert metabolite of purine metabolism, recent studies suggest serum uric acid may have a variety of pro-inflammatory, pro-oxidative and vasoconstrictive actions that may contribute to cardiometabolic diseases. Hyperuricaemia is a predictive factor for the development of hypertension, metabolic syndrome, type 2 diabetes, coronary artery disease, left ventricular hypertrophy, atrial fibrillation, myocardial infarction, stroke, heart failure and chronic kidney disease. Treatment with uric acid-lowering therapies has also been found to improve outcomes in patients with hypertension and kidney disease, in some but not all studies. In conclusion, uric acid is emerging as a potentially treatable risk factor for cardiometabolic diseases, and more clinical trials investigating the potential benefit of lowering serum uric acid are recommended in individuals with hyperuricaemia with and without deposition and concomitant hypertension, metabolic syndrome or chronic kidney disease.

Published
2020

6. Extracorporeal treatment for calcium channel blocker poisoning: systematic review and recommendations from the EXTRIP workgroup.

Author

Nolin T.D., MacLaren R., Megarbane B., Mowry J., Osterman M., Peng A., Roy J.-P., Vijayan A., Wood D., Yates C., Wong A., Hoffman R.S., Walsh S.J., Roberts D.M., Gosselin S., Bunchman T.E., Kebede S., Lavergne V., Ghannoum M., Alhatali B., Anseeuw K., Berling I., Bouchard J., Bird S., Chin P., Doi K., Galvao T., Goldfarb D., Hassanian H., Hoegberg L., Kallab S., Kielstein J., Li Y., Macedo E., Nolin T.D., MacLaren R., Megarbane B., Mowry J., Osterman M., Peng A., Roy J.-P., Vijayan A., Wood D., Yates C., Wong A., Hoffman R.S., Walsh S.J., Roberts D.M., Gosselin S., Bunchman T.E., Kebede S., Lavergne V., Ghannoum M., Alhatali B., Anseeuw K., Berling I., Bouchard J., Bird S., Chin P., Doi K., Galvao T., Goldfarb D., Hassanian H., Hoegberg L., Kallab S., Kielstein J., Li Y., and Macedo E.

Abstract

Background: Calcium channel blockers (CCBs) are commonly used to treat conditions such as arterial hypertension and supraventricular dysrhythmias. Poisoning from these drugs can lead to severe morbidity and mortality. We aimed to determine the utility of extracorporeal treatments (ECTRs) in the management of CCB poisoning. Method(s): We conducted systematic reviews of the literature, screened studies, extracted data, summarized findings, and formulated recommendations following published EXTRIP methods. Result(s): A total of 83 publications (6 in vitro and 1 animal experiments, 55 case reports or case series, 19 pharmacokinetic studies, 1 cohort study and 1 systematic review) met inclusion criteria regarding the effect of ECTR. Toxicokinetic or pharmacokinetic data were available on 210 patients (including 32 for amlodipine, 20 for diltiazem, and 52 for verapamil). Regardless of the ECTR used, amlodipine, bepridil, diltiazem, felodipine, isradipine, mibefradil, nifedipine, nisoldipine, and verapamil were considered not dialyzable, with variable levels of evidence, while no dialyzability grading was possible for nicardipine and nitrendipine. Data were available for clinical analysis on 78 CCB poisoned patients (including 32 patients for amlodipine, 16 for diltiazem, and 23 for verapamil). Standard care (including high dose insulin euglycemic therapy) was not systematically administered. Clinical data did not suggest an improvement in outcomes with ECTR. Consequently, the EXTRIP workgroup recommends against using ECTR in addition to standard care for patients severely poisoned with either amlodipine, diltiazem or verapamil (strong recommendations, very low quality of the evidence (1D)). There were insufficient clinical data to draft recommendation for other CCBs, although the workgroup acknowledged the low dialyzability from, and lack of biological plausibility for, ECTR. Conclusion(s): Both dialyzability and clinical data do not support a clinical benefit from ECTRs

Published
2021

9. Hyperuricaemia and gout in cardiovascular, metabolic and kidney disease

Author

Borghi C, Agabiti-Rosei E, Johnson R, Kielstein J, Lurbe E, Mancia G, Redon J, Stack A, and Tsioufis K

Subjects
nutritional and metabolic diseases, urologic and male genital diseases
Abstract

During the last century, there has been an increasing prevalence of hyperuricaemia noted in many populations. While uric acid is usually discussed in the context of gout, hyperuricaemia is also associated with hypertension, chronic kidney disease, hypertriglyceridaemia, obesity, atherosclerotic heart disease, metabolic syndrome, and type 2 diabetes. Here we review the connection between hyperuricaemia and cardiovascular, kidney and metabolic diseases. Contrary to the popular view that uric acid is an inert metabolite of purine metabolism, recent studies suggest serum uric acid may have a variety of pro-inflammatory, pro-oxidative and vasoconstrictive actions that may contribute to cardiometabolic diseases. Hyperuricaemia is a predictive factor for the development of hypertension, metabolic syndrome, type 2 diabetes, coronary artery disease, left ventricular hypertrophy, atrial fibrillation, myocardial infarction, stroke, heart failure and chronic kidney disease. Treatment with uric acid-lowering therapies has also been found to improve outcomes in patients with hypertension and kidney disease, in some but not all studies. In conclusion, uric acid is emerging as a potentially treatable risk factor for cardiometabolic diseases, and more clinical trials investigating the potential benefit of lowering serum uric acid are recommended in individuals with hyperuricaemia with and without deposition and concomitant hypertension, metabolic syndrome or chronic kidney disease. Copyright © 2020 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

Published
2020

11. Serumuric acidandthe riskof cardiovascular and renal disease

Author

Borghi, C, Rosei, E, Bardin, T, Dawson, J, Dominiczak, A, Kielstein, J, Manolis, A, Perez-Ruiz, F, Mancia, G, Rosei, EA, Kielstein, JT, Manolis, AJ, Borghi, C, Rosei, E, Bardin, T, Dawson, J, Dominiczak, A, Kielstein, J, Manolis, A, Perez-Ruiz, F, Mancia, G, Rosei, EA, Kielstein, JT, and Manolis, AJ

Abstract

Substantial evidence suggests that chronic hyperuricemia is an independent risk factor for hypertension, metabolic syndrome, chronic kidney disease (CKD) and cardiovascular diseases. This highlights the need for greater attention to serum uric acid levels when profiling patients, and suggests that the threshold above which uricemia is considered abnormal is 6 mg/dl, in light of the available evidence. Another important question is whether lowering serum uric acid can improve cardiovascular and renal outcomes, and what therapeutic mechanism of action could provide more clinical benefits to patients; the available literature shows a trend toward improvement associated with administration of urate-lowering drugs, in particular for the xanthine oxidase inhibitors. The demonstrated efficacy of urate-lowering therapy on outcomes other than gout flares leads to the consideration that treatment may be beneficial even in the absence of overt gout when hyperuricemia accompanies other clinical conditions, such as urate deposition, advanced CKD or cardiovascular risk factors.

