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Your search keyword '"Giuseppe Perniciaro"' showing total 5 results
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5 results on '"Giuseppe Perniciaro"'

1. The Role of Sentinel Lymph Node Biopsy in Breast Cancer Patients Who Become Clinically Node-Negative Following Neo-Adjuvant Chemotherapy: A Literature Review

Author

Giulia Ferrarazzo, Alberto Nieri, Emma Firpo, Andrea Rattaro, Alessandro Mignone, Flavio Guasone, Augusto Manzara, Giuseppe Perniciaro, and Stefano Spinaci

Subjects
sentinel lymph node biopsy, breast cancer, neoadjuvant chemotherapy, surgery, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Background: In clinically node-positive (cN+) breast cancer (BC) patients who become clinically node-negative (cN0) following neoadjuvant chemotherapy (NACT), sentinel lymph node biopsy (SLNB) after lymphatic mapping with lymphoscintigraphy is not widely accepted; therefore, it has become a topic of international debate. Objective: Our literature review aims to evaluate the current use of this surgical practice in a clinical setting and focuses on several studies published in the last six years which have contributed to the assessment of the feasibility and accuracy of this practice, highlighting its importance and oncological safety. We have considered the advantages and disadvantages of this technique compared to other suggested methods and strategies. We also evaluated the role of local irradiation therapy after SLNB and state-of-the-art SLN mapping in patients subjected to NACT. Methods: A comprehensive search of PubMed and Cochrane was conducted. All studies published in English from 2018 to August 2023 were evaluated. Results: Breast units are moving towards a de-escalation of axillary surgery, even in the NACT setting. The effects of these procedures on local irradiation are not very clear. Several studies have evaluated the oncological outcome of SLNB procedures. However, none of the alternative techniques proposed to lower the false negative rate (FNR) of SLNB are significant in terms of prognosis. Conclusions: Based on these results, we can state that lymphatic mapping with SLNB in cN+ BC patients who become clinically node-negative (ycN0) following NACT is a safe procedure, with a good prognosis and low axillary failure rates.

Published
2023
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2. Oncoplastic and reconstructive surgery in SENONETWORK Italian breast centers: lights and shadows

Author

Matteo Ghilli, Andrea Vittorio Emanuele Lisa, Marzia Salgarello, Giovanni Papa, Mario Rietjens, Secondo Folli, Annalisa Curcio, Guglielmo Ferrari, Francesco Caruso, Vittorio Altomare, Daniele Friedman, Maria Carmen De Santis, Fiorenza De Rose, Bruno Meduri, Francesca De Felice, Lorenza Marino, Francesca Cucciarelli, Stefania Montemezzi, Pietro Panizza, Paolo Belli, Francesca Caumo, Valeriano Vinci, Giorgio De Santis, Marco Klinger, Manuela Roncella, Francesco Abbonante, Ginevra Lamanna, Augusto Lombardi, Silvio Vischi, Lorenzo Orzalesi, Giovanni Angiolucci, Samantha Bozzo, Laura Pizzorno, Bettina Ballardini, Maggiorino Barbero, Leonardo Barellini, Claudio Battaglia, Luisa Reggiani, Caterina Santi, Nicoletta Biglio, Marina Bortul, Paolo Burelli, Massimo Busani, Roberta Cabula, Katia Cagossi, Vito Maria Fontanarosa, Francesca Catalano, Carla Cedolini, Luigi Ciuffreda, Fabio Corsi, Olindo Custodero, Stefano Mori, Roy De Vita, Loredana Defilippi, Samantha Marcuzzi, Stefano Drago, Giovanni Battista, Loredana Burgoa, Paolo Cristofolini, Giovanna Romanucci, Andrea Loreti, Valerio Prosperi, Paolo Carcoforo, Patrizia Fulvia Franzini, Patrizia Frittelli, Giuseppe Perniciaro, Daniele Generali, Monica Giordano, Giovanazzi Riccardo, Simona Grossi, Alessandra Huscher, Giuseppe La Torre, Gianfranco Lolli, Carla Magni, Stefano Mancini, Lorenzo Galli, Alba Di Leone, Samuele Massarut, Alberto Massocco, Monica Cramarossa, Graziano Meneghini, Luca Fabiocchi, Anna Maria Miglietta, Francesco Millo, Antonella Ciabattoni, Francesca Pellini, Marco Moschetta, Antonino Musolino, Dante Palli, Giulia Pagura, Mariagrazia Pieraccini, Davide Marenco, Romano Polato, Maria Renne, Cosmo Maurizio Ressa, Fabio Ricci, Raffaella Ridolfo, Francesca Angela Rovera, Francesco Barberini, Marina Vinciguerra, Marco Furci, Maria Sciamannini, Daniela Gianquinto, Silvia Petrucci, Angelica Della Valle, Pietra Stancampiano, Andrea Lippi, Giovanni Tazzioli, Davide Lombardi, Martino Trunfio, Luca Valieri, Carlo Vecchio, Paolo Veronesi, and Gretha Grilz

