134 results on '"Houben, Geert F."'
Search Results
2. The 50th percentile of the general population single eating occasion intake of food is optimal for the calculation of action levels for precautionary allergen labelling
- Author
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Marty Blom, W., primary, Westerhout, Joost, additional, and Houben, Geert F., additional
- Published
- 2023
- Full Text
- View/download PDF
3. Assessing food allergy risks from residual peanut protein in highly refined vegetable oil
- Author
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Blom, W. Marty, Kruizinga, Astrid G., Rubingh, Carina M., Remington, Ben C., Crevel, René W.R., and Houben, Geert F.
- Published
- 2017
- Full Text
- View/download PDF
4. Accidental allergic reactions to food in adolescents and adults: An overview of the factors involved and implications for prevention
- Author
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Versluis, Astrid, primary, Le, Thuy-My, additional, Houben, Geert F., additional, Knulst, André C., additional, and Van Os-Medendorp, Harmieke, additional
- Published
- 2023
- Full Text
- View/download PDF
5. Precautionary allergen labeling: Current communication problems and potential for future improvements
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Linders, Yvette F.M., Lentz, Leo R., Blom, W. Marty, Michelsen-Huisman, Anouska, Strikwerda, Jelle, Dijk, Liselotte M. van, Knulst, André C., Houben, Geert F., Os-Medendorp, Harmieke van, Holleman, Bregje C., Linders, Yvette F.M., Lentz, Leo R., Blom, W. Marty, Michelsen-Huisman, Anouska, Strikwerda, Jelle, Dijk, Liselotte M. van, Knulst, André C., Houben, Geert F., Os-Medendorp, Harmieke van, and Holleman, Bregje C.
- Abstract
While there are EU laws for priority allergenic ingredients information on food product packaging, there is no legislation about Precautionary Allergen Labelling (PAL) for unintended allergen presence (UAP). As a result, PAL is used in different ways by different manufacturers and retailers, which hampers consumers’ interpretation of the information in the PAL. Previous research has focused on the forms of PAL that are used and on the way they are interpreted and used by consumers. This study adds the perspective of producers, retailers and branch organizations. Thirteen interviews with QA- and QC-professionals were conducted to find out more about the reasoning behind their PAL-use and to find out how PAL could be optimized. Results show that harmonization is needed, on different levels: in the way information on UAP is shared between parties involved in the food chain; in the way PAL is presented and phrased; and in the rules and regulations on PAL. More research is needed on possible ways to share (updates on) information on UAP with consumers.
- Published
- 2023
6. Precautionary allergen labeling: Current communication problems and potential for future improvements
- Author
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ILS L&C, LS OZ vakdidactiek Nederlands, LS OW tekstontwerp en communicatie, LS communicatie- en informatiewetenschap, Linders, Yvette F.M., Lentz, Leo R., Blom, W. Marty, Michelsen-Huisman, Anouska, Strikwerda, Jelle, Dijk, Liselotte M. van, Knulst, André C., Houben, Geert F., Os-Medendorp, Harmieke van, Holleman, Bregje C., ILS L&C, LS OZ vakdidactiek Nederlands, LS OW tekstontwerp en communicatie, LS communicatie- en informatiewetenschap, Linders, Yvette F.M., Lentz, Leo R., Blom, W. Marty, Michelsen-Huisman, Anouska, Strikwerda, Jelle, Dijk, Liselotte M. van, Knulst, André C., Houben, Geert F., Os-Medendorp, Harmieke van, and Holleman, Bregje C.
- Published
- 2023
7. Accidental allergic reactions to food in adolescents and adults: An overview of the factors involved and implications for prevention
- Author
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VS-DIGD, Infection & Immunity, MS Dermatologie/Allergologie, CTI Research, Versluis, Astrid, Le, Thuy-My, Houben, Geert F, Knulst, André C, Van Os-Medendorp, Harmieke, VS-DIGD, Infection & Immunity, MS Dermatologie/Allergologie, CTI Research, Versluis, Astrid, Le, Thuy-My, Houben, Geert F, Knulst, André C, and Van Os-Medendorp, Harmieke
- Published
- 2023
8. Precautionary allergen labeling: Current communication problems and potential for future improvements
- Author
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MS Dermatologie/Allergologie, Infection & Immunity, Afdeling Dietetiek, CTI Research, Afdeling Dermatologie/Allergologie, Linders, Yvette F.M., Lentz, Leo R., Blom, W. Marty, Michelsen-Huisman, Anouska, Strikwerda, Jelle, van Dijk, Liselotte M., Knulst, André C., Houben, Geert F., van Os-Medendorp, Harmieke, Holleman, Bregje C., MS Dermatologie/Allergologie, Infection & Immunity, Afdeling Dietetiek, CTI Research, Afdeling Dermatologie/Allergologie, Linders, Yvette F.M., Lentz, Leo R., Blom, W. Marty, Michelsen-Huisman, Anouska, Strikwerda, Jelle, van Dijk, Liselotte M., Knulst, André C., Houben, Geert F., van Os-Medendorp, Harmieke, and Holleman, Bregje C.
- Published
- 2023
9. Updated full range of Eliciting Dose values for Cow's milk for use in food allergen risk assessment
- Author
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Blom, W. Marty, primary, Westerhout, Joost, additional, Baumert, Joseph L., additional, Meima, Marie Y., additional, Turner, Paul J., additional, Ebisawa, Motohiro, additional, Yanagida, Noriyuki, additional, Remington, Benjamin C., additional, and Houben, Geert F., additional
- Published
- 2022
- Full Text
- View/download PDF
10. Food allergy population thresholds: An evaluation of the number of oral food challenges and dosing schemes on the accuracy of threshold dose distribution modeling
- Author
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Klein Entink, Rinke H., Remington, Benjamin C., Blom, W. Marty, Rubingh, Carina M., Kruizinga, Astrid G., Baumert, Joseph L., Taylor, Steve L., and Houben, Geert F.
- Published
- 2014
- Full Text
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11. Development and evolution of risk assessment for food allergens
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Crevel, René W.R., Baumert, Joseph L., Baka, Athanasia, Houben, Geert F., Knulst, André C., Kruizinga, Astrid G., Luccioli, Stefano, Taylor, Stephen L., and Madsen, Charlotte B.
- Published
- 2014
- Full Text
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12. House dust mite (Der p 10) and crustacean allergic patients may react to food containing Yellow mealworm proteins
- Author
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Verhoeckx, Kitty C.M., van Broekhoven, Sarah, den Hartog-Jager, Constance F., Gaspari, Marco, de Jong, Govardus A.H., Wichers, Harry J., van Hoffen, Els, Houben, Geert F., and Knulst, André C.
- Published
- 2014
- Full Text
- View/download PDF
13. Might gluten traces in wheat substitutes pose a risk in patients with celiac disease? A population-based probabilistic approach to risk estimation
- Author
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Gibert, Anna, Kruizinga, Astrid G, Neuhold, Susanna, Houben, Geert F, Canela, Miguel A, Fasano, Alessio, and Catassi, Carlo
- Published
- 2013
- Full Text
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14. Low dietary adherence after a positive food challenge in food allergic adults
- Author
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VS-DER, Infection & Immunity, MS Dermatologie/Allergologie, Unit Opleiding Dermatologie, Versluis, Astrid, Le, Thuy My, Erp, Francine C.van, Blankestijn, Mark A., Houben, Geert F., Knulst, André C., Os- Medendorp, Harmieke van, VS-DER, Infection & Immunity, MS Dermatologie/Allergologie, Unit Opleiding Dermatologie, Versluis, Astrid, Le, Thuy My, Erp, Francine C.van, Blankestijn, Mark A., Houben, Geert F., Knulst, André C., and Os- Medendorp, Harmieke van
- Published
- 2022
15. Peanut Can Be Used as a Reference Allergen for Hazard Characterization in Food Allergen Risk Management: A Rapid Evidence Assessment and Meta-Analysis
- Author
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MS Dermatologie/Allergologie, Infection & Immunity, Turner, Paul J., Patel, Nandinee, Ballmer-Weber, Barbara K., Baumert, Joe L., Blom, W. Marty, Brooke-Taylor, Simon, Brough, Helen, Campbell, Dianne E., Chen, Hongbing, Chinthrajah, R. Sharon, Crevel, René W.R., Dubois, Anthony E.J., Ebisawa, Motohiro, Elizur, Arnon, Gerdts, Jennifer D., Gowland, M. Hazel, Houben, Geert F., Hourihane, Jonathan O.B., Knulst, André C., La Vieille, Sébastien, López, María Cristina, Mills, E. N.Clare, Polenta, Gustavo A., Purington, Natasha, Said, Maria, Sampson, Hugh A., Schnadt, Sabine, Södergren, Eva, Taylor, Stephen L., Remington, Benjamin C., MS Dermatologie/Allergologie, Infection & Immunity, Turner, Paul J., Patel, Nandinee, Ballmer-Weber, Barbara K., Baumert, Joe L., Blom, W. Marty, Brooke-Taylor, Simon, Brough, Helen, Campbell, Dianne E., Chen, Hongbing, Chinthrajah, R. Sharon, Crevel, René W.R., Dubois, Anthony E.J., Ebisawa, Motohiro, Elizur, Arnon, Gerdts, Jennifer D., Gowland, M. Hazel, Houben, Geert F., Hourihane, Jonathan O.B., Knulst, André C., La Vieille, Sébastien, López, María Cristina, Mills, E. N.Clare, Polenta, Gustavo A., Purington, Natasha, Said, Maria, Sampson, Hugh A., Schnadt, Sabine, Södergren, Eva, Taylor, Stephen L., and Remington, Benjamin C.
