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2. Perspektiven der Sozialen Landwirtschaft unter besonderer Berücksichtigung der Entwicklungen in Italien

Author

Angeli, Sergio, Benedetti, Anna, Bernhard, Armin, Biasia, Livio, Busch, Gesa, Dalla Torre, Cristina, Elsen, Susanne, Ferrari, Mauro, Gauly, Matthias, Genova, Angela, Gramm, Verena, Kiesswetter, Oscar, Lintner, Claudia, Musolino, Dario, Nicli, Sara, Nothdurfter, Urban, Rottensteiner, Anna, Simionato, Tommaso, van Elsen, Thomas, Viganò, Federica, Wiesinger, Georg, Bernhard, Armin, Nicli, Sara, Elsen, Susanne, and Angeli, Sergio

Subjects
Italy, Social Agriculture, Italien, Soziale Landwirtschaft, Italia, Agricoltura sociale, bic Book Industry Communication::T Technology, engineering, agriculture::TV Agriculture & farming, bic Book Industry Communication::T Technology, engineering, agriculture::TV Agriculture & farming::TVG Organic farming, bic Book Industry Communication::J Society & social sciences::JK Social services & welfare, criminology::JKS Social welfare & social services
Abstract

This volume presents the current scientific debate, innovative projects and approaches of Social Agriculture in Italy and in the German-speaking area. The work is aimed at professionals from social services, health and education, students of social sciences and agricultural economics, and those responsible for social policies, regional development, organic farming and eco-social transformation.; Diese Publikation stellt aktuelle wissenschaftliche Diskurse, innovative Projekte und Konzepte der Sozialen Landwirtschaft in Italien und im deutschsprachigen Raum vor. Sie richtet sich an Fachkräfte des Sozial,- Gesundheits- und Bildungswesens, Studierende des Sozialwesens und der Agrarwirtschaft, Verantwortliche der Sozialpolitik und Regionalentwicklung, der biologischen Landwirtschaft und der öko-sozialen Transformation. ; Questo volume presenta l’attuale dibattito scientifico, progetti innovativi e approcci dell’Agricoltura Sociale in Italia e nell’area germanofona. Il lavoro si rivolge a professionisti dei servizi sociali, della sanità e dell’istruzione, a studenti delle scienze sociali e di economia agraria e ai responsabili delle politiche sociali, dello sviluppo regionale, dell’agricoltura biologica e della trasformazione eco-sociale.

Published
2020
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4. SAT-Based Proof Search in Intermediate Propositional Logics

Author

Fiorentini, Camillo, Ferrari, Mauro, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Blanchette, Jasmin, editor, Kovács, Laura, editor, and Pattinson, Dirk, editor

Published
2022
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5. Duality between unprovability and provability in forward proof-search for Intuitionistic Propositional Logic

Author

Fiorentini, Camillo and Ferrari, Mauro

Subjects
Mathematics - Logic, Computer Science - Logic in Computer Science
Abstract

The inverse method is a saturation based theorem proving technique; it relies on a forward proof-search strategy and can be applied to cut-free calculi enjoying the subformula property. Here we apply this method to derive the unprovability of a goal formula G in Intuitionistic Propositional Logic. To this aim we design a forward calculus FRJ(G) for Intuitionistic unprovability which is prone to constructively ascertain the unprovability of a formula G by providing a concise countermodel for it; in particular we prove that the generated countermodels have minimal height. Moreover, we clarify the role of the saturated database obtained as result of a failed proof-search in FRJ(G) by showing how to extract from such a database a derivation witnessing the Intuitionistic validity of the goal.

Published
2018
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6. Publisher Correction: On the issue of transparency and reproducibility in nanomedicine

Author

Leong, Hon S, Butler, Kimberly S, Brinker, C Jeffrey, Azzawi, May, Conlan, Steve, Dufès, Christine, Owen, Andrew, Rannard, Steve, Scott, Chris, Chen, Chunying, Dobrovolskaia, Marina A, Kozlov, Serguei V, Prina-Mello, Adriele, Schmid, Ruth, Wick, Peter, Caputo, Fanny, Boisseau, Patrick, Crist, Rachael M, McNeil, Scott E, Fadeel, Bengt, Tran, Lang, Hansen, Steffen Foss, Hartmann, Nanna B, Clausen, Lauge PW, Skjolding, Lars M, Baun, Anders, Ågerstrand, Marlene, Gu, Zhen, Lamprou, Dimitrios A, Hoskins, Clare, Huang, Leaf, Song, Wantong, Cao, Huiliang, Liu, Xuanyong, Jandt, Klaus D, Jiang, Wen, Kim, Betty YS, Wheeler, Korin E, Chetwynd, Andrew J, Lynch, Iseult, Moghimi, Seyed Moein, Nel, André, Xia, Tian, Weiss, Paul S, Sarmento, Bruno, das Neves, José, Santos, Hélder A, Santos, Luis, Mitragotri, Samir, Little, Steve, Peer, Dan, Amiji, Mansoor M, Alonso, Maria José, Petri-Fink, Alke, Balog, Sandor, Lee, Aaron, Drasler, Barbara, Rothen-Rutishauser, Barbara, Wilhelm, Stefan, Acar, Handan, Harrison, Roger G, Mao, Chuanbin, Mukherjee, Priyabrata, Ramesh, Rajagopal, McNally, Lacey R, Busatto, Sara, Wolfram, Joy, Bergese, Paolo, Ferrari, Mauro, Fang, Ronnie H, Zhang, Liangfang, Zheng, Jie, Peng, Chuanqi, Du, Bujie, Yu, Mengxiao, Charron, Danielle M, Zheng, Gang, and Pastore, Chiara

Subjects
Nanoscience & Nanotechnology
Abstract

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Published
2019

9. Long-term results of treatment of infrarenal aortic aneurysms with low-profile stent grafts in a multicenter registry

Author

Righini, Paolo, Fino, Gianluigi, Orrico, Matteo, Ronchey, Sonia, Sirignano, Pasqualino, Berchiolli, Raffaella, Chisci, Emiliano, Tadiello, Marco, Galzerano, Giuseppe, Mele, Mariagnese, Ferraro, Greta, de Donato, Gianmarco, Pasqui, Edoardo, Nano, Giovanni, Lenti, Massimo, Mangialardi, Nicola, Speziale, Francesco, Ferrari, Mauro, Michelagnoli, Stefano, Tozzi, Matteo, and Palasciano, Giancarlo

Published
2022
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11. Insight from an Italian Delphi Consensus on EVAR feasibility outside the instruction for use: the SAFE EVAR Study

