15 results on '"Bernaola, G."'
Search Results
2. Analizando la cinética de las remagnetizaciones por enterramiento. El caso de la Cuenca turbidítica de Jaca (Pirineos occidentales)
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Calvín, P., Pueyo, E. L., Larrasoaña, Juan C., Egli, R., Rodríguez Pintó, Adriana, Izquierdo Llavall, Esther, Oliva-Urcia, Belén, Beamud, Elisabet, Payros, Aitor, Mata Campo, Maria Pilar, Bellido Martín, Eva, Orera, A., Luzón, A., Gil Peña, Inmaculada, Bernaola, G., Montes, M., Samsó, Josep Maria, and Toro, R.
- Subjects
Cuenca de Jaca-Pamplona ,Diagénesis ,Remagnetización química - Abstract
X Congreso Geológico de España, 5-7 Julio 2021, Vitoria - Gasteiz, Las remagnetizaciones químicas regionales relacionadas con procesos de enterramiento y diagénesis son un proceso ampliamente extendido en cuñas orogénicas y cuencas sedimentarias. Este proceso conlleva la neoformación autigénica de minerales ferromagnéticos s.l. en relación con el aumento de temperatura asociado al enterramiento. Sin embargo, todavía no se conoce bien la cinética de estos procesos, debido en parte a que la mayoría de las remagnetizaciones de este tipo descritas en la literatura científica se produjeron durante supercrones magnéticos. Los materiales turbidíticos eocenos de la Cuenca de Jaca (Pirineos Occidentales) muestran una remagnetización química de doble polaridad, registrando varios crones a lo largo de la secuencia sedimentaria remagnetizada. Dentro del proyecto UKRIA4D (PID2019-104693GB-I00/CTA), se va a realizar un estudio multidisciplinar para relacionar temperatura de enterramiento, mineralogía magnética y edad de la remagnetización con la que evaluar de manera empírica las relaciones cinéticas entre los distintos factores.
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- 2021
3. The Bartonian-Priabonian marine record of the eastern South Pyrenean foreland basin (NE Spain): a new calibration of the larger foraminifers and calcareous nannofossil biozonation
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Costa, E., Garces, M., Lopez-Blanco, M., Serra-Kiel, J., Bernaola, G., Cabrera, L., and Beamud, E.
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- 2013
- Full Text
- View/download PDF
4. Paleocene larger foraminifera from the Pyrenean basin with a recalibration of the Paleocene Shallow Benthic Zones
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Consorci del Museu de Ciències Naturals de Barcelona, Serra-Kiel, Josep, Vicedo, Vicent, Baceta, J.I., Bernaola, G., and Robador, A.
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Ciència i tecnologia ,articles ,Foraminífers fòssils ,Bioestratigrafia ,Paleocè - Abstract
A taxonomic study of the larger foraminifera found in Paleocene rocks from the Pyrenean basin has led to the description of sixty taxa including two new species: Alveolina korresensis and Valvulineria bacetai. In this work, we present a chronostratigraphic recalibration of the Paleocene Shallow Benthic Zones (SBZ 1 to SBZ 4) based on correlation with calcareous nannofossil and planktic foraminifera biozones, all integrated within the stratigraphic framework of Paleocene platform to basin depositional sequences established for the whole Pyrenean domain. The samples were collected in autochtonous and parautochtonous deposits from ten key shallow platform stratigraphic sections, representative from coastal to platform margin depositional settings. The results from two base of slope sections with numerous intercalations of calcareous turbidites with penecontemporaneous platform-derived biota have been integrated in the study. The regional chronostratigraphic framework is derived from magneto-biochronological studies carried out in the Zumaia section, global reference section for the Danian-Selandian and Selandian-Thanertian GSSPs. The new calibration of the Paleocene SBZs is summarized as follows. The SBZ 1 is constrained to the first 1.09 m.y. of the Paleocene; this first Paleogene biozone lacks distinct larger foraminifera biomarkers and thus is defined by an association of non-exclusive taxa composed of Valvulineria patalaensis, Stomatorbina? binkhorsti, P.? antiqua and Bangiana hanseni. The