10 results on '"Cavallino, P"'
Search Results
2. Ocular Rosacea microBiome Study (ORBS)-sub-microbial versus antibiotic dosing of doxycycline versus placebo in treatment of symptomatic ocular rosacea: study protocol for a parallel-arm randomized clinical trial.
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Mahmud, Hamidah, Keenan, Jeremy D, Gonzales, John, Schallhorn, Julie, Chan, Matilda, Arnold, Benjamin, Cavallino, Victoria, Lietman, Thomas M, Doan, Thuy, and Seitzman, Gerami D
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Humans ,Rosacea ,Doxycycline ,Anti-Infective Agents ,Anti-Bacterial Agents ,Randomized Controlled Trials as Topic ,Gastrointestinal Microbiome ,Antimicrobial resistance ,Microbiome ,Ocular rosacea ,Sub-microbial ,Prevention ,Clinical Research ,Antimicrobial Resistance ,Aging ,Eye Disease and Disorders of Vision ,Infectious Diseases ,Clinical Trials and Supportive Activities ,Evaluation of treatments and therapeutic interventions ,6.1 Pharmaceuticals ,Infection ,Good Health and Well Being ,Cardiorespiratory Medicine and Haematology ,Clinical Sciences ,Cardiovascular System & Hematology ,General & Internal Medicine - Abstract
BackgroundOcular rosacea is common and is often managed with long-term antibiotic treatment. Doxycycline is the most commonly selected antibiotic for the treatment of rosacea. As there is no established standard of care treatment dose for rosacea, prescribed doses of doxycycline vary widely. The FDA classifies 40 mg daily dose of doxycycline for ocular rosacea as sub-microbial in comparison to an antibiotic dose of 200 mg daily. However, this "sub-microbial" dose has never been evaluated in patients with ocular rosacea, and even the sub-microbial dose has potential to alter systemic mucosa flora. Here, we present a randomized controlled trial using RNA sequencing to fully characterize the impact of sub-microbial antibiotic dosing of doxycycline on antimicrobial resistance and bacterial composition of the ocular and gut flora.MethodsIn a triple-masked parallel randomized control trial, patients with ocular rosacea will be randomized to three arms: a 40-mg dose of doxycycline, a 200-mg antibiotic dose of doxycycline, or placebo. Collected rectal and lower eyelid samples will be compared for frequency of antimicrobial resistance genetic determinants and microbiome diversity. A subjective ocular surface disease index survey and objective tear breakup time measurement will be determined.DiscussionThese results will enhance our understanding of the overall systemic impact of long-term systemic sub-microbial antibiotic dosing for the treatment of chronic recurrent ocular inflammatory diseases.Trial registrationThis trial was registered on ClinicalTrials.org (NCT05296837) on March 22, 2022.
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- 2022
3. Effect of previous fighting on the dynamic of agonistic encounters in zebrafish males
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Cavallino, Luciano, Dramis, Agustín, Pedreira, María Eugenia, and Pandolfi, Matías
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- 2020
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4. Experiences of COVID-19-related anti-Asian discrimination and affective reactions in a multiple race sample of U.S. young adults
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Hahm, Hyeouk Chris, Xavier Hall, Casey D., Garcia, Kana Tsurudome, Cavallino, Anna, Ha, Yoonsook, Cozier, Yvette C., and Liu, Cindy
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- 2021
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5. Asociación entre el tratamiento hormonal y los eventos clínicos tempranos en mujeres con disección coronaria espontánea
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Mori, Ricardo, Macaya, Fernando, Giacobbe, Federico, Moreno, Víctor, Quadri, Giorgio, Chipayo, David, Bianco, Matteo, Salinas, Pablo, Rolfo, Cristina, Mejía-Rentería, Hernán, Boi, Alberto, Tirado-Conte, Gabriela, Cavallino, Chiara, Nombela-Franco, Luis, Cinconze, Sebastian, Jiménez-Quevedo, Pilar, Pavani, Marco, Fernández-Ortiz, Antonio, Chinaglia, Alessandra, Fuentes-Ferrer, Manuel Enrique, Núñez-Gil, Iván J., Gonzalo, Nieves, Cerrato, Enrico, Varbella, Ferdinando, and Escaned, Javier
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Los cambios hormonales se reconocen como un factor desencadenante de la disección coronaria espontánea (DCE). Sin embargo, se desconoce si la exposición al tratamiento con hormonas exógenas (TH) en el momento del diagnóstico tiene algún impacto clínico. Se estudió en mujeres con DCE la asociación entre la TH y los eventos clínicos a corto plazo.
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- 2023
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6. Interventional Versus Conservative Strategy in Patients With Spontaneous Coronary Artery Dissections: Insights From DISCO Registry.
