590 results on '"Chong, W."'
Search Results
2. Achieving eco-innovative smart glass design with the integration of opinion mining, QFD and TRIZ
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Lee, C. K. M., Tsang, Y. P., Chong, W. W., Au, Y. S., and Liang, J. Y.
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- 2024
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3. Whole genome sequencing data of multiple individuals of Pakistani descent
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Khan, Shahid Y, Ali, Muhammad, Lee, Mei-Chong W, Ma, Zhiwei, Biswas, Pooja, Khan, Asma A, Naeem, Muhammad Asif, Riazuddin, Saima, Riazuddin, Sheikh, Ayyagari, Radha, Hejtmancik, J Fielding, and Riazuddin, S Amer
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Human Genome ,Genetics ,Genome ,Human ,Humans ,Pakistan ,Polymorphism ,Single Nucleotide ,Whole Genome Sequencing - Abstract
Here we report whole genome sequencing of four individuals (H3, H4, H5, and H6) from a family of Pakistani descent. Whole genome sequencing yielded 1084.92, 894.73, 1068.62, and 1005.77 million mapped reads corresponding to 162.73, 134.21, 160.29, and 150.86 Gb sequence data and 52.49x, 43.29x, 51.70x, and 48.66x average coverage for H3, H4, H5, and H6, respectively. We identified 3,529,659, 3,478,495, 3,407,895, and 3,426,862 variants in the genomes of H3, H4, H5, and H6, respectively, including 1,668,024 variants common in the four genomes. Further, we identified 42,422, 39,824, 28,599, and 35,206 novel variants in the genomes of H3, H4, H5, and H6, respectively. A major fraction of the variants identified in the four genomes reside within the intergenic regions of the genome. Single nucleotide polymorphism (SNP) genotype based comparative analysis with ethnic populations of 1000 Genomes database linked the ancestry of all four genomes with the South Asian populations, which was further supported by mitochondria based haplogroup analysis. In conclusion, we report whole genome sequencing of four individuals of Pakistani descent.
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- 2020
4. Research on the adaptability of energy management to thermal management of PEMFCs.
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Luo, Y, Ali, M A H, Ghazali, N N N, Chong, W T, Liu, H C, Chen, H, and Zhang, S K
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- 2024
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5. Framework design of recycling system for expired medicine and waste batteries in Chinese community.
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Zhang, M R and Chong, W T
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- 2024
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6. Experimental investigation into the effects of endplate designs for a Savonius turbine.
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Wong, K H, Foo, J S Y, Chong, W T, Mat, S, and Ng, J H
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- 2024
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7. Identification of novel transcripts and peptides in developing murine lens.
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Khan, Shahid Y, Ali, Muhammad, Kabir, Firoz, Chen, Ruiqiang, Na, Chan Hyun, Lee, Mei-Chong W, Pourmand, Nader, Hackett, Sean F, and Riazuddin, S Amer
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Lens ,Crystalline ,Animals ,Mice ,Peptides ,Proteome ,RNA Splice Sites ,Chromatography ,Liquid ,Sequence Analysis ,RNA ,Alternative Splicing ,Organogenesis ,Pregnancy ,Introns ,Exons ,Algorithms ,Databases ,Genetic ,Female ,Tandem Mass Spectrometry ,High-Throughput Nucleotide Sequencing ,Transcriptome ,Chromatography ,Liquid ,Databases ,Genetic ,Lens ,Crystalline ,Sequence Analysis ,RNA - Abstract
We previously investigated the transcriptome and proteome profiles of the murine ocular lens at six developmental time points including two embryonic (E15 and E18) and four postnatal time points (P0, P3, P6, and P9). Here, we extend our analyses to identify novel transcripts and peptides in developing mouse lens. We identified a total of 9,707 novel transcripts and 325 novel fusion genes in developing mouse lens. Additionally, we identified 13,281 novel alternative splicing (AS) events in mouse lens including 6,990 exon skipping (ES), 2,447 alternative 3' splice site (A3SS), 1,900 alternative 5' splice site (A5SS), 1,771 mutually exclusive exons (MXE), and 173 intron retention (IR). Finally, we integrated our OMIC (Transcriptome and Proteome) datasets identifying 20 novel peptides in mouse lens. All 20 peptides were validated through matching MS/MS spectra of synthetic peptides. To the best of our knowledge, this is the first report integrating OMIC datasets to identify novel peptides in developing murine lens.
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- 2018
8. Hypothermia for moderate or severe neonatal encephalopathy in low-income and middle-income countries (HELIX): a randomised controlled trial in India, Sri Lanka, and Bangladesh
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Thayyil, Sudhin, Pant, Stuti, Montaldo, Paolo, Shukla, Deepika, Oliveira, Vania, Ivain, Phoebe, Bassett, Paul, Swamy, Ravi, Mendoza, Josephine, Moreno-Morales, Maria, Lally, Peter J., Benakappa, Naveen, Bandiya, Prathik, Shivarudhrappa, Indramma, Somanna, Jagadish, Kantharajanna, Usha B., Rajvanshi, Ankur, Krishnappa, Sowmya, Joby, Poovathumkal K., Jayaraman, Kumutha, Chandramohan, Rema, Kamalarathnam, Chinnathambi N., Sebastian, Monica, Tamilselvam, Indumathi, Rajendran, Ushadevi, Soundrarajan, Radhakrishnan, Kumar, Vignesh, Sudarsanan, Harish, Vadakepat, Padmesh, Gopalan, Kavitha, Sundaram, Mangalabharathi, Seeralar, Arasar, Vinayagam, Prakash, Sajjid, Mohamed, Baburaj, Mythili, Murugan, Kanchana D., Sathyanathan, Babu P., Kumaran, Elumalai S., Mondkar, Jayashree, Manerkar, Swati, Joshi, Anagha R., Dewang, Kapil, Bhisikar, Swapnil M., Kalamdani, Pavan, Bichkar, Vrushali, Patra, Saikat, Jiwnani, Kapil, Shahidullah, Mohammod, Moni, Sadeka C., Jahan, Ismat, Mannan, Mohammad A., Dey, Sanjoy K., Nahar, Mst. N., Islam, Mohammad N, Shabuj, Kamrul H, Rodrigo, Ranmali, Sumanasena, Samanmali, Abayabandara-Herath, Thilini, Chathurangika, Gayani K, Wanigasinghe, Jithangi, Sujatha, Radhika, Saraswathy, Sobhakumar, Rahul, Aswathy, Radha, Saritha J, Sarojam, Manoj K., Krishnan, Vaisakh, Nair, Mohandas K., Devadas, Sahana, Chandriah, Savitha, Venkateswaran, Harini, Burgod, Constance, Chandrasekaran, Manigandan, Atreja, Gaurav, Muraleedharan, Pallavi, Herberg, Jethro A., Chong, WK 'Kling', Sebire, Neil J., Pressler, Ronit, Ramji, Siddarth, Shankaran, Seetha, Lally, Peter J, Kantharajanna, Usha B, Joby, Poovathumkal K, Kamalarathnam, Chinnathambi N, Tamilselvam, Indumathi A, Rajendran, Usha D, Murugan, Kanchana D, Sathyanathan, Babu P, Kumaran, Elumalai S, Joshi, Anagha R, Bhisikar, Swapnil M, Moni, Sadeka C, Mannan, Mohammad A, Dey, Sanjoy K, Nahar, Mst N, Sarojam, Manoj K, Nair, Mohandas K, Herberg, Jethro A, Kling Chong, W K, and Sebire, Neil J
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- 2021
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9. FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1.