Published
2015

12. AKI - Clinical

Author

Gok Oguz, E., primary, Olmaz, R., additional, Turgutalp, K., additional, Muslu, N., additional, Sungur, M. A., additional, Kiykim, A., additional, Van Biesen, W., additional, Vanmassenhove, J., additional, Glorieux, G., additional, Vanholder, R., additional, Chew, S., additional, Forster, K., additional, Kaufeld, T., additional, Kielstein, J., additional, Schilling, T., additional, Haverich, A., additional, Haller, H., additional, Schmidt, B., additional, Hu, P., additional, Liang, X., additional, Chen, Y., additional, LI, R., additional, Jiang, F., additional, LI, Z., additional, Shi, W., additional, Lim, C. C. W., additional, Chia, C. M. L., additional, Tan, A. K., additional, Tan, C. S., additional, Ng, R., additional, Subramani, S., additional, Perez de Jose, A., additional, Bernis Carro, C., additional, Madero Jarabo, R., additional, Bustamante, J., additional, Sanchez Tomero, J. A., additional, Chung, W., additional, Ro, H., additional, Chang, J. H., additional, Lee, H. H., additional, Jung, J. Y., additional, Fazzari, L., additional, Giuliani, A., additional, Scrivano, J., additional, Pettorini, L., additional, Benedetto, U., additional, Luciani, R., additional, Roscitano, A., additional, Napoletano, A., additional, Coclite, D., additional, Cordova, E., additional, Punzo, G., additional, Sinatra, R., additional, Mene, P., additional, Pirozzi, N., additional, Shavit, L., additional, Manilov, R., additional, Algur, N., additional, Wiener-Well, Y., additional, Slotki, I., additional, Pipili, C., additional, Vrettou, C. S., additional, Avrami, K., additional, Economidou, F., additional, Glynos, K., additional, Ioannidou, S., additional, Markaki, V., additional, Douka, E., additional, Nanas, S., additional, De Pascalis, A., additional, Cofano, P., additional, Proia, S., additional, Valletta, A., additional, Vitale, O., additional, Russo, F., additional, Buongiorno, E., additional, Filiopoulos, V., additional, Biblaki, D., additional, Lazarou, D., additional, Chrysis, D., additional, Fatourou, M., additional, Lafoyianni, S., additional, Vlassopoulos, D., additional, Zakiyanov, O., additional, Kriha, V., additional, Vachek, J., additional, Svarcova, J., additional, Zima, T., additional, Tesar, V., additional, Kalousova, M., additional, Kaushik, M., additional, Ronco, C., additional, Cruz, D., additional, Zhang, L., additional, Zhang, W., additional, Chen, N., additional, Ejaz, A. A., additional, Kambhampati, G., additional, Ejaz, N., additional, Dass, B., additional, Lapsia, V., additional, Arif, A. A., additional, Asmar, A., additional, Shimada, M., additional, Alsabbagh, M., additional, Aiyer, R., additional, Johnson, R., additional, Chen, T.-H., additional, Chang, C.-H., additional, Chang, M.-Y., additional, Tian, Y.-C., additional, Hung, C.-C., additional, Fang, J.-T., additional, Yang, C.-W., additional, Chen, Y.-C., additional, Cantaluppi, V., additional, Quercia, A. D., additional, Figliolini, F., additional, Giacalone, S., additional, Pacitti, A., additional, Gai, M., additional, Guarena, C., additional, Leonardi, G., additional, Biancone, L., additional, Camussi, G., additional, Segoloni, G. P., additional, De Cal, M., additional, Lentini, P., additional, Clementi, A., additional, Virzi, G. M., additional, Scalzotto, E., additional, Lacquaniti, A., additional, Donato, V., additional, Fazio, M. R., additional, Lucisano, S., additional, Cernaro, V., additional, Lupica, R., additional, Buemi, M., additional, Helvaci, I., additional, Anik, E., additional, Wani, M., additional, Wani, D. I., additional, Bhat, D. M. A., additional, Banday, D. K., additional, Najar, D. M. S., additional, Reshi, D. A. R., additional, Palla, D. N. A., additional, Iglesias, P., additional, Olea, T., additional, Vega-Cabrera, C., additional, Heras, M., additional, Bajo, M. A., additional, Del Peso, G., additional, Arias, M. J., additional, Selgas, R., additional, Diez, J. J., additional, Daher, E., additional, Costa, P. L., additional, Pereira, E. N. S., additional, Santos, R. D. P., additional, Abreu, K. L., additional, Silva Junior, G., additional, Pereira, E. D. B., additional, Raimundo, M., additional, Crichton, S., additional, Syed, Y., additional, Martin, J., additional, Whiteley, C., additional, Bennett, D., additional, Ostermann, M., additional, Gjyzari, A., additional, Thereska, N., additional, Koroshi, A., additional, Barbullushi, M., additional, Kodra, S., additional, Idrizi, A., additional, Strakosha, A., additional, Petrela, E., additional, Lemmich Smith, J., additional, Klimenko, A., additional, Tuykhmenev, E., additional, Villevalde, S., additional, Kobalava, Z., additional, Avdoshina, S., additional, Tyukhmenev, E., additional, Efremovtseva, M., additional, Hayashi, H., additional, Suzuki, S., additional, Kataoka, K., additional, Kondoh, Y., additional, Taniguchi, H., additional, Sugiyama, D., additional, Nishimura, K., additional, Sato, W., additional, Maruyama, S., additional, Matsuo, S., additional, Yuzawa, Y., additional, Geraldine, D., additional, Muriel, F., additional, Alexandre, H., additional, Eric, R., additional, Fu, P., additional, Pozzato, M., additional, Ferrari, F., additional, Cecere, P., additional, Mesiano, P., additional, Vallero, A., additional, Livigni, S., additional, Quarello, F., additional, Hudier, L., additional, Decaux, O., additional, Haddj-Elmrabet, A., additional, Mandart, L., additional, Lino-Daniel, M., additional, Bridoux, F., additional, Renaudineau, E., additional, Sawadogo, T., additional, Le Pogamp, P., additional, Vigneau, C., additional, Famee, D., additional, Koo, H. M., additional, Oh, H. J., additional, Han, S. H., additional, Choi, K. H., additional, Kang, S.-W., additional, Mehdi, M., additional, Nicolas, M., additional, Mariat, C., additional, Shah, P., additional, Kute, V. B., additional, Vanikar, A., additional, Gumber, M., additional, Patel, H., additional, Trivedi, H., additional, Manetos, C., additional, Poulaki, S., additional, Tripodaki, E.-S., additional, Papastylianou, A., additional, Routsi, C., additional, Uchida, K., additional, Kensuke, U., additional, Yamagata, K., additional, Saitou, C., additional, Okada, M., additional, Chita, G., additional, Davies, M., additional, Veriawa, Y., additional, Naicker, S., additional, Mukhopadhyay, P., additional, Mukherjee, D., additional, Mishra, R., additional, Kar, M., additional, Zickler, D., additional, Wesselmann, H., additional, Schindler, R., additional, Gutierrez*, E., additional, Egido, J., additional, Rubio-Navarro, A., additional, Buendia, I., additional, Blanco-Colio, L. M., additional, Toldos, O., additional, Manzarbeitia, F., additional, De Lorenzo, A., additional, Sanchez, R., additional, Praga^, M., additional, Moreno^, J. A., additional, Kim, M. Y., additional, Kang, N. R., additional, Jang, H. R., additional, Lee, J. E., additional, Huh, W., additional, Kim, Y.-G., additional, Kim, D. J., additional, Hong, S.-C., additional, Kim, J.-S., additional, Oh, H. Y., additional, Okamoto, T., additional, Kamata, K., additional, Naito, S., additional, Tazaki, H., additional, Kan, S., additional, Anne-Kathrin, L.-G., additional, Matthias, K., additional, Speer, T., additional, Andreas, L., additional, Heinrich, G., additional, Thomas, V., additional, Poppleton, A., additional, Danilo, F., additional, Lai, C.-F., additional, Wu, V.-C., additional, Shiao, C.-C., additional, Huang, T.-M., additional, Wu, K.-D., additional, Bedford, M., additional, Farmer, C., additional, Irving, J., additional, Stevens, P., additional, Patera, F., additional, Mattozzi, F., additional, Battistoni, S., additional, Fagugli, R. M., additional, Park, M. Y., additional, Choi, S. J., additional, Kim, J. G., additional, Hwang, S. D., additional, Xie, H., additional, Chen, H., additional, Xu, S., additional, He, Q., additional, Liu, J., additional, Hu, W., additional, Liu, Z., additional, Dalboni, M., additional, Blaya, R., additional, Quinto, B. M., additional, Narciso, R., additional, Oliveira, M., additional, Monte, J., additional, Durao, M., additional, Cendoroglo, M., additional, Batista, M., additional, Hanemann, A. L., additional, Liborio, A., additional, Martins, A., additional, Pinheiro, M. C. C., additional, Meneses, G., additional, De Paula Pessoa, R., additional, Sousa, M., additional, Bezerra, F. S. M., additional, Albuquerque, P. L. M. M., additional, Lima, J. B., additional, Lima, C. B., additional, Veras, M. D. S. B., additional, Nemoto Matsui, T., additional, Totoli, C., additional, Cruz Andreoli, M. C., additional, Vilela Coelho, M. P., additional, Guimaraes de Souza, N. K., additional, Ammirati, A. L., additional, De Carvalho Barreto, F., additional, Ferraz Neto, B.-H., additional, Fortunato Cardoso Dos Santos, B., additional, Abraham, A., additional, Abraham, G., additional, Mathew, M., additional, Duarte, P. M. A., additional, Duarte, F. B., additional, Barros, E. M., additional, Castro, F. Q. S., additional, Palomba, H., additional, Castro, I., additional, Sousa, S. R., additional, Jesus, A. N., additional, Romano, T., additional, Burdmann, E., additional, Yu, L., additional, Kwon, S. H., additional, You, J. Y., additional, Hyun, Y. K., additional, Woo, S. A., additional, Jeon, J. S., additional, Noh, H. J., additional, Han, D. C., additional, Tozija, L., additional, Petronievic, Z., additional, Selim, G., additional, Nikolov, I., additional, Stojceva-Taneva, O., additional, Cakalaroski, K., additional, Lukasz, A., additional, Beneke, J., additional, Menne, J., additional, Schiffer, M., additional, Polanco, N., additional, Hernandez, E., additional, Gutierrez, E., additional, Gutierrez Millet, V., additional, Gonzalez Monte, E., additional, Morales, E., additional, Praga, M., additional, Francisco Javier, L., additional, Nuria, G.-F., additional, Jose Maria, M.-G., additional, Bes Rastrollo, M., additional, Angioi, A., additional, Conti, M., additional, Cao, R., additional, Atzeni, A., additional, Pili, G., additional, Matta, V., additional, Murgia, E., additional, Melis, P., additional, Binda, V., additional, Pani, A., additional, Thome*, F., additional, Leusin, F., additional, Barros, E., additional, Morsch, C., additional, Balbinotto, A., additional, Pilla, C., additional, Premru, V., additional, Buturovic-Ponikvar, J., additional, Ponikvar, R., additional, Marn-Pernat, A., additional, Knap, B., additional, Kovac, J., additional, Gubensek, J., additional, Kersnic, B., additional, Krnjak, L., additional, Prezelj, M., additional, Granatova, J., additional, Havrda, M., additional, Hruskova, Z., additional, Kratka, K., additional, Remes, O., additional, Mokrejsova, M., additional, Bolkova, M., additional, Lanska, V., additional, Rychlik, I., additional, Uniacke, M. D., additional, Lewis, R. J., additional, Harris, S., additional, Roderick, P., additional, Martin, N., additional, Ulrich, K., additional, Jan, B., additional, Jorn, B., additional, Reinhard, B., additional, Jan, K., additional, Hermann, H., additional, Meyer Tobias, F., additional, Leyla, R., additional, Schmidt Bernhard, M. W., additional, Harald, S., additional, Jurgen, S., additional, Tanja, K., additional, Mario, S., additional, Sang Hi, E., additional, Claus, M., additional, Frank, V., additional, Aleksej, S., additional, Sengul, S., additional, Robert, S., additional, Karin, W., additional, Feikah, G., additional, Menne Tobias, F., additional, Meyer Tobias, N., additional, Beutel, G., additional, Fleig, S., additional, Steinhoff, J., additional, Meyer, T., additional, Hafer, C., additional, Bramstedt, J., additional, Busch, V., additional, Vischedyk, M., additional, Kuhlmann, U., additional, Ries, W., additional, Mitzner, S., additional, Mees, S., additional, Stracke, S., additional, Nurnberger, J., additional, Gerke, P., additional, Wiesner, M., additional, Sucke, B., additional, Abu-Tair, M., additional, Kribben, A., additional, Klause, N., additional, Merkel, F., additional, Schnatter, S., additional, Dorresteijn, E., additional, Samuelsson, O., additional, Brunkhorst, R., additional, Stec-Hus Registry, G., additional, Reising, A., additional, Bange, F.-C., additional, Hiss, M., additional, Vetter, F., additional, Bode-Boger, S. M., additional, Martens-Lobenhoffer, J., additional, Schmidt, B. M. W., additional, Kielstein, J. T., additional, Shin, H. S., additional, Jung, Y. S., additional, and Rim, H., additional

