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1. $T {-} \mu$ quark matter phase transitions and critical end point in nonlocal PNJL models

Author

Carlomagno, J. P., Ferraris, S. A., Dumm, D. Gómez, and Grunfeld, A. G.

Subjects
High Energy Physics - Phenomenology
Abstract

We study the $T {-} {\mu}$ phase diagram of quark matter under the influence of a strong uniform magnetic field in the framework of a nonlocal extension of the Polyakov Nambu Jona Lasinio model (PNJL). The existence of a critical end point (CEP) is found for the whole considered range of the magnetic field (up to 1 $GeV^{2}$). We analyze the location of this CEP as a function of the external field and discuss the presence of inverse magnetic catalysis for nonzero chemical potentials. Our results show that the temperature of the CEP decreases with the magnetic field, in contrast to the behavior observed in local NJL/PNJL models.

Published
2023

2. Quark matter phase diagram under the influence of strong magnetic fields with a nonlocal chiral model

Author

Carlomagno, J. P., Ferraris, S. A., Dumm, D. Gómez, and Grunfeld, A. G.

Subjects
High Energy Physics - Phenomenology
Abstract

We study the phase diagram in the $T-\mu$ plane for quark matter under the influence of a strong uniform magnetic field $\vec{B}$, in the framework of a non-local extension of the two-flavor Polyakov Nambu-Jona-Lasinio model. We analyze the deconfinement and chiral symmetry restoration transitions in the mean field approximation. For the considered parameterization, it is found that there is always a critical end point (CEP) in the $T-\mu$ plane that separates a first-order transition line from a smooth crossover. The location of the CEP is studied as a function of the magnetic field., Comment: 5 pages, 3 figures

Published
2022
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6. Cold magnetized quark matter at finite density in a nonlocal chiral quark model

Author

Ferraris, S. A., Dumm, D. Gomez, Grunfeld, A. G., and Scoccola, N. N.

Subjects
High Energy Physics - Phenomenology
Abstract

We study the behavior of two-flavor dense quark matter under the influence of an external magnetic field in the framework of a nonlocal chiral quark model with separable interactions. The nonlocality is incorporated in the model by using a Gaussian form factor. It is found that for low and moderate values of magnetic field there is a decrease of the critical chiral restoration chemical potential $\mu_c$, i.e. an inverse magnetic catalysis effect is observed. For larger values of $eB$ the behavior of $\mu_c$ becomes more or less flat, depending on the parametrization. Within the considered parametrization range we do not find a significant growth of the critical chemical potential for large magnetic fields, as occurs in the case of the local NJL model.

Published
2021
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10. Highly magnetized quark matter in the chiral limit.

Author

Ferraris, S. A., Carlomagno, J. P., and Grunfeld, A. G.

Subjects
*QUARK matter, *QUARK-gluon plasma, *MAGNETIC flux density, *CHIRALITY of nuclear particles, *NAMBU-Jona-Lasinio model, *PHASE diagrams
Abstract

We examine the behavior of highly magnetized two‐light‐flavor quark matter within the context of a nonlocal NJL‐type model. This analysis assumes the chiral limit mc=0$$ \left({m}_c=0\right) $$ and incorporates the interaction between fermions and the Polyakov loop. Our calculations utilize a covariant Gaussian form factor. We present phase diagrams on the T−μ$$ T-\mu $$ plane, illustrating different magnetic field strengths. Additionally, we examine the critical endpoint's placement and the de Haas‐Van Alphen transitions within the chiral restored phase, observing their temperature‐dependent characteristics. [ABSTRACT FROM AUTHOR]

Published
2024
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12. COSMOS-Europe: a European network of cosmic-ray neutron soil moisture sensors

Author

Bogena, H.R., Schrön, Martin, Jakobi, J., Ney, P., Zacharias, Steffen, Andreasen, M., Baatz, R., Boorman, D., Duygu, M.B., Eguibar-Galán, M.A., Fersch, B., Franke, T., Geris, J., González Sanchis, M., Kerr, Y., Korf, T., Mengistu, Z., Mialon, A., Nasta, P., Nitychoruk, J., Pisinaras, V., Rasche, D., Rosolem, R., Said, H., Schattan, P., Zreda, M., Achleitner, S., Albentosa-Hernández, E., Akyürek, Z., Blume, T., del Campo, A., Canone, D., Dimitrova-Petrova, K., Evans, J.G., Ferraris, S., Frances, F., Gisolo, D., Güntner, A., Herrmann, F., Iwema, J., Jensen, K.H., Kunstmann, H., Lidón, A., Looms, M.C., Oswald, S., Panagopoulos, A., Patil, A., Power, D., Rebmann, Corinna, Romano, N., Scheiffele, L., Seneviratne, S., Weltin, G., Vereecken, H., Bogena, H.R., Schrön, Martin, Jakobi, J., Ney, P., Zacharias, Steffen, Andreasen, M., Baatz, R., Boorman, D., Duygu, M.B., Eguibar-Galán, M.A., Fersch, B., Franke, T., Geris, J., González Sanchis, M., Kerr, Y., Korf, T., Mengistu, Z., Mialon, A., Nasta, P., Nitychoruk, J., Pisinaras, V., Rasche, D., Rosolem, R., Said, H., Schattan, P., Zreda, M., Achleitner, S., Albentosa-Hernández, E., Akyürek, Z., Blume, T., del Campo, A., Canone, D., Dimitrova-Petrova, K., Evans, J.G., Ferraris, S., Frances, F., Gisolo, D., Güntner, A., Herrmann, F., Iwema, J., Jensen, K.H., Kunstmann, H., Lidón, A., Looms, M.C., Oswald, S., Panagopoulos, A., Patil, A., Power, D., Rebmann, Corinna, Romano, N., Scheiffele, L., Seneviratne, S., Weltin, G., and Vereecken, H.

Abstract

Climate change increases the occurrence and severity of droughts due to increasing temperatures, altered circulation patterns, and reduced snow occurrence. While Europe has suffered from drought events in the last decade unlike ever seen since the beginning of weather recordings, harmonized long-term datasets across the continent are needed to monitor change and support predictions. Here we present soil moisture data from 66 cosmic-ray neutron sensors (CRNSs) in Europe (COSMOS-Europe for short) covering recent drought events. The CRNS sites are distributed across Europe and cover all major land use types and climate zones in Europe. The raw neutron count data from the CRNS stations were provided by 24 research institutions and processed using state-of-the-art methods. The harmonized processing included correction of the raw neutron counts and a harmonized methodology for the conversion into soil moisture based on available in situ information. In addition, the uncertainty estimate is provided with the dataset, information that is particularly useful for remote sensing and modeling applications. This paper presents the current spatiotemporal coverage of CRNS stations in Europe and describes the protocols for data processing from raw measurements to consistent soil moisture products. The data of the presented COSMOS-Europe network open up a manifold of potential applications for environmental research, such as remote sensing data validation, trend analysis, or model assimilation. The dataset could be of particular importance for the analysis of extreme climatic events at the continental scale. Due its timely relevance in the scope of climate change in the recent years, we demonstrate this potential application with a brief analysis on the spatiotemporal soil moisture variability.

