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Aim: Comparative analysis of the results of open thrombectomy and conservative therapy in patients with acute thrombosis of the lower limb arteries against the background of the XBB.1.5 ("Kraken") subvariant of Omicron Severe acute respiratory syndrome-related coronavirus-2 (Sars-cov-2). Material and methods: The present prospective, open, multicenter comparative study for the period 04/01/2022 to 12/01/2023 included 167 patients with acute thrombosis of the lower limb arteries against the background of the XBB.1.5 ("Kraken") subvariant of the XBB.1.5 ("Kraken") subvariant of Omicron Sars-cov-2. Depending on the treatment strategy, two groups were formed: group 1 — open thrombectomy (n = 136) and drug treatment with an anticoagulant (unfractionated heparin in a therapeutic dosage) and an antiplatelet (acetylsalicylic acid 125 mg once a day); group 2 — only drug therapy (n = 31). This group consisted of patients who refused surgical revascularization and were on a prophylactic dose of unfractionated heparin (5000 U 3 times a day subcutaneously). On the development of acute arterial thrombosis, 80 U/kg (maximum 5000 U) of unfractionated heparin was injected intravenously in a bolus, followed by transfer to intravenous infusion using an infusion pump with an initial rate of 18 U/kg per hour under control of activated partial thromboplastin time. Analgesic and antiplatelet therapy was also prescribed (acetylsalicylic acid 125 mg once a day). Results: No significant intergroup differences either in mortality rates (group 1: n = 58, 38.2%; group 2: n = 7, 22.6%; p = 0.09) or limb amputation (group 1: n = 63, 46.3%; group 2: n = 9, 29.0%; p = 0.07) were found. However, there was a trend towards a decrease in the incidence of these events in the drug treatment group. After open thrombectomy, rethrombosis developed in 50.7% (n = 69) cases; and thrombosis after rethrombectomy followed by amputation in 46.3% (n = 63). There were no hemorrhagic complications in both groups. Myocardial infarction and ischemic strokes were not recorded. Conclusion: Anticoagulant therapy demonstrates several advantages over aggressive surgical management. However, probably due to the small size of the studied sample, significant differences were not obtained. Further study of this issue is required with the identification of the optimal reperfusion method in this complex cohort of patients. [ABSTRACT FROM AUTHOR]

It has only recently become possible to build the system on a chip (SoC) platform that makes use of field-programmable gate arrays (FPGAs) to moderate the amount of computational load placed on the main processor's CPU core. On the reconfigurable fabric, data used by both the software and the hardware is mapped using optimised memory mapping algorithm that was developed specifically for this purpose. This memory mapping algorithm serves as the base for the entire method. In this work, proposed a novel technique which is optimal energy efficient load aware memory management (ELMM) technique and it concentrated on the amount of extra storage after mapping using task monitoring algorithm and it reduces the energy consumption. The experimental results reveal that the proposed ELMM system of FPGA memory resources can be obtained at a much lower latency with minimal resource overhead and lower power consumption. Implementation of this work can done by using the Xilinx ISE 14.4 simulator and also generated the waveforms. [ABSTRACT FROM AUTHOR]

System-on-Chip (SoC) design is becoming increasingly complex as a result of trends such as miniaturisation and data-intensive applications, and it is becoming increasingly difficult to manage without the use of automated design methods. Prior work proposed a novel technique called optimal energy efficient load aware memory management, which concentrated on the amount of extra storage after mapping using a task monitoring algorithm and reduced the amount of energy consumed. Every shared distributed memory algorithm that has been proposed has been influenced by embedded system synthesis theory. The following are the contributions made by this work to the fields of SoC design in general and on-chip memory optimization in particular. This paper proposes a complete workflow to improve memory subsystems in an application-specific way when the system was designed. In general, the proposed memory optimization methods generate good results in Xilinx's 14.2 integrated simulation environment, when integrated into the complete simulation, optimization, and code generation flow. [ABSTRACT FROM AUTHOR]