Published
2012
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16. TISSUE INJURY AND REPAIR

Author

Wang, X. H., primary, Hu, L., additional, Klein, J. D., additional, Minakuchi, H., additional, Wakino, S., additional, Hosoya, K., additional, Yoshifuji, A., additional, Hayashi, K., additional, Itoh, H., additional, Tanaka, T., additional, Higashijima, Y., additional, Tanaka, S., additional, Yamaguchi, J., additional, Nangaku, M., additional, Martino, F., additional, Kielstein, J., additional, Bang, C., additional, Thum, T., additional, Lorenzen, J., additional, Stokman, G., additional, El-Hachioui, M., additional, Florquin, S., additional, Pap, D., additional, Himer, L., additional, Szebeni, B., additional, Sziksz, E., additional, Riedl, Z., additional, Iwakura, Y., additional, Nagy Szakal, D., additional, Kis, E., additional, Onody, A., additional, Veres-Szekely, A., additional, Javorszky, E., additional, Koszegi, S., additional, Fekete, A., additional, A. Brandt, F., additional, Reusz, G., additional, Tulassay, T., additional, and Vannay, A., additional

Published
2014
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17. CKD LAB METHODS, PROGRESSION & RISK FACTORS 1

Author

Heisterkamp, M., primary, Titze, S., additional, Lorenzen, J., additional, Eckardt, K.-U., additional, Koettgen, A., additional, Kielstein, J. T., additional, Bouquegneau, A., additional, Vidal-Petiot, E., additional, Vrtovsnik, F., additional, Cavalier, E., additional, Krzesinski, J. M., additional, Flamant, M., additional, Delanaye, P., additional, Anguiano, L., additional, Riera, M., additional, Pascual, J., additional, Barrios, C., additional, Betriu, A., additional, Valdivielso, J. M., additional, Fernandez, E., additional, Soler, M. J., additional, Denys, M.-A., additional, Viaene, A., additional, Goessaert, A.-S., additional, Delanghe, J., additional, Everaert, K., additional, Kim, Y. S., additional, Choi, M. J., additional, Deok, J. Y., additional, Kim, S. G., additional, Bevc, S., additional, Hojs, N., additional, Hojs, R., additional, Ekart, R., additional, Gorenjak, M., additional, Puklavec, L., additional, Piskunowicz, M., additional, Hofmann, L., additional, Zurcher, E., additional, Bassi, I., additional, Zweiacker, C., additional, Stuber, M., additional, Narkiewicz, K., additional, Vogt, B., additional, Burnier, M., additional, Pruijm, M., additional, Rusu, E., additional, Zilisteanu, D., additional, Atasie, T., additional, Circiumaru, A., additional, Carstea, F., additional, Ecobici, M., additional, Rosca, M., additional, Tanase, C., additional, Mihai, S., additional, Voiculescu, M., additional, Jeon, Y. D., additional, Polenakovic, M., additional, Pop-Jordanova, N., additional, Hung, S.-C., additional, Tarng, D.-C., additional, Tuta, L., additional, Stanigut, A., additional, Mesiano, P., additional, Rollino, C., additional, Ferro, M., additional, Beltrame, G., additional, Massara, C., additional, Quattrocchio, G., additional, Borca, M., additional, Bazzan, M., additional, Roccatello, D., additional, Maksudova, A., additional, Urasaeva, L. I., additional, Khalfina, T. N., additional, Tekce, H., additional, Kin Tekce, B., additional, Aktas, G., additional, Alcelik, A., additional, Sengul, E., additional, Lindic, J., additional, Purg, D., additional, Skamen, J., additional, Krsnik, M., additional, Skoberne, A., additional, Pajek, J., additional, Kveder, R., additional, Bren, A., additional, Kovac, D., additional, Delgado, G., additional, Drechsler, C., additional, Wanner, C., additional, Blouin, K., additional, Pilz, S., additional, Tomaschitz, A., additional, Kleber, M. E., additional, Willmes, C., additional, Krane, V., additional, Marz, W., additional, Ritz, E., additional, Van Gilst, W. H., additional, Van Der Harst, P., additional, De Boer, R. A., additional, Scholze, A., additional, Petersen, L., additional, Hocher, B., additional, Rasmussen, L. M., additional, Tepel, M., additional, De Paula, E. A., additional, Vanelli, C. P., additional, Caminhas, M. S., additional, Soares, B. C., additional, Bassoli, F. A., additional, Da Costa, D. M. N., additional, Lanna, C. M. M., additional, Galil, A. G. S., additional, Colugnati, F. A. B., additional, Costa, M. B., additional, Bastos, M. G., additional, De Paula, R. B., additional, Santoro, D., additional, Zappulla, Z., additional, Alibrandi, A., additional, Tomasello Andulajevic, M., additional, Licari, M., additional, Baldari, S., additional, Buemi, M., additional, Cernaro, V., additional, Campenni, A., additional, Pallet, N., additional, Chauvet, S., additional, Levi, C., additional, Meas-Yedid, V., additional, Beaune, P., additional, Thevet, E., additional, Karras, A., additional, Santos, S., additional, Malheiro, J., additional, Campos, A., additional, Pedroso, S., additional, Santos, J., additional, Cabrita, A., additional, Mayor, M. M., additional, Ayala, R., additional, Ramos, C., additional, Franco, S., additional, Guillen, R., additional, Kim, J. S., additional, Yang, J. W., additional, Han, B. G., additional, Choi, S. O., additional, Tudor, M.-N., additional, Navajas Martinez, M. F., additional, Vaduva, C., additional, Maria, D. T., additional, Mota, E., additional, Clari, R., additional, Mongilardi, E., additional, Vigotti, F. N., additional, Consiglio, V., additional, Scognamiglio, S., additional, Nazha, M., additional, Roggero, S., additional, Piga, A., additional, Piccoli, G., additional, Mukhopadhyay, P., additional, Patar, K., additional, Chaterjee, N., additional, and Ganguly, K., additional