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Benenati, Stefano, Giacobbe, Federico, Zingarelli, Antonio, Macaya, Fernando, Biolè, Carloalberto, Rossi, Angelica, Pavani, Marco, Quadri, Giorgio, Barbero, Umberto, Erriquez, Andrea, Aranzulla, Tiziana, Cavallino, Chiara, Buccheri, Dario, Rolfo, Cristina, Patti, Giuseppe, Gonzalo, Nieves, Chinaglia, Alessandra, Musumeci, Giuseppe, Escaned, Javier, and Varbella, Ferdinando
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Background: The optimal management of patients with spontaneous coronary artery dissection remains debated. Methods: Patients enrolled in the DISCO (Dissezioni Spontanee Coronariche) Registry up to December 2020 were included. The primary end point was major adverse cardiovascular events, a composite of all-cause death, nonfatal myocardial infarction, and repeat percutaneous coronary intervention (PCI). Independent predictors of PCI and medical management were investigated. Results: Among 369 patients, 129 (35%) underwent PCI, whereas 240 (65%) were medically managed. ST-segment–elevation myocardial infarction (68% versus 35%, P <0.001), resuscitated cardiac arrest (9% versus 3%, P <0.001), proximal coronary segment involvement (32% versus 7%, P <0.001), and Thrombolysis in Myocardial Infarction flow 0 to 1 (54% versus 20%, P <0.001) were more frequent in the PCI arm. In-hospital event rates were similar. Between patients treated with PCI and medical therapy, there were no differences in terms of major adverse cardiovascular events at 2 years (13.9% versus 11.7%, P =0.467), all-cause death (0.7% versus 0.4%, P =0.652), myocardial infarction (9.3% versus 8.3%, P =0.921) and repeat PCI (12.4% versus 8.7%, P =0.229). ST-segment–elevation myocardial infarction at presentation (odds ratio [OR], 3.30 [95% CI, 1.56–7.12]; P =0.002), proximal coronary segment involvement (OR, 5.43 [95% CI, 1.98–16.45]; P =0.002), Thrombolysis in Myocardial Infarction flow grade 0 to 1 and 2 (respectively, OR, 3.22 [95% CI, 1.08–9.96]; P =0.038; and OR, 3.98 [95% CI, 1.38–11.80]; P =0.009) and luminal narrowing (OR per 5% increase, 1.13 [95% CI, 1.01–1.28]; P =0.037) were predictors of PCI, whereas the 2B-angiographic subtype predicted medical management (OR, 0.25 [95% CI, 0.07–0.83]; P =0.026). Conclusions: Clinical presentation and procedural variables drive the choice of the initial therapeutic approach in spontaneous coronary artery dissection. If PCI is needed, it seems to be associated with a similar risk of short-to-mid-term adverse events compared to medical treatment. Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT04415762. [ABSTRACT FROM AUTHOR]
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- 2023
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7. 991 A PATIENT WITH INFERIOR Q WAVES AND CHEST PAIN: WHEN HOOF BEATS ARE NOT HORSES
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Maltese, Ludovica, Cavallino, Chiara, Ugo, Fabrizio, Abdirashid, Mohamed, and Rametta, Francesco
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- 2022
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8. 580 Percutaneous coronary intervention or medical therapy as initial management strategy of patients with spontaneous coronary artery dissections: insight from the multicentre, international dissezioni spontanee coronariche (disco) registry
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Benenati, Stefano, Giacobbe, Federico, Zingarelli, Antonio, Alessandra, Truffa Giachet, Lombardi, Primiano, Musumeci, Giuseppe, Cinconze, Sebastian, Barbero, Umberto, Iannaccone, Mario, Patti, Giuseppe, Rognoni, Antonio, Menunni, Marco, Di Leo, Angelo, Infantino, Vincenzo, Gambino, Alfonso, D’Ascenzo, Fabrizio, Bruno, Francesco, Pavani, Marco, Gagnor, Andrea, Ugo, Fabrizio, Cavallino, Chiara, Campo, Gianluca Calogero, Bettari, Luca, Cassano, Francesco, Perfetti, Matteo, Scappaticci, Massimiliano, Buccheri, Dario, Bordoni, Elisabetta, Bernelli, Chiara, Boi, Alberto, Mori, Ricardo, Macaya, Fernando, Escaned, Javier, Cerrato, Enrico, and Porto, Italo
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- 2021
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9. Ventricular fusion mimicking acute inferior myocardial infarction in a patient with a dual-chamber pacemaker.
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Bortnik, Miriam, Degiovanni, Anna, Cavallino, Chiara, and Marino, Paolo
