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Testing and evaluation is an important step before the large-scale application of the autonomous driving systems (ADSs). Based on the three level of scenario abstraction theory, a testing can be performed within a logical scenario, followed by an evaluation stage which is inputted with the testing results of each concrete scenario generated from the logical parameter space. During the above process, abundant testing information is produced which is beneficial for comprehensive and accurate evaluations. To make full use of testing information, this paper proposes an Integrated accelerated Testing and Evaluation Method (ITEM). Based on a Monte Carlo Tree Search (MCTS) paradigm and a dual surrogates testing framework proposed in our previous work, this paper applies the intermediate information (i.e., the tree structure, including the affiliation of each historical sampled point with the subspaces and the parent-child relationship between subspaces) generated during the testing stage into the evaluation stage to achieve accurate hazardous domain identification. Moreover, to better serve this purpose, the UCB calculation method is improved to allow the search algorithm to focus more on the hazardous domain boundaries. Further, a stopping condition is constructed based on the convergence of the search algorithm. Ablation and comparative experiments are then conducted to verify the effectiveness of the improvements and the superiority of the proposed method. The experimental results show that ITEM could well identify the hazardous domains in both low- and high-dimensional cases, regardless of the shape of the hazardous domains, indicating its generality and potential for the safety evaluation of ADSs., Comment: 15 pages, 11 figures more...

The degraded performance and group unfairness caused by confounding sensitive attributes in rumor detection remains relatively unexplored. To address this, we propose a two-step framework. Initially, it identifies confounding sensitive attributes that limit rumor detection performance and cause unfairness across groups. Subsequently, we aim to learn equally informative representations through invariant learning. Our method considers diverse sets of groups without sensitive attribute annotations. Experiments show our method easily integrates with existing rumor detectors, significantly improving both their detection performance and fairness. more...

3D Gaussian Splatting (3DGS) has demonstrated impressive performance in scene reconstruction. However, most existing GS-based surface reconstruction methods focus on 3D objects or limited scenes. Directly applying these methods to large-scale scene reconstruction will pose challenges such as high memory costs, excessive time consumption, and lack of geometric detail, which makes it difficult to implement in practical applications. To address these issues, we propose a multi-agent collaborative fast 3DGS surface reconstruction framework based on distributed learning for large-scale surface reconstruction. Specifically, we develop local model compression (LMC) and model aggregation schemes (MAS) to achieve high-quality surface representation of large scenes while reducing GPU memory consumption. Extensive experiments on Urban3d, MegaNeRF, and BlendedMVS demonstrate that our proposed method can achieve fast and scalable high-fidelity surface reconstruction and photorealistic rendering. Our project page is available at \url{https://gyy456.github.io/CoSurfGS}., Comment: Our project page is available at \url{https://gyy456.github.io/CoSurfGS} more...

Scenario-based virtual testing is one of the most significant methods to test and evaluate the safety of automated driving systems (ADSs). However, it is impractical to enumerate all concrete scenarios in a logical scenario space and test them exhaustively. Recently, Black-Box Optimization (BBO) was introduced to accelerate the scenario-based test of ADSs by utilizing the historical test information to generate new test cases. However, a single optimum found by the BBO algorithm is insufficient for the purpose of a comprehensive safety evaluation of ADSs in a logical scenario. In fact, all the subspaces representing danger in the logical scenario space, rather than only the most critical concrete scenario, play a more significant role for the safety evaluation. Covering as many of the critical concrete scenarios in a logical scenario space through a limited number of tests is defined as the Black-Box Coverage (BBC) problem in this paper. We formalized this problem in a sample-based search paradigm and constructed a coverage criterion with Confusion Matrix Analysis. Furthermore, we propose LAMBDA (Latent-Action Monte-Carlo Beam Search with Density Adaption) to solve BBC problems. LAMBDA can quickly focus on critical subspaces by recursively partitioning the logical scenario space into accepted and rejected parts. Compared with its predecessor LaMCTS, LAMBDA introduces sampling density to overcome the sampling bias from optimization and Beam Search to obtain more parallelizability. Experimental results show that LAMBDA achieves state-of-the-art performance among all baselines and can reach at most 33 and 6000 times faster than Random Search to get 95% coverage of the critical areas in 2- and 5-dimensional synthetic functions, respectively. Experiments also demonstrate that LAMBDA has a promising future in the safety evaluation of ADSs in virtual tests., Comment: 17pages, 21figures more...