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Khan, Shahid Y, Vasanth, Shivakumar, Kabir, Firoz, Gottsch, John D, Khan, Arif O, Chaerkady, Raghothama, Lee, Mei-Chong W, Leitch, Carmen C, Ma, Zhiwei, Laux, Julie, Villasmil, Rafael, Khan, Shaheen N, Riazuddin, Sheikh, Akram, Javed, Cole, Robert N, Talbot, C Conover, Pourmand, Nader, Zaghloul, Norann A, Hejtmancik, J Fielding, and Riazuddin, S Amer
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Lens ,Crystalline ,Epithelial Cells ,Animals ,Zebrafish ,Humans ,Corneal Opacity ,Eye Abnormalities ,Gene Expression Profiling ,Pedigree ,Gene Expression Regulation ,Family Health ,Autophagy ,Female ,Male ,HSP40 Heat-Shock Proteins ,Forkhead Transcription Factors ,Gene Knockdown Techniques ,HEK293 Cells ,Whole Exome Sequencing ,Eye Disease and Disorders of Vision ,Genetics ,2.1 Biological and endogenous factors ,Lens ,Crystalline ,MD Multidisciplinary - Abstract
FOXE3 is a lens-specific transcription factor that has been associated with anterior segment ocular dysgenesis. To determine the transcriptional target(s) of FOXE3 that are indispensable for the anterior segment development, we examined the transcriptome and the proteome of cells expressing truncated FOXE3 responsible for Peters anomaly identified through linkage-coupled next-generation whole-exome sequencing. We found that DNAJB1, an autophagy-associated protein, was the only candidate exhibiting differential expression in both screens. We confirmed the candidacy of DNAJB1 through chromatin immunoprecipitation and luciferase assays while knockdown of DNAJB1 in human lens epithelial cells resulted in a mitotic arrest. Subsequently, we targeted dnajb1a in zebrafish through injection of a splice-blocking morpholino. The dnajb1a morphants exhibited underdeveloped cataractous lenses with persistent apoptotic nuclei. In conclusion, here we report DNAJB1 is a transcriptional target of FOXE3 in a novel pathway that is crucial for the development of the anterior segment of the eye.
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- 2016
10. Transcriptome Profiling of Developing Murine Lens Through RNA SequencingDeveloping Mouse Lens Transcriptome
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Khan, Shahid Y, Hackett, Sean F, Lee, Mei-Chong W, Pourmand, Nader, Talbot, C Conover, and Riazuddin, S Amer
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Biomedical and Clinical Sciences ,Ophthalmology and Optometry ,Eye Disease and Disorders of Vision ,Genetics ,Pediatric ,Human Genome ,Biotechnology ,Underpinning research ,1.1 Normal biological development and functioning ,Animals ,Animals ,Newborn ,Cataract ,Computational Biology ,Disease Models ,Animal ,Female ,Gene Expression Profiling ,Gene Library ,High-Throughput Nucleotide Sequencing ,Lens ,Crystalline ,Mice ,Organogenesis ,Pregnancy ,Pregnancy ,Animal ,RNA ,Messenger ,next-generation sequencing ,transcriptome ,lens development ,mRNA ,miRNA ,Biological Sciences ,Medical and Health Sciences ,Ophthalmology & Optometry ,Ophthalmology and optometry - Abstract
PurposeTranscriptome is the entire repertoire of transcripts present in a cell at any particular time. We undertook a next-generation whole transcriptome sequencing approach to gain insight into the transcriptional landscape of the developing mouse lens.MethodsWe ascertained mouse lenses at six developmental time points including two embryonic (E15 and E18) and four postnatal stages (P0, P3, P6, and P9). The ocular tissue at each time point was maintained as two distinct pools serving as biological replicates for each developmental stage. The mRNA and small RNA libraries were paired-end sequenced on Illumina HiSeq 2000 and subsequently analyzed using bioinformatics tools.ResultsMapping of mRNA and small RNA libraries generated 187.56 and 154.22 million paired-end reads, respectively. We detected a total of 14,465 genes in the mouse ocular lens at the above-mentioned six developmental stages. Of these, 46 genes exhibited a 40-fold differential (higher or lower) expression at one the five developmental stages (E18, P0, P3, P6, and P9) compared with their expression level at E15. Likewise, small RNA profiling identified 379 microRNAs (miRNAs) expressed in mouse lens at six developmental time points. Of these, 49 miRNAs manifested an 8-fold differential (higher or lower) expression at one the five developmental stages, as mentioned above compared with their expression level at E15.ConclusionsWe report a comprehensive profile of developing murine lens transcriptome including both mRNA and miRNA through next-generation RNA sequencing. A complete repository of the lens transcriptome of six developmental time points will be monumental in elucidating processes essential for the development of the ocular lens and maintenance of its transparency.
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- 2015
11. A Multi-Level Dynamic Instructional Planner for an Intelligent Physiology Tutoring System.
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Illinois Inst. of Tech., Chicago. and Woo, Chong W.
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This paper describes the design and development of an instructional planner for an intelligent tutoring system for cardiovascular physiology that assists medical students to learn the causal relationships between the parameters of the circulatory system, to understand how a negative feedback system works, and to solve problems involving disturbances to the system. The instructional planner is responsible for deciding what to do at each point during a tutoring session. It integrates opportunistic control with sophisticated instructional planning, combining lesson planning with discourse planning. The lesson planning is organized in three levels: goal generation, determination of planning strategies, and choice of tactics to refine the goal into subgoals. The mixed-initiative discourse planning is implemented using a two-level approach: pedagogical decision making at the upper level and tactical discourse state-based planning at the lower level in its discourse management network. It generates plans dynamically based on the student model, monitors their execution, repairs plans when necessary, and replans when the student asks a question or makes a comment. (Contains 49 references.) (Author)
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- 1992
12. American Telemedicine Association’s Principles for Delivering Telerehabilitation Services
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Tammy Richmond, Christopher Peterson, Jana Cason, Mike Billings, Evelyn Abrahante Terrell, Alan Chong W. Lee, Michael Towey, Bambang Parmanto, Andi Saptano, Ellen R. Cohn, and David Brennan
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Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Telehealth is a broad term used to describe the use of electronic or digital information and communications technologies to support clinical healthcare, patient and professional health related education, and public health and health administration. Telerehabilitation refers to the delivery of rehabilitation and habilitation services via information and communication technologies (ICT), also commonly referred to as” telehealth” technologies. Telerehabilitation services can include evaluation, assessment, monitoring, prevention, intervention, supervision, education, consultation, and coaching. Telerehabilitation services can be deployed across all patient populations and multiple healthcare settings including clinics, homes, schools, or community-based worksites. This document was adapted from the American Telemedicine Association’s (ATA) “A Blueprint for Telerehabilitation Guidelines” (2010) and reflects the current utilization of telerehabilitation services. It was developed collaboratively by members of the ATA Telerehabilitation Special Interest Group, with input and guidance from other practitioners in the field, strategic stakeholders, and ATA staff. Its purpose is to inform and assist practitioners in providing effective and secure services that are based on client needs, current empirical evidence, and available technologies. Rehabilitation professionals, in conjunction with professional associations and other organizations are encouraged to use this document as a resource for developing discipline-specific standards, guidelines, and practice requirements. Keywords: American Telemedicine Association, Habilitation, Rehabilitation, Telehealth, Telepractice
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- 2017
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13. Clinician's Commentary on O'Neil. et al.
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Lee, Alan Chong W., primary
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- 2023
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14. The Effects of Hydroxyapatite Nanoparticles on the Growth and Yield of Ginger (Zingiber officinale Roscoe) from Seedling to Tillering Stage
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Chong, W X, primary, Kiew, W Y, additional, Low, Y C, additional, Lim, T H, additional, and Tan, H Y, additional
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- 2023
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15. Strength Characteristics of Clay Soil Admixed with Sand and Ca-based Stabiliser for Reduced Carbon Emissions.
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Chong, W-A, Chan, C-M, Cheong, P-C, Sani, S, and Yahya, N F
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- 2023
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16. FOXE3 contributes to Peters anomaly through transcriptional regulation of an autophagy-associated protein termed DNAJB1
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Shahid Y. Khan, Shivakumar Vasanth, Firoz Kabir, John D. Gottsch, Arif O. Khan, Raghothama Chaerkady, Mei-Chong W. Lee, Carmen C. Leitch, Zhiwei Ma, Julie Laux, Rafael Villasmil, Shaheen N. Khan, Sheikh Riazuddin, Javed Akram, Robert N. Cole, C. Conover Talbot, Nader Pourmand, Norann A. Zaghloul, J. Fielding Hejtmancik, and S. Amer Riazuddin
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Science - Abstract
Peter's Anomaly is a developmental disorder of the eye and has been linked to mutations in a range of genes, including the transcription factor FOXE3. Here the authors use next-generation RNA sequencing and mass spectrometry to identify an autophagy-associated protein, DNAJB1 as the transcriptional target of FOXE3.
