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Aims: To determine ultrasound therapy as an effective adjuvant for the management of myofascial pain involving masticatory muscles. Study Design: Randomized clinical trial study. Place and Duration of Study: Department of oral medicine and radiology, Narayana dental college and hospital between March 2021 to November 2022. Methodology: We included 30 patients (20 females and 10 males; age group >18 years) clinically diagnosed with Myofascial pain who were randomly assigned into two groups each comprising of 15 patients. Group A patients received ultrasound therapy along with tizanidine 2mg twice a day for 14 days while group B patients received tizanidine alone. All the patients were evaluated for maximum inter-incisal distance, tenderness of muscles of mastication on palpation, pain while chewing, and pain during mandibular movements at baseline, 7th and 14th day. Results: A significant pain reduction and improvement in mouth opening was found in both the groups. However, patients who received both tizanidine and ultrasound therapy had greater relief compared to other group from 7th day to 14th day and the results were statistically significant. Conclusion: No side effects were observed in Group A during or after ultrasound therapy. As it is a non-invasive therapeutic modality and offers good patient compliance, ultrasound therapy can be used as an effective therapeutic adjuvant for the management of myofascial pain.

Breast cancer (BC) disease is the most common and rapidly spreading disease across the globe. This disease can be prevented if identified early, and this eventually reduces the death rate. Machine learning (ML) is the most frequently utilized technology in research. Cancer patients can benefit from early detection and diagnosis. Using machine learning approaches, this research proposes an improved way of detecting breast cancer. To deal with the problem of imbalanced data in the class and noise, the Synthetic Minority Oversampling Technique (SMOTE) has been used. There are two steps in the suggested task. In the first phase, SMOTE is utilized to decrease the influence of imbalance data issues, and subsequently, in the next phase, data is classified using the Naive Bayes classifier, decision trees classifier, Random Forest, and their ensembles. According to the experimental analysis, the XGBoost-Random Forest ensemble classifier outperforms with 98.20% accuracy in the early detection of breast cancer.

Plants are sessile and sensitive organisms that inevitably encounter a variety of abiotic stresses in nature. Abiotic stresses such as salinity, drought, heavy metal toxicity and extreme temperatures are critical factors that reduce crop yields by more than 50% worldwide. Sustainable agriculture in harsh environments requires an understanding of the ways that crop plants respond to both biotic and abiotic factors. The aim of the study was to determine the influence of water stress and heavy metals (Cd and Cr) singly and in combination on germination and seedling growth of two Green gram (VignaradiataL.Wilzec) cultivars.Seeds of two Green gram (Vignaradiata L. Wilczek ) cv. ML – 267, TM 96-2 cultivars were subjected to water stress by using PEG – 6000 ( -0.3 MPa , -0.6 MPa , -0.9 MPa and -1.2 MPa); Cadmium and Chromium(20,60,100,200,400ppm). The seed germination percentage decreased significantly with increasing concentration of Cd and Cr. Decreased osmotic potential caused a decrease in germination percentage. In comparison with the control treatment, the lowest germination rate values determined at -0.9MPa, 400 ppm Cd and 400 ppm Cr. Shoot and root length was reduced significantly with a rise in PEG and heavy metal levels. Cd concentration had a more depressing effect on the root than on the shoot growth. Interactive effects between heavy metal and water stress on dry weight and root length was significant. According to this study the interactive effect of both stresses were however, less than additive. References Almansouri, M., Kinet, J.M., Lutts, S. 2001. Effect of salt and osmotic stresses on germination in durum wheat. Plant Soil. 231: 243-254. AOSA. 1990. Rules for Testing Seeds, USA. J Seed Technol 12:1-112. Cavusoglu, K. and Emine, Y. 2010. Detection of lipid peroxidation and cytotoxicity induced by aluminium and cobalt ions in barbunia root tip cells. J. Env.Biol. 31: 661-666. Gelmond, H. 1978. Problems in crop seed germination. In: U.S. Gupta (ed.), Crop Physiology, PP:1-78. Oxford and I.B.H. Publishing Co., New Delhi. Kaydan, D. and Yagmur, M. 2008. Germination, Seedling growth and relative water content of shoot in different seed sizes of triticale under osmotic stress of water and NaCl. Afr.J. Biotechnol. 7: 2862-2868. Lobato, A.K.S., Oliveira Neto, C.F., Costa, R.C.L., Santos Filho, B.G., Cruz, F.J.R. and Laughinghouse IV, H.D. 2008. Biochemical and physiological behavior of VignaUnguiculata (L.) Walp. Under water stress during the vegetative phase. Asian Journal of Plant Sciences. 7(1): 44-49. Misra, V. and S.D. Pandey, 2002. Effect of distillery effluent and leachates of industrial sludge on the germination of Black gram. Poll. Res. 21(4), 461-467. Michel, B.E. and Kaufmann, M.R. 1973. The osmotic potential of polyethylene glycol 6000. Plant Physiology 51, 914-916. Masoud Sinaki J., Ghorban Nour mohammadi and Abbas Maleki. 2004. Effect of Water Deficit on Seedling, Plantlets and Compatible Solutes of Forage Sorghum cv. SpeedfeedICSC. Retreived from www.cropscience.org.au/ icsc 2004 Munzuroglu, O and Zengin, F.K. 2006. Effect of Cadmium on germination, coleoptiles and root growth of barley seeds in presence of gibberellic acid and kinetin. J. Env.Biol. 27: 671-677.

