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Therapeutic apheresis (TA) is prescribed to patients that suffer from a severe progressive disease that is not sufficiently treated by conventional medications. A way to gain more knowledge about this treatment is usually by the local analysis of data. However, the use of large quality assessment registries enables analyses of even rare findings. Here, we report some of the recent data from the World Apheresis Association (WAA) registry. Data from >104,000 procedures were documented, and TA was performed on >15,000 patients. The main indication for TA was the collection of autologous stem cells (45% of patients) as part of therapy for therapy. Collection of stem cells from donors for allogeneic transplantation was performed in 11% of patients. Patients with indications such as neurological diseases underwent plasma exchange (28%). Extracorporeal photochemotherapy, lipid apheresis, and antibody removal were other indications. Side effects recorded in the registry have decreased significantly over the years, with approximately only 10/10,000 procedures being interrupted for medical reasons. Conclusion: Collection of data from TA procedures within a multinational and multicenter concept facilitates the improvement of treatment by enabling the analysis of and feedback on indications, procedures, effects, and side effects.

The aim of this study was to evaluate the safety, tolerability, technical performance and clinical efficacy of a novel adsorptive-type cytapheresis module in patients with active ulcerative colitis. Ten patients with ulcerative colitis (clinical activity index 6-10) were recruited. The new adsorber (Nikkiso, Tokyo, Japan) was specifically designed to remove platelets, granulocytes and monocytes from peripheral blood using an extracorporeal circulation. Cytapheresis treatments were performed weekly for five consecutive weeks (each with a 60-min duration). Safety and tolerability were evaluated by investigating vital parameters, routine laboratory tests, adverse event reporting and a questionnaire. Disease activity was evaluated by assessing the clinical activity index as well as the endoscopic index, according to Rachmilewitz. Technical performance and biocompatibility were investigated by repeated measurements of cellular blood count, complement factor C3a and cell surface markers before, during and after the apheresis treatments. The cytapheresis treatments were "well" to "very well" tolerated by the patients. All measured safety parameters remained essentially unchanged. Performance data showed that platelets, monocytes and neutrophil granulocytes were effectively reduced during the cytapheresis treatments. Apheresis treatment was associated with high remission rates (80% at week 10). Clinical remission was accompanied by the reduction of the endoscopic index in four out of the nine eligible patients. Levels of C3a did not significantly increase during cytapheresis treatments. The novel device has been shown to be safe, well tolerated and clinically efficient. It offered a very good biocompatibility and platelet elimination capacity.

The thermodynamic tabulations previously published as NSRDS‐NBS‐37 are extended by 154 new and revised tables. The JANAF Thermochemical Tables cover the thermodynamic properties over a wide temperature range with single phase tables for the crystal, liquid, and ideal gas state. The properties given are heat capacity, entropy, Gibbs energy function, enthalpy, enthalpy of formation, Gibbs energy of formation, and the logarithm of the equilibrium constant for formation of each compound from the elements in their standard reference states. Each tabulation lists all pertinent input data and contains a critical evaluation of the literature upon which these values are based. Literature references are given.

The thermodynamic tabulations previously published in NSRDS‐NBS‐37 and the 1974 supplement (J. Phys. Chem. Ref. Data 3, 311 [1974]) are extended by 158 new and revised tables. The JANAF Thermochemical Tables cover the thermodynamic properties over a wide temperature range with single phase tables for the crystal, liquid, and ideal gas state. The properties given are heat capacity, entropy, Gibbs energy function, enthalpy, enthalpy of formation, Gibbs energy of formation, and the logarithm of the equilibrium constant for formation of each compound from the elements in their standard reference states. Each tabulation lists all pertinent input data and contains a critical evaluation of the literature upon which these values are based. Literature references are given.

The low temperature heat capacity and far infrared spectra of AlBr 3 (c) have been determined. The results of these measurements are used to assign the vibrational frequencies of Al 2 Br 6 (g) and calculate the thermodynamic functions of AlBr 3 (c), AlBr 3 (l), AlBr 3 (g), and Al 2 Br 6 (g). The entropies, S o (298.15 K), of AlBr 3 (c), AlBr 3 (g), and Al 2 Br 6 (g) are calculated as 43.08, 84.5, and 130.8 cal K −1 mol −1 , respectively. The enthalpy of vaporization, ΔH v o (298.15 K), of AlBr 3 (l) is calculated as 7.81 kcal mol −1 .

Beginning in the mid-1950s, when elements other than the conventional carbon hydrogen, oxygen, nitrogen, chlorine, and fluorine came into consideration as rocket propellant ingredients, formidable difficulties were encountered in conducting rigorous theoretical performance calculations for these new propellants. The first major problem was calculational techniques. The second was the lack of accurate thermodynamic data. By the end of 1959, the calculational technique problem had been substantially resolved by applying the method of minimization of free energy to large, high-speed digital computers. At time point the calculations became as accurate as the thermodynamic data upon which they were based. However, serious gaps were present in the available data. For propellant ingredients, only the standard heat of formation is required to conduct a performance calculation. However, this must be known to a high degree of accuracy. For combustion products, the enthalpy and entropy must be known, as a function of temperature, in addition to the standard heat of formation. In order to resolve the problem, a substantial experimental thermodynamic research program was initiated. Simultaneously, a project was initiated to critically evaluate and compile consistent tables of thermodynamic properties of propellant combustion products for use by the aerospace industry.