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87 results on '"Di Gregorio M."'

1. Clinical characteristics of vulnerable populations hospitalized and diagnosed with COVID-19 in Buenos Aires, Argentina

Author: Yacobitti, A., Otero, L., Doldan Arrubarrena, V., Arano, J., Lage, S., Silberman, M., Zubieta, M., Erbetta, I., Danei, P., Baeck, G., Vallejos, V., Cavalli, F., Calderón, N., Di Gregorio, M., Hernandez, V., Bruno, D., Rodera, B., Macherett, I., Parisi, M., Gallastegui, M., Paz, A., Bernardi, R., Azcárate, S., Hraste, A., Caridi, I., Boechi, L., Salgado, P., and Kochen, S.
Published: 2021
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2. Publisher Correction: Clinical characteristics of vulnerable populations hospitalized and diagnosed with COVID-19 in Buenos Aires, Argentina

Author: Yacobitti, A., Otero, L., Arrubarrena, V. Doldan, Arano, J., Lage, S., Silberman, M., Zubieta, M., Erbetta, I., Danei, P., Baeck, G., Vallejos, V., Cavalli, F., Calderón, N., Di Gregorio, M., Hernandez, V., Bruno, D., Rodera, B., Macherett, I., Parisi, M., Gallastegui, M., Paz, A., Bernardi, R., Azcárate, S., Hraste, A., Caridi, I., Boechi, L., Salgado, P., and Kochen, S.
Published: 2021
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3. Biomonitoring of a Worker Population Exposed to Platinum Dust in a Catalyst Production Plant

Author: Petrucci, F., Violante, N., Senofonte, O., Cristaudo, A., Di Gregorio, M., Forte, G., and Alimonti, A.
Published: 2005
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4. Late vitreomacular traction in toxoplasma retinochoroiditis resolved by vitrectomy

Author: Scarpa G, Fabris S, Di Gregorio M, and Urban F
Subjects: Ophthalmology, RE1-994
Abstract: Giuseppe Scarpa, Stefano Fabris, Marco Di Gregorio, Francesca Urban Ophthalmic Department Regional Hospital, Ca' Foncello Piazza Ospedale 1, Treviso, Italy Abstract: This paper reports a case of late vitreomacular traction in a young patient secondary to toxoplasma retinochoroiditis resolved by vitrectomy. A 17-year-old female with chronic inflammatory bowel disease developed severe vitreomacular traction 8 months after resolution of ocular toxoplasmosis with medical therapy. Best-corrected visual acuity, full ophthalmic slit-lamp examination, colour fundus photography, spectral domain optical coherence tomography, and fluorescein angiography were performed. The patient underwent vitrectomy with removal of the clinically evident posterior hyaloid. Vitrectomy was rapidly successful in resolving the vitreomacular traction, with full recovery in best-corrected visual acuity of 20/20. Vitreoretinal traction in patients with previous toxoplasma retinochoroiditis may appear several months after resolution of the inflammatory condition. We suggest observing carefully for possible development of late vitreoretinal traction during follow-up of such patients. Keywords: ocular toxoplasmosis, toxoplasma retinochoroiditis, vitreomacular traction, vitrectomy, inflammatory bowel disease
Published: 2013

5. REDD+ policy implementation and institutional interplay: Evidence from three pilot projects in Cameroon

Author: Gakou-Kakeu J., Di Gregorio M., Paavola J., and Sonwa D.J.
Published: 2020
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6. On the side of the apes T H Huxley and the method and results of science

Author: Di Gregorio, M. A.
Subjects: 509
Published: 1979

7. Multimedia information broadcasting using digital TV channels

Author: Atzori, L., de Natale, F.G.B., Di Gregorio, M., and Giusto, D.D.
Subjects: Digital television -- Standards, Multimedia technology -- Management, Television broadcasting -- Standards, Image processing -- Standards, Digital electronics, Business, Electronics, Mass communications
Published: 1997

8. What drives policy change for REDD A qualitative comparative analysis of the interplay between institutional and policy arena factors

Author: Korhonen-Kurki, K. Brockhaus, M. Sehring, J. Di Gregorio, M. Assembe-Mvondo, S. Babon, A. Bekele, M. Benn, V. Gebara, M. F. Kambire, H. W. Kengoum, F. Maharani, C. Menton, M. Moeliono, M. Ochieng, R. Paudel, N. S. Pham, T. T. Dkamela, G. P. Sitoe, A. and Korhonen-Kurki, K. Brockhaus, M. Sehring, J. Di Gregorio, M. Assembe-Mvondo, S. Babon, A. Bekele, M. Benn, V. Gebara, M. F. Kambire, H. W. Kengoum, F. Maharani, C. Menton, M. Moeliono, M. Ochieng, R. Paudel, N. S. Pham, T. T. Dkamela, G. P. Sitoe, A.
Abstract: Reducing Emissions from Deforestation and forest Degradation (REDD+) has emerged as a promising climate change mitigation mechanism in developing countries. In order to identify the enabling conditions for achieving progress in the implementation of an effective, efficient and equitable REDD+, this paper examines national policy settings in a comparative analysis across 13 countries with a focus on both institutional context and the actual setting of the policy arena. The evaluation of REDD+ revealed that countries across Africa, Asia and Latin America are showing some progress, but some face backlashes in realizing the necessary transformational change to tackle deforestation and forest degradation. A Qualitative Comparative Analysis (QCA) undertaken as part of the research project showed two enabling institutional configurations facilitating progress: (1) the presence of already initiated policy change; and (2) scarcity of forest resources combined with an absence of any effective forestry framework and policies. When these were analysed alongside policy arena conditions, the paper finds that the presence of powerful transformational coalitions combined with strong ownership and leadership, and performance-based funding, can both work as a strong incentive for achieving REDD+ goals.
Published: 2019
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9. The TEEBAgriFood theory of change: from information to action

Author: May, PH, Platais, G, Di Gregorio, M, Gowdy, J, Pinto, LFG, Laurans, Y, Cervone, COFO, Rankovic, AA, Santamaria, M, and UN Environment
Abstract: KEY MESSAGES • Information alone often fails to motivate change. Manipulation of data has led consumers to doubt scientific results, serving special interests at the expense of public benefit. Information overload implies the need for synthesis to enable better access and impact. • Rationalizations against the need for change include: fatalism, arguing that business is already changing of its own accord, that cheap food is more important than good food, and that the marketplace will adjust for externalities. • These views do not address the long-term systemic consequences of the global corporate model of food systems in a society that derives calories from corn syrup and protein from hamburger resulting in obesity and disease. • Free market, neoliberal policies are incapable of resolving externalities that affect public goods such as ecosystem services. Faith in the infallibility of the market is a shortcoming of mainstream economics. • Path dependency is a key barrier to change in food systems, causing inertia, but may also lock-in positive systemic change. A science of intentional systemic change is arising, grounded in better understanding of human economic behavior as the basis for collective action. • We espouse not one theory but rather a range of actor-relevant theories of change. • Consumer advocacy can bring businesses to assume greater responsibility for the effects of their actions. This theory of change has found expression in the threat of boycotts and reputational risk. • Certification has led to improvement in production practice within market niches but its true success begins when it pressures change in policy and practice throughout supply chains. • Governance of intentional transformation in food systems requires knowledge of political pressure points, and systematic efforts to shape narratives of principal actors, to redirect financial resources and to promote institutional and societal learning and adaptation. • We address the potential of multilateral organizations and agreements, national governments, the financial industry, agribusiness, producers and consumer groups to respond to the need for change. The roles of different actors are interlocking: there is no single point of entry for a theory of change. • The roles of principal actors are drawn along a continuum of change, suggesting specific roles and types of actions to be addressed in evaluation and intervention. Given societal concern, agents for change may persevere within government, agribusiness or civil society organizations; their ability to bring change is dynamic and opportunistic, and driven by strategic alliances. As levers of agrifood system transformation, it is crucial to engage influential governmental actors as change agents. • Actors’ respective ability to adopt the results of TEEBAgriFood studies as a tool to direct change will depend on how well those results are communicated and adopted as narratives by influential actors and as entry points for education and consumer consciousness.
Published: 2018

10. La valutazione parlamentare delle politiche pubbliche nella determinazione della forma di governo britannica: un’analisi di impatto

Author: Serafin, E, Toniato, F, Caretti, P, Morisi, M, Cordova, C, De Tura, M, Lampariello, L, Palermo, M, Piccione, S, Scarlato, I, Bucci, E, Cavaletto, T, D’Ippolito, G, Facciano, V, Milani, G, Olia, F, Carcangiu, D, Mandato, M, Mitrotti, A, Monti, M, Pisaneschi, A, Rossin, M, Canini, M, Di Gregorio, M, Liotti, M, Passeri, M, Patera, M, Pazzaglia, G, Serafin, E, Toniato, F, Caretti, P, Morisi, M, Cordova, C, De Tura, M, Lampariello, L, Palermo, M, Piccione, S, Scarlato, I, Bucci, E, Cavaletto, T, D’Ippolito, G, Facciano, V, Milani, G, Olia, F, Carcangiu, D, Mandato, M, Mitrotti, A, Monti, M, Pisaneschi, A, Rossin, M, Canini, M, Di Gregorio, M, Liotti, M, Passeri, M, Patera, M, and Pazzaglia, G
Published: 2018

11. Treatment of multiple sclerosis relapses with high-dose methylprednisolone reduces the evolution of contrast-enhancing lesions into persistent black holes

Author: Di Gregorio, M., Gaetani, L., Eusebi, P., Floridi, P., Picchioni, A., Rosi, G., Mancini, A., Floridi, C., Baschieri, F., Gentili, L., Sarchielli, P., Calabresi, Paolo, Di Filippo, M., Calabresi P. (ORCID:0000-0003-0326-5509), Di Gregorio, M., Gaetani, L., Eusebi, P., Floridi, P., Picchioni, A., Rosi, G., Mancini, A., Floridi, C., Baschieri, F., Gentili, L., Sarchielli, P., Calabresi, Paolo, Di Filippo, M., and Calabresi P. (ORCID:0000-0003-0326-5509)
Abstract: Introduction: The MRI evidence of persistent black holes (pBHs) on T1-weighted images reflects brain tissue loss in multiple sclerosis (MS). The evolution of contrast-enhancing lesions (CELs) into pBHs probably depends on the degree and persistence of focal brain inflammation. The aim of our retrospective study was to evaluate the effect of a single cycle of intravenous methylprednisolone (IVMP), as for MS relapse treatment, on the risk of CELs’ evolution into pBHs. Patients and methods: We selected 57 patients with CELs on the baseline MRI scan. We evaluated the evolution of CELs into pBHs on a follow-up MRI scan performed after ≥ 6 months in patients exposed and not exposed to IVMP for the treatment of relapse after the baseline MRI. Results: In our cohort, 182 CELs were identified in the baseline MRI and 57 of them (31.3%) evolved into pBHs. In the multivariate analysis, the exposure of CELs to IVMP resulted to be a significant independent protective factor against pBHs’ formation (OR 0.28, 95% CI 0.11–0.766, p = 0.005), while ring enhancement pattern and the fact of being symptomatic were significant risk factors for CELs’ conversion into pBHs (OR 6.42, 95% CI 2.55–17.27, p OpenSPiltSPi 0.001 and OR 13.19, 95% CI 1.56–288.87, p = 0.037). Conclusions: The exposure of CELs to a cycle of IVMP as for relapse treatment is associated with a lower risk of CELs’ evolution into pBHs. Future studies are required to confirm the potential independent protective effect of IVMP on CELs’ evolution into pBHs.
Published: 2018