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- 2016
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17. The characteristics of necessity, commoner and parasite with multicultural data comparison
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Kim, Chong W, Song, Young Hack, and Kim, Nam Hyeon
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- 2014
18. Abstract 20632: Fat Depots From Melanocortin Type 4 Receptor Knock Out and Diet-Induced Obese Mice Contribute Differentially to Cytokine Production During Obese Inflammatory Response
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Savio-Galimberti, Eleonora, Qiang, Guifen, Gil, Victoria, and Liew, Chong W
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- 2017
19. Common Artifacts in Magnetic Resonance Imaging: A Pictorial Essay.
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Ho, C. H., Xiao, L., Kwok, K. Y., Yang, S., Fung, B. W. H., Yu, K. C. H., Chong, W. H., Yeung, T. W., and Li, A.
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- 2023
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20. Feasibility analysis of a hybrid off-grid wind–DG-battery energy system for the eco-tourism remote areas
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Shezan, SK. A., Saidur, R., Ullah, K. R., Hossain, A., Chong, W. T., and Julai, S.
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- 2015
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21. Pyridoxine-Dependent Seizures: A Family Phenotype that Leads to Severe Cognitive Deficits, Regardless of Treatment Regime
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Rankin, Peter M, Harrison, Sue, and Chong, W. K.
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The neuropsychological and clinical histories of three male siblings affected by pyridoxine-dependent seizures with known homozygous antiquitin mutations are presented. Neuropsychological evaluation is reported from when the siblings were 11, 9, and 7 years of age. Two of the siblings had received early pyridoxine treatment (antenatal, 2-4 wks into pregnancy) and one had received late treatment (2 mo postnatal). However, there was no differential effect on cognitive outcome, with all three siblings having moderate to severe learning disability. Unlike previously reported cases that received early postnatal treatment, none of the siblings had relatively preserved non-verbal cognitive skills. Equally, their intellectual performance over time did not increase above the 1st centile despite high maintenance doses of vitamin B6 (range 16-26 mg/kg/d), and mild sensory neuropathy was reported on nerve conduction studies. The findings in these siblings challenge assumptions that early and high dose pyridoxine treatment can benefit cognition in this population and suggest routine electromyography monitoring may be beneficial. (Contains 2 tables and 2 figures.)
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- 2007
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22. COVID-19 and Post-intensive Care Syndrome: Community-Based Care for ICU Survivors
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Hallie Zeleznik, Patricia J. Ohtake, Ellen M.T. Smith, Alan Chong W. Lee, James M. Smith, and Alecia Thiele
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Community and Home Care ,endocrine system ,medicine.medical_specialty ,Rehabilitation ,Coronavirus disease 2019 (COVID-19) ,Leadership and Management ,business.industry ,medicine.medical_treatment ,Public Health, Environmental and Occupational Health ,Cognition ,biochemical phenomena, metabolism, and nutrition ,medicine.disease_cause ,Mental health ,Post-intensive care syndrome ,03 medical and health sciences ,0302 clinical medicine ,030228 respiratory system ,Critical illness ,medicine ,030212 general & internal medicine ,Intensive care medicine ,business ,Community-based care ,Coronavirus - Abstract
Survivors of critical illness, including those with COVID-19, are likely to experience post-intensive care syndrome (PICS). PICS involves a constellation of physical, cognitive, and mental health problems that can occur following hospitalization in an intensive care unit (ICU). This focused review describes the impact of PICS on an individual’s function, societal participation, and family. Specific evidence-based screening tools for in-home identification of the deficits associated with PICS are recommended. Recognition of PICS through early screening by home health care providers is crucial in order to assemble the physical rehabilitation, mental health, and community resources needed to mitigate the long-term effects of COVID-19 and other critical illnesses. This review concludes with further PICS resources for community-based providers to enhance their knowledge and expertise and to prepare them for caring for COVID-19 and other critical illness survivors.
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- 2020
23. The key characteristics of different types of employees: a summary of six studies
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Kim, Chong W., Smith, Harlan M., II, Sikula, Andrew, Sr, and Anderson, Lorraine P.
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- 2011
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24. Identification of a human synaptotagmin-1 mutation that perturbs synaptic vesicle cycling
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Baker, Kate, Gordon, Sarah L., Grozeva, Detelina, van Kogelenberg, Margriet, Roberts, Nicola Y., Pike, Michael, Blair, Edward, Hurles, Matthew E., Chong, W. Kling, Baldeweg, Torsten, Kurian, Manju A., Boyd, Stewart G., Cousin, Michael A., and Raymond, F. Lucy
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Genetic variation -- Health aspects ,Cellular proteins -- Health aspects ,Cellular control mechanisms -- Genetic aspects ,Health care industry - Abstract
Synaptotagmin-1 (SYT1) is a calcium-binding synaptic vesicle protein that is required for both exocytosis and endocytosis. Here, we describe a human condition associated with a rare variant in SYT1. The individual harboring this variant presented with an early onset dyskinetic movement disorder, severe motor delay, and profound cognitive impairment. Structural MRI was normal, but EEG showed extensive neurophysiological disturbances that included the unusual features of low-frequency oscillatory bursts and enhanced paired-pulse depression of visual evoked potentials. Trio analysis of whole- exome sequence identified a de novo SYT1 missense variant (I368T). Expression of rat SYT1 containing the equivalent human variant in WT mouse primary hippocampal cultures revealed that the mutant form of SYT1 correctly localizes to nerve terminals and is expressed at levels that are approximately equal to levels of endogenous WT protein. The presence of the mutant SYT1 slowed synaptic vesicle fusion kinetics, a finding that agrees with the previously demonstrated role for I368 in calcium-dependent membrane penetration. Expression of the I368T variant also altered the kinetics of synaptic vesicle endocytosis. Together, the clinical features, electrophysiological phenotype, and in vitro neuronal phenotype associated with this dominant negative SYT1 mutation highlight presynaptic mechanisms that mediate human motor control and cognitive development., Introduction Many postsynaptic genes and processes have been linked to neurodevelopmental disorders (1), and it is increasingly apparent that presynaptic dysfunction is another major contributory pathway. Rare variants have been [...]
