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1. Effect of viral storm in patients admitted to intensive care units with severe COVID-19 in Spain: a multicentre, prospective, cohort study

Author

Ortega, Alicia, de la Fuente, Amanda, Almansa, Raquel, Postigo, Tamara, Jorge, Noelia, Tedim, Ana P, González-González, Laura, Sánchez Recio, Lara, Trapiello, Wysali, Berezo, José Ángel, Herrán-Monge, Rubén, Blanco, Jesús, Enríquez, Pedro, Martínez, Isidoro, Martín-Vicente, María, Muñoz-Gómez, María José, Más, Vicente, Vázquez, Mónica, Cano, Olga, Martínez de la Gándara, Amalia, Rodríguez, Covadonga, Andrade, Gloria, Renedo, Gloria, Bustamante-Munguira, Juan, Cicuendez Ávila, Ramón, Salgado-Villén, María, Berruguilla-Pérez, Enrique, Güell, Estel, Casadiego Monachello, Fernando Javier, Recuerda Núñez, María, Sánchez Calvo, Juan Manuel, Peñasco-Martín, Yhivian, García Unzueta, María Teresa, Ceccato, Adrián, Fernández-Barat, Laia, Bouza Vieiro, María Teresa, Moreno-Romero, Ana, Pérez Bastida, Leire, del Río-Carbajo, Lorena, Albalá Martínez, Noelia, Gómez, José Manuel, Blasco, María Luisa, Caballero, Jesús, Barberà, Carme, González, Jessica, Nieto, María Teresa, Nieto-del Olmo, Jorge, Prol-Silva, Estefanía, Canseco-Ribas, Joan, Eiros, Jose María, Bermejo-Martin, Jesús F, García-Mateo, Nadia, Motos, Anna, Resino, Salvador, Tamayo, Luis, Ryan Murua, Pablo, Bustamante-Munguira, Elena, Gallego Curto, Elena, Úbeda-Iglesias, Alejandro, de la Torre, María del Carmen, Estella, Ángel, Campos-Fernández, Sandra, Martínez Varela, Ignacio, Pérez-García, Felipe, Socias, Lorenzo, López Messa, Juan, Vidal-Cortés, Pablo, Sagredo Meneses, Víctor, González-Rivera, Milagros, Carbonell, Nieves, de Gonzalo-Calvo, David, Martín Delgado, María Cruz, Valdivia, Luis Jorge, Martín-López, Caridad, Jorge García, Ruth Noemí, Maseda, Emilio, Loza-Vázquez, Ana, Kelvin, David J, Barbé, Ferrán, and Torres, Antoni

Published
2023
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2. Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Micheloud, Dariela, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Ryan Murua, Pablo, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Fernández Natal, Isabel, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, de la Fuente, Amanda, del Campo, Félix, Fernández-Ratero, José Antonio, Trapiello, Wysali, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, García Olivares, Pablo, Cedeño, Jamil Antonio, Ruiz Albi, Tomás, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Abadia, Jesica, Gómez Barquero, Julia, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Fernández Caso, Belén, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Barbé, Ferrán, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Published
2020
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3. Low anti‐SARS‐CoV‐2 S antibody levels predict increased mortality and dissemination of viral components in the blood of critical COVID‐19 patients

Author

Martin‐Vicente, María, primary, Almansa, Raquel, additional, Martínez, Isidoro, additional, Tedim, Ana P., additional, Bustamante, Elena, additional, Tamayo, Luis, additional, Aldecoa, César, additional, Gómez, José Manuel, additional, Renedo, Gloria, additional, Berezo, Jose Ángel, additional, Cedeño, Jamil Antonio, additional, Mamolar, Nuria, additional, García Olivares, Pablo, additional, Herrán‐Monge, Rubén, additional, Cicuendez, Ramón, additional, Enríquez, Pedro, additional, Ortega, Alicia, additional, Jorge, Noelia, additional, Doncel, Cristina, additional, de la Fuente, Amanda, additional, Bustamante‐Munguira, Juan, additional, Muñoz‐Gómez, María José, additional, González‐Rivera, Milagros, additional, Puertas, Carolina, additional, Más, Vicente, additional, Vázquez, Mónica, additional, Pérez‐García, Felipe, additional, Rico‐Feijoo, Jesús, additional, Martín, Silvia, additional, Motos, Anna, additional, Fernandez‐Barat, Laia, additional, Eiros, Jose María, additional, Dominguez‐Gil, Marta, additional, Ferrer, Ricard, additional, Barbé, Ferrán, additional, Trapiello, Wysali, additional, Kelvin, David J., additional, Bermejo‐Martin, Jesús F., additional, Resino, Salvador, additional, and Torres, Antoni, additional

Published
2021
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4. Low anti‐SARS‐CoV‐2 S antibody levels predict increased mortality and dissemination of viral components in the blood of critical COVID‐19 patients.

