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2. Altieri modified Nesbit corporoplasty for the treatment of penile curvature: Comparison of local anesthesia vs loco-regional anesthesia on the clinical outcomes.

Author

Altieri, Vincenzo Maria, Saldutto, Pietro, Verratti, Vittore, La Rocca, Roberto, Di Mauro, Ernesto, Celentano, Giuseppe, Capece, Marco, Morgera, Vincenzo, Cacace, Gianluigi, Vena, Walter, Mastrangelo, Francesco, Napolitano, Luigi, and Iacono, Fabrizio

Subjects
SPINAL anesthesia, PENILE induration, POSTOPERATIVE pain, PENIS curvatures, SURGICAL complications, LOCAL anesthesia, CONDUCTION anesthesia
Abstract

Objective: To compare the safety profile and clinical outcomes of Altieri-modified Nesbit corporoplasty using two different anesthesia methods including spinal anesthesia and local anesthesia. Materials and methods: A total of 40 patients with congenital penile curvature (CPC) and Peyronie's disease (PD) underwent Altieri-modified Nesbit corporoplasty. Group 1 (n = 20) received spinal anesthesia, and Group 2 (n = 20) received local anesthesia. The patients were categorized into age groups (< 30 years, 31-45 years, 46-60 years, and 61-75 years) for analysis. Clinical outcomes, post-operative complications, hospital stay, pain levels, and other parameters were assessed. Results: The results showed that 2 patients (10%) reported postoperative complications, including headache, arterial hypotension, and penile foreskin necrosis from the spinal anesthesia group. Whereas, in the local anesthesia group, 1 patient (5%) reported scar phimosis. Further, post-operative pain was predominantly very mild, with 16 patients (80%) in the spinal anesthesia group and 14 patients (70%) in the local anesthesia group experiencing minimal discomfort. Age did not significantly impact hospital stay, post-operative intestinal disorders, constipation, lower urinary tract symptoms, voiding burning, or dysuria. Conclusions: Spinal anesthesia may lead to more post-operative complications and longer hospital stays compared to local anesthesia. Age does not significantly affect most clinical outcomes but can influence post-operative pain in patients receiving local anesthesia. [ABSTRACT FROM AUTHOR]

Published
2024
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3. Telemedicine and social media: A contemporary analysis of the most shared content by internet users

Author

Mirone, Vincenzo, primary, Di Bello, Francesco, additional, Morra, Simone, additional, Califano, Gianluigi, additional, Cirillo, Luigi, additional, Abate, Marco, additional, Fusco, Giovanni Maria, additional, Luzzago, Stefano, additional, Mirone, Claudia, additional, Napolitano, Luigi, additional, La Rocca, Roberto, additional, Creta, Massimiliano, additional, Celentano, Giuseppe, additional, Capece, Marco, additional, Musi, Gennaro, additional, Mangiapia, Francesco, additional, Longo, Nicola, additional, and Collà Ruvolo, Claudia, additional

Published
2024
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4. Risk and benefits of penile length preservation techniques during penile prosthesis implantation: a systematic review by the young academic urologists sexual and reproductive health working group

Author

Falcone, Marco, primary, Preto, Mirko, additional, Morgado, Afonso Ribeiro, additional, Sokolakis, Ioannis, additional, Sarıkaya, Selçuk, additional, Capece, Marco, additional, Capogrosso, Paolo, additional, Manfredi, Celeste, additional, Tsampoukas, Georgios, additional, and Russo, Giorgio, additional

Published
2024
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9. Demographics, Clinical Characteristics and Survival Outcomes of Primary Urinary Tract Malignant Melanoma Patients: A Population-Based Analysis

Author

Morra, Simone, primary, Incesu, Reha-Baris, additional, Scheipner, Lukas, additional, Baudo, Andrea, additional, Jannello, Letizia Maria Ippolita, additional, de Angelis, Mario, additional, Siech, Carolin, additional, Goyal, Jordan A., additional, Tian, Zhe, additional, Saad, Fred, additional, Califano, Gianluigi, additional, la Rocca, Roberto, additional, Capece, Marco, additional, Shariat, Shahrokh F., additional, Ahyai, Sascha, additional, Carmignani, Luca, additional, de Cobelli, Ottavio, additional, Musi, Gennaro, additional, Tilki, Derya, additional, Briganti, Alberto, additional, Chun, Felix K. H., additional, Longo, Nicola, additional, and Karakiewicz, Pierre I., additional

Published
2023
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10. Effects of long and short ejaculatory abstinence on sperm parameters: a meta-analysis of randomized-controlled trials.

Author

Lo Giudice, Arturo, Asmundo, Maria Giovanna, Cimino, Sebastiano, Cocci, Andrea, Falcone, Marco, Capece, Marco, Abdelhameed, Ali Saber, Capogrosso, Paolo, Morgado, Afonso, Tsampoukas, Georgios, Manfredi, Celeste, and Russo, Giorgio Ivan