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- 2015
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25. Impact of COVID-19 on the imaging diagnosis of cardiac disease in Europe
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Williams M. C., Shaw L., Hirschfeld C. B., Maurovich-Horvat P., Norgaard B. L., Pontone G., Jimenez-Heffernan A., Sinitsyn V., Sergienko V., Ansheles A., Bax J. J., Buechel R., Milan E., Slart R. H. J. A., Nicol E., Bucciarelli-Ducci C., Pynda Y., Better N., Cerci R., Dorbala S., Raggi P., Villines T. C., Vitola J., Malkovskiy E., Goebel B., Cohen Y., Randazzo M., Pascual T. N. B., Dondi M., Paez D., Einstein A. J., Nasery M. N., Goda A., Shirka E., Benlabgaa R., Bouyoucef S., Medjahedi A., Nailli Q., Agolti M., Aguero R. N., Del Carmen Alak M., Alberguina L. G., Arronada G., Astesiano A., Norton C. B., Benteo P., Blanco J., Bonelli J. M., Bustos J. J., Cabrejas R., Cachero J., Campisi R., Canderoli A., Carames S., Carrascosa P., Castro R., Cendoya O., Cognigni L. M., Collaud C., Cortes C., Courtis J., Cragnolino D., Daicz M., De La Vega A., De Maria S. T., Del Riego H., Dettori F., Deviggiano A., Dragonetti L., Embon M., Enriquez R. E., Ensinas J., Faccio F., Facello A., Garofalo D., Geronazzo R., Gonza N., Gutierrez L., Guzzo M. A., Hasbani V., Huerin M., Jager V., Lewkowicz J. M., De Munain M. N. A. L., Lotti J. M., Marquez A., Masoli O., Masoli O. H., Mastrovito E., Mayoraz M., Melado G. E., Mele A., Merani M. F., Meretta A. H., Molteni S., Montecinos M., Noguera E., Novoa C., Sueldo C. P., Ascani S. P., Pollono P., Pujol M. P., Radzinschi A., Raimondi G., Redruello M., Rodriguez M., Romero R. L., Acuna A. R., Rovaletti F., Miguel L. S., Solari L., Strada B., Traverso S., Traverzo S. S., Del Huerto Velazquez Espeche M., Weihmuller J. S., Wolcan J., Zeffiro S., Sakanyan M., Beuzeville S., Boktor R., Butler P., Calcott J., Carr L., Chan V., Chao C., Chong W., Dobson M., Downie D., Dwivedi G., Elison B., Engela J., Francis R., Gaikwad A., Basavaraj A. G., Goodwin B., Greenough R., Hamilton-Craig C., Hsieh V., Joshi S., Lederer K., Lee K., Lee J., Magnussen J., Mai N., Mander G., Murton F., Nandurkar D., Neill J., O'Rourke E., O'Sullivan P., Pandos G., Pathmaraj K., Pitman A., Poulter R., Premaratne M., Prior D., Ridley L., Rutherford N., Salehi H., Saunders C., Scarlett L., Seneviratne S., Shetty D., Shrestha G., Shulman J., Solanki V., Stanton T., Stuart M., Stubbs M., Swainson I., Taubman K., Taylor A., Thomas P., Unger S., Upton A., Vamadevan S., Van Gaal W., Verjans J., Voutnis D., Wayne V., Wilson P., Wong D., Wong K., Younger J., Feuchtner G., Mirzaei S., Weiss K., Maroz-Vadalazhskaya N., Gheysens O., Homans F., Moreno-Reyes R., Pasquet A., Roelants V., Van De Heyning C. M., Rios R. A., Soldat-Stankovic V., Stankovic S., Siqueira M. H. A., Almeida A., Togni P. H. A., Andrade J. H., Andrade L., Anselmi C., Araujo R., Azevedo G., Bezerra S., Biancardi R., Grossman G. B., Brandao S., Pianta D. B., Carreira L., Castro B., Chang T., Cunali F., Cury R., Dantas R., De Amorim Fernandes F., De Lorenzo A., De MacEdo Filho R., Erthal F., Fernandes F., Fernandes J., De Souza T. F., Alves W. F., Ghini B., Goncalves L., Gottlieb I., Hadlich M., Kameoka V., Lima R., Lima A., Lopes R. W., E Silva R. M., Magalhaes T., Silva F. M., Mastrocola L. E., Medeiros F., Meneghetti J. C., Naue V., Naves D., Nolasco R., Nomura C., Oliveira J. B., Paixao E., De Carvalho F. P., Pinto I., Possetti P., Quinta M., Ramos R. R. N., Rocha R., Rodrigues A., Rodrigues C., Romantini L., Sanches A., Santana S., Da Silva L. S., Schvartzman P., Matushita C. S., Senra T., Shiozaki A., De Siqueira M. E. M., Siqueira C., Smanio P., Soares C. E., Soares J., Bittencourt M. S., Spiro B., Mesquita C. T., Torreao J., Torres R., Uellendahl M., Monte G. U., Verissimo O., Cabeda E. V., Pedras F. V., Waltrick R., Zapparoli M., Naseer H., Garcheva-Tsacheva M., Kostadinova I., Theng Y., Abikhzer G., Barette R., Chow B., Dabreo D., Friedrich M., Garg R., Hafez M. N., Johnson C., Kiess M., Leipsic J., Leung E., Miller R., Oikonomou A., Probst S., Roifman I., Small G., Tandon V., Trivedi A., White J., Zukotynski K., Canessa J., Munoz G. C., Concha C., Hidalgo P., Lovera C., Massardo T., Vargas L. S., Abad P., Arturo H., Ayala S., Benitez L., Cadena A., Caicedo C., Moncayo A. C., Gomez S., Villamil C. T. G., Jaimes C., Londono J., Blair J. L. L., Pabon L., Pineda M., Rojas J. C., Ruiz D., Escobar M. V., Vasquez A., Vergel D., Zuluaga A., Gamboa I. B., Castro G., Gonzalez U., Baric A., Batinic T., Franceschi M., Hrabak M., Jukic M., Medakovic P., Persic V., Prpic M., Punda A., Batista J. F., Lauchy J. M. G., Gutierrez Y. M., Menendez R., Peix A., Rochela L., Panagidis C., Petrou I., Engelmann V., Kaminek M., Kincl V., Lang O., Simanek M., Abdulla J., Bottcher M., Christensen M., Gormsen L. C., Hasbak P., Hess S., Holdgaard P., Johansen A., Kyhl K., Ovrehus K. A., Sand N. P. R., Steffensen R., Thomassen A., Zerahn B., Perez A., Velez G. A. E., Velez M. S., Aziz I. S. A., Abougabal M., Ahmed T., Allam A., Asfour A., Hassan M., Hassan A., Ibrahim A., Kaffas S., Kandeel A., Ali M. M., Mansy A., Maurice H., Nabil S., Shaaban M., Flores A. C., Poksi A., Knuuti J., Kokkonen V., Larikka M., Uusitalo V., Bailly M., Burg S., Deux J. -F., Habouzit V., Hyafil F., Lairez O., Proffit F., Regaieg H., Sarda-Mantel L., Tacher V., Schneider R. 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Cavenaghi, G, Chierichetti, F, Chiocchi, M, Cittanti, C, Colletta, M, Conti, U, Cossu, A, Cuocolo, A, Cuzzocrea, M, De Rimini, M, De Vincentis, G, Del Giudice, E, Del Torto, A, Della Tommasina, V, Durmo, R, Erba, P, Evangelista, L, Faletti, R, Faragasso, E, Farsad, M, Ferro, P, Florimonte, L, Frantellizzi, V, Fringuelli, F, Gatti, M, Gaudiano, A, Gimelli, A, Giubbini, R, Giuffrida, F, Ialuna, S, Laudicella, R, Leccisotti, L, Leva, L, Liga, R, Liguori, C, Longo, G, Maffione, M, Mancini, M, Marcassa, C, Nardi, B, Pacella, S, Pepe, G, Pulizzi, S, Quartuccio, N, Rampin, L, Ricci, F, Rossini, P, Rubini, G, Russo, V, Sacchetti, G, Sambuceti, G, Scarano, M, Sciagra, R, Sperandio, M, Stefanelli, A, Ventroni, G, Zoboli, S, Baugh, D, Chambers, D, Madu, E, Nunura, F, Asano, H, Chimura, C, Fujimoto, S, Fujisue, K, Fukunaga, T, Fukushima, Y, Fukuyama, K, Hashimoto, J, Ichikawa, Y, Iguchi, N, Imai, M, Inaki, A, Ishimura, H, Isobe, S, Kadokami, T, Kato, T, Kudo, T, Kumita, S, Maruno, H, Mataki, H, Miyagawa, M, Morimoto, R, Moroi, M, Nagamachi, S, Nakajima, K, Nakata, T, Nakazato, R, Nanasato, M, Naya, M, Norikane, T, Ohta, Y, Okayama, S, Okizaki, A, Otomi, Y, Otsuka, H, Saito, M, Sakata, S, Sarai, M, Sato, D, Shiraishi, S, Suwa, Y, Takanami, K, Takehana, K, Taki, J, Tamaki, N, Taniguchi, Y, Teragawa, H, Tomizawa, N, Tsujita, K, Umeji, K, Wakabayashi, Y, Yamada, S, Yamazaki, S, Yoneyama, T, Rawashdeh, M, Batyrkhanov, D, Dautov, T, Makhdomi, K, Ombati, K, Alkandari, F, Garashi, M, Coie, T, Rajvong, S, Kalinin, A, Kalnina, M, Haidar, M, Komiagiene, R, Kviecinskiene, G, Mataciunas, M, Vajauskas, D, Picard, C, Karim, N, Reichmuth, L, Samuel, A, Allarakha, M, Naojee, A, Alexanderson-Rosas, E, Barragan, E, Becerril, A, Gonzalez-Montecinos, Cabada, M, Rodriguez, D, Carvajal-Juarez, I, Cortes, V, Cortes, F, De La