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Abstract: Background and purpose: Early diagnosis of acute myocardial infarction is based on 12-lead electrocardiography (ECG), however this interpretation could be difficult in patients with ventricular-paced rhythm. Subject: We describe the clinical case of a 44-year-old man already implanted with a dual-chamber closed loop stimulation (CLS) pacemaker (PM) and admitted to our department with an ECG showing ST elevation in the inferior leads. All examinations were negative and showed no abnormalities. After CLS-PM was reprogrammed in order to allow the appearance of spontaneous atrioventricular conduction, we found a complete normalization of ST segment. Conclusion: After a careful analysis of admission ECG, ST elevation was interpreted as ventricular fusion due to the presence of a ventricular pacing artifact and the QRS complex being a hybrid of spontaneous and totally paced beats. Intermittent ST elevation, evident only during ventricular fusion should suggest secondary ventricular repolarization and not myocardial injury. [Copyright &y& Elsevier]
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- 2012
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10. 'Delirium Day': a nationwide point prevalence study of delirium in older hospitalized patients using an easy standardized diagnostic tool
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Bellelli, Giuseppe, Morandi, Alessandro, Di Santo, Simona G., Mazzone, Andrea, Cherubini, Antonio, Mossello, Enrico, Mario, Bo, Bianchetti, Angelo, Rozzini, Renzo, Zanetti, Ermellina, Musicco, Massimo, Ferrari, Alberto, Ferrara, Nicola, Trabucchi, Marco, Boffelli, Stefano, Stefano, Fabio Di, Filippi, Francesco De, Guerini, Fabio, Bertoletti, Erik, March, Albert, Margiotta, Alessandro, Mecocci, Patrizia, Addesi, Desireè, Fantò, Fausto, Dijik, Babette, Porrino, Paola, Cotroneo, Antonino Maria, Galli, Giovanni, Bruni, Amalia Cecilia, Bernardini, Bruno, Corsini, Carla, Cagnin, Annachiara, Zurlo, Amedeo, Barbagallo, Giuseppe, Lunardelli, Maria Lia, Martini, Emilio, Battaglia, Giuseppe, Latella, Raffaele, Petritola, Donatella, Sinforiani, Elena, Cester, Alberto, Formilan, Marino, Carbone, Pasqualina, Appollonio, Ildebrando, Cereda, Diletta, Tremolizzo, Lucio, Bottacchi, Edo, Lucchetti, Lucio, Mariani, Claudio, Rapazzini, Piero, Romanelli, Giuseppe, Marengoni, Alessandra, Zuliani, Giovanni, Bianchi, Lara, Suardi, Teresa, Muti, Ettore, Bottura, Renato, Sgrò, Giovanni, Mandas, Antonella, Serchisu, Luca, Crippa, Patrizia, Ivaldi, Claudio, Ungar, Andrea, Villani, Daniele, Raimondi, Clara, Mussi, Chiara, Isaia, Giancarlo, Provenzano, Giuseppe, Mari, Daniela, Odetti, Patrizio, Monacelli, Fiammetta, Incalzi, Raffaele Antonelli, Pluderi, Alice, Bellamoli, Claudio, Terranova, Luciano, Scarpini, Elio, D'Amico, Ferdinando, Cavallini, Maria Chiara, Guerrini, Gianbattista, Scotuzzi, Anna Maria, Chiarello, Antonino, Pilotto, Alberto, Tognini, Sara, Dell'Aquila, Giuseppina, Toigo, Gabriele, Ceschia, Giuliano, Piccinini, Maristella, Fabbo, Andrea, Zoli, Marco, Forti, Paola, Wenter, Christian, Basile, Giorgio, Lasagni, Anna, Padovani, Alessandro, Rozzini, Luca, Cottino, Maria, Vitali, Silvia, Tripi, Gabriele, Avanzi, Stefano, Annoni, Giorgio, Ruotolo, Giovanni, Boschi, Federica, Bonino, Paolo, Marchionni, Niccolo, Fascendini, Sara, Noro, Gabriele, Turco, Renato, Ubezio, Maria C., Serrati, Carlo, Infante, Maria, Gentile, Simona, Pernigotti, Luigi M., Biagini, Carlo A., Canonico, Enzo, Bonati, Pietro, Gareri, Pietro, Caffarra, Paolo, Ceretti, Arcangelo, Castiglia, Rosanna, Gabelli, Carlo, Storto, Mario Lo, Putzu, Paolo, Santo, Simona Di, Malara, Alba, Spadea, Fausto, Di Cello, Serena, Ceravolo, Francesco, Fabiano, Francesco, Rispoli, Vincenzo, Chiaradia, Giuseppe, Gabriele, Amedeo, Settembrini, Vincenzo, Capomolla, Domenico, Citrino, Antonella, Scriva, Antonietta, Bruno, Irene, Secchi, Roberto, De Martino, Eugenio, Muccinelli, Roberto, Lupi, Gerardo, Paonessa, Patrizio, Fabbri, Andrea, Castellari, Sofia, Andrea, Po, Gaggioli, Guido, Varesi, Massimo, Moneti, Paolo, Capurso, Sebastiano, Latini, Vincenzo, Ghidotti, Stefano, Riccardelli, Francesco, Macchi, Maurizio, Cassinadri, Angela, Tonini, Gabriele, Andreani, Laura, Coralli, Mirco, Balotta, Antonio, Cancelliere, Roberto, Strazzacapa, Mara, Cavallino, Pierangela, Fabio, Stefano, De Filippi, Francesco, Giudice, Chiara, Floris, Patrizia, Dentizzi, Cosimo, D’Elia, Katia, Azzini, Margherita, Cazzadori, Marco, Benati, Claudia, Tobaldini, Chiara, Antonioli, Angela, Mombelloni, Paolo, Fontanini, Fulvio, Oliverio, Martina, Del Grosso, Luciano, Giavedoni, Cristina, Bidoli, Giuliano, Mazzei, Bruno, Corsonello, Andrea, Fusco, Sergio, Vena, Silvio, De Vuono, Tommaso, Maiuri, Giorgio, Castegnaro, Eugenio, De Rosa, Salvatore, Sechi, Rossella Bazzano, Benvenuti, Enrico, Del Lungo, Ilaria, Giardini, Sante, Giulietti, Chiara, D’Amico, Ferdinando, Caronzolo, Francesco, Grippa, Alessandro, Lombardo, Giuseppina, Pipicella, Tiziana, Nitti, Maria