This paper explores the application of structural tessellation in architectural and structural design, where surfaces or spaces are divided into smaller repeating shapes or units to create aesthetic and functional structures. Structural tessellation offers various advantages, including improved stability, increased load-bearing capacity, and enhanced aesthetic appeal. The growing use of digital tools and advanced numerical algorithms has facilitated the creation of complex and intricate tessellations that can be tailored to suit specific project requirements. This research focuses on algorithmic methods for generating tessellations and their utilization in structural engineering and design optimization. Diverse patterns and configurations of tessellation are investigated through mesh generation algorithms, parametric approaches, and pattern gradation and repetitions, with data visualization accomplished using computing scripts and Grasshopper. The tessellation elements are employed to discretize the design domain in structural optimization and create initial patterns. The paper demonstrates the feasibility of proposed frameworks for structural design and application through the examination of various numerical examples. In conclusion, the strategic use of structural tessellation proves to be effective in producing unique and functional structures that seamlessly combine visual appeal with material and resource efficiency.