With the development of more compact and powerful methods of designing a digital logic on a silicon chip, most of the signal processing is being implemented in the digital domain. The implementation of an efficient reconfigurable digital decimation filter is presented in the work. In this paper we focuses with the implementation and design of a decimation filter which is used for hearing aid applications. We design decimation filter with the help of the canonic signed digit (CSD) representation. In decimation filter the cascaded integrated comb filter is designed using without multiplier less. The half band and corrector filters are designed using CSD. The decimation filter has been implemented on Xilinx FPGA using Virtex-2 technology and number of slices ,number of LUTs and number of registers are reported and also proposed design is implemented in synopsis design compiler for ASIC implementation and calculated area, power and delay. The resulting architecture is hardware efficient and consumes less power compared to conventional decimation filters. Compared to the normal decimation filter architecture, the proposed decimation filter architecture has less hardware saving of 60% and in addition, it decreases the power consumption of 80%, respectively and the proposed architecture is well suited for decimation filters of the hearing aids.

Investigation on evaluation of sesame genotypes for their relative resistance against leaf webber and capsule borer, Antigastra catalaunalis (Crambidae: Lepidoptera) was conducted at RARS, Jagtial during summer, 2020. A total of 68 sesame genotypes including TKG-22 (resistance check) and Swetha thil (susceptible check) were evaluated for their relative resistance/susceptibility. The intensity of leaf damage at 30 DAS is ranged from 5.00% (FFAT-10-5) to 25.00% (FFAT-142) whereas the mean leaf damage, 2.20% and 22.00% was found in resistant (TKG 22) and susceptible checks (Swetha thil), respectively. The mean percent flower damage at 50 DAS was recorded between 5.50% (JCS 3886 and JCS 4120) to 22.50% (FFAT-142 and JCS-3899) as against 4.50% and 19.00% in resistant (TKG-22) and susceptible (Swetha thil) checks respectively. The average percent capsule damage at 70 DAS is ranged from 2.75% (SI-225) to 9.00% (JCS 3603, JCS 3596 and JCS 4096) whereas, the mean capsule damage of 3.00% and 9.50% was recorded in resistant (TKG-22) and susceptible (Swetha thil) checks respectively. The sesame genotypes were categorized as highly resistant (HR), resistant (R), moderately resistant (MR), susceptible (S) and highly susceptible (HS) based on the cumulative score (0-9) and grade (1-9) of the individual genotype. Among 68 genotypes a total of 10 genotypes viz., IC-14120-1, SI-225, Jagtiala til-1, JCS 3980, JCS 3981, JCS 4053, JCS 3886, JCS 4120, YLM 11 and YLM 66 were showed less susceptibility to A. catalaunalis. These germplasm lines might be exploited in hybridization programme for development of the resistant cultivars.