12. Drug-induced Creutzfeldt-Jakob disease-like syndrome: Early CSF analysis as useful tool for differential diagnosis

Author: Paoletti, F. P., Di Gregorio, M., Calabresi, P., Parnetti, L., Calabresi P. (ORCID:0000-0003-0326-5509), Paoletti, F. P., Di Gregorio, M., Calabresi, P., Parnetti, L., and Calabresi P. (ORCID:0000-0003-0326-5509)
Abstract: We report the case of a 78-year-old man who showed a subacute onset of severe cognitive impairment, ataxia, tremor, stimulus sensitive myoclonus and hypophonia. Since a few weeks, he received a treatment with a combination of tricyclic antidepressants for mood disorder. The clinical picture mimicked Creutzfeldt-Jakob disease (CJD), but we could rule out this diagnosis by means of cerebrospinal fluid (CSF) analysis, which showed normal level of tau protein and Aß1-42, being also negative for CSF 14-3-3 protein. A complete clinical recovery was observed after the discontinuation of antidepressants. So far, some cases of drug-induced CJD-like syndrome have been described. In our experience, early CSF analysis shows high diagnostic usefulness in order to exclude CJD.
Published: 2018

13. No evidence of disease activity (NEDA-3) and disability improvement after alemtuzumab treatment for multiple sclerosis: a 36-month real-world study

Author: Prosperini, L., Annovazzi, P., Boffa, L., Buscarinu, M. C., Gallo, A., Matta, M., Moiola, L., Musu, L., Perini, P., Avolio, C., Barcella, V., Bianco, Assunta, Farina, D., Ferraro, E., Pontecorvo, S., Granella, F., Grimaldi, L. M. E., Laroni, A., Lus, G., Patti, F., Pucci, E., Pasca, M., Sarchielli, P., Ghezzi, A., Zaffaroni, M., Baroncini, D., Buttari, F., Centonze, D., Fornasiero, A., Salvetti, M., Docimo, R., Signoriello, E., Tedeschi, G., Bertolotto, A., Capobianco, M., Comi, G., Cocco, E., Gallo, P., Puthenparampil, M., Grasso, R., Di Francescantonio, V., Rottoli, M. R., Mirabella, Massimiliano, Lugaresi, A., De Luca, G., Di Ioia, M., Di Tommaso, V., Mancinelli, L., Di Battista, G., Francia, A., Ruggieri, S., Pozzilli, C., Curti, E., Tsantes, E., Palmeri, B., Lapicci, C., Mancardi, G. L., Uccelli, A., Chisari, C., D'Amico, E., Cartechini, E., Repice, A. M., Magnani, E., Massaccesi, L., Calabresi, Paolo, Di Filippo, Mario, Di Gregorio, M., Bianco A., Mirabella M. (ORCID:0000-0002-7783-114X), Calabresi P. (ORCID:0000-0003-0326-5509), Di Filippo M., Prosperini, L., Annovazzi, P., Boffa, L., Buscarinu, M. C., Gallo, A., Matta, M., Moiola, L., Musu, L., Perini, P., Avolio, C., Barcella, V., Bianco, Assunta, Farina, D., Ferraro, E., Pontecorvo, S., Granella, F., Grimaldi, L. M. E., Laroni, A., Lus, G., Patti, F., Pucci, E., Pasca, M., Sarchielli, P., Ghezzi, A., Zaffaroni, M., Baroncini, D., Buttari, F., Centonze, D., Fornasiero, A., Salvetti, M., Docimo, R., Signoriello, E., Tedeschi, G., Bertolotto, A., Capobianco, M., Comi, G., Cocco, E., Gallo, P., Puthenparampil, M., Grasso, R., Di Francescantonio, V., Rottoli, M. R., Mirabella, Massimiliano, Lugaresi, A., De Luca, G., Di Ioia, M., Di Tommaso, V., Mancinelli, L., Di Battista, G., Francia, A., Ruggieri, S., Pozzilli, C., Curti, E., Tsantes, E., Palmeri, B., Lapicci, C., Mancardi, G. L., Uccelli, A., Chisari, C., D'Amico, E., Cartechini, E., Repice, A. M., Magnani, E., Massaccesi, L., Calabresi, Paolo, Di Filippo, Mario, Di Gregorio, M., Bianco A., Mirabella M. (ORCID:0000-0002-7783-114X), Calabresi P. (ORCID:0000-0003-0326-5509), and Di Filippo M.
Abstract: In this retrospective, multicenter, real-world study we collected clinical and magnetic resonance imaging (MRI) data of all patients (n = 40) with relapsing-remitting multiple sclerosis (RRMS) treated with alemtuzumab according to a “free-of-charge” protocol available before the drug marketing approval in Italy. Almost all (39/40) started alemtuzumab after discontinuing multiple disease-modifying treatments (DMTs) because of either lack of response or safety concerns. We considered the proportion of alemtuzumab-treated patients who had no evidence of disease activity (NEDA-3) and disability improvement over a 36-month follow-up period. NEDA-3 was defined as absence of relapses, disability worsening, and MRI activity. Disability improvement was defined as a sustained reduction of ≥ 1-point in Expanded Disability Status Scale (EDSS) score. At follow-up, 18 (45%) patients achieved NEDA-3, 30 (75%) were relapse-free, 33 (82.5%) were EDSS worsening-free, and 25 (62.5%) were MRI activity-free. Eleven (27.5%) patients had a sustained disability improvement. We found no predictor for the NEDA-3 status, while the interaction of higher EDSS score by higher number of pre-alemtuzumab relapses was associated with a greater chance of disability improvement (odds ratio 1.10, p = 0.049). Our study provides real-world evidence that alemtuzumab can promote clinical and MRI disease remission, as well as disability improvement, in a significant proportion of patients with RRMS despite prior multiple DMT failures. The drug safety profile was consistent with data available from clinical trials.
Published: 2018

14. Framing REDD+ in the Brazilian national media: how discourses evolved amid global negotiation uncertainties

Author: Gebara, MF, May, PH, Carmenta, R, Calixto, B, Brockhaus, M, and Di Gregorio, M
Abstract: Reducing emissions from deforestation and degradation (REDD+) in tropical countries is an important and contested element of the post-Kyoto climate regime. For policy options which generate controversy between diverse actor groups, such as REDD+, mass media plays an important role in defining and supporting policy possibilities. Analysis of the way in which national media frames issues of climate change and deforestation can offer insights into the nature of the contested domains of the REDD+ policy process. Here, we examine the Brazilian national media discourses surrounding REDD+ because it contributes to setting the tone of policy debates at the federal level. Specifically, we ask the following: (i) How was REDD+ portrayed in the Brazilian national print media and whose opinions and perceptions were represented? and (ii) How have media frames on REDD+ in the national print media changed over time? Our results contribute with new knowledge for understanding the observed progress of REDD+ in Brazil. We identify two main themes that dominate the focus in the national media coverage of REDD+, specifically “politics and policymaking” (representing half the coverage) and “economics and market” (with over a third). Results show that discussions around carbon markets were amongst the most contested and that optimism in relation to REDD+ effectiveness declined over time. The analysis suggests that positions adopted on the national REDD+ strategy were shaped by state and federal collision of interests. We demonstrate an evolution of national concerns from an initial focus on efficiency (e.g. finance and carbon markets) to a recentred focus on equity issues (e.g. implementation of safeguards). We conclude with some thoughts on the implications of these features for REDD+ interventions and implementation in Brazil.
Published: 2017

