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This experimental study concerns the elimination of fluoride from water using an electrocoagulation reactor having a variable flow direction in favour of increasing the electrolysing time, saving the reactor area, and water mixing. The detention time of the space-saver EC reactor (S-SECR) was measured and compared to the traditional reactors using an inert dye (red drain dye). Then, the influence of electrical current (1.5 ≤ δ ≤ 3.5 mA cm−2), pH of water (4 ≤ pH ≤ 10), and distance between electrodes (5 ≤ ϕ ≤ 15) on the defluoridation of water was analysed. The effect of the electrolysing activity on the electrodes' morphology was studied using scanning electron microscopy (SEM). Additionally, the operational cost was calculated. The results confirmed the removal of fluoride using S-SECR met the guideline of the World Health Organization (WHO) for fluoride levels in drinking water of ≤1.5 mg/L. S-SECR abated fluoride concentration from 20 mg/L to the WHO's guideline at δ, ϕ, pH, operational cost, and power consumption of 2.5 mA cm−2, 5 mm, 7, 0.346 USD m−3, and 5.03 kWh m−3, respectively. It was also found the S-SECR enhanced the detention time by 190% compared to the traditional reactors. The appearance of dents and irregularities on the surface of anodes in the SEM images proves the electrolysing process.