252 results on '"Hussain, Sabah N. A."'
Search Results
2. Oxidants Regulated Diaphragm Proteolysis during Mechanical Ventilation in Rats
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Moroz, Nikolay, Maes, Karen, Leduc-Gaudet, Jean-Philippe, Goldberg, Peter, Petrof, Basil J., Mayaki, Dominique, Vassilakopoulos, Theodoros, Rassier, Dilson, Gayan-Ramirez, Ghislaine, and Hussain, Sabah N.
- Published
- 2019
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3. Depletion of HuR in murine skeletal muscle enhances exercise endurance and prevents cancer-induced muscle atrophy
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Janice Sánchez, Brenda, Tremblay, Anne-Marie K., Leduc-Gaudet, Jean-Philippe, Hall, Derek T., Kovacs, Erzsebet, Ma, Jennifer F., Mubaid, Souad, Hallauer, Patricia L., Phillips, Brittany L., Vest, Katherine E., Corbett, Anita H., Kontoyiannis, Dimitris L., Hussain, Sabah N. A., Hastings, Kenneth E. M., Di Marco, Sergio, and Gallouzi, Imed-Eddine
- Published
- 2019
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4. Mechanical ventilation causes diaphragm dysfunction in newborn lambs
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Liang, Feng, Emeriaud, Guillaume, Rassier, Dilson E., Shang, Dong, Gusev, Ekaterina, Hussain, Sabah N. A., Sage, Michael, Crulli, Benjamin, Fortin-Pellerin, Etienne, Praud, Jean-Paul, and Petrof, Basil J.
- Published
- 2019
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5. The impact of high fat feeding and Parkin overexpression on skeletal muscle mass, mitochondrial respiration and H2O2 emission
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Reynaud, Olivier, primary, Wang, Jennifer, additional, Ayoub, Marie-Belle, additional, Leduc-Gaudet, Jean-Philippe, additional, Mayaki, Dominique, additional, Dulac, Maude, additional, Hussain, Sabah N. A., additional, Bergeron, Raynald, additional, and Gouspillou, Gilles, additional
- Published
- 2022
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6. Characterization of skeletal muscle wasting pathways in diaphragm and limb muscles of cystic fibrosis mice
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Gusev, Ekaterina, primary, Liang, Feng, additional, Bhattarai, Salyan, additional, Broering, Felipe E., additional, Leduc-Gaudet, Jean-Philippe, additional, Hussain, Sabah N., additional, Radzioch, Danuta, additional, and Petrof, Basil J., additional
- Published
- 2022
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7. Role of Human Antigen R (HuR) in the Regulation of Pulmonary ACE2 Expression
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Aloufi, Noof, primary, Haidar, Zahraa, additional, Ding, Jun, additional, Nair, Parameswaran, additional, Benedetti, Andrea, additional, Eidelman, David H., additional, Gallouzi, Imed-Eddine, additional, Di Marco, Sergio, additional, Hussain, Sabah N., additional, and Baglole, Carolyn J., additional
- Published
- 2021
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8. The JAK-STAT Pathway Is Critical in Ventilator-Induced Diaphragm Dysfunction
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Tang, Huibin, Smith, Ira J., Hussain, Sabah N. A., Goldberg, Peter, Lee, Myung, Sugiarto, Sista, Godinez, Guillermo L., Singh, Baljit K., Payan, Donald G., Rando, Thomas A., Kinsella, Todd M., and Shrager, Joseph B.
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- 2014
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9. The impact of high-fat feeding and parkin overexpression on skeletal muscle mass, mitochondrial respiration, and H2O2 emission.
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Reynaud, Olivier, Wang, Jennifer, Ayoub, Marie-Belle, Leduc-Gaudet, Jean-Philippe, Mayaki, Dominique, Dulac, Maude, Hussain, Sabah N. A., Bergeron, Raynald, and Gouspillou, Gilles
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MUSCLE mass ,SKELETAL muscle ,GREEN fluorescent protein ,MITOCHONDRIA ,RESPIRATION ,GENETIC overexpression ,TYPE 2 diabetes - Abstract
Obesity is a major risk factor for developing various health problems, including insulin resistance and type 2 diabetes. Although controversial, accumulation of mitochondrial dysfunction, and notably an increase in mitochondrial reactive oxygen species (ROS) production, was proposed as a key contributor leading to obesity-induced insulin resistance. Here, our goal was to investigate whether Parkin overexpression, a key regulator of the removal of dysfunctional mitochondria through mitophagy, could confer protection against obesity-induced mitochondrial dysfunction. To this end, intramuscular injections of adeno-associated viruses (AAVs) were performed to overexpress Parkin in limb muscle of 6-mo-old mice fed a control diet (CD) or a high-fat diet (HFD) for 12 wk. An AAV-expressing the green fluorescent protein (GFP) was used as control. HFD increased fat mass, altered glycemia, and resulted in insulin resistance. Parkin overexpression resulted in an increase in muscle mass in both CD and HFD mice. In CD mice, Parkin overexpression increased maximal mitochondrial respiration and lowered H
2 O2 emission. HFD increased mitochondrial respiration and, surprisingly, also lowered H2 O2 emission. Parkin overexpression did not significantly impact mitochondrial function in HFD mice. Taken altogether, our results indicate that Parkin overexpression positively impacts muscle and mitochondrial health under basal conditions and challenges the notion that intrinsic mitochondrial dysfunction is involved in the development of insulin resistance caused by high-fat feeding. [ABSTRACT FROM AUTHOR]- Published
- 2023
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10. Long Non-coding RNA Rhabdomyosarcoma 2-Associated Transcript Regulates Angiogenesis in Endothelial Cells
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Alaqeeli, Maha, primary, Mayaki, Dominique, additional, and Hussain, Sabah N. A., additional
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- 2021
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11. Mitochondrial Dynamics and Mitophagy in Skeletal Muscle Health and Aging
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Leduc-Gaudet, Jean-Philippe, primary, Hussain, Sabah N. A., additional, Barreiro, Esther, additional, and Gouspillou, Gilles, additional
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- 2021
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12. ETS1, ELK1, and ETV4 Transcription Factors Regulate Angiopoietin-1 Signaling and the Angiogenic Response in Endothelial Cells
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Harel, Sharon, primary, Sanchez, Veronica, additional, Moamer, Alaa, additional, Sanchez-Galan, Javier E., additional, Abid Hussein, Mohammad N., additional, Mayaki, Dominique, additional, Blanchette, Mathieu, additional, and Hussain, Sabah N. A., additional
- Published
- 2021
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13. Editorial: Autophagy and Mitophagy in Skeletal Muscle Health and Disease
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Hussain, Sabah N. A., primary, Sandri, Marco, additional, and Gouspillou, Gilles, additional
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- 2021
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14. An Official American Thoracic Society/European Respiratory Society Statement: Update on Limb Muscle Dysfunction in Chronic Obstructive Pulmonary Disease
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Maltais, François, Decramer, Marc, Casaburi, Richard, Barreiro, Esther, Burelle, Yan, Debigaré, Richard, Dekhuijzen, Richard P. N., Franssen, Frits, Gayan-Ramirez, Ghislaine, Gea, Joaquim, Gosker, Harry R., Gosselink, Rik, Hayot, Maurice, Hussain, Sabah N. A., Janssens, Wim, Polkey, Micheal I., Roca, Josep, Saey, Didier, Schols, Annemie M. W. J., Spruit, Martijn A., Steiner, Michael, Taivassalo, Tanja, Troosters, Thierry, Vogiatzis, Ioannis, and Wagner, Peter D.
- Published
- 2014
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15. Autophagy in Locomotor Muscles of Patients with Chronic Obstructive Pulmonary Disease
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Guo, Yeting, Gosker, Harry R., Schols, Annemie M. W. J., Kapchinsky, Sophia, Bourbeau, Jean, Sandri, Marco, Jagoe, Thomas R., Debigaré, Richard, Maltais, François, Taivassalo, Tanja, and Hussain, Sabah N. A.
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- 2013
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16. Fibulin-5 functions as an endogenous angiogenesis inhibitor
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Sullivan, Kaitlyn M, Bissonnette, Rachel, Yanagisawa, Hiromi, Hussain, Sabah N, and Davis, Elaine C
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- 2007
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17. Angiotensin-converting enzyme 2 expression in COPD and IPF fibroblasts: the forgotten cell in COVID-19
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Aloufi, Noof, primary, Traboulsi, Hussein, additional, Ding, Jun, additional, Fonseca, Gregory J., additional, Nair, Parameswaran, additional, Huang, Steven K., additional, Hussain, Sabah N. A., additional, Eidelman, David H., additional, and Baglole, Carolyn J., additional
- Published
- 2021
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18. Parkin Overexpression Attenuates Sepsis-Induced Muscle Wasting
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Leduc-Gaudet, Jean-Philippe, primary, Mayaki, Dominique, additional, Reynaud, Olivier, additional, Broering, Felipe E., additional, Chaffer, Tomer J., additional, Hussain, Sabah N. A., additional, and Gouspillou, Gilles, additional
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- 2020
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19. Mechanical Ventilation–induced Diaphragm Disuse in Humans Triggers Autophagy
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Hussain, Sabah N. A., Mofarrahi, Mahroo, Sigala, Ioanna, Kim, Ho Cheol, Vassilakopoulos, Theodoros, Maltais, Francois, Bellenis, Ion, Chaturvedi, Rakesh, Gottfried, Stewart B., Metrakos, Peter, Danialou, Gawiyou, Matecki, Stefan, Jaber, Samir, Petrof, Basil J., and Goldberg, Peter
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- 2010
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20. Expression and Functional Significance of Nicotinamide N-methyl Transferase in Skeletal Muscles of Patients with Chronic Obstructive Pulmonary Disease
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Kim, Ho Cheol, Mofarrahi, Mahroo, Vassilakopoulos, Theodoros, Maltais, Francois, Sigala, Ioanna, Debigare, Richard, Bellenis, Ioannis, and Hussain, Sabah N. A.
- Published
- 2010
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21. Oxidative Stress and Respiratory Muscle Dysfunction in Severe Chronic Obstructive Pulmonary Disease
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Barreiro, Esther, de la Puente, Beatriz, Minguella, Joan, Corominas, Josep M., Serrano, Sergi, Hussain, Sabah N. A., and Gea, Joaquim
- Published
- 2005
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22. Protein Carbonyl Formation in the Diaphragm
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Barreiro, Esther, Gea, Joaquim, Di Falco, Marcos, Kriazhev, Leonid, James, Susan, and Hussain, Sabah N. A.