Spatial intelligence is the ability of a machine to perceive, reason, and act in three dimensions within space and time. Recent advancements in large-scale auto-regressive models have demonstrated remarkable capabilities across various reasoning tasks. However, these models often struggle with fundamental aspects of spatial reasoning, particularly in answering questions like "Where am I?" and "What will I see?". While some attempts have been done, existing approaches typically treat them as separate tasks, failing to capture their interconnected nature. In this paper, we present Generative Spatial Transformer (GST), a novel auto-regressive framework that jointly addresses spatial localization and view prediction. Our model simultaneously estimates the camera pose from a single image and predicts the view from a new camera pose, effectively bridging the gap between spatial awareness and visual prediction. The proposed innovative camera tokenization method enables the model to learn the joint distribution of 2D projections and their corresponding spatial perspectives in an auto-regressive manner. This unified training paradigm demonstrates that joint optimization of pose estimation and novel view synthesis leads to improved performance in both tasks, for the first time, highlighting the inherent relationship between spatial awareness and visual prediction. more...

In mammalian cells, repair centers for DNA double-strand breaks (DSBs) have been identified. However, previous researches predominantly rely on methods that induce specific DSBs by cutting particular DNA sequences. The clustering and its spatiotemporal properties of non-specifically DSBs, especially those induced by environmental stresses such as irradiation, remains unclear. In this study, we used Dragonfly microscopy to induce high-precision damage in cells and discovered that DSB clustering during the early stages of DNA damage response (DDR) and repair, but not during the repair plateau phase. Early in DDR, DSB clustered into existing 53BP1 foci. The DSB clustering at different stages has different implications for DNA repair. By controlling the distance between adjacent damage points, we found that the probability of DSB clustering remains constant at distances of 0.8 - 1.4 um, while clustering does not occur beyond 1.4 um. Within the 0.8 um range, the probability of clustering significantly increases due to the phase separation effect of 53BP1. Using a Monte Carlo approach, we developed a dynamic model of 53BP1 foci formation, fission, and fusion. This model accurately predicts experimental outcomes and further demonstrates the temporal and spatial influences on DSB clustering. These results showed that, similarly to specifically induced DSBs, non-specifically induced DSBs can also cluster. The extent of DSB clustering is influenced by both temporal and spatial factors, which provide new insights into the dynamics of DSB clustering and the role of 53BP1 in DNA repair processes. Such findings could enhance our understanding of DNA damage responses and help us improve DNA repair therapies in disease. more...

In recent years, Recommender Systems (RS) have witnessed a transformative shift with the advent of Large Language Models (LLMs) in the field of Natural Language Processing (NLP). Models such as GPT-3.5/4, Llama, have demonstrated unprecedented capabilities in understanding and generating human-like text. The extensive information pre-trained by these LLMs allows for the potential to capture a more profound semantic representation from different contextual information of users and items. While the great potential lies behind the thriving of LLMs, the challenge of leveraging user-item preferences from contextual information and its alignment with the improvement of Recommender Systems needs to be addressed. Believing that a better understanding of the user or item itself can be the key factor in improving recommendation performance, we conduct research on generating informative profiles using state-of-the-art LLMs. To boost the linguistic abilities of LLMs in Recommender Systems, we introduce the Prompting-Based Representation Learning Method for Recommendation (P4R). In our P4R framework, we utilize the LLM prompting strategy to create personalized item profiles. These profiles are then transformed into semantic representation spaces using a pre-trained BERT model for text embedding. Furthermore, we incorporate a Graph Convolution Network (GCN) for collaborative filtering representation. The P4R framework aligns these two embedding spaces in order to address the general recommendation tasks. In our evaluation, we compare P4R with state-of-the-art Recommender models and assess the quality of prompt-based profile generation., Comment: Risks: The 1st International Workshop on Risks, Opportunities, and Evaluation of Generative Models in Recommendation more...

Large Language Models (LLMs) have achieved remarkable success in various fields, prompting several studies to explore their potential in recommendation systems. However, these attempts have so far resulted in only modest improvements over traditional recommendation models. Moreover, three critical questions remain under-explored: firstly, the real value of LLMs' pre-trained weights, often considered to encapsulate world knowledge; secondly, the necessity of fine-tuning for recommendation tasks; lastly, whether LLMs can exhibit the same scalability benefits in recommendation systems as they do in other domains. In this paper, we propose a novel Hierarchical Large Language Model (HLLM) architecture designed to enhance sequential recommendation systems. Our approach employs a two-tier model: the first Item LLM extracts rich content features from the detailed text description of the item, while the second User LLM utilizes these features to predict users' future interests based on their interaction history. Extensive experiments demonstrate that our method effectively leverages the pre-trained capabilities of open-source LLMs, and further fine-tuning leads to significant performance boosts. Additionally, HLLM achieves excellent scalability, with the largest configuration utilizing 7B parameters for both item feature extraction and user interest modeling. Moreover, HLLM offers excellent training and serving efficiency, making it practical in real-world applications. Evaluations on two large-scale datasets, PixelRec and Amazon Reviews, show that HLLM achieves state-of-the-art results, outperforming traditional ID-based models by a wide margin. In online A/B testing, HLLM showcases notable gains, validating its practical impact in real-world recommendation scenarios. Codes are available at https://github.com/bytedance/HLLM. more...

