Search

Monkeypox is a double-stranded DNA virus with an envelope and is a member of the Poxviridae family's Orthopoxvirus genus. This virus can transmit from human to human through direct contact with respiratory secretions, infected animals and humans, or contaminated objects and causing mutations in the human body. In May 2022, several monkeypox affected cases were found in many countries. Because of its transmitting characteristics, on July 23, 2022, a nationwide public health emergency was proclaimed by WHO due to the monkeypox virus. This study analyzed the gene mutation rate that is collected from the most recent NCBI monkeypox dataset. The collected data is prepared to independently identify the nucleotide and codon mutation. Additionally, depending on the size and availability of the gene dataset, the computed mutation rate is split into three categories: Canada, Germany, and the rest of the world. In this study, the genome mutation rate of the monkeypox virus is predicted using a deep learning-based Long Short-Term Memory (LSTM) model and compared with Gated Recurrent Unit (GRU) model. The LSTM model shows "Root Mean Square Error" (RMSE) values of 0.09 and 0.08 for testing and training, respectively. Using this time series analysis method, the prospective mutation rate of the 50th patient has been predicted. Note that this is a new report on the monkeypox gene mutation. It is found that the nucleotide mutation rates are decreasing, and the balance between bi-directional rates are maintained. [ABSTRACT FROM AUTHOR]

The COVID-19 pandemic has posed an ongoing threat to the mental wellbeing of countless individuals worldwide, with healthcare workers at particularly high risk. We developed the STEADY staff wellness program prior to the pandemic based on the available literature and input from stakeholders, guided by the Knowledge-to-Action (KTA) Implementation Science Framework. We quickly adapted the STEADY program for implementation in selected high-need units within Canada's largest trauma hospital during the pandemic's first wave. This brief report describes implementation of the STEADY program, retroactively applying the structure of the Knowledge-to-Action Implementation Science Framework to the practical steps taken. We identified the importance of more frequent, shorter contact with HCWs that occurred in-person, with an emphasis on peer support. A flexible approach with strong support from hospital leadership were key facilitators. Our findings suggest that a flexible approach to practical program implementation, theoretically underpinned in best-practices, can result in an acceptable program that promotes increased HCW wellbeing during a pandemic. [ABSTRACT FROM AUTHOR]

Background: More than half of adolescents have jobs in summer or sometime during the year. While employers are ultimately responsible for their safety, parents are often important in helping their children navigate the work environment. Our study examines the attitudes, beliefs and types of involvement parents have in their children's work.Methods: We modeled a telephone survey of 507 English-speaking parents of working adolescents in Ontario, Canada on a US study and examined their perspectives, comparing to earlier findings from the U.S. parents.Results: Most Ontario parents helped their teens consider questions to ask about work, for example, work hours (90.7%) and job tasks (78.2%) and fewer about workplace safety (57.9%). Parents overall were concerned about their teens, especially younger teens, getting behind on schoolwork (69.3%), being rushed on the job (60.1%) and doing hazardous tasks (58.3%) or working alone (51.9%), or being at work during a robbery (74.5%). Parents of 14-17-year-old daughters were more concerned about their child being assaulted than were parents of sons (62.4% vs. 51.4%), particularly if the teen was in the 18-19 age group (74.3% vs. 52.5%). Half the parents indicated 10-19 h per week was the right amount of work time for their teen, and most agreed that laws should limit the number of hours of youth work.Conclusions: Overall, Ontario parents appear to be more concerned about the safety and also more involved in the work of their adolescent children than U.S. parents previously surveyed. Parents are engaged with their children about their work and may serve as valuable assets to helping to advocate for safe work policies and environments. [ABSTRACT FROM AUTHOR]

This paper investigates the relationship between schedule instability and underemployment among hourly employees. The value to employers of specific hours of work often varies over short intervals, motivating variable scheduling and incomplete contracts that do not specify hours or availability. When employers offer variable weekly total hours, competition for scarce hours motivates employees to be available for work over a broader range of times. Workers may consequently be rewarded with more hours, but they garner fewer hours than their counterparts with stable hours. Cross-sectional analysis of the Canadian Workplace and Employee Survey demonstrates that underemployment is significantly more likely among hourly workers on unstable schedules. Longitudinal analysis indicates that even among the initially underemployed, who are strongly motivated to increase their availability, switching into an unstable schedule results in significantly fewer hours, providing evidence of employer-driven constraints on hours. There is no evidence of compensating differentials for unstable schedules. [ABSTRACT FROM AUTHOR]

Copyright of Canadian Journal of Statistics is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This paper deals with randomization methods for valuing American options written on dividend-paying assets, which are based on the idea of treating the maturity date as a random variable. In the randomization method introduced by Carr in 1998, he used the Erlangian distributed random variable to develop a recursive algorithm starting from the so-called Canadian option with an exponentially distributed random maturity. The purposes of this paper are (i) to provide much simpler pricing formulas for the Canadian option; (ii) to interpret the Gaver-Stehfest method developed for inverting Laplace transforms as an alternative randomization method in the context of valuing American options; and (iii) to evaluate the performance of the Gaver-Stehfest method in details with theoretical and numerical views. Numerical experiments indicate that the Gaver-Stehfest method works well to generate accurate approximations for the early exercise boundary as well as the option value. [ABSTRACT FROM AUTHOR]

Attrition, screening, and signalling models of strategic bargaining are characterized in terms of their predictions about the incidence, mean duration, and settlement rates of strikes and the terms of wage settlements. These predictions are compared with the general features observed in empirical studies of strikes in Canada and the United States. Conclusions are drawn about the types of models capable of generating these features, and about the conformity of the models to the evidence. Methods are described for computing the numerical examples used to illustrate the models. [ABSTRACT FROM AUTHOR]