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- 2005
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23. Differential Cytokine Gene Expression in the Diaphragm in Response to Strenuous Resistive Breathing
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Vassilakopoulos, Theodoros, Divangahi, Maziar, Rallis, George, Kishta, Osama, Petrof, Basil, Comtois, Alain, and Hussain, Sabah N. A.
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- 2004
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24. Nitric Oxide Synthases and Protein Oxidation in the Quadriceps Femoris of Patients with Chronic Obstructive Pulmonary Disease
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Barreiro, Esther, Gea, Joaquim, Corominas, Josep M., and Hussain, Sabah N. A.
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- 2003
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25. Superoxide production during sepsis development
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Ritter, Cristiane, Andrades, Michael, Moreira, José Cláudio F., Dal-Pizzol, Felipe, and Hussain, Sabah N. A.
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- 2003
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26. Ventilator-induced Cachexia
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Hussain, Sabah N. A. and Vassilakopoulos, Theodoros
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- 2002
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27. Molecular Characterization of a Superoxide-Generating NAD(P)H Oxidase in the Ventilatory Muscles
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JAVESGHANI, DANESH, MAGDER, SHELDON A., BARREIRO, ESTHER, QUINN, MARK T., and HUSSAIN, SABAH N. A.
- Published
- 2002
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28. Mechanical Ventilation Protects against Diaphragm Injury in Sepsis: Interaction of Oxidative and Mechanical Stresses
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EBIHARA, SATORU, HUSSAIN, SABAH N. A., DANIALOU, GAWIYOU, CHO, WON-KYUNG, GOTTFRIED, STEWART B., and PETROF, BASIL J.
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- 2002
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29. Lipopolysaccharide-induced Diaphragmatic Contractile Dysfunction and Sarcolemmal Injury in Mice Lacking the Neuronal Nitric Oxide Synthase
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COMTOIS, ALAIN S., BARREIRO, ESTHER, HUANG, PAUL L., MARETTE, ANDRÉ, PERRAULT, MYLÈNE, and HUSSAIN, SABAH N. A.
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- 2001
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30. Endothelin Receptor Blockade Attenuates Lipopolysaccharide-induced Pulmonary Nitric Oxide Production
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FUJII, YOSHITAKA, MAGDER, SHELDON, CERNACEK, PETER, GOLDBERG, PETER, GUO, YANG, and HUSSAIN, SABAH N. A.
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- 2000
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31. Lipopolysaccharide-induced Diaphragmatic Contractile Dysfunction in Mice Lacking the Inducible Nitric Oxide Synthase
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COMTOIS, ALAIN S., EL-DWAIRI, QASIM, LAUBACH, VICTOR E., and HUSSAIN, SABAH N. A.
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- 1999
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32. Expression and Regulation of Protein Inhibitor of Neuronal Nitric Oxide Synthase in Ventilatory Muscles
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Guo, Yang, Greenwood, Michael T., Petrof, Basil J., and Hussain, Sabah N. A.
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- 1999
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33. Differential regulation of myofibrillar proteins in skeletal muscles of septic mice
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Moarbes, Vanessa, primary, Mayaki, Dominique, additional, Huck, Laurent, additional, Leblanc, Philippe, additional, Vassilakopoulos, Theodoros, additional, Petrof, Basil J., additional, and Hussain, Sabah N. A., additional
- Published
- 2019
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34. Parkin overexpression protects from ageing‐related loss of muscle mass and strength
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Leduc‐Gaudet, Jean‐Philippe, primary, Reynaud, Olivier, additional, Hussain, Sabah N., additional, and Gouspillou, Gilles, additional
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- 2019
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35. Role of Inducible Nitric Oxide Synthase in Endotoxin-induced Acute Lung Injury
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KRISTOF, ARNOLD S., GOLDBERG, PETER, LAUBACH, VICTOR, and HUSSAIN, SABAH N. A.
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- 1998
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36. Diaphragm Sarcolemmal Injury Is Induced by Sepsis and Alleviated by Nitric Oxide Synthase Inhibition
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LIN, MENG-CHIH, EBIHARA, SATORU, EL DWAIRI, QASIM, HUSSAIN, SABAH N. A., YANG, LIYING, GOTTFRIED, STEWART B., COMTOIS, ALAIN, and PETROF, BASIL J.
- Published
- 1998
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37. Production of Endothelins by the Ventilatory Muscles in Septic Shock
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Guo, Yang, Cernacek, Peter, Giaid, Adel, and Hussain, Sabah N. A.
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- 1998
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38. Contribution of Macrophages to Pulmonary Nitric Oxide Production in Septic Shock
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FUJII, YOSHITAKA, GOLDBERG, PETER, and HUSSAIN, SABAH N. A.
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- 1998
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39. Expression of Nitric Oxide Synthases and GTP Cyclohydrolase I in the Ventilatory and Limb Muscles During Endotoxemia
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Hussain, Sabah N. A., Giaid, Adel, Dawiri, Qassim El, Sakkal, Dalia, Hattori, Ryuichi, and Guo, Yang
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- 1997
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40. 1-03 Role of Activin A in human cancer cachexia (ACTICA study)
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Baracos, Vickie, Muscaritoli, Maurizio, Aversa, Zaira, Rossi Fanelli, Filippo, Loumaye, A, de Barsy, M, Nachit, M, Frateur, L, Lause, P, Van Maanen, A, Thissen, JP, Awasthi, R, Gillis, C, Liberman, S, Stein, B, Charlebois, P, Carli, F, Ahmad, Sultan, Chiche, Dan, Reza Kazemi-Bajestani, Seyyed Mohammad, Becher, Harald, Venner, Peter, North, Scott, Vickie, Baracos, Li, Yi-Ping, Zhang, Guohua, Ma, Jennifer, Hall, Derek, Patel, Devang, Robinson, Samantha, Di Marco, Sergio, Gallouzi, Imed-Eddine, Sartori, Roberta, Penna, Fabio, Costelli, Paola, Sandri, Marco, Gregorevic, Paul, Toth, Michael J, Miller, Mark S, Callahan, Damien M, Couch, Marion E, Dittus, Kim, Sharma, Mridula, Argilés, Josep M, Bedard, N, Wiles, B, Jammoul, S, Miao, M, Wykes, L, Coyne, E, Hallauer, PL, Hastings, KEM, Stretch, C, Baracos, VE, Chevalier, S, Wing, SS, Marchildon, François, Lala, Neena, St-Louis, Catherine, Wiper-Bergeron, Nadine, Santos Silva, Kleiton Augusto, Dong, Jiangling, Tweardy, David J, Mitch, William E, Zhang, Liping, Hall, Derek T, Ma, Jennifer F, Griss, Takla, Jones, Russell G, Marco, Sergio Di, Marks, Daniel L, Rudnicki, Michael A, Laine, Aaron, Narayanan, Sriram, Choy, Hak, Girard, Luc, Gazdar, Adi, Minna, John, Infante, Rodney, Iyengar, Puneeth, Petruzzelli, Michele, Schweiger, Martina, Rincon, Mercedes, Robertson, Graham, Zechner, Rudolf, Wagner, Erwin F, Pin, Fabrizio, Costamagna, Domiziana, Camperi, Andrea, Sampaolesi, Maurilio, He, Wei, Talbert, Erin, Londhe, Priya, Bloomston, Mark, Croce, Carlo, Guttridge, Denis, Breit, Samuel N, Tsai, Vicky WW, Manandhar, Rakesh, Lin, Shu, Sainsbury, Amanda, Brown, David A, Ferrara, Michele, Reano, Simone, Angelino, Elia, Sabry, Omar, Filigheddu, Nicoletta, Graziani, Andrea, Tsoli, Maria, Allen, John, Taylor, Ryland, Scwheiger, Martina, Swarbrick, Michael M, Ehteda, Anahid, Miekle, Peter, Molloy, Mark, Waning, David L, Mohammad, Khalid S, Reiken, Steven, Xie, Wenjun, Marks, Andrew R, Guise, Theresa A, Moya, Rosita, Zhao, Chunfang, Davies, Joanna D, Carson, James, Everett Couch, Marion, Stecher, Michael, El Mouelhi, Mohamed, Tseng, Yu-Chou, Kulp, Samuel K, Lai, I-Lu, Hsu, En-Chi, He, Wei A, Frankhouser, David E, Yan, Pearlly S, Mo, Xiaokui, Lesinski, Gregory B, Marcucci, Guido, Guttridge, Denis C, Bekaii-Saab, Tanios, Chen, Ching-Shih, Haddad, AHI Al, Al-Azwani, EK, Mahamoud, Y, Safi, F, Salhat, H El, Malek, JA, Adrian, TE, Fearon, K, Temel, J, Currow, D, Gleich, L, Friend, J, Abernethy, A, Garcia, Jose M, Dubé, A, Patoine, D, Lemire, BB, Thériault, M-E, Ribeiro, F, Debigaré, R, Maltais, F, Smuder, Ashley J, Min, Kisuk, Kwon, Oh-Sung, Wiggs, Michael P, Sollanenk, Kurt J, Christou, Demetra D, Yoo, Jeung-Ki, Hwang, Moon-Hyon, Szeto, Hazel H, Kavazis, Andreas N, Powers, Scott K, Kroenke, Candyce H, Meyerhardt, Jeffrey A, Kwan, Marilyn L, Prado, Carla, Xiao, Jingjie, Weltzien, Erin, Castillo, Adrienne, Caan, Bette J, Guan, Chen, Giles, Kaitlin, Wing, Simon, Mazurak, Vera, Jagoe, R Thomas, Wiles, Benjamin, Miao, Miao, Coyne, Erin, Larose, Louise, Cybulsky, Andrey V, Wing, Simon S, Marino, Francesco Elia, Risbridger, Gail, Gold, Elspeth, Segatto, Marco, Fittipaldi, Raffaella, Caretti, Giuseppina, Lee, Hwabin, Fu, Dechen, Dwarkasing, JT, Boekschoten, MV, Argilès, JM, van