- Published
- 2022
16. Peanut Can Be Used as a Reference Allergen for Hazard Characterization in Food Allergen Risk Management: A Rapid Evidence Assessment and Meta-Analysis
- Author
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Turner, Paul J; https://orcid.org/0000-0001-9862-5161, Patel, Nandinee; https://orcid.org/0000-0002-4997-9411, Ballmer-Weber, Barbara K, Baumert, Joe L, Blom, W Marty, Brooke-Taylor, Simon, Brough, Helen; https://orcid.org/0000-0001-7203-0813, Campbell, Dianne E, Chen, Hongbing, Chinthrajah, R Sharon, Crevel, René W R, Dubois, Anthony E J, Ebisawa, Motohiro; https://orcid.org/0000-0003-4117-558X, Elizur, Arnon, Gerdts, Jennifer D, Gowland, M Hazel, Houben, Geert F, Hourihane, Jonathan O B, Knulst, André C, La Vieille, Sébastien, López, María Cristina, Mills, E N Clare, Polenta, Gustavo A, Purington, Natasha, Said, Maria, Sampson, Hugh A, Schnadt, Sabine, Södergren, Eva, Taylor, Stephen L, Remington, Benjamin C, Turner, Paul J; https://orcid.org/0000-0001-9862-5161, Patel, Nandinee; https://orcid.org/0000-0002-4997-9411, Ballmer-Weber, Barbara K, Baumert, Joe L, Blom, W Marty, Brooke-Taylor, Simon, Brough, Helen; https://orcid.org/0000-0001-7203-0813, Campbell, Dianne E, Chen, Hongbing, Chinthrajah, R Sharon, Crevel, René W R, Dubois, Anthony E J, Ebisawa, Motohiro; https://orcid.org/0000-0003-4117-558X, Elizur, Arnon, Gerdts, Jennifer D, Gowland, M Hazel, Houben, Geert F, Hourihane, Jonathan O B, Knulst, André C, La Vieille, Sébastien, López, María Cristina, Mills, E N Clare, Polenta, Gustavo A, Purington, Natasha, Said, Maria, Sampson, Hugh A, Schnadt, Sabine, Södergren, Eva, Taylor, Stephen L, and Remington, Benjamin C
- Abstract
Regional and national legislation mandates the disclosure of “priority” allergens when present as an ingredient in foods, but this does not extend to the unintended presence of allergens due to shared production facilities. This has resulted in a proliferation of precautionary allergen (“may contain”) labels (PAL) that are frequently ignored by food-allergic consumers. Attempts have been made to improve allergen risk management to better inform the use of PAL, but a lack of consensus has led to variety of regulatory approaches and nonuniformity in the use of PAL by food businesses. One potential solution would be to establish internationally agreed “reference doses,” below which no PAL would be needed. However, if reference doses are to be used to inform the need for PAL, then it is essential to characterize the hazard associated with these low-level exposures. For peanut, there are now published data relating to over 3000 double-blind, placebo-controlled challenges in allergic individuals, but a similar level of evidence is lacking for other priority allergens. We present the results of a rapid evidence assessment and meta-analysis for the risk of anaphylaxis to a low-level allergen exposure for priority allergens. On the basis of this analysis, we propose that peanut can and should be considered an exemplar allergen for the hazard characterization at a low-level allergen exposure.
- Published
- 2022
17. 'Too high, too low': the complexities of using thresholds in isolation to inform precautionary allergen ('may contain') labels
- Author
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Turner, Paul J, Baumert, Joseph L, Beyer, Kirsten, Brooke-Taylor, Simon, Comberiati, Pasquale, Crevel, René W R, Gerdts, Jennifer D, Gowland, M Hazel, Houben, Geert F, Hourihane, Jonathan O'B, Konstantinou, George N, La Vieille, Sébastien, Moya, Beatriz, Muraro, Antonella, Mills, E N Clare, Patel, Nandinee, Podestà, Marcia, Popping, Bert, Reese, Imke, Roberts, Graham, Said, Maria, Santos, Alexandra F, Schnadt, Sabine, Taylor, Steve L, Vlieg-Boerstra, Berber, and Remington, Benjamin C
- Subjects
Anaphylaxis ,eliciting dose ,food allergy ,precautionary allergen labelling ,reference dose, thresholds ,Allergy ,EAACI Taskforce on Food allergen thresholds ,Immunology ,thresholds ,reference dose ,Allergens ,Food Labeling ,1107 Immunology ,Immunology and Allergy ,Humans ,Food Hypersensitivity - Published
- 2021
18. Low dietary adherence after a positive food challenge in food allergic adults
- Author
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Versluis, Astrid, primary, Le, Thuy‐My, additional, Erp, Francine C. van, additional, Blankestijn, Mark A., additional, Houben, Geert F., additional, Knulst, André C., additional, and Os‐ Medendorp, Harmieke van, additional
- Published
- 2022
- Full Text
- View/download PDF
19. Poor understanding of allergen labelling by allergic and non-allergic consumers
- Author
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Afdeling Dermatologie/Allergologie, MS Dermatologie/Allergologie, Infection & Immunity, Lab Dermatologie/Allergologie, Afdeling Dietetiek, CTI Research, Holleman, Bregje C., van Os-Medendorp, Harmieke, van den Bergh, Huub, van Dijk, Liselotte M., Linders, Yvette F.M., Blom, W. Marty, Verhoeckx, Kitty C.M., Michelsen-Huisman, Anouska, Houben, Geert F., Knulst, André C., Lentz, Leo R., Afdeling Dermatologie/Allergologie, MS Dermatologie/Allergologie, Infection & Immunity, Lab Dermatologie/Allergologie, Afdeling Dietetiek, CTI Research, Holleman, Bregje C., van Os-Medendorp, Harmieke, van den Bergh, Huub, van Dijk, Liselotte M., Linders, Yvette F.M., Blom, W. Marty, Verhoeckx, Kitty C.M., Michelsen-Huisman, Anouska, Houben, Geert F., Knulst, André C., and Lentz, Leo R.