Pena, E, Gama-Moreno, M, Gonzalez, L, Ramirez, N, Jimenez-Santos, M, Matos, L, Monroy, E, Morelos, M, Ornelas, M, Ramirez, J, Preciado-Anaya, A, Preciado-Gutierrez, O, Barragan, A, Uvera, S, Sandoval, S, Tomas, M, Sierra-Galan, L, Siu, S, Vallejo, E, Valles, M, Faraggi, M, Sereegotov, E, Ilic, S, Ben-Rais, N, Alaoui, N, Taleb, S, Myo, K, Thu, P, Ghimire, R, Rajbanshi, B, Barneveld, P, Glaudemans, A, Habets, J, Koopmans, K, Manders, J, Pool, S, Scholte, A, Scholtens, A, Thimister, P, Van Asperen, E, Veltman, N, Verschure, D, Wagenaar, N, Edmond, J, Ellis, C, Johnson, K, Keenan, R, Kueh, S, Occleshaw, C, Sasse, A, To, A, Van Pelt, N, Young, C, Cuadra, T, Vanegas, H, Soli, I, Issoufou, D, Ayodele, T, Madu, C, Onimode, Y, Efros-Monsen, E, Forsdahl, S, Dimmen, J, Jorgensen, A, Krohn, I, Lovhaugen, P, Braten, A, Al Dhuhli, H, Al Kindi, F, Al-Bulushi, N, Jawa, Z, Tag, N, Afzal, M, Fatima, S, Younis, M, Riaz, M, Saadullah, M, Herrera, Y, Lenturut-Katal, D, Vazquez, M, Ortellado, J, Akhter, A, Cao, D, Cheung, S, Dai, X, Gong, L, Han, D, Hou, Y, Li, C, Li, T, Li, D, Li, S, Liu, J, Liu, H, Lu, B, Ng, M, Sun, K, Tang, G, Wang, J, Wang, X, Wang, Z, Wang, Y, Wu, J, Wu, Z, Xia, L, Xiao, J, Xu, L, Yang, Y, Yin, W, Yu, J, Yuan, L, Zhang, T, Zhang, L, Zhang, Y, Zhang, X, Zhu, L, Alfaro, A, Abrihan, P, Barroso, A, Cruz, E, Gomez, M, Magboo, V, Medina, J, Obaldo, J, Pastrana, D, Pawhay, C, Quinon, A, Tang, J, Tecson, B, Uson, K, Uy, M, Kostkiewicz, M, Kunikowska, J, Bettencourt, N, Cantinho, G, Ferreira, A, Syed, G, Arnous, S, Atyani, S, Byrne, A, Gleeson, T, Kerins, D, Meehan, C, Murphy, D, Murphy, M, Murray, J, O'Brien, J, Bang, J, Bom, H, Cho, S, Hong, C, Jang, S, Jeong, Y, Kang, W, Kim, J, Namgung, C, So, Y, Won, K, Majstorov, V, Vavlukis, M, Salobir, B, Stalc, M, Benedek, T, Benedek, I, Mititelu, R, Stan, C, Dariy, O, Drozdova, O, Gagarina, N, Gulyaev, V, Itskovich, I, Karalkin, A, Kokov, A, Migunova, E, Pospelov, V, Ryzhkova, D, Saifullina, G, Sazonova, S, Shurupova, I, Trifonova, T, Ussov, W, Vakhromeeva, M, Valiullina, N, Zavadovsky, K, Zhuravlev, K, Alasnag, M, Okarvi, S, Saranovic, D, Keng, F, See, J, Sekar, R, Yew, M, Vondrak, A, Bejai, S, Bennie, G, Bester, R, Engelbrecht, G, Evbuomwan, O, Gongxeka, H, Vuuren, M, Kaplan, M, Khushica, P, Lakhi, H, Louw, L, Malan, N, Milos, K, Modiselle, M, More, S, Naidoo, M, Scholtz, L, Vangu, M, Aguade-Bruix, S, Blanco, I, Cabrera, A, Camarero, A, Casans-Tormo, I, Cuellar-Calabria, H, Flotats, A, Canamero, M, Garcia, M, Leta, R, Diaz, J, Lumbreras, L, Marquez-Cabeza, J, Martin, F, De Alegria, A, Medina, F, Canal, M, Peiro, V, Pubul-Nunez, V, Madrid, J, Rey, C, Perez, R, Ruiz, J, Hernandez, G, Sevilla, A, Zeidan, N, Nanayakkara, D, Udugama, C, Simonsson, M, Alkadhi, H, Burger, P, Ceriani, L, De Boeck, B, Grani, C, De Saint Lager Lucas, A, Kamani, C, Kawel-Boehm, N, Manka, R, Prior, J, Rominger, A, Vallee, J, Khiewvan, B, Premprabha, T, Thientunyakit, T, Sellem, A, Kir, K, Sayman, H, Sebikali, M, Muyinda, Z, Kmetyuk, Y, Korol, P, Mykhalchenko, O, Pliatsek, V, Satyr, M, Albalooshi, B, Anderson, J, Bedi, P, Biggans, T, Bularga, A, Bull, R, Burgul, R, Carpenter, J, Coles, D, Cusack, D, Deshpande, A, Dougan, J, Fairbairn, T, Farrugia, A, Gopalan, D, Gummow, A, Ramkumar, P, Hamilton, M, Harbinson, M, Hartley, T, Hudson, B, Joshi, N, Kay, M, Kelion, A, Khokhar, A, Kitt, J, Low, C, Mak, S, Marousa, N, Martin, J, Mcalindon, E, Menezes, L, Morgan-Hughes, G, Moss, A, Murray, A, Patel, D, Peebles, C, Pugliese, F, Rodrigues, J, Rofe, C, Sabharwal, N, Schofield, R, Semple, T, Sharma, N, Strouhal, P, Subedi, D, Topping, W, Tweed, K, Weir-Mccall, J, Abbara, S, Abbasi, T, Abbott, B, Abohashem, S, Abramson, S, Al-Abboud, T, Al-Mallah, M, Almousalli, O, Ananthasubramaniam, K, Kumar, M, Askew, J, Attanasio, L, Balmer-Swain, M, Bayer, R, Bernheim, A, Bhatti, S, Bieging, E, Blankstein, R, Bloom, S, Blue, S, Bluemke, D, Borges, A, Branch, K, Bravo, P, Brothers, J, Budoff, M, Bullock-Palmer, R, Burandt, A, Burke, F, Bush, K, Candela, C, Capasso, E, Cavalcante, J, Chang, D, Chatterjee, S, Chatzizisis, Y, Cheezum, M, Chen, T, Chen, J, Chen, M, Choi, A, Clarcq, J, Cordero, A, Crim, M, Danciu, S, Decter, B, Dhruva, N, Doherty, N, Doukky, R, Dunbar, A, Duvall, W, Edwards, R, Esquitin, K, Farah, H, Fentanes, E, Ferencik, M, Fisher, D, Fitzpatrick, D, Foster, C, Fuisz, T, Gannon, M, Gastner, L, Gerson, M, Ghoshhajra, B, Goldberg, A, Goldner, B, Gonzalez, J, Gore, R, Gracia-Lopez, S, Hage, F, Haider, A, Haider, S, Hamirani, Y, Hassen, K, Hatfield, M, Hawkins, C, Hawthorne, K, Heath, N, Hendel, R, Hernandez, P, Hill, G, Horgan, S, Huffman, J, Hurwitz, L, Iskandrian, A, Janardhanan, R, Jellis, C, Jerome, S, Kalra, D, Kaviratne, S, Kay, F, Kelly, F, Khalique, O, Kinkhabwala, M, Iii, G, Kircher, J, Kirkbride, R, Kontos, M, Kottam, A, Krepp, J, Layer, J, Lee, S, Leppo, J, Lesser, J, Leung, S, Lewin, H, Litmanovich, D, Liu, Y, Lopez-Mattei, J, Magurany, K, Markowitz, J, Marn, A, Matis, S, Mckenna, M, Mcrae, T, Mendoza, F, Merhige, M, Min, D, Moffitt, C, Moncher, K, Moore, W, Morayati, S, Morris, M, Mossa-Basha, M, Mrsic, Z, Murthy, V, Nagpal, P, Napier, K, Narula, J, Nelson, K, Nijjar, P, Osman, M, Parwani, P, Passen, E, Patel, A, Patil, P, Paul, R, Phillips, L, Polsani, V, Poludasu, R, Pomerantz, B, Porter, T, Prentice, R, Pursnani, A, Rabbat, M, Ramamurti, S, Rich, F, Luna, H, Robinson, A, Robles, K, Rodriguez, C, Rorie, M, Rumberger, J, Russell, R, Sabra, P, Sadler, D, Schemmer, M, Schoepf, U, Shah, S, Shah, N, Shanbhag, S, Sharma, G, Shayani, S, Shirani, J, Shivaram, P, Sigman, S, Simon, M, Slim, A, Smith, D, Smith, A, Soman, P, Srichai-Parsia, M, Streeter, J, Albert, T, Tawakol, A, Thomas, D, Thompson, R, Torbet, T, Trinidad, D, Ullery, S, Unzek, S, Uretsky, S, Vallurupalli, S, Verma, V, Waller, A, Wang, E, Ward, P, Weissman, G, Wesbey, G, White, K, Winchester, D, Wolinsky, D, Yost, S, Zgaljardic, M, Alonso, O, Beretta, M, Ferrando, R, Kapitan, M, Mut, F, Djuraev, O, Rozikhodjaeva, G, Ngoc, H, Mai, S, Nguyen, X, Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Translational Immunology Groningen (TRIGR), and Cardiovascular Centre (CVC)
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INCAPS COVID Investigators Group ,cardiac imaging techniques ,Settore MED/11 - Malattie dell'Apparato Cardiovascolare ,Practice Patterns ,Disease ,Cardiovascular ,coronary artery disease ,COVID-19 ,Cardiac Imaging Techniques ,Cardiologists ,Europe ,Health Care Surveys ,Healthcare Disparities ,Heart Diseases ,Humans ,Practice Patterns, Physicians' ,Predictive Value of Tests ,Gross domestic product ,Human health ,cardiovascular disease ,Pandemic ,Medicine ,cardiovascular imaging ,BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Interna medicina ,cardiac imaging technique ,Predictive value of tests ,Cardiology and Cardiovascular Medicine ,BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Infektologija ,cardiac disease ,Coronavirus disease 2019 (COVID-19) ,Independent predictor ,cardiac imaging ,NO ,Imaging diagnosis ,Diseases of the circulatory (Cardiovascular) system ,BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Internal Medicine ,Physicians' ,business.industry ,BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Infectology ,RC666-701 ,HOSPITALIZATIONS ,business ,Health Care Delivery, Economics and Global Health Care ,Demography - Abstract