Dijk, M, Busquets, S, Penna, F, Toledo, M, Laviano, A, Witkamp, RF, van Norren, K, Bédard, Nathalie, Plourde, Marie, Chevalier, Stéphanie, Lala-Tabbert, Neena, Marchildon, Francois, Torabi, S, Glare, P, Plodkowski, A, Margaron, Yoran, Fernandes, Mathieu, Morales, Delphine, Poydenot, Pauline, Menager, Pauline, Fuchs, Alexandra, Degot, Sébastien, Calore, Federica, Canella, Alessandro, Croce, Carlo M, Srinivasan, Kalayarasan, Pulliparracharuvil, Suprabha, Meyer, Jeffrey, Scherer, Philipp E, Kambadur, Ravi, Martinelli, Giulia B, Talamini, Laura, Previdi, Sara, Piccirillo, Rosanna, Jafri, Syed H, Previgliano, Carlos, Khandelwal, Keerti, Shi, Runhua, Mills, Glenn, Amato, Robert, Coats, Valérie, Ribeiro, Fernanda, Tremblay, Lise, Lacasse, Yves, Maltais, François, Saey, Didier, AL Vigano, Antonio, Ciutto, Lorella, Tomasso, Jonathan Di, Kilgour, Robert D, Morais, José A, Borod, Manuel, Almasud, A, Giles, K, Baracos, V, Guan, L, Mazurak, V, Khanuja, Jasleen, Gresham, Gillian, Osipov, Arsen, Tan, Carlyn-Rose, Tuli, Richard, Hendifar, Andrew, Narasimhan, Ashok, Greiner, Russell, Yasui, Yutaka, Bathe, Oliver, Fearon, Kenneth, Damaraju, Sambasivarao, Banh, Taylor, Kliewer, Kara, Hsiao, Yung-Hsuan, Belury, Martha A, Caan, Bette, Quesenberry, Charles, Kwan, Marilyn, Prado, Carla MM, Baracos, Vickie E, Birdsell, Laura, Stuyckens, Kim, Park, Youn Choi, Parekh, Trilok, Sawyer, Michael B, Wu, C, Fernandez, SA, Criswell, T, Chidiac, T, Guttridge, D, Villalona-Calero, M, Bekaii-Saab, T, Khan, Sarah, ALVigano, Antonio, Matos-Neto, EM, Figuerêdo, RG, Camargo, RG, Lima, JDCC, Alves, MJ, Riccardi, D, Alcantara, PS, Pinhata, J, Maximiano, L, Seelaender, M, Lamarche, Émilie, Au, Ernie D, Desai, Aditya P, Koniaris, Leonidas G, Zimmers, Teresa A, Manring, Heather, Weisleder, Noah, Okamura, Heidi, Frankhouser, David, Yan, Pearlly, Tomasso, Jonathan di, Fabbro, Egidio G Del, Davis, Mellar P, Fearon, Kenneth CH, Jatoi, Aminah A, Vigano, Antonio, Putman, Ted, Kezhuo, Zhang, Sladek, Robert, Enjiu, LM, Gomes, SP, Matos-Neto, E, Rossi-Fanneli, F, Seelaender, MC, Ebadi, Maryam, Mazurak, Vera C, Bhatia, Nikita, Padliya, Neerav D, Stadler, Volker, Dariani, Maghsoud, Hariri, Robert J, Parker, Valorie A, Matthews, Ryan R, Bonetto, Andrea, Puppa, Melissa, Kang, Kyung Shin, Mohammed, Khalid S, Robling, Alexander G, Toledo, Míriam, Oliva, Francesc, Luque, Melania, Betancourt, Angelica, Marmonti, Enrica, López-Soriano, Francisco J, Busquets, Sílvia, Theal, Rebecca, Jiang, Heng, Sanchez, Anthony, Hussain, Sabah N, Serpe, R, Madeddu, C, Gudiño, V, Gabba, S, Antoni, G, Macciò, A, and Banni, S
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Abstracts - Published
- 2015
41. Relationship of peak exercise capacity with indexes of peripheral muscle vasodilation
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KOSMAS, EPAMINONDAS N., HUSSAIN, SABAH N. A., MONTSERRAT, JOSEP M., and LEVY, ROBERT D.
- Published
- 1996
42. Protective role of Parkin in skeletal muscle contractile and mitochondrial function
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Gouspillou, Gilles, primary, Godin, Richard, additional, Piquereau, Jérome, additional, Picard, Martin, additional, Mofarrahi, Mahroo, additional, Mathew, Jasmin, additional, Purves-Smith, Fennigje M., additional, Sgarioto, Nicolas, additional, Hepple, Russell T., additional, Burelle, Yan, additional, and Hussain, Sabah N. A., additional
- Published
- 2018
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43. Observation of B+ -> J/psi 3 pi(+)2 pi(-) and B+ -> psi (2S)pi(+)pi(+)pi(-) decays
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Aaij, R., Adeva, B., Adinolfi, M., Ajaltouni, Z., Akar, S., Albrecht, J., Alessio, F., Alexander, M. H., Ali, S., Alkhazov, G., Cartelle, P. Alvarez, Alves, A. A. Jr, Amato, S., Amerio, S., Amhis, Y., BEACH, LA, Anderlini, L., Andreassi, G., Andreotti, M., Andrews, J.E., Appleby, R.B., Archilli, F., d'Argent, P., Romeu, J. Arnau, Artamonov, AY, Artuso, M., Aslanides, E., Auriemma, G., Baalouch, M., Babuschkin, I., Bachmann, S, Back, Jaap Willem, Badalov, A., Baesso, C., Baker, S, Baldini, W., Barlow, R.J., Barschel, C., Barsuk, S., Barter, W., Baszczyk, M., Batozskaya, V., Batsukh, B., Battista, V., Bay, A., Beaucourt, L., Beddow, J., Bedeschi, F., Bediaga, I., Bel, L. J., Bellee, V., Belloli, N., Belous, K., Belyaev, I., Ben-Haim, E., Bencivenni, G., Benson, S, Benton, J., Berezhnoy, A., Bernet, R., Bertolin, A., Castano-Betancourt, Martha, Betti, F., Bettler, M.O., van Beuzekom, MG, Bezshyiko, Ia, Bifani, S., Billoir, P., Bird, T., Birnkraut, A., Bitadze, A., Bizzeti, A., Blake, T., Blanc, F., Blouw, J., Blusk, S., Bocci, V., Boettcher, Thomas, Bondar, A., Bondar, N., Bonivento, W., Bordyuzhin, I., Borgheresi, A., Borghi, S., Borisyak, M., Borsato, M., Bossu, F., Boubdir, M., Bowcock, T. J. V., Bowen, D.E., Bozzi, C., Braun, S., Britsch, M., Britton, T., Brodzicka, J., Buchanan, E., Burr, C., Bursche, A., Buytaert, R. J., Cadeddu, S., Calabrese, J. R., Calvi, M., Gomez, M. Calvo, Camboni, A., Campana, P., Perez, D. H. Campora, Capriotti, L., Carbone, A., Carboni, G., Cardinale, R., Cardini, A., Carniti, P., Carson, L., Akiba, K. Carvalho, Casse, G., Cassina, L., Garcia, L. 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K., Kurek, K., Kvaratskheliya, T., Lacarrere, D., Lafferty, G., Lai, A., Lanfranchi, G., Langenbruch, C., Latham, T., Lazzeroni, C., Le Gac, R., Van Leerdam, J., Lees, J. -P., Leflat, A., Lefrancois, J., Lefevre, R., Lemaitre, F., Cid, E. Lemos, Leroy, O., Lesiak, T., Leverington, B., Li, Y, Likhomanenko, T., Lindner, R., Linn, C., Lionetto, F., Liu, B., Liu, X., Loh, D., Longstaff, I., Lopes, J. H., Lucchesi, D., Lucio Martinez, M., Luo, Haibin, Lupato, A., Luppi, E., Lupton, O., Lusiani, A., Lyu, X. R., Machefert, F., Maciuc, F., Maev, O., Maguire, Kate, Malde, S., Malinin, A., Maltsev, T., Manca, G., Mancinelli, G., Manning, P., Maratas, J., Marchand, J. F., Marconi, U., Benito, C. Marin, Marino, Paolo, Marks, J. D., Martellotti, G., Martin, M., Martinelli, M., Santos, D. Martinez, Vidal, F. Martinez, Tostes, D. Martins, Massacrier, L. M., Massafferri, A., Matev, R., Mathad, A., Mathe, Z., Matteuzzi, C., Mauri, A., Maurin, B., Mazurov, A., McCann, Linda M., McCarthy, Patrick J., McNab, A., McNulty, R., Meadows, B., Meier, F., Meissner, M., Melnychuk, D., Merk, M., Merli, A., Michielin, E., Milanes, D. A., Minard, M. -N., Mitzel, D. S., Mogini, A., Rodriguez, J. Molina, Moreno-Monroy, Ana I., Monteil, S., Morandin, M., Morawski, P., Morda, A., Morello, M. J., Moron, J., Morris, A. -B., Mountain, R., Muheim, F., Mulder, M, Mussini, M., Muller, D., Muller, J., Muller, K, Muller, V, Naik, P., Nakada, T., Nandakumar, R., Nandi, A., Nasteva, I., Needham, M., Neri, N., Neubert, S., Neufeld, N., Neuner, M., Nguyen, A. D., Nguyen, T. D., Nguyen-Mau, C., Nieswand, S., Niet, R., Nikitin, N., Nikodem, T., Novoselov, A., O'Hanlon, D. P., Oblakowska-Mucha, A., Obraztsov, V., Ogilvy, S., Oldeman, R., Onderwater, C. J. G., Goicochea, J. M. Otalora, Otto, A., Owen, Randall P., Oyanguren, A., Pais, P. 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K., Kurek, K., Kvaratskheliya, T., Lacarrere, D., Lafferty, G., Lai, A., Lanfranchi, G., Langenbruch, C., Latham, T., Lazzeroni, C., Le Gac, R., Van Leerdam, J., Lees, J. -P., Leflat, A., Lefrancois, J., Lefevre, R., Lemaitre, F., Cid, E. Lemos, Leroy, O., Lesiak, T., Leverington, B., Li, Y, Likhomanenko, T., Lindner, R., Linn, C., Lionetto, F., Liu, B., Liu, X., Loh, D., Longstaff, I., Lopes, J. H., Lucchesi, D., Lucio Martinez, M., Luo, Haibin, Lupato, A., Luppi, E., Lupton, O., Lusiani, A., Lyu, X. R., Machefert, F., Maciuc, F., Maev, O., Maguire, Kate, Malde, S., Malinin, A., Maltsev, T., Manca, G., Mancinelli, G., Manning, P., Maratas, J., Marchand, J. F., Marconi, U., Benito, C. Marin, Marino, Paolo, Marks, J. D., Martellotti, G., Martin, M., Martinelli, M., Santos, D. Martinez, Vidal, F. Martinez, Tostes, D. Martins, Massacrier, L. M., Massafferri, A., Matev, R., Mathad, A., Mathe, Z., Matteuzzi, C., Mauri, A., Maurin, B., Mazurov, A., McCann, Linda M., McCarthy, Patrick J., McNab, A., McNulty, R., Meadows, B., Meier, F., Meissner, M., Melnychuk, D., Merk, M., Merli, A., Michielin, E., Milanes, D. A., Minard, M. -N., Mitzel, D. S., Mogini, A., Rodriguez, J. Molina, Moreno-Monroy, Ana I., Monteil, S., Morandin, M., Morawski, P., Morda, A., Morello, M. J., Moron, J., Morris, A. -B., Mountain, R., Muheim, F., Mulder, M, Mussini, M., Muller, D., Muller, J., Muller, K, Muller, V, Naik, P., Nakada, T., Nandakumar, R., Nandi, A., Nasteva, I., Needham, M., Neri, N., Neubert, S., Neufeld, N., Neuner, M., Nguyen, A. D., Nguyen, T. D., Nguyen-Mau, C., Nieswand, S., Niet, R., Nikitin, N., Nikodem, T., Novoselov, A., O'Hanlon, D. P., Oblakowska-Mucha, A., Obraztsov, V., Ogilvy, S., Oldeman, R., Onderwater, C. J. G., Goicochea, J. M. Otalora, Otto, A., Owen, Randall P., Oyanguren, A., Pais, P. 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- Abstract
The decays B+-> J/psi 3 pi(+)2 pi(-) and B+ -> psi(2S)pi(+)pi(+)pi(-) are observed for the first time using a data sample corresponding to an integrated luminosity of 3.0 fb(-1), collected by the LHCb experiment in proton- proton collisions at the centre-of-mass energies of 7 and 8 TeV. The branching fractions relative to that of B+ -> psi(2S)K+ are measured to beB(B+-> J/psi 3 pi(+)2 pi(-))/B(B+ -> psi (2S)K+) = (1.88 +/- 0.17 +/- 0.09)x10(-2).B(B+ -> psi(2S)pi(+)pi(+)pi(-))/B(B+ -> psi (2S)K+) = (3.04 +/- 0.50 +/- 0.26)X10(-2)where the first uncertainties are statistical and the second are systematic.