Published
2014
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22. Peritoneal dialysis II

Author

Yayar, O., primary, Buyukbakkal, M., additional, Eser, B., additional, Yildirim, T., additional, Ercan, Z., additional, Erdogan, B., additional, Kali, A., additional, Merhametsiz, O., additional, Haspulat, A., additional, Akdag, I., additional, Ayli, M. D., additional, Quach, T., additional, Tregaskis, P., additional, Menahem, S., additional, Koukounaras, J., additional, Mott, N., additional, Walker, R., additional, Zeiler, M., additional, Santarelli, S., additional, Degano, G., additional, Monteburini, T., additional, Agostinelli, R. M., additional, Marinelli, R., additional, Ceraudo, E., additional, Grzelak, T., additional, Kramkowska, M., additional, Walczak, M., additional, Czyzewska, K., additional, Guney, I., additional, Turkmen, K., additional, Yazici, R., additional, Arslan, S., additional, Altintepe, L., additional, Yeksan, M., additional, Vaduva, C., additional, Popa, S., additional, Mota, M., additional, Mota, E., additional, Wan Md Adnan, W. A. H., additional, Zaharan, N. L., additional, Moreiras-Plaza, M., additional, Blanco-Garcia, R., additional, Beato-Coo, L., additional, Cossio-Aranibar, C., additional, Martin-Baez, I., additional, Santos, M. T., additional, Fonseca, I., additional, Santos, O., additional, Aguiar, P., additional, Rocha, M. J., additional, Carvalho, M. J., additional, Cabrita, A., additional, Rodrigues, A., additional, Guo, Z., additional, Lai, X., additional, Theodoridis, M., additional, Panagoutsos, S., additional, Thodis, E., additional, Karanikas, M., additional, Mitrakas, A., additional, Kriki, P., additional, Kantartzi, K., additional, Passadakis, P., additional, Vargemezis, V., additional, Vakilzadeh, N., additional, Pruijm, M., additional, Burnier, M., additional, Halabi, G., additional, Azevedo, P., additional, Carvalho, M., additional, Laplante, S., additional, Rutherford, P., additional, Shutov, E., additional, Isachkina, A., additional, Gorelova, E., additional, Troya, M.-I., additional, Teixido, J., additional, Pedreira, G., additional, Del Rio, M., additional, Romero, R., additional, Bonet, J., additional, Zhang, X., additional, Ma, J., additional, Kim, Y., additional, Kim, J.-K., additional, Song, Y. R., additional, Kim, S. G., additional, Kim, H. J., additional, Eloot, S., additional, Vanholder, R., additional, Van Biesen, W., additional, Heaf, J., additional, Pedersen, C., additional, Elgborn, A., additional, Arabaci, T., additional, Emrem, G., additional, Keles, M., additional, Kizildag, A., additional, Martino, F., additional, Amici, G., additional, Rodighiero, M. P., additional, Crepaldi, C., additional, Ronco, C., additional, Tanaka, H., additional, Tsuneyoshi, S., additional, Yamasaki, K., additional, Daijo, Y., additional, Tatsumoto, N., additional, Al-Hilali, N., additional, Hussain, N., additional, Fathy, V., additional, Negm, H., additional, Alhilali, M., additional, Grzegorzewska, A., additional, Cieszynski, K., additional, Kaczmarek, A., additional, Sowinska, A., additional, Soleymanian, T., additional, Najafi, I., additional, Ganji, M. R., additional, Ahmadi, F., additional, Saddadi, F., additional, Hakemi, M., additional, Amini, M., additional, Tong, L. N. M. N., additional, Yongcheng, H. N. M. N., additional, Qijun, W. N. M. N., additional, Shaodong, L. N. M. N., additional, Velioglu, A., additional, Albaz, M., additional, Arikan, H., additional, Tuglular, S., additional, Ozener, C., additional, Bakirdogen, S., additional, Eren, N., additional, Mehtap, O., additional, Bek, S. G., additional, Cekmen, M. B., additional, Yilmaz, A., additional, Cabana Carcasi, M. L. L., additional, Fernandez Ferreiro, A., additional, Fidalgo Diaz, M., additional, Becerra Mosquera, V., additional, Alonso Valente, R., additional, Buttigieg, J., additional, Borg Cauchi, A., additional, Rogers, M., additional, Buhagiar, L., additional, Farrugia Agius, J., additional, Vella, M. P., additional, Farrugia, E., additional, Han, J. H., additional, Kim, H. R., additional, Ko, K. I., additional, Kim, C. H., additional, Koo, H. M., additional, Doh, F. M., additional, Lee, M. J., additional, Oh, H. J., additional, Han, S. H., additional, Yoo, T.-H., additional, Kang, S.-W., additional, Choi, K. H., additional, Sikorska, D., additional, Frankiewicz, D., additional, Klysz, P., additional, Schwermer, K., additional, Hoppe, K., additional, Nealis, J., additional, Kaczmarek, J., additional, Baum, E., additional, Wanic-Kossowska, M., additional, Pawlaczyk, K., additional, Oko, A., additional, Hiss, M., additional, Gerstein, F., additional, Haller, H., additional, Gueler, F., additional, Fukasawa, M., additional, Manabe, T., additional, Wan, Q., additional, He, Y., additional, Zhu, D., additional, Li, J., additional, Xu, H., additional, Yayar, O., additional, Oztemel, A., additional, Pilcevic, D., additional, Kovacevic, Z., additional, Maksic, D., additional, Paunic, Z., additional, Tadic-Pilcevic, J., additional, Mijuskovic, M., additional, Petrovic, M., additional, Obrencevic, K., additional, Rabrenovic, V., additional, Ignjatovic, L., additional, Terzic, B., additional, Jovanovic, D., additional, Chang, C.-H., additional, Chang, Y.-S., additional, Busuioc, M., additional, Guerraoui, A., additional, Caillette-Beaudoin, A., additional, Bahte, S. K., additional, Kielstein, J. T., additional, Polinder-Bos, H., additional, Emmelot-Vonk, M., additional, and Gaillard, C., additional