Teresa, Felici, Alessandro, Pavan, Silvia, Piazzani, Fabrizio, Lunelli, Alessandra, Dimori, Sergio, Magnani, Angelo, Soglia, Tiziano, Postacchini, Demetrio, Brunelli, Roberto, Santini, Silvia, Francavilla, Monia, Macchiati, Ilenia, Sorvillo, Francesca, Giuli, Cinzia, Perticone, Francesco, Rosa, Paola Cerra, Bencardino, Giuseppe, Falbo, Tania, Grillo, Nadia, Isaia, Gianluca, Pezzilli, Stella, Bergamo, Daniele, Furno, Elisabetta, Rrodhe, Sokol, Lucarini, Simonetta, Dall’Acqua, Francesca, Cappelletto, Francesco, Calvani, Donatella, Becheri, Dimitri, Gambardella, Lucia, Valente, Carlo, Ceci, Giacomo, Ettorre, Evaristo, Tironi, Sara, Grassi, Maria Grazia, Troisi, Elio, Gabutto, Anna, Baglietto, Nino, Quazzo, Loredana, Rosatello, Annalisa, Suraci, Domenico, Tagliabue, Benedetta, Perrone, Chiara, Ferrara, Lucia, Castagna, Alberto, Tremolada, Maria Luisa, Piano, Simonetta, Serviddio, Gaetano, Lo Buglio, Aurelio, Gurrera, Tiziana, Merlo, Valeria, Rovai, Carla, Carlucci, Rosaria, Abbaldo, Anna, Monzani, Fabio, Qasem, Ahmad Amedeo, Bini, Giacomo, Tafuto, Silvia, Mancuso, Giovanna, Fragiacomo, Federica, Pompanin, Sara, Guerra, Gianluca, Pala, Marco, Menozzi, Luca, Gatti, Chiara Delli, Magon, Stefania, Di Francesco, Vincenzo, Faccioli, Silvia, Pellizzari, Luca, Lia Lunardelli, Maria, Macchiarulo, Maria, Corneli, Maria, Bacci, Monica, Lo Storto, Mario, Seresin, Chiara, Simonato, Matteo, Loreggian, Michele, Cestonaro, Fausta, Durando, Mario, Mazzoleni, Marta, Russo, Giuseppe, Ponte, Martino, Valchera, Alessandro, Salustri, Giuseppe, Costa, Alfredo, Cotta, Matteo Ramusino, Pizio, Renato Nicola, Perego, Germana, Bucciantini, Elisabetta, Di Giovanni, Marco, Franchi, Fabrizio, Claudio Mariani, Sara Barbieri, Grande, Giulia, Fugazza, Luciano, Guerrini, Chiara, De Paduanis, Giovanna, Iallonardo, Lucia, Palumbo, Pasquale, Ortolani, Beatrice, Capatti, Eleonora, Soavi, Cecilia, Francesconi, Daniela, Miselli, Agata, Zaccarini, Cinzia, Mirra, Gianluca, Secreto, Piero, Bisio, Erika, Cecchettani, Marco, Naldi, Tamara, Pallavicino, Alessandra, Pugliese, Michela, Iozzo, Rosaria Cosima, Guido Grassi, Giovanni Sgrò, Dell’Oro, Raffaella, Mannironi, Antonio, Giorli, Elisa, Oberti, Sara, Fierro, Brigida, Piccoli, Tommaso, Giacalone, Fabio, Costaggiu, Diego, Pinna, Elisa, Orrù, Francesca, Mannai, Martina, Cordioli, Zeno, Pelizzari, Luca, Chiloiro, Roberta, Cimino, Rosella, Ruberto, Carmen, Dal Santo, Pierluigi, Andriolli, Antonino, Burattin, Giuseppe, Rossi, Laura, Tezza, Fabiana, Aloisio, Paola, Di Monda, Tiziana, Galbassini, Gloria, Russo, Anna Maria, Pesci, Alberto, Suigo, Giulia, Zanasi, Massimo, Moniello, Giovanni, Rostagno, Carlo, Cartei, Alessandro, Polidori, Gianluca, Melis, Maria Ramona, Martellini, Eleonora, Battiston, Bruno, Berardino, Maurizio, Cavallo, Simona, Lombardi, Bruna, D’Ippolito, Pierpaolo, Furini, Angela, Guarneri, Massimo, Paolucci, Stefano, Bassi, Andrea, Coiro, Paola, De Angelis, Domenico, Morone, Giovanni, Venturiero, Vincenzo, Palleschi, Lorenzo, Raganato, Paolo, Di Niro, Giuseppina, Imoscopi, Alessandra, Tibaldi, Vittoria, Bottignole, Giuliana, Calvi, Elisa, Clementi, Carlotta, Zanocchi, Mauro, Agosta, Luca, Criasia, Antonio, Spertino, Elena, Nortarelli, Antonella, Principato, Pietro, Rizzo, Anita, Cellura, Eleonora, Zanghierato, Angelo, Romano, Federica Y., Rosini, Francesca, Mansi, Marta, Rossi, Silvia, Riccardelli, Alex, Potena, Alfredo, Lichii, Mihaela, Candiani, Tiziana, Grimaldi, William, Bertani, Emiliano, Calogero, Pietro, Pinto, Daniela, Bernardi, Roberto, Nicolino, Francesco, Galetti, Caterina, Gianstefani, Alice, Prefumo, Matteo, Paolisso, Giuseppe, Rizzo, Maria Rosaria, Prestano, Raffaele, Dalise, Anna Maria, Barra, Davide, Dal Bosco, Livio, Asprinio, Vincenzo, Dallape, Luciana, Perina, Elisa, Bartoli, Isaura Rossi, Maina, Antonella, Pecoraro, Elisabetta, Sciarra, Michela, Prudente, Angela, Benini, Lucia, Levato, Francesco, Mhiuta, Victor, Alius, Florin, Davidoaia, Diana, Giardini, Vittorio, Garancini, Mattia, Bozzini, Claudia, Tosoni, Paolo, Provoli, Emma, Cascone, Luisa, Dioli, Andrea, Ferrarin, Gianfranco, Bucci, Adelmo, Bua, Guido, Fenu, Sara, Bianchi, Giovanna, Casella, Silvia, Romano, Valentina, Belotti, Gloria, Cavaliere, Sabina, Cuni, Estella, Merciuc, Nina, Oberti, Rosella, Colombo, Katia, D’Arcangelo, Paolo, Montenegro, Nicola, Montanari, Roberto, Lamanna, Pierpaolo, Gasperini, Beatrice, Arighi, Andrea, Granata, Antonino, Ranalli, Claudia, Cammilli, Alessandra, Tricca, Manola, Natella, Daniela, Sozzi, Ferdinando, Valenti, Luigi, Monia, Monella, Prete, Camilla, Senesi, Barbara, Meta, Anna