- Published
- 2017
44. Mechanisms of Chronic Muscle Wasting and Dysfunction after an Intensive Care Unit Stay
- Author
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dos Santos, Claudia, Hussain, Sabah N. A., Mathur, Sunita, Picard, Martin, Herridge, Margaret, Correa, Judy, Bain, Alexandra, Guo, Yeting, Advani, Andrew, Advani, Suzanne L., Tomlinson, George, Katzberg, Hans, Streutker, Catherine J., Cameron, Jill I., Schols, Annemie, Gosker, Harry R., Batt, Jane, Pulmonologie, and RS: NUTRIM - R3 - Chronic inflammatory disease and wasting
- Subjects
muscle atrophy ,mitochondria ,autophagy ,satellite cell ,ubiquitin-proteasome system - Abstract
Rationale: Critical illness survivors often experience permanent functional disability due to intensive care unit (ICU)-acquired weakness. The mechanisms responsible for long-term weakness persistence versus resolution are unknown. Objectives: To delineate cellular mechanisms underlying long-term weakness persistence in ICU survivors. Methods: We conducted a nested, prospective study of critically ill patients mechanically ventilated for 7 days or longer. The patients were recruited from the RECOVER program and serially assessed over 6 months after ICU discharge. Twenty-seven of 82 patients consented to participate; 15 and 11 patients were assessed at 7 days and 6 months after ICU discharge, respectively. Measurements and Main Results: We assessed motor functional capacity, quadriceps size, strength, and voluntary contractile capacity and performed electromyography, nerve conduction studies, and vastus lateralis biopsies for histologic, cellular, and molecular analyses. Strength and quadriceps cross-sectional areas were decreased 7 days after ICU discharge. Weakness persisted to 6 months and correlated with decreased function. Quadriceps atrophy resolved in 27% patients at 6 months. Muscle mass reconstitution did not correlate with resolution of weakness, owing to persistent impaired voluntary contractile capacity. Compared with Day 7, increased ubiquitin proteasome system mediated muscle proteolysis, inflammation, and decreased mitochondrial content all normalized at 6 months. Autophagy markers were normal at 6 months. Patients with sustained atrophy had decreased muscle progenitor (satellite) cell content. Conclusions: Long-term weakness in ICU survivors results from heterogeneous muscle pathophysiology with variable combinations of muscle atrophy and impaired contractile capacity. These findings are not explained by ongoing muscle proteolysis, inflammation, or diminished mitochondrial content. Sustained muscle atrophy is associated with decreased satellite cell content and compromised muscle regrowth, suggesting impaired regenerative capacity.
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- 2016
45. Regulation of ULK1 Expression and Autophagy by STAT1
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Goldberg, Alexander A., primary, Nkengfac, Bernard, additional, Sanchez, Anthony M.J., additional, Moroz, Nikolay, additional, Qureshi, Salman T., additional, Koromilas, Antonis E., additional, Wang, Shuo, additional, Burelle, Yan, additional, Hussain, Sabah N., additional, and Kristof, Arnold S., additional
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- 2017
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46. PulmonaryPseudomonas aeruginosainfection induces autophagy and proteasome proteolytic pathways in skeletal muscles: effects of a pressurized whey protein-based diet in mice
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Kishta, Osama A., primary, Guo, Yeting, additional, Mofarrahi, Mahroo, additional, Stana, Flavia, additional, Lands, Larry C., additional, and Hussain, Sabah N. A., additional
- Published
- 2017
- Full Text
- View/download PDF
47. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
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W., Johnson, James D., Jonasch, Eric, Jones, Chris, Joosten, Leo A. B., Jordan, Joaquin, Joseph, Anna-Maria, Joseph, Bertrand, Joubert, Annie M., Ju, Dianwen, Ju, Jingfang, Juan, Hsueh-Fen, Juenemann, Katrin, Juhasz, Gabor, Jung, Hye Seung, Jung, Jae U., Jung, Yong-Keun, Jungbluth, Heinz, Justice, Matthew J., Jutten, Barry, Kaakoush, Nadeem O., Kaarniranta, Kai, Kaasik, Allen, Kabuta, Tomohiro, Kaeffer, Bertrand, Kagedal, Katarina, Kahana, Alon, Kajimura, Shingo, Kakhlon, Or, Kalia, Manjula, Kalvakolanu, Dhan V., Kamada, Yoshiaki, Kambas, Konstantinos, Kaminskyy, Vitaliy O., Kampinga, Harm H., Kandouz, Mustapha, Kang, Chanhee, Kang, Rui, Kang, Tae-Cheon, Kanki, Tomotake, Kanneganti, Thirumala-Devi, Kanno, Haruo, Kanthasamy, Anumantha G., Kantorow, Marc, Kaparakis-Liaskos, Maria, Kapuy, Orsolya, Karantza, Vassiliki, Karim, Md Razaul, Karmakar, Parimal, Kaser, Arthur, Kaushik, Susmita, Kawula, Thomas, Kaynar, A. 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Sue, Menna-Barreto, Rubem F. S., Menon, Manoj B., Meraz-Rios, Marco A., Merla, Giuseppe, Merlini, Luciano, Merlot, Angelica M., Meryk, Andreas, Meschini, Stefania, Meyer, Joel N., Mi, Man-Tian, Miao, Chao-Yu, Micale, Lucia, Michaeli, Simon, Michiels, Carine, Migliaccio, Anna Rita, Mihailidou, Anastasia Susie, Mijaljica, Dalibor, Mikoshiba, Katsuhiko, Milan, Enrico, Miller-Fleming, Leonor, Mills, Gordon B., Mills, Ian G., Minakaki, Georgia, Minassian, Berge A., Ming, Xiu-Fen, Minibayeva, Farida, Minina, Elena A., Mintern, Justine D., Minucci, Saverio, Miranda-Vizuete, Antonio, Mitchell, Claire H., Miyamoto, Shigeki, Miyazawa, Keisuke, Mizushima, Noboru, Mnich, Katarzyna, Mograbi, Baharia, Mohseni, Simin, Moita, Luis Ferreira, Molinari, Marco, Molinari, Maurizio, Moller, Andreas Buch, Mollereau, Bertrand, Mollinedo, Faustino, Monick, Martha M., Montagnaro, Serena, Montell, Craig, Moore, Darren J., Moore, Michael N., Mora-Rodriguez, Rodrigo, Moreira, Paula I., Morel, Etienne, Morelli, Maria Beatrice, Moreno, Sandra, Morgan, Michael J., Moris, Arnaud, Moriyasu, Yuji, Morrison, Janna L., Morrison, Lynda A., Morselli, Eugenia, Moscat, Jorge, Moseley, Pope L., Mostowy, Serge, Motori, Elisa, Mottet, Denis, Mottram, Jeremy C., Moussa, Charbel E-H, Mpakou, Vassiliki E., Mukhtar, Hasan, Levy, Jean M. 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O., Noda, Takeshi, Noegel, Angelika A., Nolte, Elsie Magdalena, Norberg, Erik, Norga, Koenraad K., Noureini, Sakineh Kazemi, Notomi, Shoji, Notterpek, Lucia, Nowikovsky, Karin, Nukina, Nobuyuki, Nuernberger, Thorsten, O'Donnell, Valerie B., O'Donovan, Tracey, O'Dwyer, Peter J., Oehme, Ina, Oeste, Clara L., Ogawa, Michinaga, Ogretmen, Besim, Ogura, Yuji, Oh, Young J., Ohmuraya, Masaki, Ohshima, Takayuki, Ojha, Rani, Okamoto, Koji, Okazaki, Toshiro, Oliver, F. Javier, Ollinger, Karin, Olsson, Stefan, Orban, Daniel P., Ordonez, Paulina, Orhon, Idil, Orosz, Laszlo, O'Rourke, Eyleen J., Orozco, Helena, Ortega, Angel L., Ortona, Elena, Osellame, Laura D., Oshima, Junko, Oshima, Shigeru, Osiewacz, Heinz D., Otomo, Takanobu, Otsu, Kinya, Ou, Jing-hsiung James, Outeiro, Tiago F., Ouyang, Dong-yun, Ouyang, Hongjiao, Overholtzer, Michael, Ozbun, Michelle A., Ozdinler, P. 