Subjects
SEXUAL abstinence, SPERMATOZOA, SEMEN, SPERM motility
Abstract

Purpose: This study aimed to investigate the effects of ejaculatory abstinence on sperm parameters. Methods: This analysis was registered in PROSPERO (CRD42023472124). We performed a search on PubMed using the following text terms: (("sperm parameters" OR "sperm analysis" [Mesh]) AND ("sperm DNA fragmentation" OR "DNA fragmentation" [Mesh]) AND ("sexual abstinence" [Mesh] OR "abstinence")) and an advanced search in Scopus using the terms ("sperm parameters" OR "sperm parameters" OR "DNA fragmentation") AND ("abstinence"). The sperm parameters that were investigated were sperm volume, total sperm motility, progressive sperm motility, sperm concentration, sperm morphology, and sperm DNA fragmentation (SDF). A two-day cut-off as a "short" or "long" abstinence period has been defined. Results: Thirteen studies published between 2013 and 2022 were included in this meta-analysis. A total of 2,315 patients, ranging from 6 to 836 from each cohort, were enrolled in the study. We showed that longer abstinence time was associated with greater sperm concentration (mean difference [MD]: 8.19; p <0.01), sperm volume (MD: 0.96; p <0.01), and higher SDF (MD: 3.46; p <0.01), but lower progressive sperm motility (MD: -1.83; p <0.01). Otherwise, no statistically significant difference was observed in patients with longer vs. shorter abstinence times regarding total sperm motility (MD: -1.83; p = 0.06). Meta-regression analysis showed that days of abstinence were positively and linearly related to sperm concentration (slope: 3.74; p <0.01) and SDF (slope: 0.65; p = 0.044). Conclusions: According to our data, short ejaculatory abstinence is associated with better sperm quality. Indeed, a higher percentage of progressive sperm motility and lower levels of SDF have been reported in a short abstinence cohort. In contrast, the long abstinence group reported a higher sperm concentration. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Intraplaque injections of hyaluronic acid for the treatment of stable-phase Peyronie's disease: a retrospective single-center experience.

Author

Cilio, Simone, La Rocca, Roberto, Celentano, Giuseppe, Marino, Claudio, Creta, Massimiliano, Califano, Gianluigi, Manfredi, Celeste, Russo, Giorgio Ivan, Morgado, Afonso, Falcone, Marco, and Capece, Marco

Abstract

Peyronie's disease (PD) is a condition of penile connective tissue affecting up to 10% of men worldwide. In the complexity of its management, nonsurgical treatments, such as intraplaque injections, are gaining attention. The current literature shows data on the efficacy of intraplaque injections of hyaluronic acid (HA) mainly in acute-phase PD. However, data on injections of HA in stable-phase PD are lacking. Data for this retrospective study were derived from a prospectively maintained database of private patients presenting at a private medical practice affiliated to the University of Naples "Federico II" (Naples, Italy) with stable-phase PD between January 2020 and March 2023. Patients underwent a standard protocol of three injections, each administered at a two-week interval. During the intervals, patients performed vacuum device therapy, penile stretching, and modeling exercises. All patients compiled the Peyronie's Disease Questionnaire (PDQ) and Global Assessment of Peyronie's Disease (GAPD) at baseline and 2 weeks after the third injection. A penile Doppler ultrasound was performed 2 weeks after the last injection to record the final curvature. Overall, we recruited 62 patients with stable-phase PD and a mean (±standard deviation [s.d.]) curvature of 52.7° (±9.7°). After 6 weeks, eight (12.9%) patients did not experience any curvature improvement. The remaining 54 patients had a final mean (±s.d.) curvature of 40.3° (±9.1°) with P < 0.001, compared to that before treatment. We found improvement in all PDQ domains (all P = 0.01), and 50 (80.6%) patients reported subjective improvement of the penile curvature according to the GAPD. In conclusion, we demonstrated that after three injections of HA administered according to the adopted protocol, patients with stable-phase PD could experience significant improvements in penile curvature, and physical and psychological consequences of the disease without significantly relevant side effects. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Telemedicine and YouTube™: Video quality analysis before and after COVID-19 pandemic

Author

Mirone, Vincenzo, primary, Abate, Marco, additional, Fusco, Giovanni Maria, additional, Cirillo, Luigi, additional, Napolitano, Luigi, additional, Morra, Simone, additional, Di Bello, Francesco, additional, Califano, Gianluigi, additional, Mirone, Claudia, additional, La Rocca, Roberto, additional, Creta, Massimiliano, additional, Celentano, Giuseppe, additional, Capece, Marco, additional, Mangiapia, Francesco, additional, Longo, Nicola, additional, and Collà Ruvolo, Claudia, additional

Published
2023
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13. Two-Stage Penile Reconstruction after Paraffin Injection: A Case Report and a Systematic Review of the Literature

Author

Napolitano, Luigi, primary, Marino, Claudio, additional, Di Giovanni, Angelo, additional, Zimarra, Assunta, additional, Giordano, Alessandro, additional, D’Alterio, Carlo, additional, Califano, Gianluigi, additional, Creta, Massimiliano, additional, Celentano, Giuseppe, additional, La Rocca, Roberto, additional, Mirone, Claudia, additional, Spena, Gianluca, additional, Palmieri, Alessandro, additional, Longo, Nicola, additional, Imbimbo, Ciro, additional, and Capece, Marco, additional

Published
2023
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14. Penile Prosthesis Implantation in Refractory Ischaemic Priapism: Patient Selection and Special Considerations

Author

Capece, Marco, Falcone, Marco, Cai, Tommaso, Palmieri, Alessandro, Cocci, Andrea, La Rocca, Roberto, Capece, M., Falcone, M., Cai, T., Palmieri, A., Cocci, A., and La Rocca, R.