SBZ 2 now appears as the biozone encompassing most of the Danian stage (from ca. 64.91 m.y. to 61.6 m.y.), and is characterized by the association of Haymanella elongata, Haymanella paleocenica, Kayseriella decastroi, Rotospirella conica, Pyrenerotalia depressa, Elazigina dienii and Paralockhartia eos. The SBZ 2-SBZ 3 boundary coincides with the base of the Selandian stage (ca. 61.6 m.y.). The SBZ 3 biozone is defined by Glomalveolina primaeva, Periloculina slovenica, Vania anatolica, Coskinon rajkae, Fallotella alavensis, Cribrobulimina carniolica, Miscellanea yvettae, Miscellanea juliettae, Miscellanites primitivus, Miscellanites minutus, Ranikothalia soldadensis, Nummulites heberti and Discocyclina seunesi. The SBZ 3-SBZ 4 boundary is now ascribed to ca. 57.2 m.y. The SBZ 4 biozone appears characterized by Glomalveolina levis, Alveolina korresensis, Hottingerina lukasi, Daviesina garumnensis, Assilina yvettae, Assilina azilensis and Nummulites catari. The SBZ 4-SBZ 5 boundary is placed at the Paleocene-Eocene boundary event (ca. 56.0 m.y.). A taxonomic study of the larger foraminifera found in Paleocene rocks from the Pyrenean basin has led to the description of sixty taxa including two new species: Alveolina korresensis and Valvulineria bacetai. In this work, we present a chronostratigraphic recalibration of the Paleocene Shallow Benthic Zones (SBZ 1 to SBZ 4) based on correlation with calcareous nannofossil and planktic foraminifera biozones, all integrated within the stratigraphic framework of Paleocene platform to basin depositional sequences established for the whole Pyrenean domain. The samples were collected in autochtonous and parautochtonous deposits from ten key shallow platform stratigraphic sections, representative from coastal to platform margin depositional settings. The results from two base of slope sections with numerous intercalations of calcareous turbidites with penecontemporaneous platform-derived biota have been integrated in the study. The regional chronostratigraphic framework is derived from magneto-biochronological studies carried out in the Zumaia section, global reference section for the Danian-Selandian and Selandian-Thanertian GSSPs. The new calibration of the Paleocene SBZs is summarized as follows. The SBZ 1 is constrained to the first 1.09 m.y. of the Paleocene; this first Paleogene biozone lacks distinct larger foraminifera biomarkers and thus is defined by an association of non-exclusive taxa composed of Valvulineria patalaensis, Stomatorbina? binkhorsti, P.? antiqua and Bangiana hanseni. The SBZ 2 now appears as the biozone encompassing most of the Danian stage (from ca. 64.91 m.y. to 61.6 m.y.), and is characterized by the association of Haymanella elongata, Haymanella paleocenica, Kayseriella decastroi, Rotospirella conica, Pyrenerotalia depressa, Elazigina dienii and Paralockhartia eos. The SBZ 2-SBZ 3 boundary coincides with the base of the Selandian stage (ca. 61.6 m.y.). The SBZ 3 biozone is defined by Glomalveolina primaeva, Periloculina slovenica, Vania anatolica, Coskinon rajkae, Fallotella alavensis, Cribrobulimina carniolica, Miscellanea yvettae, Miscellanea juliettae, Miscellanites primitivus, Miscellanites minutus, Ranikothalia soldadensis, Nummulites heberti and Discocyclina seunesi. The SBZ 3-SBZ 4 boundary is now ascribed to ca. 57.2 m.y. The SBZ 4 biozone appears characterized by Glomalveolina levis, Alveolina korresensis, Hottingerina lukasi, Daviesina garumnensis, Assilina yvettae, Assilina azilensis and Nummulites catari. The SBZ 4-SBZ 5 boundary is placed at the Paleocene-Eocene boundary event (ca. 56.0 m.y.). A taxonomic study of the larger foraminifera found in Paleocene rocks from the Pyrenean basin has led to the description of sixty taxa including two new species: Alveolina korresensis and Valvulineria bacetai. In this work, we present a chronostratigraphic recalibration of the Paleocene Shallow Benthic Zones (SBZ 1 to SBZ 4) based on correlation with calcareous nannofossil and planktic foraminifera biozones, all integrated within the stratigraphic framework of Paleocene platform to basin depositional sequences established for the whole Pyrenean domain. The samples were