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S., Patschan, Daniel, Patterson, Cam, Pattingre, Sophie, Pattison, Scott, Pause, Arnim, Pavenstaedt, Hermann, Pavone, Flaminia, Pedrozo, Zully, Pena, Fernando J., Penalva, Miguel A., Pende, Mario, Peng, Jianxin, Penna, Fabio, Penninger, Josef M., Pensalfini, Anna, Pepe, Salvatore, Pereira, Gustavo J. S., Pereira, Paulo C., Perez-de la Cruz, Veronica, Esther Perez-Perez, Maria, Perez-Rodriguez, Diego, Perez-Sala, Dolores, Perier, Celine, Perl, Andras, Perlmutter, David H., Perrotta, Ida, Pervaiz, Shazib, Pesonen, Maija, Pessin, Jeffrey E., Peters, Godefridus J., Petersen, Morten, Petrache, Irina, Petrof, Basil J., Petrovski, Goran, Phang, James M., Piacentini, Mauro, Pierdominici, Marina, Pierre, Philippe, Pierrefite-Carle, Valerie, Pietrocola, Federico, Pimentel-Muinos, Felipe X., Pinar, Mario, Pineda, Benjamin, Pinkas-Kramarski, Ronit, Pinti, Marcello, Pinton, Paolo, Piperdi, Bilal, Piret, James M., Platanias, Leonidas C., Platta, Harald W., Plowey, Edward D., Poggeler, Stefanie, Poirot, Marc, Polcic, Peter, Poletti, Angelo, Poon, Audrey H., Popelka, Hana, Popova, Blagovesta, Poprawa, Izabela, Poulose, Shibu M., Poulton, Joanna, Powers, Scott K., Powers, Ted, Pozuelo-Rubio, Mercedes, Prak, Krisna, Prange, Reinhild, Prescott, Mark, Priault, Muriel, Prince, Sharon, Proia, Richard L., Proikas-Cezanne, Tassula, Prokisch, Holger, Promponas, Vasilis J., Przyklenk, Karin, Puertollano, Rosa, Pugazhenthi, Subbiah, Puglielli, Luigi, Pujol, Aurora, Puyal, Julien, Pyeon, Dohun, Qi, Xin, Qian, Wen-bin, Qin, Zheng-Hong, Qiu, Yu, Qu, Ziwei, Quadrilatero, Joe, Quinn, Frederick, Raben, Nina, Rabinowich, Hannah, Radogna, Flavia, Ragusa, Michael J., Rahmani, Mohamed, Raina, Komal, Ramanadham, Sasanka, Ramesh, Rajagopal, Rami, Abdelhaq, Randall-Demllo, Sarron, Randow, Felix, Rao, Hai, Rao, V. 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Mark, Coppens, Isabelle, Corasaniti, Maria Tiziana, Corazzari, Marco, Corbalan, Ramon, Corcelle-Termeau, Elisabeth, Cordero, Mario D., Corral-Ramos, Cristina, Corti, Olga, Cossarizza, Andrea, Costelli, Paola, Costes, Safia, Coto-Montes, Ana, Cottet, Sandra, Couve, Eduardo, Covey, Lori R., Cowart, L. 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Y., De Milito, Angelo, De Santi, Mauro, de Souza, Wanderley, De Tata, Vincenzo, De Zio, Daniela, Debnath, Jayanta, Dechant, Reinhard, Decuypere, Jean-Paul, Deegan, Shane, Dehay, Benjamin, Del Bello, Barbara, Del Re, Dominic P., Delage-Mourroux, Regis, Delbridge, Lea M. D., Deldicque, Louise, Delorme-Axford, Elizabeth, Deng, Yizhen, Dengjel, Joern, Denizot, Melanie, Dent, Paul, Der, Channing J., Deretic, Vojo, Derrien, Benoit, Deutsch, Eric, Devarenne, Timothy P., Devenish, Rodney J., Di Bartolomeo, Sabrina, Di Daniele, Nicola, Di Domenico, Fabio, Di Nardo, Alessia, Di Paola, Simone, Di Pietro, Antonio, Di Renzo, Livia, DiAntonio, Aaron, Diaz-Araya, Guillermo, Diaz-Laviada, Ines, Diaz-Meco, Maria T., Diaz-Nido, Javier, Dickey, Chad A., Dickson, Robert C., Diederich, Marc, Digard, Paul, Dikic, Ivan, Dinesh-Kumar, Savithrama P., Ding, Chan, Ding, Wen-Xing, Ding, Zufeng, Dini, Luciana, Distler, Joerg H. W., Diwan, Abhinav, Djavaheri-Mergny, Mojgan, Dmytruk, Kostyantyn, Dobson, Renwick C. J., Doetsch, Volker, Dokladny, Karol, Dokudovskaya, Svetlana, Donadelli, Massimo, Dong, X. Charlie, Dong, Xiaonan, Dong, Zheng, Donohue, Terrence M., Jr., Doran, Kelly S., D'Orazi, Gabriella, Dorn, Gerald W., II, Dosenko, Victor, Dridi, Sami, Drucker, Liat, Du, Jie, Du, Li-Lin, Du, Lihuan, du Toit, Andre, Dua, Priyamvada, Duan, Lei, Duann, Pu, Dubey, Vikash Kumar, Duchen, Michael R., Duchosal, Michel A., Duez, Helene, Dugail, Isabelle, Dumit, Veronica I., Duncan, Mara C., Dunlop, Elaine A., Dunn, William A., Jr., Dupont, Nicolas, Dupuis, Luc, Duran, Raul V., Durcan, Thomas M., Duvezin-Caubet, Stephane, Duvvuri, Umamaheswar, Eapen, Vinay, Ebrahimi-Fakhari, Darius, Echard, Arnaud, Eckhart, Leopold, Edelstein, Charles L., Edinger, Aimee L., Eichinger, Ludwig, Eisenberg, Tobias, Eisenberg-Lerner, Avital, Eissa, N. Tony, El-Deiry, Wafik S., El-Khoury, Victoria, Elazar, Zvulun, Eldar-Finkelman, Hagit, Elliott, Chris J. H., Emanuele, Enzo, Emmenegger, Urban, Engedal, Nikolai, Engelbrecht, Anna-Mart, Engelender, Simone, Enserink, Jorrit M., Erdmann, Ralf, Erenpreisa, Jekaterina, Eri, Rajaraman, Eriksen, Jason L., Erman, Andreja, Escalante, Ricardo, Eskelinen, Eeva-Liisa, Espert, Lucile, Esteban-Martinez, Lorena, Evans, Thomas J., Fabri, Mario, Fabrias, Gemma, Fabrizi, Cinzia, Facchiano, Antonio, Faergeman, Nils J., Faggioni, Alberto, Fairlie, W. Douglas, Fan, Chunhai, Fan, Daping, Fan, Jie, Fang, Shengyun, Fanto, Manolis, Fanzani, Alessandro, Farkas, Thomas, Faure, Mathias, Favier, Francois B., Fearnhead, Howard, Federici, Massimo, Fei, Erkang, Felizardo, Tania C., Feng, Hua, Feng, Yibin, Feng, Yuchen, Ferguson, Thomas A., Fernandez, Alvaro F., Fernandez-Barrena, Maite G., Fernandez-Checa, Jose C., Fernandez-Lopez, Arsenio, Fernandez-Zapico, Martin E., Feron, Olivier, Ferraro, Elisabetta, Ferreira-Halder, Carmen Verissima, Fesus, Laszlo, Feuer, Ralph, Fiesel, Fabienne C., Filippi-Chiela, Eduardo C., Filomeni, Giuseppe, Fimia, Gian Maria, Fingert, John H., Finkbeiner, Steven, Finkel, Toren, Fiorito, Filomena, Fisher, Paul B., Flajolet, Marc, Flamigni, Flavio, Florey, Oliver, Florio, Salvatore, Floto, R. Andres, Folini, Marco, Follo, Carlo, Fon, Edward A., Fornai, Francesco, Fortunato, Franco, Fraldi, Alessandro, Franco, Rodrigo, Francois, Arnaud, Francois, Aurelie, Frankel, Lisa B., Fraser, Iain D. C., Frey, Norbert, Freyssenet, Damien G., Frezza, Christian, Friedman, Scott L., Frigo, Daniel E., Fu, Dongxu, Fuentes, Jose M., Fueyo, Juan, Fujitani, Yoshio, Fujiwara, Yuuki, Fujiya, Mikihiro, Fukuda, Mitsunori, Fulda, Simone, Fusco, Carmela, Gabryel, Bozena, Gaestel, Matthias, Gailly, Philippe, Gajewska, Malgorzata, Galadari, Sehamuddin, Galili, Gad, Galindo, Inmaculada, Galindo, Maria F., Galliciotti, Giovanna, Galluzzi, Lorenzo, Galluzzi, Luca, Galy, Vincent, Gammoh, Noor, Gandy, Sam, Ganesan, Anand K., Ganesan, Swamynathan, Ganley, Ian G., Gannage, Monique, Gao, Fen-Biao, Gao, Feng, Gao, Jian-Xin, Garcia Nannig, Lorena, Vescovi, Eleonora Garcia, Garcia-Macia, Marina, Garcia-Ruiz, Carmen, Garg, Abhishek D., Garg, Pramod Kumar, Gargini, Ricardo, Gassen, Nils Christian, Gatica, Damian, Gatti, Evelina, Gavard, Julie, Gavathiotis, Evripidis, Ge, Liang, Ge, Pengfei, Ge, Shengfang, Gean, Po-Wu, Gelmetti, Vania, Genazzani, Armando A., Geng, Jiefei, Genschik, Pascal, Gerner, Lisa, Gestwicki, Jason E., Gewirtz, David A., Ghavami, Saeid, Ghigo, Eric, Ghosh, Debabrata, Giammarioli, Anna Maria, Giampieri, Francesca, Giampietri, Claudia, Giatromanolaki, Alexandra, Gibbings, Derrick J., Gibellini, Lara, Gibson, Spencer B., Ginet, Vanessa, Giordano, Antonio, Giorgini, Flaviano, Giovannetti, Elisa, Girardin, Stephen E., Gispert, Suzana, Giuliano, Sandy, Gladson, Candece L., Glavic, Alvaro, Gleave, Martin, Godefroy, Nelly, Gogal, Robert M., Jr., Gokulan, Kuppan, Goldman, Gustavo H., Goletti, Delia, Goligorsky, Michael S., Gomes, Aldrin V., Gomes, Ligia C., Gomez, Hernando, Gomez-Manzano, Candelaria, Gomez-Sanchez, Ruben, Goncalves, Dawit A. P., Goncu, Ebru, Gong, Qingqiu, Gongora, Celine, Gonzalez, Carlos B., Gonzalez-Alegre, Pedro, Gonzalez-Cabo, Pilar, Ana Gonzalez-Polo, Rosa, Goping, Ing Swie, Gorbea, Carlos, Gorbunov, Nikolai V., Goring, Daphne R., Gorman, Adrienne M., Gorski, Sharon M., Goruppi, Sandro, Goto-Yamada, Shino, Gotor, Cecilia, Gottlieb, Roberta A., Gozes, Illana, Gozuacik, Devrim, Graba, Yacine, Graef, Martin, Granato, Giovanna E., Grant, Gary Dean, Grant, Steven, Gravina, Giovanni Luca, Green, Douglas R., Greenhough, Alexander, Greenwood, Michael