- Published
- 2021
20. Allergen labelling: Current practice and improvement from a communication perspective
- Author
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MS Dermatologie/Allergologie, Infection & Immunity, Afdeling Dietetiek, CTI Research, Lab Dermatologie/Allergologie, Blom, W Marty, van Dijk, Liselotte M, Michelsen-Huisman, Anouska, Houben, Geert F, Knulst, André C, Linders, Yvette F M, Verhoeckx, Kitty C M, Holleman, Bregje C, Lentz, Leo R, MS Dermatologie/Allergologie, Infection & Immunity, Afdeling Dietetiek, CTI Research, Lab Dermatologie/Allergologie, Blom, W Marty, van Dijk, Liselotte M, Michelsen-Huisman, Anouska, Houben, Geert F, Knulst, André C, Linders, Yvette F M, Verhoeckx, Kitty C M, Holleman, Bregje C, and Lentz, Leo R
- Published
- 2021
21. Accidental food-allergic reactions are associated with higher costs and more sick leave but not with quality of life
- Author
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Poli DER, Infection & Immunity, MS Dermatologie/Allergologie, Versluis, Astrid, Knulst, Andre C, Michelsen-Huisman, Anouska D, Houben, Geert F, Blom, W Marty, Le, Thuy-My, van Os-Medendorp, Harmieke, Poli DER, Infection & Immunity, MS Dermatologie/Allergologie, Versluis, Astrid, Knulst, Andre C, Michelsen-Huisman, Anouska D, Houben, Geert F, Blom, W Marty, Le, Thuy-My, and van Os-Medendorp, Harmieke
- Published
- 2021
22. A systematic comparison of food intake data of the United States and the Netherlands for food allergen risk assessment
- Author
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Meima, Marie Y., primary, Blom, W. Marty, additional, Westerhout, Joost, additional, Kruizinga, Astrid G., additional, Remington, Benjamin C., additional, and Houben, Geert F., additional
- Published
- 2021
- Full Text
- View/download PDF
23. Seeking Windows of Opportunity to Shape Lifelong Immune Health: A Network-Based Strategy to Predict and Prioritize Markers of Early Life Immune Modulation
- Author
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van Bilsen, Jolanda H M, Dulos, Remon, van Stee, Mariël F, Meima, Marie Y, Rouhani Rankouhi, Tanja, Neergaard Jacobsen, Lotte, Staudt Kvistgaard, Anne, Garthoff, Jossie A, Knippels, Léon M J, Knipping, Karen, Houben, Geert F, Verschuren, Lars, Meijerink, Marjolein, Krishnan, Shaji, Afd Pharmacology, Pharmacology, Afd Pharmacology, and Pharmacology
- Subjects
lcsh:Immunologic diseases. Allergy ,0301 basic medicine ,Test strategy ,Immunology ,Psychological intervention ,text mining ,Computational biology ,Biology ,03 medical and health sciences ,Child Development ,0302 clinical medicine ,Immune system ,Acquired immunodeficiency syndrome (AIDS) ,Cytochrome P-450 CYP1A2 ,medicine ,Animals ,Humans ,early life ,Immunology and Allergy ,Gene Regulatory Networks ,Original Research ,Infant, Newborn ,Computational Biology ,Infant ,biomarkers ,FOXP3 ,Forkhead Transcription Factors ,Immune modulation ,medicine.disease ,Early life ,Disease Models, Animal ,machine learning ,030104 developmental biology ,Immune System Diseases ,Immune System ,immune networks ,Chemokines ,lcsh:RC581-607 ,030215 immunology ,Immune activation - Abstract
A healthy immune status is strongly conditioned during early life stages. Insights into the molecular drivers of early life immune development and function are prerequisite to identify strategies to enhance immune health. Even though several starting points for targeted immune modulation have been identified and are being developed into prophylactic or therapeutic approaches, there is no regulatory guidance on how to assess the risk and benefit balance of such interventions. Six early life immune causal networks, each compromising a different time period in early life (the 1st, 2nd, 3rd trimester of gestations, birth, newborn, and infant period), were generated. Thereto information was extracted and structured from early life literature using the automated text mining and machine learning tool: Integrated Network and Dynamical Reasoning Assembler (INDRA). The tool identified relevant entities (e.g., genes/proteins/metabolites/processes/diseases), extracted causal relationships among these entities, and assembled them into early life-immune causal networks. These causal early life immune networks were denoised using GeneMania, enriched with data from the gene-disease association database DisGeNET and Gene Ontology resource tools (GO/GO-SLIM), inferred missing relationships and added expert knowledge to generate information-dense early life immune networks. Analysis of the six early life immune networks by PageRank, not only confirmed the central role of the “commonly used immune markers” (e.g., chemokines, interleukins, IFN, TNF, TGFB, and other immune activation regulators (e.g., CD55, FOXP3, GATA3, CD79A, C4BPA), but also identified less obvious candidates (e.g., CYP1A2, FOXK2, NELFCD, RENBP). Comparison of the different early life periods resulted in the prediction of 11 key early life genes overlapping all early life periods (TNF, IL6, IL10, CD4, FOXP3, IL4, NELFCD, CD79A, IL5, RENBP, and IFNG), and also genes that were only described in certain early life period(s). Concluding, here we describe a network-based approach that provides a science-based and systematical method to explore the functional development of the early life immune system through time. This systems approach aids the generation of a testing strategy for the safety and efficacy of early life immune modulation by predicting the key candidate markers during different phases of early life immune development.
- Published
- 2020
24. Can we define a level of protection for allergic consumers that everyone can accept?
- Author
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Madsen, Charlotte B, van den Dungen, Myrthe W, Cochrane, Stella, Houben, Geert F, Knibb, Rebecca C, Knulst, André C, Ronsmans, Stefan, Yarham, Ross A R, Schnadt, Sabine, Turner, Paul J, Baumert, Joseph, Cavandoli, Elisa, Chan, Chun-Han, Warner, Amena, Crevel, René W R, Madsen, Charlotte B, van den Dungen, Myrthe W, Cochrane, Stella, Houben, Geert F, Knibb, Rebecca C, Knulst, André C, Ronsmans, Stefan, Yarham, Ross A R, Schnadt, Sabine, Turner, Paul J, Baumert, Joseph, Cavandoli, Elisa, Chan, Chun-Han, Warner, Amena, and Crevel, René W R
- Abstract
Substantial progress has been made in characterising the risk associated with exposure to allergens in food. However, absence of agreement on what risk is tolerable has made it difficult to set quantitative limits to manage that risk and protect allergic consumers effectively. This paper reviews scientific progress in the area and the diverse status of allergen management approaches and lack of common standards across different jurisdictions, including within the EU. This lack of regulation largely explains why allergic consumers find Precautionary Allergen Labelling confusing and cannot rely on it. We reviewed approaches to setting quantitative limits for a broad range of food safety hazards to identify the reasoning leading to their adoption. This revealed a diversity of approaches from pragmatic to risk-based, but we could not find clear evidence of the process leading to the decision on risk acceptability. We propose a framework built around the criteria suggested by Murphy and Gardoni (2008) for approaches to defining tolerable risks. Applying these criteria to food allergy, we concluded that sufficient knowledge exists to implement the framework, including sufficient expertise across the whole range of stakeholders to allow opinions to be heard and respected, and a consensus to be achieved.
- Published
- 2020
25. Seeking Windows of Opportunity to Shape Lifelong Immune Health: A Network-Based Strategy to Predict and Prioritize Markers of Early Life Immune Modulation
- Author
-
Afd Pharmacology, Pharmacology, van Bilsen, Jolanda H M, Dulos, Remon, van Stee, Mariël F, Meima, Marie Y, Rouhani Rankouhi, Tanja, Neergaard Jacobsen, Lotte, Staudt Kvistgaard, Anne, Garthoff, Jossie A, Knippels, Léon M J, Knipping, Karen, Houben, Geert F, Verschuren, Lars, Meijerink, Marjolein, Krishnan, Shaji, Afd Pharmacology, Pharmacology, van Bilsen, Jolanda H M, Dulos, Remon, van Stee, Mariël F, Meima, Marie Y, Rouhani Rankouhi, Tanja, Neergaard Jacobsen, Lotte, Staudt Kvistgaard, Anne, Garthoff, Jossie A, Knippels, Léon M J, Knipping, Karen, Houben, Geert F, Verschuren, Lars, Meijerink, Marjolein, and Krishnan, Shaji
- Published
- 2020
26. Can we define a level of protection for allergic consumers that everyone can accept?
- Author
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Madsen, Charlotte Bernhard, van den Dungen, Myrthe W., Cochrane, Stella, Houben, Geert F., Knibb, Rebecca C., Knulst, André C., Ronsmans, Stefan, Yarham, Ross A.R., Schnadt, Sabine, Turner, Paul J., Baumert, Joseph, Cavandoli, Elisa, Chan, Chun Han, Warner, Amena, Crevel, René W.R., Madsen, Charlotte Bernhard, van den Dungen, Myrthe W., Cochrane, Stella, Houben, Geert F., Knibb, Rebecca C., Knulst, André C., Ronsmans, Stefan, Yarham, Ross A.R., Schnadt, Sabine, Turner, Paul J., Baumert, Joseph, Cavandoli, Elisa, Chan, Chun Han, Warner, Amena, and Crevel, René W.R.
- Abstract
Substantial progress has been made in characterising the risk associated with exposure to allergens in food. However, absence of agreement on what risk is tolerable has made it difficult to set quantitative limits to manage that risk and protect allergic consumers effectively. This paper reviews scientific progress in the area and the diverse status of allergen management approaches and lack of common standards across different jurisdictions, including within the EU. This lack of regulation largely explains why allergic consumers find Precautionary Allergen Labelling confusing and cannot rely on it. We reviewed approaches to setting quantitative limits for a broad range of food safety hazards to identify the reasoning leading to their adoption. This revealed a diversity of approaches from pragmatic to risk-based, but we could not find clear evidence of the process leading to the decision on risk acceptability. We propose a framework built around the criteria suggested by Murphy and Gardoni (2008) for approaches to defining tolerable risks. Applying these criteria to food allergy, we concluded that sufficient knowledge exists to implement the framework, including sufficient expertise across the whole range of stakeholders to allow opinions to be heard and respected, and a consensus to be achieved.