15. Abstracts of the Eighth EDCTP Forum, 6-9 November 2016.

Author: Makanga, M, Beattie, P, Breugelmans, G, Nyirenda, T, Bockarie, M, Tanner, M, Volmink, J, Hankins, C, Walzl, G, Chegou, N, Malherbe, S, Hatherill, M, Scriba, TJ, Zak, DE, Barry, CE, Kaufmann, SHE, Noor, A, Strub-Wourgaft, N, Phillips, P, Munguambe, K, Ravinetto, R, Tinto, H, Diro, E, Mahendrahata, Y, Okebe, J, Rijal, S, Garcia, C, Sundar, S, Ndayisaba, G, Sopheak, T, Ngoduc, T, Van Loen, H, Jacobs, J, D'Alessandro, U, Boelaert, M, Buvé, A, Kamalo, P, Manda-Taylor, L, Rennie, S, Mokgatla, B, Bahati, Ijsselmuiden, C, Afolabi, M, Mcgrath, N, Kampmann, B, Imoukhuede, E, Alexander, N, Larson, H, Chandramohan, D, Bojang, K, Kasaro, MP, Muluka, B, Kaunda, K, Morse, J, Westfall, A, Kapata, N, Kruuner, A, Henostroza, G, Reid, S, Alabi, A, Foguim, F, Sankarganesh, J, Bruske, E, Mfoumbi, A, Mevyann, C, Adegnika, A, Lell, B, Kranzer, K, Kremsner, P, Grobusch, M, Sabiiti, W, Ntinginya, N, Kuchaka, D, Azam, K, Kampira, E, Mtafya, B, Bowness, R, Bhatt, N, Davies, G, Kibiki, G, Gillespie, S, Lejon, V, Ilboudo, H, Mumba, D, Camara, M, Kaba, D, Lumbala, C, Fèvre, E, Jamonneau, V, Bucheton, B, Büscher, P, Chisenga, C, Sinkala, E, Chilengi, R, Chitundu, H, Zyambo, Z, Wandeler, G, Vinikoor, M, Emilie, D, Camara, O, Mathurin, K, Guiguigbaza-Kossigan, D, Philippe, B, Regassa, F, Hassane, S, Bienvenu, SM, Fabrice, C, Ouédraogo, E, Kouakou, L, Owusu, M, Mensah, E, Enimil, A, Mutocheluh, M, Ndongo, FA, Tejiokem, MC, Texier, G, Penda, C, Ndiang, S, Ndongo, J-A, Guemkam, G, Sofeu, CL, Afumbom, K, Faye, A, Msellati, P, Warszawski, J, Vos, A, Devillé, W, Barth, R, Klipstein-Grobusch, K, Tempelman, H, Venter, F, Coutinho, R, Grobbee, D, Ssemwanga, D, Lyagoba, F, Magambo, B, Kapaata, A, Kirangwa, J, Nannyonjo, M, Nassolo, F, Nsubuga, R, Yebra, G, Brown, A, Kaleebu, P, Nylén, H, Habtewold, A, Makonnen, E, Yimer, G, Burhenne, J, Diczfalusy, U, Aklillu, E, Steele, D, Walker, R, Simuyandi, M, Beres, L, Bosomprah, S, Ansumana, R, Taitt, C, Lamin, JM, Jacobsen, KH, Mulvaney, SP, Leski, T, Bangura, U, Stenger, D, De Vries, S, Zinsou, FJ, Honkpehedji, J, Dejon, JC, Loembe, MM, Bache, B, Pakker, N, Van Leeuwen, R, Hounkpatin, AB, Yazdanbakhsh, M, Bethony, J, Hotez, P, Diemert, D, Bache, BE, Fernandes, JF, Obiang, RM, Kabwende, AL, Grobusch, MP, Krishna, S, Kremsner, PG, Todagbe, AS, Nambozi, M, Kabuya, J-B, Hachizovu, S, Mwakazanga, D, Kasongo, W, Buyze, J, Mulenga, M, Geertruyden, J-P, Gitaka, J, Chan, C, Kongere, J, Kagaya, W, Kaneko, A, Kabore, N, Barry, N, Kabre, Z, Werme, K, Fofana, A, Compaore, D, Nikiema, F, Some, F, Djimde, A, Zongo, I, Ouedraogo, B, Kone, A, Sagara, I, Björkman, A, Gil, JP, Nchinda, G, Bopda, A, Nji, N, Ambada, G, Ngu, L, Tchadji, J, Sake, C, Magagoum, S, Njambe, GD, Lisom, A, Park, CG, Tait, D, Sibusiso, H, Manda, O, Croucher, K, Van Der Westhuizen, A, Mshanga, I, Levin, J, Nanvubya, A, Kibengo, F, Jaoko, W, Pala, P, Perreau, M, Namuniina, A, Kitandwe, P, Tapia, G, Serwanga, J, Yates, N, Fast, P, Mayer, B, Montefiori, D, Tomaras, G, Robb, M, Lee, C, Wagner, R, Sanders, E, Kilembe, W, Kiwanuka, N, Gilmour, J, Kuipers, H, Vooij, D, Chinyenze, K, Priddy, F, Ding, S, Hanke, T, Pantaleo, G, Ngasala, B, Jovel, I, Malmberg, M, Mmbando, B, Premji, Z, Mårtensson, A, Mwaiswelo, R, Agbor, L, Apinjoh, T, Mwanza, S, Chileshe, J, Joshi, S, Malunga, P, Manyando, C, Laufer, M, Dara, A, Niangaly, A, Sinha, I, Brodin, D, Fofana, B, Dama, S, Dembele, D, Sidibe, B, Diallo, N, Thera, M, Wright, K, Gil, J, Doumbo, O, Baraka, V, Nabasumba, C, Francis, F, Lutumba, P, Mavoko, H, Alifrangis, M, Van Geertruyden, J-P, Sissoko, S, Sangaré, C, Toure, S, Sanogo, K, Diakite, H, Doumbia, D, Haidara, K, Julé, A, Ashurst, H, Merson, L, Olliaro, P, Marsh, V, Lang, T, Guérin, P, Awuondo, K, Njenga, D, Nyakarungu, E, Titus, P, Sutamihardja, A, Lowe, B, Ogutu, B, Billingsley, P, Soulama, I, Kaboré, M, Coulibaly, A, Ouattara, M, Sanon, S, Diarra, A, Bougouma, E, Ouedraogo, A, Sombie, B, Kargougou, D, Ouattara, D, Issa, N, Tiono, A, Sirima, S, Chaponda, M, Dabira, E, Dao, F, Dara, N, Coulibaly, M, Tolo, A, Maiga, H, Ouologuem, N, Niangaly, H, Botchway, F, Wilson, N, Dickinson-Copeland, CM, Adjei, AA, Wilson, M, Stiles, JK, Hamid, MA, Awad-Elgeid, M, Nasr, A, Netongo, P, Kamdem, S, Velavan, T, Lasry, E, Diarra, M, Bamadio, A, Traore, A, Coumare, S, Soma, B, Dicko, Y, Sangare, B, Tembely, A, Traore, D, Haidara, A, Dicko, A, Diawara, E, Beavogui, A, Camara, D, Sylla, M, Yattara, M, Sow, A, Camara, GC, Diallo, S, Mombo-Ngoma, G, Remppis, J, Sievers, M, Manego, RZ, Endamne, L, Hutchinson, D, Held, J, Supan, C, Salazar, CLO, Bonkian, LN, Nahum, A, Sié, A, Abdulla, S, Cantalloube, C, Djeriou, E, Bouyou-Akotet, M, Mordmüller, B, Siribie, M, Sirima, SB, Ouattara, SM, Coulibaly, S, Kabore, JM, Amidou, D, Tekete, M, Traore, O, Haefeli, W, Borrmann, S, Kaboré, N, Kabré, Z, Nikèma, F, Compaoré, D, Somé, F, Djimdé, A, Ouédraogo, J, Chalwe, V, Miller, J, Diakité, H, Greco, B, Spangenberg, T, Kourany-Lefoll, E, Oeuvray, C, Mulry, J, 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Endamne, L, Hutchinson, D, Held, J, Supan, C, Salazar, CLO, Bonkian, LN, Nahum, A, Sié, A, Abdulla, S, Cantalloube, C, Djeriou, E, Bouyou-Akotet, M, Mordmüller, B, Siribie, M, Sirima, SB, Ouattara, SM, Coulibaly, S, Kabore, JM, Amidou, D, Tekete, M, Traore, O, Haefeli, W, Borrmann, S, Kaboré, N, Kabré, Z, Nikèma, F, Compaoré, D, Somé, F, Djimdé, A, Ouédraogo, J, Chalwe, V, Miller, J, Diakité, H, Greco, B, Spangenberg, T, Kourany-Lefoll, E, Oeuvray, C, Mulry, J, Tyagarajan, K, Magsaam, B, Barnes, K, Hodel, EM, Humphreys, G, Pace, C, Banda, CG, Denti, P, Allen, E, Lalloo, D, Mwapasa, V, Terlouw, A, Mwesigwa, J, Achan, J, Jawara, M, Ditanna, G, Worwui, A, Affara, M, Koukouikila-Koussounda, F, Kombo, M, Vouvoungui, C, Ntoumi, F, Etoka-Beka, MK, Deibert, J, Poulain, P, Kobawila, S, Gueye, NG, Seda, B, Kwambai, T, Jangu, P, Samuels, A, Kuile, FT, Kariuki, S, Barry, A, Bousema, T, Okech, B, Egwang, T, Corran, P, Riley, E, Ezennia, I, Ekwunife, O, Muleba, M, Stevenson, J, Mbata, K, Coetzee, M, Norris, D, Moneke-Anyanwoke, N, Momodou, J, Clarke, E, Scott, S, Tijani, A, Djimde, M, Vaillant, M, Samouda, H, Mensah, V, Roetynck, S, Kanteh, E, Bowyer, G, Ndaw, A, Oko, F, Bliss, C, Jagne, YJ, Cortese, R, Nicosia, A, Roberts, R, D'Alessio, F, Leroy, O, Faye, B, Cisse, B, Gerry, S, Viebig, N, Lawrie, A, Ewer, K, Hill, A, Nebie, I, Tiono, AB, Sanou, G, Konate, AT, Yaro, BJ, Sodiomon, S, Honkpehedji, Y, Agobe, JCD, Zinsou, F, Mengue, J, Richie, T, Hoffman, S, Nouatin, O, Ngoa, UA, Edoa, JR, Homoet, A, Engelhon, JE, Massinga-Louembe, M, Esen, M, Theisen, M, Sim, KL, Luty, AJ, Moutairou, K, Dinko, B, King, E, Targett, G, Sutherland, C, Likhovole, C, Ouma, C, Vulule, J, Musau, S, Khayumbi, J, Okumu, A, Murithi, W, Otu, J, Gehre, F, Zingue, D, Kudzawu, S, Forson, A, Mane, M, Rabna, P, Diarra, B, Kayede, S, Adebiyi, E, Kehinde, A, Onyejepu, N, Onubogu, C, Idigbe, E, Ba, A, Diallo, A, Mboup, S, Disse, K, Kadanga, G, Dagnra, Y, Baldeh, I, Corrah, T, De Jong, B, Antonio, M, Musanabaganwa, C, Musabyimana, JP, Karita, E, Diop, B, Nambajimana, A, Dushimiyimana, V, Karame, P, Russell, J, Ndoli, J, Hategekimana, T, Sendegeya, A, Condo, J, Binagwaho, A, Okonko, I, Okerentugba, P, Opaleye, O, Awujo, E, Frank-Peterside, N, Moyo, S, Kotokwe, K, Mohammed, T, Boleo, C, Mupfumi, L, Chishala, S, Gaseitsiwe, S, Tsalaile, L, Bussmann, H, Makhema, J, Baum, M, Marlink, R, Engelbretch, S, Essex, M, Novitsky, V, Saka, E, Kalipalire, Z, Bhairavabhotla, R, Midiani, D, Sherman, J, Mgode, G, Cox, C, Bwana, D, Mtui, L, Magesa, D, Kahwa, A, Mfinanga, G, Mulder, C, Borain, N, Petersen, L, Du Plessis, J, Theron, G, Holm-Hansen, C, Tekwu, EM, Sidze, LK, Assam, JPA, Eyangoh, S, Niemann, S, Beng, VP, Frank, M, Atiadeve, S, Hilmann, D, Awoniyi, D, Baumann, R, Kriel, B, Jacobs, R, Kidd, M, Loxton, A, Kaempfer, S, Singh, M, Mwanza, W, Milimo, D, Moyo, M, Kasese, N, Cheeba-Lengwe, M, Munkondya, S, Ayles, H, De Haas, P, Muyoyeta, M, Namuganga, AR, Kizza, HM, Mendy, A, Tientcheu, L, Ayorinde, A, Coker, E, Egere, U, Coussens, A, Naude, C, Chaplin, G, Noursadeghi, M, Martineau, A, Jablonski, N, Wilkinson, R, Ouedraogo, HG, Matteelli, A, Regazzi, M, Tarnagda, G, Villani, P, Sulis, G, Diagbouga, S, Roggi, A, Giorgetti, F, Kouanda, S, Bidias, A, Ndjonka, D, Olemba, C, Souleymanou, A, Mukonzo, J, Kuteesa, R, Ogwal-Okeng, J, Gustafsson, LL, Owen, J, Bassi, P, Gashau, W, Olaf, K, Dodoo, A, Okonkwo, P, Kanki, P, Maruapula, D, Seraise, B, Einkauf, K, Reilly, A, Rowley, C, Musonda, R, Framhein, A, Mpagama, S, Semvua, H, Maboko, L, Hoelscher, M, Heinrich, N, Mulenga, L, Kaayunga, C, Davies, M-A, Egger, M, Musukuma, K, Dambe, R, Usadi, B, Ngari, M, Thitiri, J, Mwalekwa, L, Fegan, G, Berkley, J, Nsagha, D, Munamunungu, V, Bolton, C, Siyunda, A, Shilimi, J, Bucciardini, R, Fragola, V, Abegaz, T, Lucattini, S, Halifom, A, Tadesse, E, Berhe, M, Pugliese, K, De Castro, P, Terlizzi, R, Fucili, L, Di Gregorio, M, Mirra, M, Zegeye, T, Binelli, A, Vella, S, Abraham, L, Godefay, H, Rakotoarivelo, R, Raberahona, M, Randriamampionona, N, Andriamihaja, R, Rasamoelina, T, Cornet, M, De Dieu Randria, MJ, Benet, T, Vanhems, P, Andrianarivelo, MR, Chirwa, U, Michelo, C, Hamoonga, R, Wandiga, S, Oduor, P, Agaya, J, Sharma, A, Cavanaugh, S, Cain, K, Mukisa, J, Mupere, E, Worodria, W, Ngom, JT, Koro, F, Godwe, C, Adande, C, Ateugieu, R, Onana, T, Ngono, A, Kamdem, Y, Ngo-Niobe, S, Etoa, F-X, Kanengoni, M, Ruzario, S, Ndebele, P, Shana, M, Tarumbiswa, F, Musesengwa, R, Gutsire, R, Fisher, K, Thyagarajan, B, Akanbi, O, Binuyo, M, Ssengooba, W, Respeito, D, Mambuque, E, Blanco, S, Mandomando, I, Cobelens, F, Garcia-Basteiro, A, Tamene, A, Topp, S, Mwamba, C, Padian, N, Sikazwe, I, Geng, E, Holmes, C, Sikombe, K, Hantuba, Czaicki, N, Simbeza, S, Somwe, P, Umulisa, M, Ilo, J, Kestelyn, E, Uwineza, M, Agaba, S, Delvaux, T, Wijgert, J, Gethi, D, Odeny, L, Tamandjou, C, Kaindjee-Tjituka, F, Brandt, L, Cotton, M, Nel, E, Preiser, W, Andersson, M, Adepoju, A, Magana, M, Etsetowaghan, A, Chilikwazi, M, Sutcliffe, C, Thuma, P, Sinywimaanzi, K, Matakala, H, Munachoonga, P, Moss, W, Masenza, IS, Geisenberger, O, Agrea, P, Rwegoshora, F, Mahiga, H, Olomi, W, Kroidl, A, Kayode, G, Amoakoh-Coleman, M, Ansah, E, Uthman, O, Fokam, J, Santoro, M-M, Musolo, C, Chimbiri, I, Chikwenga, G, Deula, R, Massari, R, Lungu, A, Perno, C-F, Ndzengue, G, Loveline, N, Lissom, A, Flaurent, T, Sosso, S, Essomba, C, Kpeli, G, Otchere, I, Lamelas, A, Buultjens, A, Bulach, D, Baines, S, Seemann, T, Giulieri, S, Nakobu, Z, Aboagye, S, Owusu-Mireku, E, Danso, E, Hauser, J, Hinic, V, Pluschke, G, Stinear, T, Yeboah-Manu, D, Elshayeb, A, Siddig, ME, Ahmed, AA, Hussien, AE, Kabwe, M, Tembo, J, Chilukutu, L, Chilufya, M, Ngulube, F, Lukwesa, C, Enne, V, Wexner, H, Mwananyanda, L, Hamer, D, Sinyangwe, S, Ahmed, Y, Klein, N, Maeurer, M, Zumla, A, Bates, M, Beyala, L, Etienne, G, Anthony, N, Benjamin, A, Ateudjieu, J, Chibwe, B, Ojok, D, Tarr, CA, Perez, GM, Omeonga, S, Kibungu, F, Meyer, A, Lansana, P, Mayor, A, Onyango, P, Van Loggerenberg, F, Furtado, T, Boggs, L, Segrt, A, Dochez, C, Burnett, R, Mphahlele, MJ, Miiro, G, Mbidde, E, Peshu, N, Kivaya, E, Ngowi, B, Kavishe, R, Maowia, M, Sandstrom, E, Ayuo, E, Mmbaga, B, Leisegang, C, Thorpe, M, Batchilly, E, N'Guessan, J-P, Kanteh, D, Søfteland, S, Sebitloane, M, Vwalika, B, Taylor, M, Galappaththi-Arachchige, H, Holmen, S, Gundersen, SG, Ndhlovu, P, Kjetland, EF, Kombe, F, Toohey, J, Pienaar, E, Kredo, T, Cham, PM, Abubakar, I, Dondeh, BL, Vischer, N, Pfeiffer, C, Burri, C, Musukwa, K, Zürcher, S, Mwandu, T, Bauer, S, Adriko, M, Mwaura, P, Omolloh, K, Jones, C, Malecela, M, Hamidu, BA, Jenner, TE, Asiedu, LJ, Osei-Atweneboana, M, Afeke, I, Addo, P, Newman, M, Durnez, L, Eddyani, M, Ammisah, N, Abas, M, Quartey, M, Ablordey, A, Akinwale, O, Adeneye, A, Ezeugwu, S, Olukosi, Y, Adewale, B, Sulyman, M, Mafe, M, Okwuzu, J, Gyang, P, Nwafor, T, Henry, U, Musa, B, Ujah, I, Agobé, JCD, Grau-Pujol, B, Sacoor, C, Nhabomba, A, Casellas, A, Quintó, L, Subirà, C, Giné, R, Valentín, A, Muñoz, J, Nikiema, M, Ky-Ba, A, Comapore, KAM, Sangare, L, Oluremi, A, Michel, M, Camara, Y, Sanneh, B, Cuamba, I, Gutiérrez, J, Lázaro, C, Mejia, R, Adedeji, A, Folorunsho, S, Demehin, P, Akinsanya, B, Cowley, G, Da Silva, ET, Nabicassa, M, De Barros, PDP, Blif, MM, Bailey, R, Last, A, Mahendradhata, Y, Gotuzzo, E, De Nys, K, Casteels, M, Nona, SK, Lumeka, K, Todagbe, A, Djima, MM, Ukpong, M, Sagay, A, Khamofu, H, Torpey, K, Afiadigwe, E, Anenih, J, Ezechi, O, Nweneka, C, Idoko, J, Muhumuza, S, Katahoire, A, Nuwaha, F, Olsen, A, Okeyo, S, Omollo, R, Kimutai, R, Ochieng, M, Egondi, T, Moonga, C, Chileshe, C, Magwende, G, Anumudu, C, Onile, O, Oladele, V, Adebayo, A, Awobode, H, Oyeyemi, O, Odaibo, A, Kabuye, E, Lutalo, T, Njua-Yafi, C, Nkuo-Akenji, T, Anchang-Kimbi, J, Mugri, R, Chi, H, Tata, R, Njumkeng, C, Dodoo, D, Achidi, E, Fernandes, J, Bache, EB, Matakala, K, Searle, K, Greenman, M, and Rainwater-Lovett, K
Published: 2017