A series of 2-(naphthalen-1-yl)-methyl-6-arylimidazo[2,1-b][1,3,4]thiadiazole derivatives was prepared and studied for cytotoxicity against murine leukemia L1210, human cervix carcinoma HeLa, and human T-lymphocyte CEM cell lines. The preliminary study showed that compounds 5g, 6g, 7a-c, 7e, and 8e were more potent among the tested compounds. The pharmacokinetic properties of all compounds were then investigated with FAF-Drugs, a tool for prediction of ADME and toxicity. Finally, in order to support in vitro studies, molecular docking studies were performed by using AutoDock Vina with a Lamarckian genetic algorithm to determine whether or not the synthesized compounds could be used as inhibitors for the protein structure 1m17 (EGFR). The docking scores of many compounds were found to be higher than [6,7-bis(2-methoxy-ethoxy)quinazoline-4-yl]-(3-ethynyl phenyl)amine, an inhibitor of the 1m17 EGFR receptor. Among the selected compounds 7b, 7c, 7e, 7f, 7g, and 8g showed better stability in the molecular dynamics simulation study.

Background: Adolescence is a distinct phase of complex developmental and psychological needs. UNICEF states that suicide is the second leading cause of death in this age group of young girls. A myriad of social, economic and health factors undermine the ability of the adolescents to lead full and productive lives. There is a need to study these factors as they are bound to health-related outcomes. Objective: To assess the psycho-social health of adolescent girls (15-19 years) living in a rural area using WHO HEEADSSS questionnaire and to compare their psychosocial risk profiles and demographic profiles to identify important risk factors. Methodology: This cross-sectional study was conducted from April to August 2017 on a convenient sample of 180 adolescent girls of 15-19 years residing in the rural field practice area of NRI Medical College, Guntur. The WHO’s HEEADSSS (Home and Environment, Education and Employment, Activities, Drugs, Sexuality, Suicide & Depression and Safety) questionnaire was used to assess the psychosocial risk profile of the subjects. The findings were subjected to multiple regression and chi-square test at 5% level of significance. Results and Discussion: Only 6.11% of the girls had scores within the normal range. 10% were at severe risk and 1.11% were in the very severe risk category. The following factors accounted for 75% of the psycho social risk: Age, Marital Status, Occupation, Positive History of Smoking or Alcohol intake in Family, Having Sleep Problems, Thoughts of inflicting self-hurt and Thoughts of inflicting physical hurt on others. Conclusion: HEEADSSS questionnaire is a useful tool to assess the psycho-social health of adolescent girls. Most girls didn’t have adequate knowledge regarding family panning methods or STDs. Qualitative methods would give further insight into these issues.

The cutting forces that are generated during metal cutting influence the work piece precision, tool wear, the nature of the machined surface, and heat generation. These cutting forces can be measured analytically however; precise outcomes may not be expected due to its included stresses, parameters of cutting, and the perplexing tool geometry. Henceforth the exploratory estimation of cutting forces is fundamental. For this reason, a milling dynamometer of three-segment is structured, created, and tried to gauge the three cutting forces which are produced during the operation of milling strain gauges can be utilized to quantify dynamic and static cutting forces through milling dynamometer. During the process of metal cutting, a dynamometer that is based on strain gauge is fit for estimating three-force segments. The dynamometer was designed based on the octagonal ring principle. The octagonal rings orientation and location of strain gauges have resolved to expand affectability and to limit cross-affectability.