Author

Sirignano, P, Piffaretti, G, Ceruti, S, Orso, M, Picozzi, M, Ricci, G, Sirignano, A, Taurino, M, Giancarlo Accarino, M, Accrocca, F, Alba, G, Alberti, A, Alberti, V, Allevi, S, Aloisi, F, Amato, B, Amico, A, Andreoli, F, Angiletta, D, Antico, A, Antico, L, Antonello, M, Baccellieri, D, Badalamenti, G, Bafile, G, Baldi, C, Barillà, C, Barillà, D, Bartoli, S, Basile, G, Battaglia, G, Battocchio, C, Belloni, A, Bellosta, R, Benevento, D, Bernardini, G, Bertagna, G, Bertoglio, L, Bianchini Massoni, C, Bisacco, D, Bischetti, M, Boccalon, L, Bonanno, P, Bonardelli, S, Borioni, R, P Borrelli, M, Bozzani, A, M Bracale, U, Camparini, S, Canciglia, A, Canova, F, Capoccia, L, Cappelli, A, Cappiello, P, Carluccio, C, Casalino, A, Casella, F, Casilli, G, Castagno, C, Castelli, P, Castrucci, T, Cavallo, M, Cavazzini, C, Ceccanei, G, Cefalì, P, Celoria, G, Cevolani, M, Chiappa, R, Chisci, E, Comande, C, Compagna, R, Cumino, A, Cuozzo, S, Dalla Caneva, P, D'Alessio, I, D'Arrigo, G, DE Caridi, G, DE Donato, G, DE Donno, G, Desantis, C, DE Santis, F, DE Troia, A, Dezi, T, A Diaco, D, DI Domenico, R, DI Filippo, M, DI Girolamo, A, P Dionisi, C, Dinoto, E, DI Stefano, F, DI STEFANO, L, D'Oria, M, Esposito, A, Esposito, D, Ettore, L, F Fadda, G, Faggioli, G, T Fargion, A, Fazzini, S, Fermani, N, Ferrante, G, Ferrari, M, Ferraro, S, Ferrer, C, Ferretto, L, Ficarelli, I, Filippi, F, Fino, G, Forliti, E, Formiconi, M, Flora, L, Fresilli, M, Frigatti, P, Frigerio, D, Froio, A, Freyrie, A, Furgiuele, S, Gabrielli, R, Gaggiano, A, Galassi, L, Gallelli, G, Gallitto, E, Gallo, F, Galzerano, G, Gargiulo, M, Garriboli, L, G Genadiev, G, Gentile, L, Giaquinta, A, Gibello, L, Grande, R, Grassi, V, Ippoliti, A, Irsara, S, Kahlberg, A, Konstantinos, N, LA Corte, F, Lanza, G, Lauricella, A, Lazzeri, E, Lenti, M, Leopardi, M, Lepidi, S, Li Destri, A, Locatelli, F, Lomazzi, C, Lombardi, F, Lorido, A, Maggiore, C, Mansour, W, Marcucci, V, Mascia, D, Massara, M, Mastrangelo, G, Margheritini, C, Maritati, G, Martelli, E, Martinelli, O, Marzano, A, Mauri, F, Mazzacaro, D, Melloni, A, Mezzetti, R, Michelagnoli, S, Migliara, B, Migliari, M, Millarelli, M, Misuraca, M, Modugno, P, Moniaci, D, Montelione, N, Monti, A, Monzio-Compagnoni, N, Moro, M, Mortola, L, Mozzetta, G, Musilli, A, Nano, G, Occhiuto, M, M Oddi, F, Orellana, B, Orlando, P, Orrico, M, A Pacilè, M, Pagliariccio, G, Pallini, C, Palmieri, A, Palughi, M, Panagrasso, M, Panzano, C, Panzera, C, Pascucci, F, Pasqua, R, Pasquetti, L, Pasqui, E, Pecchio, A, Pecoraro, F, Peluttiero, I, F Pennetta, F, Perini, P, Piazza, M, Pini, R, Pipito, N, Pranteda, C, Praquin, B, Pratesi, C, F Porreca, C, Pulli, R, Reina, N, F Rinaldi, L, Rizzo, L, Romano, E, Ronchey, S, Ruggiero, F, Ruggiero, M, Sallustro, M, Saviane, G, Sbarigia, E, Scovazzi, P, M Segramor, V, Sena, G, Setacci, C, Setacci, F, E Setteducati, C, M Settembrini, A, Siani, A, Sica, S, Speziale, F, Squizzato, F, Stella, N, Stilo, F, Sufali, G, Tanda, E, Tinelli, G, Tomei, F, Tosti, F, Trimarchi, S, Troisi, N, Tshomba, Y, Turchino, D, Turriziani, V, Ucci, A, Veneto, V, Veraldi, G, Wiesel, P, Xodo, A, Zacà, S, Zaraca, F, Zenunaj, G, SIRIGNANO, Pasqualino, PIFFARETTI, Gabriele, CERUTI, Silvia, ORSO, Massimiliano, PICOZZI, Mario, RICCI, Giovanna, SIRIGNANO, Ascanio, TAURINO, Maurizio, Giancarlo Accarino, Maurizio, Accrocca, Federico, Alba, Giuseppe, Alberti, Antonino, Alberti, Vittorio, Allevi, Sara, Aloisi, Francesco, Amato, Bruno, Amico, Alessio, Andreoli, Francesco, Angiletta, Domenico, Antico, Antonio, Antico, Lorenzo, Antonello, Michele, Baccellieri, Domenico, Badalamenti, Giovanni, Bafile, Gennaro, Baldi, Claudio, Barillà, Chiara, Barillà, David, Bartoli, Stefano, Basile, Giusi, Battaglia, Giuseppe, Battocchio, Cesare, Belloni, Ailin, Bellosta, Raffello, Benevento, Domenico, Bernardini, Giulia, Bertagna, Giulia, Bertoglio, Luca, Bianchini Massoni, Claudio, Bisacco, Daniel, Bischetti, Michelangelo, Boccalon, Luca, Bonanno, Paolo, Bonardelli, Stefano, Borioni, Raul, P Borrelli, Maria, Bozzani, Antonio, M Bracale, Umberto, Camparini, Stefano, Canciglia, Aldo, Canova, Francesco, Capoccia, Laura, Cappelli, Alessandro, Cappiello, Pierlugi, Carluccio, Chiara, Casalino, Alfonso, Casella, Francesco, Casilli, Giulia, Castagno, Claudio, Castelli, Patrizio, Castrucci, Tommaso, Cavallo, Matteo, Cavazzini, Carlo, Ceccanei, Gianluca, Cefalì, Pietro, Celoria, Gianni, Cevolani, Mauro, Chiappa, Roberto, Chisci, Emiliano, Comande, Carlo, Compagna, Rita, Cumino, Andrea, Cuozzo, Simone, Dalla Caneva, Patrizia, D'Alessio, Ilaria, D'Arrigo, Giuseppe, DE Caridi, Giovanni, DE Donato, Gianmarco, DE Donno, Gabriele, Desantis, Claudio, DE Santis, Francesco, DE Troia, Alessandro, Dezi, Tommaso, A Diaco, Domenico, DI Domenico, Rossella, DI Filippo, Michele, DI Girolamo, Alessia, P Dionisi, Carlo, Dinoto, Ettore, DI Stefano, Francesco, DI STEFANO, Lucia, D'Oria, Mario, Esposito, Andrea, Esposito, Davide, Ettore, Ludovica, F Fadda, Gian, Faggioli, Gianluca, T