31 results on '"Delgado-Bolton, R."'
Search Results
2. Joint EANM/SNMMI/ESTRO practice recommendations for the use of 2‑[18F]FDG PET/CT external beam radiation treatment planning in lung cancer V1.0
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Vaz, S., Adam, J., Delgado Bolton, R., Vera, P., Elmpt, W., Herrmann, K., Hicks, R., Lievens, Y., Santos, A., Schöder, H., Dubray, B., Visvikis, D., (0000-0001-9550-9050) Troost, E. G. C., Geus-Oei, L., Vaz, S., Adam, J., Delgado Bolton, R., Vera, P., Elmpt, W., Herrmann, K., Hicks, R., Lievens, Y., Santos, A., Schöder, H., Dubray, B., Visvikis, D., (0000-0001-9550-9050) Troost, E. G. C., and Geus-Oei, L.
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Purpose 2-[18F]FDGPET/CT is of utmost importance for radiation treatment (RT) planning and response monitoring in lung cancer patients, in both non-small and small cell lung cancer (NSCLC and SCLC). This topic has been addressed in guidelines composed by experts within the feld of radiation oncology. However, up to present, there is no procedural guideline on this subject, with involvement of the nuclear medicine societies. Methods A literature review was performed, followed by a discussion between a multidisciplinary team of experts in the different fields involved in the RT planning of lung cancer, in order to guide clinical management. The project was led by experts of the two nuclear medicine societies (EANM and SNMMI) and radiation oncology (ESTRO). Results and conclusion This guideline results from a joint and dynamic collaboration between the relevant disciplines for this topic. It provides a worldwide, state of the art, and multidisciplinary guide to 2-[18F]FDG PET/CT RT planning in NSCLC and SCLC. These practical recommendations describe applicable updates for existing clinical practices, highlight potential faws, and provide solutions to overcome these as well. Finally, the recent developments considered for future application are also reviewed.
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- 2022
3. The “3M” Approach to Cardiovascular Infections: Multimodality, Multitracers, and Multidisciplinary
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Sollini, M, Berchiolli, R, Delgado Bolton, R, Rossi, A, Kirienko, M, Boni, R, Lazzeri, E, Slart, R, Erba, P, Sollini M., Berchiolli R., Delgado Bolton R. C., Rossi A., Kirienko M., Boni R., Lazzeri E., Slart R., Erba P. A., Sollini, M, Berchiolli, R, Delgado Bolton, R, Rossi, A, Kirienko, M, Boni, R, Lazzeri, E, Slart, R, Erba, P, Sollini M., Berchiolli R., Delgado Bolton R. C., Rossi A., Kirienko M., Boni R., Lazzeri E., Slart R., and Erba P. A.
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Cardiovascular infections are associated with high morbidity and mortality. Early diagnosis is crucial for adequate patient management, as early treatment improves the prognosis. The diagnosis cannot be made on the basis of a single symptom, sign, or diagnostic test. Rather, the diagnosis requires a multidisciplinary discussion in addition to the integration of clinical signs, microbiology data, and imaging data. The application of multimodality imaging, including molecular imaging techniques, has improved the sensitivity to detect infections involving heart valves and vessels and implanted cardiovascular devices while also allowing for early detection of septic emboli and metastatic infections before these become clinically apparent. In this review, we describe data supporting the use of a Multimodality, Multitracer, and Multidisciplinary approach (the 3M approach) to cardiovascular infections. In particular, the role of white blood cell SPECT/CT and [18F]FDG PET/CT in most prevalent and clinically relevant cardiovascular infections will be discussed. In addition, the needs of advanced hybrid equipment, dedicated imaging acquisition protocols, specific expertise for image reading, and interpretation in this field are discussed, emphasizing the need for a specific reference framework within a Cardiovascular Multidisciplinary Team Approach to select the best test or combination of tests for each specific clinical situation.
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- 2018
4. ECCO essential requirements for quality cancer care: Oesophageal and gastric cancer
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Allum, W, Lordick, F, Alsina, M, Andritsch, E, Ba-Ssalamah, A, Beishon, M, Braga, M, Caballero, C, Carneiro, F, Cassinello, F, Dekker, J, Delgado-Bolton, R, Haustermans, K, Henning, G, Hutter, B, Lovey, J, Netikova, I, Obermannova, R, Oberst, S, Rostoft, S, Saarto, T, Seufferlein, T, Sheth, S, Wynter-Blyth, V, Costa, A, Naredi, P, Allum W., Lordick F., Alsina M., Andritsch E., Ba-Ssalamah A., Beishon M., Braga M., Caballero C., Carneiro F., Cassinello F., Dekker J. W., Delgado-Bolton R., Haustermans K., Henning G., Hutter B., Lovey J., Netikova I., Obermannova R., Oberst S., Rostoft S., Saarto T., Seufferlein T., Sheth S., Wynter-Blyth V., Costa A., Naredi P., Allum, W, Lordick, F, Alsina, M, Andritsch, E, Ba-Ssalamah, A, Beishon, M, Braga, M, Caballero, C, Carneiro, F, Cassinello, F, Dekker, J, Delgado-Bolton, R, Haustermans, K, Henning, G, Hutter, B, Lovey, J, Netikova, I, Obermannova, R, Oberst, S, Rostoft, S, Saarto, T, Seufferlein, T, Sheth, S, Wynter-Blyth, V, Costa, A, Naredi, P, Allum W., Lordick F., Alsina M., Andritsch E., Ba-Ssalamah A., Beishon M., Braga M., Caballero C., Carneiro F., Cassinello F., Dekker J. W., Delgado-Bolton R., Haustermans K., Henning G., Hutter B., Lovey J., Netikova I., Obermannova R., Oberst S., Rostoft S., Saarto T., Seufferlein T., Sheth S., Wynter-Blyth V., Costa A., and Naredi P.
- Abstract
Background: ECCO essential requirements for quality cancer care (ERQCC) are checklists and explanations of organisation and actions that are necessary to give high-quality care to patients who have a specific type of cancer. They are written by European experts representing all disciplines involved in cancer care. ERQCC papers give oncology teams, patients, policymakers and managers an overview of the elements needed in any healthcare system to provide high quality of care throughout the patient journey. References are made to clinical guidelines and other resources where appropriate, and the focus is on care in Europe. Oesophageal and gastric: essential requirements for quality care: • Oesophageal and gastric (OG) cancers are a challenging tumour group with a poor prognosis and wide variation in outcomes among European countries. Increasing numbers of older people are contracting the diseases, and treatments and care pathways are becoming more complex in both curative and palliative settings.• High-quality care can only be a carried out in specialised OG cancer units or centres which have both a core multidisciplinary team and an extended team of allied professionals, and which are subject to quality and audit procedures. Such units or centres are far from universal in all European countries.• It is essential that, to meet European aspirations for comprehensive cancer control, healthcare organisations implement the essential requirements in this paper, paying particular attention to multidisciplinarity and patient-centred pathways from diagnosis, to treatment, to survivorship. Conclusion: Taken together, the information presented in this paper provides a comprehensive description of the essential requirements for establishing a high-quality OG cancer service. The ERQCC expert group is aware that it is not possible to propose a ‘one size fits all’ system for all countries, but urges that access to multidisciplinary units or centres must be guaranteed for all those w
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- 2018
5. FDG-PET/CT(A) imaging in large vessel vasculitis and polymyalgia rheumatica: joint procedural recommendation of the EANM, SNMMI, and the PET Interest Group (PIG), and endorsed by the ASNC
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Slart, R. H. J. A., Glaudemans, A. W. J. M., Chareonthaitawee, P., Treglia, G., Besson, F. L., Bley, T. A., Blockmans, D., Boellaard, R., Bucerius, J., Carril, J. M., Chen, W., Cid, M. C., Dagupta, B., Dorbala, S., Gheysens, O., Hyafil, F., Jain, S., Klink, T., van der Laken, C. J., Lomena, F., Massollo, M., Prieto-Gonzalez, S., Luqmani, R., Roivainen, A., Salvarani, C., Saraste, A., Schirmer, M., Verberne, H. J., Versari, A., Voskuyl, A. E., Walter, M. A., Camellino, D., Brouwer, E., Cimmino, M. A., Abidov, A., Agostini, D., Beanlands, R. S., Delgado-Bolton, R. C., Einstein, A. J., Gimelli, A., Miller, E. J., Sciagra, R., and Signore, A.