Published
2022

16. Endothelial damage in septic shock patients as evidenced by circulating syndecan-1, sphingosine-1-phosphate and soluble VE-cadherin: a substudy of ALBIOS

Author

Piotti, A., Novelli, D., Meessen, J. M. T. A., Ferlicca, D., Coppolecchia, S., Marino, A., Salati, G., Savioli, M., Grasselli, G., Bellani, G., Pesenti, A., Masson, S., Caironi, P., Gattinoni, L., Gobbi, M., Fracasso, C., Latini, R., Bruzzone, P., Pagan, F., Russo, R., Confalonieri, A., Abbruzzese, C., Vergnano, B., Faenza, S., Siniscalchi, A., Pierucci, E., Noto, A., Pezzi, A., Spanu, P., Parrini, V., Oggioni, R., Pasetti, G. S., Casadio, M. C., Buontempo, R., Carrer, S., Piccoli, F., Rizzi, T., Caricato, A., La Sala, M., Antonaci, A., Fassini, P., Paganini, S., Porta, V., Moise, G., Marell, S., Furia, M., Urbano, M. C., Carobbi, R., Poleni, S., Kandil, H., Ballotta, A., Bettini, F., Sanseverino, M., Gatta, A., Cecchini, F., Guatteri, L., Ciceri, G., Raimondi, F., Colombo, R., Ferraris, S., Borelli, M., Bellato, V., Cancellieri, F., Senni, S., Bertocchi, E., Ferri, P., Moioli, G., Fedele, A., Molin, A., Salsi, P., Brunori, E., Elisei, D., Maggio, G., Nicola, F. G., Cavana, M., Morelli, G., Guarino, A., Isetta, M., Tulli, G., Mangani, V., Rossi, N., Ferrari, M., Bona, F., Vay, M., Bartoli, T., Gallo, M., Vettoretto, K., Morte, M. D., Boselli, E., Puscio, D., Bovo, M., Galzerano, A., Carli, M., Zagara, G., Piotti, A, Novelli, D, Meessen, J, Ferlicca, D, Coppolecchia, S, Marino, A, Salati, G, Savioli, M, Grasselli, G, Bellani, G, Pesenti, A, Masson, S, Caironi, P, Gattinoni, L, Gobbi, M, Fracasso, C, and Latini, R

Subjects
Male, Letter, medicine.medical_treatment, 030204 cardiovascular system & hematology, Critical Care and Intensive Care Medicine, Gastroenterology, 0302 clinical medicine, VE-cadherin, Sphingosine, Septic shock, 80 and over, Medicine, Endothelial dysfunction, Phosphorylation, Aged, 80 and over, lcsh:Medical emergencies. Critical care. Intensive care. First aid, Shock, Biomarker, Glycocalyx, Sphingosine-1-phosphate, Syndecan-1, Aged, Antigens, CD, Biomarkers, Cadherins, Endothelium, Female, Humans, Italy, Lysophospholipids, Middle Aged, Retrospective Studies, Shock, Septic, Extravasation, 3. Good health, CD, Endothelial stem cell, medicine.medical_specialty, Sepsis, 03 medical and health sciences, Internal medicine, Albumins, Settore MED/41 - ANESTESIOLOGIA, Renal replacement therapy, Antigens, business.industry, Septic, Research, Albumin, 030208 emergency & critical care medicine, lcsh:RC86-88.9, medicine.disease, business
Abstract

Background Septic shock is characterized by breakdown of the endothelial glycocalyx and endothelial damage, contributing to fluid extravasation, organ failure and death. Albumin has shown benefit in septic shock patients. Our aims were: (1) to identify the relations between circulating levels of syndecan-1 (SYN-1), sphingosine-1-phosphate (S1P) (endothelial glycocalyx), and VE-cadherin (endothelial cell junctions), severity of the disease, and survival; (2) to evaluate the effects of albumin supplementation on endothelial dysfunction in patients with septic shock. Methods This was a retrospective analysis of a multicenter randomized clinical trial on albumin replacement in severe sepsis or septic shock (the Albumin Italian Outcome Sepsis Trial, ALBIOS). Concentrations of SYN-1, S1P, soluble VE-cadherin and other biomarkers were measured on days 1, 2 and 7 in 375 patients with septic shock surviving up to 7 days after randomization. Results Plasma concentrations of SYN-1 and VE-cadherin rose significantly over 7 days. SYN-1 and VE-cadherin were elevated in patients with organ failure, and S1P levels were lower. SYN-1 and VE-cadherin were independently associated with renal replacement therapy requirement during ICU stay, but only SYN-1 predicted its new occurrence. Both SYN-1 and S1P, but not VE-cadherin, predicted incident coagulation failure. Only SYN-1 independently predicted 90-day mortality. Albumin significantly reduced VE-cadherin, by 9.5% (p = 0.003) at all three time points. Conclusion Circulating components of the endothelial glycocalyx and of the endothelial cell junctions provide insights into severity and progression of septic shock, with special focus on incident coagulation and renal failure. Albumin supplementation lowered circulating VE-cadherin consistently over time. Clinical Trial Registration: ALBIOS ClinicalTrials.gov number NCT00707122.

