1. A portable triboelectric spirometer for wireless pulmonary function monitoring
- Author
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Xu, Qinghao, Fang, Yunsheng, Jing, Qingshen, Hu, Ning, Lin, Ke, Pan, Yifan, Xu, Lin, Gao, Haiqi, Yuan, Ming, Chu, Liang, Ma, Yanwen, Xie, Yannan, Chen, Jun, and Wang, Lianhui
- Subjects
Engineering ,Nanotechnology ,Biomedical Engineering ,Rare Diseases ,Bioengineering ,Clinical Research ,Lung ,Rehabilitation ,Respiratory ,Good Health and Well Being ,Biosensing Techniques ,COVID-19 ,Humans ,SARS-CoV-2 ,Spirometry ,Vital Capacity ,Self-powered sensors ,Triboelectric nanogenerators ,Spirometers ,Pulmonary function tests ,Analytical Chemistry ,Bioinformatics ,Analytical chemistry ,Biomedical engineering - Abstract
Coronavirus disease 2019 (COVID-19) as a severe acute respiratory syndrome infection has spread rapidly across the world since its emergence in 2019 and drastically altered our way of life. Patients who have recovered from COVID-19 may still face persisting respiratory damage from the virus, necessitating long-term supervision after discharge to closely assess pulmonary function during rehabilitation. Therefore, developing portable spirometers for pulmonary function tests is of great significance for convenient home-based monitoring during recovery. Here, we propose a wireless, portable pulmonary function monitor for rehabilitation care after COVID-19. It is composed of a breath-to-electrical (BTE) sensor, a signal processing circuit, and a Bluetooth communication unit. The BTE sensor, with a compact size and light weight of 2.5 cm3 and 1.8 g respectively, is capable of converting respiratory biomechanical motions into considerable electrical signals. The output signal stability is greater than 93% under 35%-81% humidity, which allows for ideal expiration airflow sensing. Through a wireless communication circuit system, the signals can be received by a mobile terminal and processed into important physiological parameters, such as forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC). The FEV1/FVC ratio is then calculated to further evaluate pulmonary function of testers. Through these measurement methods, the acquired pulmonary function parameters are shown to exhibit high accuracy (>97%) in comparison to a commercial spirometer. The practical design of the self-powered flow spirometer presents a low-cost and convenient method for pulmonary function monitoring during rehabilitation from COVID-19.
- Published
- 2021