collected in autochtonous and parautochtonous deposits from ten key shallow platform stratigraphic sections, representative from coastal to platform margin depositional settings. The results from two base of slope sections with numerous intercalations of calcareous turbidites with penecontemporaneous platform-derived biota have been integrated in the study. The regional chronostratigraphic framework is derived from magneto-biochronological studies carried out in the Zumaia section, global reference section for the Danian-Selandian and Selandian-Thanertian GSSPs. The new calibration of the Paleocene SBZs is summarized as follows. The SBZ 1 is constrained to the first 1.09 m.y. of the Paleocene; this first Paleogene biozone lacks distinct larger foraminifera biomarkers and thus is defined by an association of non-exclusive taxa composed of Valvulineria patalaensis, Stomatorbina? binkhorsti, P.? antiqua and Bangiana hanseni. The SBZ 2 now appears as the biozone encompassing most of the Danian stage (from ca. 64.91 m.y. to 61.6 m.y.), and is characterized by the association of Haymanella elongata, Haymanella paleocenica, Kayseriella decastroi, Rotospirella conica, Pyrenerotalia depressa, Elazigina dienii and Paralockhartia eos. The SBZ 2-SBZ 3 boundary coincides with the base of the Selandian stage (ca. 61.6 m.y.). The SBZ 3 biozone is defined by Glomalveolina primaeva, Periloculina slovenica, Vania anatolica, Coskinon rajkae, Fallotella alavensis, Cribrobulimina carniolica, Miscellanea yvettae, Miscellanea juliettae, Miscellanites primitivus, Miscellanites minutus, Ranikothalia soldadensis, Nummulites heberti and Discocyclina seunesi. The SBZ 3-SBZ 4 boundary is now ascribed to ca. 57.2 m.y. The SBZ 4 biozone appears characterized by Glomalveolina levis, Alveolina korresensis, Hottingerina lukasi, Daviesina garumnensis, Assilina yvettae, Assilina azilensis and Nummulites catari. The SBZ 4-SBZ 5 boundary is placed at the Paleocene-Eocene boundary event (ca. 56.0 m.y.).
- Published
- 2020
5. Evaluación de la atención farmacéutica y del envío domiciliario de medicación a pacientes con leucemia mieloide crónica: proyecto TICAFAN
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San José Ruiz,B, Gil Lemus,MA, Ros Bernaola,G, Iglesias Pérez,AM, and De Miguel Cascon,M
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atención centrada en el paciente ,atención farmacéutica ,Leucemia mieloide crónica ,adherencia al tratamiento ,BCR-ABL ,telemedicina - Abstract
RESUMEN Objetivo: Describir y analizar los resultados obtenidos con el desarrollo del proyecto “Tecnologías de la Información y la Comunicación adaptadas a la Atención Farmacéutica No presencial” (TICAFAN). Confirmar la validez del modelo para prestar atención farmacéutica a pacientes con leucemia mieloide crónica. Método: Estudio antes-después del cambio en el modelo de dispensación y de atención farmacéutica. Se analizó la evolución de la enfermedad, las intervenciones farmacéuticas, la adherencia al tratamiento, el número de dispensaciones realizadas mediante envío domiciliario y sus incidentes desde el 1 de febrero del 2014 al 31 de octubre del 2016. En mayo del 2015 se realizó una encuesta de satisfacción. Resultados: Se incluyeron 21 pacientes en el programa, la edad media en el momento de inclusión fue de 55 años (DE 17). Se realizaron 470 envíos, con una disminución del 80% (DE 15) en los desplazamientos de los pacientes al hospital. Hubo 2 incidentes, por olvido de los pacientes del día del envío. Se registraron 49 intervenciones farmacéuticas y se atendieron 30 consultas a demanda fuera de las programadas, lo que supuso un mayor número de intervenciones que en el periodo anterior. No hubo diferencias en la adherencia antes y después de la inclusión en el programa. La respuesta se mantuvo en 9 pacientes, mejoró en otros 9 y empeoró en 3, recuperándose posteriormente. La satisfacción de los pacientes con el proyecto fue de 9,7 (DE 0,6) sobre 10. Conclusiones: El proyecto TICAFAN ha conseguido mantener la atención farmacéutica a los pacientes incluidos en el mismo, la adherencia y la respuesta al tratamiento, evitando desplazamientos al hospital para la dispensación de medicación.