Cristina, Pendenza, Enrico, Pasqualetti, Giuseppe, Polini, Antonio, Ballino, Elena, Dell’Aquila, Giuseppina, Gasparrini, Pina Maria, Marotti, Elisabetta, Migale, Monica, Scrimieri, Antonia, Rosso, Alessia, Tongiorgi, Chiara, Scarpa, Cristina, Pacchioni, Maurizio, De Dominicis, Luigino, Pucci, Eugenio, Renzi, Sara, Cartechini, Elisabetta, Barilaro, Giuseppe, Ugenti, Francesca, Romeo, Pasquale, Nardelli, Anna, Lauretani, Fulvio, Visioli, Sandra, Montanari, Ilaria, Ermini, Francesca, Giordano, Antonio, Pigato, Giorgio, Simeone, Emilio, Colameco, Franco, Cecamore, Antonella, Scurti, Rosa, Lupinetti, Maria Cristina, Barbujani, Mario, Perazzi, Beatrice, Giampieri, Marina, Amoruso, Raffaele, Ferrari, Camilla, Gambetti, Claudio, Sfrappini, Mario, Semeraro, Letizia, Striuli, Rinaldo, Mariani, Claudia, Pelliccioni, Giuseppe, Marinelli, Donatella, Rossi, Tommaso, Pesallaccia, Martina, Sabbatini, Debora, Gobbi, Beatrice, Cerqua, Raffaella, Tagliani, Giancarla, Schlauser, Elena, Caser, Luciano, Caramello, Elisa, Sandigliano, Franca, Rosso, Giorgio, Bendini, Chiara, Scevola, Moreno, Vitale, Enrico, Maugeri, Domenico, Sorace, Rosaria, Anzaldi, Massimiliano, De Gesu, Roberto, Morrone, Giuseppe, Davolio, Federica, Pirazzoli, Luca, Fabbri, Elisa, Ruffini, Ingrid, Insam, Miriam, Abraham, Elisabeth, Kirchlechner, Christine, Cucinotta, Domenico, Parise, Pasquale, Boccali, Andrea, Amici, Serena, Gambacorta, Maurizia, Lovati, Roberto, Giovinazzo, Francesca, Kimak, Elzbieta, Lo Castro, Marika, Mauro, Flavia, De Luca, Alessandro, Sancesario, Giuseppe, Martorana, Alessandro, Scaricamazza, Beatrice, Toniolo, Sofia, Di Lorenzo, Francesco, Liguori, Claudio, Lasco, Antonino, Vita, Natale, Giomi, Mirna, Forte, Floriana, Ceraso, Anna, Marelli, Eleonora, Miceli, Salvatore, Urso, Giovanni, Grioni, Giuseppe, Vezzadini, Giuliana, Misaggi, Giulia, Forlani, Chiara, Iemolo, Francesco, Giordano, Antonello, Sanzaro, Enzo, D’Asta, Gabriele, Proietto, Maria, Carnemolla, Anna, Razza, Grazia, Spadaro, Daniela, Bertolotti, Marco, Neviani, Francesca, Balestri, Francesca, Torrini, Monica, Mannarino, Giulio, Tesi, Francesca, Bigolari, Michela, Natale, Alessia, Grassi, Simona, Bottaro, Cinzia, Stefanelli, Sara, Bovone, Ugo, Tortorolo, Umberto, Quadri, Roberto, Leone, Giuseppe, Ponzetto, Maria, Frasson, Paola, Bruni, Adriana, Confalonieri, Roberto, Corsi, Maurizio, Moretti, Daniela, Teruzzi, Fabiola, Umidi, Simona, Barocco, Federica, Spallazzi, Marco, Chioatto, Paolo, Bortolamei, Sandra, Soattin, Lucia, Bertazzoli, Marco, Rota, Elisabetta, Adobati, Annamaria, Scarpa, Alberto, Granziera, Serena, Zuccher, Paola, Dal Fabbro, Angela, Zara, Daniela, Lo Nigro, Ambra, Franchetti, Lorena, Toniolo, Marika, Marcuzzo, Cinzia, Rollone, Marco, Guerriero, Fabio, Sgarlata, Carmelo, Massè, Alessandro, Zatti, Giovanni, Piatti, Massimiliano, Graci, Jole, Benati, Giuseppe, Biondi, Mario, Fiumi, Nicoletta, Locatelli, Sergio M., Mauri, Sabrina, Beretta, Mauro, Margheritis, Laura, Desideri, Giovanbattista, Liberatore, Ester, Carucci, Anna Cecilia, Caput, Margherita, Antonietti, Maria Paola, Polistena, Giuseppe, De la Pierre, Franz, Mari, Marcello, Massignani, Paola, Tombesi, Fabio, Selvaggio, Fabio, Verbo, Brunella, Bodoni, Paolo, Marchionni, Niccolò, Sabatini, Tony, Mussio, Eleonora, Titoldini, Giulia, Cossu, Beatrice, Licini, Cristina, Tomasoni, Angela, Calderazzo, Massimo, Prampolini, Raffaella, Melotti, Rita Maria, Lilli, Albina, Buda, Simona, Adversi, Marco, Mantovani, Anna Roberta, Viola, Maria C., D’Ambrosio, Viviana, Mazzanti, Paolo, Brambilla, Cristina, Sportelli, Silvia, Quattrocchi, Daniela, Pisu, Cristina, Sicuro, Francesca, Zagnoni, Piergiuseppe, Ghiglia, Stefania, Mosca, Massimiliano, Corazzin, Ileana, Deola, Mariangela, Biagini, Carlo Adriano, Bencini, Francesca, Cantini, Claudia, Tonon, Elisabetta, Pierinelli, Silvia, Onofrj, Marco, Thomas, Astrid, Bonanni, Laura, Cacchiò, Gabriella, Comi, Giancarlo, Magnani, Giuseppe, Santangelo, Roberto, Mazzeo, Salvatore, Barbieri, Cristina, Giroldi, Liviana, Bandini, Fabio, Masina, Marco, Malservisi, Simona, Cicognani, Annalena, Ricca, Laura, Tassinari, Tiziana, Brogi, Davide, Sugo, Annalisa, Bellelli G., Morandi A., Di Santo S.G., Mazzone A., Cherubini A., Mossello E., Bo M., Bianchetti A., Rozzini R., Zanetti E., Musicco M., Ferrari A., Ferrara N., Trabucchi M., Boffelli S., Stefano F.D., Filippi F.D., Guerini F., Bertoletti E., March A., Margiotta A., Mecocci P., Addesi D., Fanto F., Dijik B., Porrino P., Cotroneo A.M., Galli G., Bruni A.C., Bernardini B., Corsini C., Cagnin A., Zurlo A., Barbagallo G., Lunardelli M.L., Martini E., Battaglia G., Latella R., Petritola D., Sinforiani E., Cester A., Formilan M., Carbone P., Appollonio I., Cereda D., Tremolizzo L., Bottacchi E., Lucchetti