Subjects
erectile dysfunction, priapism, penile prosthesis, Urology, refractory ischemic priapism, RC870-923, Review, urologic and male genital diseases, Diseases of the genitourinary system. Urology, Penile prosthesi
Abstract

Marco Capece,1 Marco Falcone,2 Tommaso Cai,3 Alessandro Palmieri,1 Andrea Cocci,4 Roberto La Rocca1 1Department of Urology, AOU Federico II, University Hospital, Naples, Italy; 2Department of Neurourology, A.O.U. Città della Salute e della Scienza di Torino - Unità Spinale Unipolare, Turin, Italy; 3Ospedale Santa Chiara, Trento, Italy; 4Department of Oncologic, Minimally-Invasive Urology and Andrology, Careggi Hospital, University of Florence, Florence, ItalyCorrespondence: Alessandro PalmieriDepartment of Neuroscience, Reproductive Science and Odontostomatology, University Federico II of Naples, via S.Pansini 5, Naples, 80131, ItalyTel +39 081 746 2611Fax +39 081 746 4311Email androfedii@gmail.comAbstract: Ischemic priapism accounts for more than 95% of all priapic episodes. It has to be considered a urological emergency because its time extension may lead to necrosis of smooth muscle cells of the corpora cavernosa, resulting in a complete erectile dysfunction, penile shortening and loss of girth. In the present systematic review, we perform an up-to-date literature search for patients suffering from refractory ischemic priapism who undergo penile prosthesis implantation with particular interests to the patients characteristics. The conservative management of the priapic episode consists of a sympathomimetic agent in the first istance.Failure or recurrence of priapism following these conservative measures is an indication for surgical management. Shunt procedures between the corpora cavernosa and the neighbouring structures are often used first line; however, in refractory ischemic priapism the success rate is minimal. In such cases (> 48 h) an indication of immediate placement of a penile prosthesis could be the best solution.Keywords: refractory ischemic priapism, erectile dysfunction, priapism, penile prosthesis

Published
2022
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15. A Unique Case of Inflatable Penile Prosthesis (IPP) Implantation and Mesh Phalloplasty in a Patient Born with Congenital Fusiform Megalourethra

Author

Berrettini,Alfredo, Paraboschi,Irene, Di Grazia,Massimo, Gnech,Michele, Mantica,Guglielmo, Minoli,Dario Guido, De Marco,Erika Adalgisa, Manzoni,Gianantonio, Capece,Marco, Palmieri,Alessandro, Ralph,David, and Mirone,Vincenzo

Subjects
Research and Reports in Urology
Abstract

Alfredo Berrettini,1 Irene Paraboschi,1 Massimo Di Grazia,1 Michele Gnech,1 Guglielmo Mantica,2 Dario Guido Minoli,1 Erika Adalgisa De Marco,1 Gianantonio Manzoni,1 Marco Capece,3 Alessandro Palmieri,3 David Ralph,3 Vincenzo Mirone3 1Department of Pediatric Urology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; 2Department of Urology, IRCCS Ospedale Policlinico San Martino, Genova, Italy; 3Department of Urology, Azienda Ospedaliera Universitaria “Federico II”, Napoli, ItalyCorrespondence: Irene Paraboschi, Department of Pediatric Urology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, Milano, Italy, Tel +393313229495, Email irene.paraboschi01@gmail.comAbstract: We present the first case of a patient born with congenital fusiform megalourethra who underwent the successful placement of an inflatable penile prosthesis (IPP) and mesh phalloplasty due to primary erectile dysfunction (ED). After an extensive psychosexual assessment and a preoperative MRI scan, an IPP was successfully implanted. The procedure was carried out through a penoscrotal approach, which offered excellent exposure to the crura and the proximal ends of the corpora cavernosa. Following the incision and the dilatation of both corpora cavernosa, the penile cylinders were inserted and a mesh phalloplasty was performed, to replace the erectile tissues lacking in the distal corpora cavernosa. After reservoir and pump placement, the device was tested, and no mechanical issues were recorded. The postoperative course was uneventful, and, at the 2-year follow-up, the patient reported highly satisfactory results, with valid functional erections.Keywords: congenital fusiform megalourethra, inflatable penile prosthesis, phalloplasty, erectile dysfunction

Published
2023

16. Voice Assistants as Consultants for Male Patients with Sexual Dysfunction: A Reliable Option?

Author

Napolitano, Luigi, primary, Barone, Biagio, additional, Spirito, Lorenzo, additional, Trama, Francesco, additional, Pandolfo, Savio Domenico, additional, Capece, Marco, additional, García-Rojo, Esther, additional, Fernández-Pascual, Esaú, additional, Crocetto, Felice, additional, Fusco, Ferdinando, additional, De Sio, Marco, additional, Arcaniolo, Davide, additional, and Manfredi, Celeste, additional

Published
2023
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17. Immunotherapy for Urological Tumors on YouTubeTM: An Information-Quality Analysis

Author

Di Bello, Francesco, primary, Di Mauro, Ernesto, additional, Collà Ruvolo, Claudia, additional, Creta, Massimiliano, additional, La Rocca, Roberto, additional, Celentano, Giuseppe, additional, Capece, Marco, additional, Napolitano, Luigi, additional, Fraia, Agostino, additional, Pezone, Gabriele, additional, Morra, Simone, additional, Imbimbo, Ciro, additional, Mirone, Vincenzo, additional, Longo, Nicola, additional, and Califano, Gianluigi, additional

Published
2022
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19. Perceptions and attitudes toward the use of telemedicine for the postoperative outpatient urological care during the COVID-19 pandemic in an Academic Hospital in Southern Italy