Published
2021

23. PCSK9 is associated with mortality in patients with septic shock: data from the ALBIOS study

Author

Vecchie, A., Bonaventura, A., Meessen, J., Novelli, D., Minetti, S., Elia, E., Ferrara, D., Ansaldo, A. M., Scaravilli, V., Villa, S., Ferla, L., Caironi, P., Latini, R., Carbone, F., Montecucco, F., Bruzzone, P., Pagan, F., Russo, R., Confalonieri, A., Abbruzzese, C., Vergnano, B., Faenza, S., Siniscalchi, A., Pierucci, E., Noto, A., Pezzi, A., Spanu, P., Parrini, V., Oggioni, R., Pasetti, G. S., Casadio, M. C., Buontempo, R., Carrer, S., Piccoli, F., Rizzi, T., Caricato, Anselmo, La Sala, M., Antonaci, A., Fassini, P., Paganini, S., Porta, V., Moise, G., Marell, S., Furia, M., Urbano, M. C., Carobbi, R., Poleni, S., Kandil, H., Ballotta, A., Bettini, F., Sanseverino, M., Gatta, A., Cecchini, F., Guatteri, L., Ciceri, G., Raimondi, F., Colombo, R., Ferraris, S., Borelli, M., Bellato, V., Cancellieri, F., Senni, S., Sacchi, N., Ferri, P., Moioli, G., Fedele, A., Molin, A., Salati, G., Salsi, P., Brunori, E., Elisei, D., Maggio, G., Nicola, F. G., Cavana, M., Morelli, G., Guarino, A., Isetta, M., Tulli, G., Mangani, V., Rossi, N., Ferrari, M., Bona, F., Vay, M., Bartoli, T., Gallo, M., Morte, M. D., Boselli, E., Puscio, D., Galzerano, A., Carli, M., Zagara, G., Caricato A. (ORCID:0000-0001-5929-120X), Vecchie, A., Bonaventura, A., Meessen, J., Novelli, D., Minetti, S., Elia, E., Ferrara, D., Ansaldo, A. M., Scaravilli, V., Villa, S., Ferla, L., Caironi, P., Latini, R., Carbone, F., Montecucco, F., Bruzzone, P., Pagan, F., Russo, R., Confalonieri, A., Abbruzzese, C., Vergnano, B., Faenza, S., Siniscalchi, A., Pierucci, E., Noto, A., Pezzi, A., Spanu, P., Parrini, V., Oggioni, R., Pasetti, G. S., Casadio, M. C., Buontempo, R., Carrer, S., Piccoli, F., Rizzi, T., Caricato, Anselmo, La Sala, M., Antonaci, A., Fassini, P., Paganini, S., Porta, V., Moise, G., Marell, S., Furia, M., Urbano, M. C., Carobbi, R., Poleni, S., Kandil, H., Ballotta, A., Bettini, F., Sanseverino, M., Gatta, A., Cecchini, F., Guatteri, L., Ciceri, G., Raimondi, F., Colombo, R., Ferraris, S., Borelli, M., Bellato, V., Cancellieri, F., Senni, S., Sacchi, N., Ferri, P., Moioli, G., Fedele, A., Molin, A., Salati, G., Salsi, P., Brunori, E., Elisei, D., Maggio, G., Nicola, F. G., Cavana, M., Morelli, G., Guarino, A., Isetta, M., Tulli, G., Mangani, V., Rossi, N., Ferrari, M., Bona, F., Vay, M., Bartoli, T., Gallo, M., Morte, M. D., Boselli, E., Puscio, D., Galzerano, A., Carli, M., Zagara, G., and Caricato A. (ORCID:0000-0001-5929-120X)

Abstract

Background: Pro-protein convertase subtilisin/kexin 9 (PCSK9) is a proenzyme primarily known to regulate low-density lipoprotein receptor re-uptake on hepatocytes. Whether PCSK9 can concurrently trigger inflammation or not remains unclear. Here, we investigated the potential association between circulating levels of PCSK9 and mortality in patients with severe sepsis or septic shock. Methods: Plasma PCSK9 levels at days 1, 2 and 7 were measured in 958 patients with severe sepsis or septic shock previously enrolled in the Albumin Italian Outcome Sepsis (ALBIOS) trial. Correlations between levels of PCSK9 and pentraxin 3 (PTX3), a biomarker of disease severity, were evaluated with ranked Spearman’s coefficients. Cox proportional hazards models were used to assess the association of PCSK9 levels at day 1 with 28- and 90-day mortality. Results: Median plasma PCSK9 levels were 278 [182–452] ng mL−1 on day 1. PCSK9 correlated positively with PTX3 at the three time-points, and patients with septic shock within the first quartile of PCSK9 showed higher levels of PTX3. Similar mortality rates were observed in patients with severe sepsis across PCSK9 quartiles. Patients with septic shock with lower PCSK9 levels on day 1 (within the first quartile) showed the highest 28- and 90-day mortality rate as compared to other quartiles. Conclusion: In our sub-analysis of the ALBIOS trial, we found that patients with septic shock presenting with lower plasma PCSK9 levels experienced higher mortality rate. Further studies are warranted to better evaluate the pathophysiological role of PCSK9 in sepsis.

Published
2020

25. INPPS Flagship: Cluster of Electric Thrusters

Author

Jansen, F., Brandt, T., Dafnis, A., Detsis, E., Ferraris, S., Findlay, J. A. P., Funaki, I., Granjon, R., Grundmann, J. T., Grunwald, G., Guimaraes, L. N. F., Hillebrandt, M., Koroteev, A. S., Kuijper, J. C., Lassoudiere, F., Lovtsov, A. S., Maiwald, V., Masson, F., Muszynski, M., Oriol, S., Richter, M., Schanz, L., Semenkin, A. V., Solodukhin, A. E., Tinsley, T., Tosi, M. C., and Jean-Claude Worms

Subjects
Funktionsleichtbau, 3) INPPS flagship to Mars and Europa, 4) INPPS flagship high power electric thrusters, Controlling, Logistik, 1) DEMOCRITOS and MEGAHIT projects, 5) cluster of high power electric thruster, 6) low power electric thrusters for INPPS co-flying satellite, Autonomie und Fernprogrammierung, Systemanalyse Raumsegment, 2) Nuclear Power Source (NPS)
Abstract

This paper describes the results of the European-Russian DEMOCRITOS and MEGAHIT projects related to the electric thrusters on board the International Nuclear Power and Propulsion System (INPPS) flagship. INPPS flagship is a high power space transportation hybrid tug (power supply primary by nuclear power, by auxiliary solar power ring and chemical propulsion due to subsystems transport for assembly at high Earth orbit above 800 km) for Mars, Europa, Moon and asteroid exploration flights. In dependence from the actual exploration mission, mission phases, trajectory, and preferred international high power electric thrusters (about 20 - 50 kW) with different specific impulse, the results will be discussed in detail - also as a function of the transportable payload mass. Because of the 1 MWe nuclear reactor (successful ground based test confirmed by Russia in 2018) as the power supply for INPPS a cluster of about 15 or more electric thrusters were studied in the DEMOCRITOS project for MARS and EUROPA INPPS flagships. Issues related to power processing units for the electric thrusters were identified and will be discussed. In addition, low power (kW) electric thrusters for an INPPS flagship co-flying small inspection satellite are sketched too. Insofar the presentation is directly highlighting aspects of disruptive electric propulsion subsystems, within the INPPS space system and applied to visionary Mars (including non-human and human) and Europa exploration and space transport tug flights.

