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5 results on '"K Kätzner"'

1. Description of measles D4-Hamburg outbreak in Hamburg, Germany, December 2008 to June 2009, which disproportionally affected a local Roma community

Author

G, Hegasy, K, Kätzner, M, Helle, A, Mankertz, S, Baumgarte, A, Wille, and G, Fell

Subjects
Adult, Male, Travel, Chi-Square Distribution, Adolescent, Measles Vaccine, Infant, Medically Underserved Area, Middle Aged, Polymerase Chain Reaction, Disease Outbreaks, Young Adult, Age Distribution, Catchment Area, Health, Measles virus, Child, Preschool, Germany, Population Surveillance, Humans, Female, Immunization, Child, Disease Notification, Measles
Abstract

From December 2008 to June 2009 a measles outbreak occurred in the Federal State of Hamburg, Germany. The outbreak affected 216 persons and was caused by a new measles strain termed D4-Hamburg which led to consecutive outbreaks between 2009 and 2011 in at least 12 European countries. Here, we describe epidemiological characteristics of the outbreak and evaluate the control measures taken in Hamburg. In one of the seven boroughs of Hamburg a local Roma community comprised more than 50% of the notified cases.We compared in a stratified analysis the age distribution of these cases with cases of fellow citizens who did not belong to the Roma community. The age group of infants (0-11 months) comprised 33% among the non-Roma measles cases, while in the Roma community only 4% belonged to this stratum. In the stratum of 5-17 year-olds only 8% were affected among the non-Roma cases, whereas in the Roma community 50% belonged to this age group. We discuss the influencing factors that might have led to this difference in age distribution between the two groups.

Published
2012

2. Description of measles D4-Hamburg outbreak in Hamburg, Germany, December 2008 to June 2009, which disproportionally affected a local Roma community

Author

Guido Hegasy, A. Wille, K. Kätzner, M. Helle, Annette Mankertz, Sigrid Baumgarte, and G. Fell

Subjects
Pediatrics, medicine.medical_specialty, Epidemiology, Public Health, Environmental and Occupational Health, Outbreak, Measles outbreak, medicine.disease, Measles, Stratified analysis, Geography, Virology, medicine, Age distribution, Demography, Federal state
Abstract

From December 2008 to June 2009 a measles outbreak occurred in the Federal State of Hamburg, Germany. The outbreak affected 216 persons and was caused by a new measles strain termed D4-Hamburg which led to consecutive outbreaks between 2009 and 2011 in at least 12 European countries. Here, we describe epidemiological characteristics of the outbreak and evaluate the control measures taken in Hamburg. In one of the seven boroughs of Hamburg a local Roma community comprised more than 50% of the notified cases. We compared in a stratified analysis the age distribution of these cases with cases of fellow citizens who did not belong to the Roma community. The age group of infants (0-11 months) comprised 33% among the non-Roma measles cases, while in the Roma community only 4% belonged to this stratum. In the stratum of 5-17 year-olds only 8% were affected among the non-Roma cases, whereas in the Roma community 50% belonged to this age group. We discuss the influencing factors that might have led to this difference in age distribution between the two groups.

Published
2012
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3. Evidence for limited humoral immunoglobulin M antibody response to hepatitis B core antigen during acute and chronic hepatitis B virus infections

Author

R Laufs, C H Granato, K Kätzner, and E. G. Lindenschmidt

Subjects
Microbiology (medical), Time Factors, Hepatitis B virus DNA polymerase, Metabolic Clearance Rate, Fluorescent Antibody Technique, Viremia, Enzyme-Linked Immunosorbent Assay, Virus, Antigen, medicine, Humans, Hepatitis B Antibodies, Hepatitis, biology, business.industry, Hepatitis B, medicine.disease, Virology, Hepatitis B Core Antigens, Immunoglobulin M, Immunology, Chronic Disease, biology.protein, Antibody, business, Research Article
Abstract

The periods of persisting immunoglobulin M class antibodies to hepatitis B core antigen in 28 patients with acute hepatitis B infections and in 134 patients with chronic hepatitis B infections were studied by using an enzyme-linked immunosorbent assay and an indirect immunofluorescence technique. We showed that the clearance of antibodies to hepatitis B core antigen is independent of the degree of viremia in both forms of hepatitis.

Published
1985

4. Description of measles D4-Hamburg outbreak in Hamburg, Germany, December 2008 to June 2009, which disproportionally affected a local Roma community.

Author

Hegasy G, Kätzner K, Helle M, Mankertz A, Baumgarte S, Wille A, and Fell G

Subjects
Adolescent, Adult, Age Distribution, Catchment Area, Health, Chi-Square Distribution, Child, Child, Preschool, Disease Notification, Female, Germany epidemiology, Humans, Immunization statistics & numerical data, Infant, Male, Measles diagnosis, Measles immunology, Measles prevention & control, Middle Aged, Polymerase Chain Reaction, Travel, Young Adult, Disease Outbreaks, Measles epidemiology, Measles Vaccine administration & dosage, Measles virus immunology, Medically Underserved Area, Population Surveillance
Abstract

From December 2008 to June 2009 a measles outbreak occurred in the Federal State of Hamburg, Germany. The outbreak affected 216 persons and was caused by a new measles strain termed D4-Hamburg which led to consecutive outbreaks between 2009 and 2011 in at least 12 European countries. Here, we describe epidemiological characteristics of the outbreak and evaluate the control measures taken in Hamburg. In one of the seven boroughs of Hamburg a local Roma community comprised more than 50% of the notified cases.We compared in a stratified analysis the age distribution of these cases with cases of fellow citizens who did not belong to the Roma community. The age group of infants (0-11 months) comprised 33% among the non-Roma measles cases, while in the Roma community only 4% belonged to this stratum. In the stratum of 5-17 year-olds only 8% were affected among the non-Roma cases, whereas in the Roma community 50% belonged to this age group. We discuss the influencing factors that might have led to this difference in age distribution between the two groups.

Published
2012

5. Evidence for limited humoral immunoglobulin M antibody response to hepatitis B core antigen during acute and chronic hepatitis B virus infections.

Author

Lindenschmidt EG, Granato CH, Kätzner K, and Laufs R

Subjects
Chronic Disease, Enzyme-Linked Immunosorbent Assay, Fluorescent Antibody Technique, Hepatitis B microbiology, Humans, Immunoglobulin M metabolism, Metabolic Clearance Rate, Time Factors, Hepatitis B immunology, Hepatitis B Antibodies metabolism, Hepatitis B Core Antigens immunology
Abstract

The periods of persisting immunoglobulin M class antibodies to hepatitis B core antigen in 28 patients with acute hepatitis B infections and in 134 patients with chronic hepatitis B infections were studied by using an enzyme-linked immunosorbent assay and an indirect immunofluorescence technique. We showed that the clearance of antibodies to hepatitis B core antigen is independent of the degree of viremia in both forms of hepatitis.

Published
1985
Full Text
View/download PDF

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