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musculoskeletal diseases ,medicine.medical_specialty ,Giant Cell Arteritis ,Disease ,Review Article ,DISEASE-ACTIVITY ,030218 nuclear medicine & medical imaging ,Polymyalgia rheumatica ,03 medical and health sciences ,POSITRON-EMISSION-TOMOGRAPHY ,0302 clinical medicine ,GIANT-CELL ARTERITIS ,Fluorodeoxyglucose F18 ,Large vessel vasculitis ,Positron Emission Tomography Computed Tomography ,Imaging procedure ,Medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,030203 arthritis & rheumatology ,FDG-PET/CT(A) ,medicine.diagnostic_test ,business.industry ,ABATACEPT CTLA-4IG ,SEMIQUANTITATIVE ANALYSIS ,TAKAYASU ARTERITIS ,EARLY-DIAGNOSIS ,General Medicine ,medicine.disease ,DOUBLE-BLIND TRIAL ,Functional imaging ,Giant cell arteritis ,Positron emission tomography ,Polymyalgia Rheumatica ,Positron-Emission Tomography ,Public Opinion ,Interest group ,Angiography ,F-18 FDG-PET/CT ,Radiology ,FOLLOW-UP ,business - Abstract
Large vessel vasculitis (LVV) is defined as a disease mainly affecting the large arteries, with two major variants, Takayasu arteritis (TA) and giant cell arteritis (GCA). GCA often coexists with polymyalgia rheumatica (PMR) in the same patient, since both belong to the same disease spectrum. FDG-PET/CT is a functional imaging technique which is an established tool in oncology, and has also demonstrated a role in the field of inflammatory diseases. Functional FDG-PET combined with anatomical CT angiography, FDG-PET/CT(A), may be of synergistic value for optimal diagnosis, monitoring of disease activity, and evaluating damage progression in LVV. There are currently no guidelines regarding PET imaging acquisition for LVV and PMR, even though standardization is of the utmost importance in order to facilitate clinical studies and for daily clinical practice. This work constitutes a joint procedural recommendation on FDG-PET/CT(A) imaging in large vessel vasculitis (LVV) and PMR from the Cardiovascular and Inflammation & Infection Committees of the European Association of Nuclear Medicine (EANM), the Cardiovascular Council of the Society of Nuclear Medicine and Molecular Imaging (SNMMI), and the PET Interest Group (PIG), and endorsed by the American Society of Nuclear Cardiology (ASNC). The aim of this joint paper is to provide recommendations and statements, based on the available evidence in the literature and consensus of experts in the field, for patient preparation, and FDG-PET/CT(A) acquisition and interpretation for the diagnosis and follow-up of patients with suspected or diagnosed LVV and/or PMR. This position paper aims to set an internationally accepted standard for FDG-PET/CT(A) imaging and reporting of LVV and PMR. Electronic supplementary material The online version of this article (10.1007/s00259-018-3973-8) contains supplementary material, which is available to authorized users.
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- 2018
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6. Empatía, habilidades de colaboración interprofesional y aprendizaje médico permanente en residentes españoles y latinoamericanos que inician los programas de formación médica especializada en España. Resultados preliminares = Medical empathy of physicians-in-training who are enrolled in professional training programs. A comparative intercultural study in Spain
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Delgado-Bolton, R., San-Martín, M., Alcorta-Garza, A., and Vivanco, L.
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Physicians ,Cross-cultural comparison ,Teaching hospital ,Empathy ,Foreign medical graduates - Abstract
Objective: To characterise some of the environmental factors that are sensitive to cultural influence, and are involved in the development of medical empathy in Spanish and Latin American physicians-in-training. Design: Cross-sectional study using questionnaires. Setting: Primary care and specialized medicine centres of the Healthcare System of La Rioja, Logroño, Spain. Participants: Physicians-in-training. Main measurements:: Empathy was measured using the Jefferson Scale of Physician Empathy, version for healthcare professionals (JSE-HP). Socio-demographic, academic, and professional background information was collected. Results: A total of 104 residents (67 from Spain and 32 from Latin America) answered and returned the questionnairess. The JSE-HP showed adequate psychometric properties. The empathy mean score of Spanish group was higher than that of the Latin American group (P=.01). Differences in the development of empathy were associated with: the development of professional models (P
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- 2015
7. ECCO Essential Requirements for Quality Cancer Care: Soft Tissue Sarcoma in Adults and Bone Sarcoma. A critical review
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Andritsch, E, Beishon, M, Bielack, S, Bonvalot, S, Casali, P, Crul, M, Delgado-Bolton, R, Donati, D, Douis, H, Haas, R, Hogendoorn, P, Kozhaeva, O, Lavender, V, Lovely, J, Negrouk, A, Pereira, P, Roca, P, Rochette de Lempdes, G, Saarto, T, van Berck, B, Vassal, G, Wartenberg, M, Yared, W, Costa, A, Naredi, P, Andritsch, E, Beishon, M, Bielack, S, Bonvalot, S, Casali, P, Crul, M, Delgado-Bolton, R, Donati, D, Douis, H, Haas, R, Hogendoorn, P, Kozhaeva, O, Lavender, V, Lovely, J, Negrouk, A, Pereira, P, Roca, P, Rochette de Lempdes, G, Saarto, T, van Berck, B, Vassal, G, Wartenberg, M, Yared, W, Costa, A, and Naredi, P
- Abstract
ECCO essential requirements for quality cancer care (ERQCC) are checklists and explanations of organisation and actions that are necessary to give high-quality care to patients who have a specific tumour type. They are written by European experts representing all disciplines involved in cancer care. ERQCC papers give oncology teams, patients, policymakers and managers an overview of the elements needed in any healthcare system to provide high quality of care throughout the patient journey. References are made to clinical guidelines and other resources where appropriate, and the focus is on care in Europe. Sarcoma: essential requirements for quality care • Sarcomas – which can be classified into soft tissue and bone sarcomas – are rare, but all rare cancers make up more than 20% of cancers in Europe, and there are substantial inequalities in access to high-quality care. Sarcomas, of which there are many subtypes, comprise a particularly complex and demanding challenge for healthcare systems and providers. This paper presents essential requirements for quality cancer care of soft tissue sarcomas in adults and bone sarcomas. • High-quality care must only be carried out in specialised sarcoma centres (including paediatric cancer centres) which have both a core multidisciplinary team and an extended team of allied professionals, and which are subject to quality and audit procedures. Access to such units is far from universal in all European countries. • It is essential that, to meet European aspirations for high-quality comprehensive cancer control, healthcare organisations implement the requirements in this paper, paying particular attention to multidisciplinarity and patient-centred pathways from diagnosis and follow-up, to treatment, to improve survival and quality of life for patients. Conclusion Taken together, the information presented in this paper provides a comprehensive description of the essential requirements for establishing a high-quality service for soft t
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- 2016
8. FDG PET/CT: EANM procedure guidelines for tumour imaging: version 2.0
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Boellaard, R., Delgado-Bolton, R., Oyen, W.J.G., Giammarile, F., Tatsch, K., Eschner, W., Verzijlbergen, F.J., Barrington, S.F., Pike, L.C., Weber, W.A., Stroobants, S., Delbeke, D., Donohoe, K.J., Holbrook, S., Graham, M.M., Testanera, G., Hoekstra, O.S., Zijlstra, J., Visser, E., Hoekstra, C.J., Pruim, J., Willemsen, A., Arends, B., Kotzerke, J.o., ,rg, Bockisch, A., Beyer, T., Chiti, A., Krause, B.J., Boellaard, R., Delgado-Bolton, R., Oyen, W.J.G., Giammarile, F., Tatsch, K., Eschner, W., Verzijlbergen, F.J., Barrington, S.F., Pike, L.C., Weber, W.A., Stroobants, S., Delbeke, D., Donohoe, K.J., Holbrook, S., Graham, M.M., Testanera, G., Hoekstra, O.S., Zijlstra, J., Visser, E., Hoekstra, C.J., Pruim, J., Willemsen, A., Arends, B., Kotzerke, J.o., ,rg, Bockisch, A., Beyer, T., Chiti, A., and Krause, B.J.
