28 results on '"Chen, Kaiwen W"'
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2. The small molecule raptinal can simultaneously induce apoptosis and inhibit PANX1 activity
3. RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling
4. Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
5. Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria
6. Equally potent: Nlrp3 mutation in macrophages or neutrophils is sufficient to drive autoinflammation
7. Divide to conquer: NLRP3 is activated on dispersed trans-Golgi network
8. Inflammasome and gasdermin signaling in neutrophils
9. Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection
10. Posttranslational and Therapeutic Control of Gasdermin-Mediated Pyroptosis and Inflammation
11. Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD
12. Caspase-8–dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality
13. Beyond inflammasomes: emerging function of gasdermins during apoptosis and NETosis
14. Pannexin-1 channels bridge apoptosis to NLRP3 inflammasome activation
15. Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP 3 inflammasome assembly
16. Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria
17. Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion
18. Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity
19. XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation
20. Burn the house, save the day: pyroptosis in pathogen restriction
21. Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling
22. The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge
23. Beyond inflammasomes: emerging function of gasdermins during apoptosis and NETosis.
24. Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP3 inflammasome assembly.
25. XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation
26. Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity
27. Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
28. Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD.
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