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Introduction: The problem of infertility is experienced as a crisis or major life stressor with potentially serious negative effects on the couple's relationship and preparation toward the parenthood. According to Sharlip et al., it has been estimated that about 15% of couple would have trouble in conception, and at present, 48.5 million couples experience infertility globally. To decrease the stress among parents to be and to promote healthy parenting for bringing out healthy parent–child relationships, an intervention of Parent Education Program was planned and executed. A study was conducted with the aim to assess the effectiveness of parental preparedness package (PPP) on physical health among couple conceived with artificial reproductive techniques (ART). Materials and Methods: The study was conducted to evaluate the effectiveness of PPP in fifty couples conceived with ART at Dayanand Medical College and Hospital, Ludhiana. Quantitative approach was used to collect the data of couples by doing pre- and postinterventional assessment of physical health of couple using the Structured Physical Health Assessment Scale. Analysis was done with the help of descriptive and inferential statistics. Results: The study revealed that mean score of physical health of couple (both husband and wife) increased significantly after the intervention which infers the effectiveness of PPP (P = 0.001). Conclusion: Our study concludes that PPP should be incorporated in the antenatal care protocol in all couples who conceive using ART. [ABSTRACT FROM AUTHOR]

Sickle cell disease (SCD) is a known risk factor for the development of severe dengue, however, literature documenting dengue in SCD is scarce. Dengue fever further triggers the sickling process in a patient with SCD by augmenting endothelial dysfunction, the main identifiable cause behind organ dysfunction. Hepatic involvement in SCD due to enhanced sickling can be in the form of acute viral hepatitis, cholecystitis, acute sickle hepatic crisis, and more severe sickle cell intrahepatic cholestasis (SCIC). Initially starting as an acute sickle hepatic crisis, SCIC progresses to striking jaundice, enhanced bleeding tendency coupled with mostly renal failure. We report a rare case of a female, native of Chhattisgarh with SCD and dengue shock syndrome who had fatal hepatic complications resulting from accelerated severe endothelial dysfunction due to concurrent illnesses. [ABSTRACT FROM AUTHOR]

The Luxury Goods Industry is going through a drastic revolution as both clothing manufacturers and consumers have been acclimatizing to a rather new way of interaction. Manufacturers are shifting their approach towards integrating innovation into their longstanding research development and product development aligning them with consumers’ demands across the globe. This paper aims at studying innovation solutions, in the form of a case study, adopted by iconic French Luxury brand Louis Vuitton (LV), which is focused on delivering luxury shopping experiences using state-of-the-art 3D Printing technology which has been emerging tremendously. 3D-printing is a popular scientific technology for creation of 3D articles by placing sequential layers of diverse constituents. Among the extensive assortment of applications, Louis Vuitton has adapted this printing model to modernize their brand products. LV has constantly been the frontrunner in manufacturing high quality, high-end merchandises that customers religiously admire. In continuation this ongoing custom, LV designers are relentlessly looking for novel and enhanced mediums of supplying these goods to the customers. The application of modern technology, to embrace desktop 3D printing, will remain to be a crucial instrument in its expedition. This study also looks at the impact of LV’s first worldwide 3D printing outlet in Australia working hand-in-hand with specialist 3D print generator and how the brand is today likely to influence the usage of this 3D technology globally. The findings show that desktop 3D printing at LV has permitted scientists and producers at all of their locations to further experiment and be more creative in designing innovative and improvised fabrication techniques. New manufacturing methods applying 3D printing are effortlessly explored, executed at economic budgets to be then shared on collaborative terms with other LV manufacturing units globally, thus allowing easy transitions in fresh start-ups and manufacturing line changes as each new season approaches. [ABSTRACT FROM AUTHOR]

A study was conducted to estimate the energetics of base pairs in B-DNA in solution suing empirical potential energy functions. The structures were produced in the canonical B-DNA conformation using the BIOSYM computer software. A single structure was utilized to compare the performance of different parameter sets and dielectric frameworks. Results suggested the applicability of a sigmoidal function for solution conditions in implicit solvent treatments.