- Published
- 2020
6. Heterogeneity in Allergy to Mollusks: A Clinical-Immunological Study in a Population From the North of Spain
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Azofra, J, primary, Echechipía, S, additional, Irazábal, B, additional, Muñoz, D, additional, Bernedo, N, additional, García, BE, additional, Gastaminza, G, additional, Goikoetxea, MJ, additional, Joral, A, additional, Lasa, E, additional, Gamboa, P, additional, Díaz, C, additional, Beristain, A, additional, Quiñones, D, additional, Bernaola, G, additional, Echenagusia, MA, additional, Liarte, I, additional, García, E, additional, Cuesta, J, additional, Martínez, MD, additional, Velasco, M, additional, Longo, N, additional, and Pastor-Vargas, C, additional
- Published
- 2017
- Full Text
- View/download PDF
7. DI-068 Chromatopsia and night blindness in a patient on capecitabine and temozolomide
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Bernaola, G Ros, primary, Gorordo, A De Basagoiti, additional, Foronda, A Belaustegui, additional, Garcia, S Mendiola, additional, Gimenez, LR Lopez, additional, and Ruiz, B San Jose, additional
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- 2016
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8. The Global Stratotype Sections and Points for the bases of the Selandian (Middle Paleocene) and Thanetian (Upper Paleocene) stages at Zumaia, Spain
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Schmitz, B., Pujalte, V., Eustoquio, M., Monechi, S., Orue-Etxebarria, X, Speijer, R.P., Alegret, L., Apellaniz, E., Arenillas, I., Aubry, M.P., Baceta, J.I., Berggren, W.A., Bernaola, G., Caballero, F., Clemmensen, A, Dinarès-Turell, J., Dupuis, C., Heilmann-Clausen, C., Hilario Orús, A., Knox, R., Martín-Rubio, M., Ortiz, S., Payros, A., Petrizzo, M.R., Sprong, J., Steurbaut, E., and Thomsen, E.
- Abstract
The global stratotype sections and points for the bases of the Selandian (Middle Paleocene) and Thanetian (Upper Paleocene) stages have been defined in the coastal cliff along the Itzurun Beach at the town of Zumaia in the Basque Country, northern Spain. In the hemipelagic section exposed at Zumaia the base of the Selandian Stage has been placed at the base of the Itzurun Formation, ca. 49 m above the Cretaceous/ Paleogene boundary. At the base of the Selandian, marls replace the succession of Danian red limestone and limestone-marl couplets. The best marine, global correlation criterion for the basal Selandian is the second radiation of the important calcareous nannofossil group, the fasciculiths. Species such as Fasciculithus ulii, F. billii, F. janii, F. involutus, F.pileatus and F. tympaniformis have their first appearance in the interval from a few decimetres below up to 1.1 m above the base of the Selandian. The marker species for nannofossil Zone NP5, F. tympaniformis, first occurs 1.1 m above the base. Excellent cyclostratigraphy and magnetostratigraphy in the section creates further correlation potential, with the base of the Selandian occuring 30 precession cycles (630 kyr) above the top of magnetochron C27n. Profound changes in sedimentology related to a major sea-level fall characterize the Danian-Selandian transition in sections along the margins of the North Atlantic. The base of the Thanetian Stage is placed in the same section ca. 78 m above the Cretaceous/Paleogene boundary. It is defined at a level 2.8 m or eight precession cycles above the base of the core of the distinct clay-rich interval associated with the Mid-Paleocene Biotic Event, and it corresponds to the base of magnetochron C26n in the section. The base of the Thanetian is not associated with any significant change in marine micro-fauna or flora. The calcareous nannofossil Zone NP6, marked by the first occurrence of Heliolithus kleinpelli starts ca. 6.5 m below the base of the Thanetian. The definitions of the global stratotype points for the bases of the Selandian and Thanetian stages are in good agreements with the definitions in the historical stratotype sections in Denmark and England, respectively.