Author

Mirone, Vincenzo, primary, Celentano, Giuseppe, additional, Collà Ruvolo, Claudia, additional, Cirillo, Luigi, additional, Fusco, Giovanni Maria, additional, Abate, Marco, additional, Morra, Simone, additional, Di Bello, Francesco, additional, Califano, Gianluigi, additional, Mirone, Claudia, additional, Cacace, Gianluigi, additional, Morgera, Vincenzo, additional, La Rocca, Roberto, additional, Capece, Marco, additional, Longo, Nicola, additional, Napolitano, Luigi, additional, and Creta, Massimiliano, additional

Published
2022
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20. Penile Implants: A Lesson from the First 50 Years

Author

Giordano, Alessandro, primary, Capece, Marco, additional, D’Alterio, Carlo, additional, di Giovanni, Angelo, additional, Zimarra, Assunta, additional, Napolitano, Luigi, additional, Marino, Claudio, additional, La Rocca, Roberto, additional, Creta, Massimiliano, additional, Cai, Tommaso, additional, and Palmieri, Alessandro, additional

Published
2022
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22. Perioperative Red Cell Line Trend following Robot-Assisted Radical Prostatectomy for Prostate Cancer

Author

Di Bello, Francesco, primary, Di Mauro, Ernesto, additional, Collà Ruvolo, Claudia, additional, Creta, Massimiliano, additional, La Rocca, Roberto, additional, Celentano, Giuseppe, additional, Capece, Marco, additional, Napolitano, Luigi, additional, Morra, Simone, additional, Pezone, Gabriele, additional, Passaro, Francesco, additional, De Luca, Ciro, additional, Mangiapia, Francesco, additional, Logrieco, Nicola, additional, Buonanno, Pasquale, additional, Servillo, Giuseppe, additional, Imbimbo, Ciro, additional, Mirone, Vincenzo, additional, Longo, Nicola, additional, and Califano, Gianluigi, additional

Published
2022
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23. ‘Hanger‑shaped’ scrotectomy: A novel technique for the management of penoscrotal lymphedema: A case report

Author

Capece, Marco, primary, Giovanni, Angelo, additional, Creta, Massimiliano, additional, Giordano, Alessandro, additional, D'alterio, Carlo, additional, Palmieri, Alessandro, additional, Cirigliano, Lorenzo, additional, Napolitano, Luigi, additional, Mirone, Claudia, additional, Orlandino, Gianfranco, additional, Celentano, Giuseppe, additional, Califano, Gianluigi, additional, Cirillo, Luigi, additional, Marino, Claudio, additional, Fusco, Giovanni, additional, Mirone, Vincenzo, additional, and Rocca, Roberto, additional

Published
2022
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24. Could YouTubeTM encourage men on prostate checks? A contemporary analysis

Author

Morra, Simone, primary, Napolitano, Luigi, additional, Collà Ruvolo, Claudia, additional, Celentano, Giuseppe, additional, La Rocca, Roberto, additional, Capece, Marco, additional, Creta, Massimiliano, additional, Passaro, Francesco, additional, Di Bello, Francesco, additional, Cirillo, Luigi, additional, Turco, Carmine, additional, Di Mauro, Ernesto, additional, Pezone, Gabriele, additional, Fraia, Agostino, additional, Mangiapia, Francesco, additional, Fusco, Ferdinando, additional, Mirone, Vincenzo, additional, Califano, Gianluigi, additional, and Longo, Nicola, additional

Published
2022
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25. Current Evidence on the Use of Hyaluronic Acid as Nonsurgical Option for the Treatment of Peyronie's Disease: A Contemporary Review.

Author

Capece, Marco, Celentano, Giuseppe, and La Rocca, Roberto

Subjects
*PENILE induration, *HYALURONIC acid, *PENILE prostheses, *PENIS curvatures, *IMPOTENCE
Abstract

Peyronie's disease is a condition characterized by the formation of fibrous plaques in the tunica albuginea, which can cause pain, curvature, and erectile dysfunction. Preclinical studies have demonstrated the potential benefits of hyaluronic acid in treating Peyronie's disease, including antifibrotic, anti-inflammatory, and proangiogenic effects, although more research is needed to fully understand its mechanisms of action. Clinical studies have shown promising results, with hyaluronic acid injections leading to improvements in plaque size, penile curvature, and erectile function, and being well tolerated by patients. The findings suggest that HA injections could be a viable and safe treatment option for Peyronie's disease, particularly in the early stages of the disease. However, more research is needed to determine the optimal dosage and treatment duration for HA injections, and to confirm its efficacy in the stable phase of Peyronie's disease. Overall, hyaluronic acid is a potentially effective therapy for Peyronie's disease, with the ability to inhibit fibrosis and promote angiogenesis, and low risk of adverse effects, making it an attractive option for patients who are unable or unwilling to undergo surgery. [ABSTRACT FROM AUTHOR]

Published
2023
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26. Erectile dysfunction and mobile phone applications: Quality, content and adherence to European Association guidelines on male sexual dysfunction

Author

Napolitano, Luigi, primary, Fusco, Giovanni Maria, additional, Cirillo, Luigi, additional, Abate, Marco, additional, Mirone, Claudia, additional, Barone, Biagio, additional, Celentano, Giuseppe, additional, La Rocca, Roberto, additional, Mirone, Vincenzo, additional, Creta, Massimiliano, additional, and Capece, Marco, additional