- Published
- 2020
27. Allergen risk assessment: Food intake levels of the general population represent those of food allergic patients
- Author
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MS Dermatologie/Allergologie, Infection & Immunity, Afdeling Dermatologie/Allergologie, Afdeling Dietetiek, CTI Research, Blom, W. Marty, van Os-Medendorp, Harmieke, Bijlsma, Sabina, van Dijk, Anne, Kruizinga, Astrid G., Rubingh, Carina, Michelsen-Huisman, Anouska D., Knulst, André C., Houben, Geert F., MS Dermatologie/Allergologie, Infection & Immunity, Afdeling Dermatologie/Allergologie, Afdeling Dietetiek, CTI Research, Blom, W. Marty, van Os-Medendorp, Harmieke, Bijlsma, Sabina, van Dijk, Anne, Kruizinga, Astrid G., Rubingh, Carina, Michelsen-Huisman, Anouska D., Knulst, André C., and Houben, Geert F.
- Published
- 2020
28. Can we define a level of protection for allergic consumers that everyone can accept?
- Author
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CTI Research, Infection & Immunity, MS Dermatologie/Allergologie, Madsen, Charlotte B, van den Dungen, Myrthe W, Cochrane, Stella, Houben, Geert F, Knibb, Rebecca C, Knulst, André C, Ronsmans, Stefan, Yarham, Ross A R, Schnadt, Sabine, Turner, Paul J, Baumert, Joseph, Cavandoli, Elisa, Chan, Chun-Han, Warner, Amena, Crevel, René W R, CTI Research, Infection & Immunity, MS Dermatologie/Allergologie, Madsen, Charlotte B, van den Dungen, Myrthe W, Cochrane, Stella, Houben, Geert F, Knibb, Rebecca C, Knulst, André C, Ronsmans, Stefan, Yarham, Ross A R, Schnadt, Sabine, Turner, Paul J, Baumert, Joseph, Cavandoli, Elisa, Chan, Chun-Han, Warner, Amena, and Crevel, René W R
- Published
- 2020
29. Full range of population Eliciting Dose values for 14 priority allergenic foods and recommendations for use in risk characterization
- Author
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Houben, Geert F., primary, Baumert, Joseph L., additional, Blom, W. Marty, additional, Kruizinga, Astrid G., additional, Meima, Marie Y., additional, Remington, Benjamin C., additional, Wheeler, Matthew W., additional, Westerhout, Joost, additional, and Taylor, Steve L., additional
- Published
- 2020
- Full Text
- View/download PDF
30. Allergen risk assessment: Food intake levels of the general population represent those of food allergic patients
- Author
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Blom, W. Marty, primary, van Os-Medendorp, Harmieke, additional, Bijlsma, Sabina, additional, van Dijk, Anne, additional, Kruizinga, Astrid G., additional, Rubingh, Carina, additional, Michelsen-Huisman, Anouska D., additional, Knulst, André C., additional, and Houben, Geert F., additional
- Published
- 2020
- Full Text
- View/download PDF
31. Updated population minimal eliciting dose distributions for use in risk assessment of 14 priority food allergens
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Remington, Benjamin C., primary, Westerhout, Joost, additional, Meima, Marie Y., additional, Blom, W. Marty, additional, Kruizinga, Astrid G., additional, Wheeler, Matthew W., additional, Taylor, Steve L., additional, Houben, Geert F., additional, and Baumert, Joseph L., additional
- Published
- 2020
- Full Text
- View/download PDF
32. Accidental allergic reactions in food allergy : Causes related to products and patient's management
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Michelsen-Huisman, Anouska D., van Os-Medendorp, Harmieke, Blom, W. Marty, Versluis, Astrid, Castenmiller, Jacqueline J.M., Noteborn, Hubert P.J.M., Kruizinga, Astrid G., Houben, Geert F., and Knulst, André C.
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Immunology ,Immunology and Allergy - Published
- 2018
33. Potential cofactors in accidental food allergic reactions are frequently present but may not influence severity and occurrence
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Versluis, Astrid, van Os-Medendorp, Harmieke, Blom, W. Marty, Michelsen-Huisman, Anouska D., Castenmiller, Jacqueline J.M., Noteborn, Hubert P.J.M., Houben, Geert F., Knulst, André C., Versluis, Astrid, van Os-Medendorp, Harmieke, Blom, W. Marty, Michelsen-Huisman, Anouska D., Castenmiller, Jacqueline J.M., Noteborn, Hubert P.J.M., Houben, Geert F., and Knulst, André C.
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- 2019
34. Deriving individual threshold doses from clinical food challenge data for population risk assessment of food allergens
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Westerhout, Joost, Baumert, Joseph L., Blom, W. Marty, Allen, Katrina J., Ballmer-Weber, Barbara, Crevel, René W.R., Dubois, Anthony E.J., Fernández-Rivas, Montserrat, Greenhawt, Matthew J., Hourihane, Jonathan O.B., Koplin, Jennifer J., Kruizinga, Astrid G., Le, Thuy My, Sampson, Hugh A., Shreffler, Wayne G., Turner, Paul J., Taylor, Steve L., Houben, Geert F., Remington, Benjamin C., Westerhout, Joost, Baumert, Joseph L., Blom, W. Marty, Allen, Katrina J., Ballmer-Weber, Barbara, Crevel, René W.R., Dubois, Anthony E.J., Fernández-Rivas, Montserrat, Greenhawt, Matthew J., Hourihane, Jonathan O.B., Koplin, Jennifer J., Kruizinga, Astrid G., Le, Thuy My, Sampson, Hugh A., Shreffler, Wayne G., Turner, Paul J., Taylor, Steve L., Houben, Geert F., and Remington, Benjamin C.
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- 2019
35. Deriving individual threshold doses from clinical food challenge data for population risk assessment of food allergens
- Author
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MS Dermatologie/Allergologie, Infection & Immunity, Westerhout, Joost, Baumert, Joseph L., Blom, W. Marty, Allen, Katrina J., Ballmer-Weber, Barbara, Crevel, René W.R., Dubois, Anthony E.J., Fernández-Rivas, Montserrat, Greenhawt, Matthew J., Hourihane, Jonathan O.B., Koplin, Jennifer J., Kruizinga, Astrid G., Le, Thuy My, Sampson, Hugh A., Shreffler, Wayne G., Turner, Paul J., Taylor, Steve L., Houben, Geert F., Remington, Benjamin C., MS Dermatologie/Allergologie, Infection & Immunity, Westerhout, Joost, Baumert, Joseph L., Blom, W. Marty, Allen, Katrina J., Ballmer-Weber, Barbara, Crevel, René W.R., Dubois, Anthony E.J., Fernández-Rivas, Montserrat, Greenhawt, Matthew J., Hourihane, Jonathan O.B., Koplin, Jennifer J., Kruizinga, Astrid G., Le, Thuy My, Sampson, Hugh A., Shreffler, Wayne G., Turner, Paul J., Taylor, Steve L., Houben, Geert F., and Remington, Benjamin C.
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- 2019
36. Potential cofactors in accidental food allergic reactions are frequently present but may not influence severity and occurrence
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Verpleegafdeling Dermat./Allerg., UMC Utrecht, Poli DER, Infection & Immunity, Afdeling Dermatologie/Allergologie, MS Dermatologie/Allergologie, Afdeling Dietetiek, Other research (not in main researchprogram), Versluis, Astrid, van Os-Medendorp, Harmieke, Blom, W. Marty, Michelsen-Huisman, Anouska D., Castenmiller, Jacqueline J.M., Noteborn, Hubert P.J.M., Houben, Geert F., Knulst, André C., Verpleegafdeling Dermat./Allerg., UMC Utrecht, Poli DER, Infection & Immunity, Afdeling Dermatologie/Allergologie, MS Dermatologie/Allergologie, Afdeling Dietetiek, Other research (not in main researchprogram), Versluis, Astrid, van Os-Medendorp, Harmieke, Blom, W. Marty, Michelsen-Huisman, Anouska D., Castenmiller, Jacqueline J.M., Noteborn, Hubert P.J.M., Houben, Geert F., and Knulst, André C.
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- 2019
37. Sensitivity analysis to derive a food consumption point estimate for deterministic food allergy risk assessment
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Blom, W. Marty, primary, Remington, Benjamin C., additional, Baumert, Joseph L., additional, Bucchini, Luca, additional, Crépet, Amélie, additional, Crevel, René W.R., additional, Madsen, Charlotte B., additional, Taylor, Steve L., additional, Houben, Geert F., additional, and Kruizinga, Astrid G., additional
- Published
- 2019
- Full Text
- View/download PDF
38. Sensitization to Cor a 9 or Cor a 14 has a strong impact on the distribution of thresholds to hazelnut
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Masthoff, Laury J.N., Blom, W. Marty, Rubingh, Carina M., Klemans, Rob J.B., Remington, Ben C., Bruijnzeel-Koomen, Carla A.F.M., van Hoffen, Els, Houben, Geert F., Meyer, Yolanda, Pasmans, Suzanne G.M.A., Knulst, André C., Masthoff, Laury J.N., Blom, W. Marty, Rubingh, Carina M., Klemans, Rob J.B., Remington, Ben C., Bruijnzeel-Koomen, Carla A.F.M., van Hoffen, Els, Houben, Geert F., Meyer, Yolanda, Pasmans, Suzanne G.M.A., and Knulst, André C.