Background: Adolescence lays the foundation for physical wellbeing, emotional stability and mental ability. Quantitative methods often lack depth of understanding on crucial issues and leave many lacunae in the information available about the problems faced by adolescent girls in India. Using qualitative methods, a researcher can go beyond the surface and gather hidden information and associated feelings. Objective of the research was to qualitatively assess the knowledge, attitude and practices of health among adolescent girls (15-19 years) living in a rural area.Methods: This qualitative study to explore issues surrounding the health of adolescent girls in a rural area was conducted from August 2018 to November 2018 in the rural field practice area of the NRI Medical College. The qualitative methods used to gather information were focus group discussions (FGDs) and in-depth interviews (IDIs). Triangulation of information was done through key informant interviews (KIIs) with professionals working with adolescents.Results: The themes identified were causes of stress, education & marriage, safe pregnancy, prevalent diseases, exercise and leisure, health seeking behaviour and domestic violence. In-depth interviews with girls having significant social and psychological risk factors revealed a sense of loss of freedom, decision making power and resignation to their fate. Key informants revealed the neglect of adolescents in health programmes.Conclusions: Adolescent girls have poor knowledge about important health issues. Interventions that focus both on the continuation of the girls’ education and creating options for generating income are necessary along with non-judgmental counseling services and adolescent friendly health care facilities.

Digital picture watermarking is employed to stay secret the proprietary info as a watermark within a digital image, to spot the possession. This method has relevancy to any or all pictures. Separate trigonometric function transform (DCT) is employed before inserting the watermark within the host image. The host picture is isolated into 8×8 non-covering hinders preceding DCT application, and therefore the watermark bit is inserted by dynamic distinction between DCT coefficients of contiguous squares. Arnold transform is employed even so disorderly encoding to feature 2-fold block safeguard to the watermark. 3 distinctive variations of the planned calculation are tried and stone-broke down. The reenactment results demonstrate that the planned set up is powerful to the overwhelming majority of the image making ready tasks like JPEG pressure, honing, trimming, middle separating, and so on. To approve the proficiency of the planned technique, the recreation results are contrasted and sure condition of-workmanship systems. The examination results represent that the planned set up performs higher as so much as power, security and imperceptivity. Given the advantages of the planned set up, it alright could also be used in applications like e-social insurance and telemedicine to smartly hide out electronic eudemonia records in therapeutic footage.

Internet of Things has given a lot simpler answer for remote continuous wellbeing checking of patients from the clinic just as home. Sensors secure the information of different parameters in regards to patients’ wellbeing, and the Internet of Things stores that information and shows through the site, which gives access to remote observing. Utilization of Sensor decreases the human mistake, and the span of the framework lessens the involved space of the room. The extraordinary piece of this proposed arrangement is the alert age to give the recommended prescription to the patient in time. The other gainful zone of the framework is the plan of sending the warning through email and SMS alert if any of the wellbeing parameters crosses the limit esteem. Notice plan will keep the separate expert aware of the circumstance. Another huge region of the proposed arrangement is to make the ideal surroundings according to the necessity of patient’s wellbeing condition. In this paper, we have talked about the checking of pulse, circulatory strain, breath rate, body temperature, body development and saline dimensions.

Objectives: This study aimed to establish the pharmacognostic profile of aerial parts of Euphorbia tirucalli (ET) as per World Health Organization guidelines for ensuring the quality and identification of adulteration. Materials and Methods: Standardization parameters such as macroscopic and microscopic characteristics of the study plant were evaluated. Hydroalcoholic and ethyl acetate extracts were prepared and subjected to preliminary phytochemical screening. Further, the extracts were used to analyze total phenol and flavonoid contents, and their antioxidant activities were estimated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and nitric oxide assay. Results: Shape, size, color, odor, surface characteristics, and microscopic images exhibited useful diagnostic characteristics of aerial parts of plants. Total ash, water-soluble, and acid-insoluble ash were found to be 16.65' ± 1.050', 5.623' ± 1.11', and 2.56' ± 0.706, respectively. The loss on drying was 9.6', and water and alcoholic extractive values were 4.0' and 26', respectively. Phytochemical screening revealed the presence of saponins, steroidal triterpenoids, phenols, and flavonoids. Total flavanoid and phenol content in hydroalcoholic and ethyl acetate extracts of ET was found to be 246 mg rut/g, 120 mg rut/g, 81.36 mg gallic acid equivalent (GAE)/g, and 279.58 mg GAE/g respectively. 2,2-diphenyl-1-picrylhydrazyl and nitric oxide scavenging assay revealed the IC50 values of hydroalcoholic and ethyl acetate extracts as 69.599 μg/ml, 20.454 μg/ml, 17.017 μg/ml, and 17.562, respectively. Conclusion: The findings obtained from the present study help to authenticate and establish the pharmacopeia standards for the ET plant.