Published
2013
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23. Circulating dendritic cell precursors in chronic kidney disease: a cross-sectional study

Author

Paul, Katharina, Kretzschmar, Daniel, Yilmaz, Atilla, Bärthlein, Barbara, Titze, Stephanie, Wolf, Gunter, Busch, Martin, GCKD-Study Investigators, Eitner, Frank, Schlieper, Georg Rainer, Findeisen, K., Arweiler, E., Ernst, S., Unger, M., Flöge, Jürgen, Schaeffner, E., Baid-Agrawal, S., Petzold, K., Schindler, R., Hilgers, K. F., Hübner, S., Avendano, S., Becker-Grosspietsch, D., Köttgen, A., Schultheiss, U., Meder, S., Mitsch, E., Walz, G., Lorenzen, J., Kielstein, J. T., Otto, P., Haller, H., Sommerer, C., Föllinger, C., Löschner, T., Zeier, M., Busch, M., Paul, K., Dittrich, L., Wolf, G., Sitter, T., Hilge, R., Blank, C., Krane, V., Schmiedeke, D., Toncar, S., Cavitt, D., Wanner, C., Franz, S., Eckardt, K. U., Titze, S., Hauck, N., Seuchter, S. A., Hausknecht, B., Rittmeier, M., Weigel, A., Prokosch, H. U., Bärthlein, B., Haberländer, K., Beck, A., Ganslandt, T., Stefan, S., Knispel, S., Dressel, T., Gefeller, O., Schmid, M., Malzer, M., Reis, A., Ekici, A. B., Kronenberg, F., Kollerits, B., Weißensteiner, H., Forer, L., Schönherr, S., Oefner, P., and Gronwald, W.

Subjects
Nephrology, Male, Myeloid, 610 Medizin, Disease, Comorbidity, Coronary Artery Disease, Gastroenterology, Coronary artery disease, Medizinische Fakultät, Risk Factors, Germany, Dendritic Cells/pathology, Prevalence, 570 Biowissenschaften, Biologie, Hematopoietic Stem Cells/pathology, Aged, 80 and over, ddc:610, Middle Aged, Coronary Artery Disease/pathology, Renal Insufficiency, Chronic/pathology, Causality, medicine.anatomical_structure, Female, ddc:570, medicine.symptom, Research Article, Adult, medicine.medical_specialty, ddc:500, Germany/epidemiology, Inflammation, Young Adult, Immune system, Internal medicine, medicine, Humans, Renal Insufficiency, Chronic, Aged, business.industry, Dendritic Cells, medicine.disease, Hematopoietic Stem Cells, Blood Cell Count, Blood Cell Count/statistics & numerical data, Cross-Sectional Studies, Immunology, 500 Naturwissenschaften, business, Kidney disease
Abstract

BACKGROUND: Dendritic cells (DC) are professional antigen-presenting cells in the immune system. They patrol the blood as circulating dendritic cell precursors (DCP). Decreased blood DCP count has been shown to be related to atherosclerotic plaque burden. Since chronic kidney disease (CKD) is associated with chronic inflammation and increased cardiovascular risk, the aim of our study was to investigate a potential effect of CKD on circulating DCP numbers especially in patients with a history of cardiovascular disease. METHODS: The number of circulating myeloid (mDCP), plasmacytoid (pDCP), and total DCP (tDCP) was analysed by flow cytometry in 245 patients with CKD stage 3 (with and without known cardiovascular events) and 85 coronary healthy controls. In addition, data were compared with a historical group of 130 patients with known coronary artery disease (CAD). RESULTS: Compared to controls, patients with CKD 3 revealed a significant decrease in circulating mDCP (-29%), pDCP (-43%), and tDCP (-38%) (P < 0.001, respectively). Compared with CAD-patients, the decrease in circulating DCP in CKD was comparable or even more pronounced indicating a potential role for DCP in cardiovascular risk potentiation due to CKD. CONCLUSIONS: Based on previous findings in CAD, the marked decrease of DCP in CKD implicates a potential role for DCP as a mediator of cardiovascular disease. Whether DCP in CKD may act as new cardiovascular biomarkers needs to be established in future prospective trials., authors on behalf of the GCKD-Study Investigators

Published
2013
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28. Experimental pathology