Published
2019

30. Twenty-three unsolved problems in hydrology (UPH)–a community perspective

Author

Blöschl, G., Bierkens, M. F. P., Chambel, A., Cudennec, C., Destouni, G., Fiori, A., Kirchner, J. W., McDonnell, J. J., Savenije, H. H. G., Sivapalan, M., Stumpp, C., Toth, E., Volpi, E., Carr, G., Lupton, C., Salinas, J., Széles, B., Viglione, A., Aksoy, H., Allen, S. T., Amin, A., Andréassian, V., Arheimer, B., Aryal, S. K., Baker, V., Bardsley, E., Barendrecht, M. H., Bartosova, A., Batelaan, O., Berghuijs, W. R., Beven, K., Blume, T., Bogaard, T., Borges de Amorim, P., Böttcher, M. E., Boulet, G., Breinl, K., Brilly, M., Brocca, L., Buytaert, W., Castellarin, A., Castelletti, A., Chen, X., Chen, Y., Chifflard, P., Claps, P., Clark, M. P., Collins, A. L., Croke, B., Dathe, A., David, P. C., de Barros, F. P. J., de Rooij, G., Di Baldassarre, G., Driscoll, J. M., Duethmann, D., Dwivedi, R., Eris, E., Farmer, W. H., Feiccabrino, J., Ferguson, G., Ferrari, E., Ferraris, S., Fersch, B., Finger, D., Foglia, L., Fowler, K., Gartsman, B., Gascoin, S., Gaume, E., Gelfan, A., Geris, J., Gharari, S., Gleeson, T., Glendell, M., Gonzalez Bevacqua, A., González-Dugo, M. P., Grimaldi, S., Gupta, A. B., Guse, B., Han, D., Hannah, D., Harpold, A., Haun, S., Heal, K., Helfricht, K., Herrnegger, M., Hipsey, M., Hlaváčiková, H., Hohmann, C., Holko, L., Hopkinson, C., Hrachowitz, M., Illangasekare, T. H., Inam, A., Innocente, C., Istanbulluoglu, E., Jarihani, B., Kalantari, Z., Kalvans, A., Khanal, S., Khatami, S., Kiesel, J., Kirkby, M., Knoben, W., Kochanek, K., Kohnová, S., Kolechkina, A., Krause, S., Kreamer, D., Kreibich, H., Kunstmann, H., Lange, H., Liberato, M. L. R., Lindquist, E., Link, T., Liu, J., Loucks, D. P., Luce, C., Mahé, G., Makarieva, O., Malard, J., Mashtayeva, S., Maskey, S., Mas-Pla, J., Mavrova-Guirguinova, M., Mazzoleni, M., Mernild, S., Misstear, B. D., Montanari, A., Müller-Thomy, H., Nabizadeh, A., Nardi, F., Neale, C., Nesterova, N., Nurtaev, B., Odongo, V. O., Panda, S., Pande, S., Pang, Z., Papacharalampous, G., Perrin, C., Pfister, L., Pimentel, R., Polo, M. J., Post, D., Prieto Sierra, C., Ramos, M. -H, Renner, M., Reynolds, J. E., Ridolfi, E., Rigon, R., Riva, M., Robertson, D. E., Rosso, R., Roy, T., Sá, J.H.M., Salvadori, G., Sandells, M., Schaefli, B., Schumann, A., Scolobig, A., Seibert, J., Servat, E., Shafiei, M., Sharma, A., Sidibe, M., Sidle, R. C., Skaugen, T., Smith, H., Spiessl, S. M., Stein, L., Steinsland, I., Strasser, U., Su, B., Szolgay, J., Tarboton, D., Tauro, F., Thirel, G., Tian, F., Tong, R., Tussupova, K., Tyralis, H., Uijlenhoet, R., van Beek, R., van der Ent, R. J., van der Ploeg, M., Van Loon, A. F., van Meerveld, I., van Nooijen, R., van Oel, P. R., Vidal, J. -P, von Freyberg, J., Vorogushyn, S., Wachniew, P., Wade, A. J., Ward, P., Westerberg, I. K., White, C., Wood, E. F., Woods, R., Xu, Z., Yilmaz, K. K., Zhang, Y., Blöschl, G., Bierkens, M. F. P., Chambel, A., Cudennec, C., Destouni, G., Fiori, A., Kirchner, J. W., McDonnell, J. J., Savenije, H. H. G., Sivapalan, M., Stumpp, C., Toth, E., Volpi, E., Carr, G., Lupton, C., Salinas, J., Széles, B., Viglione, A., Aksoy, H., Allen, S. T., Amin, A., Andréassian, V., Arheimer, B., Aryal, S. K., Baker, V., Bardsley, E., Barendrecht, M. H., Bartosova, A., Batelaan, O., Berghuijs, W. R., Beven, K., Blume, T., Bogaard, T., Borges de Amorim, P., Böttcher, M. E., Boulet, G., Breinl, K., Brilly, M., Brocca, L., Buytaert, W., Castellarin, A., Castelletti, A., Chen, X., Chen, Y., Chifflard, P., Claps, P., Clark, M. P., Collins, A. L., Croke, B., Dathe, A., David, P. C., de Barros, F. P. J., de Rooij, G., Di Baldassarre, G., Driscoll, J. M., Duethmann, D., Dwivedi, R., Eris, E., Farmer, W. H., Feiccabrino, J., Ferguson, G., Ferrari, E., Ferraris, S., Fersch, B., Finger, D., Foglia, L., Fowler, K., Gartsman, B., Gascoin, S., Gaume, E., Gelfan, A., Geris, J., Gharari, S., Gleeson, T., Glendell, M., Gonzalez Bevacqua, A., González-Dugo, M. P., Grimaldi, S., Gupta, A. B., Guse, B., Han, D., Hannah, D., Harpold, A., Haun, S., Heal, K., Helfricht, K., Herrnegger, M., Hipsey, M., Hlaváčiková, H., Hohmann, C., Holko, L., Hopkinson, C., Hrachowitz, M., Illangasekare, T. H., Inam, A., Innocente, C., Istanbulluoglu, E., Jarihani, B., Kalantari, Z., Kalvans, A., Khanal, S., Khatami, S., Kiesel, J., Kirkby, M., Knoben, W., Kochanek, K., Kohnová, S., Kolechkina, A., Krause, S., Kreamer, D., Kreibich, H., Kunstmann, H., Lange, H., Liberato, M. L. R., Lindquist, E., Link, T., Liu, J., Loucks, D. P., Luce, C., Mahé, G., Makarieva, O., Malard, J., Mashtayeva, S., Maskey, S., Mas-Pla, J., Mavrova-Guirguinova, M., Mazzoleni, M., Mernild, S., Misstear, B. D., Montanari, A., Müller-Thomy, H., Nabizadeh, A., Nardi, F., Neale, C., Nesterova, N., Nurtaev, B., Odongo, V. O., Panda, S., Pande, S., Pang, Z., Papacharalampous, G., Perrin, C., Pfister, L., Pimentel, R., Polo, M. J., Post, D., Prieto Sierra, C., Ramos, M. -H, Renner, M., Reynolds, J. E., Ridolfi, E., Rigon, R., Riva, M., Robertson, D. E., Rosso, R., Roy, T., Sá, J.H.M., Salvadori, G., Sandells, M., Schaefli, B., Schumann, A., Scolobig, A., Seibert, J., Servat, E., Shafiei, M., Sharma, A., Sidibe, M., Sidle, R. C., Skaugen, T., Smith, H., Spiessl, S. M., Stein, L., Steinsland, I., Strasser, U., Su, B., Szolgay, J., Tarboton, D., Tauro, F., Thirel, G., Tian, F., Tong, R., Tussupova, K., Tyralis, H., Uijlenhoet, R., van Beek, R., van der Ent, R. J., van der Ploeg, M., Van Loon, A. F., van Meerveld, I., van Nooijen, R., van Oel, P. R., Vidal, J. -P, von Freyberg, J., Vorogushyn, S., Wachniew, P., Wade, A. J., Ward, P., Westerberg, I. K., White, C., Wood, E. F., Woods, R., Xu, Z., Yilmaz, K. K., and Zhang, Y.