Published
2022
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27. Machine Learning and Clinical-Radiological Characteristics for the Classification of Prostate Cancer in PI-RADS 3 Lesions

Author

Gravina, Michela, primary, Spirito, Lorenzo, additional, Celentano, Giuseppe, additional, Capece, Marco, additional, Creta, Massimiliano, additional, Califano, Gianluigi, additional, Collà Ruvolo, Claudia, additional, Morra, Simone, additional, Imbriaco, Massimo, additional, Di Bello, Francesco, additional, Sciuto, Antonio, additional, Cuocolo, Renato, additional, Napolitano, Luigi, additional, La Rocca, Roberto, additional, Mirone, Vincenzo, additional, Sansone, Carlo, additional, and Longo, Nicola, additional

Published
2022
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28. Prostate Cancer Diagnosis, Treatment and Outcomes in Patients with Previous or Synchronous Colorectal Cancer: A Systematic Review of Published Evidence

Author

Celentano, Giuseppe, primary, Creta, Massimiliano, additional, Napolitano, Luigi, additional, Abate, Marco, additional, La Rocca, Roberto, additional, Capece, Marco, additional, Mirone, Claudia, additional, Morra, Simone, additional, Di Bello, Francesco, additional, Cirillo, Luigi, additional, Mangiapia, Francesco, additional, Califano, Gianluigi, additional, Collà Ruvolo, Claudia, additional, Sagnelli, Caterina, additional, Sica, Antonello, additional, Calogero, Armando, additional, Iacono, Fabrizio, additional, Fusco, Ferdinando, additional, Mirone, Vincenzo, additional, and Longo, Nicola, additional

Published
2022
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29. Male Sexual Dysfunction and Infertility in Spinal Cord Injury Patients: State-of-the-Art and Future Perspectives

Author

Di Bello, Francesco, primary, Creta, Massimiliano, additional, Napolitano, Luigi, additional, Califano, Gianluigi, additional, Passaro, Francesco, additional, Morra, Simone, additional, Giovanni, Angelo di, additional, Fusco, Giovanni Maria, additional, Cirillo, Luigi, additional, Abate, Marco, additional, Morgera, Vincenzo, additional, Cacace, Gianluigi, additional, De Luca, Luigi, additional, Spena, Gianluca, additional, Collà Ruvolo, Claudia, additional, Calace, Francesco Paolo, additional, Manfredi, Celeste, additional, La Rocca, Roberto, additional, Celentano, Giuseppe, additional, Turco, Carmine, additional, Capece, Marco, additional, D’Alterio, Carlo, additional, Giordano, Alessandro, additional, Mauro, Ernesto di, additional, Trama, Francesco, additional, Amicuzi, Ugo, additional, Arcaniolo, Davide, additional, Fusco, Ferdinando, additional, and Longo, Nicola, additional

Published
2022
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30. Metastasis-Directed Radiation Therapy with Consolidative Intent for Oligometastatic Urothelial Carcinoma: A Systematic Review and Meta-Analysis

Author

Longo, Nicola, primary, Celentano, Giuseppe, additional, Napolitano, Luigi, additional, La Rocca, Roberto, additional, Capece, Marco, additional, Califano, Gianluigi, additional, Collà Ruvolo, Claudia, additional, Mangiapia, Francesco, additional, Fusco, Ferdinando, additional, Morra, Simone, additional, Turco, Carmine, additional, Di Bello, Francesco, additional, Fusco, Giovanni Maria, additional, Cirillo, Luigi, additional, Cacciapuoti, Crescenzo, additional, Spirito, Lorenzo, additional, Calogero, Armando, additional, Sica, Antonello, additional, Sagnelli, Caterina, additional, and Creta, Massimiliano, additional

Published
2022
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31. COVID-19 Quarantine Dramatically Affected Male Sexual Behavior: Is There a Possibility to Go Back to Normality?

Author

Spirito, Lorenzo, primary, Morelli, Michele, additional, La Rocca, Roberto, additional, Napolitano, Luigi, additional, Ruvolo, Claudia Collà, additional, Romano, Lorenzo, additional, di Giovanni, Angelo, additional, Sciorio, Carmine, additional, Concetti, Sergio, additional, Montanari, Emanuele, additional, Tripodi, Francesca, additional, Fusco, Ferdinando, additional, and Capece, Marco, additional

Published
2022
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32. Looking for cystoscopy on YouTube: Are videos a reliable information tool for internet users?

Author

Turco, Carmine, primary, Collà Ruvolo, Claudia, additional, Cilio, Simone, additional, Celentano, Giuseppe, additional, Califano, Gianluigi, additional, Creta, Massimiliano, additional, Capece, Marco, additional, La Rocca, Roberto, additional, Napolitano, Luigi, additional, Mangiapia, Francesco, additional, Spirito, Lorenzo, additional, Morra, Simone, additional, Melchionna, Alberto, additional, Fusco, Ferdinando, additional, Mirone, Vincenzo, additional, and Longo, Nicola, additional

Published
2022
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33. Penile Implants: A Lesson from the First 50 Years.