Fargion, Aaron, Fazzini, Stefano, Fermani, Nicoletta, Ferrante, Giulia, Ferrari, Mauro, Ferraro, Stafanio, Ferrer, Ciro, Ferretto, Luca, Ficarelli, Ilaria, Filippi, Federico, Fino, Gianluigi, Forliti, Enzo, Formiconi, Martina, Flora, Loris, Fresilli, Mauro, Frigatti, Paolo, Frigerio, Dalmazio, Froio, Alberto, Freyrie, Antonio, Furgiuele, Sergio, Gabrielli, Roberto, Gaggiano, Andrea, Galassi, Luca, Gallelli, Giuseppe, Gallitto, Enrico, Gallo, Francesco, Galzerano, Giuseppe, Gargiulo, Mauro, Garriboli, Luca, G Genadiev, Genadi, Gentile, Lucia, Giaquinta, Alessia, Gibello, Lorenzo, Grande, Raffaele, Grassi, Viviana, Ippoliti, Arnaldo, Irsara, Sandro, Kahlberg, Andrea, Konstantinos, Nikolakopoulos, LA Corte, Francesco, Lanza, Gaetano, Lauricella, Antonio, Lazzeri, Elisa, Lenti, Massimo, Leopardi, Marco, Lepidi, Sandro, Li Destri, Andrea, Locatelli, Federica, Lomazzi, Chiara, Lombardi, Francesco, Lorido, Antonio, Maggiore, Claudia, Mansour, Wassim, Marcucci, Vittorio, Mascia, Daniele, Massara, Mafalda, Mastrangelo, Giovanni, Margheritini, Costanza, Maritati, Gabriele, Martelli, Eugenio, Martinelli, Ombretta, Marzano, Antonio, Mauri, Francesca, Mazzacaro, Daniela, Melloni, Andrea, Mezzetti, Roberto, Michelagnoli, Stefano, Migliara, Bruno, Migliari, Mattia, Millarelli, Massimiliano, Misuraca, Maria, Modugno, Pietro, Moniaci, Diego, Montelione, Nunzio, Monti, Andrea, Monzio-Compagnoni, Nicola, Moro, Mario, Mortola, Lorenzo, Mozzetta, Gaddiel, Musilli, Aldo, Nano, Giovanni, Occhiuto, Mariateresa, M Oddi, Fabio, Orellana, Bernardo, Orlando, Paola, Orrico, Matteo, A Pacilè, Maria, Pagliariccio, Gabriele, Pallini, Cristina, Palmieri, Armando, Palughi, Martina, Panagrasso, Marco, Panzano, Claudia, Panzera, Chiara, Pascucci, Francesco, Pasqua, Rocco, Pasquetti, Leonardo, Pasqui, Eduardo, Pecchio, Alberto, Pecoraro, Felice, Peluttiero, Ilaria, F Pennetta, Federico, Perini, Paolo, Piazza, Michele, Pini, Rodolfo, Pipito, Narayana, Pranteda, Chiara, Praquin, Barbara, Pratesi, Carlo, F Porreca, Carlo, Pulli, Raffaele, Reina, Nicola, F Rinaldi, Luigi, Rizzo, Luigi, Romano, Elisa, Ronchey, Sonia, Ruggiero, Federica, Ruggiero, Massimo, Sallustro, Marianna, Saviane, Gianna, Sbarigia, Enrico, Scovazzi, Paolo, M Segramor, Vittorio, Sena, Giuseppe, Setacci, Carlo, Setacci, Francesco, E Setteducati, Carmen, M Settembrini, Alberto, Siani, Andrea, Sica, Simona, Speziale, Francesco, Squizzato, Francesco, Stella, Nazzareno, Stilo, Francesco, Sufali, Gemmi, Tanda, Elisabetta, Tinelli, Giovanni, Tomei, Francesca, Tosti, Filomena, Trimarchi, Santi, Troisi, Nicola, Tshomba, Yamume, Turchino, Davide, Turriziani, Valerio, Ucci, Alessandro, Veneto, Vincenzo, Veraldi, Gianfranco, Wiesel, Paola, Xodo, Andrea, Zacà, Sergio, Zaraca, Francesco, Zenunaj, Glaudiol, Sirignano, P, Piffaretti, G, Ceruti, S, Orso, M, Picozzi, M, Ricci, G, Sirignano, A, Taurino, M, Giancarlo Accarino, M, Accrocca, F, Alba, G, Alberti, A, Alberti, V, Allevi, S, Aloisi, F, Amato, B, Amico, A, Andreoli, F, Angiletta, D, Antico, A, Antico, L, Antonello, M, Baccellieri, D, Badalamenti, G, Bafile, G, Baldi, C, Barillà, C, Barillà, D, Bartoli, S, Basile, G, Battaglia, G, Battocchio, C, Belloni, A, Bellosta, R, Benevento, D, Bernardini, G, Bertagna, G, Bertoglio, L, Bianchini Massoni, C, Bisacco, D, Bischetti, M, Boccalon, L, Bonanno, P, Bonardelli, S, Borioni, R, P Borrelli, M, Bozzani, A, M Bracale, U, Camparini, S, Canciglia, A, Canova, F, Capoccia, L, Cappelli, A, Cappiello, P, Carluccio, C, Casalino, A, Casella, F, Casilli, G, Castagno, C, Castelli, P, Castrucci, T, Cavallo, M, Cavazzini, C, Ceccanei, G, Cefalì, P, Celoria, G, Cevolani, M, Chiappa, R, Chisci, E, Comande, C, Compagna, R, Cumino, A, Cuozzo, S, Dalla Caneva, P, D'Alessio, I, D'Arrigo, G, DE Caridi, G, DE Donato, G, DE Donno, G, Desantis, C, DE Santis, F, DE Troia, A, Dezi, T, A Diaco, D, DI Domenico, R, DI Filippo, M, DI Girolamo, A, P Dionisi, C, Dinoto, E, DI Stefano, F, DI STEFANO, L, D'Oria, M, Esposito, A, Esposito, D, Ettore, L, F Fadda, G, Faggioli, G, T Fargion, A, Fazzini, S, Fermani, N, Ferrante, G, Ferrari, M, Ferraro, S, Ferrer, C, Ferretto, L, Ficarelli, I, Filippi, F, Fino, G, Forliti, E, Formiconi, M, Flora, L, Fresilli, M, Frigatti, P, Frigerio, D, Froio, A, Freyrie, A, Furgiuele, S, Gabrielli, R, Gaggiano, A, Galassi, L, Gallelli, G, Gallitto, E, Gallo, F, Galzerano, G, Gargiulo, M, Garriboli, L, G Genadiev, G, Gentile, L, Giaquinta, A, Gibello, L, Grande, R, Grassi, V, Ippoliti, A, Irsara, S, Kahlberg, A, Konstantinos, N, LA Corte, F, Lanza, G, Lauricella, A, Lazzeri, E, Lenti, M, Leopardi, M, Lepidi, S, Li Destri, A, Locatelli, F, Lomazzi, C, Lombardi, F, Lorido, A, Maggiore, C, Mansour, W, Marcucci, V, Mascia, D, Massara, M, Mastrangelo, G, Margheritini, C, Maritati, G, Martelli, E, Martinelli, O, Marzano, A, Mauri, F, Mazzacaro, D, Melloni, A, Mezzetti, R, Michelagnoli, S, Migliara, B, Migliari, M, Millarelli, M, Misuraca, M, Modugno, P, Moniaci, D, Montelione, N, Monti, A, Monzio-Compagnoni, N, Moro, M, Mortola, L, Mozzetta, G, Musilli, A, Nano, G, Occhiuto, M, M Oddi, F, Orellana, B, Orlando, P, Orrico, M, A Pacilè, M, Pagliariccio, G, Pallini, C, Palmieri, A, Palughi, M, Panagrasso, M, Panzano, C, Panzera, C, Pascucci, F, Pasqua, R, Pasquetti, L, Pasqui, E, Pecchio, A, Pecoraro, F, Peluttiero, I, F