Author

Yi Chun, D. X., primary, Alexandre, H., additional, Edith, B., additional, Nacera, O., additional, Julie, P., additional, Chantal, J., additional, Eric, R., additional, Zhang, X., additional, Jin, Y., additional, Miravete, M., additional, Dissard, R., additional, Klein, J., additional, Gonzalez, J., additional, Caubet, C., additional, Pecher, C., additional, Pipy, B., additional, Bascands, J.-L., additional, Mercier-Bonin, M., additional, Schanstra, J., additional, Buffin-Meyer, B., additional, Claire, R., additional, Rigothier, C., additional, Richard, D., additional, Sebastien, L., additional, Moin, S., additional, Chantal, B., additional, Christian, C., additional, Jean, R., additional, Migliori, M., additional, Cantaluppi, V., additional, Mannari, C., additional, Medica, D., additional, Giovannini, L., additional, Panichi, V., additional, Goldwich, A., additional, Alexander, S., additional, Andre, G., additional, Amann, K., additional, Migliorini, A., additional, Sagrinati, C., additional, Angelotti, M. L., additional, Mulay, S. R., additional, Ronconi, E., additional, Peired, A., additional, Romagnani, P., additional, Anders, H.-J., additional, Chiang, W. C., additional, Lai, C. F., additional, Peng, W.-H., additional, Wu, C. F., additional, Chang, F.-C., additional, Chen, Y.-T., additional, Lin, S.-L., additional, Chen, Y. M., additional, Wu, K. D., additional, Lu, K.-S., additional, Tsai, T. J., additional, Virgine, O., additional, Qing Feng, F., additional, Zhang, S.-Y., additional, Dominique, D., additional, Vincent, A., additional, Marina, C., additional, Philippe, L., additional, Georges, G., additional, Pawlak, A., additional, Sahali, D., additional, Matsumoto, S., additional, Kiyomoto, H., additional, Ichimura, A., additional, Dan, T., additional, Nakamichi, T., additional, Tsujita, T., additional, Akahori, K., additional, Ito, S., additional, Miyata, T., additional, Xie, S., additional, Zhang, B., additional, Shi, W., additional, Yang, Y., additional, Nagasu, H., additional, Satoh, M., additional, Kidokoro, K., additional, Nishi, Y., additional, Ihoriya, C., additional, Kadoya, H., additional, Sasaki, T., additional, Kashihara, N., additional, Wu, C.-F., additional, Chou, Y.-H., additional, Duffield, J., additional, Rocca, C., additional, Gregorini, M., additional, Corradetti, V., additional, Valsania, T., additional, Bedino, G., additional, Bosio, F., additional, Pattonieri, E. F., additional, Esposito, P., additional, Sepe, V., additional, Libetta, C., additional, Rampino, T., additional, Dal Canton, A., additional, Omori, H., additional, Kawada, N., additional, Inoue, K., additional, Ueda, Y., additional, Yamamoto, R., additional, Matsui, I., additional, Kaimori, J., additional, Takabatake, Y., additional, Moriyama, T., additional, Isaka, Y., additional, Rakugi, H., additional, Wasilewska, A., additional, Taranta-Janusz, K., additional, Deebek, W., additional, Kuroczycka-Saniutycz, E., additional, Lee, A. S., additional, Lee, J. E., additional, Jung, Y. J., additional, Kang, K. P., additional, Lee, S., additional, Kim, W., additional, Arfian, N., additional, Emoto, N., additional, Yagi, K., additional, Nakayama, K., additional, Hartopo, A. B., additional, Nugrahaningsih, D. A., additional, Yanagisawa, M., additional, Hirata, K.-I., additional, Munoz-Felix, J. M., additional, Lopez-Novoa, J. M., additional, Martinez-Salgado, C., additional, Oujo, B., additional, Arevalo, M., additional, Bernabeu, C., additional, Perez-Barriocanal, F., additional, Jesper, K., additional, Nathalie, V., additional, Pierre, G., additional, Yi Chun, D. X., additional, Iyoda, M., additional, Shibata, T., additional, Matsumoto, K., additional, Shindo-Hirai, Y., additional, Kuno, Y., additional, Wada, Y., additional, Akizawa, T., additional, Schwartz, I., additional, Schwartz, D., additional, Prot Bertoye, C., additional, Terryn, S., additional, Claver, J., additional, Beghdadi, W. B., additional, Monteiro, R., additional, Blank, U., additional, Devuyst, O., additional, Daugas, E., additional, Van Beneden, K., additional, Geers, C., additional, Pauwels, M., additional, Mannaerts, I., additional, Van den Branden, C., additional, Van Grunsven, L. A., additional, Seckin, I., additional, Pekpak, M., additional, Uzunalan, M., additional, Uruluer, B., additional, Kokturk, S., additional, Ozturk, Z., additional, Sonmez, H., additional, Yaprak, E., additional, Furuno, Y., additional, Tsutsui, M., additional, Morishita, T., additional, Shimokawa, H., additional, Otsuji, Y., additional, Yanagihara, N., additional, Kabashima, N., additional, Ryota, S., additional, Kanegae, K., additional, Miyamoto, T., additional, Nakamata, J., additional, Ishimatsu, N., additional, Tamura, M., additional, Nakagawa, T., additional, Ichikawa, K., additional, Miyamoto, M., additional, Takabayashi, D., additional, Yamazaki, H., additional, Kakeshita, K., additional, Koike, T., additional, Kagitani, S., additional, Tomoda, F., additional, Hamashima, T., additional, Ishii, Y., additional, Inoue, H., additional, Sasahara, M., additional, El Machhour, F., additional, Kerroch, M., additional, Mesnard, L., additional, Chatziantoniou, C., additional, Dussaule, J.-C., additional, Inui, K., additional, Sasai, F., additional, Maruta, Y., additional, Nishiwaki, H., additional, Kawashima, E., additional, Inoue, Y., additional, Yoshimura, A., additional, Musacchio, E., additional, Priante, G., additional, Valvason, C., additional, Sartori, L., additional, Baggio, B., additional, Kim, J. H., additional, Gross, O., additional, Diana, R., additional, Gry, D. H., additional, Asimal, B., additional, Johanna, T., additional, Imke, S.-E., additional, Lydia, W., additional, Gerhard-Anton, M., additional, Hassan, D., additional, Cano, J. L., additional, Griera, M., additional, Olmos, G., additional, Martin, P., additional, Cortes, M. A., additional, Lopez-Ongil, S., additional, Rodriguez-Puyol, D., additional, DE Frutos, S., additional, Gonzalez, M., additional, Luengo, A., additional, Rodriguez-Puyol, M., additional, Calleros, L., additional, Lupica, R., additional, Lacquaniti, A., additional, Donato, V., additional, Maggio, R., additional, Mastroeni, C., additional, Lucisano, S., additional, Cernaro, V., additional, Fazio, M. R., additional, Quartarone, A., additional, Buemi, M., additional, Kacik, M., additional, Goedicke, S., additional, Eggert, H., additional, Hoyer, J. D., additional, Wurm, S., additional, Steege, A., additional, Banas, M., additional, Kurtz, A., additional, Banas, B., additional, Lasagni, L., additional, Lazzeri, E., additional, Romoli, S., additional, Schaefer, I., additional, Teng, B., additional, Worthmann, K., additional, Haller, H., additional, Schiffer, M., additional, Prattichizzo, C., additional, Netti, G. S., additional, Rocchetti, M. T., additional, Cormio, L., additional, Carrieri, G., additional, Stallone, G., additional, Grandaliano, G., additional, Ranieri, E., additional, Gesualdo, L., additional, Kucher, A., additional, Smirnov, A., additional, Parastayeva, M., additional, Beresneva, O., additional, Kayukov, I., additional, Zubina, I., additional, Ivanova, G., additional, Abed, A., additional, Schlekenbach, L., additional, Foglia, B., additional, Kwak, B., additional, Chadjichristos, C., additional, Queisser, N., additional, Schupp, N., additional, Brand, S., additional, Himer, L., additional, Szebeni, B., additional, Sziksz, E., additional, Saijo, S., additional, Kis, E., additional, Prokai, A., additional, Banki, N. F., additional, Fekete, A., additional, Tulassay, T., additional, Vannay, A., additional, Hegner, B., additional, Schaub, T., additional, Lange, C., additional, Dragun, D., additional, Klinkhammer, B. M., additional, Rafael, K., additional, Monika, M., additional, Anna, M., additional, Van Roeyen, C., additional, Boor, P., additional, Eva Bettina, B., additional, Simon, O., additional, Esther, S., additional, Floege, J., additional, Kunter, U., additional, Janke, D., additional, Jankowski, J., additional, Hayashi, M., additional, Takamatsu, I., additional, Horimai, C., additional, Yoshida, T., additional, Seno DI Marco, G., additional, Koenig, M., additional, Stock, C., additional, Reiermann, S., additional, Amler, S., additional, Koehler, G., additional, Fobker, M., additional, Buck, F., additional, Pavenstaedt, H., additional, Lang, D., additional, Brand, M., additional, Plotnikov, E., additional, Morosanova, M., additional, Pevzner, I., additional, Zorova, L., additional, Pulkova, N., additional, Zorov, D., additional, Wornle, M., additional, Ribeiro, A., additional, Belling, F., additional, Merkle, M., additional, Nakazawa, D., additional, Nishio, S., additional, Shibasaki, S., additional, Tomaru, U., additional, Akihiro, I., additional, Kobayashi, I., additional, Imanishi, Y., additional, Kurajoh, M., additional, Nagata, Y., additional, Yamagata, M., additional, Emoto, M., additional, Michigami, T., additional, Ishimura, E., additional, Inaba, M., additional, Wu, C.-C., additional, Lu, K.-C., additional, Chen, J.-S., additional, Chu, P., additional, Lin, Y.-F., additional, Eller, K., additional, Schroll, A., additional, Kirsch, A., additional, Huber, J., additional, Weiss, G., additional, Theurl, I., additional, Rosenkranz, A. R., additional, Zawada, A., additional, Rogacev, K., additional, Achenbach, M., additional, Fliser, D., additional, Held, G., additional, Heine, G. H., additional, Miyamoto, Y., additional, Iwao, Y., additional, Watanabe, H., additional, Kadowaki, D., additional, Ishima, Y., additional, Chuang, V. T. G., additional, Sato, K., additional, Otagiri, M., additional, Maruyama, T., additional, Iwatani, H., additional, Honda, D., additional, Noguchi, T., additional, Tanaka, M., additional, Tanaka, H., additional, Fukagawa, M., additional, Pircher, J., additional, Koppel, S., additional, Mannell, H., additional, Krotz, F., additional, Virzi, G. M., additional, Bolin, C., additional, Cruz, D., additional, Scalzotto, E., additional, De Cal, M., additional, Vescovo, G., additional, Ronco, C., additional, Grobmayr, R., additional, Lech, M., additional, Ryu, M., additional, Aoshima, Y., additional, Mizobuchi, M., additional, Ogata, H., additional, Kumata, C., additional, Nakazawa, A., additional, Kondo, F., additional, Ono, N., additional, Koiwa, F., additional, Kinugasa, E., additional, Freisinger, W., additional, Lale, N., additional, Lampert, A., additional, Ditting, T., additional, Heinlein, S., additional, Schmieder, R. E., additional, Veelken, R., additional, Nave, H., additional, Perthel, R., additional, Suntharalingam, M., additional, Bode-Boger, S., additional, Beutel, G., additional, Kielstein, J., additional, Rodrigues-Diez, R., additional, Rayego-Mateos, S., additional, Lavoz, C., additional, Stark Aroeira, L. G., additional, Orejudo, M., additional, Alique, M., additional, Ortiz, A., additional, Egido, J., additional, Ruiz-Ortega, M., additional, Oskar, W., additional, Rusan, C., additional, Padberg, J.-S., additional, Wiesinger, A., additional, Reuter, S., additional, Grabner, A., additional, Kentrup, D., additional, Lukasz, A., additional, Oberleithner, H., additional, Pavenstadt, H., additional, Kumpers, P., additional, Eberhardt, H. U., additional, Skerka, C., additional, Chen, Q., additional, Hallstroem, T., additional, Hartmann, A., additional, Kemper, M. J., additional, Zipfel, P. F., additional, N'gome-Sendeyo, K., additional, Fan, Q.-F., additional, Toblli, J., additional, Cao, G., additional, Giani, J. F., additional, Dominici, F. P., additional, Kim, J. S., additional, Yang, J. W., additional, Kim, M. K., additional, Han, B. G., additional, and Choi, S. O., additional