One of the primary worries with our condition has been garbage waste management which notwithstanding aggravating the parity of nature likewise effect sly affects the wellbeing of the general public. Detecting, monitoring and managing the squanders are one of the essential issues of the present time. The conventional method for physically checking the losses in waste receptacles is a mind boggling, unwieldy procedure and uses progressively human exertion, time and cost which isn’t perfect with the present day innovations in any capacity. This method is an automated garbage management system. This undertaking IoT Garbage Monitoring framework is an imaginative system which will keep the rural and urban areas clean. This framework screens the garbage bins and illuminates about the dimension of rubbish gathered in the junk canisters by means of a website page. This website page additionally sends all data to garbage collecting vehicles.

Cerebral hydatid disease is very rare, representing only 2% of all cerebral space occupying lesions even in the countries where the disease is endemic. Echinococcal cysts are usually found in the liver and lungs, but can affect any part of the body. Differential diagnosis of hydatid disease should be considered for every cystic mass in any anatomical location, especially in areas where the disease is endemic. Hydatid disease has a worldwide distribution and causes health problems in endemic countries. Here, we are presenting a case of cerebral hydatid cyst in a 7-year-old female child. The main aim of this case is to highlight the rarity of this location and that hydatid cysts must be considered as differential diagnosis in patients with cystic lesions of brain, especially in endemic areas.

Tuberculosis of parotid lymph nodes is a rare condition. Although uncommon, it must be included in differential diagnosis of a discrete parotid gland swelling or mass. Early recognition of the disease entity and awareness of its potential existence can spare the patient unnecessary surgical intervention. A 13-year-old female patient presented with a painless swelling in left preauricular region. Ultrasonographic examination showed presence of calcified lymph nodes with central necrosis. Fine needle aspiration cytology showed epitheloid cells, foci of calcification and areas of caseation necrosis suggestive of tuberculosis- Standard antituberculous regimen was planned for 6 months with rifampicin, ethambutol, isoniazid and pyrazinamide. Patient discontinued the antituberculous regimen after free of clinical symptoms at the end of the 5th month. Recurrence of the tuberculosis was seen 2 weeks after the discontinuation of the treatment. Completed retreatment for 8 months and follow-up shown patient free of tuberculosis.

Purpose: Proper care must be taken even for a clean wound in normal body to heal earlier with a minimum scar. Various scientific and technological advancement taking place from time to time the problem wound healing is still under evolution process, till now there are many research works have been undertaken on Chronic wounds. As Dustavrana is vitiated by various doshas so it needs proper care in proper time. Hence in present concept all efforts are directed to keep the wound clean and also to enhance the wound healing. To manage the Dustavrana different type of treatment modalities explained in the classics, Bala Taila is one among them. Objective of study: To assess the effectiveness of BalaTaila Application in wound healing. To assess the healing of wound (Vrana ropana). Method: 30 patients were selected according to inclusion criteria and divided into two groups of 15 each. Viz Group I: Trail group, were treated by Bala Taila local application once daily & Group II: Control group, were treated by the application of Hydrogen Peroxyde, sterile dry gauze were used for dressing. Result: Results were assessed with the help of prefixed assessment criteria, and favorable results obtained on, Vedana as 85%, Swelling 80%, Varna 84.44%, Srava 82.92% Granulation 86.66% and size of wound 79.41%. The result of Bala Taila is found to be statically significant in the process of wound healing Conclusion: The Bala Taila proves a vital role in the healing of Dustavrana.