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Your search keyword '"Jiang, Xiaoqiong"' showing total 13 results
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13 results on '"Jiang, Xiaoqiong"'

6. Apoptotic Bodies Derived from Fibroblast‐Like Cells in Subcutaneous Connective Tissue Inhibit Ferroptosis in Ischaemic Flaps via the miR‐339‐5p/KEAP1/Nrf2 Axis.

Author

Yu, Gaoxiang, Chen, Yijie, Yang, Ningning, Zhang, Haojie, Zhang, Xuzi, Geng, Yibo, Zhao, Jiayi, Chen, Zhuliu, Dong, Chengji, Lin, Lidan, Qi, Jianjun, Zhang, Xuanlong, Jiang, Xiaoqiong, Gao, Weiyang, Cai, Yuepiao, Wang, Xiangyang, Ding, Jian, Xiao, Jian, and Zhou, Kailiang

Subjects
CONNECTIVE tissue cells, APOPTOTIC bodies, AMINO acid sequence, TREATMENT effectiveness, ENDOTHELIAL cells, IDIOPATHIC femoral necrosis
Abstract

Preventing and treating avascular necrosis at the distal end of the flaps are critical to surgery success, but current treatments are not ideal. A recent study shows that apoptotic bodies (ABs) generated near the site of apoptosis can be taken up and promote cell proliferation. The study reveals that ABs derived from fibroblast‐like cells in the subcutaneous connective tissue (FSCT cells) of skin flaps promoted ischaemic flap survival. It is also found that ABs inhibited cell death and oxidative stress and promoted M1‐to‐M2 polarization in macrophages. Transcriptome sequencing and protein level testing demonstrated that ABs promoted ischaemic flap survival in endothelial cells and macrophages by inhibiting ferroptosis via the KEAP1‐Nrf2 axis. Furthermore, microRNA (miR) sequencing data and in vitro and in vivo experiments demonstrated that ABs inhibited KEAP1 by delivering miR‐339‐5p to exert therapeutic effects. In conclusion, FSCT cell‐derived ABs inhibited ferroptosis, promoted the macrophage M1‐to‐M2 transition via the miR‐339‐5p/KEAP1/Nrf2 axis and promoted ischaemic flap survival. These results provide a potential therapeutic strategy to promote ischaemic flap survival by administering ABs. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Use of dental operating microscope in non ⁃surgical endodontic treatment

Author

GAO Yan and JIANG Xiaoqiong

Subjects
Dental operating microscope, Root canal therapy, Minimally invasive endodontics, Instrument sep⁃ aration, Perforation, Medicine
Abstract

Dental operating microscope is recommended to complicated root canal therapy, for it could provide in⁃ creased lighting and superior magnification, so that the survival rate of tooth is highly increased. More refined access of cavity preparation, canal cleaning, shaping and obturating are realized under microscope. This article combined litera⁃ ture reviews with the writers􀆳 clinical experience, and it aims at helping clinicians to improve their ability to more accu⁃rately performance and minimally invasive endodontic procedures, such as locating hidden canals obstructed by calcifi⁃ cations, canals reduced in size, removing materials, reducing ledge formation, apical transportation, and repairing perforations.

Published
2017
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12. Application of Infrared Thermography in Early Warning of Pressure Injury: a Prospective Observational Study

Author

Cai, Fuman, Jiang, Xiaoqiong, Hou, Xiangqing, Wang, Duolao, Wang, Yu, Deng, Haisong, Guo, Hailei, Wang, Haishuang, and Li, Xiaomei

Subjects
qt_160, wx_200, wn_180
Abstract

Aims and objectives\ud To verify the ability of infrared thermography in objectively identifying pressure injury and its application value in the early warning of pressure injury.\ud \ud Background\ud There is subjectivity in assessing the risk of pressure injury as well as diagnosis in clinical settings, which makes early detection and prevention difficult.\ud \ud Design\ud Prospective, cohort study.\ud \ud Method\ud Four hundred and fifteen patients admitted to the adult intensive care units were enrolled by a convenience sampling method, and they received a follow‐up monitoring for 10 days. The risk of pressure injury was assessed via Braden scale, and thermal images of sacral area were obtained by infrared thermal imager once a day. The predictive effects of infrared thermography and Braden scale on pressure injury were compared by the receiver operating characteristic curve from which the optimal cutoff value of skin temperature for predicting pressure injury was determined. The effect of skin temperature on pressure injury was described and compared, using Kaplan‐Meier curve and Cox proportional hazard regression model respectively. We followed STROBE checklist for reporting the study.\ud \ud Results\ud The relative temperature of sacral area was negatively correlated with the risk of pressure injury. The efficiency of infrared thermography for diagnosing pressure injury was better than that of Braden scale. Based on the relative temperature optimal cutoff value (‐0.1°C), Kaplan‐Meier curve and Cox proportional hazard regression model analysis showed the incidence of pressure injury with relative temperature below ‐0.1°C was higher than the group with relative temperature above ‐0.1°C.\ud \ud Conclusions\ud Infrared thermography can objectively and accurately identify local hypothermia warnings of pressure injury before visual recognition. The application of infrared thermography into routine pressure injury risk assessment provides a timely and reliable method for nursing practitioners.\ud \ud Relevance to clinical practice\ud Infrared thermography has great value of clinical application in daily pressure injury assessment. It is of great significance to make a faster and more objective clinical judgment for patients at risk of pressure injury.

Published
2021

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