16. Visual pathway involvement in multiple sclerosis: Look straight in the eyes

Author: Gaetani, L., Iaccheri, B., Cerquaglia, A., Gentili, L., Fiore, T., Di Gregorio, M., Mancini, A., Calabresi, P., Cagini, C., Sarchielli, P., Di Filippo, M., Calabresi P. (ORCID:0000-0003-0326-5509), Gaetani, L., Iaccheri, B., Cerquaglia, A., Gentili, L., Fiore, T., Di Gregorio, M., Mancini, A., Calabresi, P., Cagini, C., Sarchielli, P., Di Filippo, M., and Calabresi P. (ORCID:0000-0003-0326-5509)
Abstract: Visual symptoms are a common clinical manifestation of multiple sclerosis (MS) and are frequently due to acute optic neuritis (ON). However, the entire visual pathway can be involved throughout the disease course. We describe the case of a young MS patient who experienced visual symptoms that were eventually found to be caused by retinal periphlebitis, an inflammatory process of the anterior visual pathway, which is common during MS, but rarely symptomatic. This case reinforces the concept that in all MS patients complaining visual symptoms, a complete work-up should be performed in order to rule out possible ON mimicries.
Published: 2017

17. Integrating mitigation and adaptation in climate and land use policies in Brazil: a policy document analysis

Author: Di Gregorio, M, Fatorelli, L, Pramova, E, May, P, Locatelli, B, and Brockhaus, M
Subjects: P40 - Météorologie et climatologie, K01 - Foresterie - Considérations générales, A01 - Agriculture - Considérations générales, P01 - Conservation de la nature et ressources foncières
Abstract: This paper investigates climate policy integration and coherence in land use policies in Brazil. Unlike other policy analyses a key aim is to assess "internal policy coherence" in the climate change domain, or the extent to which positive and negative interactions between mitigation and adaptation are taken into account in policy formulation. The paper is based on a systematic content analysis of major federal level climate change and land use policies. The results indicate a stronger focus on climate change mitigation compared to adaptation in all land uses. Integrated approaches that consider mutually supportive mitigation and adaptation actions are called for in key climate change policies, but so far such linkages remain largely unexplored in sectoral policies. While some progress in this regard occurred in the agricultural sector, this has not translated into actual policy actions that are of use to small-scale producers. In the forest domain the focus remains almost exclusively on climate change mitigation. Three main recommendations are drawn. First, more knowledge about locally specific climate change impacts, resilience, capacity and measures for climate change adaptation is needed in order to increase the opportunities to pursue mutually beneficial approaches to climate change mitigation, adaptation and development , in particular in the forestry sector. Second, policy makers need to address more explicitly potential trade-offs between mitigation and adaptation in both policy formulation and implementation. Third, policy action on how to achieve mutually beneficial outcomes and avoid trade-offs between mitigation and adaptation needs to be operationalised into concrete policy objectives within sectoral policies and into practices that apply not just to agriculture and livestock systems, but to forested landscapes as well.
Published: 2016

18. TRPV4 mediates the calcium influx required for Flightless-non-muscle myosin interaction and collagen remodeling

Author: Arora, P. D., primary, Di Gregorio, M., additional, He, P., additional, and McCulloch, C. A., additional
Published: 2017
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19. Extracranial Venous Drainage Pattern in Multiple Sclerosis and Healthy Controls: Application of the 2011 Diagnostic Criteria for Chronic Cerebrospinal Venous Insufficiency

Author: Cardaioli, G., Di Filippo, M., Bianchi, A., Eusebi, P., Di Gregorio, M., Gaetani, L., Gallina, A., Calabresi, Paolo, Sarchielli, P., Calabresi P. (ORCID:0000-0003-0326-5509), Cardaioli, G., Di Filippo, M., Bianchi, A., Eusebi, P., Di Gregorio, M., Gaetani, L., Gallina, A., Calabresi, Paolo, Sarchielli, P., and Calabresi P. (ORCID:0000-0003-0326-5509)
Abstract: The etiology of multiple sclerosis (MS) is still largely unknown and it has been proposed that an impaired venous drainage from the central nervous system, defined as chronic cerebrospinal venous insufficiency (CCSVI), may play a role in this. We investigated the prevalence of extracranial venous drainage pattern alterations in a cohort of MS patients based on the 2011 revised diagnostic criteria for CCSVI. Thirty-nine MS patients and 18 healthy subjects underwent blinded extra-cranial venous echo-color Doppler sonography to reveal the presence of CCSVI. There was no statistically significant difference between MS patients and healthy controls regarding CCSVI prevalence (p value = 0.53). The results challenge the hypothesis that CCSVI plays a primary role in the pathogenesis of MS.
Published: 2016

20. Multiple sclerosis and chronic progressive external ophthalmoplegia associated with a large scale mitochondrial DNA single deletion