T., Grimaldi, Benedetto, Gros, Frederic, Grose, Charles, Groulx, Jean-Francois, Gruber, Florian, Grumati, Paolo, Grune, Tilman, Guan, Jun-Lin, Guan, Kun-Liang, Guerra, Barbara, Guillen, Carlos, Gulshan, Kailash, Gunst, Jan, Guo, Chuanyong, Guo, Lei, Guo, Ming, Guo, Wenjie, Guo, Xu-Guang, Gust, Andrea A., Gustafsson, Asa B., Gutierrez, Elaine, Gutierrez, Maximiliano G., Gwak, Ho-Shin, Haas, Albert, Haber, James E., Hadano, Shinji, Hagedorn, Monica, Hahn, David R., Halayko, Andrew J., Hamacher-Brady, Anne, Hamada, Kozo, Hamai, Ahmed, Hamann, Andrea, Hamasaki, Maho, Hamer, Isabelle, Hamid, Qutayba, Hammond, Ester M., Han, Feng, Han, Weidong, Handa, James T., Hanover, John A., Hansen, Malene, Harada, Masaru, Harhaji-Trajkovic, Ljubica, Harper, J. Wade, Harrath, Abdel Halim, Harris, Adrian L., Harris, James, Hasler, Udo, Hasselblatt, Peter, Hasui, Kazuhisa, Hawley, Robert G., Hawley, Teresa S., He, Congcong, He, Cynthia Y., He, Fengtian, He, Gu, He, Rong-Rong, He, Xian-Hui, He, You-Wen, He, Yu-Ying, Heath, Joan K., Hebert, Marie-Josee, Heinzen, Robert A., Helgason, Gudmundur Vignir, Hensel, Michael, Henske, Elizabeth P., Her, Chengtao, Herman, Paul K., Hernandez, Agustin, Hernandez, Carlos, Hernandez-Tiedra, Sonia, Hetz, Claudio, Hiesinger, P. Robin, Higaki, Katsumi, Hilfiker, Sabine, Hill, Bradford G., Hill, Joseph A., Hill, William D., Hino, Keisuke, Hofius, Daniel, Hofman, Paul, Hoeglinger, Guenter U., Hoehfeld, Joerg, Holz, Marina K., Hong, Yonggeun, Hood, David A., Hoozemans, Jeroen J. M., Hoppe, Thorsten, Hsu, Chin, Hsu, Chin-Yuan, Hsu, Li-Chung, Hu, Dong, Hu, Guochang, Hu, Hong-Ming, Hu, Hongbo, Hu, Ming Chang, Hu, Yu-Chen, Hu, Zhuo-Wei, Hua, Fang, Hua, Ya, Huang, Canhua, Huang, Huey-Lan, Huang, Kuo-How, Huang, Kuo-Yang, Huang, Shile, Huang, Shiqian, Huang, Wei-Pang, Huang, Yi-Ran, Huang, Yong, Huang, Yunfei, Huber, Tobias B., Huebbe, Patricia, Huh, Won-Ki, Hulmi, Juha J., Hur, Gang Min, Hurley, James H., Husak, Zvenyslava, Hussain, Sabah N. A., Hussain, Salik, Hwang, Jung Jin, Hwang, Seungmin, Hwang, Thomas I. S., Ichihara, Atsuhiro, Imai, Yuzuru, Imbriano, Carol, Inomata, Megumi, Into, Takeshi, Iovane, Valentina, Iovanna, Juan L., Iozzo, Renato V., Ip, Nancy Y., Irazoqui, Javier E., Iribarren, Pablo, Isaka, Yoshitaka, Isakovic, Aleksandra J., Ischiropoulos, Harry, Isenberg, Jeffrey S., Ishaq, Mohammad, Ishida, Hiroyuki, Ishii, Isao, Ishmael, Jane E., Isidoro, Ciro, Isobe, Ken-ichi, Isono, Erika, Issazadeh-Navikas, Shohreh, Itahana, Koji, Itakura, Eisuke, Ivanov, Andrei I., Iyer, Anand Krishnan V., Izquierdo, Jose M., Izumi, Yotaro, Izzo, Valentina, Jaeaettelae, Marja, Jaber, Nadia, Jackson, Daniel John, Jackson, William T., Jacob, Tony George, Jacques, Thomas S., Jagannath, Chinnaswamy, Jain, Ashish, Jana, Nihar Ranjan, Jang, Byoung Kuk, Jani, Alkesh, Janji, Bassam, Jannig, Paulo Roberto, Jansson, Patric J., Jean, Steve, Jendrach, Marina, Jeon, Ju-Hong, Jessen, Niels, Jeung, Eui-Bae, Jia, Kailiang, Jia, Lijun, Jiang, Hong, Jiang, Hongchi, Jiang, Liwen, Jiang, Teng, Jiang, Xiaoyan, Jiang, Xuejun, Jiang, Ying, Jiang, Yongjun, Jimenez, Alberto, Jin, Cheng, Jin, Hongchuan, Jin, Lei, Jin, Meiyan, Jin, Shengkan, Jinwal, Umesh Kumar, Jo, Eun-Kyeong, Johansen, Terje, Johnson, Daniel E., Johnson, Gail V. W., Johnson, James D., Jonasch, Eric, Jones, Chris, Joosten, Leo A. B., Jordan, Joaquin, Joseph, Anna-Maria, Joseph, Bertrand, Joubert, Annie M., Ju, Dianwen, Ju, Jingfang, Juan, Hsueh-Fen, Juenemann, Katrin, Juhasz, Gabor, Jung, Hye Seung, Jung, Jae U., Jung, Yong-Keun, Jungbluth, Heinz, Justice, Matthew J., Jutten, Barry, Kaakoush, Nadeem O., Kaarniranta, Kai, Kaasik, Allen, Kabuta, Tomohiro, Kaeffer, Bertrand, Kagedal, Katarina, Kahana, Alon, Kajimura, Shingo, Kakhlon, Or, Kalia, Manjula, Kalvakolanu, Dhan V., Kamada, Yoshiaki, Kambas, Konstantinos, Kaminskyy, Vitaliy O., Kampinga, Harm H., Kandouz, Mustapha, Kang, Chanhee, Kang, Rui, Kang, Tae-Cheon, Kanki, Tomotake, Kanneganti, Thirumala-Devi, Kanno, Haruo, Kanthasamy, Anumantha G., Kantorow, Marc, Kaparakis-Liaskos, Maria, Kapuy, Orsolya, Karantza, Vassiliki, Karim, Md Razaul, Karmakar, Parimal, Kaser, Arthur, Kaushik, Susmita, Kawula, Thomas, Kaynar, A. Murat, Ke, Po-Yuan, Ke, Zun-Ji, Kehrl, John H., Keller, Kate E., Kemper, Jongsook Kim, Kenworthy, Anne K., Kepp, Oliver, Kern, Andreas, Kesari, Santosh, Kessel, David, Ketteler, Robin, Kettelhut, Isis do Carmo, Khambu, Bilon, Khan, Muzamil Majid, Khandelwal, Vinoth K. M., Khare, Sangeeta, Kiang, Juliann G., Kiger, Amy A., Kihara, Akio, Kim, Arianna L., Kim, Cheol Hyeon, Kim, Deok Ryong, Kim, Do-Hyung, Kim, Eung Kweon, Kim, Hye Young, Kim, Hyung-Ryong, Kim, Jae-Sung, Kim, Jeong Hun, Kim, Jin Cheon, Kim, Jin Hyoung, Kim, Kwang Woon, Kim, Michael D., Kim, Moon-Moo, Kim, Peter K., Kim, Seong Who, Kim, Soo-Youl, Kim, Yong-Sun, Kim, Yonghyun, Kimchi, Adi, Kimmelman, Alec C., Kimura, Tomonori, King, Jason S., Kirkegaard, Karla, Kirkin, Vladimir, Kirshenbaum, Lorrie A., Kishi, Shuji, Kitajima, Yasuo, Kitamoto, Katsuhiko, Kitaoka, Yasushi, Kitazato, Kaio, Kley, Rudolf A., Klimecki, Walter T., Klinkenberg, Michael, Klucken, Jochen, Knaevelsrud, Helene, Knecht, Erwin, Knuppertz, Laura, Ko, Jiunn-Liang, Kobayashi, Satoru, Koch, Jan C., Koechlin-Ramonatxo, Christelle, Koenig, Ulrich, Ko, Young Ho, Koehler, Katja, Kohlwein, Sepp D., Koike, Masato, Komatsu, Masaaki, Kominami, Eiki, Kong, Dexin, Kong, Hee Jeong, Konstantakou, Eumorphia G., Kopp, Benjamin T., Korcsmaros, Tamas, Korhonen, Laura, Korolchuk, Viktor I., Koshkina, Nadya V., Kou, Yanjun, Koukourakis, Michael I., Koumenis, Constantinos, Kovacs, Attila L., Kovacs, Tibor, Kovacs, Werner J., Koya, Daisuke, Kraft, Claudine, Krainc, Dimitri, Kramer, Helmut, Kravic-Stevovic, Tamara, Krek, Wilhelm, Kretz-Remy, Carole, Krick, Roswitha, Krishnamurthy, Malathi, Kriston-Vizi, Janos, Kroemer, Guido, Kruer, Michael C., Kruger, Rejko, Ktistakis, Nicholas T., Kuchitsu, Kazuyuki, Kuhn, Christian, Kumar, Addanki Pratap, Kumar, Anuj, Kumar, Ashok, Kumar, Deepak, Kumar, Dhiraj, Kumar, Rakesh, Kumar, Sharad, Kundu, Mondira, Kung, Hsing-Jien, Kuno, Atsushi, Kuo, Sheng-Han, Kuret, Jeff, Kurz, Tino, Kwok, Terry, Kwon, Taeg Kyu, Kwon, Yong Tae, Kyrmizi, Irene, La Spada, Albert R., Lafont, Frank, Lahm, Tim, Lakkaraju, Aparna, Lam, Truong, Lamark, Trond, Lancel, Steve, Landowski, Terry H., Lane, Darius J. R., Lane, Jon D., Lanzi, Cinzia, Lapaquette, Pierre, Lapierre, Louis R., Laporte, Jocelyn, Laukkarinen, Johanna, Laurie, Gordon W., Lavandero, Sergio, Lavie, Lena, LaVoie, Matthew J., Law, Betty Yuen Kwan, Law, Helen Ka-wai, Law, Kelsey B., Layfield, Robert, Lazo, Pedro A., Le Cam, Laurent, Le Roch, Karine G., Le Stunff, Herve, Leardkamolkarn, Vijittra, Lecuit, Marc, Lee, Byung-Hoon, Lee, Che-Hsin, Lee, Erinna F., Lee, Gyun Min, Lee, He-Jin, Lee, Hsinyu, Lee, Jae Keun, Lee, Jongdae, Lee, Ju-Hyun, Lee, Jun Hee, Lee, Michael, Lee, Myung-Shik, Lee, Patty J., Lee, Sam W., Lee, Seung-Jae, Lee, Shiow-Ju, Lee, Stella Y., Lee, Sug Hyung, Lee, Sung Sik, Lee, Sung-Joon, Lee, Sunhee, Lee, Ying-Ray, Lee, Yong J., Lee, Young H., Leeuwenburgh, Christiaan, Lefort, Sylvain, Legouis, Renaud, Lei, Jinzhi, Lei, Qun-Ying, Leib, David A., Leibowitz, Gil, Lekli, Istvan, Lemaire, Stephane D., Lemasters, John J., Lemberg, Marius K., Lemoine, Antoinette, Leng, Shuilong, Lenz, Guido, Lenzi, Paola, Lerman, Lilach O., Barbato, Daniele Lettieri, Leu, Julia I-Ju, Leung, Hing Y., Levine, Beth, Lewis, Patrick