Abstract

QC 20210112

Published
2019
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31. Twenty-three unsolved problems in hydrology (UPH)–a community perspective

Author

Blöschl, G. Bierkens, M. F. P. Chambel, A. Cudennec, C. Destouni, G. Fiori, A. Kirchner, J. W. McDonnell, J. J. Savenije, H. H. G. Sivapalan, M. Stumpp, C. Toth, E. Volpi, E. Carr, G. Lupton, C. Salinas, J. Széles, B. Viglione, A. Aksoy, H. Allen, S. T. Amin, A. Andréassian, V. Arheimer, B. Aryal, S. K. Baker, V. Bardsley, E. Barendrecht, M. H. Bartosova, A. Batelaan, O. Berghuijs, W. R. Beven, K. Blume, T. Bogaard, T. Borges de Amorim, P. Böttcher, M. E. Boulet, G. Breinl, K. Brilly, M. Brocca, L. Buytaert, W. Castellarin, A. Castelletti, A. Chen, X. Chen, Y. Chen, Y. Chifflard, P. Claps, P. Clark, M. P. Collins, A. L. Croke, B. Dathe, A. David, P. C. de Barros, F. P. J. de Rooij, G. Di Baldassarre, G. Driscoll, J. M. Duethmann, D. Dwivedi, R. Eris, E. Farmer, W. H. Feiccabrino, J. Ferguson, G. Ferrari, E. Ferraris, S. Fersch, B. Finger, D. Foglia, L. Fowler, K. Gartsman, B. Gascoin, S. Gaume, E. Gelfan, A. Geris, J. Gharari, S. Gleeson, T. Glendell, M. Gonzalez Bevacqua, A. González-Dugo, M. P. Grimaldi, S. Gupta, A. B. Guse, B. Han, D. Hannah, D. Harpold, A. Haun, S. Heal, K. Helfricht, K. Herrnegger, M. Hipsey, M. Hlaváčiková, H. Hohmann, C. Holko, L. Hopkinson, C. Hrachowitz, M. Illangasekare, T. H. Inam, A. Innocente, C. Istanbulluoglu, E. Jarihani, B. Kalantari, Z. Kalvans, A. Khanal, S. Khatami, S. Kiesel, J. Kirkby, M. Knoben, W. Kochanek, K. Kohnová, S. Kolechkina, A. Krause, S. Kreamer, D. Kreibich, H. Kunstmann, H. Lange, H. Liberato, M. L. R. Lindquist, E. Link, T. Liu, J. Loucks, D. P. Luce, C. Mahé, G. Makarieva, O. Malard, J. Mashtayeva, S. Maskey, S. Mas-Pla, J. Mavrova-Guirguinova, M. Mazzoleni, M. Mernild, S. Misstear, B. D. Montanari, A. Müller-Thomy, H. Nabizadeh, A. Nardi, F. Neale, C. Nesterova, N. Nurtaev, B. Odongo, V. O. Panda, S. Pande, S. Pang, Z. Papacharalampous, G. Perrin, C. Pfister, L. Pimentel, R. Polo, M. J. Post, D. Prieto Sierra, C. Ramos, M. H. Renner, M. Reynolds, J. E. Ridolfi, E. Rigon, R. Riva, M. Robertson, D. E. Rosso, R. and Blöschl, G. Bierkens, M. F. P. Chambel, A. Cudennec, C. Destouni, G. Fiori, A. Kirchner, J. W. McDonnell, J. J. Savenije, H. H. G. Sivapalan, M. Stumpp, C. Toth, E. Volpi, E. Carr, G. Lupton, C. Salinas, J. Széles, B. Viglione, A. Aksoy, H. Allen, S. T. Amin, A. Andréassian, V. Arheimer, B. Aryal, S. K. Baker, V. Bardsley, E. Barendrecht, M. H. Bartosova, A. Batelaan, O. Berghuijs, W. R. Beven, K. Blume, T. Bogaard, T. Borges de Amorim, P. Böttcher, M. E. Boulet, G. Breinl, K. Brilly, M. Brocca, L. Buytaert, W. Castellarin, A. Castelletti, A. Chen, X. Chen, Y. Chen, Y. Chifflard, P. Claps, P. Clark, M. P. Collins, A. L. Croke, B. Dathe, A. David, P. C. de Barros, F. P. J. de Rooij, G. Di Baldassarre, G. Driscoll, J. M. Duethmann, D. Dwivedi, R. Eris, E. Farmer, W. H. Feiccabrino, J. Ferguson, G. Ferrari, E. Ferraris, S. Fersch, B. Finger, D. Foglia, L. Fowler, K. Gartsman, B. Gascoin, S. Gaume, E. Gelfan, A. Geris, J. Gharari, S. Gleeson, T. Glendell, M. Gonzalez Bevacqua, A. González-Dugo, M. P. Grimaldi, S. Gupta, A. B. Guse, B. Han, D. Hannah, D. Harpold, A. Haun, S. Heal, K. Helfricht, K. Herrnegger, M. Hipsey, M. Hlaváčiková, H. Hohmann, C. Holko, L. Hopkinson, C. Hrachowitz, M. Illangasekare, T. H. Inam, A. Innocente, C. Istanbulluoglu, E. Jarihani, B. Kalantari, Z. Kalvans, A. Khanal, S. Khatami, S. Kiesel, J. Kirkby, M. Knoben, W. Kochanek, K. Kohnová, S. Kolechkina, A. Krause, S. Kreamer, D. Kreibich, H. Kunstmann, H. Lange, H. Liberato, M. L. R. Lindquist, E. Link, T. Liu, J. Loucks, D. P. Luce, C. Mahé, G. Makarieva, O. Malard, J. Mashtayeva, S. Maskey, S. Mas-Pla, J. Mavrova-Guirguinova, M. Mazzoleni, M. Mernild, S. Misstear, B. D. Montanari, A. Müller-Thomy, H. Nabizadeh, A. Nardi, F. Neale, C. Nesterova, N. Nurtaev, B. Odongo, V. O. Panda, S. Pande, S. Pang, Z. Papacharalampous, G. Perrin, C. Pfister, L. Pimentel, R. Polo, M. J. Post, D. Prieto Sierra, C. Ramos, M. H. Renner, M. Reynolds, J. E. Ridolfi, E. Rigon, R. Riva, M. Robertson, D. E. Rosso, R.

