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【目的】探讨常规体外受精胚胎移植（in vitro fertilization and embryo transfer,IVF-ET）不受精时,应用卵母细胞单精子显微注射（intracytoplasmic sperm injection,ICSI）技术进行补救授精的临床意义。【方法】2001年8月～2005年8月,在499个常规IVF-ET周期中有25个周期完全不受精,进行补救ICSI,并与同期实施的179个正常ICSI周期进行比较。【结果】补救ICSI组与正常ICSI组比较,HCG日平均血清雌二醇水平、每个成熟卵泡平均血清雌二醇量、每个周期的获卵数无明显差别,补救ICSI受精率为57.7%,低于正常ICSI组（67.8%）,补救ICSI组平均每个周期获得胚胎数（7.8±3.9）比正常ICSI（10.0±4.9）组少,且有统计学意义（P〈0.01）。补救ICSI组≥4细胞的胚胎占总胚胎数的54.5%,低于正常ICSI组（87.5%）,有统计学意义（P〈0.01）。正常ICSI组妊娠率为38.5%,补救ICSI组无一例妊娠。补救ICSI组中有8例在下一周期行ICSI,有2例妊娠并分娩2个健康女婴。【结论】补救ICSI虽可以避免取消IVF周期，但其受精率和妊娠率低，其临床应用价值还有待于进一步探讨。对于常规IVF不受精的患者，再次治疗时可考虑行ICSI助孕。

【目的】研究腹部超声引导下胚胎移植对体外受精-胚胎移植结局的影响。【方法】回顾性分析2001年7月至2005年3月，在本中心接受体外受精-胚胎移植（包括卵母细胞内单精子注射）治疗的461名患者521个周期的资料，按照胚胎移植时有无B超引导分为常规胚胎移植组（A组）和超声引导下胚胎移植组（B组），分别有187个周期和334个周期，比较两组患者的临床妊娠率、胚胎种植率、胚胎残留率和异位妊娠率。【结果】A组和B组的周期妊娠率分别是35．8％（67／187）和38.3％（128／334），P〉0．05；胚胎种植率分别是17．4％（104／599）和23．2％（179／773），P〈0．01；胚胎残留率分别是3．7％（7／187）和0．3％（1／334），P〈0．01；异位妊娠率分别是3．0％（2／67）和1．6％（2／128），P〉0．05。【结论】腹部超声引导下胚胎移植能提高体外受精-胚胎移植的胚胎种植率，降低胚胎残留率，可能有助于改善临床妊娠率和降低异位妊娠率，是一种有效的胚胎移植方法。

Objective To understand the influenza vaccination status of permanent residents in Macao and analyze the influencing factors. Methods A stratified cluster sampling method was employed to conduct a questionnaire survey of permanent residents in Macao from November 16 to 22, 2020. The survey primarily included basic knowledge of influenza, individual vaccination behavior, and vaccination status of family members. Chi-square tests and univariate and multivariate logistic regression models were utilized to explore the factors influencing public vaccination against influenza. Results A total of 2 207 residents participated in the survey, with males accounting for 45.3% and females accounting for 54.7%. In total, 62.1% of respondents reported having received the influenza vaccine in the past 12 months, and 61.0% of respondents exhibited a low level of knowledge regarding influenza. Multivariate logistic regression analysis indicated that the likelihood of receiving the influenza vaccine was higher among older individuals (aged over 50, OR=3.064, 95%CI: 1.114-7.814), those with fewer family members (1-2 members, OR=1.752, 95%CI: 1.323-2.320), those with a moderate monthly household income (40 000-60 000 yuan, OR=1.126, 95%CI: 1.852-1.489), individuals with higher educational attainment (higher education, OR=1.167, 95%CI: 1.949-1.434), those in high-risk professions (healthcare workers compared to civil servants, OR=2.730, 95%CI: 1.700-4.383), individuals in poorer health who were not pregnant (healthy individuals compared to pregnant patients, OR=2.060, 95%CI: 1.634-1.772; chronic disease patients, OR=2.623, 95%CI: 1.948-2.779), and those with a higher level of vaccine knowledge (OR=1.531, 95%CI: 1.069-2.194). Conclusion The influenza vaccination rate in Macao is relatively high on a global scale. However, there is still a need to strengthen educational outreach regarding influenza vaccination, encourage residents to get vaccinated, and actively promote collective vaccination activities in schools and institutions to fully utilize the role of community immunity. [ABSTRACT FROM AUTHOR]

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