201 results on '"Jonas, Jean-Christophe"'
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2. The lack of functional nicotinamide nucleotide transhydrogenase only moderately contributes to the impairment of glucose tolerance and glucose-stimulated insulin secretion in C57BL/6J vs C57BL/6N mice
3. Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans
4. NNT reverse mode of operation mediates glucose control of mitochondrial NADPH and glutathione redox state in mouse pancreatic β-cells
5. Phlda3 regulates beta cell survival during stress
6. Prolonged culture of human pancreatic islets under glucotoxic conditions changes their acute beta cell calcium and insulin secretion glucose response curves from sigmoid to bell-shaped
7. In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo
8. Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells
9. Identification of a human-specific alteration of beta cell function after prolonged culture of pancreatic islets under glucotoxic conditions
10. Unveiling a common mechanism of apoptosis in β-cells and neurons in Friedreichʼs ataxia
11. MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity
12. Emerging Roles of Metallothioneins in Beta Cell Pathophysiology: Beyond and above Metal Homeostasis and Antioxidant Response
13. HDLs Protect Pancreatic β-Cells Against ER Stress by Restoring Protein Folding and Trafficking
14. Mechanisms of Control of the Free Ca2+ Concentration in the Endoplasmic Reticulum of Mouse Pancreatic β-Cells: Interplay With Cell Metabolism and [Ca2+]c and Role of SERCA2b and SERCA3
15. Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia
16. Probe-Independent and Direct Quantification of Insulin mRNA and Growth Hormone mRNA in Enriched Cell Preparations
17. Mechanisms of Pancreatic β-Cell Death in Type 1 and Type 2 Diabetes: Many Differences, Few Similarities
18. Induction of Adiponectin in Skeletal Muscle by Inflammatory Cytokines: in Vivo and in Vitro Studies
19. Atypical Ca2+-induced Ca2+ release from a sarco-endoplasmic reticulum Ca2+-ATPase 3-dependent Ca2+ pool in mouse pancreatic β-cells
20. SERCA3 Ablation Does Not Impair Insulin Secretion but Suggests Distinct Roles of Different Sarcoendoplasmic Reticulum Ca2+ Pumps for Ca2+ Homeostasis in Pancreatic β-cells
21. Increased Glucose Sensitivity of Stimulus-Secretion Coupling in Islets From Psammomys obesus After Diet Induction of Diabetes
22. Do Oscillations of Insulin Secretion Occur in the Absence of Cytoplasmic Ca2+ Oscillations in β-Cells?
23. Control Mechanisms of the Oscillations of Insulin Secretion In Vitro and In Vivo
24. Signals and Pools Underlying Biphasic Insulin Secretion
25. Increased Expression of Antioxidant and Antiapoptotic Genes in Islets That May Contribute to β-Cell Survival During Chronic Hyperglycemia
26. β-Cell Adaptation to Hyperglycemia
27. Potential Role of the Early Response Gene c-myc in β-Cell Adaptation to Changes in Glucose Concentration
28. Glucose Regulates Expression of Inositol 1,4,5-Trisphosphate Receptor Isoforms in Isolated Rat Pancreatic Islets*
29. Metallothionein 1 inhibits glucose-stimulated insulin secretion and is differentially regulated in conditions of beta cell compensation and failure
30. Possible Links between Glucose-induced Changes in the Energy State of Pancreatic B Cells and Insulin Release: Unmasking by Decreasing a Stable Pool of Adenine Nucleotides in Mouse Islets
31. Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes
32. Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of KATP Channel Blockers
33. Glucolipotoxic conditions induce β-cell iron import, cytosolic ROS formation and apoptosis
34. MicroRNAs contribute to compensatory ß cell expansion during pregnancy and obesity
35. Somatostatin Is Only Partly Required for the Glucagonostatic Effect of Glucose but Is Necessary for the Glucagonostatic Effect of KATP Channel Blockers.
36. Glucokinase activation is beneficial or toxic to cultured rat pancreatic islets depending on the prevailing glucose concentration
37. Mechanisms of control of the free Ca2+ concentration in the endoplasmic reticulum of mouse pancreatic β-cells : interplay with cell metabolism and [Ca2+]c and role of SERCA2b and SERCA3
38. Activation of Protective and Destructive Stress Genes Accompanies Beta Cell Hypertrophy in Hyperglycemic Rats
39. Unveiling a common mechanism of apoptosis in β-cells and neurons in Friedreich's ataxia
40. Role of activating transcription factor 3 in low glucose- and thapsigargin-induced apoptosis in cultured mouse islets
41. Effects of deglycating enzyme Fructosamine-3-kinase gene knockout on pancreatic beta cell glucotoxicity
42. [Effects of an activation controlled by c-MYC transcription on the function and survival of pancreatic cells in mice]
43. High glucose activates hypoxia inducible factors 1 and 2 in cultured rat islets and INS1-E cell monolayers
44. Atypical Ca2+-induced Ca2+ release from a sarco-endoplasmic reticulum Ca2+-ATPase 3-dependent Ca2+ pool in mouse pancreatic beta-cells
45. The Ca2+ -ATPase SERCA3 influences membrane potential and the pattern of cytosolic [Ca2+]i oscillations in glucose-stimulated mouse beta-cells
46. The Islet Estrogen Receptor-α Is Induced by Hyperglycemia and Protects Against Oxidative Stress-Induced Insulin-Deficient Diabetes
47. Atypical mechanisms of Ca2+-release from the endoplasmic reticulum contribute to the cytosolic Ca2+ rise induced by depolarization in mouse ß-cells
48. Rôle possible du gène de réponse précoce c-Myc dans la perte de différenciation et de fonction des cellules beta pancréatiques soumises à une hyperglycémie chronique
49. Protective Antioxidant and Antiapoptotic Effects of ZnCl2 in Rat Pancreatic Islets Cultured in Low and High Glucose Concentrations
50. Glucose-Induced O2 Consumption Activates Hypoxia Inducible Factors 1 and 2 in Rat Insulin-Secreting Pancreatic Beta-Cells
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