- Abstract
Item does not contain fulltext, The purpose of these guidelines is to assist physicians in recommending, performing, interpreting and reporting the results of FDG PET/CT for oncological imaging of adult patients. PET is a quantitative imaging technique and therefore requires a common quality control (QC)/quality assurance (QA) procedure to maintain the accuracy and precision of quantitation. Repeatability and reproducibility are two essential requirements for any quantitative measurement and/or imaging biomarker. Repeatability relates to the uncertainty in obtaining the same result in the same patient when he or she is examined more than once on the same system. However, imaging biomarkers should also have adequate reproducibility, i.e. the ability to yield the same result in the same patient when that patient would have been examined on different systems and at different imaging sites. Adequate repeatability and reproducibility are essential for the clinical management of patients and the use of FDG PET/CT within multicentre trials. A common standardized imaging procedure will help promote the appropriate use of FDG PET/CT imaging and increase the value of publications and, therefore, their contribution to evidence-based medicine. Moreover, consistency in numerical values between platforms and institutes that acquire the data will potentially enhance the role of semiquantitative and quantitative image interpretation. Precision and accuracy are additionally important as FDG PET/CT is used to evaluate tumour response as well as for diagnosis, prognosis and staging. Therefore both the previous and these new guidelines specifically aim to achieve standardized uptake value harmonization in multicentre settings.
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- 2015
9. SEOM-SERAM-SEMNIM guidelines on the use of functional and molecular imaging techniques in advanced non-small-cell lung cancer
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G. Fernández-Pérez, A. M. García-Vicente, J. Ceballos-Viro, M. P. Fierro-Alanis, A. Luna-Alcalá, J. C. Vilanova-Busquets, R. García-Figueiras, P. Sánchez-Rovira, José E. Alés-Martínez, R. Sánchez-Escribano, R. C. Delgado-Bolton, [Fernandez-Perez, G.] Hosp Univ Rio Hortega, Dept Radiol, Valladolid, Spain, [Sanchez-Escribano, R.] Hosp Univ Burgos, Dept Med Oncol, Burgos, Spain, [Garcia-Vicente, A. M.] Univ Gen Hosp, Dept Nucl Med, Ciudad Real, Spain, [Luna-Alcala, A.] Hlth Time, Clin Nieves, Jaen, Spain, [Luna-Alcala, A.] Case Western Reserve Univ, Dept Radiol, Univ Hosp Cleveland, Cleveland, OH 44106 USA, [Ceballos-Viro, J.] Hosp Nuestra Senora Sonsoles, Oncol Unit, Oncol Med, Complejo Asistencial Avila, Avila 05004, Spain, [Ales-Martinez, J. E.] Hosp Nuestra Senora Sonsoles, Oncol Unit, Oncol Med, Complejo Asistencial Avila, Avila 05004, Spain, [Delgado-Bolton, R. C.] Univ La Rioja, San Pedro Hosp, Dept Diagnost Imaging Radiol & Nucl Med, Logrono, Spain, [Delgado-Bolton, R. C.] Univ La Rioja, San Pedro Hosp, Ctr Biomed Res La Rioja CIBIR, Logrono, Spain, [Vilanova-Busquets, J. C.] Inst Catalan Salud IDI Girona, Serv Radiol, Clin Girona, Girona, Spain, [Sanchez-Rovira, P.] Hosp Univ Jaen, Dept Med Oncol, Jaen, Spain, [Fierro-Alanis, M. P.] Complexo Hosp Univ Santiago de Compostela, Dept Nucl Med, Santiago De Compostela, Spain, and [Garcia-Figueiras, R.] Complexo Hosp Univ Santiago de Compostela, Dept Radiol, Santiago De Compostela, Spain
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Cancer Research ,medicine.medical_specialty ,Diagnostic methods ,Lung Neoplasms ,Multi-detector computed tomography ,Positron-emission-tomography ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Special Article ,0302 clinical medicine ,Targeted therapies ,Magnetic resonance imaging ,Response criteria ,Carcinoma, Non-Small-Cell Lung ,18F-fluorodeoxyglucose positron emission tomography ,Medicine ,Humans ,Bronchogenic-carcinoma ,Lung cancer ,Pseudoprogression ,Neoplasm Staging ,medicine.diagnostic_test ,business.industry ,Diffusion-weighted mri ,General Medicine ,medicine.disease ,Mediastinal invasion ,Fdg-pet/ct ,Molecular Imaging ,Functional imaging ,Oncology ,Computed-tomography ,Positron emission tomography ,Whole-body mr ,Radiation-therapy ,030220 oncology & carcinogenesis ,Practice Guidelines as Topic ,Non small cell ,Radiology ,Molecular imaging ,Neoplasm Recurrence, Local ,business ,Non-small-cell lung cancer - Abstract
Imaging in oncology is an essential tool for patient management but its potential is being profoundly underutilized. Each of the techniques used in the diagnostic process also conveys functional information that can be relevant in treatment decision making. New imaging algorithms and techniques enhance our knowledge about the phenotype of the tumor and its potential response to different therapies. Functional imaging can be defined as the one that provides information beyond the purely morphological data, and include all the techniques that make it possible to measure specific physiological functions of the tumor, whereas molecular imaging would include techniques that allow us to measure metabolic changes. Functional and molecular techniques included in this document are based on multi-detector computed tomography (CT), 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET), magnetic resonance imaging (MRI), and hybrid equipments, integrating PET with CT (PET/CT) or MRI (PET-MRI). Lung cancer is one of the most frequent and deadly tumors although survival is increasing thanks to advances in diagnostic methods and new treatments. This increased survival poises challenges in terms of proper follow-up and definitions of response and progression, as exemplified by immune therapy-related pseudoprogression. In this consensus document, the use of functional and molecular imaging techniques will be addressed to exploit their current potential and explore future applications in the diagnosis, evaluation of response and detection of recurrence of advanced NSCLC.