Author

Giordano, Alessandro, Capece, Marco, D'Alterio, Carlo, di Giovanni, Angelo, Zimarra, Assunta, Napolitano, Luigi, Marino, Claudio, La Rocca, Roberto, Creta, Massimiliano, Cai, Tommaso, and Palmieri, Alessandro

Subjects
*PENILE prostheses, *IMPOTENCE, *PERIOPERATIVE care, *PATIENT satisfaction, *OPERATIVE surgery
Abstract

This year marks the fiftieth anniversary of the first implant of an inflatable penile prosthesis (IPP). The authors of this paper want to celebrate the event with a narrative review of the current literature. The main scopes are antibiotic prophylaxis, patient satisfaction, and future developments. The implant of the first IPP in 1973, performed by Branteley Scott was a turning point in the history of penile prosthesis, revolutionizing the treatment of erectile dysfunction (ED). Since then, the idea of an inflatable device has not changed much. However, the innovations in design, materials, surgical techniques, and perioperative management led to a more natural, durable, and reliable device featuring fewer complications and greater patient satisfaction. Currently, IPP is associated with high patient satisfaction and excellent long-term outcomes, remaining the gold standard for men with refractory ED. Several strategies are under investigation to improve the technology of penile prosthesis, and we expect in the next future the introduction of new devices that are easier to activate, discreet, comfortable when deflated, and durable in time, mimicking a more physiological erection. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Incidence and Predicting Factors of Histopathological Features at Robot-Assisted Radical Prostatectomy in the mpMRI Era: Results of a Single Tertiary Referral Center.

Author

Di Mauro, Ernesto, Di Bello, Francesco, Califano, Gianluigi, Morra, Simone, Creta, Massimiliano, Celentano, Giuseppe, Abate, Marco, Fraia, Agostino, Pezone, Gabriele, Marino, Claudio, Cilio, Simone, Capece, Marco, La Rocca, Roberto, Imbimbo, Ciro, Longo, Nicola, and Colla' Ruvolo, Claudia

Subjects
RADICAL prostatectomy, PROSTATE cancer, SURGICAL robots, HISTOPATHOLOGY, PROSTATE biopsy, REGRESSION analysis
Abstract

Background and Objectives: To describe the predictors of cribriform variant status and perineural invasion (PNI) in robot-assisted radical prostatectomy (RARP) histology. To define the rates of upgrading between biopsy specimens and final histology and their possible predictive factors in prostate cancer (PCa) patients undergoing RARP. Material and Methods: Within our institutional database, 265 PCa patients who underwent prostate biopsies and consecutive RARP at our center were enrolled (2018–2022). In the overall population, two independent multivariable logistic regression models (LRMs) predicting the presence of PNI or cribriform variant status at RARP were performed. In low- and intermediate-risk PCa patients according to D'Amico risk classification, three independent multivariable LRMs were fitted to predict upgrading. Results: Of all, 30.9% were low-risk, 18.9% were intermediate-risk and 50.2% were high-risk PCa patients. In the overall population, the rates of the cribriform variant and PNI at RARP were 55.8% and 71.1%, respectively. After multivariable LRMs predicting PNI, total tumor length in biopsy cores (>24 mm [OR: 2.37, p-value = 0.03], relative to <24 mm) was an independent predictor. After multivariable LRMs predicting cribriform variant status, PIRADS (3 [OR:15.37], 4 [OR: 13.57] or 5 [OR: 16.51] relative to PIRADS 2, all p = 0.01) and total tumor length in biopsy cores (>24 mm [OR: 2.47, p = 0.01], relative to <24 mm) were independent predicting factors. In low- and intermediate-risk PCa patients, the rate of upgrading was 74.4% and 78.0%, respectively. After multivariable LRMs predicting upgrading, PIRADS (PIRADS 3 [OR: 7.01], 4 [OR: 16.98] or 5 [OR: 20.96] relative to PIRADS 2, all p = 0.01) was an independent predicting factor. Conclusions: RARP represents a tailored and risk-adapted treatment strategy for PCa patients. The indication of RP progressively migrates to high-risk PCa after a pre-operative assessment. Specifically, the PIRADS score at mpMRI should guide the decision-making process of urologists for PCa patients. [ABSTRACT FROM AUTHOR]

Published
2023
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35. Toxicity of Antioxidant Supplements in Patients with Male Factor Infertility: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Author

Creta, Massimiliano, primary, Arcaniolo, Davide, additional, Celentano, Giuseppe, additional, Napolitano, Luigi, additional, La Rocca, Roberto, additional, Capece, Marco, additional, Califano, Gianluigi, additional, Mangiapia, Francesco, additional, Spirito, Lorenzo, additional, Crocetto, Felice, additional, Imbimbo, Ciro, additional, Longo, Nicola, additional, De Sio, Marco, additional, and Fusco, Ferdinando, additional

Published
2021
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36. Telementoring for communication between residents and faculty physicians: Results from a survey on attitudes and perceptions in an Academic Tertiary Urology Referral Department in Italy

Author

Mirone, Vincenzo, primary, Creta, Massimiliano, additional, Capece, Marco, additional, Celentano, Giuseppe, additional, Califano, Gianluigi, additional, Collà Ruvolo, Claudia, additional, Spirito, Lorenzo, additional, Fusco, Giovanni Maria, additional, Cirillo, Luigi, additional, Longo, Nicola, additional, Fusco, Ferdinando, additional, Mirone, Claudia, additional, La Rocca, Roberto, additional, and Napolitano, Luigi, additional

Published
2021
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37. Impact of Circadian Desynchrony on Spermatogenesis: A Mini Review