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published
2024
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3. Italian recommendations on enzymatic debridement in burn surgery

Author

Giuseppe Giudice, Mariarosa Romeo, Michelangelo Vestita, Edoardo Caleffi, Rosario Ranno, Paolo Palombo, Catuscia Orlandi, Jasminka Minic, Maurizio Stella, Serena Ciappi, Antonio Di Lonardo, Maurizio Governa, Ilaria Mataro, Giuseppe Perniciaro, Giovanni Alessandro, Davide Melandri, Giulio Maggio, Eliana Pagnozzi, Pasquale Verrienti, Maria Alma Posadinu, Roberto D’Alessio, and Armando De Angelis

Subjects
medicine.medical_specialty, Bromelain (pharmacology), Administration, Topical, medicine.medical_treatment, Burn Units, Delphi method, Scientific literature, Critical Care and Intensive Care Medicine, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Humans, Medicine, business.industry, 030208 emergency & critical care medicine, Burn treatment, General Medicine, Surgery, Debridement, Italy, Debridement (dental), Emergency Medicine, Ready to use, Burns, business
Abstract

Introduction Nexobrid®, a bromelain-based type of enzymatic debridement, has become more prevalent in recent years. We present the recommendations on enzymatic debridement (Nexobrid®)’s role based on the practice knowledge of expert Italian users. Methods The Italian recommendations, endorsed by SIUST (Italian Society of Burn Surgery), on using enzymatic debridement to remove eschars for burn treatment were defined. The definition followed a process to evaluate the level of agreement (a measure of consensus) among selected experts, representing Italian burn centers, concerning defined clinical aspects of enzymatic debridement. The consensus involved a multi-phase process based on the Delphi method. Results The consensus panel included experts from Italy with a combined experience of 1068 burn patients treated with enzymatic debridement. At the end of round 3 of the Delphi method, the panel reached 100% consensus on 26 out of 27 statements. The panel achieved full, strong consensus (all respondents strongly agreed on the statement) on 24 out of 27 statements. Discussion The statements provided by the Italian consensus panel represent a “ready to use” set of recommendations for enzymatic debridement in burn surgery that both draw from and complete the existing scientific literature on the topic. These recommendations are specific to the Italian experience and are neither static nor definitive. As such, they will be updated periodically as further quality evidence becomes available.

Published
2021
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4. The role of enzymatic debridement in burn care in the COVID-19 pandemic. Commentary by the Italian Society of Burn Surgery (SIUST)

Author

Maurizio Stella, Franz Wilhelm Baruffaldi Preis, Davide Melandri, Giovanni Alessandro, Maria Alma Posadinu, Pasquale Verrienti, Giuseppe Giudice, Bruno Azzena, Edoardo Caleffi, Antonio Di Lonardo, Maurizio Governa, Roberto D’Alessio, Paolo Palombo, Giuseppe Perniciaro, Michelangelo Vestita, and Rosario Ranno

Subjects
2019-20 coronavirus outbreak, medicine.medical_specialty, Debridement, Coronavirus disease 2019 (COVID-19), business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), medicine.medical_treatment, Pneumonia, Viral, COVID-19, General Medicine, Critical Care and Intensive Care Medicine, Italy, Pandemic, medicine, Emergency Medicine, Humans, Surgery, Burns, Coronavirus Infections, Intensive care medicine, business, Pandemics
Published
2020
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