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- 2017
10. Medical imaging in times of pandemic: focus on the cornerstones of successful imaging
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Roberto C. Delgado Bolton, Francesco Giammarile, Paola Anna Erba, Adriana K. Calapaquí Terán, Delgado Bolton, R, Calapaqui Teran, A, Erba, P, and Giammarile, F
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Diagnostic Imaging ,medicine.medical_specialty ,2019-20 coronavirus outbreak ,COVID-19, medical imaging ,COVID-19 Vaccines ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Messenger ,Lymphadenopathy ,Axillary lymph nodes ,BNT162 Vaccine ,Fluorodeoxyglucose F18 ,Humans ,Incidence ,Pandemics ,Positron Emission Tomography Computed Tomography ,RNA, Messenger ,SARS-CoV-2 ,COVID-19 ,Pandemic ,Medical imaging ,medicine ,Radiology, Nuclear Medicine and imaging ,Medical physics ,Positron Emission Tomography-Computed Tomography ,business.industry ,Vaccination ,General Medicine ,False-positive [18F]FDG uptake ,Oncologic imaging ,Editorial ,RNA ,Original Article ,business - Abstract
Purpose Nationwide mass vaccination against Covid-19 started in Israel in late 2020. Soon we identified on [18F]FDG PET-CT studies vaccine-associated hypermetabolic lymphadenopathy (VAHL) in axillary or supraclavicular lymph nodes (ASLN) ipsilateral to the vaccination site. Sometimes, differentiation between the malignant and benign nature of the hypermetabolic lymphadenopathy (HLN) could not be made, and equivocal HLN (EqHL) was reported. The purpose of the study was to determine the overall incidence of VAHL after BNT162b2 vaccination and also its relevance to PET-CT interpretation in oncologic patients. Methods A total of 951 consecutive patients that underwent [18F]FDG PET-CT studies in our department were interviewed regarding the sites and dates of the vaccine doses. A total of 728 vaccinated patients (All-Vac group) were included: 346 received the first dose only (Vac-1 group) and 382 received the booster dose as well (Vac-2 group). Studies were categorized as no HLN, malignant-HLN (MHL), VAHL, or EqHL. In studies with VAHL, location, [18F]FDG-intensity uptake and nodes size were recorded. Results The incidences of HLN were 45.6%, 36.4%, and 53.9% in All-Vac, Vac-1, and Vac-2 groups, respectively. VAHL was reported in 80.1% of vaccinated patients with HLN. Lower incidences of VAHL were found during the first 5 days or in the third week after the first vaccine and beyond 20 days after the booster dose. In 49 of 332 (14.8%) vaccinated patients, we could not determine whether HLN was MHL or VAHL. Breast cancer and lymphoma were the leading diseases with EqHL. Conclusion VAHL is frequently observed after BNT162b2 administration, more commonly and with higher intensity following the booster dose. To minimize false and equivocal reports in oncological patients, timing of [18F]FDG PET-CT should be based on the time intervals found to have a lower incidence of VAHL, and choice of vaccine injection site should be advised, mainly in patients where ASLN are a relevant site of tumor involvement.
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- 2021
11. ECCO Essential Requirements for Quality Cancer Care: Prostate cancer
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Peter Hoskin, Alberto Costa, Michael Höckel, Helen Boyle, Philip Poortmans, Rui Medeiros, Maurizio Colecchia, Tiina Saarto, Ken Mastris, Roberto Delgado-Bolton, Kay Leonard, Maurizio Brausi, Raymond Oyen, Marc Beishon, Peter Selby, Ian Banks, Peter Naredi, Theo M. de Reijke, Riccardo Valdagni, József Lövey, Pablo Maroto, Elisabeth Andritsch, Brausi, M., Hoskin, P., Andritsch, E., Banks, I., Beishon, M., Boyle, H., Colecchia, M, Delgado-Bolton, R., Höckel, M., Leonard, K., Lövey, J., Maroto, P., Mastris, K., Medeiros, R., Naredi, P., Oyen, R., de Reijke, T., Selby, P., Saarto, T., Valdagni, R., Costa, A., and Poortmans, P.
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Male ,0301 basic medicine ,Palliative care ,media_common.quotation_subject ,Medical Oncology ,03 medical and health sciences ,Prostate cancer ,0302 clinical medicine ,Nursing ,Multidisciplinary approach ,Survivorship curve ,Health care ,medicine ,Humans ,Quality (business) ,Pathways ,Socioeconomic status ,Centres ,Quality of Health Care ,media_common ,Patient Care Team ,Multidisciplinary ,business.industry ,Prostatic Neoplasms ,Cancer ,Units ,Hematology ,medicine.disease ,Quality ,3. Good health ,Europe ,030104 developmental biology ,Oncology ,030220 oncology & carcinogenesis ,business ,Delivery of Health Care - Abstract
Background ECCO Essential Requirements for Quality Cancer Care (ERQCC) are written by experts representing all disciplines involved in cancer care in Europe. They give oncology teams, patients, policymakers and managers an overview of essential care throughout the patient journey. Prostate cancer Prostate cancer is the second most common male cancer and has a wide variation in outcomes in Europe. It has complex diagnosis and treatment challenges, and is a major healthcare burden. Care must only be a carried out in prostate/urology cancer units or centres that have a core multidisciplinary team (MDT) and an extended team of health professionals. Such units are far from universal in European countries. To meet European aspirations for comprehensive cancer control, healthcare organisations must consider the requirements in this paper, paying particular attention to multidisciplinarity and patient-centred pathways from diagnosis, to treatment, to survivorship.
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- 2020
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12. The '3M' Approach to Cardiovascular Infections
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Margarita Kirienko, Elena Lazzeri, Riemer H. J. A. Slart, Paola Anna Erba, Roberto C. Delgado Bolton, Martina Sollini, Roberto Boni, Raffaella Nice Berchiolli, Alexia Rossi, Sollini, M, Berchiolli, R, Delgado Bolton, R, Rossi, A, Kirienko, M, Boni, R, Lazzeri, E, Slart, R, and Erba, P
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medicine.medical_specialty ,Cardiovascular infection ,Cardiovascular Infections ,Interdisciplinary Research ,MEDLINE ,RADIOLABELED LEUKOCYTE SCINTIGRAPHY ,Early detection ,030204 cardiovascular system & hematology ,Cardiovascular Infection ,Imaging data ,Multimodal Imaging ,030218 nuclear medicine & medical imaging ,Multimodality ,03 medical and health sciences ,High morbidity ,0302 clinical medicine ,VENTRICULAR-ASSIST DEVICES ,Multidisciplinary approach ,AMERICAN-HEART-ASSOCIATION ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Radioactive Tracers ,Intensive care medicine ,business.industry ,EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY ,LOW-CARBOHYDRATE-DIET ,STAPHYLOCOCCUS-AUREUS BACTEREMIA ,DEVICE-RELATED INFECTIONS ,Patient management ,PROSTHETIC GRAFT INFECTION ,AORTIC ENDOGRAFT INFECTION ,IMPLANTABLE ELECTRONIC DEVICES ,business ,Human - Abstract
Cardiovascular infections are associated with high morbidity and mortality. Early diagnosis is crucial for adequate patient management, as early treatment improves the prognosis. The diagnosis cannot be made on the basis of a single symptom, sign, or diagnostic test. Rather, the diagnosis requires a multidisciplinary discussion in addition to the integration of clinical signs, microbiology data, and imaging data. The application of multimodality imaging, including molecular imaging techniques, has improved the sensitivity to detect infections involving heart valves and vessels and implanted cardiovascular devices while also allowing for early detection of septic emboli and metastatic infections before these become clinically apparent. In this review, we describe data supporting the use of a Multimodality, Multitracer, and Multidisciplinary approach (the 3M approach) to cardiovascular infections. In particular, the role of white blood cell SPECT/CT and [F-18]FDG PET/CT in most prevalent and clinically relevant cardiovascular infections will be discussed. In addition, the needs of advanced hybrid equipment, dedicated imaging acquisition protocols, specific expertise for image reading, and interpretation in this field are discussed, emphasizing the need for a specific reference framework within a Cardiovascular Multidisciplinary Team Approach to select the best test or combination of tests for each specific clinical situation. (C) 2018 Elsevier Inc. All rights reserved.