Author: Gaetani, L., Mignarri, A., Di Gregorio, M., Sarchielli, P., Malandrini, A., Cardaioli, E., Calabresi, P., Dotti, M. T., Di Filippo, M., Calabresi P. (ORCID:0000-0003-0326-5509), Gaetani, L., Mignarri, A., Di Gregorio, M., Sarchielli, P., Malandrini, A., Cardaioli, E., Calabresi, P., Dotti, M. T., Di Filippo, M., and Calabresi P. (ORCID:0000-0003-0326-5509)
Abstract: N/A
Published: 2016

21. Enabling factors for establishing REDD plus in a context of weak governance

Author: Korhonen-Kurki, K, Sehring, J, Brockhaus, M, and Di Gregorio, M
Abstract: Reducing emissions from deforestation and forest degradation (REDD+) has emerged as an important carbon governance mechanism. However, forest governance is weak in most REDD+ countries, which undermines efforts to establish REDD+. This study analyses the factors that enable national REDD+ processes in the context of weak governance using a two-step ‘qualitative comparative analysis’ (QCA) of 12 REDD+ countries. Assuming that actor-related factors can be effective only if certain institutional preconditions are met, six factors were divided into two categories that were analysed separately: institutional setting (pressure from forest-resource shortage; forest legislation, policy, and governance; already initiated policy change) and the policy arena (national ownership; transformational coalitions; inclusiveness of the policy process). The factors were analysed to determine their role in efforts to establish comprehensive REDD+ policies that target transformational change. The results reveal path dependencies and institutional stickiness in all the study countries. Only countries already undertaking institutional change have been able to establish REDD+ policies in a relatively short period – but only in the presence of either high pressure from forest-resource shortages or key features of effective forest legislation, policy, and governance. Furthermore, where an enabling institutional setting is in place, the policy arena conditions of national ownership and transformational coalitions are crucial.Policy relevance Although the aim of REDD+ is to provide performance-based payments for emissions reductions, the outcomes in terms of actual emission reductions or co-benefits are not yet observable. Most REDD+ countries are still at the design and implementation stage for policies and measures. Indicators and criteria to measure progress in this phase are required to identify which factors enable or hinder countries' performance in delivering necessary policy change to provide targeted financial incentives to support countries' efforts. This study analyses the factors that shape national REDD+ processes in the context of weak governance using a two-step QCA of 12 REDD+ countries. The results show a set of enabling conditions and characteristics of the policy process under which REDD+ policies can be established. These findings may help guide other countries seeking to formulate REDD+ policies that are likely to deliver efficient, effective, and equitable outcomes.
Published: 2014

22. Limited occurence of new grade 3-4 toxicity events with salvage regimens based on raltegravir and /or maraviroc: 96 weeks data from the ISS NIA cohort study

Author: Weimer, Le, Floridia, M., Bucciardini, R., Baroncelli, S., C M, Galluzzo, M F, Pirillo, Fragola, V., Donnini, S., Mirra, M., Di Gregorio, M., Lucattini, S., Fucili, L., Angarano, G., Ladisa, N., Volpe, A., Vullo, V., D Ettorre, G., Ceccarelli, G., Andreoni, M., Sarmati, L., Delle Rose, D., Tozzi, V., Petrosillo, N., Bellagamba, R., Libertone, R., Cicalini, S., Sighinolfi, L., Daniela Segala, Armignacco, O., Preziosi, R., Ferrari, C., Degli Antoni, A., Cavalli, A., Parruti, G., Sozio, F., Cosentino, L., Vivarelli, A., P E, Manconi, Ort, F., M L, Di Martino, Viale, P., Verrucchi, G., Tedeschi, S., M S, Mura, Mannazzu, M., Cattari, G., Tavio, M., Del Gobbo, R., Mataloni Paggi, A., Giacometti, A., Cirioni, O., Marchionni, E., Silvestri, C., Sebastianelli, S., Brescini, L., Baldelli, F., Guaraldi, Giovanni, Maria Giulia Bernardini, Stentarelli, Chiara, and Beghetto, Barbara
Subjects: maraviroc, HIV infection, raltegravir, NO
Published: 2013

23. Prevalence of antibodies anti-bartonella henselae in western sicily: children, blood donors, and cats

Author: Mansueto, P., Pepe, I., Cillari, E., Arcoleo, F., Micalizzi, A., Bonura, F., Seidita, A., Palillo, L., Di Gregorio, M., Affronti, M., Di Rosa, S., Rini, G., Vitale, G., Mansueto, P, Pepe, I, Cillari, E, Arcoleo, F, Micalizzi, A, Bonura, F, Seidita, A, Palillo, L, Di Gregorio, MF, Affronti, M, Di Rosa, S, Rini, GB, and Vitale, G
Subjects: Settore MED/09 - Medicina Interna, Bartonella henselae, childre, blood donors, cats
Published: 2012

24. Politics and power in national REDD+ policy processes

Author: Di Gregorio, M, Brockhaus, M, Cronin, T, Muharrom, E, Angelsen, A, Brockhaus, M, Sunderlin, WD, and Verchot, L
Abstract: National Strategy and Policy Options Maria Brockhaus Arild Angelsen ... depend on existing institutions and legal structures, current political and economic processes, the distribution of power and wealth, and the REDD+ actions appropriate to ...
Published: 2012

25. Lower urinary tract symptoms and urodynamic dysfunctions in clinically isolated syndromes suggestive of multiple sclerosis

Author: Di Filippo, M., Proietti, S., Ercolani, M. V., Gubbiotti, M., Di Gregorio, M., Gaetani, L., Eusebi, P., Giannantoni, A., Sarchielli, P., and Calabresi, P.
Subjects: Multiple Sclerosis, neurogenic bladder
Published: 2011

26. Neoral in liver transplant patients: Pharmacokinetic study and clinical implications

Author: Belli, L, Slim, O, De Carlis, L, Rondinara, G, Alberti, A, Zoppi, F, Bellati, G, Fesce, E, Airoldi, A, Colombo, D, Di Gregorio, M, Ideo, G, Belli, L. S., Slim, O. A., De Carlis, L., Rondinara, G. F., Alberti, A., Zoppi, F., Bellati, G., Fesce, E., Airoldi, A., Colombo, D., Di Gregorio, M., Ideo, G., Belli, L., Belli, L, Slim, O, De Carlis, L, Rondinara, G, Alberti, A, Zoppi, F, Bellati, G, Fesce, E, Airoldi, A, Colombo, D, Di Gregorio, M, Ideo, G, Belli, L. S., Slim, O. A., De Carlis, L., Rondinara, G. F., Alberti, A., Zoppi, F., Bellati, G., Fesce, E., Airoldi, A., Colombo, D., Di Gregorio, M., Ideo, G., and Belli, L.
Published: 1994

27. ISS-NIA ITALIAN COHORT: NEW ANTI-HIV INHIBITORS IN PATIENTS EXPERIENCED TO IP, NRTI, NNRTI

Author: Bucciardini, R., Floridia, M., Weimer, Le, Fragola, V., Massella, M., Baroncelli, S., Pirillo, Mf, Galluzzo, Cm, Donnini, S., Mirra, M., Di Gregorio, M., Lucattini, S., Fucili, L., Baldelli, F., Francisci, D., Martinelli, L., Bastianelli, S., Pastore, G., Ladisa, N., Volpe, A., Vullo, V., D Ettore, G., Ceccarelli, G., Andreoni, M., Sarmati, L., Delle Rose, D., Montano, M., Tozzi, V., Libertone, R., Pucillo, L., Narciso, P., Bellagamba, R., Tommasi, C., Petrosillo, N., Cicalini, S., Sighinolfi, L., Daniela Segala, Armignacco, O., Preziosi, R., Ferrari, C., Antoni, Ad, Cavalli, A., Parruti, G., Sozio, F., Cosentino, L., Dionisio, D., Vivarelli, A., Manconi, Pe, Ortu, F., Di Martino, Ml, Chiodo, F., Biagelti, C., Borderi, M., Boni, P., Del Gobbo, R., Paggi, Am, Silvestri, C., Scalise, G., Giacometti, A., Cirioni, O., Mura, Ms, Mannazzu, M., Coinu, G., Bellissima, P., Bonfante, S., Neri, D., Guaraldi, G., and Beghetto, B.
Subjects: antiretroviral therapy, HIV, COHORT STUDY, NO
Published: 2009

28. Pro-poor land tenure and democratic governance. Discussion paper No. 3.Oslo: Oslo Governance Centre

Author: Meinzen-Dick, RS, Di Gregorio, M, and Dohrn, S
Abstract: This discussion paper provides a review of how different forms of land tenure reform relate to decentralization and local governance, in theory and practice. It will guide readers who are familiar with decentralization and local governance approaches to understand the main issues and challenges posed by land tenure reforms to achieve pro-poor impact. Because land tenure reform assigns control over resources that are critical for both identity and livelihood, it will be contentious. It is, therefore, important to distinguish among four different types of land tenure reform and critically assess the political economy context and the type of decentralization as well as national-local governance relationships in which land tenure reform will be implemented. It is equally important to understand the implications of various land tenure reform types for democratic governance and social inclusion / cohesion.
Published: 2008

29. Workshop summary paper on the international conference on policy and institutional options for the management of rangelands in dry areas

Author: Ngaido, T., McCarthy, N., Di Gregorio, M., and Sustainable Agriculture and Natural Resource Management (SANREM) Knowledgebase
Subjects: Sub-Saharan Africa, North africa, Africa, Rangelands, West asia, Natural resource management, Case studies, Ecosystem Farm/Enterprise Scale Field Scale, Collective action, Community institutions, Property rights, Government institutions
Abstract: Metadata only record The system-wide program for collective action and property rights (CARPRi) sponsored an International Conference on Policy and Institutional Options for the Management of Rangelands in Dry Areas, May 7-11, 2001 in Hammamet, Tunisia. The conference focused on institutional aspects of rangeland management and brought together policy makers and researchers from North Africa, Sub-Saharan Africa and West Asia to discuss sustainable rangeland production strategies and livelihood of pastoral communities in dry areas. Available in SANREM office, FS
Published: 2002

30. Collective action and property rights for poverty reduction

Author: Mwangi, Esther, Markelova, Helen, Meinzen-Dick, Ruth, Mwangi, E ( Esther ), Markelova, H ( Helen ), Meinzen-Dick, R ( Ruth ), Di Gregorio, M, Hagedorn, K, Kirk, M, Korf, Benedikt, McCarthy, N, Swallow, B, Mwangi, Esther, Markelova, Helen, Meinzen-Dick, Ruth, Mwangi, E ( Esther ), Markelova, H ( Helen ), Meinzen-Dick, R ( Ruth ), Di Gregorio, M, Hagedorn, K, Kirk, M, Korf, Benedikt, McCarthy, N, and Swallow, B
Published: 2012

31. Private data broadcasting using digital TV and MPEG-2 transport stream

Author: Atzori, L., primary, De Natale, F.G.B., additional, Di Gregorio, M., additional, and Giusto, D.D., additional
Published: 1999
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32. Six years of experience using patient instructors to teach interviewing skills.