3D Gaussian Splatting (3DGS) has shown promising performance in novel view synthesis. Previous methods adapt it to obtaining surfaces of either individual 3D objects or within limited scenes. In this paper, we make the first attempt to tackle the challenging task of large-scale scene surface reconstruction. This task is particularly difficult due to the high GPU memory consumption, different levels of details for geometric representation, and noticeable inconsistencies in appearance. To this end, we propose GigaGS, the first work for high-quality surface reconstruction for large-scale scenes using 3DGS. GigaGS first applies a partitioning strategy based on the mutual visibility of spatial regions, which effectively grouping cameras for parallel processing. To enhance the quality of the surface, we also propose novel multi-view photometric and geometric consistency constraints based on Level-of-Detail representation. In doing so, our method can reconstruct detailed surface structures. Comprehensive experiments are conducted on various datasets. The consistent improvement demonstrates the superiority of GigaGS. more...

FLASH radiotherapy (FLASH-RT) is a new modality of radiotherapy by delivering doses with ultra-high dose rates. FLASH-RT has the ability to suppress tumor growth while sparing normal tissues, known as the FLASH effect. Although FLASH effect has proved valid in various models by different ionizing radiations, the exact underlying mechanism is still unclear. This article summarizes mainstream hypotheses of FLASH effect at physicochemical and biological levels, including oxygen depletion and free radical reactions, nuclear and mitochondria damage, as well as immune response. These hypotheses contribute reasonable explanations to the FLASH effect, and are interconnected according to the chronological order of the organism's response to ionizing radiation. By collating the existing consensus, evidence, and hypotheses, this article provides a comprehensive overview of potential mechanisms of FLASH effect and practical guidance for future investigation in the field of FLASH-RT., Comment: 24 pages, 5 figures more...

In recent years, 3D Gaussian splatting has emerged as a powerful technique for 3D reconstruction and generation, known for its fast and high-quality rendering capabilities. To address these shortcomings, this paper introduces a novel diffusion-based framework, GVGEN, designed to efficiently generate 3D Gaussian representations from text input. We propose two innovative techniques:(1) Structured Volumetric Representation. We first arrange disorganized 3D Gaussian points as a structured form GaussianVolume. This transformation allows the capture of intricate texture details within a volume composed of a fixed number of Gaussians. To better optimize the representation of these details, we propose a unique pruning and densifying method named the Candidate Pool Strategy, enhancing detail fidelity through selective optimization. (2) Coarse-to-fine Generation Pipeline. To simplify the generation of GaussianVolume and empower the model to generate instances with detailed 3D geometry, we propose a coarse-to-fine pipeline. It initially constructs a basic geometric structure, followed by the prediction of complete Gaussian attributes. Our framework, GVGEN, demonstrates superior performance in qualitative and quantitative assessments compared to existing 3D generation methods. Simultaneously, it maintains a fast generation speed ($\sim$7 seconds), effectively striking a balance between quality and efficiency. Our project page is: https://gvgen.github.io/, Comment: ECCV 2024 more...

In recent years, Recommender Systems(RS) have witnessed a transformative shift with the advent of Large Language Models(LLMs) in the field of Natural Language Processing(NLP). These models such as OpenAI's GPT-3.5/4, Llama from Meta, have demonstrated unprecedented capabilities in understanding and generating human-like text. This has led to a paradigm shift in the realm of personalized and explainable recommendations, as LLMs offer a versatile toolset for processing vast amounts of textual data to enhance user experiences. To provide a comprehensive understanding of the existing LLM-based recommendation systems, this survey aims to analyze how RS can benefit from LLM-based methodologies. Furthermore, we describe major challenges in Personalized Explanation Generating(PEG) tasks, which are cold-start problems, unfairness and bias problems in RS. more...