A., Lezoualc'h, Frank, Li, Chi, Li, Faqiang, Li, Feng-Jun, Li, Jun, Li, Ke, Li, Lian, Li, Min, Li, Qiang, Li, Rui, Li, Sheng, Li, Wei, Li, Xiaotao, Li, Yumin, Lian, Jiqin, Liang, Chengyu, Liang, Qiangrong, Liao, Yulin, Liberal, Joana, Liberski, Pawel P., Lie, Pearl, Lieberman, Andrew P., Lim, Hyunjung Jade, Lim, Kah-Leong, Lim, Kyu, Lima, Raquel T., Lin, Chang-Shen, Lin, Chiou-Feng, Lin, Fang, Lin, Fangming, Lin, Fu-Cheng, Lin, Kui, Lin, Kwang-Huei, Lin, Pei-Hui, Lin, Tianwei, Lin, Wan-Wan, Lin, Yee-Shin, Lin, Yong, Linden, Rafael, Lindholm, Dan, Lindqvist, Lisa M., Lingor, Paul, Linkermann, Andreas, Liotta, Lance A., Lipinski, Marta M., Lira, Vitor A., Lisanti, Michael P., Liton, Paloma B., Liu, Bo, Liu, Chong, Liu, Chun-Feng, Liu, Fei, Liu, Hung-Jen, Liu, Jianxun, Liu, Jing-Jing, Liu, Jing-Lan, Liu, Ke, Liu, Leyuan, Liu, Liang, Liu, Quentin, Liu, Rong-Yu, Liu, Shiming, Liu, Shuwen, Liu, Wei, Liu, Xian-De, Liu, Xiangguo, Liu, Xiao-Hong, Liu, Xinfeng, Liu, Xu, Liu, Xueqin, Liu, Yang, Liu, Yule, Liu, Zexian, Liu, Zhe, Liuzzi, Juan P., Lizard, Gerard, Ljujic, Mila, Lodhi, Irfan J., Logue, Susan E., Lokeshwar, Bal L., Long, Yun Chau, Lonial, Sagar, Loos, Benjamin, Lopez-Otin, Carlos, Lopez-Vicario, Cristina, Lorente, Mar, Lorenzi, Philip L., Lorincz, Peter, Los, Marek, Lotze, Michael T., Lovat, Penny E., Lu, Binfeng, Lu, Bo, Lu, Jiahong, Lu, Qing, Lu, She-Min, Lu, Shuyan, Lu, Yingying, Luciano, Federic, Luckhart, Shirley, Lucocq, John Milton, Ludovico, Paula, Lugea, Aurelia, Lukacs, Nicholas W., Lum, Julian J., Lund, Anders H., Luo, Honglin, Luo, Jia, Luo, Shouqing, Luparello, Claudio, Lyons, Timothy, Ma, Jianjie, Ma, Yi, Ma, Yong, Ma, Zhenyi, Machado, Juliano, Machado-Santelli, Glaucia M., Macian, Fernando, MacIntosh, Gustavo C., MacKeigan, Jeffrey P., Macleod, Kay F., MacMicking, John D., MacMillan-Crow, Lee Ann, Madeo, Frank, Madesh, Muniswamy, Madrigal-Matute, Julio, Maeda, Akiko, Maeda, Tatsuya, Maegawa, Gustavo, Maellaro, Emilia, Maes, Hannelore, Magarinos, Marta, Maiese, Kenneth, Maiti, Tapas K., Maiuri, Luigi, Maiuri, Maria Chiara, Maki, Carl G., Malli, Roland, Malorni, Walter, Maloyan, Alina, Mami-Chouaib, Fathia, Man, Na, Mancias, Joseph D., Mandelkow, Eva-Maria, Mandell, Michael A., Manfredi, Angelo A., Manie, Serge N., Manzoni, Claudia, Mao, Kai, Mao, Zixu, Mao, Zong-Wan, Marambaud, Philippe, Marconi, Anna Maria, Marelja, Zvonimir, Marfe, Gabriella, Margeta, Marta, Margittai, Eva, Mari, Muriel, Mariani, Francesca V., Marin, Concepcio, Marinelli, Sara, Marino, Guillermo, Markovic, Ivanka, Marquez, Rebecca, Martelli, Alberto M., Martens, Sascha, Martin, Katie R., Martin, Seamus J., Martin, Shaun, Martin-Acebes, Miguel A., Martin-Sanz, Paloma, Martinand-Mari, Camille, Martinet, Wim, Martinez, Jennifer, Martinez-Lopez, Nuria, Martinez-Outschoorn, Ubaldo, Martinez-Velazquez, Moises, Martinez-Vicente, Marta, Martins, Waleska Kerllen, Mashima, Hirosato, Mastrianni, James A., Matarese, Giuseppe, Matarrese, Paola, Mateo, Roberto, Matoba, Satoaki, Matsumoto, Naomichi, Matsushita, Takehiko, Matsuura, Akira, Matsuzawa, Takeshi, Mattson, Mark P., Matus, Soledad, Maugeri, Norma, Mauvezin, Caroline, Mayer, Andreas, Maysinger, Dusica, Mazzolini, Guillermo D., McBrayer, Mary Kate, McCall, Kimberly, McCormick, Craig, McInerney, Gerald M., McIver, Skye C., McKenna, Sharon, McMahon, John J., McNeish, Iain A., Mechta-Grigoriou, Fatima, Medema, Jan Paul, Medina, Diego L., Megyeri, Klara, Mehrpour, Maryam, Mehta, Jawahar L., Mei, Yide, Meier, Ute-Christiane, Meijer, Alfred J., Melendez, Alicia, Melino, Gerry, Melino, Sonia, Tenorio de Melo, Edesio Jose, Mena, Maria A., Meneghini, Marc D., Menendez, Javier A., Menezes, Regina, Meng, Liesu, Meng, Ling-hua, Meng, Songshu, Menghini, Rossella, Menko, A. Sue, Menna-Barreto, Rubem F. S., Menon, Manoj B., Meraz-Rios, Marco A., Merla, Giuseppe, Merlini, Luciano, Merlot, Angelica M., Meryk, Andreas, Meschini, Stefania, Meyer, Joel N., Mi, Man-Tian, Miao, Chao-Yu, Micale, Lucia, Michaeli, Simon, Michiels, Carine, Migliaccio, Anna Rita, Mihailidou, Anastasia Susie, Mijaljica, Dalibor, Mikoshiba, Katsuhiko, Milan, Enrico, Miller-Fleming, Leonor, Mills, Gordon B., Mills, Ian G., Minakaki, Georgia, Minassian, Berge A., Ming, Xiu-Fen, Minibayeva, Farida, Minina, Elena A., Mintern, Justine D., Minucci, Saverio, Miranda-Vizuete, Antonio, Mitchell, Claire H., Miyamoto, Shigeki, Miyazawa, Keisuke, Mizushima, Noboru, Mnich, Katarzyna, Mograbi, Baharia, Mohseni, Simin, Moita, Luis Ferreira, Molinari, Marco, Molinari, Maurizio, Moller, Andreas Buch, Mollereau, Bertrand, Mollinedo, Faustino, Monick, Martha M., Montagnaro, Serena, Montell, Craig, Moore, Darren J., Moore, Michael N., Mora-Rodriguez, Rodrigo, Moreira, Paula I., Morel, Etienne, Morelli, Maria Beatrice, Moreno, Sandra, Morgan, Michael J., Moris, Arnaud, Moriyasu, Yuji, Morrison, Janna L., Morrison, Lynda A., Morselli, Eugenia, Moscat, Jorge, Moseley, Pope L., Mostowy, Serge, Motori, Elisa, Mottet, Denis, Mottram, Jeremy C., Moussa, Charbel E-H, Mpakou, Vassiliki E., Mukhtar, Hasan, Levy, Jean M. Mulcahy, Muller, Sylviane, Munoz-Moreno, Raquel, Munoz-Pinedo, Cristina, Muenz, Christian, Murphy, Maureen E., Murray, James T., Murthy, Aditya, Mysorekar, Indira U., Nabi, Ivan R., Nabissi, Massimo, Nader, Gustavo A., Nagahara, Yukitoshi, Nagai, Yoshitaka, Nagata, Kazuhiro, Nagelkerke, Anika, Nagy, Peter, Naidu, Samisubbu R., Nair, Sreejayan, Nakano, Hiroyasu, Nakatogawa, Hitoshi, Nanjundan, Meera, Napolitano, Gennaro, Naqvi, Naweed I., Nardacci, Roberta, Narendra, Derek P., Narita, Masashi, Nascimbeni, Anna Chiara, Natarajan, Ramesh, Navegantes, Luiz C., Nawrocki, Steffan T., Nazarko, Taras Y., Nazarko, Volodymyr Y., Neill, Thomas, Neri, Luca M., Netea, Mihai G., Netea-Maier, Romana T., Neves, Bruno M., Ney, Paul A., Nezis, Ioannis P., Nguyen, Hang T. T., Nicot, Anne-Sophie, Nilsen, Hilde, Nilsson, Per, Nishimura, Mikio, Nishino, Ichizo, Niso-Santano, Mireia, Niu, Hua, Nixon, Ralph A., Njar, Vincent C. O., Noda, Takeshi, Noegel, Angelika A., Nolte, Elsie Magdalena, Norberg, Erik, Norga, Koenraad K., Noureini, Sakineh Kazemi, Notomi, Shoji, Notterpek, Lucia, Nowikovsky, Karin, Nukina, Nobuyuki, Nuernberger, Thorsten, O'Donnell, Valerie B., O'Donovan, Tracey, O'Dwyer, Peter J., Oehme, Ina, Oeste, Clara L., Ogawa, Michinaga, Ogretmen, Besim, Ogura, Yuji, Oh, Young J., Ohmuraya, Masaki, Ohshima, Takayuki, Ojha, Rani, Okamoto, Koji, Okazaki, Toshiro, Oliver, F. Javier, Ollinger, Karin, Olsson, Stefan, Orban, Daniel P., Ordonez, Paulina, Orhon, Idil, Orosz, Laszlo, O'Rourke, Eyleen J., Orozco, Helena, Ortega, Angel L., Ortona, Elena, Osellame, Laura D., Oshima, Junko, Oshima, Shigeru, Osiewacz, Heinz D., Otomo, Takanobu, Otsu, Kinya, Ou, Jing-hsiung James, Outeiro, Tiago F., Ouyang, Dong-yun, Ouyang, Hongjiao, Overholtzer, Michael, Ozbun, Michelle A., Ozdinler, P. Hande, Ozpolat, Bulent, Pacelli, Consiglia, Paganetti, Paolo, Page, Guylene, Pages, Gilles, Pagnini, Ugo, Pajak, Beata, Pak, Stephen C., Pakos-Zebrucka, Karolina, Pakpour, Nazzy, Palkova, Zdena, Palladino, Francesca, Pallauf, Kathrin, Pallet, Nicolas, Palmieri, Marta, Paludan, Soren R., Palumbo, Camilla, Palumbo, Silvia, Pampliega, Olatz, Pan, Hongming, Pan, Wei, Panaretakis, Theocharis, Pandey, Aseem, Pantazopoulou, Areti, Papackova, Zuzana, Papademetrio, Daniela L., Papassideri, Issidora, Papini, Alessio, Parajuli, Nirmala, Pardo, Julian, Parekh, Vrajesh