Pennetta, F, Perini, P, Piazza, M, Pini, R, Pipito, N, Pranteda, C, Praquin, B, Pratesi, C, F Porreca, C, Pulli, R, Reina, N, F Rinaldi, L, Rizzo, L, Romano, E, Ronchey, S, Ruggiero, F, Ruggiero, M, Sallustro, M, Saviane, G, Sbarigia, E, Scovazzi, P, M Segramor, V, Sena, G, Setacci, C, Setacci, F, E Setteducati, C, M Settembrini, A, Siani, A, Sica, S, Speziale, F, Squizzato, F, Stella, N, Stilo, F, Sufali, G, Tanda, E, Tinelli, G, Tomei, F, Tosti, F, Trimarchi, S, Troisi, N, Tshomba, Y, Turchino, D, Turriziani, V, Ucci, A, Veneto, V, Veraldi, G, Wiesel, P, Xodo, A, Zacà, S, Zaraca, F, Zenunaj, G, SIRIGNANO, Pasqualino, PIFFARETTI, Gabriele, CERUTI, Silvia, ORSO, Massimiliano, PICOZZI, Mario, RICCI, Giovanna, SIRIGNANO, Ascanio, TAURINO, Maurizio, Giancarlo Accarino, Maurizio, Accrocca, Federico, Alba, Giuseppe, Alberti, Antonino, Alberti, Vittorio, Allevi, Sara, Aloisi, Francesco, Amato, Bruno, Amico, Alessio, Andreoli, Francesco, Angiletta, Domenico, Antico, Antonio, Antico, Lorenzo, Antonello, Michele, Baccellieri, Domenico, Badalamenti, Giovanni, Bafile, Gennaro, Baldi, Claudio, Barillà, Chiara, Barillà, David, Bartoli, Stefano, Basile, Giusi, Battaglia, Giuseppe, Battocchio, Cesare, Belloni, Ailin, Bellosta, Raffello, Benevento, Domenico, Bernardini, Giulia, Bertagna, Giulia, Bertoglio, Luca, Bianchini Massoni, Claudio, Bisacco, Daniel, Bischetti, Michelangelo, Boccalon, Luca, Bonanno, Paolo, Bonardelli, Stefano, Borioni, Raul, P Borrelli, Maria, Bozzani, Antonio, M Bracale, Umberto, Camparini, Stefano, Canciglia, Aldo, Canova, Francesco, Capoccia, Laura, Cappelli, Alessandro, Cappiello, Pierlugi, Carluccio, Chiara, Casalino, Alfonso, Casella, Francesco, Casilli, Giulia, Castagno, Claudio, Castelli, Patrizio, Castrucci, Tommaso, Cavallo, Matteo, Cavazzini, Carlo, Ceccanei, Gianluca, Cefalì, Pietro, Celoria, Gianni, Cevolani, Mauro, Chiappa, Roberto, Chisci, Emiliano, Comande, Carlo, Compagna, Rita, Cumino, Andrea, Cuozzo, Simone, Dalla Caneva, Patrizia, D'Alessio, Ilaria, D'Arrigo, Giuseppe, DE Caridi, Giovanni, DE Donato, Gianmarco, DE Donno, Gabriele, Desantis, Claudio, DE Santis, Francesco, DE Troia, Alessandro, Dezi, Tommaso, A Diaco, Domenico, DI Domenico, Rossella, DI Filippo, Michele, DI Girolamo, Alessia, P Dionisi, Carlo, Dinoto, Ettore, DI Stefano, Francesco, DI STEFANO, Lucia, D'Oria, Mario, Esposito, Andrea, Esposito, Davide, Ettore, Ludovica, F Fadda, Gian, Faggioli, Gianluca, T Fargion, Aaron, Fazzini, Stefano, Fermani, Nicoletta, Ferrante, Giulia, Ferrari, Mauro, Ferraro, Stafanio, Ferrer, Ciro, Ferretto, Luca, Ficarelli, Ilaria, Filippi, Federico, Fino, Gianluigi, Forliti, Enzo, Formiconi, Martina, Flora, Loris, Fresilli, Mauro, Frigatti, Paolo, Frigerio, Dalmazio, Froio, Alberto, Freyrie, Antonio, Furgiuele, Sergio, Gabrielli, Roberto, Gaggiano, Andrea, Galassi, Luca, Gallelli, Giuseppe, Gallitto, Enrico, Gallo, Francesco, Galzerano, Giuseppe, Gargiulo, Mauro, Garriboli, Luca, G Genadiev, Genadi, Gentile, Lucia, Giaquinta, Alessia, Gibello, Lorenzo, Grande, Raffaele, Grassi, Viviana, Ippoliti, Arnaldo, Irsara, Sandro, Kahlberg, Andrea, Konstantinos, Nikolakopoulos, LA Corte, Francesco, Lanza, Gaetano, Lauricella, Antonio, Lazzeri, Elisa, Lenti, Massimo, Leopardi, Marco, Lepidi, Sandro, Li Destri, Andrea, Locatelli, Federica, Lomazzi, Chiara, Lombardi, Francesco, Lorido, Antonio, Maggiore, Claudia, Mansour, Wassim, Marcucci, Vittorio, Mascia, Daniele, Massara, Mafalda, Mastrangelo, Giovanni, Margheritini, Costanza, Maritati, Gabriele, Martelli, Eugenio, Martinelli, Ombretta, Marzano, Antonio, Mauri, Francesca, Mazzacaro, Daniela, Melloni, Andrea, Mezzetti, Roberto, Michelagnoli, Stefano, Migliara, Bruno, Migliari, Mattia, Millarelli, Massimiliano, Misuraca, Maria, Modugno, Pietro, Moniaci, Diego, Montelione, Nunzio, Monti, Andrea, Monzio-Compagnoni, Nicola, Moro, Mario, Mortola, Lorenzo, Mozzetta, Gaddiel, Musilli, Aldo, Nano, Giovanni, Occhiuto, Mariateresa, M Oddi, Fabio, Orellana, Bernardo, Orlando, Paola, Orrico, Matteo, A Pacilè, Maria, Pagliariccio, Gabriele, Pallini, Cristina, Palmieri, Armando, Palughi, Martina, Panagrasso, Marco, Panzano, Claudia, Panzera, Chiara, Pascucci, Francesco, Pasqua, Rocco, Pasquetti, Leonardo, Pasqui, Eduardo, Pecchio, Alberto, Pecoraro, Felice, Peluttiero, Ilaria, F Pennetta, Federico, Perini, Paolo, Piazza, Michele, Pini, Rodolfo, Pipito, Narayana, Pranteda, Chiara, Praquin, Barbara, Pratesi, Carlo, F Porreca, Carlo, Pulli, Raffaele, Reina, Nicola, F Rinaldi, Luigi, Rizzo, Luigi, Romano, Elisa, Ronchey, Sonia, Ruggiero, Federica, Ruggiero, Massimo, Sallustro, Marianna, Saviane, Gianna, Sbarigia, Enrico, Scovazzi, Paolo, M Segramor, Vittorio, Sena, Giuseppe, Setacci, Carlo, Setacci, Francesco, E Setteducati, Carmen, M Settembrini, Alberto, Siani, Andrea, Sica, Simona, Speziale, Francesco, Squizzato, Francesco, Stella, Nazzareno, Stilo, Francesco, Sufali, Gemmi, Tanda, Elisabetta, Tinelli, Giovanni, Tomei, Francesca, Tosti, Filomena, Trimarchi, Santi, Troisi, Nicola, Tshomba, Yamume, Turchino, Davide, Turriziani, Valerio, Ucci, Alessandro, Veneto, Vincenzo, Veraldi, Gianfranco, Wiesel, Paola, Xodo, Andrea, Zacà, Sergio, Zaraca, Francesco, and Zenunaj, Glaudiol