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- 2018
39. Accidental allergic reactions in food allergy: Causes related to products and patient's management
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Verpleegafdeling Dermat./Allerg., UMC Utrecht, Afdeling Dietetiek, Other research (not in main researchprogram), Infection & Immunity, Afdeling Dermatologie/Allergologie, MS Dermatologie/Allergologie, Poli DER, CTI, Michelsen-Huisman, Anouska D., van Os-Medendorp, Harmieke, Blom, W. Marty, Versluis, Astrid, Castenmiller, Jacqueline J.M., Noteborn, Hubert P.J.M., Kruizinga, Astrid G., Houben, Geert F., Knulst, André C., Verpleegafdeling Dermat./Allerg., UMC Utrecht, Afdeling Dietetiek, Other research (not in main researchprogram), Infection & Immunity, Afdeling Dermatologie/Allergologie, MS Dermatologie/Allergologie, Poli DER, CTI, Michelsen-Huisman, Anouska D., van Os-Medendorp, Harmieke, Blom, W. Marty, Versluis, Astrid, Castenmiller, Jacqueline J.M., Noteborn, Hubert P.J.M., Kruizinga, Astrid G., Houben, Geert F., and Knulst, André C.
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- 2018
40. Sensitization to Cor a 9 or Cor a 14 has a strong impact on the distribution of thresholds to hazelnut
- Author
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Verpleegafdeling Dermat./Allerg., Infection & Immunity, MS Dermatologie/Allergologie, Unit Opleiding Dermatologie, CTI, Masthoff, Laury J.N., Blom, W. Marty, Rubingh, Carina M., Klemans, Rob J.B., Remington, Ben C., Bruijnzeel-Koomen, Carla A.F.M., van Hoffen, Els, Houben, Geert F., Meyer, Yolanda, Pasmans, Suzanne G.M.A., Knulst, André C., Verpleegafdeling Dermat./Allerg., Infection & Immunity, MS Dermatologie/Allergologie, Unit Opleiding Dermatologie, CTI, Masthoff, Laury J.N., Blom, W. Marty, Rubingh, Carina M., Klemans, Rob J.B., Remington, Ben C., Bruijnzeel-Koomen, Carla A.F.M., van Hoffen, Els, Houben, Geert F., Meyer, Yolanda, Pasmans, Suzanne G.M.A., and Knulst, André C.
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- 2018
41. Cofactors in allergic reactions to food : physical exercise and alcohol are the most important
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Versluis, Astrid, Van Os-Medendorp, Harmieke, Kruizinga, Astrid G., Marty Blom, W., Houben, Geert F., and Knulst, André C.
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Adult ,Male ,Alcohol Drinking ,exercise ,Immunology ,cofactor ,Allergens ,Food ,Food allergy ,Journal Article ,Humans ,Immunology and Allergy ,Female ,Anaphylaxis ,Food Hypersensitivity ,Original Research - Abstract
Introduction Involvement of cofactors, like physical exercise, alcohol consumption and use of several types of medication, are associated with more severe food allergic symptoms. However, there is limited evidence on how often cofactors play a role in food allergic reactions. The study aimed to get more insight into the frequency of exposure to cofactors and how often cofactors are associated with more severe symptoms in food allergic patients. Methods A questionnaire was completed by patients visiting the Allergology outpatient clinic. Patients with food allergy were included. Outcome measures were the frequency of medication use of medication groups that might act as cofactor and the frequency that physical exercise, alcohol consumption and use of analgesics are associated with more severe food allergic symptoms. Results Four hundred ninety‐six patients were included in the study. The frequency with which patients used one or more types of medication that might act as cofactors was 7.7%: antacids/acid neutralizing medication (5%), NSAIDs (2%), beta blockers (0.6%), angiotensin‐converting enzyme inhibitors (0.6%), and angiotensin receptor blockers (0.2%). Of all patients, 13% reported more severe symptoms to food after involvement of one or more of the cofactors: physical exercise (10%), alcohol consumption (5%), and use of analgesics (0.6%). Sixty‐five percent did not know if these cofactors caused more severe symptoms; 22% reported that these cofactors had no effect. Conclusions Only a small percentage of patients (7.7%) used medication that might aggravate food allergic reactions. Physical exercise and alcohol consumption were the most frequently reported cofactors, but occurring still in only 10% or less.
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- 2016
42. Is mealworm or shrimp allergy indicative for food allergy to insects?
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Broekman, Henrike C.H.P., Knulst, André C., de Jong, Govardus, Gaspari, Marco, den Hartog Jager, Constance F., Houben, Geert F., Verhoeckx, Kitty C.M., Broekman, Henrike C.H.P., Knulst, André C., de Jong, Govardus, Gaspari, Marco, den Hartog Jager, Constance F., Houben, Geert F., and Verhoeckx, Kitty C.M.
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- 2017
43. Specific IgE to Jug r 1 has no additional value compared with extract-based testing in diagnosing walnut allergy in adults
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Blankestijn, Mark, Blom, Marty, Otten, Henry G., Baumert, Joseph L., Taylor, Steve L., Bruijnzeel-Koomen, Carla A F M, Houben, Geert F, Knulst, André C, Klemans, Rob J B, Blankestijn, Mark, Blom, Marty, Otten, Henry G., Baumert, Joseph L., Taylor, Steve L., Bruijnzeel-Koomen, Carla A F M, Houben, Geert F, Knulst, André C, and Klemans, Rob J B
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- 2017
44. Abstracts from the Food Allergy and Anaphylaxis Meeting 2016