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- 2011
9. New high resolution calcareous nannofossil analysis across the Danian/Selandian transition at the Zumaia section : comparison with South Tethys and Danish sections
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Bernaola, G., Martín-Rubio, M., and Baceta, J.I.
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Danian/Selandian ,Biostratigraphy ,Calcareous nannofossil ,Zumaia section - Abstract
A high resolution calcareous nannofossil biostratigraphic analysis was carried out across the Danian/Selandian transition at the Zumaia section (western Pyrenees). In the studied interval, spanning Varol's Subzone NTp7a to Zone NTp9, a sequence of 10 distinct calcareous nannofossil events is identified. The recognition of these bioevents confirms the continuous and expanded character of the Zumaia section and allows an accurate biostratigraphic correlation of the D/S transition between Zumaia, the Danish reference sections and the more southerly Tethys sections. According to this correlation, the abrupt transition from the upper Danian limestones (the calcisiltite unit) to the Lellinge Greensand that marks the D/S boundary in the type area correlates with the lithological change from the Aitzgorri Limestone Formation to the Itzurun Formation in Zumaia. The calcareous nannofossil bioevents recorded in connection with the organic-rich layer used to mark the base of the Selandian in the Tethys region were detected in Zumaia ~10 m below the top of the Aitzgorri Limestone Formation. This finding suggests that the organic-rich layer is considerably older than the Danian/Selandian (D/S) boundary at Zumaia and the type area, and thus using it to mark the D/S boundary in Tethys is not appropriate. According to a counting of limestone/marl couplets, which are demonstrated to be the stratigraphic expression of precession cycles throughout the Zumaia section, the organic-rich layer in the Tethys region is ~546 kyr older than the D/S boundary at the type area.
- Published
- 2009
10. Basin architecture and growth folding of the NW Zagros early foreland basin during the Late Cretaceous and early Tertiary
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Saura, Eduard, Vergés, Jaume, Homke, S., Blanc, E., Serra-Kiel, Josep, Bernaola, G., Casciello, Emilio, Fernández, Naiara, Romaire, I., Casini, Giulio, Embry, J. C., Sharp, I.R., Hunt, David W., Saura, Eduard, Vergés, Jaume, Homke, S., Blanc, E., Serra-Kiel, Josep, Bernaola, G., Casciello, Emilio, Fernández, Naiara, Romaire, I., Casini, Giulio, Embry, J. C., Sharp, I.R., and Hunt, David W.
- Abstract
We present and use the chronostratigraphy of 13 field logs and detailed mapping to constrain the evolution of the early Zagros foreland basin, in NW Iran. Large foraminifera, calcareous nannofossil, palynological and 87Sr/86Sr analysis supplied ages indicating a Campanian-early Eocene age of the basin infill, which is characterizd by a diachronous, southwestward migrating, shallowing upwards, mixed clastic- carbonate succession. Growth synclines and local palaeoslope variations indicate syndepositional folding from Maastrichtian to Eocene time and suggest forelandward migration of the deformation front. We also illustrate the basin architecture with a synthetic stratigraphic transect. From internal to external areas, time lines cross the formation boundaries from continental Kashkan red beds to Taleh Zang mixed clastic-carbonate platforms, Amiran slope deposits and basinal Gurpi-Pabdeh shales and marls. The foreland basin depocentres show a progressive migration from the Campanian to Eocene (c. 83-52.7 Ma), with rates of c. 2.4 mm a-1 during the early-middle Palaeocene (c. 65.5-58.7 Ma) increasing to c. 6 mm a-1 during the late Palaeocene- earliest Eocene (c. 58.7-52.8 Ma). Coeval subsidence remained at c. 0.27 mm a-1 during the first 12.7 Ma and decreased to c. 0.16 mm a-1 during the last 4.2 Ma of basin filling. Finally, we integrate our results with published large-scale maps and discuss their implications in the context of the Zagros orogeny. © 2011 Geological Society of London.