Author: Stillman, P L, Burpeau-Di Gregorio, M Y, Nicholson, G I, Sabers, D L, and Stillman, A E
Published: 1983
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33. Ligand interactions at the active site of aspartate transcarbamoylase from Escherichia coli

Author: Krishna Mv, William W.-C. Chan, Dennis Pr, and Di Gregorio M
Subjects: Aspartic Acid, Binding Sites, Magnetic Resonance Spectroscopy, Ligand, Stereochemistry, Macromolecular Substances, Active site, Substrate analog, Biology, Ligands, Biochemistry, chemistry.chemical_compound, Aspartate carbamoyltransferase, Kinetics, Structure-Activity Relationship, Non-competitive inhibition, chemistry, Carbamoyl phosphate, biology.protein, Side chain, Aspartate Carbamoyltransferase, Escherichia coli, Binding site, Protein Binding
Abstract: The active site of aspartate transcarbamoylase from Escherichia coli was probed by studying the inhibitory effects of substrate analogues on the catalytic subunit of the enzyme. The inhibitors were chosen to satisfy the structural requirements for binding to either the phosphate or the dicarboxylate region. In addition, they also contained a side chain that would extend into the normal position occupied by the carbamoyl group. All the compounds tested showed competitive inhibition against carbamoyl phosphate. The ionic character of the side chain was found to be highly important in determining the affinity of the inhibitor. On the other hand, very little effect on binding was produced by changing the geometry of the functional group from trigonal to tetrahedral. Our findings suggest that the electrostatic stabilization of the negative charge that develops in the transition state may be a major factor in promoting catalysis. From the available X-ray diffraction data, we propose His-134 as the residue most likely to participate in this interaction. These results have significant implications on the design of reversible and irreversible inhibitors to this enzyme.
Published: 1986

34. Electrophoresis pattern of the human platelet subpopulation proteins

Author: Nubile, G., Di Gregorio, M., Izzi, L., Luciani, S., De Cristofaro, Raimondo, Zolla, L., De Cristofaro R. (ORCID:0000-0002-8066-8849), Nubile, G., Di Gregorio, M., Izzi, L., Luciani, S., De Cristofaro, Raimondo, Zolla, L., and De Cristofaro R. (ORCID:0000-0002-8066-8849)
Abstract: In this study, the experimental conditions to perform the electrophoretic analysis of the platelet membrane's glycoproteins are described
Published: 1989

35. How do information flows affect impact from environmental research? - An analysis of a science-policy network

Author: Ferre, M, Martin-Ortega, J, Di Gregorio, M, and Dallimer, M
Subjects: Policy, Environmental Engineering, General Medicine, Management, Monitoring, Policy and Law, Waste Management and Disposal
Abstract: Evidence of the impact arising from environmental research is increasingly demanded. Exchanges between science providers and actors that use scientific knowledge to address environmental problems are recognized as a key component of the mechanisms through which impact occurs. Yet, the role of interactions between science and policy actors in delivering and shaping research impact is not well established. We aim to better understand how transfer of science in a science-policy network generates impact. Our approach relies on an exploratory social network analysis (SNA), applied to a network of organisations working on land and water management in a catchment in the UK. We analyse flows of scientific information across these organisations and how those contribute to impact, which we conceptualized as change in organisations at three levels: increased awareness, operational change and strategic change. We find that organisations occupying central positions in the network facilitate the transfer of science and influence the level of change achieved. We also find that the effectiveness of the flows of information and impact delivery depends on boundary organisations, in particular public regulatory bodies, that connect agents with others. Moreover, intended change reported by science providers does not often transform directly into change as reported by the receivers of the information. We conclude that both exchanges between researchers and research users and the role of boundary organisations are key to impact delivery and making change possible. This is valuable for understanding where improvements to information flows between organisations might enhance impact.

36. Defining the course of tumefactive multiple sclerosis: A large retrospective multicentre study

Author: Lorenzo Gaetani, Doriana Landi, Diana Ferraro, Paolo Ragonese, Alberto Gajofatto, Caterina Di Carmine, Paola Cavalla, Maria Pia Amato, Eleonora Cocco, Roberta Lanzillo, Alessia Manni, Roberta Fantozzi, Claudio Gasperini, D. Farina, Giuseppe Fenu, Sara Zagaglia, Raffaella Cerqua, Claudio Solaro, Antonio Gallo, Carolina Gabri Nicoletti, Pietro Iaffaldano, Federica Pinardi, Valentina Torri Clerici, Isabella Righini, Fabio Buttari, Damiano Paolicelli, Pietro Annovazzi, Carla Tortorella, Rocco Totaro, Giovanna De Luca, Chiara De Fino, Valentina Tomassini, Luca Prosperini, Marcello Moccia, Viviana Nociti, Maria Chiara Buscarinu, Maria Di Gregorio, Massimiliano Di Filippo, Di Gregorio M., Torri Clerici V.L.A., Fenu G., Gaetani L., Gallo A., Cavalla P., Ragonese P., Annovazzi P., Gajofatto A., Prosperini L., Landi D., Nicoletti C.G., Di Carmine C., Totaro R., Nociti V., De Fino C., Ferraro D., Tomassini V., Tortorella C., Righini I., Amato M.P., Manni A., Paolicelli D., Iaffaldano P., Lanzillo R., Moccia M., Buttari F., Fantozzi R., Cerqua R., Zagaglia S., Farina D., De Luca G., Buscarinu M.C., Pinardi F., Cocco E., Gasperini C., Solaro C.M., Di Filippo M., Di Gregorio, M., Torri Clerici, V. L. A., Fenu, G., Gaetani, L., Gallo, A., Cavalla, P., Ragonese, P., Annovazzi, P., Gajofatto, A., Prosperini, L., Landi, D., Nicoletti, C. G., Di Carmine, C., Totaro, R., Nociti, V., De Fino, C., Ferraro, D., Tomassini, V., Tortorella, C., Righini, I., Amato, M. P., Manni, A., Paolicelli, D., Iaffaldano, P., Lanzillo, R., Moccia, M., Buttari, F., Fantozzi, R., Cerqua, R., Zagaglia, S., Farina, D., De Luca, G., Buscarinu, M. C., Pinardi, F., Cocco, E., Gasperini, C., Solaro, C. M., and Di Filippo, M.
Subjects: Male, tumefactive demyelinating lesions (TDLs), 0302 clinical medicine, Retrospective Studie, Interquartile range, differential diagnosis, 030212 general & internal medicine, Prospective Studies, Young adult, Prospective cohort study, Child, treatment, Tumefactive multiple sclerosi, Tumefactive demyelinating lesions, Demyelinating Disease, Middle Aged, Magnetic Resonance Imaging, Differential diagnosis, Multiple sclerosis, Tumefactive demyelinating lesions, Tumefactive multiple sclerosis, Neurology, Multiple sclerosis, Tumefactive multiple sclerosis, Female, Human, Adult, medicine.medical_specialty, Multiple Sclerosis, Adolescent, differential diagnosi, Settore MED/26, 03 medical and health sciences, Young Adult, Oligoclonal Band, Internal medicine, medicine, Humans, Multiple sclerosi, Tumefactive multiple sclerosis (TuMS), Aged, Retrospective Studies, Tumefactive demyelinating lesion, Expanded Disability Status Scale, business.industry, Oligoclonal Bands, Retrospective cohort study, Odds ratio, medicine.disease, Confidence interval, Prospective Studie, Demyelinating Diseases, prognosis, Neurology (clinical), business, 030217 neurology & neurosurgery
Abstract: Background and purpose: Tumefactive multiple sclerosis (TuMS) (i.e., MS onset presenting with tumefactive demyelinating lesions [TDLs]) is a diagnostic and therapeutic challenge. We performed a multicentre retrospective study to describe the clinical characteristics and the prognostic factors of TuMS. Methods: One hundred two TuMS patients were included in this retrospective study. Demographic, clinical, magnetic resonance imaging (MRI), laboratory data and treatment choices were collected. Results: TuMS was found to affect women more than men (female:male: 2.4), with a young adulthood onset (median age: 29.5years, range: 11–68 years, interquartile range [IQR]: 38 years). At onset, 52% of TuMS patients presented with the involvement of more than one functional system and 24.5% of them with multiple TDLs. TDLs most frequently presented with an infiltrative MRI pattern (38.7%). Cerebrospinal fluid immunoglobulin G oligoclonal bands were often demonstrated (76.6%). In 25.3% of the cases, more than one acute-phase treatment was administered, and almost one-half of the patients (46.6%) were treated with high-efficacy treatments. After a median follow-up of 2.3years (range: 0.1–10.7 years, IQR: 3.4 years), the median Expanded Disability Status Scale (EDSS) score was 1.5 (range: 0–7, IQR: 2). Independent risk factors for reaching an EDSS score ≥3 were a higher age at onset (odds ratio [OR]: 1.08, 95% confidence interval [CI]: 1.03–1.14, p&nbsp
Published: 2021

37. Prognostic Markers of Ocrelizumab Effectiveness in Multiple Sclerosis: A Real World Observational Multicenter Study

Author: Roberta Lanzillo, Antonio Carotenuto, Elisabetta Signoriello, Rosa Iodice, Giuseppina Miele, Alvino Bisecco, Giorgia Teresa Maniscalco, Leonardo Sinisi, Felice Romano, Maria Di Gregorio, Luigi Lavorgna, Francesca Trojsi, Marcello Moccia, Mario Fratta, Nicola Capasso, Raffaele Dubbioso, Maria Petracca, Antonio Luca Spiezia, Antonio Gallo, Martina Petruzzo, Marcello De Angelis, Simona Bonavita, Giacomo Lus, Gioacchino Tedeschi, Vincenzo Brescia Morra, Lanzillo, R., Carotenuto, A., Signoriello, E., Iodice, R., Miele, G., Bisecco, A., Maniscalco, G. T., Sinisi, L., Romano, F., Di Gregorio, M., Lavorgna, L., Trojsi, F., Moccia, M., Fratta, M., Capasso, N., Dubbioso, R., Petracca, M., Spiezia, A. L., Gallo, A., Petruzzo, M., De Angelis, M., Bonavita, S., Lus, G., Tedeschi, G., Morra, V. B., Lanzillo, Roberta, Carotenuto, Antonio, Signoriello, Elisabetta, Iodice, Rosa, Miele, Giuseppina, Bisecco, Alvino, Maniscalco, Giorgia Teresa, Sinisi, Leonardo, Romano, Felice, Di Gregorio, Maria, Lavorgna, Luigi, Trojsi, Francesca, Moccia, Marcello, Fratta, Mario, Capasso, Nicola, Dubbioso, Raffaele, Petracca, Maria, Spiezia, Antonio Luca, Gallo, Antonio, Petruzzo, Martina, De Angelis, Marcello, Bonavita, Simona, Lus, Giacomo, Tedeschi, Gioacchino, and Brescia Morra, Vincenzo
Subjects: real-world, ocrelizumab, multiple sclerosi, disease-modifying treatment, progression, General Medicine, multiple sclerosis
Abstract: Pivotal trials showed the effectiveness of the monoclonal antibody ocrelizumab in relapsing and progressive multiple sclerosis (MS). However, data on everyday practice in MS patients and markers of treatment effectiveness are scarce. We aimed to collect real-world data from ocrelizumab-treated MS patients, relapsing-remitting (RR) and progressive MS patients (PMS), including active secondary progressive MS (aSPMS) and primary progressive MS (PPMS) patients, and to explore potential prognostic factors of clinical outcome. Patients were enrolled at MS centres in the Campania region, Italy. We collected clinic-demographic features retrospectively one year before ocrelizumab start (T−1), at ocrelizumab start (T0), and after one year from ocrelizumab start (T1). We explored possible clinical markers of treatment effectiveness in those patients receiving ocrelizumab treatment for at least one year using multilevel-mixed models. We included a total of 383 MS patients (89 RRMS and 294 PMS; 205 females, mean age: 45.8 ± 11.2, disease duration: 12.7 ± 11.6 years). Patients had a mean follow-up of 12.4 ± 8.2 months, and 217 patients completed one-year ocrelizumab treatment. Overall, EDSS increased from T−1 to T0 (coeff. = 0.30, 95% coefficient interval [CI] = 0.19–0.41, p < 0.001) without a further change between T0 and T1 (p = 0.61). RRMS patients did not show an EDSS change between T−1 and T0 nor between T0 and T1. Conversely, PMS patients showed EDSS increase from T−1 to T0 (coeff. = 0.34, 95% CI = 0.22–0.45, p < 0.001) without a further change between T0 and T1 (p = 0.21). PMS patients with a time from conversion shorter than 2 years showed increased EDSS from T−1 to T0 (coeff. = 0.63, 95% CI = 0.18–1.08, p = 0.006) without a further change between T0 and T1 (p = 0.94), whereas PMS patients with a time from conversion longer than 2 years showed increased EDSS from T0 to T1 (coeff. = 0.30, 95% CI = 0.11–0.49, p = 0.002). Naïve patients showed an EDSS decrease between T0 and T1 (coeff. = −0.30, 95% CI = −0.50–−0.09, p = 0.004). In conclusion, our study highlighted that early ocrelizumab treatment is effective in modifying the disability accrual in MS patients.
Published: 2022