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Pouessel, Guillaume, Claverie, Claire, Labreuche, Julien, Renaudin, Jean-Marie, Dorkenoo, Aimée, Eb, Mireille, Moneret-Vautrin, Anne, Deschildre, Antoine, Leteurtre, Stephane, Grabenhenrich, Linus, Worm, Margitta, Dölle, Sabine, Scherer, Kathrin, Hutteger, Isidor, Christensen, Morten, Bindslev-Jensen, Carsten, Mortz, Charlotte, Eller, Esben, Kjaer, Henrik F, Carneiro-Leão, Leonor, Badas, Jenny, Coimbra, Alice, Levy, Dikla P, Ben-Shoshan, Moshe, Rimon, Ayelet, Benor, Shira, Arends, Nicolette J T, Edelbroek, Nikki, de Groot, Hans, Emons, Joyce A M, Brand, H. K A, Verhoeven, Dirk, van Veen, Leonieke N, de Jong, Nicolette W, Noh, Geunwoong, Jang, Eun H, Pascal, Mariona, Dominguez, Olga, Piquer, Mònica, Alvaro, Montserrat, Jimenez-Feijoo, Rosa, Lozano, Jaime, Machinena, Adriana, del Mar Folqué, Maria, Giner, Maria T, Plaza, Ana M, Turner, Paul, Patel, Nandinee, Vazquez-Ortiz, Marta, Lindsley, Sarah, Walker, Lucy, Rosenberg, Simon, Mari, Adriano, Alessandri, Claudia, Giangrieco, Ivana, Tuppo, Lisa, Rafaiani, Chiara, Mitterer, Georg, Ciancamerla, Michela, Ferrara, Rosetta, Bernardi, Maria L, Zennaro, Danila, Tamburrini, Maurizio, Ciardiello, Maria A, Harwanegg, Christian, Fernandez, Antonio, Selb, Regina, Egenmann, Philippe, Epstein, Michelle, Hoffmann-Sommergruber, Karin, Koning, Frits, Lovik, Martinus, Clare Mills, E. N, Moreno, Javier, van Loveren, Henk, Wal, Jean-Michel, Diesner, Susanne, Bergmayr, Cornelia, Pfitzner, Barbara, Assmann, Vera E, Starkl, Philipp, Endesfelder, David, Eiwegger, Thomas, Szepfalusi, Zsolt, Fehrenbach, Heinz, Jensen-Jarolim, Erika, Hartmann, Anton, Pali-Schöll, Isabella, Untersmayr, Eva, Wille, Soren, Meyer, Peter, Klingebiel, Caroline, Lidholm, Jonas, Ehrenberg, Angelica, Östling, Jonas, Cleach, Isabelle, Mège, Jean-Louis, Vitte, Joana, Aina, Roberta, Dubiela, Pawel, Pfeifer, Sabine, Bublin, Merima, Radauer, Christian, Humeniuk, Piotr, Kabasser, Stefan, Asero, Riccardo, Bogas, Gador, Gomez, Francisca, Campo, Paloma, Salas, Maria, Doña, Inmaculada, Barrionuevo, Esther, Guerrero, Maria A, Mayorga, Cristobalina, Prieto, Ana, Barber, Domingo, Torres, Maria J, Jamin, Annette, Wangorsch, Andrea, Ballmer, Barbara, Vieths, Stefan, Scheurer, Stephan, Apostolovic, Danijela, Mihailovic, Jelena, Krstic, Maja, Starkhammar, Maria, Velickovic, Tanja C, Hamsten, Carl, van Hage, Marianne, van Erp, Francine C, Knol, Edward F, Kansen, Hannah M, Pontoppidan, Bo, Meijer, Yolanda, van der Ent, Cornelis K, Knulst, André C, Sayers, Rebekah, Brown, Helen, Custovic, Adnan, Simpson, Angela, Mills, Claire, Schulz, Juliane, Akkerdaas, Jaap, Totis, Muriel, Capt, Annabelle, Herouet-Guicheney, Corinne, van Ree, Ronald, Banerjee, Tushar, Banerjee, Antima, Claude, Mathilde, Bouchaud, Grégory, Lupi, Roberta, Castan, Laure, Tranquet, Olivier, Denery-Papini, Sandra, Bodinier, Marie, Brossard, Chantal, De Poi, Rosella, Gritti, Elisa, De Dominicis, Emiliano, Popping, Bert, de Laureto, Patrizia P, Palosuo, Kati, Kukkonen, Anna K, Pelkonen, Anna, Mäkelä, Mika, Lee, Nanju A, Rost, Johanna, Muralidharan, Sridevi, Campbell, Dianne, Mehr, Sam, Nock, Catherine, Baumert, Joseph, Taylor, Steve, Mastrorilli, Carla, Tripodi, Salvatore, Caffarelli, Carlo, Perna, Serena, Di Rienzo Businco, Andrea, Sfika, Ifigenia, Dondi, Arianna, Bianchi, Annamaria, Dascola, Carlotta P, Ricci, Giampaolo, Cipriani, Francesca, Maiello, Nunzia, del Giudice, Michele M, Frediani, Tullio, Frediani, Simone, Macrì, Francesco, Pistoletti, Chiara, Iacono, Iride D, Patria, Maria F, Varin, Elena, Peroni, Diego, Comberiati, Pasquale, Chini, Loredana, Moschese, Viviana, Lucarelli, Sandra, Bernardini, Roberto, Pingitore, Giuseppe, Pelosi, Umberto, Olcese, Roberta, Moretti, Matteo, Cirisano, Anastasia, Faggian, Diego, Travaglini, Alessandro, Plebani, Mario, Verga, Maria C, Calvani, Mauro, Giordani, Paolo, Matricardi, Paolo M, Ontiveros, Noe, Cabrera-Chavez, Francisco, Galand, Julie, Beaudouin, Etienne, Pineau, Florence, Sakai, Shinobu, Matsunaga, Kayoko, Teshima, Reiko, Larré, Colette, Denery, Sandra, Tschirner, Sebastian, Trendelenburg, Valérie, Schulz, Gabriele, Niggemann, Bodo, Beyer, Kirsten, Bouferkas, Youcef, Belabbas, Younes, Saidi, Djamel, Kheroua, Omar, Mecherfi, Kamel E E, Guendouz, Malika, Haddi, Abir, Kaddouri, Hanane, Amaral, Luis, Pereira, Ana, Rodrigues, Susana, Datema, Mareen, Jongejan, Laurian, Clausen, Michael, Knulst, Andre, Papadopoulos, Nikolaos, Kowalski, Marek, de Blay, Frédéric, Zwinderman, Aeilko, Hoffman-Sommergruber, Karin, Ballmer-Weber, Barbara, Fernandez-Rivas, Montserrat, Deng, Shan, Yin, Jia, Eisenmann, Charlotte, Nassiri, Maria, Reinert, Rabea, van der Valk, Johanna P M, van Wijk, Roy G, Vergouwe, Yvonne, Steyerberg, Ewout W, Reitsma, Marit, Wichers, Harry J, Savelkoul, Huub F J, Vlieg-Boerstra, Berber, Dubois, Anthony E J, Carolino, Fabrícia, Rodolfo, Ana, Cernadas, Josefina, Roa-Medellín, Dasha, Rodriguez-Fernandez, Ana, Navarro, Joaquín, Albendiz, Vicente, Baeza, María L, Intente-Herrero, Sonsoles, Mikkelsen, Andrea, Mehlig, Kirsten, Lissner, Lauren, Verrill, Linda, Luccioli, Stefano, van Bilsen, Jolanda, Kuper, Frieke, Wolterbeek, André, Rankouhi, Tanja R, Verschuren, Lars, Cnossen, Hilde, Jeurink, Prescilla, Garssen, Johan, Knippels, Léon, Garthoff, Jossie, Houben, Geert, Leeman, Winfried, Eleonore Pettersson, M., Schins, Afke M M, Koppelman, Gerard H, Kollen, Boudewjin J, Zubchenko, Svitlana, Kuntz, Sarah, Mérida, Pablo, Álvaro, Montserrat, Piquer, Monica, Riggioni, Carmen, Castellanos, Juan H, Jimenez, Rosa, Cap, Melanie, Drumez, Elodie, Lejeune, Stéphanie, Thumerelle, Caroline, Mordacq, Clémence, Nève, Véronique, Ricò, Sonia, Varini, Margherita, Nocerino, Rita, Cosenza, Linda, Amoroso, Antonio, Di Costanzo, Margherita, Di Scala, Carmen, Bedogni, Giorgio, Canani, Roberto B, Turner, Paul J, Poza-Guedes, Paloma, González-Pérez, Ruperto, Sánchez-Machín, Inmaculada, Matheu-Delgado, Victor, Wambre, Erik, Ballegaard, Anne-Sofie, Madsen, Charlotte, Gregersen, Juliane, Bøgh, Katrine L, Aubert, Philippe, Neunlist, Michel, Magnan, Antoine, Lozano-Ojalvo, Daniel, Pablos-Tanarro, Alba, Pérez-Rodríguez, Leticia, Molina, Elena, López-Fandiño, Rosina, Rekima, Akila, Macchiaverni, Patricia, Turfkruyer, Mathilde, Holvoet, Sebastien, Dupuis, Lénaïck, Baiz, Nour, Annesi-Maesano, Isabella, Mercenier, Annick, Nutten, Sophie, Verhasselt, Valérie, Mrakovcic-Sutic, Ines, Banac, Srdan, Sutic, Ivana, Baricev-Novakovic, Zdenka, Sutic, Ingrid, Pavisic, Valentino, Muñoz-Cano, Rosa, Jiménez-Rodríguez, Teodoríkez, Corbacho, Daniel, Roca-Ferrer, Jordi, Bartra, Joan, Bulog, Aleksandar, Micovic, Vladimir, Markiewicz, Lidia, Szymkiewicz, Agata, Szyc, Anna, Wróblewska, Barbara, Harvey, Bryan M, Harthoorn, Lucien F, Wesley Burks, A., Rentzos, Georgios, Björk, Anna-Lena B, Bengtsson, Ulf, Barber, Colin, Kalicinsky, Chrystyna, Breynaert, Christine, Coorevits, Lieve, Jansen, Cornelia, Van Hoeyveld, Erna, Verbeke, Kristin, Kochuyt, Anne-Marie, Schrijvers, Rik, Deleanu, Diana, Muntean, Adriana, Konstantakopoulou, Maria, Pasioti, Maria, Papadopoulou, Anastasia, Iliopoulou, Anna, Mikos, Nikolaos, Kompoti, Evangelia, de Castro, Eunice