Author

Fusco, Ferdinando, primary, Longo, Nicola, additional, De Sio, Marco, additional, Arcaniolo, Davide, additional, Celentano, Giuseppe, additional, Capece, Marco, additional, La Rocca, Roberto, additional, Mangiapia, Francesco, additional, Califano, Gianluigi, additional, Morra, Simone, additional, Turco, Carmine, additional, Spena, Gianluca, additional, Spirito, Lorenzo, additional, Fusco, Giovanni Maria, additional, Cirillo, Luigi, additional, De Luca, Luigi, additional, Napolitano, Luigi, additional, Mirone, Vincenzo, additional, and Creta, Massimiliano, additional

Published
2021
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38. Robot-Aided Prostate Cancer Diagnosis with Fiber Optic Sensing: A Validation Study on Phantoms and Ex-Vivo Tissues

Author

Pecorella, Claudia, primary, Cirillo, Andrea, additional, Siciliano, Bruno, additional, Iele, Antonio, additional, Ricciardi, Armando, additional, Consales, Marco, additional, Cusano, Andrea, additional, Capece, Marco, additional, Celentano, Giuseppe, additional, La Rocca, Roberto, additional, Mirone, Vincenzo, additional, and Ficuciello, Fanny, additional

Published
2021
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39. Immunotherapy for Urological Tumors on YouTube TM : An Information-Quality Analysis.

Author

Di Bello, Francesco, Di Mauro, Ernesto, Collà Ruvolo, Claudia, Creta, Massimiliano, La Rocca, Roberto, Celentano, Giuseppe, Capece, Marco, Napolitano, Luigi, Fraia, Agostino, Pezone, Gabriele, Morra, Simone, Imbimbo, Ciro, Mirone, Vincenzo, Longo, Nicola, and Califano, Gianluigi

Subjects
PROSTATE cancer, RENAL cell carcinoma, RENAL cancer, CROWDSOURCING, TRANSITIONAL cell carcinoma, IMMUNOTHERAPY
Abstract

Background: YouTubeTM is an open-access source for mass information. Several previous studies of YouTubeTM videos showed a high rate of misinformation in the urological field. The aim of the current study was to evaluate the quality of information on immunotherapy (IMT) for urological tumors uploaded to YouTubeTM. Methods: YouTubeTM videos were searched using nine keyword combinations. The PEMAT, the DISCERN tool, and the Misinformation scale were used to assess the quality of information in YouTubeTM videos about IMT for urological tumors. Descriptive statistics and Kruskal–Wallis, Chi-square, proportion, and Pearson's tests were performed. Results: According to the selection criteria, 156 YouTubeTM videos were suitable for the analysis and stratified according to topic (urothelial carcinoma vs. renal cell cancer vs. prostate cancer vs. general information on IMT). According to PEMAT A/V, the overall Understandability score was 40% (Inter-Quartile Range [IQR]: 20–61.5) and the overall Actionability score was 0% (IQR: 0–25). According to the DISCERN tool, the overall DISCERN score was 44 (IQR: 39–53.2), defined as "fair". According to the Misinformation scale, we recorded the lowest median overall score for item 4 ("IMT in multimodality approach") and item 5 ("Future perspective"). Conclusions: YouTubeTM cannot be recommended as a reliable source of information on IMT for urological malignancies. In addition, YouTubeTM videos contributed to the spread of misinformation by underestimating the role of IMT in a multimodality approach and missing the findings of published clinical trial results. [ABSTRACT FROM AUTHOR]

Published
2023
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40. Fournier’s Gangrene in Patients with Oncohematological Diseases: A Systematic Review of Published Cases

Author

Creta, Massimiliano, primary, Sica, Antonello, additional, Napolitano, Luigi, additional, Celentano, Giuseppe, additional, La Rocca, Roberto, additional, Capece, Marco, additional, Calogero, Armando, additional, Califano, Gianluigi, additional, Vanni, Luigi, additional, Mangiapia, Francesco, additional, Arcaniolo, Davide, additional, Spirito, Lorenzo, additional, Fusco, Ferdinando, additional, De Sio, Marco, additional, Imbimbo, Ciro, additional, Mirone, Vincenzo, additional, Sagnelli, Caterina, additional, and Longo, Nicola, additional

Published
2021
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42. Focus on Silodosin: Pros and Cons of Uroselectivity

Author

Califano,Gianluigi, Collà Ruvolo,Claudia, Creta,Massimiliano, Capece,Marco, La Rocca,Roberto, Celentano,Giuseppe, Napolitano,Luigi, Calace,Francesco Paolo, Spena,Gianluca, Trama,Francesco, Crocetto,Felice, Mangiapia,Francesco, Longo,Nicola, and Fusco,Ferdinando

Subjects
Research and Reports in Urology
Abstract

Gianluigi Califano,1 Claudia Collà Ruvolo,1 Massimiliano Creta,1 Marco Capece,1 Roberto La Rocca,1 Giuseppe Celentano,1 Luigi Napolitano,1 Francesco Paolo Calace,1 Gianluca Spena,1 Francesco Trama,1 Felice Crocetto,1 Francesco Mangiapia,1 Nicola Longo,1 Ferdinando Fusco2 1Department of Neurosciences, Reproductive Sciences and Odontostomatology – Federico II University of Naples, Naples, Italy; 2Department of Urology, Luigi Vanvitelli University of Naples, Naples, ItalyCorrespondence: Massimiliano CretaDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University of Naples Federico II, via Sergio Pansini 5, Naples 80131, ItalyTel/Fax +390817462611Email max.creta@gmail.comAbstract: Medical management of lower urinary tract symptoms related to benign prostatic obstruction engages healthcare professionals worldwide. Currently, alpha-1 adrenergic antagonists are strongly recommended as first-line therapy for patients with moderate to severe symptoms because of their safety, efficacy and good tolerability. These agents are highly heterogeneous in terms of pharmacological selectivity for the adrenergic receptor subtypes with silodosin being the agent characterized by the highest α1A/α1B affinity ratio. This property has been proposed to confer to silodosin advantages in terms of bladder outlet obstruction improvement and lower incidence of cardiovascular side effects at the cost of a higher incidence of ejaculatory dysfunction. These aspects should be carefully taken in consideration when personalizing medical therapy for lower urinary tract symptoms related to benign prostatic obstruction.Keywords: alpha-1 adrenergic antagonists, benign prostate enlargement, lower urinary tract symptoms, bladder outlet obstruction