38. Packaging and plastic are synonymous with waste: But is that really the case?

Author: Catania, Carmelina Anna, Biondo, F, La Rocca, G, Trapani, V, Trapani, F, Aliverti, M, Paura, A, Avolicino, S, Di Gregorio, M, Romano, M, Sebillo, M, Vitiello, G, Nicolosi, G, Pira, F, Lorello, L, Scaccianoce, C, Pietropaoli, S, Catania, A, Del Puglia, S, Di Dio, S, Filipi, M, Schillaci, D, Ferrara, C, Costa, M, Giunta, S, Inzerillo, B, Monterosso, F, and Catania, Carmelina Anna
Subjects: Settore ICAR/13 - Disegno Industriale, Fake news, packaging, plastic, waste, LCA, circular economy
Abstract: The paper presents the value of packaging and misconceptions about plastic. In addition to shedding light on clichés and fake news about plastic and packaging, it outlines opportunities to consider the use and management of packaging for responsible waste collection; and new forms of consumption and supply chains to facilitate the transition from the current linear consumption model to one that is more responsible and open to a circular economy.
Published: 2022

39. Environment, information, fake news. Information Disorder. Learning to Recognize Fake News. Fake News

Author: Inzerillo, Benedetto, Biondo, F, La Rocca, G, Trapani, V, Trapani, F, Aliverti, M, Paura, A, Avolicino, S, Di Gregorio, M, Romano, M, Sebillo, M, Vitiello, G, Nicolosi, G, Pira, F, Lorello, L, Scacianoce, C, Pietropaoli, S, Catania, A, Del Puglia, S, Di Dio, S, Filipi, M, Schillaci, D, Ferrara, C, Costa, M, Giunta, S, Inzerillo, B, Monterosso, F, and Inzerillo, Benedetto
Subjects: Sustainability, manipulation, communication, ecology, nature, Settore ICAR/13 - Disegno Industriale
Abstract: Although more than 25 years have passed since the publication of a report that clearly shows the scientific evidence on global warming and the influence of human activity, today there are still thousands of fake news stories circulating on the web. Lobbies have always used the media to discredit science, and with the boom in social media this strategy has shifted online. Deniers single out items of scientific truth and use them instrumentally to render fake news credible. After years of a widespread lack of control, something is changing: since 2020, Facebook has created the "Climate Science Information Center", a platform that signals fake climate news and encourages people to consult official and reliable sources. What can we Designers do? One of the main causes of the climate crisis is the production of carbon dioxide: planting a thousand billion trees would seem to be the most efficient and ecological solution right now. Reforestation or urban forestation projects are giving us time to think about an ecological transition plan. Our primary goal must be urban models steeped in nature, reduction of waste production and pollution, reduction of energy consumption and projects that employ plants to purify the air.
Published: 2022

40. From the Panopticon to the freedom to communicate in the city space

Author: Trapani, Ferdinando, Biondo, F, La Rocca, G, Trapani, V, Trapani, F., Aliverti, M., Paura, A., Avolicino, S., Di Gregorio, M., Romano, M., Sebillo, M., Vitiello, G., La Rocca, G., Nicolosi, G., Pira, F., Biondo, F., Lorello, L., Scacianoce, C., Pietropaoli, S., Catania, A., Del Puglia, S., Di Dio, S., Filipi, M., Schillaci, D., Ferrara, C., Costa, M., Giunta, S., Inzerillo, B., Monterosso, F., Trapani, V., and Trapani, Ferdinando
Subjects: Media, urban &amp, regional planning, ideology, public opinion, technologies of power, ICT, Settore ICAR/21 - Urbanistica
Abstract: The aim of this article is to explore the possible link existing between space, particularly city space, and disinformation. The examination of some points of transition and change in the structure of technologies and their exploitation by power systems and power games will help identify some of their characteristics, namely control, domination and defence. The urban and territorial spatial dimension is a relational environment produced in various ways by the government practices and policies of a city. Transformations of the city space are set in motion by decision- making power, and these in turn are dependent on public opinion, which can be influenced in various ways by forms of disinformation. Citizens seek to trace the truth of information and therefore demand assurance from decision makers that their communication actions are anchored in reality. The state does not seem to be able to provide these guarantees due to the social transformation brought about by the profound change in communication instruments. In the conclusions, the study stresses the urgency to research into the links between city space and communicative action under conditions in which the phenomena of information distortion are controlled and assessed also with the aid of information technologies implemented to challenge the complexity of the exponential growth of data used as the basis for building public opinion without which no planning effort is possible.
Published: 2022

41. Supramolecular assembly of a thermoresponsive steroidal surfactant with an oppositely charged thermoresponsive block copolymer

Author: J. Vázquez Tato, Nicolae Viorel Pavel, Francisco Meijide, M. C. di Gregorio, S. De Santis, Marta Gubitosi, Luciano Galantini, Simona Sennato, F. Tranchini, Aida Jover, Karin Schillén, Giancarlo Masci, Leana Travaglini, di Gregorio, M C, Gubitosi, M, Travaglini, L, Pavel, N V, Jover, A, Meijide, F, Vázquez Tato, J, Sennato, S, Schillén, K, Tranchini, F, De Santis, S, Masci, G, and Galantini, L
Subjects: Circular dichroism, Chemistry, Supramolecular chemistry, Cationic polymerization, General Physics and Astronomy, block copolymer, 02 engineering and technology, self-assembly, sodium cholate, 010402 general chemistry, 021001 nanoscience & nanotechnology, thermoresponsive materials, 01 natural sciences, Micelle, 0104 chemical sciences, Supramolecular assembly, Polymer chemistry, Amphiphile, Copolymer, supramolecular, thermoresponsive, Soft matter, Physical and Theoretical Chemistry, 0210 nano-technology
Abstract: Supramolecular rearrangements are crucial in determining the response of stimuli sensitive soft matter systems such as those formed by mixtures of oppositely charged amphiphiles. Here mixtures of this kind were prepared by mixing the cationic block copolymer pAMPTMA(30)-b-pNIPAAM(120) and an anionic surfactant obtained by the modification of the bile salt sodium cholate. As pure components, the two compounds presented a thermoresponsive self-assembly at around 30-35 degrees C; a micelle formation in the case of the copolymer and a transition from fibers to tubes in the case of the bile salt derivative. When both were present in the same solution they associated into mixed aggregates that showed complex thermoresponsive features. At room temperature, the core of the aggregate was comprised of a supramolecular twisted ribbon of the bile salt derivative. The block copolymers were anchored on the surface of this ribbon through electrostatic interactions between their charged blocks and the oppositely charged heads of the bile salt molecules. The whole structure was stabilized by a corona of the uncharged blocks that protruded into the surrounding solvent. By increasing the temperature to 30-34 degrees C the mixed aggregates transformed into rods with smooth edges that associated into bundles and clusters, which in turn induced clouding of the solution. Circular dichroism allowed us to follow progressive rearrangements of the supramolecular organization within the complex, occurring in the range of temperature of 20-70 degrees C.
Published: 2016
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42. GENDER DIFFERENCES IN HCV CHRONIC LIVER DISEASE: A REAL LIFE EVALUATION IN PITER (PIATTAFORMA ITALIANA PER LO STUDIO DELLA TERAPIA DELLE EPATITI VIRALI) COHORT STUDY

Author: M. Puoti, G.B. Gaeta, T. Santantonio, Francesco Paolo Russo, Silvia Fargion, M. Siciliano, M. Di Gregorio, Salvatore Madonia, Pierluigi Toniutto, D. Ieluzzi, Loredana Falzano, Giuseppe Montalto, Luchino Chessa, Giuseppe Foti, Adriano Lazzarin, Gianpiero D'Offizi, Carmine Coppola, Gloria Taliani, Claudio Viscoli, Massimo Zuin, Maria Rendina, Antonio Craxì, Al Zignego, Giovanni Raimondo, V. De Maria, E.M. Erne, Mario Strazzabosco, Adele Giammario, M. Colombo, P. Andreone, Claudio Maria Mastroianni, Alessandro Federico, G. Angarano, Andrea Giacometti, Maria Cristina Vinci, Antonio Benedetti, Carlo Ferrari, Erica Villa, Floriano Rosina, Marcello Persico, G. Nardone, Marco Massari, M. Rumi, Liliana Chemello, Gabriella Verucchi, Ivan Gentile, M.G. Quaranta, Loreta A. Kondili, Guglielmo Borgia, M. Andreoni, Stefano Vella, Antonio Gasbarrini, Maurizia Rossana Brunetto, Pierluigi Blanc, Alessia Ciancio, Alfredo Alberti, Carlo Torti, A. Di Leo, Nicola Caporaso, Kondili, L, Quaranta, Mg, Falzano, L, Di Gregorio, M, Brunetto, M, Zignego, Al, Ciancio, A, Di Leo, A, Rendina, M, Raimondo, G, Ferrari, C, Craxi, A, Taliani, G, Borgia, Guglielmo, Gentile, Ivan, Santantonio, Ta, Giammario, A, Blanc, P, Gaeta, Gb, Gasbarrini, A, Siciliano, M, Chessa, L, Erne, Em, Ieluzzi, D, Russo, Fp, Andreone, P, Vinci, M, Coppola, C, Chemello, L, Madonia, S, Verucchi, G, Persico, M, Zuin, M, Alberti, A, Puoti, M, Nardone, G, De Maria, V, Massari, M, Montalto, G, Foti, G, Rumi, Mg, Giacometti, A, Benedetti, A, D'Offizi, G, Strazzabosco, M, Fargion, S, Angarano, G, Federico, A, Caporaso, Nicola, Mastroianni, C, Toniutto, P, Colombo, M, Lazzarin, A, Torti, C, Andreoni, M, Rosina, F, Viscoli, C, Vella, S, and Villa, E.
Subjects: 030203 arthritis & rheumatology, medicine.medical_specialty, Hepatology, business.industry, Chronic liver disease, medicine.disease, Surgery, 03 medical and health sciences, 0302 clinical medicine, Life evaluation, Internal medicine, medicine, 030211 gastroenterology & hepatology, business, Studio, Cohort study
Published: 2016