Developing deep learning models on tiny devices (e.g. Microcontroller units, MCUs) has attracted much attention in various embedded IoT applications. However, it is challenging to efficiently design and deploy recent advanced models (e.g. transformers) on tiny devices due to their severe hardware resource constraints. In this work, we propose TinyFormer, a framework specifically designed to develop and deploy resource-efficient transformers on MCUs. TinyFormer mainly consists of SuperNAS, SparseNAS and SparseEngine. Separately, SuperNAS aims to search for an appropriate supernet from a vast search space. SparseNAS evaluates the best sparse single-path model including transformer architecture from the identified supernet. Finally, SparseEngine efficiently deploys the searched sparse models onto MCUs. To the best of our knowledge, SparseEngine is the first deployment framework capable of performing inference of sparse models with transformer on MCUs. Evaluation results on the CIFAR-10 dataset demonstrate that TinyFormer can develop efficient transformers with an accuracy of $96.1\%$ while adhering to hardware constraints of $1$MB storage and $320$KB memory. Additionally, TinyFormer achieves significant speedups in sparse inference, up to $12.2\times$, when compared to the CMSIS-NN library. TinyFormer is believed to bring powerful transformers into TinyML scenarios and greatly expand the scope of deep learning applications., Comment: This work has been submitted to the IEEE for possible publication more...

Autonomous vehicles are exposed to various weather during operation, which is likely to trigger the performance limitations of the perception system, leading to the safety of the intended functionality (SOTIF) problems. To efficiently generate data for testing the performance of visual perception algorithms under various weather conditions, a hierarchical-level rain image generative model, rain conditional CycleGAN (RCCycleGAN), is constructed. RCCycleGAN is based on the generative adversarial network (GAN) and can generate images of light, medium, and heavy rain. Different rain intensities are introduced as labels in conditional GAN (CGAN). Meanwhile, the model structure is optimized and the training strategy is adjusted to alleviate the problem of mode collapse. In addition, natural rain images of different intensities are collected and processed for model training and validation. Compared with the two baseline models, CycleGAN and DerainCycleGAN, the peak signal-to-noise ratio (PSNR) of RCCycleGAN on the test dataset is improved by 2.58 dB and 0.74 dB, and the structural similarity (SSIM) is improved by 18% and 8%, respectively. The ablation experiments are also carried out to validate the effectiveness of the model tuning. more...

Building scalable vision-language models to learn from diverse, multimodal data remains an open challenge. In this paper, we introduce an Efficient Vision-languagE foundation model, namely EVE, which is one unified multimodal Transformer pre-trained solely by one unified pre-training task. Specifically, EVE encodes both vision and language within a shared Transformer network integrated with modality-aware sparse Mixture-of-Experts (MoE) modules, which capture modality-specific information by selectively switching to different experts. To unify pre-training tasks of vision and language, EVE performs masked signal modeling on image-text pairs to reconstruct masked signals, i.e., image pixels and text tokens, given visible signals. This simple yet effective pre-training objective accelerates training by 3.5x compared to the model pre-trained with Image-Text Contrastive and Image-Text Matching losses. Owing to the combination of the unified architecture and pre-training task, EVE is easy to scale up, enabling better downstream performance with fewer resources and faster training speed. Despite its simplicity, EVE achieves state-of-the-art performance on various vision-language downstream tasks, including visual question answering, visual reasoning, and image-text retrieval., Comment: Accepted by AAAI 2024 more...

Interaction between the background vehicles (BVs) and automated vehicles (AVs) in scenario-based testing plays a critical role in evaluating the intelligence of the AVs. Current testing scenarios typically employ predefined or scripted BVs, which inadequately reflect the complexity of human-like social behaviors in real-world driving scenarios, and also lack a systematic metric for evaluating the comprehensive intelligence of AVs. Therefore, this paper proposes an evolving scenario generation method that utilizes deep reinforcement learning (DRL) to create human-like BVs for testing and intelligence evaluation of AVs. Firstly, a class of driver models with human-like competitive, cooperative, and mutual driving motivations is designed. Then, utilizing an improved "level-k" training procedure, the three distinct driver models acquire game-based interactive driving policies. And these models are assigned to BVs for generating evolving scenarios in which all BVs can interact continuously and evolve diverse contents. Next, a framework including safety, driving efficiency, and interaction utility are presented to evaluate and quantify the intelligence performance of 3 systems under test (SUTs), indicating the effectiveness of the evolving scenario for intelligence testing. Finally, the complexity and fidelity of the proposed evolving testing scenario are validated. The results demonstrate that the proposed evolving scenario exhibits the highest level of complexity compared to other baseline scenarios and has more than 85% similarity to naturalistic driving data. This highlights the potential of the proposed method to facilitate the development and evaluation of high-level AVs in a realistic and challenging environment., Comment: 18 pages,17 figures more...