ObjectivesWe aimed to explore the impact of the COVID-19 pandemic on cardiac diagnostic testing and practice and to assess its impact in different regions in Europe.MethodsThe online survey organised by the International Atomic Energy Agency Division of Human Health collected information on changes in cardiac imaging procedural volumes between March 2019 and March/April 2020. Data were collected from 909 centres in 108 countries.ResultsCentres in Northern and Southern Europe were more likely to cancel all outpatient activities compared with Western and Eastern Europe. There was a greater reduction in total procedure volumes in Europe compared with the rest of the world in March 2020 (45% vs 41%, p=0.003), with a more marked reduction in Southern Europe (58%), but by April 2020 this was similar in Europe and the rest of the world (69% vs 63%, p=0.261). Regional variations were apparent between imaging modalities, but the largest reductions were in Southern Europe for nearly all modalities. In March 2020, location in Southern Europe was the only independent predictor of the reduction in procedure volume. However, in April 2020, lower gross domestic product and higher COVID-19 deaths were the only independent predictors.ConclusionThe first wave of the COVID-19 pandemic had a significant impact on care of patients with cardiac disease, with substantial regional variations in Europe. This has potential long-term implications for patients and plans are required to enable the diagnosis of non-COVID-19 conditions during the ongoing pandemic.
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- 2021
26. Diagnosis, management and prevention ofCandida aurisin hospitals: position statement of the Australasian Society for Infectious Diseases
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Rita Roy, Chong W. Ong, Catriona Halliday, Christopher H. Heath, Andrew J. Stewardson, Julia E Clark, Leon J Worth, Monica A. Slavin, Caroline Marshall, Deborah Marriott, Arthur J. Morris, Sarah E. Kidd, C. Orla Morrissey, and Sharon C.-A. Chen
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medicine.medical_specialty ,Antifungal Agents ,Antifungal drug ,Microbial Sensitivity Tests ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Drug Resistance, Fungal ,Amphotericin B ,Amphotericin B deoxycholate ,Disease Transmission, Infectious ,Internal Medicine ,Humans ,Medicine ,Infection control ,030212 general & internal medicine ,DNA, Fungal ,Intensive care medicine ,Fluconazole ,Societies, Medical ,Candida ,Cross Infection ,Infection Control ,business.industry ,Age Factors ,Australia ,Candidiasis ,Outbreak ,Candida auris ,Diagnosis management ,business ,New Zealand ,medicine.drug - Abstract
Candida auris is an emerging drug-resistant yeast responsible for hospital outbreaks. This statement reviews the evidence regarding diagnosis, treatment and prevention of this organism and provides consensus recommendations for clinicians and microbiologists in Australia and New Zealand. C. auris has been isolated in over 30 countries (including Australia). Bloodstream infections are the most frequently reported infections. Infections have crude mortality of 30-60%. Acquisition is generally healthcare-associated and risks include underlying chronic disease, immunocompromise and presence of indwelling medical devices. C. auris may be misidentified by conventional phenotypic methods. Matrix-assisted laser desorption ionisation time-of-flight mass spectrometry or sequencing of the internal transcribed spacer regions and/or the D1/D2 regions of the 28S ribosomal DNA are therefore required for definitive laboratory identification. Antifungal drug resistance, particularly to fluconazole, is common, with variable resistance to amphotericin B and echinocandins. Echinocandins are currently recommended as first-line therapy for infection in adults and children ≥2 months of age. For neonates and infants
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- 2019
27. Mutations at the BLK Locus Linked to Maturity Onset Diabetes of the Young and ß-Cell Dysfunction
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Borowiec, Maciej, Liew, Chong W., Thompson, Ryan, Boonyasrisawat, Watip, Hu, Jiang, Mlynarski, Wojciech M., Khattabi, Ilham El, Kim, Sung-Hoon, Marselli, Lorella, Rich, Stephen S., Krolewski, Andrzej S., Bonner-Weir, Susan, Sharma, Arun, Sale, Michele, Mychaleckyj, Josyf C., Kulkarni, Rohit N., Doria, Alessandro, and Kahn, C. Ronald
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- 2009
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28. SUCCESSFUL ECTOMYCORRHIZAL INOCULATION OF TWO DIPTEROCARP SPECIES WITH A LOCALLY ISOLATED FUNGUS IN PENINSULAR MALAYSIA
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Lee, S. S., Patahayah, M., Chong, W. S., and Lapeyrie, F.
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- 2008
29. Telehealth implementation in a skilled nursing facility: case report for physical therapist practice in Washington
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Lee, Alan Chong W. and Billings, Michael
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Therapeutics, Physiological -- Technology application ,Telemedicine -- Methods ,Physical therapy -- Technology application ,Health facilities -- Technology application ,Technology application ,Health - Abstract
Background and Purpose. Telehealth is defined as the delivery of health-related services and information via telecommunication technologies. The purposes of this case report are: (1) to describe the development, implementation, and evaluation of a telehealth approach for meeting physical therapist supervision requirements in a skilled nursing facility (SNF) in Washington and (2) to explore clinical and human factors of physical therapist practice in an SNF delivered via telehealth. Case Description. In 2009, Infinity Rehab conducted a pilot program to determine whether telehealth could be used to meet physical therapist supervision requirements in an SNF. In 2011, language allowing telehealth physical therapy was approved by the Washington Board of Physical Therapy (Board). In 2014-2015, telehealth outcomes were evaluated in a 51-person sample at an Infinity Rehab SNF. Cost savings of telehealth implementation from 2011 to 2015 were estimated. Outcomes. The Board deemed the telehealth pilot program a success and subsequently established telehealth practice language for physical therapy. Both human factors and clinical outcomes were required to implement a successful telehealth practice. Clinical outcomes and user satisfaction in telehealth and nontelehealth groups were equivalent. Cost savings were identified. Discussion. Human factors, such as the need for provider education in appropriate bedside manner with a telehealth session, were identified. Since 2011, more than 1,000 telehealth physical therapy sessions were conducted at Infinity Rehab SNFs in Washington State. In the future, alternative payment models focused on valued-based clinical outcomes may facilitate wider telehealth adoption in physical therapy. Future research on efficacy and cost-effectiveness is needed to promote broader adoption of telehealth physical therapy in SNFs. This experience demonstrates that telehealth implementation in an SNF for the purpose of physical therapy re-evaluation is a feasible alternative to in-person encounters., Telehealth is the use of secure electronic communications to provide and deliver a host of health-related information and health care services, including but not limited to physical therapy-related information and [...]
