239 results on '"Ishiura, Shoichi"'
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2. Splicing of human chloride channel 1
3. Suppressor Mutations for Presenilin 1 Familial Alzheimer Disease Mutants Modulate γ-Secretase Activities
4. Functional analysis of SERCA1b, a highly expressed SERCA1 variant in myotonic dystrophy type 1 muscle
5. Usefulness of Monitoring γ-H2AX and Cell Cycle Arrest in HepG2 Cells for Estimating Genotoxicity Using a High-Content Analysis System
6. BMP4 induction of trophoblast from mouse embryonic stem cells in defined culture conditions on laminin
7. Molecular Links among the Causative Genes for Ocular Malformation: Otx2 and Sox2 Coregulate Rax Expression
8. Comparison of Presenilin 1 and Presenilin 2 γ-Secretase Activities Using a Yeast Reconstitution System
9. β-Secretase Inhibitor Potency Is Decreased by Aberrant β-Cleavage Location of the “Swedish Mutant” Amyloid Precursor Protein
10. Production of the herb Ruta chalepensis L. expressing amyloid β-GFP fusion protein
11. Nuclear localization of MBNL1: splicing-mediated autoregulation and repression of repeat-derived aberrant proteins
12. ABLIM1 splicing is abnormal in skeletal muscle of patients with DM1 and regulated by MBNL, CELF and PTBP1
13. Nicastrin Is Dispensable for γ-Secretase Protease Activity in the Presence of Specific Presenilin Mutations
14. Dystrophin Diagnosis: Comparison of Dystrophin Abnormalities by Immunofluorescence and Immunoblot Analyses
15. Aβ46 Is Processed to Aβ40 and Aβ43, but Not to Aβ42, in the Low Density Membrane Domains
16. Distant N- and C-terminal Domains Are Required for Intrinsic Kinase Activity of SMG-1, a Critical Component of Nonsense-mediated mRNA Decay
17. Metabolism of amyloid precursor protein in COS cells transfected with a β-secretase candidate
18. Alternative splicing of myomesin 1 gene is aberrantly regulated in myotonic dystrophy type 1
19. MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1
20. Polyalanine tracts directly induce the release of cytochrome c, independently of the mitochondrial permeability transition pore, leading to apoptosis
21. Endoplasmic reticulum stress caused by aggregate-prone proteins containing homopolymeric amino acids
22. Interactions between homopolymeric amino acids (HPAAs)
23. Intracellular Localization of Homopolymeric Amino Acid-containing Proteins Expressed in Mammalian Cells
24. Potential Link between Amyloid β-Protein 42 and C-terminal Fragment γ 49–99 of β-Amyloid Precursor Protein
25. Plant-based vaccines for Alzheimer’s disease
26. RGB‐Color intensiometric indicators to visualize spatiotemporal dynamics of ATP in single cells
27. Data describing the effect of DRD4 promoter polymorphisms on promoter activity
28. Splicing misregulation of SCN5A contributes to cardiac-conduction delay and heart arrhythmia in myotonic dystrophy
29. ABLIM1splicing is abnormal in skeletal muscle of patients with DM1 and regulated by MBNL, CELF and PTBP1
30. Nuclear localization of MBNL1: splicing-mediated autoregulation and repression of repeat-derived aberrant proteins
31. Dopamine Modulates Acetylcholine Release via Octopamine and CREB Signaling in Caenorhabditis elegans
32. Ultrasound-enhanced delivery of Morpholino with Bubble liposomes ameliorates the myotonia of myotonic dystrophy model mice
33. Manumycin A corrects aberrant splicing of Clcn1 in myotonic dystrophy type 1 (DM1) mice
34. BACE1 Inhibitor Peptides: Can an Infinitely Small kcat Value Turn the Substrate of an Enzyme into Its Inhibitor?
35. Production of Anti-Amyloid β Antibodies in Mice Fed Rice Expressing Amyloid β
36. Transgenic Rice Expressing Amyloid β-peptide for Oral Immunization
37. Alcoholism and Alternative Splicing of Candidate Genes
38. BMP4 induction of trophoblast from mouse embryonic stem cells in defined culture conditions on laminin
39. Polyalanine tracts directly induce the release of cytochromec, independently of the mitochondrial permeability transition pore, leading to apoptosis
40. Dysbindin-1, a Schizophrenia-Related Protein, Functionally Interacts with the DNA- Dependent Protein Kinase Complex in an Isoform-Dependent Manner
41. Consideration about negative controls for LC3 and expression vectors for four colored fluorescent protein-LC3 negative controls
42. Autolysis of Calpain Large Subunit Inducing Irreversible Dissociation of Stoichiometric Heterodimer of Calpain
43. Molecular interactions between presenilin and calpain: inhibition of m-calpain protease activity by presenilin and cleavage of presenilin-1 by calpain
44. Immunostaining of skeletal and cardiac muscle surface membrane with antibody against Duchenne muscular dystrophy peptide
45. Membrane-anchored metalloprotease MDC9 has an α-secretase activity responsible for processing the amyloid precursor protein
46. Aspergillus oryzae palBory encodes a calpain-like protease: Homology to Emericella nidulans PalB and conservation of functional regions
47. A Novel Gene that is Activated by Myotonin Protein Kinase (MtPK)
48. The deletion of the C-terminal tail and addition of an endoplasmic reticulum targeting signal to Alzheimer's amyloid precursor protein change its localization, secretion, and intracellular proteolysis
49. Purification of native p94, a muscle-specific calpain, and characterization of its autolysis
50. Functional Defects of a Muscle-specific Calpain, p94, Caused by Mutations Associated with Limb-Girdle Muscular Dystrophy Type 2A
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