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- 2018
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13. ECCO essential requirements for quality cancer care: Oesophageal and gastric cancer
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Simon Oberst, Alberto Costa, Radka Obermannova, Marc Beishon, Venetia Wynter-Blyth, Irena Stenglova Netikova, Ahmed Ba-Ssalamah, Jan Willem Dekker, Thomas Seufferlein, József Lövey, Karin Haustermans, Elisabeth Andritsch, William H. Allum, Fátima Carneiro, Roberto Delgado-Bolton, Geoffrey Henning, Bettina Hutter, Peter Naredi, Florian Lordick, Tiina Saarto, Fernando Cassinello, Sapna Sheth, Maria Alsina, Marco Braga, Siri Rostoft, Carmela Caballero, Allum, W, Lordick, F, Alsina, M, Andritsch, E, Ba-Ssalamah, A, Beishon, M, Braga, M, Caballero, C, Carneiro, F, Cassinello, F, Dekker, J, Delgado-Bolton, R, Haustermans, K, Henning, G, Hutter, B, Lovey, J, Netikova, I, Obermannova, R, Oberst, S, Rostoft, S, Saarto, T, Seufferlein, T, Sheth, S, Wynter-Blyth, V, Costa, A, and Naredi, P
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Healthcare system ,Palliative care ,Esophageal Neoplasms ,Stomach cancer ,Essential requirement ,media_common.quotation_subject ,Audit ,Guideline ,Medical Oncology ,03 medical and health sciences ,0302 clinical medicine ,Nursing ,Stomach Neoplasms ,Multidisciplinary approach ,Patient-centred ,Health care ,Humans ,Medicine ,Quality (business) ,Quality of Health Care ,media_common ,Service (business) ,Care pathway ,Multidisciplinary ,Cancer unit ,business.industry ,Oesophageal cancer ,Audit, cancer centre, Cancer unit, Care pathways, Essential requirements, Europe, Gastric cancer, Multidisciplinary team, Oesophageal cancer, Oesophageal-gastric cancer, Organisation of care, Patient information, Patient-centred, Quality, Quality assurance, Stomach cancer ,Cancer ,Multidisciplinary team ,Hematology ,Oesophageal-gastric cancer ,medicine.disease ,Quality ,Organisation of care ,Quality assurance ,3. Good health ,Europe ,Patient information ,Oncology ,Health inequalitie ,030220 oncology & carcinogenesis ,Cancer centre ,030211 gastroenterology & hepatology ,Gastric cancer ,business ,Delivery of Health Care - Abstract
Background ECCO essential requirements for quality cancer care (ERQCC) are checklists and explanations of organisation and actions that are necessary to give high-quality care to patients who have a specific type of cancer. They are written by European experts representing all disciplines involved in cancer care. ERQCC papers give oncology teams, patients, policymakers and managers an overview of the elements needed in any healthcare system to provide high quality of care throughout the patient journey. References are made to clinical guidelines and other resources where appropriate, and the focus is on care in Europe. Oesophageal and gastric: essential requirements for quality care • Oesophageal and gastric (OG) cancers are a challenging tumour group with a poor prognosis and wide variation in outcomes among European countries. Increasing numbers of older people are contracting the diseases, and treatments and care pathways are becoming more complex in both curative and palliative settings. • High-quality care can only be a carried out in specialised OG cancer units or centres which have both a core multidisciplinary team and an extended team of allied professionals, and which are subject to quality and audit procedures. Such units or centres are far from universal in all European countries. • It is essential that, to meet European aspirations for comprehensive cancer control, healthcare organisations implement the essential requirements in this paper, paying particular attention to multidisciplinarity and patient-centred pathways from diagnosis, to treatment, to survivorship. Conclusion Taken together, the information presented in this paper provides a comprehensive description of the essential requirements for establishing a high-quality OG cancer service. The ERQCC expert group is aware that it is not possible to propose a ‘one size fits all’ system for all countries, but urges that access to multidisciplinary units or centres must be guaranteed for all those with OG cancer.
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- 2018
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14. Unusual Uptake of [ 131 I] in a Tenosynovial Giant Cell Tumour Relapse in a Patient with Differentiated Thyroid Cancer.
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Cañete Sánchez FM, Romero Robles LG, Boulvard Chollet XL, Mangas Losada M, Garrastachu P, Cabrera Villegas A, Ramírez Lasanta R, and Delgado Bolton R
- Abstract
A 77-year-old woman with follicular thyroid cancer underwent total thyroidectomy and subsequent Iodine-131 remnant ablation. She had a history of a wide tenosynovial giant cell tumor (TGCT) of the right wrist and hand that had been resected thirteen years ago. Post-therapeutic scintigraphy and single photon emission computed tomography showed mild uptake on the distal right forearm, wrist and hand. Magnetic resonance imaging and posterior histopathology confirmed a relapse of TGCT. No radioiodine adverse effects were reported after a one-year follow-up. As far as we know, this report is the first in the literature to a TGCT visualized on post-therapy radioiodine scan., Competing Interests: Conflict of Interest: No conflict of interest was declared by the authors., (©Copyright 2022 by Turkish Society of Nuclear Medicine, Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi.)
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- 2022
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15. ECCO Essential Requirements for Quality Cancer Care: Prostate cancer.
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Brausi M, Hoskin P, Andritsch E, Banks I, Beishon M, Boyle H, Colecchia M, Delgado-Bolton R, Höckel M, Leonard K, Lövey J, Maroto P, Mastris K, Medeiros R, Naredi P, Oyen R, de Reijke T, Selby P, Saarto T, Valdagni R, Costa A, and Poortmans P
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- Europe, Humans, Male, Medical Oncology, Patient Care Team, Delivery of Health Care, Prostatic Neoplasms, Quality of Health Care
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Background: ECCO Essential Requirements for Quality Cancer Care (ERQCC) are written by experts representing all disciplines involved in cancer care in Europe. They give oncology teams, patients, policymakers and managers an overview of essential care throughout the patient journey., Prostate Cancer: Prostate cancer is the second most common male cancer and has a wide variation in outcomes in Europe. It has complex diagnosis and treatment challenges, and is a major healthcare burden. Care must only be a carried out in prostate/urology cancer units or centres that have a core multidisciplinary team (MDT) and an extended team of health professionals. Such units are far from universal in European countries. To meet European aspirations for comprehensive cancer control, healthcare organisations must consider the requirements in this paper, paying particular attention to multidisciplinarity and patient-centred pathways from diagnosis, to treatment, to survivorship., Competing Interests: Declaration of Competing Interest The authors declare no conflicts of interest for this paper., (Copyright © 2020 Elsevier B.V. All rights reserved.)
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- 2020
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16. Improvement of Inter-Professional Collaborative Work Abilities in Mexican Medical and Nursing Students: A Longitudinal Study.
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Tuirán-Gutiérrez GJ, San-Martín M, Delgado-Bolton R, Bartolomé B, and Vivanco L
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Background: Inter-professional and interpersonal relationships in collaborative work environments can prove to be critical elements in healthcare practice. When implementers fail to understand the importance of a collaborative perspective, this can lead to communication problems which ultimately harm the users. Objectives: To improve the inter-professional collaborative work skills of Mexican students in their first year of medical and nursing degrees through the use of a training program geared toward development of interpersonal skills and interdisciplinary work. Methods: The sample was composed of 162 students (62 males and 99 females) from the School of Healthcare Sciences of the Autonomous University of Coahuila, Mexico. The main measures used were the Jefferson Scale of Empathy (JSE); the Jefferson Scale of Attitudes toward Inter-Professional Collaborative Work between Medical and Nursing Professionals (JSAPNC); and the Jefferson Scale of Lifelong Learning (JeffSPLL). The entire sample was divided into two groups (experimental and control groups). Both groups attended an extra-curricular program using a coaching methodology. In the first case the topic focused on attitudes toward inter-professional collaborative work. In the second case, the program focused on addiction. Both programs ran for 4 months. Psychometric instruments were applied at the beginning and at the end of both programs. After analyzing the reliability of the instruments, an ANOVA test was performed. Results: The control group of medical students showed a deterioration in the development of collaborative work skills ( p < 0.01), whereas in the experimental group this deterioration was not present. In the experimental group of nursing students, a significant increase in the development of collaborative work skills ( p < 0.05) was observed. The differences were clearly due to the professional area of study ( p < 0.001). Conclusion: There are differences in collaborative work skill development among different professional areas. These differences can be reduced through the implementation of a program aimed at developing collaborative work and interpersonal skills in the early stages of training.