L., Mariani C., Rapazzini P., Romanelli G., Marengoni A., Zuliani G., Bianchi L., Suardi T., Muti E., Bottura R., Sgro G., Mandas A., Serchisu L., Crippa P., Ivaldi C., Ungar A., Villani D., Raimondi C., Mussi C., Isaia G., Provenzano G., Mari D., Odetti P., Monacelli F., Incalzi R.A., Pluderi A., Bellamoli C., Terranova L., Scarpini E., D'Amico G., Cavallini M.C., Guerrini G., Scotuzzi A.M., Chiarello A., Pilotto A., Tognini S., Dell'Aquila G., Toigo G., Ceschia G., Piccinini M., Fabbo A., Zoli M., Forti P., Wenter C., Basile G., Lasagni A., Padovani A., Rozzini L., Cottino M., Vitali S., Tripi G., Avanzi S., Annoni G., Ruotolo G., Boschi F., Bonino P., Marchionni N., Fascendini S., Noro G., Turco R., Ubezio M.C., Serrati C., Infante M., Gentile S., Pernigotti L.M., Biagini C.A., Canonico E., Bonati P., Gareri P., Caffarra P., Ceretti A., Castiglia R., Gabelli C., Storto M.L., Putzu P., Santo S.D., Malara A., Spadea F., Di Cello S., Ceravolo F., Fabiano F., Rispoli V., Chiaradia G., Gabriele A., Settembrini V., Capomolla D., Citrino A., Scriva A., Bruno I., Secchi R., De Martino E., Muccinelli R., Lupi G., Paonessa P., Fabbri A., Castellari S., Po A., Gaggioli G., Varesi M., Moneti P., Capurso S., Latini V., Ghidotti S., Riccardelli F., Macchi M., Cassinadri A., Tonini G., Andreani L., Coralli M., Balotta A., Cancelliere R., Strazzacapa M., Cavallino P., Fabio S., De Filippi F., Giudice C., Floris P., Dentizzi C., D'Elia K., Azzini M., Cazzadori M., Benati C., Tobaldini C., Antonioli A., Mombelloni P., Fontanini F., Oliverio M., Del Grosso L., Giavedoni C., Bidoli G., Mazzei B., Corsonello A., Fusco S., Vena S., De Vuono T., Maiuri G., Castegnaro E., De Rosa S., Sechi R.B., Benvenuti E., Del Lungo I., Giardini S., Giulietti C., D'Amico F., Caronzolo F., Grippa A., Lombardo G., Pipicella T., Nitti M.T., Felici A., Pavan S., Lunelli A., Dimori S., Magnani A., Soglia T., Postacchini D., Brunelli R., Santini S., Francavilla M., Macchiati I., Sorvillo F., Giuli C., Perticone F., Rosa P.C., Bencardino G., Falbo T., Grillo N., Pezzilli S., Bergamo D., Furno E., Rrodhe S., Lucarini S., Dall'Acqua F., Cappelletto F., Calvani D., Becheri D., Gambardella L., Valente C., Ceci G., Ettorre E., Tironi S., Grassi M.G., Troisi E., Gabutto A., Baglietto N., Quazzo L., Rosatello A., Suraci D., Tagliabue B., Perrone C., Ferrara L., Castagna A., Tremolada M., Piano S., Serviddio G., Lo Buglio A., Gurrera T., Merlo V., Rovai C., Carlucci R., Abbaldo A., Monzani F., Qasem A., Bini G., Tafuto S., Mancuso G., Fragiacomo F., Pompanin S., Guerra G., Pala M., Menozzi L., Gatti C.D., Magon S., Di Francesco V., Faccioli S., Pellizzari L., Lia Lunardelli M., Macchiarulo M., Corneli M., Bacci M., Lo Storto M., Seresin C., Simonato M., Loreggian M., Cestonaro F., Durando M., Mazzoleni M., Russo G., Ponte M., Valchera A., Salustri G., Costa A., Cotta M.R., Pizio R.N., Perego G., Bucciantini E., Di Giovanni M., Franchi F., Claudio Mariani S.B., Grande G., Fugazza L., Guerrini C., De Paduanis G., Iallonardo L., Palumbo P., Ortolani B., Capatti E., Soavi C., Francesconi D., Miselli A., Zaccarini C., Mirra G., Secreto P., Bisio E., Cecchettani M., Naldi T., Pallavicino A., Pugliese M., Iozzo R., Guido Grassi G.S., Dell'Oro R., Mannironi A., Giorli E., Oberti S., Fierro B., Piccoli T., Giacalone F., Costaggiu D., Pinna E., Orru F., Mannai M., Cordioli Z., Pelizzari L., Chiloiro R., Cimino R., Ruberto C., Dal Santo P., Andriolli A., Burattin G., Rossi L., Tezza F., Aloisio P., Di Monda T., Galbassini G., Russo A., Pesci A., Suigo G., Zanasi M., Moniello G., Rostagno C., Cartei A., Polidori G., Melis M., Martellini E., Battiston B., Berardino M., Cavallo S., Lombardi B., D'Ippolito P., Furini A., Guarneri M., Paolucci S., Bassi A., Coiro P., De Angelis D., Morone G., Venturiero V., Palleschi L., Raganato P., Di Niro G., Imoscopi A., Tibaldi V., Bottignole G., Calvi E., Clementi C., Zanocchi M., Agosta L., Criasia A., Spertino E., Nortarelli A., Principato P., Rizzo A., Cellura E., Zanghierato A., Romano F.Y., Rosini F., Mansi M., Rossi S., Riccardelli A., Potena A., Lichii M., Candiani T., Grimaldi W., Bertani E., Calogero P., Pinto D., Bernardi R., Nicolino F., Galetti C., Gianstefani A., Prefumo M., Paolisso G., Rizzo M.R., Prestano R., Dalise A.M., Barra D., Dal Bosco L., Asprinio V., Dallape L., Perina E., Bartoli I.R., Maina A., Pecoraro E., Sciarra M., Prudente A., Benini L., Levato F., Mhiuta V., Alius F., Davidoaia D., Giardini V., Garancini M., Bozzini C., Tosoni P., Provoli E., Cascone L., Dioli A., Ferrarin G., Bucci A., Bua G., Fenu S., Bianchi G., Casella S., Romano V., Belotti G., Cavaliere S., Cuni E., Merciuc N., Oberti R., Colombo