Abstract

This paper is the outcome of a community initiative to identify major unsolved scientific problems in hydrology motivated by a need for stronger harmonisation of research efforts. The procedure involved a public consultation through online media, followed by two workshops through which a large number of potential science questions were collated, prioritised, and synthesised. In spite of the diversity of the participants (230 scientists in total), the process revealed much about community priorities and the state of our science: a preference for continuity in research questions rather than radical departures or redirections from past and current work. Questions remain focused on the process-based understanding of hydrological variability and causality at all space and time scales. Increased attention to environmental change drives a new emphasis on understanding how change propagates across interfaces within the hydrological system and across disciplinary boundaries. In particular, the expansion of the human footprint raises a new set of questions related to human interactions with nature and water cycle feedbacks in the context of complex water management problems. We hope that this reflection and synthesis of the 23 unsolved problems in hydrology will help guide research efforts for some years to come.

Published
2019
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32. Anthropometric characteristics of newborns with Prader-Willi syndrome

Author

Salvatoni, A, Moretti, A, Grugni, G, Agosti, M, Azzolini, S, Bonaita, V, Cianci, P, Corica, D, Crinò, A, Delvecchio, M, Ferraris, S, Greggio, N, Iughetti, L, Licenziati, M, Madeo, S, Nosetti, L, Pajno, R, Rutigliano, I, Sacco, M, Salvatore, S, Scarano, E, Trifirò, G, Wasniewska, M, Salvatoni, Alessandro, Moretti, Alex, Grugni, Graziano, Agosti, Massimo, Azzolini, Sara, Bonaita, Valentina, Cianci, Paola, Corica, Domenico, Crinò, Antonino, Delvecchio, Maurizio, Ferraris, Silvio, Greggio, Nella A, Iughetti, Lorenzo, Licenziati, Maria R, Madeo, Simona F, Nosetti, Luana, Pajno, Roberta, Rutigliano, Irene, Sacco, Michele, Salvatore, Silvia, Scarano, Emanuela, Trifirò, Giuliana, Wasniewska, Malgorzata, Salvatoni, A, Moretti, A, Grugni, G, Agosti, M, Azzolini, S, Bonaita, V, Cianci, P, Corica, D, Crinò, A, Delvecchio, M, Ferraris, S, Greggio, N, Iughetti, L, Licenziati, M, Madeo, S, Nosetti, L, Pajno, R, Rutigliano, I, Sacco, M, Salvatore, S, Scarano, E, Trifirò, G, Wasniewska, M, Salvatoni, Alessandro, Moretti, Alex, Grugni, Graziano, Agosti, Massimo, Azzolini, Sara, Bonaita, Valentina, Cianci, Paola, Corica, Domenico, Crinò, Antonino, Delvecchio, Maurizio, Ferraris, Silvio, Greggio, Nella A, Iughetti, Lorenzo, Licenziati, Maria R, Madeo, Simona F, Nosetti, Luana, Pajno, Roberta, Rutigliano, Irene, Sacco, Michele, Salvatore, Silvia, Scarano, Emanuela, Trifirò, Giuliana, and Wasniewska, Malgorzata

Abstract

This is a retrospective multicenter nationwide Italian study collecting neonatal anthropometric data of Caucasian subjects with Prader–Willi syndrome (PWS) born from 1988 to 2018. The aim of the study is to provide percentile charts for weight and length of singletons with PWS born between 36 and 42 gestational weeks. We collected the birth weight and birth length of 252 male and 244 female singleton live born infants with both parents of Italian origin and PWS genetically confirmed. Percentile smoothed curves of birth weight and length for gestational age were built through Cole's lambda, mu, sigma method. The data were compared to normal Italian standards. Newborns with PWS showed a lower mean birth weight, by 1/2 kg, and a shorter mean birth length, by 1 cm, than healthy neonates. Females with a 15q11-13 deletion were shorter than those with maternal uniparental maternal disomy of chromosome 15 (p <.0001). The present growth curves may be useful as further traits in supporting a suspicion of PWS in a newborn. Because impaired prenatal growth increases risk of health problems later in life, having neonatal anthropometric standards could be helpful to evaluate possible correlations between the presence or absence of small gestational age and some clinical and metabolic aspects of PWS.

Published
2019

36. The effect of microbial activity on soil water diffusivity

Author

Choudhury, B. U., Ferraris, S., Ashton, R. W., Powlson, D. S., and Whalley, W. R.

Subjects
Soil Science
Abstract

In this study, we explored the effects of microbial activity on the evaporation of water from cores of a sandy soil under laboratory conditions. We applied treatments to stimulate microbial activity by adding different amounts of synthetic analogue root exudates. For comparison, we used soil samples without synthetic root exudates as control and samples treated with mercuric chloride to suppress microbial activity. Our results suggest that increasing microbial activity reduces the rate of evaporation from soil. Estimated diffusivities in soil with the largest amounts of added root exudates were one third of those estimated in samples where microbial activity was suppressed by adding mercuric chloride. We discuss the effect of our results with respect to water uptake by roots.

Published
2018

40. A study on the combined effects of evapotranspiration and redistribution

Author

Environmental Sciences, Spatial Ecology and Global Change, Raffelli, Giulia, Baudena, M., Canone, Davide, Gisolo, Davide, Ferraris, S., Environmental Sciences, Spatial Ecology and Global Change, Raffelli, Giulia, Baudena, M., Canone, Davide, Gisolo, Davide, and Ferraris, S.

Published
2018

42. Trends of some high quantiles of average and extremes inter-arrival timesand rainfall depths at daily scale for an Italian Sub-Alpine area

Author

Ferraris, S, Agnese, C, Canone, D, Previati, M, Cat Berro, D, Mercalli, L., BAIAMONTE, Giorgio, Ferraris, S, Agnese, C, Baiamonte, G, Canone, D, Previati, M, Cat Berro, D, and Mercalli, L

Subjects
Settore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-Forestali, Trend, inter-arrivale times, rainfall depths
Abstract

Modeling of rainfall statistical structure represents an important research area in hydrology, meteorology, atmospheric physics and climatology, because of the several theoretical and practical implications. The statistical inference of the alternation of wet periods (WP) and dry periods (DP) in daily rainfall records can be achieved through the modelling of inter-arrival time-series (IT), defined as the succession of times elapsed from a rainy day and the one immediately preceding it. It has been shown previously that the statistical structure of IT can be well described by the 3-parameter Lerch distribution (Lch). In this work, Lch was successfully applied to IT data belonging to a sub-alpine area (Piemonte and Valle d’Aosta, NW Italy); furthermore the same statistical procedure was applied to daily rainfall records to ITs associated. The analysis has been carried out for 26 daily rainfall long-series ( 90 yr of observations). The main objective of this work was to detect temporal trends of some features describing the statistical structure of both inter-arrival time-series (IT) and associated rainfall depth (H). Each time-series was divided on subsets of five years long and for each of them the estimation of the Lch parameter was performed, so to extend the trend analysis to some high quantiles.

