Search

In the present study, green synthesis of silver nanoparticles (Ag NPs) was synthesized from silver ions using the reducing agents of Catharanthus roseus flowers extract. This flower was extract and fractionated by non-polar to polar solvent using separating funnel. The distilled water fraction was analyses the primary phytochemical test and used the synthesis of NPs. The UV-vis spectra wavelength value at 447 nm was confirmed the product of Ag NPs. FTIR spectrum wavenumbers at 3401 and 1625 cm−1 has indicates the hydroxyl and carbonyl groups, respectively, capping the Ag NPs. HRTEM images of Ag NPs shows the spherical shape with sizes 5–20 nm. This NPs has excellent photocatalyst in the reduction of methyl orange and 4-nitrophenol (4-NP) in the presence of NaBH4. These NPs has potential antioxidant activity of DPPH, and H2O2 assays against the standard ascorbic acid contain the 100 µg/ml of NPs shows 65% and 77% of inhibition activity.

In this present study, green synthesis of silver nanoparticles (AgNPs) was synthesized from silver nitrate using the reducing agents of Polyalthia longifolia bark extract and applied the catalyst in the reduction/degradation of environmental polluted organic compound in the presence of NaBH4. Initially, the colourless reaction mixture was slowly changed to yellowish brown, UV-visible spectroscopy of surface plasmon resonance centre at 447 nm confirmed the formation of AgNPs. High resolution transmission electron microscopy (HRTEM) clearly identified the spherical shapes nanoparticles with diameters sizes 5-25 nm. This AgNPs has excellent catalyst in the catalytic reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP) as compared to the reducing agent of NaBH4 (chemical) and plant extract (natural).

This study reports the ecofriendly economically, and environmentally benign approach for synthesizing silver nanoparticles using the traditional medicinal herb Pedalium murex mucilage. It���s structural, compositional, antibacterial, and antioxidant in vitro biological activity and solar-driven photocatalytic methylene blue dye degradation characterization were investigated. FTIR analysis showed many active sites providing functional groups and their possible role in reducing and capping activity. The P. murex mucilage synthesized and capped AgNPs exhibited 437 nm UV ���Vis. peak absorption, 25���45 nm size, spherical shape with significant antibacterial, antioxidant and visible light photocatalytic methylene blue dye (87.13%) in 150 min. The higher biological activity results boost large-scale production of the synthesized silver nanoparticles for many applications.

Rosmarinic acid is a polyphenolic phytoconstituent isolated from the leaves of Plectranthus amboinicus and its structure was established by analysis of its 1H, 13C and HRMS. The effect of rosmarinic acid was evaluated by deranged plasma and tissues glycoprotein components in diabetic rats. Rosmarinic acid was administered to diabetic rats for 30 days significantly declined the levels of blood glucose and glycosylated haemoglobin with elevation of plasma insulin and haemoglobin levels. Rosmarinic acid administration improved the glycogen content in liver and muscle tissue by reinstating the altered glycogen metabolic enzymes such as glycogen synthase and glycogen phosphorylase. Further, the altered levels of plasma and tissue glycoprotein components were restored to near normal upon treatment with rosmarinic acid. In addition, rosmarinic acid treatment prevented body weight loss and excessive intake of food and water. The effect produced by the rosmarinic acid on various parameters was comparable to that of metformin.

The present study was aimed to explore the antihyperlipidemic and anti-inflammatory effect of acyclic isoprenoid on high fat diet fed rats. Hypercholesterolemia was induced by the diet comprising of the normal rat chow 84.3%, lard 5%, yolk powder 10%, cholesterol 0.2% and 0.5% bile salt were fed to the rats for the period of 8 weeks. The results showed that abnormally elevated levels of plasma lipid profiles. Three different doses of acyclic isoprenoid (20, 40 and 80 mg/kg b.w/day) were administered orally to hypercholesterolemia suffering rats for the period of 30 days. Among these three doses of acyclic isoprenoid, the dose 80 mg/kg b.w. was significantly decreased the plasma lipid profiles when compared to other two doses. The effect produced by acyclic isoprenoid (80 mg/kg b.w) was comparable to that of simvastatin. Therefore, 80 mg/kg b.w was fixed as a effective dose and used for further analyses. Acyclic isoprenoid administration reinstated the elevated levels of cardiac and inflammatory markers in both blood and serum of hypercholesterolemic rats. In addition, acyclic isoprenoid administration decreased activity of 3-hydroxy 3-methyl-glutaryl-CoA reductase and increased the activity of lecithin cholesterol acyl transferase. These findings suggest that the administration of acyclic isoprenoid was potentially ameliorated the cardiac marker enzymes and inflammatory markers in addition to its antihypercholesterolemic effect.