Author

Martin‐Vicente, María, Almansa, Raquel, Martínez, Isidoro, Tedim, Ana P., Bustamante, Elena, Tamayo, Luis, Aldecoa, César, Gómez, José Manuel, Renedo, Gloria, Berezo, Jose Ángel, Cedeño, Jamil Antonio, Mamolar, Nuria, García Olivares, Pablo, Herrán‐Monge, Rubén, Cicuendez, Ramón, Enríquez, Pedro, Ortega, Alicia, Jorge, Noelia, Doncel, Cristina, and de la Fuente, Amanda

Subjects
COVID-19, VIRAL antibodies, IMMUNOGLOBULINS, MORTALITY, VIRAL replication
Abstract

Background: Anti‐SARS‐CoV‐2 S antibodies prevent viral replication. Critically ill COVID‐19 patients show viral material in plasma, associated with a dysregulated host response. If these antibodies influence survival and viral dissemination in ICU‐COVID patients is unknown. Patients/Methods: We studied the impact of anti‐SARS‐CoV‐2 S antibodies levels on survival, viral RNA‐load in plasma, and N‐antigenaemia in 92 COVID‐19 patients over ICU admission. Results: Frequency of N‐antigenaemia was >2.5‐fold higher in absence of antibodies. Antibodies correlated inversely with viral RNA‐load in plasma, representing a protective factor against mortality (adjusted HR [CI 95%], p): (S IgM [AUC ≥ 60]: 0.44 [0.22; 0.88], 0.020); (S IgG [AUC ≥ 237]: 0.31 [0.16; 0.61], <0.001). Viral RNA‐load in plasma and N‐antigenaemia predicted increased mortality: (N1‐viral load [≥2.156 copies/ml]: 2.25 [1.16; 4.36], 0.016); (N‐antigenaemia: 2.45 [1.27; 4.69], 0.007). Conclusions: Low anti‐SARS‐CoV‐2 S antibody levels predict mortality in critical COVID‐19. Our findings support that these antibodies contribute to prevent systemic dissemination of SARS‐CoV‐2. [ABSTRACT FROM AUTHOR]

Published
2022
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5. Additional file 3 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Abstract

Additional file 3. Multivariate logistic regression analysis comparing outpatients against wards patients (backward stepwise selection method/Likelihood Ratio). The association between viral RNAemia with hospitalization at the wards was evaluated adjusting by major confounding factors, but it was not selected in the final model.

Published
2020
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7. Additional file 4 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Subjects
3. Good health
Abstract

Additional file 4. Multivariate logistic regression analysis comparing wards patients against ICU patients (backward stepwise selection method/Likelihood Ratio). The association between viral RNAemia and viral RNA load with critical illness was evaluated adjusting by major confounding factors.

8. Additional file 1 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Subjects
3. Good health
Abstract

Additional file 1. Recruited patients in each hospital.

9. Additional file 2 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Subjects
3. Good health
Abstract

Additional file 2. Multivariate logistic regression analysis comparing outpatients against wards patients (Enter method). The association between viral RNAemia with hospitalization at the wards was evaluated adjusting by major confounding factors.

10. Additional file 1 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Subjects
3. Good health
Abstract

Additional file 1. Recruited patients in each hospital.

11. Additional file 5 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Subjects
3. Good health
Abstract

Additional file 5. Laboratory parameters levels across groups.

12. Additional file 5 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Subjects
3. Good health
Abstract

Additional file 5. Laboratory parameters levels across groups.

13. Additional file 4 of Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

Author

Bermejo-Martin, Jesús F., González-Rivera, Milagros, Almansa, Raquel, Dariela Micheloud, Tedim, Ana P., Domínguez-Gil, Marta, Resino, Salvador, Martín-Fernández, Marta, Murua, Pablo Ryan, Pérez-García, Felipe, Tamayo, Luis, Lopez-Izquierdo, Raúl, Bustamante, Elena, Aldecoa, César, Gómez, José Manuel, Rico-Feijoo, Jesús, Orduña, Antonio, Méndez, Raúl, Natal, Isabel Fernández, Megías, Gregoria, González-Estecha, Montserrat, Carriedo, Demetrio, Doncel, Cristina, Jorge, Noelia, Ortega, Alicia, Fuente, Amanda De La, Campo, Félix Del, Fernández-Ratero, José Antonio, Wysali Trapiello, González-Jiménez, Paula, Ruiz, Guadalupe, Kelvin, Alyson A., Ostadgavahi, Ali Toloue, Oneizat, Ruth, Ruiz, Luz María, Miguéns, Iria, Gargallo, Esther, Muñoz, Ioana, Pelegrin, Sara, Martín, Silvia, Olivares, Pablo García, Cedeño, Jamil Antonio, Albi, Tomás Ruiz, Puertas, Carolina, Berezo, Jose Ángel, Renedo, Gloria, Herrán, Rubén, Bustamante-Munguira, Juan, Enríquez, Pedro, Cicuendez, Ramón, Blanco, Jesús, Jesica Abadia, Barquero, Julia Gómez, Mamolar, Nuria, Blanca-López, Natalia, Valdivia, Luis Jorge, Caso, Belén Fernández, Mantecón, María Ángeles, Motos, Anna, Fernandez-Barat, Laia, Ferrer, Ricard, Ferrán Barbé, Torres, Antoni, Menéndez, Rosario, Eiros, José María, and Kelvin, David J.

Subjects
3. Good health
Abstract

Additional file 4. Multivariate logistic regression analysis comparing wards patients against ICU patients (backward stepwise selection method/Likelihood Ratio). The association between viral RNAemia and viral RNA load with critical illness was evaluated adjusting by major confounding factors.

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