Published
2012
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29. Extracorporeal dialysis: techniques and adequacy

Author

Donadio, C., primary, Kanaki, A., additional, Martin-Gomez, A., additional, Garcia, S., additional, Palacios-Gomez, M., additional, Donadio, C., additional, Calia, D., additional, Colombini, E., additional, DI Francesco, F., additional, Ghimenti, S., additional, Onor, M., additional, Tognotti, D., additional, Fuoco, R., additional, Marka-Castro, E., additional, Torres Zamora, M. I., additional, Giron-Mino, J., additional, Jaime-Solis, M. A., additional, Arteaga, L. M., additional, Romero, H., additional, Akonur, A., additional, Leypoldt, K., additional, Asola, M., additional, Culleton, B., additional, Eloot, S., additional, Glorieux, G., additional, Nathalie, N., additional, Vanholder, R., additional, Perez de Jose, A., additional, Verdalles Guzman, U., additional, Abad Esttebanez, S., additional, Vega Martinez, A., additional, Barraca, D., additional, Yuste, C., additional, Bucalo, L., additional, Rincon, A., additional, Lopez-Gomez, J. M., additional, Bataille, P., additional, Celine, P., additional, Raymond, A., additional, Francois, G., additional, Herve, L., additional, Michel, D., additional, Jean Louis, R., additional, Zhu, F., additional, Kotanko, P., additional, Thijssen, S., additional, Levin, N. W., additional, Papamichail, N., additional, Bougiakli, M., additional, Gouva, C., additional, Antoniou, S., additional, Gianitsi, S., additional, Vlachopanou, A., additional, Chachalos, S., additional, Naka, K., additional, Kaarsavvidou, D., additional, Katopodis, K., additional, Michalis, L., additional, Sasaki, K., additional, Yasuda, K., additional, Yamato, M., additional, Surace, A., additional, Rovatti, P., additional, Steckiph, D., additional, Bandini, R., additional, Severi, S., additional, Dellacasa Bellingegni, A., additional, Santoro, A., additional, Arias, M., additional, Sentis, A., additional, Perez, N., additional, Fontsere, N., additional, Vera, M., additional, Rodriguez, N., additional, Arcal, C., additional, Ortega, N., additional, Uriza, F., additional, Cases, A., additional, Maduell, F., additional, Abbas, S. R., additional, Georgianos, P., additional, Sarafidis, P., additional, Nikolaidis, P., additional, Lasaridis, A., additional, Ahmed, A., additional, Kaoutar, H., additional, Mohammed, B., additional, Zouhir, O., additional, Balter, P., additional, Ginsberg, N., additional, Taylor, P., additional, Sullivan, T., additional, Usvyat, L. A., additional, Zabetakis, P., additional, Moissl, U., additional, Ferrario, M., additional, Garzotto, F., additional, Wabel, P., additional, Cruz, D., additional, Tetta, C., additional, Signorini, M. G., additional, Cerutti, S., additional, Brendolan, A., additional, Ronco, C., additional, Heaf, J., additional, Axelsen, M., additional, Pedersen, R. S., additional, Amine, H., additional, Oualim, Z., additional, Ammirati, A. L., additional, Guimaraes de Souza, N. K., additional, Nemoto Matsui, T., additional, Luiz Vieira, M., additional, Alves de Oliveira, W. A., additional, Fischer, C. H., additional, Dias Carneiro, F., additional, Iizuka, I. J., additional, Aparecida de Souza, M., additional, Mallet, A. C., additional, Cruz Andreoli, M. C., additional, Cardoso Dos Santos, B. F., additional, Rosales, L., additional, Dou, Y., additional, Carter, M., additional, Testa, A., additional, Sottini, L., additional, Giacon, B., additional, Prati, E., additional, Loschiavo, C., additional, Brognoli, M., additional, Marseglia, C., additional, Tommasi, A., additional, Sereni, L., additional, Palladino, G., additional, Bove, S., additional, Bosticardo, G., additional, Schillaci, E., additional, Detoma, P., additional, Bergia, R., additional, Park, J. W., additional, Moon, S. J., additional, Choi, H. Y., additional, Ha, S. K., additional, Park, H.-C., additional, Liao, Y., additional, Zhang, L., additional, Fu, P., additional, Igarashi, H., additional, Suzuki, N., additional, Esashi, S., additional, Masakane, I., additional, Panichi, V., additional, De Ferrari, G., additional, Saffiotti, S., additional, Sidoti, A., additional, Biagioli, M., additional, Bianchi, S., additional, Imperiali, P., additional, Gabrielli, C., additional, Conti, P., additional, Patrone, P., additional, Rombola, G., additional, Falqui, V., additional, Mura, C., additional, Icardi, A., additional, Rosati, A., additional, Santori, F., additional, Mannarino, A., additional, Bertucci, A., additional, Jeong, J., additional, Kim, O. K., additional, Kim, N. H., additional, Bots, M., additional, Den Hoedt, C., additional, Grooteman, M. P., additional, Van der Weerd, N. C., additional, Mazairac, A. H. A., additional, Levesque, R., additional, Ter Wee, P. M., additional, Nube, M. J., additional, Blankestijn, P., additional, Van den Dorpel, M. A., additional, Park, Y., additional, Jeon, J., additional, Tessitore, N., additional, Bedogna, V., additional, Girelli, D., additional, Corazza, L., additional, Jacky, P., additional, Guillaume, Q., additional, Julien, B., additional, Marcinkowski, W., additional, Drozdz, M., additional, Milkowski, A., additional, Rydzynska, T., additional, Prystacki, T., additional, August, R., additional, Benedyk-Lorens, E., additional, Bladek, K., additional, Cina, J., additional, Janiszewska, G., additional, Kaczmarek, A., additional, Lewinska, T., additional, Mendel, M., additional, Paszkot, M., additional, Trafidlo, E., additional, Trzciniecka-Kloczkowska, M., additional, Vasilevsky, A., additional, Konoplev, G., additional, Lopatenko, O., additional, Komashnya, A., additional, Visnevsky, K., additional, Gerasimchuk, R., additional, Neivelt, I., additional, Frorip, A., additional, Vostry, M., additional, Racek, J., additional, Rajdl, D., additional, Eiselt, J., additional, Malanova, L., additional, Pechter, U., additional, Selart, A., additional, Ots-Rosenberg, M., additional, Krieter, D. H., additional, Seidel, S., additional, Merget, K., additional, Lemke, H.-D., additional, Wanner, C., additional, Canaud, B., additional, Rodriguez, A., additional, Morgenroth, A., additional, Von Appen, K., additional, Dragoun, G.-P., additional, Fluck, R., additional, Fouque, D., additional, Lockridge, R., additional, Motomiya, Y., additional, Uji, Y., additional, Hiramatsu, T., additional, Ando, Y., additional, Furuta, M., additional, Kuragano, T., additional, Kida, A., additional, Yahiro, M., additional, Otaki, Y., additional, Hasuike, Y., additional, Nonoguchi, H., additional, Nakanishi, T., additional, Sain, M., additional, Kovacic, V., additional, Ljutic, D., additional, Radic, J., additional, Jelicic, I., additional, Yalin, S. F., additional, Trabulus, S., additional, Yalin, A. S., additional, Altiparmak, M. R., additional, Serdengecti, K., additional, Ohtsuka, A., additional, Fukami, K., additional, Ishikawa, K., additional, Ando, R., additional, Kaida, Y., additional, Adachi, T., additional, Sugi, K., additional, Okuda, S., additional, Nesterova, O. B., additional, Suglobova, E. D., additional, Golubev, R. V., additional, Vasiliev, A. N., additional, Lazeba, V. A., additional, Smirnov, A. V., additional, Arita, K., additional, Kihara, E., additional, Maeda, K., additional, Oda, H., additional, Doi, S., additional, Masaki, T., additional, Hidaka, S., additional, Ishioka, K., additional, Oka, M., additional, Moriya, H., additional, Ohtake, T., additional, Nomura, S., additional, Kobayashi, S., additional, Wagner, S., additional, Gmerek, A., additional, Wagner, J., additional, Wizemann, V., additional, Eftimovska - Otovic, N., additional, Spaseska-Gjurovska, K., additional, Bogdanovska, S., additional, Babalj - Banskolieva, E., additional, Milovanceva, M., additional, Grozdanovski, R., additional, Pisani, A., additional, Riccio, E., additional, Mancini, A., additional, Ambuhl, P., additional, Astrid, S., additional, Ivana, P., additional, Martin, H., additional, Thomas, K., additional, Hans-Rudolf, R., additional, Daniel, A., additional, Denes, K., additional, Marco, M., additional, Wuthrich, R. P., additional, Andreas, S., additional, Andrulli, S., additional, Altieri, P., additional, Sau, G., additional, Bolasco, P., additional, Pedrini, L. A., additional, Basile, C., additional, David, S., additional, Feriani, M., additional, Nebiolo, P. E., additional, Ferrara, R., additional, Casu, D., additional, Logias, F., additional, Tarchini, R., additional, Cadinu, F., additional, Passaghe, M., additional, Fundoni, G., additional, Villa, G., additional, DI Iorio, B. R., additional, Zoccali, C., additional, Locatelli, F., additional, Hamamoto, M., additional, Lee, D.-Y., additional, Kim, B., additional, Moon, K. H., additional, LI, Z., additional, Ahrenholz, P., additional, Winkler, R. E., additional, Waitz, G., additional, Wolf, H., additional, Grundstrom, G., additional, Alquist, M., additional, Holmquist, M., additional, Christensson, A., additional, Bjork, P., additional, Abdgawad, M., additional, Ekholm, L., additional, Segelmark, M., additional, Corsi, C., additional, De Bie, J., additional, Mambelli, E., additional, Mortara, D., additional, Arroyo, D., additional, Panizo, N., additional, Quiroga, B., additional, Reque, J., additional, Melero, R., additional, Rodriguez-Ferrero, M., additional, Rodriguez-Benitez, P., additional, Anaya, F., additional, Luno, J., additional, Ragon, A., additional, James, A., additional, Brunet, P., additional, Ribeiro, S., additional, Faria, M. S., additional, Rocha, S., additional, Rodrigues, S., additional, Catarino, C., additional, Reis, F., additional, Nascimento, H., additional, Fernandes, J., additional, Miranda, V., additional, Quintanilha, A., additional, Belo, L., additional, Costa, E., additional, Santos-Silva, A., additional, Arund, J., additional, Tanner, R., additional, Fridolin, I., additional, Luman, M., additional, Clajus, C., additional, Kielstein, J. T., additional, Haller, H., additional, Libutti, P., additional, Lisi, P., additional, Vernaglione, L., additional, Casucci, F., additional, Losurdo, N., additional, Teutonico, A., additional, Lomonte, C., additional, Krisp, C., additional, Wolters, D. A., additional, Matsuyama, M., additional, Tomo, T., additional, Ishida, K., additional, Matsuyama, K., additional, Nakata, T., additional, Kadota, J., additional, Caiazzo, M., additional, Monari, E., additional, Cuoghi, A., additional, Bellei, E., additional, Bergamini, S., additional, Tomasi, A., additional, Baranger, T., additional, Seniuta, P., additional, Berge, F., additional, Drouillat, V., additional, Frangie, C., additional, Rosier, E., additional, Labonia, W., additional, Lescano, A., additional, Rubio, D., additional, Von der Lippe, N., additional, Jorgensen, J. A., additional, Osthus, T. B., additional, Waldum, B., additional, Os, I., additional, Bossola, M., additional, DI Stasio, E., additional, Antocicco, M., additional, Tazza, L., additional, Griveas, I., additional, Karameris, A., additional, Pasadakis, P., additional, Savica, V., additional, Santoro, D., additional, Saitta, S., additional, Tigano, V., additional, Bellinghieri, G., additional, Gangemi, S., additional, Daniela, R., additional, Checherita, I. A., additional, Ciocalteu, A., additional, Vacaroiu, I. A., additional, Niculae, A., additional, Stefaniak, E., additional, Pietrzak, I., additional, Krupa, D., additional, Garred, L., additional, Mancini, E., additional, Corrazza, L., additional, Atti, M., additional, Afsar, B., additional, Stamopoulos, D., additional, Mpakirtzi, N., additional, Gogola, B., additional, Zeibekis, M., additional, Stivarou, D., additional, Panagiotou, M., additional, Grapsa, E., additional, Vega Vega, O., additional, Barraca Nunez, D., additional, Fernandez-Lucas, M., additional, Gomis, A., additional, Teruel, J. L., additional, Elias, S., additional, Quereda, C., additional, Hignell, L., additional, Humphrey, S., additional, Pacy, N., additional, and Afentakis, N., additional