Published
2020

44. Inhibition of Androgen Signalling Improves the Outcomes of Therapies for Bladder Cancer: Results from a Systematic Review of Preclinical and Clinical Evidence and Meta-Analysis of Clinical Studies

Author

Creta, Massimiliano, primary, Celentano, Giuseppe, additional, Napolitano, Luigi, additional, La Rocca, Roberto, additional, Capece, Marco, additional, Califano, Gianluigi, additional, Collà Ruvolo, Claudia, additional, Mangiapia, Francesco, additional, Morra, Simone, additional, Turco, Carmine, additional, Spirito, Lorenzo, additional, Fusco, Ferdinando, additional, Imbimbo, Ciro, additional, Mirone, Vincenzo, additional, and Longo, Nicola, additional

Published
2021
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45. Hypogonadism in Patients with Prader Willi Syndrome: A Narrative Review

Author

Napolitano, Luigi, primary, Barone, Biagio, additional, Morra, Simone, additional, Celentano, Giuseppe, additional, La Rocca, Roberto, additional, Capece, Marco, additional, Morgera, Vincenzo, additional, Turco, Carmine, additional, Caputo, Vincenzo Francesco, additional, Spena, Gianluca, additional, Romano, Lorenzo, additional, De Luca, Luigi, additional, Califano, Gianluigi, additional, Collà Ruvolo, Claudia, additional, Mangiapia, Francesco, additional, Mirone, Vincenzo, additional, Longo, Nicola, additional, and Creta, Massimiliano, additional

Published
2021
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46. Attitudes and perceptions towards multiparametric magnetic resonance imaging of the prostate: A national survey among Italian urologists

Author

Stanzione, Arnaldo, primary, Creta, Massimiliano, additional, Imbriaco, Massimo, additional, La Rocca, Roberto, additional, Capece, Marco, additional, Esposito, Fabio, additional, Imbimbo, Ciro, additional, Fusco, Ferdinando, additional, Celentano, Giuseppe, additional, Napolitano, Luigi, additional, Mangiapia, Francesco, additional, Mirone, Vincenzo, additional, and Longo, Nicola, additional

Published
2020
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47. Clinical and Pathological Characteristics of Metastatic Renal Cell Carcinoma Patients Needing a Second-Line Therapy: A Systematic Review

Author

Longo, Nicola, primary, Capece, Marco, additional, Celentano, Giuseppe, additional, La Rocca, Roberto, additional, Califano, Gianluigi, additional, Collà Ruvolo, Claudia, additional, Buonerba, Carlo, additional, Esposito, Fabio, additional, Napolitano, Luigi, additional, Mangiapia, Francesco, additional, Fusco, Ferdinando, additional, Mirone, Vincenzo, additional, and Creta, Massimiliano, additional

Published
2020
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48. Outcomes of Renal Stone Surgery Performed Either as Predonation or Ex Vivo Bench Procedure in Renal Grafts from Living Donors: A Systematic Review

Author

Longo, Nicola, primary, Calogero, Armando, additional, Creta, Massimiliano, additional, Celentano, Giuseppe, additional, Napolitano, Luigi, additional, Capece, Marco, additional, La Rocca, Roberto, additional, Sagnelli, Caterina, additional, Carlomagno, Nicola, additional, Peluso, Gaia, additional, Pagano, Teresa, additional, Campanile, Silvia, additional, Dodaro, Concetta Anna, additional, Sica, Antonello, additional, Califano, Gianluigi, additional, Crocetto, Felice, additional, Fusco, Ferdinando, additional, Mangiapia, Francesco, additional, and Santangelo, Michele, additional

Published
2020
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49. Tamsulosin plus a new complementary and alternative medicine in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: Results from a retrospective comparative study

Author

Fusco, Ferdinando, primary, Creta, Massimiliano, additional, Trama, Francesco, additional, Esposito, Fabio, additional, Crocetto, Felice, additional, Aveta, Achille, additional, Mangiapia, Francesco, additional, Imbimbo, Ciro, additional, Capece, Marco, additional, La Rocca, Roberto, additional, Mirone, Vincenzo, additional, and Longo, Nicola, additional

Published
2020
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50. Short- and Long-Term Evaluation of Renal Function after Radical Cystectomy and Cutaneous Ureterostomy in High-Risk Patients

Author

Creta, Massimiliano, primary, Fusco, Ferdinando, additional, La Rocca, Roberto, additional, Capece, Marco, additional, Celentano, Giuseppe, additional, Imbimbo, Ciro, additional, Imperatore, Vittorio, additional, Russo, Luigi, additional, Mangiapia, Francesco, additional, Mirone, Vincenzo, additional, Russo, Domenico, additional, and Longo, Nicola, additional

Published
2020
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