Copyright of Anaesthesiologie & Intensivmedizin is the property of DGAI e.V. - Deutsche Gesellschaft fur Anasthesiologie und Intensivmedizin e.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A design of an electrochemical apparatus for separating solutions of chemical and machine-building industries has been developed and the area of membranes in flat channels of flanges has been calculated. It was determined that the increment in the flange membranes area of the apparatus of the developed design in comparison with the prototypes is 16%. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Materials Engineering & Performance is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: One of the most important projects in the post-genome-era is the systemic identification of biological network. The almost of studies for network identification focused on the improvement of computational efficiency in large-scale network inference of complex system with cyclic relations and few attempted have been done for answering practical problem occurred in real biological systems. In this study, we focused to evaluate inferring performance of our previously proposed method for inferring biological network on simple network motifs. Results: We evaluated the network inferring accuracy and efficiency of our previously proposed network inferring algorithm, by using 6 kinds of repeated appearance of highly significant network motifs in the regulatory network of E. coli proposed by Shen-Orr et al and Herrgård et al, and 2 kinds of network motif in S. cerevisiae proposed by Lee et. al. As a result, our method could reconstruct about 40% of interactions in network motif from time-series data set. Moreover the introduction of time-series data of one-factor disrupted model could remarkably improved the performance of network inference. Conclusions: The results of network inference examination of E. coli network motif shows that our network inferring algorithm was able to apply to typical topology of biological network. A continuous examination of inferring well established network motif in biology would strengthen the applicability of our algorithm to the realistic biological network. [ABSTRACT FROM AUTHOR]

Io's tidal volcanoes The extreme geological activity that makes Jupiter's moon Io the most volcanically active body in the Solar System is thought to be the result of tides raised by Jupiter, but it is not known whether the current tidal heat production is sufficiently high to generate the observed surface heat flow. Making use of astrometic observations made between 1891 and 2007, Lainey et al. have estimated the tidal dissipation in Io by tracking its effect on the orbital motions of the Galilean moons. For Io the value is in good agreement with the observed surface heat flow and suggests that Io is close to thermal equilibrium. Dissipation in Jupiter is close to the upper bound of its average value expected from the long-term evolution of the system. The geological activity on Io, volcanically the most active body in the Solar System, is thought to be the result of tides raised by Jupiter, but it is not known whether the current tidal heat production is sufficiently high to generate the observed surface heat flow. Here, a determination of the tidal dissipation in Io and Jupiter is reported; for Io, this is in good agreement with the observed surface heat flow, whereas for Jupiter, dissipation is found to be close to the upper bound of its average value expected from the long-term evolution of the system. Io is the volcanically most active body in the Solar System and has a large surface heat flux.sup.1,2,3. The geological activity is thought to be the result of tides raised by Jupiter.sup.4, but it is not known whether the current tidal heat production is sufficiently high to generate the observed surface heat flow.sup.5,6. Io's tidal heat comes from the orbital energy of the Io-Jupiter system (resulting in orbital acceleration), whereas dissipation of energy in Jupiter causes Io's orbital motion to decelerate. Here we report a determination of the tidal dissipation in Io and Jupiter through its effect on the orbital motions of the Galilean moons. Our results show that the rate of internal energy dissipation in Io (k.sub.2/Q = 0.015 [plus or minus] 0.003, where k.sub.2 is the Love number and Q is the quality factor) is in good agreement with the observed surface heat flow.sup.5,6, and suggest that Io is close to thermal equilibrium. Dissipation in Jupiter (k.sub.2/Q = (1.102 [plus or minus] 0.203) × 10.sup.-5) is close to the upper bound of its average value expected from the long-term evolution of the system.sup.7, and dissipation in extrasolar planets may be higher than presently assumed.sup.8. The measured secular accelerations indicate that Io is evolving inwards, towards Jupiter, and that the three innermost Galilean moons (Io, Europa and Ganymede) are evolving out of the exact Laplace resonance., Author(s): Valéry Lainey [sup.1] , Jean-Eudes Arlot [sup.1] , Ã-zgür Karatekin [sup.2] , Tim Van Hoolst [sup.2] Author Affiliations: (1) IMCCE-Observatoire de Paris, UMR 8028 du CNRS, 77 Avenue Denfert-Rochereau, [...]