- Published
- 2011
11. Late Cretaceous-Paleocene formation of the proto-Zagros foreland basin, Lurestan Province, SW Iran
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Homke, S., Vergés, Jaume, Serra-Kiel, Josep, Bernaola, G., Sharp, Ian, Garcés, Miguel, Montero-Verdú, Ismael, Karpuz, Ridvan, Goodarzi, Mohammad Hassan, Homke, S., Vergés, Jaume, Serra-Kiel, Josep, Bernaola, G., Sharp, Ian, Garcés, Miguel, Montero-Verdú, Ismael, Karpuz, Ridvan, and Goodarzi, Mohammad Hassan
- Abstract
Late Cretaceous emplacement of ophiolitic-radiolaritic thrust sheets over the Arabian passive margin was the first manifestation of the protracted closure of the Neotethys Ocean, which ended with the continental collision between Arabia and central Iran and the formation of the present Zagros fold belt. This tectonic stacking produced a flexural basin (the Amiran Basin: 400 × 200 km in size) in the northwest Zagros that was filled with a 1225-m-thick shallowing-upward detrital succession made up of the Amiran, Taleh Zang, and Kashkan Formations. This succession sits unconformably above the Late Cretaceous Gurpi Formation and is overlain by the Oligocene-Miocene Shahbazan-Asmari carbonate succession. Dating of the Amiran-Kashkan succession is based on detailed biostratigraphy using large foraminifera and calcareous nannoplankton. The Cretaceous-Tertiary (K-T) boundary is located within the uppermost 25-45 m of the Gurpi Formation. The overlying Amiran and Taleh Zang Formations have been dated as Paleocene in age. However, the base of the Paleocene within the Gurpi Formation lacks NP1 and NP2 zones, implying a hiatus of ∼2 m.y. at ca. 65.5 Ma, which is inferred to correspond to an early folding phase near the Cretaceous-Paleocene boundary. The upper part of the Kashkan Formation is dated to the earliest Eocene by palynostratigraphy. A large hiatus (or very slow deposition) lasting about 15 m.y. occurs between the Kashkan and Shahbazan Formations in the studied region. The base of the prograding Shahbazan platform deposits is dated by 87Sr/86Sr stratigraphy at ca. 33.9 Ma. The upper part of the Asmari Formation is dated as early-middle Miocene using foraminifera associations. Reconstruction of the Amiran- Taleh Zang- Kashkan succession of the Amiran Basin indicates a thickening of the basin fill from the southern pinch-out along the SE flank of the Kabir Kuh anticline to SW of the Khorramabad anticline, where the flexure is at least 900 m. In contrast, the NE part of t
- Published
- 2009
12. THE PALEOCENE-EOCENE THERMAL MAXIMUM: NEW DATA ON MICROFOSSIL TURNOVER AT THE ZUMAIA SECTION, SPAIN
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ALEGRET, L., primary, ORTIZ, S., additional, ORUE-ETXEBARRIA, X., additional, BERNAOLA, G., additional, BACETA, J. I., additional, MONECHI, S., additional, APELLANIZ, E., additional, and PUJALTE, V., additional