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- 2016
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30. A Model of Reasoned Responses: Use of the Golden Mean and Implications for Management Practice
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Kim, Chong W., McInerney, Margie, and Sr., Andrew Sikula,
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- 2004
31. Rosiglitazone Requires Hepatocyte PPARγ Expression to Promote Steatosis in Male Mice With Diet-Induced Obesity
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Lee, Samuel M, primary, Muratalla, Jose, additional, Diaz-Ruiz, Alberto, additional, Remon-Ruiz, Pablo, additional, McCann, Maximilian, additional, Liew, Chong W, additional, Kineman, Rhonda D, additional, and Cordoba-Chacon, Jose, additional
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- 2021
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32. The Effects of Glycopyrrolate as Premedication on Post-Operative Nausea and Vomiting: A Propensity Score Matching Analysis
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Sang W. Yoon, Chong W. Baek, Seung-Hyuk Lee, Yong Hee Park, Geun Joo Choi, Yong Hun Jung, Young Choel Woo, and Hyun Kang
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medicine.diagnostic_test ,Nausea ,business.industry ,030208 emergency & critical care medicine ,03 medical and health sciences ,0302 clinical medicine ,Anesthesiology and Pain Medicine ,030202 anesthesiology ,Anesthesia ,Propensity score matching ,medicine ,Vomiting ,Premedication ,Post operative ,medicine.symptom ,business ,Laparoscopy ,Glycopyrrolate ,Postoperative nausea and vomiting - Abstract
Background:Glycopyrrolate is often used as a premedication for anesthesia as it has anti-sialogogue and vagolytic effect. Patients undergoing laparoscopic gynecologic surgery have high-risk of Post-Operative Nausea and Vomiting (PONV).Objectives:This retrospective study investigates the effect of glycopyrrolate as a premedication for PONV in patients receiving fentanyl-based Intravenous (IV) Patient-Controlled Analgesia (PCA) after laparoscopic gynecological surgery.Methods:We reviewed the medical records of adult patients who received fentanyl-based IV-PCA after laparoscopic gynecological surgery at Chung-Ang University Hospital between January 1, 2010, and June 30, 2016. We classified patients into two groups on the basis of glycopyrrolate premedication: non-premedicated group (Group N; n = 316) and glycopyrrolate premedicated group (Group P; n = 434). The Propensity Score Matching Method (PSM) was used to select 157 subjects in Group N and P, on the basis of their covariates which were matched with a counterpart in the other group.Results:Prior to PSM, the necessities for rescue anti-emetics were lower on Postoperative Day (POD) 0 (58[18.4%]vs.45[10.4%],P= 0.002) and POD1 (60[19.0%]vs.59[13.6%],P= 0.046), and Visual Analogue Scale (VAS) of pain on POD 1 (2.86 ± 1.49vs.3.13 ± 1.53,P= 0.017) was higher in group P. After PSM, the Numerical Rating Scale (NRS) score for nausea (0.38 ± 0.75vs. 0.21 ± 0.62,P= 0.027) and rescue anti-emetics (27 [17.2%]vs. 15 [9.6%],P= 0.047) on POD 0 were both lower in the group P.Conclusion:In patients receiving fentanyl-based IV-PCA after laparoscopic gynecological surgery, the severity of nausea and necessity for rescue ant-emetic was lower in the glycopyrrolate premedication group.
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- 2019
33. Neonatal Hypoxia, Hippocampal Atrophy, and Memory Impairment: Evidence of a Causal Sequence
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Cooper, Janine M., Gadian, David G., Jentschke, Sebastian, Goldman, Allan, Munoz, Monica, Pitts, Georgia, Banks, Tina, Chong, W. Kling, Hoskote, Aparna, Deanfield, John, Baldeweg, Torsten, de Haan, Michelle, Mishkin, Mortimer, and Vargha-Khadem, Faraneh
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- 2015
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34. Generation and Metabolism of 5-lipoxygenase Pathway Leukotrienes by Human Eosinophils: Predominant Production of Leukotriene C 4
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Weller, Peter F., Lee, Chong W., Foster, Donald W., Corey, E. J., Austen, K. Frank, and Lewis, Robert A.
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- 1983
35. Oxidative Inactivation of Leukotriene C 4 by Stimulated Human Polymorphonuclear Leukocytes
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Lee, Chong W., Lewis, Robert A., Corey, E. J., Barton, Alan, Oh, Hunseung, Tauber, Alfred I., and Austen, K. Frank
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- 1982
36. Carbon Dioxide and Senescence in Cotton Plants
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Chang, Chong W.
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- 1975
37. Isolation and Purification of Leaf Starch Components
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Chang, Chong W.
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- 1979
38. Starch Depletion and Sugars in Developing Cotton Leaves
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Chang, Chong W.
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- 1980
39. Starch and Its Component Ratio in Developing Cotton Leaves
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Chang, Chong W.
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- 1979
40. Impact of COVID-19 Pandemic on Cardiovascular Testing in Asia: The IAEA INCAPS-COVID Study
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Kudo, T., Lahey, R., Hirschfeld, C.B., Williams, M.C., Lu, B., Alasnag, M., Bhatia, M., Henry Bom, H.-., Dautov, T., Fazel, R., Karthikeyan, G., Keng, F.Y.J., Rubinshtein, R., Better, N., Cerci, R.J., Dorbala, S., Raggi, P., Shaw, L.J., Villines, T.C., Vitola, J.V., Choi, A.D., Malkovskiy, E., Goebel, B., Cohen, Y.A., Randazzo, M., Pascual, T.N.B., Pynda, Y., Dondi, M., Paez, D., Einstein, A.J., Cerci, R., Hinterleitner, G., Lu, Y., Morozova, O., Xu, Z., Cohen, Y., Choi, A., Lopez-Mattei, J., Parwani, P., Nasery, M.N., Goda, A., Shirka, E., Benlabgaa, R., Bouyoucef, S., Medjahedi, A., Nailli, Q., Agolti, M., Aguero, R.N., Alak, M.D.C., Alberguina, L.G., Arronada, G., Astesiano, A., Norton, C.B., Benteo, P., Blanco, J., Bonelli, J.M., Bustos, J.J., Cabrejas, R., Cachero, J., Campisi, R., Canderoli, A., Carames, S., Carrascosa, P., Castro, R., Cendoya, O., Cognigni, L.M., Collaud, C., Cortes, C., Courtis, J., Cragnolino, D., Daicz, M., De La Vega, A., De Maria, S.T., Del Riego, H., Dettori, F., Deviggiano, A., Dragonetti, L., Embon, M., Enriquez, R.E., Ensinas, J., Faccio, F., Facello, A., Garofalo, D., Geronazzo, R., Gonza, N., Gutierrez, L., Guzzo, M.A., Hasbani, V., Huerin, M., Jager, V., Lewkowicz, J.M., Lopez De Munain, M.N.A., Lotti, J.M., Marquez, A., Masoli, O., Masoli, O.H., Mastrovito, E., Mayoraz, M., Melado, G.E., Mele, A., Merani, M.F., Meretta, A.H., Molteni, S., Montecinos, M., Noguera, E., Novoa, C., Sueldo, C.P., Ascani, S.P., Pollono, P., Pujol, M.P., Radzinschi, A., Raimondi, G., Redruello, M., Rodriguez, M., Romero, R.L., Acuna, A.R., Rovaletti, F., San Miguel, L., Solari, L., Strada, B., Traverso, S., Traverzo, S.S., Espeche, M.D.H.V., Weihmuller, J.S., Wolcan, J., Zeffiro, S., Sakanyan, M., Beuzeville, S., Boktor, R., Butler, P., Calcott, J., Carr, L., Chan, V., Chao, C., Chong, W., Dobson, M., Downie, D.A., Dwivedi, G., Elison, B., Engela, J., Francis, R., Gaikwad, A., Basavaraj, A.G., Goodwin, B., Greenough, R., Hamilton-Craig, C., Hsieh, 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INCAPS COVID Investigators Group ,Pediatric Research Initiative ,positron emission tomography ,CTA ,SARS-CoV-2 ,cardiac testing ,invasive coronary angiography ,Prevention ,coronavirus ,coronavirus disease-19 ,COVID-19 ,global health ,Settore MED/11 - Malattie dell'Apparato Cardiovascolare ,cardiac magnetic resonance ,cardiovascular disease ,NO ,transthoracic echocardiography ,PET ,Good Health and Well Being ,severe acute respiratory syndrome-coronavirus-2 ,TTE ,ICA ,CMR ,computed tomographic angiography - Abstract
BackgroundThe coronavirus disease-2019 (COVID-19) pandemic significantly affected management of cardiovascular disease around the world. The effect of the pandemic on volume of cardiovascular diagnostic procedures is not known.ObjectivesThis study sought to evaluate the effects of the early phase of the COVID-19 pandemic on cardiovascular diagnostic procedures and safety practices in Asia.MethodsThe International Atomic Energy Agency conducted a worldwide survey to assess changes in cardiovascular procedure volume and safety practices caused by COVID-19. Testing volumes were reported for March 2020 and April 2020 and were compared to those from March 2019. Data from 180 centers across 33 Asian countries were grouped into 4 subregions for comparison.ResultsProcedure volumes decreased by 47% from March 2019 to March 2020, showing recovery from March 2020 to April 2020 in Eastern Asia, particularly in China. The majority of centers cancelled outpatient activities and increased time per study. Practice changes included implementing physical distancing and restricting visitors. Although COVID testing was not commonly performed, it was conducted in one-third of facilities in Eastern Asia. The most severe reductions in procedure volumes were observed in lower-income countries, where volumes decreased 81% from March 2019 to April2020.ConclusionsThe COVID-19 pandemic in Asia caused significant reductions in cardiovascular diagnostic procedures, particularly in low-income countries. Further studies on effects of COVID-19 on cardiovascular outcomes and changes in care delivery are warranted.