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- 2019
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17. Usefulness of 18 F Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Infective Endocarditis in Daily Practice: Individualized Analysis of Each Potential Focus of Infection: A Prospective Cohort Study.
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Sánchez-Enrique C, Olmos C, Jiménez-Ballvé A, Fernández-Pérez C, Ferrera C, Pérez-Castejón MJ, Ortega Candil A, Delgado-Bolton R, Carnero M, Maroto L, Carreras JL, and Vilacosta I
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- Defibrillators, Implantable adverse effects, Endocarditis etiology, Endocarditis mortality, Endocarditis surgery, Heart Valve Prosthesis adverse effects, Heart Valve Prosthesis Implantation adverse effects, Heart Valve Prosthesis Implantation instrumentation, Heart Valves surgery, Humans, Observer Variation, Pacemaker, Artificial adverse effects, Predictive Value of Tests, Prognosis, Prospective Studies, Prosthesis-Related Infections etiology, Prosthesis-Related Infections mortality, Prosthesis-Related Infections surgery, Reproducibility of Results, Risk Factors, Endocarditis diagnostic imaging, Fluorodeoxyglucose F18 administration & dosage, Heart Valves diagnostic imaging, Positron Emission Tomography Computed Tomography, Prosthesis-Related Infections diagnostic imaging, Radiopharmaceuticals administration & dosage
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- 2018
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18. Reply: Staging, Restaging, and Treatment Response Assessment in Lymphomas: What We Should Know.
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Delgado-Bolton R, Esposito G, Colletti PM, and Jadvar H
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- Fluorodeoxyglucose F18, Humans, Lymphoma
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- 2018
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19. ECCO essential requirements for quality cancer care: Oesophageal and gastric cancer.
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Allum W, Lordick F, Alsina M, Andritsch E, Ba-Ssalamah A, Beishon M, Braga M, Caballero C, Carneiro F, Cassinello F, Dekker JW, Delgado-Bolton R, Haustermans K, Henning G, Hutter B, Lövey J, Netíková IŠ, Obermannová R, Oberst S, Rostoft S, Saarto T, Seufferlein T, Sheth S, Wynter-Blyth V, Costa A, and Naredi P
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- Delivery of Health Care methods, Delivery of Health Care organization & administration, Europe, Humans, Medical Oncology methods, Medical Oncology organization & administration, Quality of Health Care, Delivery of Health Care standards, Esophageal Neoplasms therapy, Medical Oncology standards, Stomach Neoplasms therapy
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Background: ECCO essential requirements for quality cancer care (ERQCC) are checklists and explanations of organisation and actions that are necessary to give high-quality care to patients who have a specific type of cancer. They are written by European experts representing all disciplines involved in cancer care. ERQCC papers give oncology teams, patients, policymakers and managers an overview of the elements needed in any healthcare system to provide high quality of care throughout the patient journey. References are made to clinical guidelines and other resources where appropriate, and the focus is on care in Europe., Oesophageal and Gastric: ESSENTIAL REQUIREMENTS FOR QUALITY CARE: CONCLUSION: Taken together, the information presented in this paper provides a comprehensive description of the essential requirements for establishing a high-quality OG cancer service. The ERQCC expert group is aware that it is not possible to propose a 'one size fits all' system for all countries, but urges that access to multidisciplinary units or centres must be guaranteed for all those with OG cancer., (Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.)
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- 2018
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20. ECCO essential requirements for quality cancer care: Melanoma.
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Wouters MW, Michielin O, Bastiaannet E, Beishon M, Catalano O, Del Marmol V, Delgado-Bolton R, Dendale R, Trill MD, Ferrari A, Forsea AM, Kreckel H, Lövey J, Luyten G, Massi D, Mohr P, Oberst S, Pereira P, Prata JPP, Rutkowski P, Saarto T, Sheth S, Spurrier-Bernard G, Vuoristo MS, Costa A, and Naredi P
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- Delivery of Health Care methods, Delivery of Health Care organization & administration, Europe, Humans, Medical Oncology methods, Medical Oncology organization & administration, Quality of Health Care, Delivery of Health Care standards, Medical Oncology standards, Melanoma therapy
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Background: ECCO essential requirements for quality cancer care (ERQCC) are explanations and descriptions of challenges, organisation and actions that are necessary to give high-quality care to patients who have a specific type of cancer. They are written by European experts representing all disciplines involved in cancer care. ERQCC papers give oncology teams, patients, policymakers and managers an overview of the elements needed in any healthcare system to provide high quality of care throughout the patient journey. References are made to clinical guidelines and other resources where appropriate, and the focus is on care in Europe., Melanoma: ESSENTIAL REQUIREMENTS FOR QUALITY CARE: CONCLUSION: Taken together, the information presented in this paper provides a comprehensive description of the essential requirements for establishing a high-quality service for melanoma. The ERQCC expert group is aware that it is not possible to propose a 'one size fits all' system for all countries, but urges that access to multidisciplinary teams and specialised treatments is guaranteed to all patients with melanoma., (Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.)
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- 2018
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21. Appropriate Use Criteria for 18 F-FDG PET/CT in Restaging and Treatment Response Assessment of Malignant Disease.
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Jadvar H, Colletti PM, Delgado-Bolton R, Esposito G, Krause BJ, Iagaru AH, Nadel H, Quinn DI, Rohren E, Subramaniam RM, Zukotynski K, Kauffman J, Ahuja S, and Griffeth L
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- Humans, Neoplasm Staging, Neoplasms therapy, Treatment Outcome, Fluorodeoxyglucose F18, Neoplasms diagnostic imaging, Neoplasms pathology, Positron Emission Tomography Computed Tomography
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- 2017
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22. Role of a Semiotics-Based Curriculum in Empathy Enhancement: A Longitudinal Study in Three Dominican Medical Schools.
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San-Martín M, Delgado-Bolton R, and Vivanco L
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Background: Empathy in the context of patient care is defined as a predominantly cognitive attribute that involves an understanding of the patient's experiences, concerns, and perspectives, combined with a capacity to communicate this understanding and an intention to help. In medical education, it is recognized that empathy can be improved by interventional approaches. In this sense, a semiotic-based curriculum could be an important didactic tool for improving medical empathy. The main purpose of this study was to determine if in medical schools where a semiotic-based curriculum is offered, the empathetic orientation of medical students improves as a consequence of the acquisition and development of students' communication skills that are required in clinician-patient encounters. Design: This quasi-experimental study was conducted in three medical schools of the Dominican Republic that offer three different medical curricula: (i) a theoretical and practical semiotic-based curriculum; (ii) a theoretical semiotic-based curriculum; and (iii) a curriculum without semiotic courses. The Jefferson scale of empathy was administered in two different moments to students enrolled in pre-clinical cycles of those institutions. Data was subjected to comparative statistical analysis and logistic regression analysis. Results: The study included 165 students (55 male and 110 female). Comparison analysis showed statistically significant differences in the development of empathy among groups ( p < 0.001). Logistic regression confirmed that gender, age, and a semiotic-based curriculum contributed toward the enhancement of empathy. Conclusion: These findings demonstrate the importance of medical semiotics as a didactic teaching method for improving beginners' empathetic orientation in patients' care.
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- 2017
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23. Human Connections and Their Roles in the Occupational Well-being of Healthcare Professionals: A Study on Loneliness and Empathy.