D, Bartalomé, Borja, Ue, Kok L, Griffiths, Elizabeth, Till, Stephen, Grimshaw, Kate, Roberts, Graham, Selby, Anna, Butiene, Indre, Larco, Jose I, Dubakiene, Ruta, Fiandor, Ana, Fiocchi, Alessandro, Papadopoulos, Nikos, Sigurdardottir, Sigurveig, Sprikkelman, Aline, Schoemaker, Anne-Fleur, Xepapadaki, Paraskevi, Keil, Thomas, Cojocariu, Zizi, Barbado, Beatriz S, Iancu, Vasti, Arroabarren, Esozia, Esarte, Marta G, Arteaga, Miren, Andrade, Mayra C, Borges, Denise, Kalil, Jorge, Bianchi, Pedro G, Agondi, Rosana C, Gupta, Rinkesh K, Sharma, Akanksha, Gupta, Kriti, Das, Mukul, Dwivedi, Premendra, Karseladze, Rusudan, Jorjoliani, Liana, Saginadze, Lali, Tskhakaia, Mariam, Basello, Katia, Piuri, Gabriele, Speciani, Attilio F, Speciani, Michela C, Camerotto, Carla, Zinno, Francesco, Pakholchuk, Olga, Nedelska, Svitlana, Pattini, Stefano, Costantino, Maria T, Peveri, Silvia, Villalta, Danilo, Savi, Eleonora, Costanzi, Andrea, Revyakina, Vera A, Kiseleva, Marina A, Kuvshinova, Elena D, Larkova, Inna A, Shekhetov, Anton A, Silva, Diana, Moreira, André, Plácido, José, van der Kleij, Hanneke, van Twuijver, Esther, Sutorius, Robbert, de Kam, Pieter-Jan, van Odijk, Jenny, Lindqvist, Helen, Lustig, Elin, Jácome, Amyra A A, Aguilar, Karla L B, Domínguez, Miguel G, Hernández, David A M, Caruso, Cristiano, Casale, Cono, Rapaccini, Gian L, Romano, Antonino, De Vitis, Italo, Cocco, Renata R, Aranda, Carolina, Mallozi, Marcia C, Motta, Jackeline F, Moraes, Lilian, Pastorino, Antonio, Rosario, Nelson, Goudouris, Ekaterini, Porto, Arnaldo, Wandalsen, Neusa F, Sarinho, Emanuel, Sano, Flavio, Solé, Dirceu, Pitsios, Constantinos, Petrodimopoulou, Maria, Papadopoulou, Ekaterini, Passioti, Maria, Kontogianni, Meropi, Adamia, Nino, Khaleva, Ekaterina, del Prado, Ana P, Du Toit, George, Krzych, Edyta, Samolinska-Zawisza, Urszula, Furmanczyk, Konrad, Tomaszewska, Aneta, Raciborski, Filip, Lipiec, Agnieszka, Samel-Kowalik, Piotr, Walkiewicz, Artur, Borowicz, Jacek, Samolinski, Boleslaw, Nano, Aimee L, Recto, Marysia, Somoza, Maria L, López, Natalia B, Alzate, Diana P, Ruano, Francisco J, Garcimartín, Maria I, Haroun, Elisa, de la Torre, Maria V, Rojas, Antonia, Onieva, Montserrat L, 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Astrid G, Versluis, Astrid, van Duijn, Gert, de Zeeuw-Brouwer, H. M, Castenmiller, Jacqueline J M, Noteborn, Hub P J M, Houben, Geert F, Bravin, Kristian, Luyt, David, Javed, Bushra, Couch, Phil, Munro, Christopher, Padfield, Phil, Sperrin, Matt, Byrne, Aideen, Oosthuizen, Lizalet, Kelleher, Carina, Ward, Fiona, Brosnan, Niamh, King, Graham, Corbet, Eva, Guzmán, Josué A H, García, Montserrat B, Asensio, Oscar, Navarrete, Laura V, Larramona, Helena, Miró, Xavier D, Pyrz, Katarzyna, Austin, Moira, Boloh, Yanne, Couch, Philip, Galloway, Deirdre, Hernandez, Pilar, Hourihane, Jonathan O, Kenna, Fiona, Majkowska-Wojciechowska, Barbara, Regent, Lynne, Themisb, Marina, Schnadt, Sabine, Semic-Jusufagic, Aida, Galvin, Audrey D, Kauppila, Tiina, Kuitunen, Mikael, Kitsioulis, Nikolaos A, Douladiris, Nikolaos, Kostoudi, Sofia, Manolaraki, Ioanna, Mitsias, Dimitris, Manousakis, Emmanouil, Papadopoulos, Nikolaos G, Knibb, Rebecca, Hammond, Jennifer, Cooke, Richard, Yrjänä, Jaakko, Hanni, Anna-Maija, Vähäsarja, Päivi, Mustonen, Oona, Dunder, Teija, Kulmala, Petri, Lasa, Eva, D’Amelio, Carmen, Martínez, Sara, Joral, Alejandro, Gastaminza, Gabriel, Goikoetxea, Maria J, Candy, David C A, Van Ampting, Marleen T J, Oude Nijhuis, Manon M, Butt, Assad M, Peroni, Diego G, Fox, Adam T, Knol, Jan, Michaelis, Louise J, Padua, Ines, Padrao, Patricia, Moreira, Pedro, Barros, Renata, Sharif, Hanan, Ahmed, Manzoor, Gomaa, Nehad, Mens, Joris, Smit, Koen, Timmermans, Frans, Poredoš, Tomaž, Jeverica, Anja K, Sedmak, Marjeta, Benedik, Evgen, Accetto, Meta, Zupančič, Mirjana, Yonamine, Glauce, Soldateli, Gustavo, Aquilante, Bruna, Pastorino, Antonio C, de Moraes Beck, Cleonir L, Gushken, Andrea K, de Barros Dorna, Mayra, dos Santos, Cristiane N, Castro, Ana P M, Al-Qahtani, Abdulhadi, Arnaout, Rand, Khaliq, Agha R, Amin, Rashid, Sheikh, Farrukh, Alvarez, Jorge, Anda, Marta, Palacios, Miriam, De Prada, Montserrat, Ponce, Carmen, Balbino, Bianca, Sibilano, Riccardo, Marichal, Thomas, Gaudenzio, Nicolas, Karasuyama, Hajime, Bruhns, Pierre, Tsai, Mindy, Reber, Laurent L, Galli, Stephen J, Ferreira, Ana R, Cernadas, Josefina R, del Campo García, Aida, Fernández, Sara P, Carrera, Nerea S, Sánchez-Cruz, Fernando B, Lorenzo, José R F, Claus, Stephanie, Pföhler, Claudia, Ruëff, Franziska, Treudler, Regina, Jaume, Mercedes E, Madroñero, Agustin, Perez, Maria T G, Julia, Juan C, Plovdiv, Charlotte H, Gethings, Lee, Langridge, Jim, Adel-Patient, Karine, Bernard, Hervé, Barcievic-Jones, Ivona, Sokolova, Raditsa, Yankova, Rumyana, Ivanovska, Mariya, Murdjeva, Marianna, Popova, Tatyana, Dermendzhiev, Svetlan, Karjalainen, Martin, Lehnigk, Ulrike, Brown, Duncan, Locklear, Julie C, Locklear, Julie, Maris, Ioana, Hourihane, Jonathan, Ornelas, Cristina, Caiado, Joana, Ferreira, Manuel B, Pereira-Barbosa, Manuel, Puente, Yolanda, Daza, Juan C, Monteseirin, Francisco J, Ukleja-Sokolowska, Natalia, Gawronska-Ukleja, Ewa, Zbikowska-Gotz, Magdalena, Bartuzi, Zbigniew, Sokolowski, Lukasz, Adams, Aine, Mahon, Bernard, English, Karen, Gourdon-Dubois, Nelly, Sellam, Laetitia, Pereira, Bruno, Michaud, Elodie, Messaoudi, Khaled, Evrard, Bertrand, Fauquert, Jean-Luc, Palomares, Francisca, Gomez, Gador, Rodriguez, Maria J, Galindo, Luisa, Molina, Ana, Paparo, Lorella, Mennini, Maurizio, Aitoro, Rosita, Wawrzeńczyk, Adam, Przybyszewski, Michał, Wawrzeńczyk, Anna, Sarıcoban, Hulya E, Ugras, Meltem, Yalvac, Zerrin, Flokstra-de Blok, Bertine M J, van der Velde, J. L, Vereda, Andrea, Ippolito, Clara, Traversa, Amaranta, Adriano, Daniela, Bianchi, Daniela M, Gallina, Silvia, Decastelli, Lucia, Makatsori, Melina, Miles, Anne, Devetak, Sonja P, Devetak, Iztok, Tabet, Soraya A, Trandbohus, Jeanette F, Winther, Pernille, Malling, Hans-Jørgen, Hansen, Kirsten S, Garvey, Lene H, Wang, Chia-Chi, Cheng, Yin-Hua, Tung, Chun-Wei, Dietrich, Mariola, Marenholz, Ingo, Kalb, Birgit, Grosche, Sarah, Blümchen, Katharina, Schlags, Rupert, Price, Mareike, Rietz, Sylke, Esparza-Gordillo, Jorge, Lau, Susanne, Lee, Young-Ae, Almontasheri, Ali, Bahkali, Mohammad A, Elshorbagi, Sahar, Alfhaid, Abdullah, Altamimi, Mashary, Madbouly, Eman, Al-Dhekri, Hassan, Arnaout, Rand