Abstract

BACKGROUND: The SAfety and FEasibility of standard EVAR outside the instruction for use (SAFE-EVAR) Study was designed to define the attitude of Italian vascular surgeons towards the use of standard endovascular repair (EVAR) for infrarenal abdominal aortic aneurysm (AAA) outside the instruction for use (IFU) through a Delphi consensus endorsed by the Italian Society of Vascular and Endovascular Surgery (Societa Italiana di Chirurgia Vascolare ed Endovascolare - SICVE). METHODS: A questionnaire consisting of 26 statements was developed, validated by an 18 -member Advisory Board, and then sent to 600 Italian vascular surgeons. The Delphi process was structured in three subsequent rounds which took place between April and June 2023. In the first two rounds, respondents could indicate one of the following five degrees of agreement: 1) strongly agree; 2) partially agree; 3) neither agree nor disagree; 4) partially disagree; 5) strongly disagree; while in the third round only three different choices were proposed: 1) agree; 2) neither agree nor disagree; 3) disagree. We considered the consensus reached when >70% of respondents agreed on one of the options. After the conclusion of each round, a report describing the percentage distribution of the answers was sent to all the participants. RESULTS: Two -hundred -forty-four (40.6%) Italian Vascular Surgeons agreed to participate the first round of the Delphi Consensus; the second and the third rounds of the Delphi collected 230 responders (94.3% of the first -round responders). Four statements (15.4%) reached a consensus in the first rounds. Among the 22 remaining statements, one more consensus (3.8%) was achieved in the second round. Finally, seven more statements (26.9%) reached a consensus in the simplified last round. Globally, a consensus was reached for almost half of the proposed statements (46.1%). CONCLUSIONS: The relatively low consensus rate obtained in this Delphi seems to confirm the discrepancy between Guide

Published
2024

13. A Note on Semantic Web Services Specification and Composition in Constructive Description Logics

Author

Bozzato, Loris and Ferrari, Mauro

Subjects
Computer Science - Artificial Intelligence, Computer Science - Logic in Computer Science, I.2.4, F.4.1, H.3.5
Abstract

The idea of the Semantic Web is to annotate Web content and services with computer interpretable descriptions with the aim to automatize many tasks currently performed by human users. In the context of Web services, one of the most interesting tasks is their composition. In this paper we formalize this problem in the framework of a constructive description logic. In particular we propose a declarative service specification language and a calculus for service composition. We show by means of an example how this calculus can be used to define composed Web services and we discuss the problem of automatic service synthesis., Comment: 15 pages, 2 figures. Part of this work will appear as a position paper in Proceedings of 4th Int. Conf. on Web Reasoning and Rule Systems (RR 2010)