43. Performance of Ground Anchors Built in a Flysch Deposit

Author: Gianfranco Urciuoli, Aldo Minardo, Luciano Picarelli, Luigi Zeni, Maria Cristina Di Gregorio, Raffaele Papa, Di Gregorio, M. C. ., Papa, R., Urciuoli, Gianfranco, Picarelli, L., Zeni, L., and Minardo, A.
Subjects: Anchor, Flysch, Lateral surface, Soil test, Grout, Effective stress, 0211 other engineering and technologies, Earth and Planetary Sciences(all), 02 engineering and technology, General Medicine, engineering.material, 010502 geochemistry & geophysics, skin friction, 01 natural sciences, stabilization, slope stability, Earth anchor, Slope stability, Ultimate tensile strength, engineering, Geotechnical engineering, Geology, 021101 geological & geomatics engineering, 0105 earth and related environmental sciences
Abstract: The ultimate pull-out tensile load of ground anchors is strongly dependent onsoil nature,grout injection and effective stress state around the bulb. In this paper, the comparison between the results of conventional pull-out testson instrumented anchors built in a flysch formation and those of small scale pull-out tests performed in the laboratory,on undisturbed soil samples recovered at the depth of the anchor bulb,allowed to closely examine the skin friction that can be mobilizedin undrained conditionsat the soil-structure interface. The experiments highlight a strong scale effect, probably depending on the real size androughness ofthe lateral surface of the bulb. In fact, theirregular bulb profiledue to flysch features strongly contributes to the pull-outstrength.
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44. Galectin-3/Gelatin Electrospun Scaffolds Modulate Collagen Synthesis in Skin Healing but Do Not Improve Wound Closure Kinetics.

Author: McLeod KA, Di Gregorio M, Tinney D, Carmichael J, Zuanazzi D, Siqueira WL, Rizkalla A, and Hamilton DW
Abstract: Chronic wounds remain trapped in a pro-inflammatory state, with strategies targeted at inducing re-epithelialization and the proliferative phase of healing desirable. As a member of the lectin family, galectin-3 is implicated in the regulation of macrophage phenotype and epithelial migration. We investigated if local delivery of galectin-3 enhanced skin healing in a full-thickness excisional C57BL/6 mouse model. An electrospun gelatin scaffold loaded with galectin-3 was developed and compared to topical delivery of galectin-3. Electrospun gelatin/galectin-3 scaffolds had an average fiber diameter of 200 nm, with 83% scaffold porosity approximately and an average pore diameter of 1.15 μm. The developed scaffolds supported dermal fibroblast adhesion, matrix deposition, and proliferation in vitro. In vivo treatment of 6 mm full-thickness excisional wounds with gelatin/galectin-3 scaffolds did not influence wound closure, re-epithelialization, or macrophage phenotypes, but increased collagen synthesis. In comparison, topical delivery of galectin-3 [6.7 µg/mL] significantly increased arginase-I cell density at day 7 versus untreated and gelatin/galectin-3 scaffolds ( p < 0.05). A preliminary assessment of increasing the concentration of topical galectin-3 demonstrated that at day 7, galectin-3 [12.5 µg/mL] significantly increased both epithelial migration and collagen content in a concentration-dependent manner. In conclusion, local delivery of galectin 3 shows potential efficacy in modulating skin healing in a concentration-dependent manner.
Published: 2024
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45. Fosfomycin-Containing Regimens for the Treatment of Central Nervous System Infections in a Neonatal Intensive Care Unit: A Case Series Study.

Author: Lenzi A, Saccani B, Di Gregorio M, Rossini F, Sollima A, Mulè A, Morucci F, Amadasi S, Fumarola B, Lanza PA, Lorenzotti S, Van Hauwermeiren E, Cavalleri E, Marzollo R, Matteelli A, Signorini L, and Risso FM
Abstract: Central nervous system infections are among the most severe infectious conditions in the neonatal period and are still burdened by significant mortality, especially in preterm infants and those with a low birth weight or other comorbidities. In this study, we examined the role of fosfomycin-containing antibiotic regimens in neonates with central nervous system infections. We included six neonates over a period of five years: four with meningitis and two with cerebral abscesses. All patients underwent fosfomycin therapy after failing first-line antibiotic regimens. Of the six neonates, two died; two developed neurological and psychomotor deficits and two recovered uneventfully. None of the neonates experienced adverse reactions to fosfomycin, confirming the safety of the molecule in this population. In conclusion, the deep penetration in the central nervous system, the unique mechanism of action, the synergy with other antibiotic therapies, and the excellent safety profile all make fosfomycin an attractive drug for the treatment of neonatal central nervous system infections.
Published: 2024
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46. Four years monitoring of the endangered European plethodontid salamanders.

Author: Coppari L, Di Gregorio M, Corti C, Merilli S, Mulargia M, Cogoni R, Manenti R, Ficetola GF, and Lunghi E
Subjects: Animals, Europe, Biodiversity, Climate Change, Urodela, Endangered Species, Conservation of Natural Resources
Abstract: The ongoing biodiversity crisis is strongly threatening amphibians, mostly because of their peculiar physiology, their sensitivity to climate change and the spread of diseases. Effective monitoring involving assessments of pressure effects across time and estimation of population trends play a key role in mitigating amphibian decline. To improve implementation of standardized protocols and conservation efforts, we present here a dataset related to one of the amphibian genera whose onservation status is considered the most declining according to the IUCN. We report information on 66 populations of the endangered European cave salamanders, genus Speleomantes, that was collected through a standardized monitoring along a four-year period (2021-2024). Demographics data of the populations and fitness-related data of single individuals are reported. Furthermore, we include 3,836 high quality images of individuals that can allow to perform studies aiming to assess the phenotypic variability within the genus, and to perform long-term capture-mark-recaptured studies., (© 2024. The Author(s).)
Published: 2024
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47. A Rare Case of Multidrug-resistant Leclercia adecarboxylata Catheter-related Bloodstream Infection and an Updated Brief Literature Review.

Author: Colangelo C, Tiecco G, Di Gregorio M, Capone S, Allegri RL, De Francesco M, Caccuri F, Caruso A, Castelli F, and Focà E
Abstract: Competing Interests: Competing interests: The authors declare no conflict of Interest.
Published: 2023
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48. Case report: An occult hepatitis B virus infection reactivation in an HIV/HCV coinfected patient during an immune reconstitution inflammatory syndrome.

Author: Zaltron S, Cambianica A, Di Gregorio M, Colangelo C, Storti S, Tiecco G, Castelli F, and Quiros-Roldan E
Subjects: Humans, Hepatitis B virus physiology, Antiviral Agents therapeutic use, Symptom Flare Up, DNA, Viral genetics, Hepatitis B, Chronic, Coinfection drug therapy, Immune Reconstitution Inflammatory Syndrome diagnosis, Immune Reconstitution Inflammatory Syndrome drug therapy, HIV Infections complications, HIV Infections drug therapy, Hepatitis C, Chronic drug therapy, Hepatitis B complications, Hepatitis B diagnosis, Hepatitis B drug therapy
Abstract: The natural history of occult hepatitis B virus infection (OBI) and the mechanism involved in HBV reactivation are only partially understood. As regards people living with HIV (PLWH), HBV reactivation is estimated to occur with an incidence ratio of 0.019 cases per 100 person-year. Here we report the case of OBI reactivation in a HIV/HCV co-infected patient followed for 25 years at our Infectious Diseases Unit, but, unfortunately, lost to follow-up about 19 months after Direct-acting antivirals (DAAs) treatment. At re-engagement, blood tests showed high replication of plasmatic HIV-RNA along with severe immunosuppression and normal levels of liver enzymes. However, 3 months after ART reintroduction, an immune reconstitution inflammatory syndrome (IRIS) was diagnosed with high detectable HBV-DNA load and transaminase elevation. Our case report shows how the balance between the virus and the host immune system is quite a dynamic process that might significantly impact the course of the disease. The aim of this case report is to bring to the attention of physicians that, although OBI reactivation is a rather rare occurrence, even amongst PLWH, its potential consequences compel to a high alertness on the matter. Therefore, especially in patients with an impaired immune system and on a tenofovir or lamivudine-sparing regimen, HBV serological and virological markers should always be strictly monitored, even in the absence of a hepatitis flare., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Zaltron, Cambianica, Di Gregorio, Colangelo, Storti, Tiecco, Castelli and Quiros-Roldan.)
Published: 2023
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49. Exploring the use of WeChat for qualitative social research: The case of Italian digital diaspora in Shanghai.

Author: Moffa G and Di Gregorio M
Abstract: The widespread use of digital communication technologies has created new opportunities for social research. In this paper, we explore the limits and potentials of using messaging and social media apps as tools for qualitative research. Building upon our research on Italian migration to Shanghai, we discuss in detail the methodological choice of using WeChat for teamwork, remote sampling strategies, and conducting interviews. The paper highlights the benefits that researchers may have from employing the same technology that the studied community uses in their daily life as a research tool, and advocates for a flexible approach to research that adapts its tools and methods to the specific requirements and characteristics of the fieldwork. In our case, this strategy allowed us to emphasize that WeChat represents a digital migratory space which played a crucial role in understanding and making of the Italian digital diaspora in China., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Moffa and Di Gregorio.)
Published: 2023
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50. Monitoring of the Endangered Cave Salamander Speleomantes sarrabusensis .

Author: Cogoni R, Di Gregorio M, Cianferoni F, and Lunghi E
Abstract: In this study, we performed the first monitoring activities on one of the most endangered amphibians in Europe, the Sette Fratelli cave salamander Speleomantes sarrabusensis . The data presented here are derived from two monitoring activities aiming to assess the status and abundance of four populations of S. sarrabusensis . With the first monitoring, we surveyed the well-known population occurring within artificial springs during the period 2015-2018, providing monthly data on the number of active individuals. With the second monitoring performed during spring to early summer of 2022, we surveyed four populations at three time points (the one from artificial springs and three from forested areas) and we provided the first estimation of the populations' abundance. Furthermore, we analyzed for the first time the stomach contents from a population of S. sarrabusensis only occurring in forested environments. With our study, we provided the first information on the abundance of different populations of S. sarrabusensis , representing the starting point for future status assessments for this endangered species.
Published: 2023
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