K., D'Arcangelo P., Montenegro N., Montanari R., Lamanna P., Gasperini B., Arighi A., Granata A., Ranalli C., Cammilli A., Tricca M., Natella D., Sozzi F., Valenti L., Monia M., Prete C., Senesi B., Meta A.C., Pendenza E., Pasqualetti G., Polini A., Ballino E., Gasparrini P., Marotti E., Migale M., Scrimieri A., Rosso A., Tongiorgi C., Scarpa C., Pacchioni M., De Dominicis L., Pucci E., Renzi S., Cartechini E., Barilaro G., Ugenti F., Romeo P., Nardelli A., Lauretani F., Visioli S., Montanari I., Ermini F., Giordano A., Pigato G., Simeone E., Colameco F., Cecamore A., Scurti R., Lupinetti M.C., Barbujani M., Perazzi B., Giampieri M., Amoruso R., Ferrari C., Gambetti C., Sfrappini M., Semeraro L., Striuli R., Pelliccioni G., Marinelli D., Rossi T., Pesallaccia M., Sabbatini D., Gobbi B., Cerqua R., Tagliani G., Schlauser E., Caser L., Caramello E., Sandigliano F., Rosso G., Bendini C., Scevola M., Vitale E., Maugeri D., Sorace R., Anzaldi M., De Gesu R., Morrone G., Davolio F., Pirazzoli L., Fabbri E., Ruffini I., Insam M., Abraham E., Kirchlechner C., Cucinotta D., Parise P., Boccali A., Amici S., Gambacorta M., Lovati R., Giovinazzo F., Kimak E., Lo Castro M., Mauro F., De Luca A., Sancesario G., Martorana A., Scaricamazza B., Toniolo S., Di Lorenzo F., Liguori C., Lasco A., Vita N., Giomi M., Forte F., Ceraso A., Marelli E., Miceli S., Urso G., Grioni G., Vezzadini G., Misaggi G., Forlani C., Iemolo F., Sanzaro E., D'Asta G., Proietto M., Carnemolla A., Razza G., Spadaro D., Bertolotti M., Neviani F., Balestri F., Torrini M., Mannarino G., Tesi F., Bigolari M., Natale A., Grassi S., Bottaro C., Stefanelli S., Bovone U., Tortorolo U., Quadri R., Leone G., Ponzetto M., Frasson P., Bruni A., Confalonieri R., Corsi M., Moretti D., Teruzzi F., Umidi S., Barocco F., Spallazzi M., Chioatto P., Bortolamei S., Soattin L., Bertazzoli M., Rota E., Adobati A., Scarpa A., Granziera S., Zuccher P., Dal Fabbro A., Zara D., Lo Nigro A., Franchetti L., Toniolo M., Marcuzzo C., Rollone M., Guerriero F., Sgarlata C., Masse A., Zatti G., Piatti M., Graci J., Benati G., Biondi M., Fiumi N., Locatelli S.M., Mauri S., Beretta M., Margheritis L., Desideri G., Liberatore E., Carucci A.C., Caput M., Antonietti M.P., Polistena G., De la Pierre F., Mari M., Massignani P., Tombesi F., Selvaggio F., Verbo B., Bodoni P., Sabatini T., Mussio E., Titoldini G., Cossu B., Licini C., Tomasoni A., Calderazzo M., Prampolini R., Melotti R.M., Lilli A., Buda S., Adversi M., Mantovani A.R., Viola M.C., D'Ambrosio V.V., Mazzanti P., Brambilla C., Sportelli S., Quattrocchi D., Pisu C., Sicuro F., Zagnoni P., Ghiglia S., Mosca M., Corazzin I., Deola M., Bencini F., Cantini C., Tonon E., Pierinelli S., Onofrj M., Thomas A., Bonanni L., Cacchio G., Comi G., Magnani G., Santangelo R., Mazzeo S., Barbieri C., Giroldi L., Bandini F., Masina M., Malservisi S., Cicognani A., Ricca L., Tassinari T., Brogi D., Sugo A., Bellelli, G, Morandi, A, Di Santo, S, Mazzone, A, Cherubini, A, Mossello, E, Bo, M, Bianchetti, A, Rozzini, R, Zanetti, E, Musicco, M, Ferrari, A, Ferrara, N, Trabucchi, M, Appollonio, I, Cereda, D, Tremolizzo, L, Annoni, G, Zatti, G, Bellelli, Giuseppe, Morandi, Alessandro, Di Santo, Simona G, Mazzone, Andrea, Cherubini, Antonio, Mossello, Enrico, Bo, Mario, Bianchetti, Angelo, Rozzini, Renzo, Zanetti, Ermellina, Musicco, Massimo, Ferrari, Alberto, Ferrara, Nicola, Trabucchi, Marco, Giuseppe Bellelli, Alessandro Morandi, Simona G. Di Santo, Andrea Mazzone, Antonio Cherubini, Enrico Mossello, Mario Bo, Angelo Bianchetti, Renzo Rozzini, Ermellina Zanetti, Massimo Musicco, Alberto Ferrari, Nicola Ferrara, Marco Trabucchi, and on behalf of the Italian Study Group on Delirium (ISGoD), Stefano Boffelli, Fabio Di Stefano, Francesco De Filippi, Fabio Guerini, Erik Bertoletti, Albert March, Alessandro Margiotta, Patrizia Mecocci, Desireè Addesi, Fausto Fantò, Gianluca Isaia, Babette Dijik, Paola Porrino, Antonino Maria Cotroneo, Giovanni Galli, Amalia Cecilia Bruni, Bruno Bernardini, Carla Corsini, Annachiara Cagnin, Amedeo Zurlo, Giuseppe Barbagallo, Maria Lia Lunardelli, Emilio Martini, Giuseppe Battaglia, Raffaele Latella, Donatella Petritola, Elena Sinforiani, Alberto Cester, Marino Formilan, Pasqualina Carbone, Ildebrando Appollonio, Diletta Cereda, Lucio Tremolizzo, Edo Bottacchi, Lucio Lucchetti, Claudio Mariani, Piero Rapazzini, Giuseppe Romanelli, Alessandra Marengoni, Giovanni Zuliani, Lara Bianchi, Teresa Suardi, Ettore Muti, Renato Bottura, Giovanni Sgrò, Antonella Manda, Luca Serchisu, Patrizia Crippa, Claudio Ivaldi, Andrea Ungar, Daniele Villani, Clara Raimondi, Chiara Mussi, Giancarlo Isaia, Giuseppe Provenzano, Daniela Mari, Patrizio Odetti, Fiammetta