Published
2015

43. Antibacterial silver nanocluster/silica composite coatings on stainless steel

Author

Ferraris, M., Perero, S., Ferraris, S., Miola, M., Verne, E., Skoglund, Sara, Blomberg, Eva, Odnevall Wallinder, Inger, Ferraris, M., Perero, S., Ferraris, S., Miola, M., Verne, E., Skoglund, Sara, Blomberg, Eva, and Odnevall Wallinder, Inger

Abstract

A coating made of silver nanocluster/silica composites has been deposited, Via a radio frequency (RF) co-sputtering technique, for the first time onto stainless steel (AISI 304L) with the aim to improve its antibacterial properties. Different thermal treatments after coating deposition have been applied in order to optimize the coating adhesion, cohesion and its antibacterial properties. Its applicability has been investigated at realistic conditions in a cheese production plant. The physico-chemical characteristics of the coatings have been analyzed by means of different bulk and surface analytical techniques. Field emission scanning electron microscopy (FESEM), X-ray Photoelectron Spectroscopy (XPS), contact angle measurements and atomic force microscopy (AFM) were employed to assess coating morphology, composition, surface roughness, wetting properties, size and local distribution of the nanoparticles within the coating. Tape tests were used to determine the adhesion/cohesion properties of the coating. The amount and time-dependence of released silver in solutions of acetic acid, artificial water, artificial tap water and artificial milk were determined by means of Atomic Absorption Spectroscopy (AAS). The antibacterial effect of the coating was evaluated at different experimental conditions using a standard bacterial strain of Staphylococcus aureus in compliance with National Committee for Clinical Laboratory Standards (NCCLS) and AATCC 147 standards. The Ahearn test was performed to measure the adhesion of bacteria to the coated stainless steel surface compared with a control surface. The antibacterial coating retained its antibacterial activity after thermal treatment up to 450 degrees C and after soaking in common cleaning products for stainless steel surfaces used for e.g. food applications. The antibacterial capacity of the coating remained at high levels for 1-5 days, and showed a good capacity to reduce the adhesion of bacteria up to 30 days. Only a few p, QC 20170210

Published
2017
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46. Albumin replacement in patients with severe sepsis or septic shock

Author

Gattinoni L, Caironi P, Pesenti A, Fumagalli R, Tognoni G, Romero M, Latini R, Masson S, Vincent JL, Suter PM, Valsecchi MG, Santosuosso A, Cavana M, Ortu A, Gabini R, Perno S, Anelli A, Amoruso R, Ferraris S, Borelli M, Massei R, Riva I, Poli G, Papagni G, Bortone F, Mamprin F, Keim R, Brivio M, Colageo U, Mimii EP, Sangiorgi G, Siniscalchi A, Pierucci E, Giovannitti A, Gentile C, Pascucci F, Antonini B, Zummo U, Valsecchi R, Cerisara M, Trezzi T, Dossena A, Ribola A, Tamayo L, Zoppellari R, Volta CA, Mangani V, Fanfani E, Chelazzi C, Bartoli T, Parrini V, Oggioni R, Fedele A, Molin A, Berri C, Guarino A, Isetta M, Bonfiglio M, Tissino F, Silvestri L, Milanesi M, Sbrana G, Motta E, Iannaco I, Casadio MC, Pasetti GS, Palandini A, Cascione C, Puscio D, Cellai F, Boccalatte D, Silvestri S, Fausto CI, Lupo V, Zompanti V, Iacobone E, Gattari D, Ronzoni G, Beck E, Francesconi S, Colombo R, Raimondi F, Castelli A, De Gasperi A, Radrizzani D, Ferla LE, Giudici R, Bellato V, Bordone G, Gavazzeni V, Lesmo A, Ripamonti D, Vesconi S, Papoff A, Rossi A, Noto A, Pezzi A, Zanforlin G, Kandil H, Ballotta A, Bettini F, Vaghi GM, Rossi S, Pessina C, Casagrande D, Trivellato A, Costagli V, Moise G, Furla M, Marelli S, Caspani L, Panigada M, Bruzzone P, Isgrò S, Abbruzzese C, Tagliabue P, Solca M, Bonazzi M, Cattaneo A, Rossi N, Andreoni P, Pasetto A, Girardis M, Barbieri E, Piazza O, Zagara G, Bono M, Galzerano A, Garzilli T, Dentini N, Bindi M, Biancofiore G, Mercante WP, Disconzi MM, Todesco N, Lunardi S, Sani E, Carli M, Bracciotti G, Gori V, Braccini P, Maggio G, Braschi A, Bottazzi A, Iotti G, Nicora B, Salati G, Salsi P, Antonelli M, Pennisi MA, Bello G, Caccese R, D'Ambrosio M, Rocco M, Sanseverino M, Gatta A, Nastasi M, Corsi A, Facondini F, Franchi F, Mongelli P, Ferrario M, Carulli F, Del Curto S, Schiappacasse G, Dalpiaz C, Armani S, Verderosa I, Marzullo A, Tonetti F, De Piero ME, Livigni S, Fiore G, Cerutti A, Erbetta S, Napolitano R, Pastorelli M, Bona F, Debernardi F, Gallo M, Segala V, Parigi L, Perzolla D, Marson F, Chiarandini P, Cammarano C, Sermann G, De Lucia S, Frigerio A, Distaso F, Franco R, Bossi E, Laudi C, De Nardin M, Violo T, Lazzari F, Vestali A, Della Mora E, Polati E, Martini A, Cristallini S, Totaro C, Milan B, Dan M, Ruberti S, Danzi V., GIARRATANO, Antonino, RAINERI, Santi Maurizio, CORTEGIANI, Andrea, Caironi, P, Tognoni, G, Masson, S, Fumagalli, R, Pesenti, A, Romero, M, Fanizza, C, Caspani, L, Faenza, S, Grasselli, G, Iapichino, G, Antonelli, M, Parrini, V, Fiore, G, Latini, R, Gattinoni, L, Caironi P, Tognoni G, Masson S, Fumagalli R, Pesenti A, Romero M, Fanizza C, Caspani L, Faenza S, Grasselli G, Iapichino G, Antonelli M, Parrini V, Fiore G, Latini R, Gattinoni L, Vincent JL, Suter PM, Valsecchi MG, Santosuosso A, Cavana M, Ortu A, Gabini R, Perno S, Anelli A, Amoruso R, Ferraris S, Borelli M, Massei R, Riva I, Poli G, Papagni G, Bortone F, Mamprin F, Keim R, Brivio M, Colageo U, Mimii EP, Sangiorgi G, Siniscalchi A, Pierucci E, Giovannitti A, Gentile C, Pascucci F, Antonini B, Zummo U, Valsecchi R, Cerisara M, Trezzi T, Dossena A, Ribola A, Tamayo L, Zoppellari R, Volta CA, Mangani V, Fanfani E, Chelazzi C, Bartoli T, Oggioni R, Fedele A, Molin A, Berri C, Guarino A, Isetta M, Bonfiglio M, Tissino F, Silvestri L, Milanesi M, Sbrana G, Motta E, Iannaco I, Casadio MC, Pasetti GS, Palandini A, Cascione C, Puscio D, Cellai F, Boccalatte D, Silvestri S, Fausto CI, Lupo V, Zompanti V, Iacobone E, Gattari D, Ronzoni G, Beck E, Francesconi S, Colombo R, Raimondi F, Castelli A, De Gasperi A, Radrizzani D, Ferla LE, Giudici R, Bellato V, Bordone G, Gavazzeni V, Lesmo A, Ripamonti D, Vesconi S, Papoff A, Rossi A, Noto A, Pezzi A, Zanforlin G, Kandil H, Ballotta A, Bettini F, Vaghi GM, Rossi S, Pessina C, Casagrande D, Trivellato A, Costagli V, Moise G, Furla M, Marelli S, Panigada M, Bruzzone P, Isgrò S, Abbruzzese C, Tagliabue P, Solca M, Bonazzi M, Cattaneo A, Rossi N, Andreoni P, Pasetto A, Girardis M, Barbieri E, Piazza O, Giarratano A, Raineri SM, Cortegiani A, Zagara G, Bono M, Galzerano A, Garzilli T, Dentini N, Bindi M, Biancofiore G, Mercante WP, Disconzi MM, Todesco N, Lunardi S, Sani E, Carli M, Bracciotti G, Gori V, Braccini P, Maggio G, Braschi A, Bottazzi A, Iotti G, Nicora B, Salati G, Salsi P, Pennisi MA, Bello G, Caccese R, D'Ambrosio M, Rocco M, Sanseverino M, Gatta A, Nastasi M, Corsi A, Facondini F, Franchi F, Mongelli P, Ferrario M, Carulli F, Del Curto S, Schiappacasse G, Dalpiaz C, Armani S, Verderosa I, Marzullo A, Tonetti F, De Piero ME, Livigni S, Cerutti A, Erbetta S, Napolitano R, Pastorelli M, Bona F, Debernardi F, Gallo M, Segala V, Parigi L, Perzolla D, Marson F, Chiarandini P, Cammarano C, Sermann G, De Lucia S, Frigerio A, Distaso F, Franco R, Bossi E, Laudi C, De Nardin M, Violo T, Lazzari F, Vestali A, Della Mora E, Polati E, Martini A, Cristallini S, Totaro C, Milan B, Dan M, Ruberti S, and Danzi V