Published
2010

15. Tumor lysing genetically engineered T cells loaded with multi-modal imaging agents.

Author

Bhatnagar, Parijat, Alauddin, Mian, Bankson, James A, Kirui, Dickson, Seifi, Payam, Huls, Helen, Lee, Dean A, Babakhani, Aydin, Ferrari, Mauro, Li, King C, and Cooper, Laurence JN

Subjects
T-Lymphocytes, Humans, Receptors, Antigen, T-Cell, Recombinant Fusion Proteins, Antigens, CD19, Contrast Media, Radiopharmaceuticals, Positron-Emission Tomography, Magnetic Resonance Imaging, Adoptive Transfer, Electroporation, Cell Survival, Protein Binding, Molecular Imaging, Cell Tracking, Antigens, CD19, Receptors, Antigen, T-Cell
Abstract

Genetically-modified T cells expressing chimeric antigen receptors (CAR) exert anti-tumor effect by identifying tumor-associated antigen (TAA), independent of major histocompatibility complex. For maximal efficacy and safety of adoptively transferred cells, imaging their biodistribution is critical. This will determine if cells home to the tumor and assist in moderating cell dose. Here, T cells are modified to express CAR. An efficient, non-toxic process with potential for cGMP compliance is developed for loading high cell number with multi-modal (PET-MRI) contrast agents (Super Paramagnetic Iron Oxide Nanoparticles - Copper-64; SPION-(64)Cu). This can now be potentially used for (64)Cu-based whole-body PET to detect T cell accumulation region with high-sensitivity, followed by SPION-based MRI of these regions for high-resolution anatomically correlated images of T cells. CD19-specific-CAR(+)SPION(pos) T cells effectively target in vitro CD19(+) lymphoma.

Published
2014

16. A physical sciences network characterization of non-tumorigenic and metastatic cells

Author

Agus, David B, Alexander, Jenolyn F, Arap, Wadih, Ashili, Shashanka, Aslan, Joseph E, Austin, Robert H, Backman, Vadim, Bethel, Kelly J, Bonneau, Richard, Chen, Wei-Chiang, Chen-Tanyolac, Chira, Choi, Nathan C, Curley, Steven A, Dallas, Matthew, Damania, Dhwanil, Davies, Paul CW, Decuzzi, Paolo, Dickinson, Laura, Estevez-Salmeron, Luis, Estrella, Veronica, Ferrari, Mauro, Fischbach, Claudia, Foo, Jasmine, Fraley, Stephanie I, Frantz, Christian, Fuhrmann, Alexander, Gascard, Philippe, Gatenby, Robert A, Geng, Yue, Gerecht, Sharon, Gillies, Robert J, Godin, Biana, Grady, William M, Greenfield, Alex, Hemphill, Courtney, Hempstead, Barbara L, Hielscher, Abigail, Hillis, W Daniel, Holland, Eric C, Ibrahim-Hashim, Arig, Jacks, Tyler, Johnson, Roger H, Joo, Ahyoung, Katz, Jonathan E, Kelbauskas, Laimonas, Kesselman, Carl, King, Michael R, Konstantopoulos, Konstantinos, Kraning-Rush, Casey M, Kuhn, Peter, Kung, Kevin, Kwee, Brian, Lakins, Johnathon N, Lambert, Guillaume, Liao, David, Licht, Jonathan D, Liphardt, Jan T, Liu, Liyu, Lloyd, Mark C, Lyubimova, Anna, Mallick, Parag, Marko, John, McCarty, Owen JT, Meldrum, Deirdre R, Michor, Franziska, Mumenthaler, Shannon M, Nandakumar, Vivek, O'Halloran, Thomas V, Oh, Steve, Pasqualini, Renata, Paszek, Matthew J, Philips, Kevin G, Poultney, Christopher S, Rana, Kuldeepsinh, Reinhart-King, Cynthia A, Ros, Robert, Semenza, Gregg L, Senechal, Patti, Shuler, Michael L, Srinivasan, Srimeenakshi, Staunton, Jack R, Stypula, Yolanda, Subramanian, Hariharan, Tlsty, Thea D, Tormoen, Garth W, Tseng, Yiider, van Oudenaarden, Alexander, Verbridge, Scott S, Wan, Jenny C, Weaver, Valerie M, Widom, Jonathan, Will, Christine, Wirtz, Denis, Wojtkowiak, Jonathan, and Wu, Pei-Hsun

Subjects
Biochemistry and Cell Biology, Biological Sciences, Cancer, Breast Cancer, Biotechnology, Aetiology, 2.1 Biological and endogenous factors, Biomarkers, Tumor, Cell Line, Tumor, Cell Movement, Cell Size, Cell Survival, Computer Simulation, Gene Expression Regulation, Neoplastic, Humans, Models, Biological, Neoplasm Metastasis, Neoplasm Proteins, Physical Sciences - Oncology Centers Network
Abstract

To investigate the transition from non-cancerous to metastatic from a physical sciences perspective, the Physical Sciences-Oncology Centers (PS-OC) Network performed molecular and biophysical comparative studies of the non-tumorigenic MCF-10A and metastatic MDA-MB-231 breast epithelial cell lines, commonly used as models of cancer metastasis. Experiments were performed in 20 laboratories from 12 PS-OCs. Each laboratory was supplied with identical aliquots and common reagents and culture protocols. Analyses of these measurements revealed dramatic differences in their mechanics, migration, adhesion, oxygen response, and proteomic profiles. Model-based multi-omics approaches identified key differences between these cells' regulatory networks involved in morphology and survival. These results provide a multifaceted description of cellular parameters of two widely used cell lines and demonstrate the value of the PS-OC Network approach for integration of diverse experimental observations to elucidate the phenotypes associated with cancer metastasis.