Monacelli, Raffaele Antonelli Incalzi, Alice Pluderi, Claudio Bellamoli, Luciano Terranova, Elio Scarpini, Ferdinando D'Amico, Maria Chiara Cavallini, Gianbattista Guerrini, Anna Maria Scotuzzi, Antonino Chiarello, Alberto Pilotto, Sara Tognini, Giuseppina Dell’Aquila, Gabriele Toigo, Giuliano Ceschia, Maristella Piccinini, Andrea Fabbo, Marco Zoli, Paola Forti, Christian Wenter, Giorgio Basile, Anna Lasagni, Alessandro Padovani, Luca Rozzini, Maria Cottino, Silvia Vitali, Gabriele Tripi, Stefano Avanzi, Giorgio Annoni, Giovanni Ruotolo, Federica Boschi, Paolo Bonino, Niccolò Marchionni, Maria C. Cavallini, Sara Fascendini, Gabriele Noro, Renato Turco, Maria C. Ubezio, Carlo Serrati, Maria Infante, Simona Gentile, Luigi M. Pernigotti, Carlo A. Biagini, Enzo Canonico, Pietro Bonati, Pietro Gareri, Paolo Caffarra, Arcangelo Ceretti, Rosanna Castiglia, Carlo Gabelli, Mario Lo Storto, Paolo Putzu, Simona Di Santo, Andrea, Mazzone, and Rita Maria Melotti
- Subjects
Male ,Cross-sectional study ,Hospitalized patients ,Prevalence ,0302 clinical medicine ,Surveys and Questionnaires ,80 and over ,Odds Ratio ,Medicine ,030212 general & internal medicine ,Prospective Studies ,Prospective cohort study ,Multicenter ,Acute hospital ,2. Zero hunger ,Aged, 80 and over ,Medicine(all) ,Medicine (all) ,Settore BIO/14 ,General Medicine ,3. Good health ,4AT ,Delirium ,Hospital ,Aged ,Cross-Sectional Studies ,Female ,Humans ,Inpatients ,Italy ,Logistic Models ,medicine.symptom ,Research Article ,Rehabilitation hospital ,medicine.medical_specialty ,NO ,03 medical and health sciences ,4AT, Delirium, Hospital, Multicenter, Prevalence, Aged, Aged, 80 and over, Cross-Sectional Studies, Delirium, Female, Humans, Inpatients, Italy, Logistic Models, Male, Odds Ratio, Prevalence, Prospective Studies, Surveys and Questionnaires ,mental disorders ,Psychiatry ,business.industry ,Odds ratio ,Emergency medicine ,business ,030217 neurology & neurosurgery - Abstract
Background To date, delirium prevalence in adult acute hospital populations has been estimated generally from pooled findings of single-center studies and/or among specific patient populations. Furthermore, the number of participants in these studies has not exceeded a few hundred. To overcome these limitations, we have determined, in a multicenter study, the prevalence of delirium over a single day among a large population of patients admitted to acute and rehabilitation hospital wards in Italy. Methods This is a point prevalence study (called “Delirium Day”) including 1867 older patients (aged 65 years or more) across 108 acute and 12 rehabilitation wards in Italian hospitals. Delirium was assessed on the same day in all patients using the 4AT, a validated and briefly administered tool which does not require training. We also collected data regarding motoric subtypes of delirium, functional and nutritional status, dementia, comorbidity, medications, feeding tubes, peripheral venous and urinary catheters, and physical restraints. Results The mean sample age was 82.0 ± 7.5 years (58 % female). Overall, 429 patients (22.9 %) had delirium. Hypoactive was the commonest subtype (132/344 patients, 38.5 %), followed by mixed, hyperactive, and nonmotoric delirium. The prevalence was highest in Neurology (28.5 %) and Geriatrics (24.7 %), lowest in Rehabilitation (14.0 %), and intermediate in Orthopedic (20.6 %) and Internal Medicine wards (21.4 %). In a multivariable logistic regression, age (odds ratio [OR] 1.03, 95 % confidence interval [CI] 1.01–1.05), Activities of Daily Living dependence (OR 1.19, 95 % CI 1.12–1.27), dementia (OR 3.25, 95 % CI 2.41–4.38), malnutrition (OR 2.01, 95 % CI 1.29–3.14), and use of antipsychotics (OR 2.03, 95 % CI 1.45–2.82), feeding tubes (OR 2.51, 95 % CI 1.11–5.66), peripheral venous catheters (OR 1.41, 95 % CI 1.06–1.87), urinary catheters (OR 1.73, 95 % CI 1.30–2.29), and physical restraints (OR 1.84, 95 % CI 1.40–2.40) were associated with delirium. Admission to Neurology wards was also associated with delirium (OR 2.00, 95 % CI 1.29–3.14), while admission to other settings was not. Conclusions Delirium occurred in more than one out of five patients in acute and rehabilitation hospital wards. Prevalence was highest in Neurology and lowest in Rehabilitation divisions. The “Delirium Day” project might become a useful method to assess delirium across hospital settings and a benchmarking platform for future surveys. Electronic supplementary material The online version of this article (doi:10.1186/s12916-016-0649-8) contains supplementary material, which is available to authorized users.
- Published
- 2016
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