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Introduction Reconstruction of critical bone defects is challenging. In a substantial subgroup of patients, conventional reconstructive techniques are insufficient. Biodegradable scaffolds have emerged as a novel tissue engineering strategy for critical-sized bone defect reconstruction. A corticoperiosteal flap integrates the hosts’ ability to regenerate bone and permits the creation of a vascular axis for scaffold neo-vascularisation (regenerative matching axial vascularisation—RMAV). This phase IIa study evaluates the application of the RMAV approach alongside a custom medical-grade polycaprolactone-tricalcium phosphate (mPCL-TCP) scaffold (Osteopore) to regenerate bone sufficient to heal critical size defects in lower limb defects.Methods and analysis This open-label, single-arm feasibility trial will be jointly coordinated by the Complex Lower Limb Clinic (CLLC) at the Princess Alexandra Hospital in Woolloongabba (Queensland, Australia), the Australian Centre for Complex Integrated Surgical Solutions (Queensland, Australia) and the Faculty of Engineering, Queensland University of Technology in Kelvin Grove (Queensland, Australia). Aiming for limb salvage, the study population (n=10) includes any patient referred to the CLLC with a critical-sized bone defect not amenable to conventional reconstructive approaches, after discussion by the interdisciplinary team. All patients will receive treatment using the RMAV approach using a custom mPCL-TCP implant. The primary study endpoint will be safety and tolerability of the reconstruction. Secondary end points include time to bone union and weight-bearing status on the treated limb. Results of this trial will help shape the role of scaffold-guided bone regenerative approaches in complex lower limb reconstruction where current options remain limited.Ethics and dissemination Approval was obtained from the Human Research Ethics Committee at the participating centre. Results will be submitted for publication in a peer-reviewed journal.Trial registration number ACTRN12620001007921.

**Background:** Skin cancer is a relatively common cancer in Australia with early diagnosis and simple treatment conferring a high likelihood of cure. The aim of this study was to implement a ‘see-and-treat’ clinic, using pre-existing infrastructure, to investigate whether this model of care would reduce waiting times and costs and give high levels of patient satisfaction. **Methods:** Inclusion and exclusion criteria based on suitability for day surgery treatment eligibility were developed in consultation with the hospital’s specialist anaesthetic service. Referrals were screened and those eligible underwent consultation with a plastic and reconstructive surgeon and same-day operative management with their choice of anaesthesia. Patients were reviewed one week and four weeks postoperatively. **Results:** Two hundred and six patients had 286 skin lesions removed over 23 operating lists. Over 75 per cent of excisions were on the face. Local anaesthetic with sedation was the most popular anaesthetic technique. There were 22 complications, and the incomplete excision rate was 4.2 per cent. The average waiting time for suitable patients reduced by 76 per cent, and category I outpatient waitlists were reduced by 100 per cent. An estimated gross saving of AU$1339 per patient was calculated. A survey of patients postoperatively showed all patients would recommend this model. **Conclusion:** This’ see-and-treat’ model was shown to reduce waiting times and costs and provide high levels of patient satisfaction. It was also easily implemented using pre-existing infrastructure. It is a service that continues to be offered and expanded, with ongoing patient satisfaction.

This case report describes the management of a 27-year-old male who, after a quadbike accident, presented with an open, infected, segmental both bone forearm injury with significant bone and soft tissue loss including the radio-carpal joint. Limb salvage was accomplished in the form of a single bone forearm fusion utilising Masquelet's two-stage induced membrane technique to reconstruct the segmental bone defect. The patient proceeded to uneventful bony union by 6 months and returned to driving and riding a quadbike. Despite significant deep infection, successful salvage was achieved using the induced membrane technique. Critical to success was aggressive, repeated debridement alongside restoration of vascular supply and reconstruction of soft tissue defects. We highlight the multidisciplinary approach to management including relevant specialists with a particular interest in limb reconstruction.