K, Basagaña, Maria, Miquel, Sira, Bartolomé, Borja, Brix, Bettina, Rohwer, Stefanie, Brandhoff, Sandra, Berger, Alena, Suer, Waltraud, Weimann, Alf, Bueno, Cristina, Martín-Pedraza, Laura, Abián, Sara, Segundo-Acosta, Pablo S, López-Rodríguez, Juan C, Barderas, Rodrigo, Batanero, Eva, Cuesta-Herranz, Javier, Villalba, María T, Correia, Magna, Benito-Garcia, Filipe, Arêde, Cristina, Piedade, Susana, Morais-Almeida, Mário, Hindley, James, Yarham, Ross, Kuklinska-Pijanka, Anna, Gillick, David, Patient, Karine, Chapman, Martin D, Miranda, Ana, Matos, Eugénia, Sokolova, Anna, Rao, Huan, Baricevic-Jones, Ivona, Smith, Frances, Xue, Wentong, Magnusdottir, Helga, Vidarsdottir, Anna G, Lund, Sigrun, Jensen, Anders B, Ludviksson, Bjorn R, Simon, Reyna, Elfont, Robert, Bennett, Sean, Voyksner, Robert, de Lurdes Torre, Maria, Yürek, Songül, Faber, Margaretha A, Bastiaensen, Annick, Mangodt, Evelyne, van Gasse, Athina, Decuyper, Ine, Sabato, Vito, Hagendorens, Margo M, Bridts, Chris H, De Clerck, Luc S, Ebo, Didier, Schwarz, Susanne, Ziegert, Mandy, Albroscheit, Saskia, Schwager, Christian, Kull, Skadi, Behrends, Jochen, Röckendorf, Niels, Schocker, Frauke, Frey, Andreas, Homann, Arne, Becker, Wolf-Meinhard, Jappe, Uta, Zaabat, Nesrine, Osscini, Sylvia, Agabriel, Chantal, Sterling, Benoît, Carsin, Ania, Liabeuf, Valérie, Maćków, Monica, Zbróg, Alina, Bronkowska, Monica, Courtois, Justine, Gadisseur, Romy, Bertholet, Catherine, Lukas, Pierre, Cavalier, Etienne, Delahaut, Philippe, Quinting, Birgit, Gertmo, Margareta B, Hasseus, Ewa T, Barzylovych, Vladyslava, Oliveira, Júlio, Ensina, Luis F, Aranda, Carolina S, Dopazo, Leire, Lopez, Rebeca, Perez, Raquel, Santos-Diez, Laura, Bilbao, Agurtzane, Garcia, Juan M, Núñez, Ignacio G, Mármol, María Á A, Villarejo, María J B, Martos, José A B, Vergara, Marina S, García, José M I, Michalska, Agata, Sergiejko, Grzegorz, Zacniewski, Robert, Ghiordanescu, Ileana-Maria, Deaconu, Cristina, Popescu, Mihaela, Bumbacea, Roxana S, Ibranji, Alkerta, Nikolla, Elida, Loloci, Gjustina, Juel-Berg, Nanna, Larsen, Lau F, Poulsen, Lars K, Marcelino, João, Prata, Ricardo, Costa, Ana C, Duarte, Fátima, Neto, Marta, Santos, Jennifer, Pestana, Luís C, Sampaio, Daniel, Minale, Paola, Dignetti, Paola, Bignardi, Donatella, Nedelea, Irena, Popescu, Florin-Dan, Vieru, Mariana, Secureanu, Florin-Adrian, Ganea, Carmen S, Vieira, Miguel, Silva, José P M, Watts, Timothy, Watts, Sophia, Lomikovska, Marta, Peredelskaya, Marina, Nenasheva, Natalia, Filipovic, Ivana, Zivkovic, Zorica, Filipovic, Djordje, Higgs, Jennette, Warner, Amena, and Jones, Carla
- Published
- 2017
45. Is mealworm or shrimp allergy indicative for food allergy to insects?
- Author
-
Unit Opleiding Dermatologie, MS Dermatologie/Allergologie, Infection & Immunity, CTI, Broekman, Henrike C.H.P., Knulst, André C., de Jong, Govardus, Gaspari, Marco, den Hartog Jager, Constance F., Houben, Geert F., Verhoeckx, Kitty C.M., Unit Opleiding Dermatologie, MS Dermatologie/Allergologie, Infection & Immunity, CTI, Broekman, Henrike C.H.P., Knulst, André C., de Jong, Govardus, Gaspari, Marco, den Hartog Jager, Constance F., Houben, Geert F., and Verhoeckx, Kitty C.M.
- Published
- 2017
46. Specific IgE to Jug r 1 has no additional value compared with extract-based testing in diagnosing walnut allergy in adults
- Author
-
MS Dermatologie/Allergologie, Infection & Immunity, CDL Celdiagnostiek, DIGD-Medisch 1, Unit Opleiding Dermatologie, Blankestijn, Mark, Blom, Marty, Otten, Henry G., Baumert, Joseph L., Taylor, Steve L., Bruijnzeel-Koomen, Carla A F M, Houben, Geert F, Knulst, André C, Klemans, Rob J B, MS Dermatologie/Allergologie, Infection & Immunity, CDL Celdiagnostiek, DIGD-Medisch 1, Unit Opleiding Dermatologie, Blankestijn, Mark, Blom, Marty, Otten, Henry G., Baumert, Joseph L., Taylor, Steve L., Bruijnzeel-Koomen, Carla A F M, Houben, Geert F, Knulst, André C, and Klemans, Rob J B
- Published
- 2017
47. Majority of shrimp-allergic patients are allergic to mealworm
- Author
-
Broekman, Henrike, Verhoeckx, Kitty C., Den Hartog Jager, Constance F., Kruizinga, Astrid G., Pronk-Kleinjan, Marieke, Remington, Benjamin C., Bruijnzeel-Koomen, Carla A., Houben, Geert F., Knulst, André C., Broekman, Henrike, Verhoeckx, Kitty C., Den Hartog Jager, Constance F., Kruizinga, Astrid G., Pronk-Kleinjan, Marieke, Remington, Benjamin C., Bruijnzeel-Koomen, Carla A., Houben, Geert F., and Knulst, André C.
- Published
- 2016
48. Cofactors in allergic reactions to food: physical exercise and alcohol are the most important
- Author
-
UMC Utrecht, Poli DER, Infection & Immunity, Afdeling Dermatologie/Allergologie, MS Dermatologie/Allergologie, Versluis, Astrid, Van Os-Medendorp, Harmieke, Kruizinga, Astrid G., Marty Blom, W., Houben, Geert F., Knulst, André C., UMC Utrecht, Poli DER, Infection & Immunity, Afdeling Dermatologie/Allergologie, MS Dermatologie/Allergologie, Versluis, Astrid, Van Os-Medendorp, Harmieke, Kruizinga, Astrid G., Marty Blom, W., Houben, Geert F., and Knulst, André C.
- Published
- 2016
49. Majority of shrimp-allergic patients are allergic to mealworm
- Author
-
MS Dermatologie/Allergologie, Infection & Immunity, DIGD-Medisch 1, Broekman, Henrike, Verhoeckx, Kitty C., Den Hartog Jager, Constance F., Kruizinga, Astrid G., Pronk-Kleinjan, Marieke, Remington, Benjamin C., Bruijnzeel-Koomen, Carla A., Houben, Geert F., Knulst, André C., MS Dermatologie/Allergologie, Infection & Immunity, DIGD-Medisch 1, Broekman, Henrike, Verhoeckx, Kitty C., Den Hartog Jager, Constance F., Kruizinga, Astrid G., Pronk-Kleinjan, Marieke, Remington, Benjamin C., Bruijnzeel-Koomen, Carla A., Houben, Geert F., and Knulst, André C.
- Published
- 2016
50. Understanding food allergen thresholds requires careful analysis of the available clinical data
- Author
-
Taylor, Steve L., Houben, Geert F., Baumert, Joseph L., Crevel, Rene R W R, Allen, Katrina J., Dubois, Anthony E J, Knulst, Andre C., Remington, Benjamin C., Kruizinga, Astrid G., Blom, W. Marty, Brooke-Taylor, Simon, Taylor, Steve L., Houben, Geert F., Baumert, Joseph L., Crevel, Rene R W R, Allen, Katrina J., Dubois, Anthony E J, Knulst, Andre C., Remington, Benjamin C., Kruizinga, Astrid G., Blom, W. Marty, and Brooke-Taylor, Simon
- Published
- 2015
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