Published
2012
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33. The German Chronic Kidney Disease (GCKD) study: design and methods

Author

Eckardt, K.-U., primary, Barthlein, B., additional, Baid-Agrawal, S., additional, Beck, A., additional, Busch, M., additional, Eitner, F., additional, Ekici, A. B., additional, Floege, J., additional, Gefeller, O., additional, Haller, H., additional, Hilge, R., additional, Hilgers, K. F., additional, Kielstein, J. T., additional, Krane, V., additional, Kottgen, A., additional, Kronenberg, F., additional, Oefner, P., additional, Prokosch, H.-U., additional, Reis, A., additional, Schmid, M., additional, Schaeffner, E., additional, Schultheiss, U. T., additional, Seuchter, S. A., additional, Sitter, T., additional, Sommerer, C., additional, Walz, G., additional, Wanner, C., additional, Wolf, G., additional, Zeier, M., additional, and Titze, S., additional

Published
2011
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35. Combination of everolimus with calcineurin inhibitor medication resulted in post-transplant haemolytic uraemic syndrome in lung transplant recipients--a case series

Author

Lovric, S., primary, Kielstein, J. T., additional, Kayser, D., additional, Brocker, V., additional, Becker, J. U., additional, Hiss, M., additional, Schiffer, M., additional, Sommerwerck, U., additional, Haller, H., additional, Struber, M., additional, Welte, T., additional, and Gottlieb, J., additional

Published
2011
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44. Reply

Author

Clajus, C., primary, Becker, J. U., additional, Stichtenoth, D. O., additional, Wortmann, J., additional, Schwarz, A., additional, and Kielstein, J. T., additional

Published
2008
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50. Free serum leptin but not bound leptin concentrations are elevated in patients with end-stage renal disease.

Author

Widjaja, A, Kielstein, J T, Horn, R, von zur Mühlen, A, Kliem, V, and Brabant, G

Abstract

Leptin is a 16-kDa protein that is thought to be a regulator of food intake and body weight. Although total serum leptin levels have been reported to be elevated in obese and normal weight patients with end-stage renal disease (ESRD), it is not known whether serum-free leptin concentrations are also increased in patients with ESRD with no apparent nutritional problems. Furthermore, there are no data on how different dialysis modes (high-flux haemodiafiltration and low-flux dialysis) influence serum leptin subfractions.

Published
2000
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