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- 2021
41. Treatable Leigh-like encephalopathy presenting in adolescence
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Fassone, Elisa, Wedatilake, Yehani, DeVile, Catherine J, Chong, W Kling, Carr, Lucinda J, and Rahman, Shamima
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- 2013
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42. Effect of Fluoride on Nucleotides and Ribonucleic Acid in Germinating Corn Seedling Roots
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Chang, Chong W.
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- 1968
43. Exocellular Enzymes of Corn Roots
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Chang, Chong W. and Bandurski, Robert S.
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- 1964
44. Effects of X-Irradiation on the Activity of Some Hydrolytic and Respiratory Enzymes in Corn Seedling Roots
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Chang, Chong W.
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- 1966
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45. Comparative Growth of Barley Embryos In vitro and In vivo
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Chang, Chong W.
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- 1963
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46. The Silk Vista Baby – The UK experience
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Bhogal, P, primary, Makalanda, HLD, additional, Wong, K, additional, Keston, P, additional, Downer, J, additional, Du Plessis, JC, additional, Nania, A, additional, Simonato, D, additional, Fuschi, M, additional, Chong, W, additional, O’Reilly, S, additional, and Rennie, I, additional
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- 2021
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47. Vertical axis wind turbine with omni-directional-guide-vane for urban high-rise buildings
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Chong, W. T., Poh, S. C., Fazlizan, A., and Pan, K. C.
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- 2012
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48. Epilepsy due to PNPO mutations: genotype, environment and treatment affect presentation and outcome
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Mills, Philippa B., Camuzeaux, Stephane S.M., Footitt, Emma J., Mills, Kevin A., Gissen, Paul, Fisher, Laura, Das, Krishna B., Varadkar, Sophia M., Zuberi, Sameer, McWilliam, Robert, Stödberg, Tommy, Plecko, Barbara, Baumgartner, Matthias R., Maier, Oliver, Calvert, Sophie, Riney, Kate, Wolf, Nicole I., Livingston, John H., Bala, Pronab, Morel, Chantal F., Feillet, François, Raimondi, Francesco, Del Giudice, Ennio, Chong, W. Kling, Pitt, Matthew, and Clayton, Peter T.
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- 2014
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49. Mutations at the BLK locus linked to maturity onset diabetes of the young and [beta]-cell dysfunction
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Borowiec, Maciej, Liew, Chong W., Thompson, Ryan, Boonyasrisawat, Watip, Hu, Jiang, Mlynarski, Wojciech M., Khattabi, Ilham El, Kim, Sung-Hoon, Marselli, Lorella, Rich, Stephen S., Krolewski, Andrzej S., Bonner-Weir, Susan, Sharma, Arun, Sale, Michele, Mychaleckyj, Josyf C., Kulkarni, Rohit N., and Doria, Alessandro
- Subjects
Diabetes -- Development and progression ,Diabetes -- Genetic aspects ,Pancreatic beta cells -- Genetic aspects ,Pancreatic beta cells -- Health aspects ,Science and technology - Abstract
Maturity-onset diabetes of the young (MODY) is a subtype of diabetes defined by an autosomal pattern of inheritance and a young age at onset, often before age 25. MODY is genetically heterogeneous, with 8 distinct MODY genes identified to date and more believed to exist. We resequenced 732 kb of genomic sequence at 8p23 in 6 MODY families unlinked to known MODY genes that showed evidence of linkage at that location. Of the 410 sequence differences that we identified, 5 had a frequency < 1% in the general population and segregated with diabetes in 3 of the families, including the 2 showing the strongest support for linkage at this location. The 5 mutations were all placed within 100 kb corresponding to the BLK gene. One resulted in an Ala71Thr substitution; the other 4 were noncoding and determined decreased in vitro promoter activity in reporter gene experiments. We found that BLK--a nonreceptor tyrosine-kinase of the src family of proto-oncogenes--is expressed in [beta]-cells where it enhances insulin synthesis and secretion in response to glucose by up-regulating transcription factors Pdx1 and Nkx6.1. These actions are greatly attenuated by the Ala71Thr mutation. These findings point to BLK as a previously unrecognized modulator of [beta]-cell function, the deficit of which may lead to the development of diabetes. beta cells | genetics | MODY | tyrosine kinase
- Published
- 2009
50. The Silk Vista Baby – The UK experience.
- Author
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Bhogal, P, Makalanda, HLD, Wong, K, Keston, P, Downer, J, Du Plessis, JC, Nania, A, Simonato, D, Fuschi, M, Chong, W, O'Reilly, S, and Rennie, I
- Subjects
DISSECTING aneurysms ,SILK ,ANEURYSMS ,INFANTS - Abstract
Background: The Silk Vista Baby (SVB) flow diverter (FDS) is the only FDS deliverable via a 0.017 inch microcatheter and is specifically designed for the distal vasculature. We sought to evaluate the safety and efficacy of the SVB. Materials and Methods: We performed a retrospective review to identify SVB cases at 4 tertiary neurosurgical centres within the U.K. Clinical, procedural, angiographic and follow-up data were collected. Results: We identified 60 patients (35 female, 58%) of average age 54 ± 10.5 (range 30–72) with 61 aneurysms, 50 (81.9%) located in the anterior circulation. The majority of the aneurysms treated were unruptured (46, 75.4%) and saccular (46, 75.4%). Dome size was 6.2 ± 6.2 mm (range 1–36mm) and parent vessel diameter was 2.3 ± 0.4 mm (range 1.2-3.3 mm). An average number of 1.07 devices were implanted. Coils or other devices were implanted in 14 aneurysms (23.3%). At last angiographic follow-up (n = 55), 7.5 ± 4.2 months post-procedure, 32 aneurysms (57.1%) were graded as RRC I, 7 (12.5%) RRC II, and 17 RRC III (30.4%). Clinical complications, excluding death, were seen in 4 patients (6.8%) including 1 delayed aneurysm rupture and 3 symptomatic ischaemic events. Only one patient had permanent morbidity (mRS 1). 3 patients died during follow-up (5.1%); 2 deaths were related to the aneurysms (3.4%) – one ruptured dissecting MCA aneurysm, and one giant partially thrombosed posterior circulation aneurysm. 93% of patients were mRS ≤ 2 at last follow-up. Conclusion: The SVB has high rates of technical success and an acceptable safety profile. Distal aneurysms may occlude slower due to relative oversizing of the devices. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
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