V., Parenti, Giancarlo, Park, Jong-In, Park, Junsoo, Park, Ohkmae K., Parker, Roy, Parlato, Rosanna, Parys, Jan B., Parzych, Katherine R., Pasquet, Jean-Max, Pasquier, Benoit, Pasumarthi, Kishore B. S., Patschan, Daniel, Patterson, Cam, Pattingre, Sophie, Pattison, Scott, Pause, Arnim, Pavenstaedt, Hermann, Pavone, Flaminia, Pedrozo, Zully, Pena, Fernando J., Penalva, Miguel A., Pende, Mario, Peng, Jianxin, Penna, Fabio, Penninger, Josef M., Pensalfini, Anna, Pepe, Salvatore, Pereira, Gustavo J. S., Pereira, Paulo C., Perez-de la Cruz, Veronica, Esther Perez-Perez, Maria, Perez-Rodriguez, Diego, Perez-Sala, Dolores, Perier, Celine, Perl, Andras, Perlmutter, David H., Perrotta, Ida, Pervaiz, Shazib, Pesonen, Maija, Pessin, Jeffrey E., Peters, Godefridus J., Petersen, Morten, Petrache, Irina, Petrof, Basil J., Petrovski, Goran, Phang, James M., Piacentini, Mauro, Pierdominici, Marina, Pierre, Philippe, Pierrefite-Carle, Valerie, Pietrocola, Federico, Pimentel-Muinos, Felipe X., Pinar, Mario, Pineda, Benjamin, Pinkas-Kramarski, Ronit, Pinti, Marcello, Pinton, Paolo, Piperdi, Bilal, Piret, James M., Platanias, Leonidas C., Platta, Harald W., Plowey, Edward D., Poggeler, Stefanie, Poirot, Marc, Polcic, Peter, Poletti, Angelo, Poon, Audrey H., Popelka, Hana, Popova, Blagovesta, Poprawa, Izabela, Poulose, Shibu M., Poulton, Joanna, Powers, Scott K., Powers, Ted, Pozuelo-Rubio, Mercedes, Prak, Krisna, Prange, Reinhild, Prescott, Mark, Priault, Muriel, Prince, Sharon, Proia, Richard L., Proikas-Cezanne, Tassula, Prokisch, Holger, Promponas, Vasilis J., Przyklenk, Karin, Puertollano, Rosa, Pugazhenthi, Subbiah, Puglielli, Luigi, Pujol, Aurora, Puyal, Julien, Pyeon, Dohun, Qi, Xin, Qian, Wen-bin, Qin, Zheng-Hong, Qiu, Yu, Qu, Ziwei, Quadrilatero, Joe, Quinn, Frederick, Raben, Nina, Rabinowich, Hannah, Radogna, Flavia, Ragusa, Michael J., Rahmani, Mohamed, Raina, Komal, Ramanadham, Sasanka, Ramesh, Rajagopal, Rami, Abdelhaq, Randall-Demllo, Sarron, Randow, Felix, Rao, Hai, Rao, V. Ashutosh, Rasmussen, Blake B., Rasse, Tobias M., Ratovitski, Edward A., Rautou, Pierre-Emmanuel, Ray, Swapan K., Razani, Babak, Reed, Bruce H., Reggiori, Fulvio, Rehm, Markus, Reichert, Andreas S., Rein, Theo, Reiner, David J., Reits, Eric, Ren, Jun, Ren, Xingcong, Renna, Maurizio, Reusch, Jane E. B., Revuelta, Jose L., Reyes, Leticia, Rezaie, Alireza R., Richards, Robert I., Richardson, Des R., Richetta, Clemence, Riehle, Michael A., Rihn, Bertrand H., Rikihisa, Yasuko, Riley, Brigit E., Rimbach, Gerald, Rippo, Maria Rita, Ritis, Konstantinos, Rizzi, Federica, Rizzo, Elizete, Roach, Peter J., Robbins, Jeffrey, Roberge, Michel, Roca, Gabriela, Roccheri, Maria Carmela, Rocha, Sonia, Rodrigues, Cecilia M. P., Rodriguez, Clara I., Rodriguez de Cordoba, Santiago, Rodriguez-Muela, Natalia, Roelofs, Jeroen, Rogov, Vladimir V., Rohn, Troy T., Rohrer, Baerbel, Romanelli, Davide, Romani, Luigina, Silvia Romano, Patricia, Roncero, M. Isabel G., Luis Rosa, Jose, Rosello, Alicia, Rosen, Kirill V., Rosenstiel, Philip, Rost-Roszkowska, Magdalena, Roth, Kevin A., Roue, Gael, Rouis, Mustapha, Rouschop, Kasper M., Ruan, Daniel T., Ruano, Diego, Rubinsztein, David C., Rucker, Edmund B., III, Rudich, Assaf, Rudolf, Emil, Rudolf, Ruediger, Ruegg, Markus A., Ruiz-Roldan, Carmen, Ruparelia, Avnika Ashok, Rusmini, Paola, Russ, David W., Russo, Gian Luigi, Russo, Giuseppe, Russo, Rossella, Rusten, Tor Erik, Ryabovol, Victoria, Ryan, Kevin M., Ryter, Stefan W., Sabatini, David M., Sacher, Michael, Sachse, Carsten, Sack, Michael N., Sadoshima, Junichi, Saftig, Paul, Sagi-Eisenberg, Ronit, Sahni, Sumit, Saikumar, Pothana, Saito, Tsunenori, Saitoh, Tatsuya, Sakakura, Koichi, Sakoh-Nakatogawa, Machiko, Sakuraba, Yasuhito, Salazar-Roa, Maria, Salomoni, Paolo, Saluja, Ashok K., Salvaterra, Paul M., Salvioli, Rosa, Samali, Afshin, Sanchez, Anthony M. J., Sanchez-Alcazar, Jose A., Sanchez-Prieto, Ricardo, Sandri, Marco, Sanjuan, Miguel A., Santaguida, Stefano, Santambrogio, Laura, Santoni, Giorgio, dos Santos, Claudia Nunes, and Saran, Shweta
- Published
- 2016
48. Failed reinnervation in aging skeletal muscle
- Author
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Aare, Sudhakar, primary, Spendiff, Sally, additional, Vuda, Madhusudanarao, additional, Elkrief, Daren, additional, Perez, Anna, additional, Wu, Qinghua, additional, Mayaki, Dominique, additional, Hussain, Sabah N. A., additional, Hettwer, Stefan, additional, and Hepple, Russell T., additional
- Published
- 2016
- Full Text
- View/download PDF
49. Fibulin-5 Regulates Angiopoietin-1/Tie-2 Receptor Signaling in Endothelial Cells
- Author
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Chan, Wilson, primary, Ismail, Hodan, additional, Mayaki, Dominique, additional, Sanchez, Veronica, additional, Tiedemann, Kerstin, additional, Davis, Elaine C., additional, and Hussain, Sabah N. A., additional
- Published
- 2016
- Full Text
- View/download PDF
50. Autophagy and Skeletal Muscles in Sepsis
- Author
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Mofarrahi, Mahroo Sigala, Ioanna Guo, Yeting Godin, Richard and Davis, Elaine C. Petrof, Basil Sandri, Marco Burelle, Yan Hussain, Sabah N. A.
- Abstract
Background: Mitochondrial injury develops in skeletal muscles during the course of severe sepsis. Autophagy is a protein and organelle recycling pathway which functions to degrade or recycle unnecessary, redundant, or inefficient cellular components. No information is available regarding the degree of sepsis-induced mitochondrial injury and autophagy in the ventilatory and locomotor muscles. This study tests the hypotheses that the locomotor muscles are more prone to sepsis-induced mitochondrial injury, depressed biogenesis and autophagy induction compared with the ventilatory muscles. Methodology/Principal Findings: Adult male C57/Bl6 mice were injected with i.p. phosphate buffered saline (PBS) or E. coli lipopolysaccharide (LPS, 20 mg/kg) and sacrificed 24 h later. The tibialis anterior (TA), soleus (SOLD) and diaphragm (DIA) muscles were quickly excised and examined for mitochondrial morphological injury, Ca++ retention capacity and biogenesis. Autophagy was detected with electron microscopy, lipidation of Lc3b proteins and by measuring gene expression of several autophagy-related genes. Electron microscopy revealed ultrastructural injuries in the mitochondria of each muscle, however, injuries were more severe in the TA and SOL muscles than they were in the DIA. Gene expressions of nuclear and mitochondrial DNA transcription factors and co-activators (indicators of biogenesis) were significantly depressed in all treated muscles, although to a greater extent in the TA and SOL muscles. Significant autophagosome formation, Lc3b protein lipidation and upregulation of autophagy-related proteins were detected to a greater extent in the TA and SOL muscles and less so in the DIA. Lipidation of Lc3b and the degree of induction of autophagy-related proteins were significantly blunted in mice expressing a muscle-specific I kappa B alpha superrepresor. Conclusion/Significance: We conclude that locomotor muscles are more prone to sepsis-induced mitochondrial injury, decreased biogenesis and increased autophagy compared with the ventilatory muscles and that autophagy in skeletal muscles during sepsis is regulated in part through the NF kappa B transcription factor.
- Published
- 2012
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