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Introduction. Angiosarcomas (ASs) arising from vascular tissue, account for 3.3% of all sarcomas and have a poor prognosis. Radiation-induced AS is a rare late complication of radiotherapy (RT) treatment and is characterized by a gene expression profile such as amplification of the MYC oncogene, by which we can distinguish primary from secondary induced tumor. Case report. For a 77-year-old female patient with early-stage endometrial adenocarcinoma, a radical hysterectomy with bilateral salpingo-oophorectomy was initially done. According to pathological risk factors, the postoperative external beam conformal RT (CRT) of the pelvis was administered with concomitant brachytherapy. Six years after the treatment, on the anterior abdominal wall, in the region of the postoperative irradiation field and surgical scar, an infiltrative AS of the skin and subcutaneous adipose tissue was histologically confirmed. The patient received six cycles of mono-adriamycin chemotherapy with verified partial regression. Additional immunohistochemical analysis (IHC) of c-MYC, Ki67, and CD34 expression showed a high proliferative index (Ki67 around 60%) and c-MYC positivity indicating the molecular pattern of radiation-induced AS. Furthermore, the high proliferative index could explain the positive response to chemotherapy. Conclusion. The novel postoperative RT techniques provide better survival and local control in risk-endometrial cancer groups with a decrease in irradiation complications. These patients with longer survival are at a higher risk of developing radiation-induced tumors as late side-effects of RT. When assessing the probability of radiation-induced AS, IHC analysis of c-MYC expression could distinguish secondary from other AS if Cahan’s criteria are fulfilled.

Accounting frauds, malfeasance, and financial crime are becoming a growingly serious problem. Incorrect financial reports show a false picture of income and financial position of a company. Decisions made by investors and other beneficiaries of financial reports based on false financial information cause immense damage not just to the users of information, but general public as well. Therefore, there is a clear interest of the whole financial public sector that the information presented in financial reports genuinely represents the financial position of a company. Numerous financial frauds from the past and the beginning of this century have seriously disturbed trust of a large number of users of financial information contained in financial reports. In accounting there have always been frauds followed by financial collapses, and lately there have been more frequent frauds and with more serious consequences for us all. Research results on financial frauds show that they can be different, depending on the region, fraud pattern, characteristics of perpetrators and victims who suffer the damage, but the essence remains very similar. The biggest frauds by users of financial reports and investors have been performed by presenting false, i.e. forged financial reports.