- Published
- 2009
- Full Text
- View/download PDF
13. Heterogeneity in Allergy to Mollusks: A Clinical-Immunological Study in a Population From the North of Spain.
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Azofra J, Echechipía S, Irazábal B, Muñoz D, Bernedo N, García BE, Gastaminza G, Goikoetxea MJ, Joral A, Lasa E, Gamboa P, Díaz C, Beristain A, Quiñones D, Bernaola G, Echenagusia MA, Liarte I, García E, Cuesta J, Martínez MD, Velasco M, Longo N, and Pastor-Vargas C
- Subjects
- Humans, Animals, Spain epidemiology, Male, Female, Adult, Middle Aged, Prospective Studies, Adolescent, Immunoglobulin E immunology, Immunoglobulin E blood, Young Adult, Aged, Shellfish Hypersensitivity immunology, Skin Tests, Child, Food Hypersensitivity immunology, Food Hypersensitivity diagnosis, Food Hypersensitivity epidemiology, Mollusca immunology, Allergens immunology, Cross Reactions immunology
- Abstract
Background and Objective: Allergy to mollusks has been the focus of fewer studies than allergy to crustaceans. Furthermore, allergy to mollusks is less well characterized. Objectives: To describe the clinical characteristics of mollusk-allergic patients, to identify the responsible allergens, and to assess cross-reactivity., Methods: We performed a prospective multicenter study including 45 patients with mollusk allergy, which was diagnosed based on a suggestive clinical history and a positive skin test result with the agent involved. Fractions were identified using SDS-PAGE and immunoblotting. The proteins responsible were subsequently identified using mass spectrometry. ELISA inhibition studies were performed with mollusks, dust mites, and crustaceans., Results: We found that 25 patients (55%) were allergic to cephalopods, 14 (31%) to bivalves, and 11 (24%) to gastropods. Limpet was the third most frequent cause of allergy (15% of cases). In 31 patients (69%), the manifestation was systemic; 10 (22%) exhibited oral allergy syndrome, and 7 (15%) experienced contact urticaria. Most major allergens were found between 27 kDa and 47 kDa. ELISA inhibition assays revealed a high degree of inhibition of cephalopods and bivalves from all the groups of mollusks, mites, and crustaceans. Mass spectrometry identified tropomyosin, actin, and myosin as the major allergens., Conclusions: Cephalopods, especially squid, are the mollusks that most frequently trigger allergic symptoms. The very frequent occurrence of allergy to limpets is striking, given their low consumption in our area. It is worth highlighting the heterogeneity observed, exemplified by the gastropods. Tropomyosin appears to be responsible for the high cross-reactivity found between mollusks, mites, and crustaceans. Three new mollusk allergens were also identified, namely, actin, enolase, and a putative C1q domain-containing protein.
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- 2024
- Full Text
- View/download PDF
14. Description of patients with severe COVID-19 treated in a national referral hospital in Peru.
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Acosta G, Escobar G, Bernaola G, Alfaro J, Taype W, Marcos C, and Amado J
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- Adult, Aged, Aged, 80 and over, COVID-19, Coronavirus Infections mortality, Coronavirus Infections therapy, Cough epidemiology, Cough etiology, Dyspnea epidemiology, Dyspnea etiology, Female, Fever epidemiology, Fever etiology, Humans, Male, Middle Aged, Pandemics, Peru, Pneumonia, Viral mortality, Pneumonia, Viral therapy, Retrospective Studies, Risk Factors, Severity of Illness Index, Coronavirus Infections physiopathology, Hospitalization, Pneumonia, Viral physiopathology, Respiration, Artificial
- Abstract
In order to describe manifestations from patients with coronavirus disease 2019 (COVID-19), sociodemographic variables such as, previous medical history, clinical and radiological manifestations, treatments and evolution of patients were evaluated. This took place from March 6th to 25th, 2020, in the "Edgardo Rebagliati Martins" National Hospital in Lima. Seventeen patients were registered: 76% were male, with an average age of 53.5 years (range 25-94); 23.5% had returned from abroad; 41.2% were referred from other health facilities; 41.2% were admitted to mechanical ventilation; 29.4% (5 patients) died. The risk factors detected were: advanced age, arterial hypertension and obesity. The main symptoms detected were: cough, fever and dyspnea. Frequent laboratory findings were: elevated C-reactive protein and lymphopenia. The predominant radiological presentation was bilateral interstitial lung infiltrate. A first experience in the management of patients diagnosed with severe COVID-19 in Peru is reported.
- Published
- 2020
- Full Text
- View/download PDF
15. Sublingual immunotherapy: factors influencing adherence.
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Bernaola G, Corzo JL, Domínguez-Ortega J, Lucas C, Ojeda I, and Torres-Borrego J
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- Administration, Sublingual, Adult, Age Factors, Asthma immunology, Child, Follow-Up Studies, Humans, Immunotherapy, Active statistics & numerical data, Rhinitis, Allergic, Perennial immunology, Rhinitis, Allergic, Seasonal immunology, Surveys and Questionnaires, Allergens administration & dosage, Asthma therapy, Immunotherapy, Active methods, Patient Compliance statistics & numerical data, Rhinitis, Allergic, Perennial therapy, Rhinitis, Allergic, Seasonal therapy
- Published
- 2012
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