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38. Comparison of Clinical Characteristics and Risk Factors for Recurrence of Kikuchi–Fujimoto Disease Between Children and Adult

Author

Baek,Jee Yeon, Kang,Ji-Man, Lee,Ji Young, Lim,Sung Min, Ahn,Jong Gyun, Baek,Jee Yeon, Kang,Ji-Man, Lee,Ji Young, Lim,Sung Min, and Ahn,Jong Gyun

Abstract

Jee Yeon Baek,1 Ji-Man Kang,1,2 Ji Young Lee,1 Sung Min Lim,1 Jong Gyun Ahn1,2 1Department of Pediatrics, Severance Children’s Hospital, Yonsei University College of Medicine, Seoul, Korea; 2Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, KoreaCorrespondence: Jong Gyun Ahn, Department of Pediatrics, Severance Children’s Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea, Tel +82-2-2228-2057, Fax +82-2-393-9118, Email JGAHN@yuhs.acPurpose: Kikuchi–Fujimoto disease (KFD) is a rare, benign, and self-limited disease, characterized by cervical lymphadenopathy and fever. Herein, we analyzed the differences in its clinical manifestations and risk factors for recurrence between children and adults.Patients and Methods: We retrospectively reviewed the medical records of patients diagnosed with KFD at a tertiary referral hospital between 2005 and 2019. Patients were divided into two groups based on their age: children (< 19 years) and adults (≥ 19 years).Results: During the 14-year study period, 127 patients were diagnosed with KFD. Among these, 34 (26.8%) were children and 93 (73.2%) were adults. The fever duration was longer and the frequency of myalgia was higher in adults than in children; however, no other significant symptomatic differences were noted between the two groups. Lymph node evaluation was mainly performed using ultrasound in children (61.8%) and computed tomography in adults (78.5%). Moreover, the frequency of antibiotic use was higher in children than in adults (76.5% vs 54.8%, P = 0.027). In adults, multivariable logistic regression analysis revealed anti-nuclear antibody (ANA) positivity (titer ≥ 1:80) as a risk factor for recurrence (odds ratio: 7.813; 95% confidence interval = 1.818– 33.333; P = 0.006).Conclusion: The clinical features of KFD in children and adults were similar; however, the preferred imaging study and frequency of antibioti

Published
2022

39. Reduction in Kawasaki Disease After Nonpharmaceutical Interventions in the COVID-19 Era

Author

Kang, Ji-Man, Kim, Young-Eun, Huh, Kyungmin, Hong, Jinwook, Kim, Dong Wook, Kim, Min Young, Jung, Se Yong, Kim, Jong-Hun, Jung, Jaehun, and Ahn, Jong Gyun

Subjects
Male, Kawasaki disease, Adolescent, Infant, Newborn, COVID-19, Infant, Mucocutaneous Lymph Node Syndrome, Young Adult, Child, Preschool, Correspondence, Republic of Korea, Research Letter, incidence, Humans, Female, physical distancing, Child, Retrospective Studies
Published
2021

50. Successful Sirolimus Treatment for Korean Patients with Activated Phosphoinositide 3-kinase δ Syndrome 1: the First Case Series in Korea

Author

Kang, Ji-Man, primary, Kim, Su Kyung, additional, Kim, Dongsub, additional, Choi, Sae Rom, additional, Lim, Yeon Jung, additional, Kim, Soon Ki, additional, Park, Byung-Kiu, additional, Park, Weon Seo, additional, Kang, Eun-Suk, additional, Ko, Young Hyeh, additional, Choe, Yon Ho, additional, Lee, Ji Won, additional, and Kim, Yae-Jean, additional

Published
2020
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