Published
2013

17. A physical sciences network characterization of non-tumorigenic and metastatic cells.

Author

Physical Sciences - Oncology Centers Network, Agus, David B, Alexander, Jenolyn F, Arap, Wadih, Ashili, Shashanka, Aslan, Joseph E, Austin, Robert H, Backman, Vadim, Bethel, Kelly J, Bonneau, Richard, Chen, Wei-Chiang, Chen-Tanyolac, Chira, Choi, Nathan C, Curley, Steven A, Dallas, Matthew, Damania, Dhwanil, Davies, Paul CW, Decuzzi, Paolo, Dickinson, Laura, Estevez-Salmeron, Luis, Estrella, Veronica, Ferrari, Mauro, Fischbach, Claudia, Foo, Jasmine, Fraley, Stephanie I, Frantz, Christian, Fuhrmann, Alexander, Gascard, Philippe, Gatenby, Robert A, Geng, Yue, Gerecht, Sharon, Gillies, Robert J, Godin, Biana, Grady, William M, Greenfield, Alex, Hemphill, Courtney, Hempstead, Barbara L, Hielscher, Abigail, Hillis, W Daniel, Holland, Eric C, Ibrahim-Hashim, Arig, Jacks, Tyler, Johnson, Roger H, Joo, Ahyoung, Katz, Jonathan E, Kelbauskas, Laimonas, Kesselman, Carl, King, Michael R, Konstantopoulos, Konstantinos, Kraning-Rush, Casey M, Kuhn, Peter, Kung, Kevin, Kwee, Brian, Lakins, Johnathon N, Lambert, Guillaume, Liao, David, Licht, Jonathan D, Liphardt, Jan T, Liu, Liyu, Lloyd, Mark C, Lyubimova, Anna, Mallick, Parag, Marko, John, McCarty, Owen JT, Meldrum, Deirdre R, Michor, Franziska, Mumenthaler, Shannon M, Nandakumar, Vivek, O'Halloran, Thomas V, Oh, Steve, Pasqualini, Renata, Paszek, Matthew J, Philips, Kevin G, Poultney, Christopher S, Rana, Kuldeepsinh, Reinhart-King, Cynthia A, Ros, Robert, Semenza, Gregg L, Senechal, Patti, Shuler, Michael L, Srinivasan, Srimeenakshi, Staunton, Jack R, Stypula, Yolanda, Subramanian, Hariharan, Tlsty, Thea D, Tormoen, Garth W, Tseng, Yiider, van Oudenaarden, Alexander, Verbridge, Scott S, Wan, Jenny C, Weaver, Valerie M, Widom, Jonathan, Will, Christine, Wirtz, Denis, Wojtkowiak, Jonathan, and Wu, Pei-Hsun

Subjects
Physical Sciences - Oncology Centers Network, Cell Line, Tumor, Humans, Neoplasm Metastasis, Neoplasm Proteins, Cell Movement, Cell Size, Cell Survival, Gene Expression Regulation, Neoplastic, Models, Biological, Computer Simulation, Biomarkers, Tumor, Cancer, Breast Cancer, Biotechnology, 2.1 Biological and endogenous factors
Abstract

To investigate the transition from non-cancerous to metastatic from a physical sciences perspective, the Physical Sciences-Oncology Centers (PS-OC) Network performed molecular and biophysical comparative studies of the non-tumorigenic MCF-10A and metastatic MDA-MB-231 breast epithelial cell lines, commonly used as models of cancer metastasis. Experiments were performed in 20 laboratories from 12 PS-OCs. Each laboratory was supplied with identical aliquots and common reagents and culture protocols. Analyses of these measurements revealed dramatic differences in their mechanics, migration, adhesion, oxygen response, and proteomic profiles. Model-based multi-omics approaches identified key differences between these cells' regulatory networks involved in morphology and survival. These results provide a multifaceted description of cellular parameters of two widely used cell lines and demonstrate the value of the PS-OC Network approach for integration of diverse experimental observations to elucidate the phenotypes associated with cancer metastasis.

Published
2013

24. Sex Related Differences and Factors Associated With Peri-Procedural and One Year Mortality in Chronic Limb Threatening Ischaemia Patients

Author

Martelli, Eugenio, Zamboni, Matilde, Sotgiu, Giovanni, Saderi, Laura, Federici, Massimo, Sangiorgi, Giuseppe, Puci, Mariangela Valentina, Martelli, Allegra Rosa, Messina, Teresa, Frigatti, Paolo, Borrelli, Maria Pia, Ruotolo, Carlo, Ficarelli, Ilaria, Rubino, Paolo, Pezzo, Francesco, Carbonari, Luciano, Angelini, Andrea, Galeazzi, Edoardo, Calia di Pinto, Luca, Fiore, Franco Michelino, Palmieri, Armando, Ventoruzzo, Giorgio, Mazzitelli, Giulia, Ragni, Franco, Bozzani, Antonio, Forliti, Enzo, Castagno, Claudio, Volpe, Pietro, Massaro, Mafalda, Moniaci, Diego, Pagliasso, Elisa, Peretti, Tania, Ferrari, Mauro, Troisi, Nicola, Modugno, Piero, Maiorano, Maurizio, Bracale, Umberto Marcello, Panagrosso, Marco, Monaco, Mario, Giordano, Giovanni, Natalicchio, Giuseppe, Biello, Antonella, Celoria, Giovanni Maria, Amico, Alessio, Di Bartolo, Mauro, Martelli, Massimiliano, Munaò, Roberta, Razzano, Davide, Colacchio, Giovanni, Bussetti, Francesco, Lanza, Gaetano, Cardini, Antonio, Di Benedetto, Bartolomeo, De Laurentis, Mario, Taurino, Maurizio, Sirignano, Pasqualino, Cappiello, Pierluigi, Esposito, Andrea, Trimarchi, Santi, Romagnoli, Silvia, Padricelli, Andrea, Giudice, Giorgio, Crinisio, Adolfo, Di Nardo, Giovanni, Battaglia, Giuseppe, Tringale, Rosario, De Vivo, Salvatore, Compagna, Rita, Tolva, Valerio Stefano, D'Alessio, Ilenia, Curci, Ruggiero, Giovannetti, Simona, D'Arrigo, Giuseppe, Basile, Giusi, Frigerio, Dalmazio, Veraldi, Gianfranco, Mezzetto, Luca, Ippoliti, Arnaldo, Oddi, Fabio Massimo, and Settembrini, Alberto Maria

Published
2024
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25. Sex-Related Differences and Factors Associated with Peri-Procedural and 1 Year Mortality in Chronic Limb-Threatening Ischemia Patients from the CLIMATE Italian Registry