We propose a PiggyBack, a Visual Question Answering platform that allows users to apply the state-of-the-art visual-language pretrained models easily. The PiggyBack supports the full stack of visual question answering tasks, specifically data processing, model fine-tuning, and result visualisation. We integrate visual-language models, pretrained by HuggingFace, an open-source API platform of deep learning technologies; however, it cannot be runnable without programming skills or deep learning understanding. Hence, our PiggyBack supports an easy-to-use browser-based user interface with several deep learning visual language pretrained models for general users and domain experts. The PiggyBack includes the following benefits: Free availability under the MIT License, Portability due to web-based and thus runs on almost any platform, A comprehensive data creation and processing technique, and ease of use on deep learning-based visual language pretrained models. The demo video is available on YouTube and can be found at https://youtu.be/iz44RZ1lF4s., Comment: Accepted by WSDM 2023 more...

The autonomous vehicle (AV) is a safety-critical system relying on complex sensors and algorithms. The AV may confront risk conditions if these sensors and algorithms misunderstand the environment and situation, even though all components are fault-free. The ISO 21448 defined the safety of the intended functionality (SOTIF), aiming to enhance the AV's safety by specifying AV's development and validation process. As required in the ISO 21448, the triggering conditions, which may lead to the vehicle's functional insufficiencies, should be analyzed and verified. However, there is not yet a method to realize a comprehensive and systematic identification of triggering conditions so far. This paper proposed an analysis framework of triggering conditions for the perception system based on the propagation chain of events model, which consists of triggering source, influenced perception stage, and triggering effect. According to the analysis framework, ontologies of triggering source and perception stage were constructed, and the relationships between concepts in ontologies are defined. According to these ontologies, triggering conditions can be generated comprehensively and systematically. The proposed method was applied on an L3 autonomous vehicle, and 20 from 87 triggering conditions identified were tested in the field, among which eight triggering conditions triggered risky behaviors of the vehicle., Comment: 12 pages,10 figures more...

Black-box functions are broadly used to model complex problems that provide no explicit information but the input and output. Despite existing studies of black-box function optimization, the solution set satisfying an inequality with a black-box function plays a more significant role than only one optimum in many practical situations. Covering as much as possible of the solution set through limited evaluations to the black-box objective function is defined as the Black-Box Coverage (BBC) problem in this paper. We formalized this problem in a sample-based search paradigm and constructed a coverage criterion with Confusion Matrix Analysis. Further, we propose LAMBDA (Latent-Action Monte-Carlo Beam Search with Density Adaption) to solve BBC problems. LAMBDA can focus around the solution set quickly by recursively partitioning the search space into accepted and rejected sub-spaces. Compared with La-MCTS, LAMBDA introduces density information to overcome the sampling bias of optimization and obtain more exploration. Benchmarking shows, LAMBDA achieved state-of-the-art performance among all baselines and was at most 33x faster to get 95% coverage than Random Search. Experiments also demonstrate that LAMBDA has a promising future in the verification of autonomous systems in virtual tests. more...

Presently 4T-1 luc cells were irradiated with proton under ultra-high dose rate FLASH or with gamma-ray with conventional dose rate, and then subcutaneous vaccination with or without Mn immuno-enhancing adjuvant into the mice for three times. One week later, we injected untreated 4T-1 luc cells on the other side of the vaccinated mice, and found that the untreated 4T-1 luc cells injected later nearly totally did not grow tumor (1/17) while controls without previous vaccination all grow tumors (18/18). The result is very interesting and the findings may help to explore in situ tumor vaccination as well as new combined radiotherapy strategies to effectively ablate primary and disseminated tumors. To our limited knowledge, this is the first paper reporting the high efficiency induction of systemic vaccination suppressing the metastasized/disseminated tumor progression., Comment: 16 pages, 3 figures and 1 table more...

In the era of big data astronomy, next generation telescopes and large sky surveys produce data sets at the TB or even PB level. Due to their large data volumes, these astronomical data sets are extremely difficult to transfer and analyze using personal computers or small clusters. In order to offer better access to data, data centers now generally provide online science platforms that enable analysis close to the data. The Chinese Virtual Observatory (China-VO) is one of the member projects in the International Virtual Observatory Alliance and it is dedicated to providing a research and education environment where globally distributed astronomy archives are simple to find, access, and interoperate. In this study, we summarize highlights of the work conducted at the China-VO, as well the experiences and lessons learned during the full life-cycle management of astronomical data. Finally, We discuss the challenges and future trends for astronomical science platforms., Comment: 26 pages,5 figure,accepted for publication in Astronomy and Computing more...