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Soler-Gonzalez J, San-Martín M, Delgado-Bolton R, and Vivanco L
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Human connections are key to the promotion of health and prevention of illness; moreover, illness can cause deterioration of human connections. Healthcare professional-patient relationships are key to ensuring the preservation of adequate human connections. It is important for healthcare professionals to develop their ability to foster satisfactory human connections because: (i) they represent social support for patients; and (ii) they prevent work-related stress. In this study we assessed the relationship between absence (loneliness) and presence (empathy) of human connections with the occupational well-being of healthcare professionals. The Scale of Collateral Effects, which measures somatization, exhaustion, and work alienation; the Jefferson Scale of Empathy; and the Social and Emotional Loneliness Scale for Adults, were mailed to 628 healthcare professionals working in Spanish public healthcare institutions. The following explanatory variables were used to evaluate work well-being: (a) empathy, as a professional competence; (b) loneliness, age, and family burden, as psychological indicators; and (c) professional experience, work dedication, and salary, as work indicators. Comparison, correlation, and regression analyses were performed to measure the relationships among these variables and occupational well-being. Of 628 surveys mailed, 433 (69% response rate) were returned fully completed. Adequate reliability was confirmed for all instruments. The entire sample was divided into four groups, based on the combined variable, "occupation by sex." Comparative analyses demonstrated differences among "occupation by sex" groups in collateral effects ( p = 0.03) and empathy ( p = 0.04), but not loneliness ( p = 0.84). Inverse associations between empathy and collateral effects were confirmed for somatization ( r = -0.16; p < 0.001), exhaustion ( r = -0.14; p = 0.003), and work alienation ( r = -0.16; p < 0.001). Furthermore, loneliness was positively associated with collateral effects ( r = 0.22; p < 0.001). Neither family burden, nor work dedication to clinics or management activities were associated with the three collateral effects measured. These findings support an important role for empathy in the prevention of work stress in healthcare professionals. They also confirm that loneliness, as a multidimensional and domain specific experience, is detrimental to occupational well-being.
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- 2017
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24. ECCO Essential Requirements for Quality Cancer Care: Colorectal Cancer. A critical review.
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Beets G, Sebag-Montefiore D, Andritsch E, Arnold D, Beishon M, Crul M, Dekker JW, Delgado Bolton R, Fléjou JF, Grisold W, Henning G, Laghi A, Lovey J, Negrouk A, Pereira P, Roca P, Saarto T, Seufferlein T, Taylor C, Ugolini G, Velde CV, Herck BV, Yared W, Costa A, and Naredi P
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- Delivery of Health Care standards, Europe, Humans, Mass Screening, Quality of Health Care, Risk Factors, Colorectal Neoplasms diagnosis, Colorectal Neoplasms prevention & control, Colorectal Neoplasms therapy
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Background: ECCO essential requirements for quality cancer care (ERQCC) are checklists and explanations of organisation and actions that are necessary to give high-quality care to patients who have a specific tumour type. They are written by European experts representing all disciplines involved in cancer care. ERQCC papers give oncology teams, patients, policymakers and managers an overview of the elements needed in any healthcare system to provide high quality of care throughout the patient journey. References are made to clinical guidelines and other resources where appropriate, and the focus is on care in Europe. Colorectal cancer: essential requirements for quality care CONCLUSION: Taken together, the information presented in this paper provides a comprehensive description of the essential requirements for establishing a high-quality CRC service. The ECCO expert group is aware that it is not possible to propose a 'one size fits all' system for all countries, but urges that access to multidisciplinary units or centres must be guaranteed for all those with CRC., (Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.)
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- 2017
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25. ECCO Essential Requirements for Quality Cancer Care: Soft Tissue Sarcoma in Adults and Bone Sarcoma. A critical review.
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Andritsch E, Beishon M, Bielack S, Bonvalot S, Casali P, Crul M, Delgado Bolton R, Donati DM, Douis H, Haas R, Hogendoorn P, Kozhaeva O, Lavender V, Lovey J, Negrouk A, Pereira P, Roca P, de Lempdes GR, Saarto T, van Berck B, Vassal G, Wartenberg M, Yared W, Costa A, and Naredi P
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- Adult, Europe, Humans, Palliative Care, Quality of Life, Survivors, Bone Neoplasms diagnosis, Bone Neoplasms pathology, Bone Neoplasms therapy, Osteosarcoma diagnosis, Osteosarcoma pathology, Osteosarcoma therapy, Sarcoma diagnosis, Sarcoma pathology, Sarcoma therapy
- Abstract
Background: ECCO essential requirements for quality cancer care (ERQCC) are checklists and explanations of organisation and actions that are necessary to give high-quality care to patients who have a specific tumour type. They are written by European experts representing all disciplines involved in cancer care. ERQCC papers give oncology teams, patients, policymakers and managers an overview of the elements needed in any healthcare system to provide high quality of care throughout the patient journey. References are made to clinical guidelines and other resources where appropriate, and the focus is on care in Europe. Sarcoma: essential requirements for quality care • Sarcomas - which can be classified into soft tissue and bone sarcomas - are rare, but all rare cancers make up more than 20% of cancers in Europe, and there are substantial inequalities in access to high-quality care. Sarcomas, of which there are many subtypes, comprise a particularly complex and demanding challenge for healthcare systems and providers. This paper presents essential requirements for quality cancer care of soft tissue sarcomas in adults and bone sarcomas. • High-quality care must only be carried out in specialised sarcoma centres (including paediatric cancer centres) which have both a core multidisciplinary team and an extended team of allied professionals, and which are subject to quality and audit procedures. Access to such units is far from universal in all European countries. • It is essential that, to meet European aspirations for high-quality comprehensive cancer control, healthcare organisations implement the requirements in this paper, paying particular attention to multidisciplinarity and patient-centred pathways from diagnosis and follow-up, to treatment, to improve survival and quality of life for patients., Conclusion: Taken together, the information presented in this paper provides a comprehensive description of the essential requirements for establishing a high-quality service for soft tissue sarcomas in adults and bone sarcomas. The ECCO expert group is aware that it is not possible to propose a 'one size fits all' system for all countries, but urges that access to multidisciplinary teams is guaranteed to all patients with sarcoma., (Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.)
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- 2017
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26. Professionalism and Occupational Well-Being: Similarities and Differences Among Latin American Health Professionals.
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San-Martín M, Delgado-Bolton R, and Vivanco L
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Context: Empathy, teamwork, and lifelong learning are described as key elements of professionalism. The first recipients of their benefits are professionals themselves. Paradoxically, scarce studies have reported association between professionalism and occupational well-being. The main purpose of this study was to characterize the influence that empathy, teamwork, and lifelong learning, play in the occupational well-being of physicians and nurses working in Latin American healthcare institutions. Materials and Methods: The Jefferson Scale of Empathy, the Jefferson Scale of Attitudes toward Physician-Nurse Collaboration, the Jefferson Scale of Physicians Lifelong Learning, and the Scale of Collateral Effects (somatization, exhaustion, and work alienation), were administered to 522 physicians and nurses working in institutions of Mexico, Colombia, Ecuador, and Argentina. Internal reliability was calculated. Gender and discipline were used as explanatory variables in comparison analysis. Two-way analysis of variance was performed to examine differences due to the main effects of the gender, and discipline, and to determine possible combined effects. Correlation analysis was performed to measure associations between collateral effects and age, and between collateral effects and professionalism. Results: A total of 353 (68%) surveys were returned fully completed. Adequate reliability was confirmed in all instruments. No differences were found among countries for collateral effects. Correlation analysis confirmed in physicians an inverse association between empathy and collateral effects ( P = -0.16; p < 0.05), and between collateral effects and lifelong learning ( P = -0.18; p < 0.01). In nurses, this association was confirmed only for empathy ( P = -0.19; p < 0.05). Important differences in the development of professionalism and in its effects on occupational well-being appeared associated to inter-professional collaboration and work roles. An inverse correlation between age and collateral effects was confirmed in physicians ( P = -0.22; p < 0.001) and in nurses ( P = -28; p < 0.001). Comparison by gender confirmed higher somatization in women physicians and nurses than in men groups ( p < 0.001). On the other hand, comparison by discipline confirmed higher exhaustion and alienation in physicians than in nurses ( p < 0.01). Conclusion: The findings support the importance that empathy, teamwork, and lifelong learning have in practitioners' health and welfare, and the role that cultural behaviors, associated to work professional models and social stereotypes, play in the interaction between professionalism and occupational well-being.