Subjects
Male, medicine.medical_specialty, ALBUMIN, SEPSIS, SEVERE SEPSIS, SEPTIC SHOCK, Sepsi, Serum albumin, Settore MED/41 - Anestesiologia, Aged, Albumins, Female, Humans, Isotonic Solutions, Middle Aged, Rehydration Solutions, Sepsis, Serum Albumin, Shock, Septic, Survival Rate, Treatment Outcome, Intensive care, medicine, albumin replacement, Survival rate, Isotonic Solution, Medicine (all), SEPSIS, biology, business.industry, Septic shock, Rehydration Solution, Septic, Albumin, SEPTIC SHOCK, Organ dysfunction, Shock, General Medicine, medicine.disease, Surgery, Anesthesia, Relative risk, biology.protein, medicine.symptom, business, Human
Abstract

BACKGROUND: Although previous studies have suggested the potential advantages of albumin administration in patients with severe sepsis, its efficacy has not been fully established. METHODS: In this multicenter, open-label trial, we randomly assigned 1818 patients with severe sepsis, in 100 intensive care units (ICUs), to receive either 20% albumin and crystalloid solution or crystalloid solution alone. In the albumin group, the target serum albumin concentration was 30 g per liter or more until discharge from the ICU or 28 days after randomization. The primary outcome was death from any cause at 28 days. Secondary outcomes were death from any cause at 90 days, the number of patients with organ dysfunction and the degree of dysfunction, and length of stay in the ICU and the hospital. RESULTS: During the first 7 days, patients in the albumin group, as compared with those in the crystalloid group, had a higher mean arterial pressure (P = 0.03) and lower net fluid balance (P

Published
2014

47. Applying a probabilistic model of rainfall and snow days occurrence to daily series recorded in NW Italy

Author

Ferraris, S, Cat Berro, D, Mercalli, L, Canone, D, Previati, M., AGNESE, Carmelo, BAIAMONTE, Giorgio, CAMMALLERI, Carmelo, Ferraris, S, Agnese, C, Baiamonte, G, Cammalleri, C, Cat Berro, D, Mercalli, L, Canone, D, and Previati, M

Subjects
Hurwitz–Lerch Zeta probability distributions, Inter-arrival times, Rain probability, Settore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-Forestali
Abstract

Daily precipitation records exist spanning several decades. A valuable amount of climatic information exists in the time-series of interarrival times (IT), defined as the succession of times (number of days) elapsed from a rainy (or snowy) day to the one immediately preceding it.In a previous work, Agnese et al. (2014) have been successfully tested some probabilistic modelling of rain occurrence on Sicily rainfall data; particularly, the better fitting of IT’s observed frequencies was obtained by 3-parameter Lerch-series distribution. In this work thisdistribution is tested on 70 years of 20 precipitation time-series taken in the North-West Italy, both in the plain and in the mountains, up to the 2000 meters altitude. In such Mediterranean climatetwo markedly different behaviours were observed in the dry semester (April to September) and in the wet one (October to March). A better fit was obtained with that simple subdivision of the year, in comparison with the whole year modelling. However, the NW Italy climate is both more similar to the Central Europe one, and it is deeply influenced by the higher peaks of the Alps. Therefore the seasonality of daily precipitation data is much more complicated. Usually spring and fall are the seasons characterized by the higher precipitations, but the convective vs. frontal events also play a role in the IT distributions. In this work, different subdivisions were compared with the whole year fitting. The whole year Lerch distributions successfully fitted the data in a part of the time series, opening the way to interesting climate applications.

Published
2014

48. Assessing Tn5 and Sleeping Beauty for transpositional transgenesis by cytoplasmic injection into bovine and ovine zygotes

Author

Bevacqua, R. J., primary, Fernandez-Martin, R., additional, Canel, N. G., additional, Gibbons, A., additional, Texeira, D., additional, Lange, F., additional, Vans Landschoot, G., additional, Savy, V., additional, Briski, O., additional, Hiriart, M. I., additional, Grueso, E., additional, Ivics, Z., additional, Taboga, O., additional, Kues, W. A., additional, Ferraris, S., additional, and Salamone, D. F., additional

Published
2017
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