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Your search keyword '"Hellenbeck, Paul L."' showing total 2 results
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2 results on '"Hellenbeck, Paul L."'

1. Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models

Author

Zhang, Huiyuan, Du, Yuchen, Qi, Lin, Xiao, Sophie, Braun, Frank K., Kogiso, Mari, Huang, Yulun, Huang, Frank, Abdallah, Aalaa, Suarez, Milagros, Karthick, Sekar, Ahmed, Nabil M., Salsman, Vita S., Baxter, Patricia A., Su, Jack M., Brat, Daniel J., Hellenbeck, Paul L., Teo, Wan-Yee, Patel, Akash J., and Li, Xiao-Nan

Published
2023
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2. DNA binding and heteromerization of the Drosophila transcription factor chorion factor 1/ultraspiracle

Author

Christianson, Anastasia M. Khoury, King, Dennis L., Hatzivassiliou, Evie, Casas, Jorge E., Hellenbeck, Paul L., Nikodem, Vera M., Mitsialis, S. Alex, and Kafatos, F.C.

Subjects
Drosophila -- Physiological aspects, Genetic transcription -- Regulation, DNA binding proteins -- Identification and classification, Science and technology
Abstract

The in vitro DNA-binding properties and distribution of the Drosophila chorion factor 1/ultraspiracle transcription factor (CF1/USP) were investigated. The study protocol involved the use of monoclonal antibodies and bacterially produced full-length protein. The results showed that CF1/USP bindsmoderately strongly to a single hormone response element half-site. However, the factor also forms heteromers with mammalian retinoic acid and thyroid receptors via a second half-site. It was suggested that the factor functions asa heterodimer in vivo, although its partner or partners have not yet been identified.

Published
1992

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