Author

Martelli, Eugenio, primary, Zamboni, Matilde, additional, Sotgiu, Giovanni, additional, Saderi, Laura, additional, Federici, Massimo, additional, Sangiorgi, Giuseppe M., additional, Puci, Mariangela V., additional, Martelli, Allegra R., additional, Messina, Teresa, additional, Frigatti, Paolo, additional, Borrelli, Maria Pia, additional, Ruotolo, Carlo, additional, Ficarelli, Ilaria, additional, Rubino, Paolo, additional, Pezzo, Francesco, additional, Carbonari, Luciano, additional, Angelini, Andrea, additional, Galeazzi, Edoardo, additional, Di Pinto, Luca Calia, additional, Fiore, Franco M., additional, Palmieri, Armando, additional, Ventoruzzo, Giorgio, additional, Mazzitelli, Giulia, additional, Ragni, Franco, additional, Bozzani, Antonio, additional, Forliti, Enzo, additional, Castagno, Claudio, additional, Volpe, Pietro, additional, Massara, Mafalda, additional, Moniaci, Diego, additional, Pagliasso, Elisa, additional, Peretti, Tania, additional, Ferrari, Mauro, additional, Troisi, Nicola, additional, Modugno, Piero, additional, Maiorano, Maurizio, additional, Bracale, Umberto M., additional, Panagrosso, Marco, additional, Monaco, Mario, additional, Giordano, Giovanni, additional, Natalicchio, Giuseppe, additional, Biello, Antonella, additional, Celoria, Giovanni M., additional, Amico, Alessio, additional, Di Bartolo, Mauro, additional, Martelli, Massimiliano, additional, Munaó, Roberta, additional, Razzano, Davide, additional, Colacchio, Giovanni, additional, Bussetti, Francesco, additional, Lanza, Gaetano, additional, Cardini, Antonio, additional, Di Benedetto, Bartolomeo, additional, De Laurentis, Mario, additional, Taurino, Maurizio, additional, Sirignano, Pasqualino, additional, Cappiello, Pierluigi, additional, Esposito, Andrea, additional, Trimarchi, Santi, additional, Romagnoli, Silvia, additional, Padricelli, Andrea, additional, Giudice, Giorgio, additional, Crinisio, Adolfo, additional, Di Nardo, Giovanni, additional, Battaglia, Giuseppe, additional, Tringale, Rosario, additional, De Vivo, Salvatore, additional, Compagna, Rita, additional, Tolva, Valerio S., additional, D’Alessio, Ilenia, additional, Curci, Ruggiero, additional, Giovannetti, Simona, additional, D’Arrigo, Giuseppe, additional, Basile, Giusi, additional, Frigerio, Dalmazio, additional, Veraldi, Gian Franco, additional, Mezzetto, Luca, additional, Ippoliti, Arnaldo, additional, Oddi, Fabio M., additional, and Settembrini, Alberto M., additional

Published
2023
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26. Antithrombotic therapy following revascularization for chronic limb-threatening ischaemia:a European survey from the ESC Working Group on Aorta and Peripheral Vascular Diseases

Author

De Carlo, Marco, Schlager, Oliver, Mazzolai, Lucia, Brodmann, Marianne, Espinola-Klein, Christine, Staub, Daniel, Aboyans, Victor, Sillesen, Henrik, Debus, Sebastian, Venermo, Maarit, Belch, Jill, Ferrari, Mauro, De Caterina, Raffaele, De Carlo, Marco, Schlager, Oliver, Mazzolai, Lucia, Brodmann, Marianne, Espinola-Klein, Christine, Staub, Daniel, Aboyans, Victor, Sillesen, Henrik, Debus, Sebastian, Venermo, Maarit, Belch, Jill, Ferrari, Mauro, and De Caterina, Raffaele

Abstract

AIMS: Chronic limb-threatening ischaemia (CLTI) entails dismal outcomes and is an absolute indication to lower extremity revascularization (LER) whenever possible. Antithrombotic therapy is here crucial, but available evidence on best strategies (choice of drugs, combinations, duration) is scarce. We conducted a European internet-based survey on physicians' use of antithrombotic therapy after revascularization for CLTI, under the aegis of the ESC Working Group on Aorta and Peripheral Vascular Disease in collaboration with other European scientific societies involved in CLTI management and agreeing to send the survey to their affiliates. METHODS AND RESULTS: 225 respondents completed the questionnaire. Antithrombotic therapy following surgical/endovascular LER varies widely across countries and specialties, with dedicated protocols reported only by a minority (36%) of respondents. Dual antiplatelet therapy with aspirin and clopidogrel is the preferred choice for surgical (37%) and endovascular (79%) LER. Dual pathway inhibition (DPI) with aspirin and low-dose rivaroxaban is prescribed by 16% of respondents and is tightly related to the availability of reimbursement (OR 6.88; 95% CI 2.60-18.25) and to the choice of clinicians rather than of physicians performing revascularization (OR 2.69; 95% CI 1.10-6.58). A ≥ 6 months-duration of an intense (two-drug) postprocedural antithrombotic regimen is more common among surgeons than among medical specialists (OR 2.08; 95% CI 1.10-3.94). Bleeding risk assessment is not standardised and likely underestimated. CONCLUSION: Current antithrombotic therapy of CLTI patients undergoing LER remains largely discretional, and prescription of DPI is related to reimbursement policies. An individualised assessment of thrombotic and bleeding risks is largely missing.

Published
2023

28. Detecting exposure to environmental organic toxins in individual cells: towards development of a micro-fabricated device

Author

Holman, Hoi-Ying N., Zhang, Miqin, Goth-Goldstein, Regine, Martin, Michael C., Russell, Marion, McKinney, Wayne R., Ferrari, Mauro, and Hunter-Cevera, Jennie C.

Subjects
Environmental sciences, Polycyclic aromatic hydrocarbons (PAHs) Organochlorines (OCs) dioxin infrared spectroscopy CYP1A1 RT-PCR advanced light source als
Abstract

A new method is being developed to quickly screen for the human exposure potential to polycyclic aromatic hydrocarbons (PAHs) and organochlorines (OCs). The development involves two key elements: identifying suitable signals that represent intracellular changes that are specific to PAH and OC exposure, and constructing a device to guide the biological cell growth so that signals from individual cells are consistent and reproducible. We are completing the identification of suitable signals by using synchrotron radiation-based (SR) Fourier-transform infrared (FTIR) spectromicroscopy in the mid-infrared region (4000-400 cm-1). Distinct changes have been observed in the IR spectra after treatment of human cells in culture medium with PAHs and OCs. The potential use of this method for detecting exposure to PAHs and OCs has been tested and compared to a reverse transcription polymerase chain reaction (RT-PCR) assay that quantifies increased expression of the CYP1A1 gene in response to exposure to PAHs or OCs.

Published
1999

36. [18F]-Fludeoxyglucose Positron Emission Tomography/Computed Tomography with Radiomics Analysis in Patients Undergoing Aortic In-Situ Reconstruction with Cryopreserved Allografts

Author

Berchiolli, Raffaella, primary, Torri, Lorenzo, additional, Bertagna, Giulia, additional, Canovaro, Francesco, additional, Zanca, Roberta, additional, Bartoli, Francesco, additional, Mocellin, Davide Maria, additional, Ferrari, Mauro, additional, Erba, Paola Anna, additional, and Troisi, Nicola, additional

Published
2022
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