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- 2017
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27. [Medical empathy of physicians-in-training who are enrolled in professional training programs. A comparative intercultural study in Spain].
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Delgado-Bolton R, San-Martín M, Alcorta-Garza A, and Vivanco L
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- Cross-Sectional Studies, Cultural Characteristics, Education, Medical, Humans, Psychometrics, Spain, Surveys and Questionnaires, Empathy, Physicians
- Abstract
Objective: To characterise some of the environmental factors that are sensitive to cultural influence, and are involved in the development of medical empathy in Spanish and Latin American physicians-in-training., Design: Cross-sectional study using questionnaires., Setting: Primary care and specialized medicine centres of the Healthcare System of La Rioja, Logroño, Spain., Participants: Physicians-in-training MAIN MEASUREMENTS: : Empathy was measured using the Jefferson Scale of Physician Empathy, version for healthcare professionals (JSE-HP). Socio-demographic, academic, and professional background information was collected., Results: A total of 104 residents (67 from Spain and 32 from Latin America) answered and returned the questionnairess. The JSE-HP showed adequate psychometric properties. The empathy mean score of Spanish group was higher than that of the Latin American group (P=.01). Differences in the development of empathy were associated with: the development of professional models (P<.001), the positive encounter with other professionals (P=.001), and with a continuing medical education (P=.008)., Conclusions: Some factors involved in the development of empathy that are sensitive to cultural influence have been characterised. The development of future research areas is suggested., (Copyright © 2015 Elsevier España, S.L.U. All rights reserved.)
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- 2016
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28. Cross-Validation of the Spanish HP-Version of the Jefferson Scale of Empathy Confirmed with Some Cross-Cultural Differences.
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Alcorta-Garza A, San-Martín M, Delgado-Bolton R, Soler-González J, Roig H, and Vivanco L
- Abstract
Context: Medical educators agree that empathy is essential for physicians' professionalism. The Health Professional Version of the Jefferson Scale of Empathy (JSE-HP) was developed in response to a need for a psychometrically sound instrument to measure empathy in the context of patient care. Although extensive support for its validity and reliability is available, the authors recognize the necessity to examine psychometrics of the JSE-HP in different socio-cultural contexts to assure the psychometric soundness of this instrument. The first aim of this study was to confirm its psychometric properties in the cross-cultural context of Spain and Latin American countries. The second aim was to measure the influence of social and cultural factors on the development of medical empathy in health practitioners., Methods: The original English version of the JSE-HP was translated into International Spanish using back-translation procedures. The Spanish version of the JSE-HP was administered to 896 physicians from Spain and 13 Latin American countries. Data were subjected to exploratory factor analysis using principal component analysis (PCA) with oblique rotation (promax) to allow for correlation among the resulting factors, followed by a second analysis, using confirmatory factor analysis (CFA). Two theoretical models, one based on the English JSE-HP and another on the first Spanish student version of the JSE (JSE-S), were tested. Demographic variables were compared using group comparisons., Results: A total of 715 (80%) surveys were returned fully completed. Cronbach's alpha coefficient of the JSE for the entire sample was 0.84. The psychometric properties of the Spanish JSE-HP matched those of the original English JSE-HP. However, the Spanish JSE-S model proved more appropriate than the original English model for the sample in this study. Group comparisons among physicians classified by gender, medical specialties, cultural and cross-cultural backgrounds yielded statistically significant differences (p < 0.001)., Conclusions: The findings support the underlying factor structure of the Jefferson Scale of Empathy (JSE). The results reveal the importance of culture in the development of medical empathy. The cross-cultural differences described could open gates for further lines of medical education research.
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- 2016
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29. Selected CD133⁺ progenitor cells to promote angiogenesis in patients with refractory angina: final results of the PROGENITOR randomized trial.
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Jimenez-Quevedo P, Gonzalez-Ferrer JJ, Sabate M, Garcia-Moll X, Delgado-Bolton R, Llorente L, Bernardo E, Ortega-Pozzi A, Hernandez-Antolin R, Alfonso F, Gonzalo N, Escaned J, Bañuelos C, Regueiro A, Marin P, Fernandez-Ortiz A, Neves BD, Del Trigo M, Fernandez C, Tejerina T, Redondo S, Garcia E, and Macaya C
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- AC133 Antigen, Aged, Angina Pectoris diagnostic imaging, Antigens, CD genetics, Double-Blind Method, Endothelial Progenitor Cells cytology, Endothelial Progenitor Cells metabolism, Female, Glycoproteins genetics, Humans, Male, Middle Aged, Peptides genetics, Prospective Studies, Stem Cell Transplantation adverse effects, Tomography, Emission-Computed, Single-Photon, Angina Pectoris therapy, Antigens, CD metabolism, Endothelial Progenitor Cells transplantation, Glycoproteins metabolism, Neovascularization, Physiologic, Peptides metabolism, Stem Cell Transplantation methods
- Abstract
Rationale: Refractory angina constitutes a clinical problem., Objective: The aim of this study was to assess the safety and the feasibility of transendocardial injection of CD133(+) cells to foster angiogenesis in patients with refractory angina., Methods and Results: In this randomized, double-blinded, multicenter controlled trial, eligible patients were treated with granulocyte colony-stimulating factor, underwent an apheresis and electromechanical mapping, and were randomized to receive treatment with CD133(+) cells or no treatment. The primary end point was the safety of transendocardial injection of CD133(+) cells, as measured by the occurrence of major adverse cardiac and cerebrovascular event at 6 months. Secondary end points analyzed the efficacy. Twenty-eight patients were included (n=19 treatment; n=9 control). At 6 months, 1 patient in each group had ventricular fibrillation and 1 patient in each group died. One patient (treatment group) had a cardiac tamponade during mapping. There were no significant differences between groups with respect to efficacy parameters; however, the comparison within groups showed a significant improvement in the number of angina episodes per month (median absolute difference, -8.5 [95% confidence interval, -15.0 to -4.0]) and in angina functional class in the treatment arm but not in the control group. At 6 months, only 1 simple-photon emission computed tomography (SPECT) parameter: summed score improved significantly in the treatment group at rest and at stress (median absolute difference, -1.0 [95% confidence interval, -1.9 to -0.1]) but not in the control arm., Conclusions: Our findings support feasibility and safety of transendocardial injection of CD133(+) cells in patients with refractory angina. The promising clinical results and favorable data observed in SPECT summed score may set up the basis to test the efficacy of cell therapy in a larger randomized trial., (© 2014 American Heart Association, Inc.)
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- 2014
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30. Infected marantic endocarditis with leukemoid reaction.
- Author
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Sánchez-Enrique C, Vilacosta I, Moreno HG, Delgado-Bolton R, Pérez-Alonso P, Martínez A, Vivas D, Ferrera C, and Olmos C
- Subjects
- Aged, Female, Humans, Echocardiography, Endocarditis diagnostic imaging, Leukemoid Reaction diagnostic imaging, Positron-Emission Tomography, Tomography, X-Ray Computed
- Published
- 2014
- Full Text
- View/download PDF
31. Very late mycotic pseudoaneurysm associated with drug-eluting stent fracture.
- Author
-
Del Trigo M, Jimenez-Quevedo P, Fernandez-Golfin C, Vaño E, Delgado-Bolton R, Alfonso F, Gonzalo N, Kallmeyer A, Montes L, Escribano N, Hernandez-Antolin R, and Macaya C
- Subjects
- Aged, Aneurysm, False diagnostic imaging, Echocardiography, Female, Humans, Treatment Failure, Aneurysm, False etiology, Drug-Eluting Stents adverse effects
- Published
- 2012
- Full Text
- View/download PDF
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